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Prestel, Matthias; Feller, Christian and Becker, Peter B. ORCID logoORCID: https://orcid.org/0000-0001-7186-0372 (2010): Dosage compensation and the global re-balancing of aneuploid genomes. In: Genome Biology 11:216 [PDF, 531kB]


Diploid genomes are exquisitely balanced systems of gene expression. The dosage-compensation systems that evolved along with monosomic sex chromosomes exemplify the intricacies of compensating for differences in gene copy number by transcriptional regulation.

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