Anzahl der Publikationen auf dieser Ebene: 72
2022
Li, Jian; Bergmann, Lena; Rafael de Almeida, Andreia; Webb, Kimberly M.; Gogol, Madelaine M.; Voigt, Philipp; Liu, Yingfang; Liang, Huanhuan und Smolle, Michaela M.
(21. Februar 2022):
H3K36 methylation and DNA-binding both promote Ioc4 recruitment and Isw1b remodeler function.
In: Nucleic Acids Research: S. 1-17
[PDF, 10MB]
Schmitt, Daniel; Bozkurt, Suleyman; Henning-Domres, Pascale; Huesmann, Heike; Eimer, Stefan; Bindila, Laura; Behrends, Christian; Boyle, Emily; Wilfling, Florian; Tascher, Georg; Munch, Christian; Behl, Christian und Kern, Andreas
(2022):
Lipid and protein content profiling of isolated native autophagic vesicles.
In: EMBO Reports, Bd. 23, Nr. 12
[PDF, 2MB]
Sekar, Revathi; Motzler, Karsten; Kwon, Yun; Novikoff, Aaron; Juelg, Julia; Najafi, Bahar; Wang, Surui; Warnke, Anna-Luisa; Seitz, Susanne; Hass, Daniela; Gancheva, Sofiya; Kahl, Sabine; Yang, Bin; Finan, Brian; Schwarz, Kathrin; Okun, Juergen G.; Roden, Michael; Blueher, Matthias; Mueller, Timo D.; Krahmer, Natalie; Behrends, Christian; Plettenburg, Oliver; Miaczynska, Marta; Herzig, Stephan und Zeigerer, Anja
(2022):
Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes.
In: Cell Metabolism, Bd. 34, Nr. 11: S. 1824-1842
[PDF, 7MB]
Wang, Zeyang; Fan, Rui; Russo, Angela; Cernilogar, Filippo M.; Nuber, Alexander; Schirge, Silvia; Shcherbakova, Irina; Dzhilyanova, Iva; Ugur, Enes; Anton, Tobias; Richter, Lisa; Leonhardt, Heinrich; Lickert, Heiko und Schotta, Gunnar
(19. September 2022):
Dominant role of DNA methylation over H3K9me3 for IAP silencing in endoderm.
In: Nature Communications, Bd. 13
[PDF, 5MB]
Williams, Luis A.; Gerber, David J.; Elder, Amy; Tseng, Wei Chou; Baru, Valeriya; Delaney-Busch, Nathaniel; Ambrosi, Christina; Mahimkar, Gauri; Joshi, Vaibhav; Shah, Himali; Harikrishnan, Karthiayani; Upadhyay, Hansini; Rajendran, Sakthi H.; Dhandapani, Aishwarya; Meier, Joshua; Ryan, Steven J.; Lewarch, Caitlin; Black, Lauren; Douville, Julie; Cinquino, Stefania; Legakis, Helen; Nalbach, Karsten; Behrends, Christian; Sato, Ai; Galluzzi, Lorenzo; Yu, Timothy W.; Brown, Duncan; Agrawal, Sudhir; Margulies, David; Kopin, Alan und Dempsey, Graham T.
(2022):
Developing antisense oligonucleotides for a TECPR2 mutation-induced, ultra-rare neurological disorder using patient-derived cellular models.
In: Molecular Therapy - Nucleic Acids, Bd. 29: S. 189-203
[PDF, 4MB]
2018
Andre, Viola; Gaut, Christine; Scheideler, Angelika; Aguilar-Pimentel, Juan A.; Amarie, Oana V.; Becker, Lore; Garrett, Lillian; Hans, Wolfgang; Hölter, Sabine M.; Janik, Dirk; Moreth, Kristin; Neff, Frauke; Östereicher, Manuela; Racz, Ildiko; Rathkolb, Birgit; Rozman, Jan; Bekeredjian, Raffi; Graw, Jochen; Klingenspor, Martin; Klopstock, Thomas; Ollert, Markus; Schmidt-Weber, Carsten; Wolf, Eckhard; Wurst, Wolfgang; Gailus-Durner, Valerie; Brielmeier, Markus; Fuchs, Helmut und Hrabe de Angelis, Martin
(2018):
Laboratory mouse housing conditions can be improved using common environmental enrichment without compromising data.
In: PLOS Biology
16(4), e2005019
[PDF, 5MB]
Fuchs, Helmut; Aguilar-Pimentel, Juan Antonio; Amarie, Oana V.; Becker, Lore; Calzada-Wack, Julia; Cho, Yi-Li; Garrett, Lillian; Hölter, Sabine M.; Irmler, Martin; Kistler, Martin; Kraiger, Markus; Mayer-Kuckuk, Philipp; Moreth, Kristin; Rathkolb, Birgit; Rozman, Jan; Silva Buttkus, Patricia da; Treise, Irina; Zimprich, Annemarie; Gampe, Kristine; Hutterer, Christine; Stoeger, Claudia; Leuchtenberger, Stefanie; Maier, Holger; Miller, Manuel; Scheideler, Angelika; Wu, Moya; Beckers, Johannes; Bekeredjian, Raffi; Brielmeier, Markus; Busch, Dirk H.; Klingenspor, Martin; Klopstock, Thomas; Ollert, Markus; Schmidt-Weber, Carsten; Stoeger, Tobias; Wolf, Eckhard; Wurst, Wolfgang; Yildirim, Ali Oender; Zimmer, Andreas; Gailus-Durner, Valerie und Hrabe de Angelis, Martin
(2018):
Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.
In: Behavioural Brain Research, Bd. 352: S. 187-196
Garrett, Lillian; Becker, Lore; Rozman, Jan; Puk, Oliver; Stoeger, Tobias; Yildirim, Ali Onder; Bohla, Alexander; Eickelberg, Oliver; Hans, Wolfgang; Prehn, Cornelia; Adamski, Jerzy; Klopstock, Thomas; Racz, Ildiko; Zimmer, Andreas; Klingenspor, Martin; Fuchs, Helmut; Gailus-Durner, Valerie; Wurst, Wolfgang; Hrabe de Angelis, Martin; Graw, Jochen und Hölter, Sabine M.
(2018):
Fgf9(Y162C) Mutation Alters Information Processing and Social Memory in Mice.
In: Molecular Neurobiology, Bd. 55, Nr. 6: S. 4580-4595
Rozman, Jan; Rathkolb, Birgit; Oestereicher, Manuela A.; Schütt, Christine; Ravindranath, Aakash Chavan; Leuchtenberger, Stefanie; Sharma, Sapna; Kistler, Martin; Willershaeuser, Monja; Brommage, Robert; Meehan, Terrence F.; Mason, Jeremy; Haselimashhadi, Hamed; Hough, Tertius; Mallon, Ann-Marie; Wells, Sara; Santos, Luis; Lelliott, Christopher J.; White, Jacqueline K.; Sorg, Tania; Champy, Marie-France; Bower, Lynette R.; Reynolds, Corey L.; Flenniken, Ann M.; Murray, Stephen A.; Nutter, Lauryl M. J.; Svenson, Karen L.; West, David; Tocchini-Valentini, Glauco P.; Beaudet, Arthur L.; Bosch, Fatima; Braun, Robert B.; Dobbie, Michael S.; Gao, Xiang; Herault, Yann; Moshiri, Ala; Moore, Bret A.; Lloyd, K. C. Kent; McKerlie, Colin; Masuya, Hiroshi; Tanaka, Nobuhiko; Flicek, Paul; Parkinson, Helen E.; Sedlacek, Radislav; Seong, Je Kyung; Wang, Chi-Kuang Leo; Moore, Mark; Brown, Steve D.; Tschoep, Matthias H.; Wurst, Wolfgang; Klingenspor, Martin; Wolf, Eckhard; Beckers, Johannes; Machicao, Fausto; Peter, Andreas; Staiger, Harald; Häring, Hans-Ulrich; Grallert, Harald; Campillos, Monica; Maier, Holger; Fuchs, Helmut; Gailus-Durner, Valerie; Werner, Thomas und Hrabe de Angelis, Martin
(2018):
Identification of genetic elements in metabolism by high-throughput mouse phenotyping.
In: Nature Communications, Bd. 9, 288
[PDF, 2MB]
Ryan, D. P.; Henzel, K. S.; Pearson, B. L.; Siwek, M. E.; Papazoglou, A.; Guo, L.; Paesler, K.; Yu, M.; Müller, R.; Xie, K.; Schröder, S.; Becker, L.; Garrett, L.; Hölter, S. M.; Neff, F.; Racz, I.; Rathkolb, B.; Rozman, J.; Ehninger, G.; Klingenspor, M.; Klopstock, T.; Wolf, E.; Wurst, W.; Zimmer, A.; Fuchs, H.; Gailus-Durner, V.; Hrabe de Angelis, Martin; Sidiropoulou, K.; Weiergräber, M.; Zhou, Y. und Ehninger, D.
(2018):
A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice.
In: Molecular Psychiatry, Bd. 23, Nr. 5: S. 1345-1355
Schnerwitzki, Danny; Perry, Sharn; Ivanova, Anna; Caixeta, Fabio V.; Cramer, Paul; Günther, Sven; Weber, Kathrin; Tafreshiha, Atieh; Becker, Lore; Panesso, Ingrid L. Vargas; Klopstock, Thomas; Hrabe de Angelis, Martin; Schmidt, Manuela; Kullander, Klas und Englert, Christoph
(2018):
Neuron-specific inactivation of Wt1 alters locomotion in mice and changes interneuron composition in the spinal cord.
In: Life Science Alliance, Bd. 1, Nr. 4, e201800106
[PDF, 2MB]
Zimprich, Annemarie; Ostereicher, Manuela A.; Becker, Lore; Dirscherl, Petra; Ernst, Luise; Fuchs, Helmut; Gailus-Durner, Valerie; Garrett, Lillian; Giesert, Florian; Glasl, Lisa; Hummel, Angelika; Rozman, Jan; Hrabe de Angelis, Martin; Vogt-Weisenhorn, Daniela; Wurst, Wolfgang und Hölter, Sabine M.
(2018):
Analysis of locomotor behavior in the German Mouse Clinic.
In: Journal of Neuroscience Methods, Bd. 300: S. 77-91
2016
Ben Halima, Saoussen; Mishra, Sabyashachi; Raja, K. Muruga Poopathi; Willem, Michael; Baici, Antonio; Simons, Kai; Bruestle, Oliver; Koch, Philipp; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Caflisch, Amedeo und Rajendran, Lawrence
(2016):
Specific Inhibition of beta-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein.
In: Cell Reports, Bd. 14, Nr. 9: S. 2127-2141
[PDF, 13MB]
Bowman, Andrew; Lercher, Lukas; Singh, Hari R.; Zinne, Daria; Timinszky, Gyula; Carlomagno, Teresa und Ladurner, Andreas G.
(2016):
The histone chaperone sNASP binds a conserved peptide motif within the globular core of histone H3 through its TPR repeats.
In: Nucleic Acids Research, Bd. 44, Nr. 7: S. 3105-3117
[PDF, 6MB]
Chung, Ho-Ryun; Xu, Chao; Fuchs, Alisa; Mund, Andreas; Lange, Martin; Staege, Hannah; Schubert, Tobias; Bian, Chuanbing; Dunkel, Ilona; Eberharter, Anton; Regnard, Catherine; Klinker, Henrike; Meierhofer, David; Cozzuto, Luca; Winterpacht, Andreas; Di Croce, Luciano; Min, Jinrong; Will, Hans und Kinkley, Sarah
(2016):
PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3.
In: eLife, Bd. 5, e10607
[PDF, 1MB]
Funke, Jonas J.; Ketterer, Philip; Lieleg, Corinna; Schunter, Sarah; Korber, Philipp und Dietz, Hendrik
(2016):
Uncovering the forces between nucleosomes using DNA origami.
In: Science Advances, Bd. 2, Nr. 11, e1600974
[PDF, 5MB]
Kretner, Benedikt; Trambauer, Johannes; Fukumori, Akio; Mielke, Janina; Kuhn, Peer-Hendrik; Kremmer, Elisabeth; Giese, Armin; Lichtenthaler, Stefan F.; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Arzberger, Thomas und Steiner, Harald
(2016):
Generation and deposition of A43 by the virtually inactive presenilin-1 L435F mutant contradicts the presenilin loss-of-function hypothesis of Alzheimer's disease.
In: Embo Molecular Medicine, Bd. 8, Nr. 5: S. 458-465
[PDF, 1MB]
Naujoks, Jan; Tabeling, Christoph; Dill, Brian D.; Hoffmann, Christine; Brown, Andrew S.; Kunze, Mareike; Kempa, Stefan; Peter, Andrea; Mollenkopf, Hans-Joachim; Dorhoi, Anca; Kershaw, Olivia; Gruber, Achim D.; Sander, Leif E.; Witzenrath, Martin; Herold, Susanne; Nerlich, Andreas; Hocke, Andreas C.; Driel, Ian van; Suttorp, Norbert; Bedoui, Sammy; Hilbi, Hubert; Trost, Matthias und Opitz, Bastian
(2016):
IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid.
In: PLOS Pathogens
12(2), e1005408
[PDF, 8MB]
Nelson, David M.; Jaber-Hijazi, Farah; Cole, John J.; Robertson, Neil A.; Pawlikowski, Jeffrey S.; Norris, Kevin T.; Criscione, Steven W.; Pchelintsev, Nikolay A.; Piscitello, Desiree; Stong, Nicholas; Rai, Taranjit Singh; McBryan, Tony; Otte, Gabriel L.; Nixon, Colin; Clark, William; Riethman, Harold; Wu, Hong; Schotta, Gunnar; Garcia, Benjamin A.; Neretti, Nicola; Baird, Duncan M.; Berger, Shelley L. und Adams, Peter D.
(2016):
Mapping H4K20me3 onto the chromatin landscape of senescent cells indicates a function in control of cell senescence and tumor suppression through preservation of genetic and epigenetic stability.
In: Genome Biology
17:158
[PDF, 2MB]
Rocha, Pedro P.; Raviram, Ramya; Fu, Yi; Kim, JungHyun; Luo, Vincent M.; Aljoufi, Arafat; Swanzey, Emily; Pasquarella, Alessandra; Balestrini, Alessia; Miraldi, Emily R.; Bonneau, Richard; Petrini, John; Schotta, Gunnar und Skok, Jane A.
(2016):
A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination.
In: Cell Reports, Bd. 16, Nr. 1: S. 48-55
[PDF, 7MB]
Xiang, Xianyuan; Werner, Georg; Bohrmann, Bernd; Liesz, Arthur; Mazaheri, Fargol; Capell, Anja; Feederle, Regina; Knuesel, Irene; Kleinberger, Gernot und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2016):
TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance.
In: Embo Molecular Medicine, Bd. 8, Nr. 9: S. 992-1004
[PDF, 1MB]
2015
Herweg, Jo-Ana; Hansmeier, Nicole; Otto, Andreas; Geffken, Anna C.; Subbarayal, Prema; Prusty, Bhupesh K.; Becher, Doerte; Hensel, Michael; Schaible, Ulrich E.; Rudel, Thomas und Hilbi, Hubert
(2015):
Purification and proteomics of pathogen-modified vacuoles and membranes.
In: Frontiers in Cellular and infection Microbiology, Bd. 5, 48
[PDF, 4MB]
Janssens, Jonathan; Philtjens, Stephanie; Kleinberger, Gernot; Mossevelde, Sara van; Zee, Julie van der; Cacace, Rita; Engelborghs, Sebastiaan; Sieben, Anne; Banzhaf-Strathmann, Julia; Dillen, Lubina; Merlin, Celine; Cuijt, Ivy; Robberecht, Caroline; Schmid, Bettina; Santens, Patrick; Ivanoiu, Adrian; Vandenbulcke, Mathieu; Vandenberghe, Rik; Cras, Patrick; De Deyn, Peter P.; Martin, Jean-Jacques; Maudsley, Stuart; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Cruts, Marc und Broeckhoven, Christine van
(2015):
Investigating the role of filamin C in Belgian patients with frontotemporal dementia linked to GRN deficiency in FTLD-TDP brains.
In: Acta Neuropathologica Communications
3:68
[PDF, 3MB]
2014
Burbulla, L. F.; Fitzgerald, J. C.; Stegen, K.; Westermeier, J.; Thost, A-K; Kato, H.; Mokranjac, D.; Sauerwald, J.; Martins, L. M.; Woitalla, D.; Rapaport, D.; Riess, O.; Proikas-Cezanne, T.; Rasse, T. M. und Krueger, R.
(2014):
Mitochondrial proteolytic stress induced by loss of mortalin function is rescued by Parkin and PINK1.
In: Cell Death & Disease, Bd. 5, e1180
[PDF, 7MB]
Gustems, Montse; Woellmer, Anne; Rothbauer, Ulrich; Eck, Sebastian H.; Wieland, Thomas; Lutter, Dominik und Hammerschmidt, Wolfgang
(2014):
c-Jun/c-Fos heterodimers regulate cellular genes via a newly identified class of methylated DNA sequence motifs.
In: Nucleic Acids Research, Bd. 42, Nr. 5: S. 3059-3072
[PDF, 2MB]
Lyons, David B.; Magklara, Angeliki; Goh, Tracie; Sampath, Srihari C.; Schaefer, Anne; Schotta, Gunnar und Lomvardas, Stavros
(2014):
Heterochromatin-Mediated Gene Silencing Facilitates the Diversification of Olfactory Neurons.
In: Cell Reports, Bd. 9, Nr. 3: S. 884-892
[PDF, 3MB]
Müller-Ott, Katharina; Erdel, Fabian; Matveeva, Anna; Mallm, Jan-Philipp; Rademacher, Anne; Hahn, Matthias; Bauer, Caroline; Zhang, Qin; Kaltofen, Sabine; Schotta, Gunnar; Hoefer, Thomas und Rippe, Karsten
(2014):
Specificity, propagation, and memory of pericentric heterochromatin.
In: Molecular Systems Biology, Bd. 10, Nr. 8
[PDF, 3MB]
Sansoni, Viola; Casas-Delucchi, Corella S.; Rajan, Malini; Schmidt, Andreas; Boenisch, Clemens; Thomae, Andreas W.; Staege, Martin S.; Hake, Sandra B.; Cardoso, M. Cristina und Imhof, Axel
(2014):
The histone variant H2A.Bbd is enriched at sites of DNA synthesis.
In: Nucleic Acids Research, Bd. 42, Nr. 10: S. 6405-6420
Toyoda, Yusuke; Erkut, Cihan; Pan-Montojo, Francisco; Boland, Sebastian; Stewart, Martin P.; Müller, Daniel J.; Wurst, Wolfgang; Hyman, Anthony A. und Kurzchalia, Teymuras V.
(2014):
Products of the Parkinson's disease-related glyoxalase DJ-1, D-lactate and glycolate, support mitochondrial membrane potential and neuronal survival.
In: Biology Open, Bd. 3, Nr. 8: S. 777-784
[PDF, 821kB]
Tuzon, Creighton T.; Spektor, Tanya; Kong, Xiaodong; Congdon, Lauren M.; Wu, Shumin; Schotta, Gunnar; Yokomori, Kyoko und Rice, Judd C.
(2014):
Concerted Activities of Distinct H4K20 Methyltransferases at DNA Double-Strand Breaks Regulate 53BP1 Nucleation and NHEJ-Directed Repair.
In: Cell Reports, Bd. 8, Nr. 2: S. 429-437
[PDF, 2MB]
2013
Jack, Antonia P. M.; Bussemer, Silva; Hahn, Matthias; Pünzeler, Sebastian; Snyder, Martha; Wells, Michael; Csankovszki, Gyorgyi; Solovei, Irina; Schotta, Gunnar und Hake, Sandra B.
(2013):
H3K56me3 is a novel, conserved heterochromatic mark that largely but not completely overlaps with H3K9me3 in both regulation and localization.
In: PLOS ONE
8(2), e51765
[PDF, 786kB]
McCarthy, James M.; Franke, Markus; Resenberger, Ulrike K.; Waldron, Sibeal; Simpson, Jeremy C.; Tatzelt, Jörg; Appelhans, Dietmar und Rogers, Mark S.
(2013):
Anti-prion drug mPPIg5 inhibits PrP(C) conversion to PrP(Sc).
In: PLOS ONE
8(1), e55282
[PDF, 1MB]
2012
Galati, Alessandra; Magdinier, Frédérique; Colasanti, Valentina; Bauwens, Serge; Pinte, Sébastien; Ricordy, Ruggero; Giraud-Panis, Marie-Josèphe; Pusch, Miriam Caroline; Savino, Maria; Cacchione, Stefano und Gilson, Eric
(2012):
TRF2 controls telomeric nucleosome organization in a cell cycle phase-dependent manner.
In: PLOS ONE
7(4), e34386
[PDF, 1MB]
2011
Boeke, Joern; Bag, Indira; Ramaiah, M. Janaki; Vetter, Irene; Kremmer, Elisabeth; Pal-Bhadra, Manika; Bhadra, Utpal und Imhof, Axel
(2011):
The RNA helicase Rm62 cooperates with SU(VAR)3-9 to re-silence active transcription in Drosophila melanogaster.
In: PLOS ONE
6(6), e20761
[PDF, 1MB]
Torrente, Mariana P.; Zee, Barry M.; Young, Nicolas L.; Baliban, Richard C.; LeRoy, Gary; Floudas, Christodoulos A.; Hake, Sandra B. und Garcia, Benjamin A.
(2011):
Proteomic interrogation of human chromatin.
In: PLOS ONE
6(9), e24747
[PDF, 900kB]
2010
2008
2006
Joy, Joma; Nalabothula, Narasimharao; Ghosh, Madhumita; Popp, Oliver; Jochum, Marianne; Machleidt, Werner; Gil-Parrado, Shirley und Holak, Tad A.
(2006):
Identification of calpain cleavage sites in the G1 cyclin-dependent kinase inhibitor p19(INK4d).
In: Biological Chemistry, Bd. 387, Nr. 3: S. 329-335
[PDF, 147kB]
Naus, Silvia; Reipschläger, Simone; Wildeboer, Dirk; Lichtenthaler, Stefan F.; Mitterreiter, Stefan; Guan, Ziqiang; Moss, Marcia L. und Bartsch, Jörg W.
(2006):
Identification of candidate substrates for ectodomain shedding by the metalloprotease-disintegrin ADAM8.
In: Biological Chemistry, Bd. 387, Nr. 3: S. 337-346
[PDF, 272kB]
2005
2004
2003
2000
1999
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