Case Series: Acute Hemorrhagic Encephalomyelitis After SARS-CoV-2 Vaccination

Ancau, Mihai; Liesche-Starnecker, Friederike; Niederschweiberer, Johanna; Krieg, Sandro M.; Zimmer, Claus; Lingg, Charlotte; Kumpfmueller, Daniela; Ikenberg, Benno; Ploner, Markus; Hemmer, Bernhard; Wunderlich, Silke; Muehlau, Mark und Knier, Benjamin (2022): Case Series: Acute Hemorrhagic Encephalomyelitis After SARS-CoV-2 Vaccination. In: Frontiers in Neurology, Bd. 12, 820049

Abstract

We present three cases fulfilling diagnostic criteria of hemorrhagic variants of acute disseminated encephalomyelitis (acute hemorrhagic encephalomyelitis, AHEM) occurring within 9 days after the first shot of ChAdOx1 nCoV-19. AHEM was diagnosed using magnetic resonance imaging, cerebrospinal fluid analysis and brain biopsy in one case. The close temporal association with the vaccination, the immune-related nature of the disease as well as the lack of other canonical precipitating factors suggested that AHEM was a vaccine-related adverse effect. We believe that AHEM might reflect a novel COVID-19 vaccine-related adverse event for which physicians should be vigilant and sensitized.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin > Munich Cluster for Systems Neurology (SyNergy)
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• Sprache: Englisch
• DFG: Gefördert durch die Deutsche Forschungsgemeinschaft (DFG) - 390857198