Logo Logo
Hilfe
Hilfe
Switch Language to English

Dormann, Dorothee (2020): FG-nucleoporins caught in the act of liquid-liquid phase separation. In: Journal of Cell Biology, Bd. 219, Nr. 1, e201910211 [PDF, 781kB]

Abstract

The interior of nuclear pore complexes (NPCs) is densely filled with FG-nucleoporins that form a permeability barrier of a still-obscure nature. Celetti et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201907157) now reveal that FG-nucleoporins can undergo liquid-liquid phase separation and form liquid droplets that mimic permeability barrier properties of intact NPCs.

Dokument bearbeiten Dokument bearbeiten