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Korn, Thomas ORCID logoORCID: https://orcid.org/0000-0002-3633-0955 (2024): An autoreactive T cell’s perception of a land of plenty. In: Immunity, Bd. 57, Nr. 10: P2258-2260 [PDF, 3MB]

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Abstract

Understanding the nature of human autoantigen-specific CD4+ T cells is limited by the difficulty of characterizing these cells ex vivo. In this issue of Immunity, Saggau et al. use ARTE technology to profile CD4+ T cells specific to disease-relevant autoantigens and find that such cells develop an exhausted phenotype that includes FOXP3 expression and persist for extended periods of time.

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