Abstract
Background and purpose A sensitive and frequent clinical sign of a vestibular tone imbalance is the tilt of the perceived subjective visual vertical (SVV). There are no data yet focusing on lesion location at the cortical level as a factor for predicting compensation from the tilt of the SVV. Methods With modern voxelwise lesion behavior mapping analysis, the present study determines whether lesion location in 23 right-hemispheric cortical stroke patients with an otolith dysfunction could predict the compensation of a vestibular tone imbalance in the chronic stage. Results Our statistical anatomical lesion analysis revealed that lesions of the posterior insular cortex are involved in vestibular otolith compensation. Conclusion The insular cortex appears to be a critical anatomical region for predicting a tilt of the SVV as a chronic disorder in stroke patients.
Dokumententyp: | Zeitschriftenartikel |
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Fakultät: | Medizin
Medizin > Munich Cluster for Systems Neurology (SyNergy) |
Themengebiete: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit |
URN: | urn:nbn:de:bvb:19-epub-115252-3 |
ISSN: | 1351-5101 |
Sprache: | Englisch |
Dokumenten ID: | 115252 |
Datum der Veröffentlichung auf Open Access LMU: | 02. Apr. 2024, 08:11 |
Letzte Änderungen: | 10. Jun. 2024, 06:59 |
DFG: | Gefördert durch die Deutsche Forschungsgemeinschaft (DFG) - 406246813 |
DFG: | Gefördert durch die Deutsche Forschungsgemeinschaft (DFG) - 390857198 |