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Prestel, Matthias; Feller, Christian; Becker, Peter B.: Dosage compensation and the global re-balancing of aneuploid genomes. In: Genome Biology 2010, 11:216
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Abstract

Diploid genomes are exquisitely balanced systems of gene expression. The dosage-compensation systems that evolved along with monosomic sex chromosomes exemplify the intricacies of compensating for differences in gene copy number by transcriptional regulation.