RIG-I-Like Receptors: One STrEP Forward

Lässig, Charlotte und Hopfnerl, Karl-Peter (2016): RIG-I-Like Receptors: One STrEP Forward. In: Trends in Microbiology, Bd. 24, Nr. 7: S. 517-519

Abstract

RIG-I-like receptors detect cytosolic viral RNA and activate an antiviral innate immune response. A new study employs the one STrEP-purification technique and next generation sequencing to characterize physiological ligands in an infected cell. The view of all three RLRs bound to viral RNAs shows specialization, collaboration and new binding sites.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Chemie und Pharmazie > Department Biochemie
• Themengebiete: 500 Naturwissenschaften und Mathematik > 540 Chemie
• ISSN: 0966-842X
• Sprache: Englisch