Department of Biochemistry

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  - Department of Biochemistry (565)

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Number of items at this level: 565.

2022

Hohle, Markus Matthias; Lammens, Katja; Gut, Fabian; Wang, Bingzhi; Kahler, Sophia; Kugler, Kathrin; Till, Michael; Beckmann, Roland; Hopfner, Karl-Peter and Jung, Christophe (12. September 2022): Ice thickness monitoring for cryo-EM grids by interferometry imaging. In: Scientific Reports, Vol. 12 [PDF, 2MB]

Kunert, Franziska; Metzner, Felix J.; Jung, James; Höpfler, Markus; Woike, Stephan; Schall, Kevin; Kostrewa, Dirk; Moldt, Manuela; Chen, Jia-Xuan; Bantele, Susanne; Pfander, Boris; Eustermann, Sebastian and Hopfner, Karl-Peter (2022): Structural mechanism of extranucleosomal DNA readout by the INO80 complex. In: Science Advances, Vol. 8, No. 49 [PDF, 3MB]

Metzner, Felix J.; Huber, Elisabeth; Hopfner, Karl-Peter and Lammens, Katja (2022): Structural and biochemical characterization of human Schlafen 5. In: Nucleic Acids Research, Vol. 50, No. 2: pp. 1147-1161 [PDF, 4MB]

Pinci, Francesca; Gaidt, Moritz M.; Jung, Christophe; Nagl, Dennis; Kuut, Gunnar and Hornung, Veit (12. December 2022): Tumor necrosis factor is a necroptosis-associated alarmin. In: Frontiers in Immunology, Vol. 13 [PDF, 7MB]

Qi, Zhan; Jung, Christophe; Bandilla, Peter; Ludwig, Claudia; Heron, Mark; Sophie Kiesel, Anja; Museridze, Mariam; Philippou‐Massier, Julia; Nikolov, Miroslav; Renna Max Schnepf, Alessio; Unnerstall, Ulrich; Ceolin, Stefano; Mühlig, Bettina; Gompel, Nicolas; Soeding, Johannes and Gaul, Ulrike (14. February 2022): Large‐scale analysis of Drosophila core promoter function using synthetic promoters. In: Molecular Systems Biology, Vol. 18, No. 2 [PDF, 3MB]

Stafford, Che A.; Gassauer, Alicia-Marie; Oliveira Mann, Carina C. de; Tanzer, Maria C.

; Fessler, Evelyn; Wefers, Benedikt

; Nagl, Dennis; Kuut, Gunnar; Sulek, Karolina; Vasilopoulou, Catherine; Schwojer, Sophia J.

; Wiest, Andreas

; Pfautsch, Marie K.; Wurst, Wolfgang

; Yabal, Monica

; Fröhlich, Thomas

; Mann, Matthias

; Gisch, Nicolas

; Jae, Lucas T.

and Hornung, Veit

(2022): Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation. In: Nature, Vol. 609: pp. 590-596 [PDF, 10MB]

Tanasie, Nicoleta-Loredana; Gutiérrez-Escribano, Pilar; Jaklin, Sigrun; Aragon, Luis and Stigler, Johannes (6. December 2022): Stabilization of DNA fork junctions by Smc5/6 complexes revealed by single-molecule imaging. In: Cell Reports, Vol. 41, No. 10 [PDF, 4MB]

Wilde, Magdalena; Brehm, Julian; Schwarzer, Michael; Stöckl, Jan Bernd; Laforsch, Christian and Fröhlich, Thomas (2022): Improving the proteome coverage of Daphnia magna - implications for future ecotoxicoproteomics studies. In: Proteomics, Vol. 22, No. 10 [PDF, 929kB]

2021

Alminana, Carmen; Rudolf Vegas, Alba; Tekin, Muhittin; Hassan, Mubbashar; Uzbekov, Rustem; Frohlich, Thomas; Bollwein, Heinrich and Bauersachs, Stefan (2021): Isolation and Characterization of Equine Uterine Extracellular Vesicles: A Comparative Methodological Study. In: International Journal of Molecular Sciences, Vol. 22, No. 2, 979

Altstetter, Sebastian Maximilian; Quitt, Oliver; Pinci, Francesca; Hornung, Veit; Lucko, Aaron Michael; Wisskirchen, Karin; Jung, Stephanie and Protzer, Ulrike (2021): Hepatitis-D Virus Infection Is Not Impaired by Innate Immunity but Increases Cytotoxic T-Cell Activity. In: Cells, Vol. 10, No. 11, 3253

Bandera, Adrian M.; Bartho, Joseph; Lammens, Katja; Drexler, David Jan; Kleinschwaerzer, Jasmin; Hopfner, Karl-Peter and Witte, Gregor (2021): BusR senses bipartite DNA binding motifs by a unique molecular ruler architecture. In: Nucleic Acids Research, Vol. 49, No. 17: pp. 10166-10177

Bauernfried, Stefan and Hornung, Veit (2021): DPP9 restrains NLRP1 activation. In: Nature Structural & Molecular Biology, Vol. 28, No. 4: pp. 333-336

Bottcher, Romy; Schmidts, Ines; Nitschko, Volker; Duric, Petar and Förstemann, Klaus (2021): RNA polymerase II is recruited to DNA double-strand breaks for dilncRNA transcription in Drosophila. In: Rna Biology, Vol. 19, No. 1: pp. 68-77

Brandt, Margot; Kim-Hellmuth, Sarah; Ziosi, Marcello; Gokden, Alper; Wolman, Aaron; Lam, Nora; Recinos, Yocelyn; Daniloski, Zharko; Morris, John A.; Hornung, Veit; Schumacher, Johannes and Lappalainen, Tuuli (2021): An autoimmune disease risk variant: A trans master regulatory effect mediated by IRF1 under immune stimulation?
In: PLOS Genetics 17(7), e1009684

Caballero, Ignacio; Ringot-Destrez, Belinda; Si-Tahar, Mustapha; Barbry, Pascal; Guillon, Antoine; Lantier, Isabelle; Berri, Mustapha; Chevaleyre, Claire; Fleurot, Isabelle; Barc, Celine; Ramphal, Reuben; Pons, Nicolas; Paquet, Agnes; Lebrigand, Kevin; Baron, Carole; Baehr, Andrea; Klymiuk, Nikolai; Leonard, Renaud and Robbe-Masselot, Catherine (2021): Evidence of early increased sialylation of airway mucins and defective mucociliary clearance in CFTR-deficient piglets. In: Journal of Cystic Fibrosis, Vol. 20, No. 1: pp. 173-182

Do, Van Hoan and Canzar, Stefan (2021): A generalization of t-SNE and UMAP to single-cell multimodal omics. In: Genome Biology, Vol. 22, No. 1, 130

Do, Van Hoan; Ringeling, Francisca Rojas and Canzar, Stefan (2021): Linear-time cluster ensembles of large-scale single-cell RNA-seq and multimodal data Van Hoan Do, Francisca Rojas Ringeling, and Stefan Canzar. In: Genome Research, Vol. 31, No. 4: pp. 677-688

Eckl, Eva-Maria; Ziegemann, Olga; Krumwiede, Luisa; Fessler, Evelyn and Jae, Lucas T. (2021): Sensing, signaling and surviving mitochondrial stress. In: Cellular and Molecular Life Sciences, Vol. 78, No. 16: pp. 5925-5951

Freitag, Marvin; Kamp, Dieter; Synakewicz, Marie and Stigler, Johannes (2021): Identification and correction of miscalibration artifacts based on force noise for optical tweezers experiments. In: Journal of Chemical Physics, Vol. 155, No. 17, 175101

Ghosh, Suvoshree; Kraus, Katrin; Biswas, Arijit; Mueller, Jens; Forin, Francesco; Singer, Heike; Höning, Klara; Hornung, Veit; Watzka, Matthias; Oldenburg, Johannes and Czogalla-Nitsche, Katrin J. (2021): GGCX variants leading to biallelic deficiency to gamma-carboxylate GRP cause skin laxity in VKCFD1 patients. In: Human Mutation, Vol. 43, No. 1: pp. 42-55

Ghosh, Suvoshree; Kraus, Katrin; Biswas, Arijit; Müller, Jens; Buhl, Anna-Lena; Forin, Francesco; Singer, Heike; Höning, Klara; Hornung, Veit; Watzka, Matthias; Czogalla-Nitsche, Katrin J. and Oldenburg, Johannes (2021): GGCX mutations show different responses to vitamin K thereby determining the severity of the hemorrhagic phenotype in VKCFD1 patients. In: Journal of Thrombosis and Haemostasis, Vol. 19, No. 6: pp. 1412-1424

Heiss, Matthias; Borland, Kayla; Yoluç, Yasemin and Kellner, Stefanie (2021): Quantification of Modified Nucleosides in the Context of NAIL-MS. In: McMahon, Mary (ed.) : RNA Modifications. Methods in Molecular Biology, Vol. 2298. pp. 279-306

Hnizda, Ales; Tesina, Petr; Nguyen, Thanh-Binh; Kukacka, Zdenek; Kater, Lukas; Chaplin, Amanda; Beckmann, Roland; Ascher, David B.; Novak, Petr and Blundell, Tom L. (2021): SAP domain forms a flexible part of DNA aperture in Ku70/80. In: Febs Journal, Vol. 288, No. 14: pp. 4382-4393

Huang, Bin; Guo, Qiang; Niedermeier, Marie L.; Cheng, Jingdong; Engler, Tatjana; Maurer, Melanie; Pautsch, Alexander; Baumeister, Wolfgang; Stengel, Florian; Kochanek, Stefan and Fernandez-Busnadiego, Ruben (2021): Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex. In: Structure, Vol. 29, No. 8: pp. 804-809

Kirstein, Nina; Buschle, Alexander; Wu, Xia; Krebs, Stefan; Blum, Helmut; Kremmer, Elisabeth; Vorberg, Ina M.; Hammerschmidt, Wolfgang; Lacroix, Laurent; Hyrien, Olivier; Audit, Benjamin and Schepers, Aloys (2021): Human ORC/MCM density is low in active genes and correlates with replication time but does not delimit initiation zones. In: eLife, Vol. 10, e62161 [PDF, 1MB]

Kratzat, Hanna; Mackens‐Kiani, Timur; Ameismeier, Michael; Potocnjak, Mia; Cheng, Jingdong; Dacheux, Estelle; Namane, Abdelkader; Berninghausen, Otto; Herzog, Franz

; Fromont‐Racine, Micheline; Becker, Thomas and Beckmann, Roland (2021): A structural inventory of native ribosomal ABCE1‐43S pre‐initiation complexes. In: EMBO, Vol. 40, No. 1 [PDF, 12MB]

Latoscha, Andreas; Drexler, David Jan; Witte, Gregor and Tschowri, Natalia (2021): Assessment of Diadenylate Cyclase and c-di-AMP-phosphodiesterase Activities Using Thin-layer and Ion Exchange Chromatography. In: Bio-Protocol, Vol. 11, No. 1, e3870

Lenz, Jonathan; Liefke, Robert; Funk, Julianne; Shoup, Samuel; Nist, Andrea; Stiewe, Thorsten; Schulz, Robert; Tokusumi, Yumiko; Albert, Lea; Raifer, Hartmann; Foerstemann, Klaus; Vazquez, Olalla; Tokusumi, Tsuyoshi; Fossett, Nancy and Brehm, Alexander (2021): Ush regulates hemocyte-specific gene expression, fatty acid metabolism and cell cycle progression and cooperates with dNuRD to orchestrate hematopoiesis.
In: PLOS Genetics 17(2), e1009318

Li, Xiaoling; Fetter, Richard; Schwabe, Tina; Jung, Christophe; Liu, Liren; Steller, Hermann and Gaul, Ulrike (2021): The cAMP effector PKA mediates Moody GPCR signaling in Drosophila blood-brain barrier formation and maturation. In: eLife, Vol. 10, e68275 [PDF, 13MB]

Li-Leger, Erica; Feichtinger, Richard; Flibotte, Stephane; Holzkamp, Heinke; Schnabel, Ralf and Moerman, Donald G. (2021): Identification of essential genes in Caenorhabditis elegans through whole-genome sequencing of legacy mutant collections. In: G3-Genes Genomes Genetics, Vol. 11, No. 12, jkab328

Linnekamp, Janneke F.; Kandimalla, Raju; Fessler, Evelyn; Jong, Joan H. de; Rodermond, Hans M.; Bochove, Gregor G. W. van; The, Frans O.; Punt, Cornelis J. A.; Bemelman, Willem A.; Ven, Anthony W. H. van de; Tanis, Pieter J.; Kemper, Elles M.; Koens, Lianne; Dekker, Evelien; Vermeulen, Louis; Laarhoven, Hanneke W. M. van and Medema, Jan Paul (2021): Pre-Operative Decitabine in Colon Cancer Patients: Analyses on WNT Target Methylation and Expression. In: Cancers, Vol. 13, No. 10, 2357

Liu, Zikou; Dagley, Laura F.; Shield-Artin, Kristy; Young, Samuel N.; Bankovacki, Aleksandra; Wang, Xiangyi; Tang, Michelle; Howitt, Jason; Stafford, Che A.; Nachbur, Ueli; Fitzgibbon, Cheree; Garnish, Sarah E.; Webb, Andrew I.; Komander, David; Murphy, James M.; Hildebrand, Joanne M. and Silke, John (2021): Oligomerization-driven MLKL ubiquitylation antagonizes necroptosis. In: EMBO Journal, Vol. 40, No. 23, e103718

Mertes, Christian; Scheller, Ines F.; Yepez, Vicente A.; Celik, Muhammed H.; Liang, Yingjiqiong; Kremer, Laura S.; Gusic, Mirjana; Prokisch, Holger and Gagneur, Julien (2021): Detection of aberrant splicing events in RNA-seq data using FRASER. In: Nature Communications, Vol. 12, No. 1, 529

Nynca, J.; Zarski, D.; Froehlich, T.; Köster, M.; Bobe, J. and Ciereszko, A. (2021): Comparative proteomic analysis reveals the importance of the protective role of ovarian fluid over eggs during the reproduction of pikeperch. In: Aquaculture, Vol. 548, 737656

Oberbeckmann, Elisa; Niebauer, Vanessa; Watanabe, Shinya; Farnung, Lucas; Moldt, Manuela; Schmid, Andrea; Cramer, Patrick; Peterson, Craig L.; Eustermann, Sebastian; Hopfner, Karl-Peter and Korber, Philipp (2021): Ruler elements in chromatin remodelers set nucleosome array spacing and phasing. In: Nature Communications, Vol. 12, No. 1, 3232

Oliveira Mann, Carina C. de and Hopfner, Karl-Peter (2021): Nuclear cGAS: guard or prisoner? In: EMBO Journal, Vol. 40, No. 16, e108293

Oliveira Mann, Carina C. de and Hornung, Veit (2021): Molecular mechanisms of nonself nucleic acid recognition by the innate immune system. In: European Journal of Immunology, Vol. 51, No. 8: pp. 1897-1910

Pochopien, Agnieszka A.; Beckert, Bertrand; Kasvandik, Sergo; Berninghausen, Otto; Beckmann, Roland; Tenson, Tanel and Wilson, Daniel N. (2021): Structure of Gcn1 bound to stalled and colliding 80S ribosomes. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, No. 14, e2022756118

Rabanal-Ruiz, Yoana; Byron, Adam; Wirth, Alexander; Madsen, Ralitsa; Sedlackova, Lucia; Hewitt, Graeme; Nelson, Glyn; Stingele, Julian; Wills, Jimi C.; Zhang, Tong; Zeug, Andre; Faessler, Reinhard; Vanhaesebroeck, Bart; Maddocks, Oliver D. K.; Ponimaskin, Evgeni; Carroll, Bernadette and Korolchuk, Viktor (2021): mTORC1 activity is supported by spatial association with focal adhesions. In: Journal of Cell Biology, Vol. 220, No. 5, e202004010

Sakata, Eri; Eisele, Markus R. and Baumeister, Wolfgang (2021): Molecular and cellular dynamics of the 26S proteasome. In: Biochimica et Biophysica Acta-Proteins and Proteomics, Vol. 1869, No. 3, 140583

Scheu, Arne H. A.; Lim, Sheryl Y. T.; Metzner, Felix J.; Mohammed, Shabaz and Howarth, Mark (2021): NeissLock provides an inducible protein anhydride for covalent targeting of endogenous proteins. In: Nature Communications, Vol. 12, No. 1, 717

Shashikadze, Bachuki; Flenkenthaler, Florian; Stöckl, Jan B.; Valla, Libera; Renner, Simone; Kemter, Elisabeth; Wolf, Eckhard and Fröhlich, Thomas (2021): Developmental Effects of (Pre-)Gestational Diabetes on Offspring: Systematic Screening Using Omics Approaches. In: Genes, Vol. 12, No. 12, 1991

Shen, Lunda; Su, Zhaoming; Yang, Kailu; Wu, Cheng; Becker, Thomas; Bell-Pedersen, Deborah; Zhang, Junjie and Sachs, Matthew S. (2021): Structure of the translating Neurospora ribosome arrested by cycloheximide. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, No. 48, e2111862118

Stakyte, K.; Rotheneder, M.; Lammens, K.; Bartho, J. D.; Grädler, U.; Fuchß, T.; Pehl, U.; Alt, A.; Logt, E. van de and Hopfner, K. P. (2021): Molecular basis of human ATM kinase inhibition. In: Nature Structural & Molecular Biology, Vol. 28, No. 10: 789-

Tahk, Siret; Vick, Binje; Hiller, Björn; Schmitt, Saskia; Marcinek, Anetta; Perini, Enrico D.; Leutbecher, Alexandra; Augsberger, Christian; Reischer, Anna; Tast, Benjamin; Humpe, Andreas; Jeremias, Irmela; Subklewe, Marion; Fenn, Nadja C. and Hopfner, Karl-Peter (2021): SIRP alpha-alpha CD123 fusion antibodies targeting CD123 in conjunction with CD47 blockade enhance the clearance of AML-initiating cells. In: Journal of Hematology & Oncology, Vol. 14, No. 1, 155

(2021): SIRPα-αCD123 fusion antibodies targeting CD123 in conjunction with CD47 blockade enhance the clearance of AML-initiating cells. In: Journal of hematology & oncology, Vol. 14, 155 [PDF, 3MB]

Trotter, Benjamin; Wilde, Magdalena; Brehm, Julian; Dafni, Evdokia; Aliu, Arlinda; Arnold, Georg J.; Fröhlich, Thomas and Laforsch, Christian (2021): Long-term exposure of Daphnia magna to polystyrene microplastic (PS-MP) leads to alterations of the proteome, morphology and life-history. In: Science of the Total Environment, Vol. 795, 148822

Wolf, E. and Reichart, B. (2021): Xenotransplantation solider Organe. In: Nephrologe, Vol. 16, No. 3: pp. 138-144

Wratil, Paul R.; Schmacke, Niklas A.; Karakoc, Burak; Dulovic, Alex; Junker, Daniel; Becker, Matthias; Rothbauer, Ulrich; Osterman, Andreas; Spaeth, Patricia M.; Ruhle, Adrian; Gapp, Madeleine; Schneider, Stephanie; Muenchhoff, Maximilian; Hellmuth, Johannes C.; Scherer, Clemens; Mayerle, Julia; Reincke, Martin; Behr, Jürgen; Kaab, Stefan; Zwissler, Bernhard; Bergwelt-Baildon, Michael von; Eberle, Josef; Kaderali, Lars; Schneiderhan-Marra, Nicole; Hornung, Veit and Keppler, Oliver T. (2021): Evidence for increased SARS-CoV-2 susceptibility and COVID-19 severity related to pre-existing immunity to seasonal coronaviruses. In: Cell Reports, Vol. 37, No. 13, 110169

Yepez, Vicente A.; Mertes, Christian; Mueller, Michaela F.; Klaproth-Andrade, Daniela; Wachutka, Leonhard; Fresard, Laure; Gusic, Mirjana; Scheller, Ines F.; Goldberg, Patricia F.; Prokisch, Holger and Gagneur, Julien (2021): Detection of aberrant gene expression events in RNA sequencing data. In: Nature Protocols, Vol. 16, No. 2

Zhao, Shubo; Kieser, Anja; Li, Hao-Yi; Reinking, Hannah K.; Weickert, Pedro; Euteneuer, Simon; Yaneva, Denitsa; Acampora, Aleida C.; Goetz, Maximilian J.; Feederle, Regina and Stingele, Julian (2021): A ubiquitin switch controls autocatalytic inactivation of the DNA-protein crosslink repair protease SPRTN. In: Nucleic Acids Research, Vol. 49, No. 2

2020

Ameismeier, Michael; Zemp, Ivo; Heuvel, Jasmin van den; Thoms, Matthias; Berninghausen, Otto; Kutay, Ulrike and Beckmann, Roland (2020): Structural basis for the final steps of human 40S ribosome maturation. In: Nature, Vol. 587, No. 7835: pp. 683-687

Basu, Aakash; Bobrovnikov, Dmitriy G.; Qureshi, Zan; Kayikcioglu, Tunc; Ngo, Thuy T. M.; Ranjan, Anand; Eustermann, Sebastian; Cieza, Basilio; Morgan, Michael T.; Hejna, Miroslav; Rube, H. Tomas; Hopfner, Karl-Peter; Wolberger, Cynthia; Song, Jun S. and Ha, Taekjip (2020): Measuring DNA mechanics on the genome scale. In: Nature, Vol. 589, No. 7842: pp. 462-467

Blagotinsek, Vitan; Schwan, Meike; Steinchen, Wieland; Mrusek, Devid; Hook, John C.; Rossmann, Florian; Freibert, Sven A.; Kratzat, Hanna; Murat, Guillaume; Kressler, Dieter; Beckmann, Roland; Beeby, Morgan; Thormann, Kai M. and Bange, Gert (2020): An ATP-dependent partner switch links flagellar C-ring assembly with gene expression. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 34: pp. 20826-20835

Brea, Deborah; Soler, Laura; Fleurot, Isabelle; Melo, Sandrine; Chevaleyre, Claire; Berri, Mustapha; Labas, Valerie; Teixeira-Gomes, Ana-Paula; Pujo, Julien; Cenac, Nicolas; Baehr, Andrea; Klymiuk, Nikolai; Guillon, Antoine; Si-Tahar, Mustapha and Caballero, Ignacio (2020): Intrinsic alterations in peripheral neutrophils from cystic fibrosis newborn piglets. In: Journal of Cystic Fibrosis, Vol. 19, No. 5: pp. 830-836

Buschauer, Robert; Matsuo, Yoshitaka; Sugiyama, Takato; Chen, Ying-Hsin; Alhusaini, Najwa; Sweet, Thomas; Ikeuchi, Ken; Cheng, Jingdong; Matsuki, Yasuko; Nobuta, Risa; Gilmozzi, Andrea; Berninghausen, Otto; Tesina, Petr; Becker, Thomas; Coller, Jeff; Inada, Toshifumi and Beckmann, Roland (2020): The Ccr4-Not complex monitors the translating ribosome for codon optimality. In: Science, Vol. 368, No. 6488, eaay6912

Ceolin, Stefano; Hanf, Monika; Bozek, Marta; Storti, Andrea Ennio; Gompel, Nicolas; Unnerstall, Ulrich; Jung, Christophe and Gaul, Ulrike (2020): A sensitive mNeonGreen reporter system to measure transcriptional dynamics in Drosophila development. In: Communications Biology, Vol. 3, No. 1, 663

Chakraborty, Shounak; Canzar, Stefan; Marschall, Tobias and Schulz, Marcel H. (2020): Chromatyping: Reconstructing Nucleosome Profiles from NOMe Sequencing Data. In: Journal of Computational Biology, Vol. 27, No. 3: pp. 330-341

Cheng, Jingdong; Lau, Benjamin; La Venuta, Giuseppe; Ameismeier, Michael; Berninghausen, Otto; Hurt, Ed and Beckmann, Roland (2020): 90S pre-ribosome transformation into the primordial 40S subunit. In: Science, Vol. 369, No. 6510: pp. 1470-1476

Cunha Bustamante-Filho, Ivan; Renato Menegassi, Silvio; Ribas Pereira, Gabriel; Dias Salton, Gabrielle; Mosena Munari, Fernanda; Roberto Schneider, Marlon; Costa Mattos, Rodrigo; Otavio Jardim Barcellos, Julio; Pereira Laurino, Jomar; Obino Cirne-Lima, Elizabeth and Ines Mascarenhas Jobim, Maria (2020): Bovine seminal plasma osteopontin: Structural modelling, recombinant expression and its relationship with semen quality. In: Andrologia, Vol. 53, No. 1, e13905

Do, Van Hoan; Elbassioni, Khaled and Canzar, Stefan (2020): Sphetcher: Spherical Thresholding Improves Sketching of Single-Cell Transcriptomic Heterogeneity. In: Iscience, Vol. 23, No. 6, 101126

Fessler, Evelyn; Eckl, Eva-Maria; Schmitt, Sabine; Mancilla, Igor Alves; Meyer-Bender, Matthias F.; Hanf, Monika; Philippou-Massier, Julia; Krebs, Stefan; Zischka, Hans and Jae, Lucas T. (2020): A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol. In: Nature, Vol. 579, No. 7799: pp. 433-437

Gegenfurtner, Katrin; Fröhlich, Thomas; Flenkenthaler, Florian; Koesters, Miwako; Fritz, Sebastien; Desnoes, Olivier; Le Bourhis, Daniel; Salvetti, Pascal; Sandra, Olivier; Charpigny, Gilles; Mermillod, Pascal; Lonergan, Patrick; Wolf, Eckhard and Arnold, Georg J. (2020): Genetic merit for fertility alters the bovine uterine luminal fluid proteome. In: Biology of Reproduction, Vol. 102, No. 3: pp. 730-739

Ghodgaonkar-Steger, Medini; Potocnjak, Mia; Zimniak, Tomasz; Fischböck-Halwachs, Josef; Solis-Mezarino, Victor; Singh, Sylvia; Speljko, Tea; Hagemann, Götz; Drexler, David Jan; Witte, Gregor and Herzog, Franz

(2020): C-Terminal Motifs of the MTW1 Complex Cooperatively Stabilize Outer Kinetochore Assembly in Budding Yeast. In: Cell reports, Vol. 32, No. 13, 108190 [PDF, 5MB]

Haass, Christian

and Sewald, Bettina (19. December 2020): Weder Gans noch Rotwein schmecken. In: Münchner Merkur Ausgabe Geretsrieder Merkur, No. 294: p. 4

Helfrich, Anika L.; Reichenbach, Horst-Dieter; Meyerholz, Marie M.; Schoon, Heinz-Adolf; Arnold, Georg J.; Fröhlich, Thomas; Weber, Frank and Zerbe, Holm (2020): Novel sampling procedure to characterize bovine subclinical endometritis by uterine secretions and tissue. In: Theriogenology, Vol. 141: pp. 186-196

Hinrichs, Arne; Riedel, Evamaria O.; Klymiuk, Nikolai; Blutke, Andreas; Kemter, Elisabeth; Laengin, Matthias; Dahlhoff, Maik; Kessler, Barbara; Kurome, Mayuko; Zakhartchenko, Valeri; Jemiller, Eva-Maria; Ayares, David; Bidlingmaier, Martin; Flenkenthaler, Florian; Hrabe de Angelis, Martin; Arnold, Georg J.; Reichart, Bruno; Fröhlich, Thomas and Wolf, Eckhard (2020): Growth hormone receptor knockout to reduce the size of donor pigs for preclinical xenotransplantation studies. In: Xenotransplantation, Vol. 28, No. 2, e12664

Hoesl, Christine; Zanuttigh, Enrica; Fröhlich, Thomas; Philippou-Massier, Julia; Krebs, Stefan; Blum, Helmut and Dahlhoff, Maik (2020): The secretome of skin cancer cells activates the mTOR/MYC pathway in healthy keratinocytes and induces tumorigenic properties. In: Biochimica et Biophysica Acta-Molecular Cell Research, Vol. 1867, No. 8, 118717

Hopfner, Karl-Peter

and Hornung, Veit

(18. May 2020): Molecular mechanisms and cellular functions of cGAS-STING signalling. In: Nature Reviews Molecular Cell Biology, Vol. 21: pp. 501-521 [PDF, 13MB]

Huppertz, Christine; Jager, Benedikt; Wieczorek, Grazyna; Engelhard, Peggy; Oliver, Stephen J.; Bauernfeind, Franz-Georg; Littlewood-Evans, Amanda; Welte, Tobias; Hornung, Veit and Prasse, Antje (2020): The NLRP3 inflammasome pathway is activated in sarcoidosis and involved in granuloma formation. In: European Respiratory Journal, Vol. 55, No. 3, 1900119

Jansma, Marijke; Linke-Winnebeck, Christian; Eustermann, Sebastian; Lammens, Katja; Kostrewa, Dirk; Stakyte, Kristina; Litz, Claudia; Kessler, Brigitte and Hopfner, Karl-Peter (2020): Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State. In: Structure, Vol. 28, No. 1: pp. 83-95

Kater, Lukas; Mitterer, Valentin; Thoms, Matthias; Cheng, Jingdong; Berninghausen, Otto; Beckmann, Roland and Hurt, Ed (2020): Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis. In: Molecular Cell, Vol. 79, No. 4: pp. 615-628

Kater, Lukas; Wagener, Nikola; Berninghausen, Otto; Becker, Thomas; Neupert, Walter and Beckmann, Roland (2020): Structure of the Bcs1 AAA-ATPase suggests an airlock-like translocation mechanism for folded proteins. In: Nature Structural & Molecular Biology, Vol. 27, No. 2: pp. 142-149

Kemter, Elisabeth; Schnieke, Angelika; Fischer, Konrad; Cowan, Peter J. and Wolf, Eckhard (2020): Xeno-organ donor pigs with multiple genetic modifications - the more the better? In: Current Opinion in Genetics & Development, Vol. 64: pp. 60-65

Killinger, Kerstin; Boehm, Miriam; Steinbach, Philine; Hagemann, Goetz; Blueggel, Mike; Jaenen, Karolin; Hohoff, Simone; Bayer, Peter; Herzog, Franz and Westermann, Stefan (2020): Auto-inhibition of Mif2/CENP-C ensures centromere-dependent kinetochore assembly in budding yeast. In: EMBO Journal, Vol. 39, No. 14, e102938

Koepke, Lennart; Winter, Benjamin; Grenzner, Alexander; Regensburger, Kerstin; Engelhart, Susanne; Merwe, Johannes A. van der; Krebs, Stefan; Blum, Helmut; Kirchhoff, Frank and Sparrer, Konstantin M. J. (2020): An improved method for high-throughput quantification of autophagy in mammalian cells. In: Scientific Reports, Vol. 10, No. 1, 12241 [PDF, 6MB]

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Vogel, Heike; Kamitz, Anne; Hallahan, Nicole; Lebek, Sandra; Schallschmidt, Tanja; Jonas, Wenke; Jaehnert, Markus; Gottmann, Pascal; Zellner, Lisa; Kanzleiter, Timo; Damen, Mareike; Altenhofen, Delsi; Burkhardt, Ralph; Renner, Simone; Dahlhoff, Maik; Wolf, Eckhard; Müller, Timo D.; Blueher, Matthias; Joost, Hans-Georg; Chadt, Alexandra; Al-Hasani, Hadi and Schürmann, Annette (2018): A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and Type 2 diabetes. In: Human Molecular Genetics, Vol. 27, No. 17: pp. 3099-3112

Westbye, Alexander B.; Kater, Lukas; Wiesmann, Christina; Ding, Hao; Yip, Calvin K. and Beatty, J. Thomas (2018): The Protease ClpXP and the PAS Domain Protein DivL Regulate CtrA and Gene Transfer Agent Production in Rhodobacter capsulatus. In: Applied and Environmental Microbiology, Vol. 84, No. 11

Xie, Kan; Ryan, Devon P.; Pearson, Brandon L.; Henzel, Kristin S.; Neff, Frauke; Vidal, Ramon O.; Hennion, Magali; Lehmann, Isabelle; Schleif, Melvin; Schröder, Susanne; Adler, Thure; Rathkolb, Birgit; Rozman, Jan; Schütz, Anna-Lena; Prehn, Cornelia; Mickael, Michel E.; Weiergraber, Marco; Adamski, Jerzy; Busch, Dirk H.; Ehninger, Gerhard; Matynia, Anna; Jackson, Walker S.; Wolf, Eckhard; Fuchs, Helmut; Gailus-Durner, Valerie; Bonn, Stefan; Hrabe de Angelis, Martin and Ehninger, Dan (2018): Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 10, E2348-E2357 [PDF, 2MB]

Yepez, Vicente A.; Kremer, Laura S.; Iuso, Arcangela; Gusic, Mirjana; Kopajtich, Robert; Konarikova, Eliska; Nadel, Agnieszka; Wachutka, Leonhard; Prokisch, Holger and Gagneur, Julien (2018): OCR-Stats: Robust estimation and statistical testing of mitochondrial respiration activities using Seahorse XF Analyzer.
In: PLOS One 13(7), e0199938 [PDF, 3MB]

2017

Ahdash, Zainab; Byrne, Robert; Hopfner, Karl-Peter and Politis, Argyris (2017): Dissecting the Mechanism of the HerA NurA DNA Break Resection Complex using Native Mass Spectrometry. In: Biophysical Journal, Vol. 112, No. 3: 515A-515A

Albisetti, Gioele W.; Ghanem, Alexander; Foster, Edmund; Conzelmann, Karl-Klaus; Zeilhofer, Hanns Ulrich and Wildner, Hendrik (2017): Identification of Two Classes of Somatosensory Neurons That Display Resistance to Retrograde Infection by Rabies Virus. In: Journal of Neuroscience, Vol. 37, No. 43: pp. 10358-10371

Andreeva, Liudmila; Hiller, Björn; Kostrewa, Dirk; Lässig, Charlotte; Oliveira Mann, Carina C. de; Drexler, David Jan; Maiser, Andreas; Gaidt, Moritz; Leonhardt, Heinrich; Hornung, Veit and Hopfner, Karl-Peter (2017): cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders. In: Nature, Vol. 549, No. 7672: pp. 394-398

Antonopoulos, Alexios; Psarros, Konstantinos; Abdesselem, Mouna; Szolc, Piotr and Baeuerle, Patrick (2017): Dr Patrick Baeuerle, MPMCapital, talks with young scientists. In: Cardiovascular Research, Vol. 113, No. 12, E42-E42

Arduino, Daniela M.; Wettmarshausen, Jennifer; Vais, Horia; Navas-Navarro, Paloma; Cheng, Yiming; Leimpek, Anja; Ma, Zhongming; Delrio-Lorenzo, Alba; Giordano, Andrea; Garcia-Perez, Cecilia; Medard, Guillaume; Kuster, Bernhard; Garcia-Sancho, Javier; Mokranjac, Dejana; Foskett, J. Kevin; Teresa Alonso, M. and Perocchi, Fabiana (2017): Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening. In: Molecular Cell, Vol. 67, No. 4: pp. 711-723

Ayoubian, Hiresh; Fröhlich, Thomas; Pogodski, Dagmar; Flatley, Andrew; Kremmer, Elisabeth; Schepers, Aloys; Feederle, Regina; Arnold, Georg J. and Grässer, Friedrich A. (2017): Antibodies against the mono-methylated arginine-glycine repeat (MMA-RG) of the Epstein-Barr virus nuclear antigen 2 (EBNA2) identify potential cellular proteins targeted in viral transformation. In: Journal of General Virology, Vol. 98, No. 8: pp. 2128-2142

Baejen, Carlo; Andreani, Jessica; Torkler, Phillipp; Battaglia, Sofia; Schwalb, Bjoern; Lidschreiber, Michael; Maier, Kerstin C.; Boltendahl, Andrea; Rus, Petra; Esslinger, Stephanie; Söding, Johannes and Cramer, Patrick (2017): Genome-wide Analysis of RNA Polymerase II Termination at Protein-Coding Genes. In: Molecular Cell, Vol. 66, No. 1: pp. 38-49

Batelli, Sara; Kremer, Malte; Jung, Christophe and Gaul, Ulrike (2017): Application of MultiColor FlpOut Technique to Study High Resolution Single Cell Morphologies and Cell Interactions of Glia in Drosophila. In: Jove-Journal of Visualized Experiments, No. 128, e56177

Bauersachs, Stefan; Simintiras, Constantine A.; Sturmey, Roger G.; Krebs, Stefan; Bick, Jochen; Blum, Helmut; Wolf, Eckhard; Lonergan, Pat and Forde, Niamh (2017): Effect of metabolic status on conceptus-maternal interactions on day 19 in dairy cattle: II. Effects on the endometrial transcriptome. In: Biology of Reproduction, Vol. 97, No. 3: pp. 413-425

Baum, Rebecca; Sharma, Shruti; Organ, Jason M.; Jakobs, Christopher; Hornung, Veit; Burr, David B.; Marshak-Rothstein, Ann; Fitzgerald, Katherine A. and Gravallese, Ellen M. (2017): STING Contributes to Abnormal Bone Formation Induced by Deficiency of DNase II in Mice. In: Arthritis & Rheumatology, Vol. 69, No. 2: pp. 460-471

Beckert, Bertrand; Abdelshahid, Maha; Schäfer, Heinrich; Steinchen, Wieland; Arenz, Stefan; Berninghausen, Otto; Beckmann, Roland; Bange, Gert; Turgay, Kürsad and Wilson, Daniel N. (2017): Structure of the Bacillus subtilis hibernating 100S ribosome reveals the basis for 70S dimerization. In: Embo Journal, Vol. 36, No. 14: pp. 2061-2072

Bhat, Javaid Y.; Milicic, Goran; Thieulin-Pardo, Gabriel; Bracher, Andreas; Maxwell, Andrew; Ciniawsky, Susanne; Müller-Cajar, Oliver; Engen, John R.; Hartl, F. Ulrich; Wendler, Petra and Hayer-Hartl, Manajit (2017): Mechanism of Enzyme Repair by the AAA(+) Chaperone Rubisco Activase. In: Molecular Cell, Vol. 67, No. 5: pp. 744-756

Blaj, Cristina; Bringmann, Agnes; Schmidt, Eva Marina; Urbischek, Manuela; Lamprecht, Sebastian; Fröhlich, Thomas; Arnold, Georg J.; Krebs, Stefan; Blum, Helmut; Hermeking, Heiko; Jung, Andreas; Kirchner, Thomas and Horst, David (2017): ADNP Is a Therapeutically Inducible Repressor of WNT Signaling in Colorectal Cancer. In: Clinical Cancer Research, Vol. 23, No. 11: pp. 2769-2780

Blutke, Andreas; Renner, Simone; Flenkenthaler, Florian; Backman, Mattias; Häsner, Serena; Kemter, Elisabeth; Ländström, Erik; Braun-Reichhart, Christina; Albl, Barbara; Streckel, Elisabeth; Rathkolb, Birgit; Prehn, Cornelia; Palladini, Alessandra; Grzybek, Michal; Krebs, Stefan; Bauersachs, Stefan; Bähr, Andrea; Brühschwein, Andreas

; Deeg, Cornelia A.; Monte, Erica de; Dmochewitz, Michaela; Eberle, Caroline; Emrich, Daniela; Fux, Robert; Groth, Frauke; Gumbert, Sophie; Heitmann, Antonia; Hinrichs, Arne; Kessler, Barbara; Kurome, Mayuko; Leipig-Rudolph, Miriam; Matiasek, Kaspar; Öztürk, Hazal; Otzdorff, Christiane; Reichenbach, Myriam; Reichenbach, Horst Dieter; Rieger, Alexandra; Rieseberg, Birte; Rosati, Marco; Saucedo, Manuel Nicolas; Schleicher, Anna; Schneider, Marlon R.; Simmet, Kilian; Steinmetz, Judith; Übel, Nicole; Zehetmaier, Patrizia; Jung, Andreas; Adamski, Jerzy; Coskun, Ünal; Hrabe de Angelis, Martin; Simmet, Christian; Ritzmann, Mathias; Meyer-Lindenberg, Andrea; Blum, Helmut; Arnold, Georg J.; Fröhlich, Thomas; Wanke, Rüdiger and Wolf, Eckhard (2017): The Munich MIDY Pig Biobank - A unique resource for studying organ crosstalk in diabetes. In: Molecular Metabolism, Vol. 6, No. 8: pp. 931-940

Bougas, Anthony; Vlachogiannis, Ioannis A.; Gatos, Dimitrios; Arenz, Stefan and Dinos, George P. (2017): Dual effect of chloramphenicol peptides on ribosome inhibition. In: Amino Acids, Vol. 49, No. 5: pp. 995-1004

Brockmann, Markus; Blomen, Vincent A.; Nieuwenhuis, Joppe; Stickel, Elmer; Raaben, Matthijs; Bleijerveld, Onno B.; Altelaar, A. F. Maarten; Jae, Lucas T. and Brummelkamp, Thijn R. (2017): Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling. In: Nature, Vol. 546, No. 7657: pp. 307-311

Bröckl, S.; Krebs, S.; Varadharajan, A.; Straubinger, R. K.; Blum, H. and Büttner, M. (2017): Investigation of intra-herd spread of Mycobacterium caprae in cattle by generation and use of a whole-genome sequence. In: Veterinary Research Communications, Vol. 41, No. 2: pp. 113-128

Brönner, Cornelia; Salvi, Luca; Zocco, Manuel; Ugolini, Ilaria and Halic, Mario (2017): Accumulation of RNA on chromatin disrupts heterochromatic silencing. In: Genome Research, Vol. 27, No. 7: pp. 1174-1183

Böttcher, Ralph T.; Veelders, Maik; Rombaut, Pascaline; Faix, Jan; Theodosiou, Marina; Stradal, Theresa E.; Rottner, Klemens; Zent, Roy; Herzog, Franz

and Faessler, Reinhard (2017): Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading. In: Journal of Cell Biology, Vol. 216, No. 11: pp. 3785-3798

Cheng, Jingdong; Kellner, Nikola; Berninghausen, Otto; Hurt, Ed and Beckmann, Roland (2017): 3.2-angstrom-resolution structure of the 90S preribosome before A1 pre-rRNA cleavage. In: Nature Structural & Molecular Biology, Vol. 24, No. 11: pp. 954-964

Cheng, Jun; Maier, Kerstin C.; Avsec, Ziga; Rus, Petra and Gagneur, Julien (2017): Cis-regulatory elements explain most of the mRNA stability variation across genes in yeast. In: Rna, Vol. 23, No. 11: pp. 1648-1659

Costanzi, M.; Krupka, C.; Kischel, R.; Kufer, P.; Köhnke, T.; Spiekermann, K.; Hiddemann, W. and Subklewe, M. (2017): Secretion Of Soluble Factors By AML Cells Influence CD33/CD3 BITE (R) Antibody Mediated Cytotoxicity And T-Cell Proliferation. In: Haematologica, Vol. 102: pp. 357-358

Czogalla, Katrin J.; Biswas, Arijit; Höning, Klara; Hornung, Veit; Liphardt, Kerstin; Watzka, Matthias and Oldenburg, Johannes (2017): Warfarin and vitamin K compete for binding to Phe55 in human VKOR. In: Nature Structural & Molecular Biology, Vol. 24, No. 1: pp. 77-85

Decker, Tim-Michael; Kluge, Michael; Krebs, Stefan; Shah, Nilay; Blum, Helmut; Friedel, Caroline C. and Eick, Dirk (2017): Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of small molecule inhibitor JQ1. In: Scientific Reports, Vol. 7, 1684 [PDF, 1MB]

Douglass, Amelia M.; Kucukdereli, Hakan; Ponserre, Marion; Markovic, Milica; Gründemann, Jan; Strobel, Cornelia; Morales, Pilar L. Alcala; Conzelmann, Karl-Klaus; Lüthi, Andreas and Klein, Rüdiger (2017): Central amygdala circuits modulate food consumption through a positive-valence mechanism. In: Nature Neuroscience, Vol. 20, No. 10: pp. 1384-1394

Drexler, David Jan; Müller, Martina; Rojas-Cordova, Carlos Alberto; Bandera, Adrian Maurice and Witte, Gregor (2017): Structural and Biophysical Analysis of the Soluble DHH/DHHA1-Type Phosphodiesterase TM1595 from Thermotoga maritima. In: Structure, Vol. 25, No. 12: pp. 1887-1897

Eichhorn, S.; Mendoza, A.; Prinzing, A.; Stroh, A.; Xinghai, L.; Polski, M.; Heller, M.; Lahm, H.; Wolf, E.; Lange, R. and Krane, M. (2017): Corpuls CPR Generates Higher Mean Arterial Pressure Than LUCAS II in a Pig Model of Cardiac Arrest. In: Biomed Research international, Vol. 2017, 5470406 [PDF, 2MB]

Engel, Christina; Brügmann, Grethe; Lambing, Silke; Mühlenbeck, Larissa H.; Marx, Samira; Hagen, Christian; Horvath, Dorottya; Goldeck, Marion; Ludwig, Janos; Herzner, Anna-Maria; Drijfhout, Jan W.; Wenzel, Daniela; Coch, Christoph; Tüting, Thomas; Schlee, Martin; Hornung, Veit; Hartmann, Gunther and Boorn, Jasper G. van den (2017): RIG-I Resists Hypoxia-Induced Immunosuppression and Dedifferentiation. In: Cancer Immunology Research, Vol. 5, No. 6: pp. 455-467

Farias-Rico, Jose Arcadio; Götz, Sara Kathrin; Marino, Jacopo and Heijne, Gunnar von (2017): Mutational analysis of protein folding inside the ribosome exit tunnel. In: Febs Letters, Vol. 591, No. 1: pp. 155-163

Flenkenthaler, F.; Schmid, N.; Froehlich, T.; Dietrich, K.; Schwarzer, J. U.; Mayerhofer, A. and Arnold, G. J. (2017): Quantitative proteomics reveals cellular senescence of human testicular peritubular cells. In: Reproduction in Domestic Animals, Vol. 52: p. 17

Florin, Tanja; Maracci, Cristina; Graf, Michael; Karki, Prajwal; Klepacki, Dorota; Berninghausen, Otto; Beckmann, Roland; Vazquez-Laslop, Nora; Wilson, Daniel N.; Rodnina, Marina V. and Mankin, Alexander S. (2017): An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome. In: Nature Structural & Molecular Biology, Vol. 24, No. 9: pp. 752-757

Florin, Tanja; Maracci, Cristina; Graf, Michael; Karki, Prajwal; Klepacki, Dorota; Rodnina, Marina V.; Wilson, Daniel N.; Vazquez-Laslop, Nora and Mankin, Alexander S. (2017): Antimicrobial Peptide Turns the Ribosome into a Release Factor Trap. In: FASEB Journal, Vol. 31

Gaidt, Moritz M.; Ebert, Thomas S.; Chauhan, Dhruv; Ramshorn, Katharina; Pinci, Francesca; Zuber, Sarah; O'Duill, Fionan; Schmid-Burgk, Jonathan L.; Hoss, Florian; Buhmann, Raymund; Wittmann, Georg; Latz, Eicke; Subklewe, Marion and Hornung, Veit (2017): The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3. In: Cell, Vol. 171, No. 5: pp. 1110-1124

Gaidt, Moritz M. and Hornung, Veit (2017): Alternative inflammasome activation enables IL-1 beta release from living cells. In: Current Opinion in Immunology, Vol. 44: pp. 7-13

Ghosh, Sreya; Wallerath, Christina; Covarrubias, Sergio; Hornung, Veit; Carpenter, Susan and Fitzgerald, Katherine A. (2017): The PYHIN Protein p205 Regulates the Inflammasome by Controlling Asc Expression. In: Journal of Immunology, Vol. 199, No. 9: pp. 3249-3260

Glaser, Laura V.; Rieger, Simone; Thumann, Sybille; Beer, Sophie; Kuklik-Roos, Cornelia; Martin, Dietmar E.; Maier, Kerstin C.; Harth-Hertle, Marie L.; Grüning, Björn; Backofen, Rolf; Krebs, Stefan; Blum, Helmut; Zimmer, Ralf; Erhard, Florian and Kempkes, Bettina (2017): EBF1 binds to EBNA2 and promotes the assembly of EBNA2 chromatin complexes in B cells.
In: PLOS Pathogens 13(10), e1006664 [PDF, 8MB]

Graf, Michael; Arenz, Stefan; Huter, Paul; Dönhöfer, Alexandra; Novacek, Jiri and Wilson, Daniel N. (2017): Cryo-EM structure of the spinach chloroplast ribosome reveals the location of plastid-specific ribosomal proteins and extensions. In: Nucleic Acids Research, Vol. 45, No. 5: pp. 2887-2896

Graf, Michael; Mardirossian, Mario; Nguyen, Fabian; Seefeldt, A. Carolin; Guichard, Gilles; Scocchi, Marco; Innis, C. Axel and Wilson, Daniel N. (2017): Proline-rich antimicrobial peptides targeting protein synthesis. In: Natural Product Reports, Vol. 34, No. 7: pp. 702-711

Graf, S. A.; Heppt, M. V.; Krebs, S.; Kammerbauer, C.; Hornig, E.; Strieder, A.; Blum, H. and Berking, C. (2017): Peripheral myelin protein 2 is a target gene of the transcription factor SOX10 in melanoma and affects tumor cell invasion. In: Experimental Dermatology, Vol. 26, No. 3, E91-E92

Göbel, J.; Ghanem, A.; Motori, E.; Jahn, H. M.; Wani, G.; Conzelmann, K.-K. and Bergami, M. (2017): Perivascular remodeling of astrocytic ER and mitochondrial networks following brain injury. In: Glia, Vol. 65, E526-E526

Gürtler, Patrick; Krebs, Stefan; Blum, Helmut and Busch, Ulrich (2017): Anwendung der Next Generation Sequencing Technologie in der GVO-Analytik. In: Journal für Verbraucherschutz und Lebensmittelsicherheit-Journal of Consumer Protection and Food Safety, Vol. 12: S57-S60

Hambaryan, V.; Suleimanov, V.; Haberl, F.; Schwope, A. D.; Neuhäuser, R.; Hohle, M. and Werner, K. (2017): The compactness of the isolated neutron star RX J0720.4-3125. In: Astronomy & Astrophysics, Vol. 601, A108

Hedegger, K.; Krebs, S.; Graf, A.; Kunzelmann, S.; Blum, H.; Wolf, E. and Dahlhoff, M. (2017): Peri-conceptional overweight in male and female mice causes sex-specific transcriptome changes in blastocysts which could result from differential expressed sncRNA in spermatozoa of obese males. In: Reproduction in Domestic Animals, Vol. 52: p. 22

Hedgethorne, Katy; Eustermann, Sebastian; Yang, Ji-Chun; Ogden, Tom E. H.; Neuhaus, David and Bloomfield, Gareth (2017): Homeodomain-like DNA binding proteins control the haploid-to-diploid transition in Dictyostelium. In: Science Advances, Vol. 3, No. 9, e1602937

Heininen-Brown, M.; Graf, A.; Wünsch, A.; Zakhartchenko, V.; Mallok, S.; Krebs, S.; Wolf, E. and Blum, H. (2017): Study of the impact of somatic cell nuclear transfer (SCNT) on transcriptome of early bovine embryos. In: Reproduction in Domestic Animals, Vol. 52: p. 23

Heink, Sylvia; Yogev, Nir; Garbers, Christoph; Herwerth, Marina; Aly, Lilian; Gasperi, Christiane; Husterer, Veronika; Croxford, Andrew L.; Möller-Hackbarth, Katja; Bartsch, Harald S.; Sotlar, Karl; Krebs, Stefan; Regen, Tommy; Blum, Helmut; Hemmer, Bernhard; Misgeld, Thomas; Wunderlich, Thomas F.; Hidalgo, Juan; Oulcka, Mohamed; Rose-John, Stefan; Schmidt-Supprian, Marc; Waisman, Ari and Korn, Thomas (2017): Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic T(H)17 cells. In: Nature Immunology, Vol. 18, No. 1: pp. 74-85

Hermanns, C.; Hampl, V.; Holzer, K.; Aigner, A.; Penkava, J.; Frank, N.; Martin, D. E.; Maier, K. C.; Waldburger, N.; Rössler, S.; Goppelt-Struebe, M.; Akrap, I.; Thavamani, A.; Singer, S.; Nordheim, A.; Gudermann, T. and Mühlich, S. (2017): The novel MKL target gene myoferlin modulates expansion and senescence of hepatocellular carcinoma. In: Oncogene, Vol. 36, No. 24: pp. 3464-3476

Herold, Tobias; Jurinovic, V.; Metzeler, K. H.; Batcha, A. M. N.; Bamopoulos, S. A.; Rothenberg-Thurley, M.; Ksienzyk, B.; Hartmann, L.; Greif, P. A.; Phillippou-Massier, J.; Krebs, S.; Blum, H.; Amler, S.; Schneider, S.; Konstandin, N.; Sauerland, M. C.; Berdel, W. E.; Wörmann, B. J.; Subklewe, M.; Fiegl, M.; Bohlander, S. K.; Braess, J.; Hiddemann, W.; Mansmann, Ulrich and Spiekermann, K. (2017): Prediction of Primary Refractory Acute Myeloid Leukemia. In: Annals of Hematology, Vol. 96: S25-S25

Heuer, Andre; Gerovac, Milan; Schmidt, Christian; Trowitzsch, Simon; Preis, Anne; Kötter, Peter; Berninghausen, Otto; Becker, Thomas; Beckmann, Roland and Tampe, Robert (2017): Structure of the 40S-ABCE1 post-splitting complex in ribosome recycling and translation initiation. In: Nature Structural & Molecular Biology, Vol. 24, No. 5: pp. 453-460

Heuer, Andre; Thomson, Emma; Schmidt, Christian; Berninghausen, Otto; Becker, Thomas; Hurt, Ed and Beckmann, Roland (2017): Cryo-EM structure of a late pre-40S ribosomal subunit from Saccharomyces cerevisiae. In: Elife, Vol. 6, e30189 [PDF, 7MB]

Heuser, Christoph; Gotot, Janine; Piotrowski, Eveline Christina; Philipp, Marie-Sophie; Courreges, Christina Johanna Felicia; Otte, Martin Sylvester; Guo, Linlin; Schmid-Burgk, Jonathan Leo; Hornung, Veit; Heine, Annkristin; Knolle, Percy Alexander; Garbi, Natalio; Serfling, Edgar; Evaristo, Cesar; Thaiss, Friedrich and Kurts, Christian (2017): Prolonged IKK beta Inhibition Improves Ongoing CTL Antitumor Responses by Incapacitating Regulatory T Cells. In: Cell Reports, Vol. 21, No. 3: pp. 578-586

Hinkel, Rabea; Höwe, Andrea; Renner, Simone; Ng, Judy; Lee, Seungmin; Klett, Katharina; Kaczmarek, Veronika; Moretti, Alessandra; Laugwitz, Karl-Ludwig; Skroblin, Philipp; Mayr, Manuel; Milting, Hendrik; Dendorfer, Andreas; Reichart, Bruno; Wolf, Eckhard and Kupatt, Christian (2017): Diabetes Mellitus-Induced Microvascular Destabilization in the Myocardium. In: Journal of the American College of Cardiology, Vol. 69, No. 2: pp. 131-143

Hinrichs, A.; Kessler, B.; Kurome, M.; Rathkolb, B.; Blum, W.; Scholz, A.; Bernau, M.; Blutke, A.; Dahlhoff, M. and Wolf, E. (2017): Impaired weight gain and disproportionate organ growth, but preserved fertility in growth hormone receptor deficient pigs (Laron syndrome). In: Reproduction in Domestic Animals, Vol. 52: p. 24

Honrath, Birgit; Matschke, Lina; Meyer, Tammo; Magerhans, Lena; Perocchi, Fabiana; Ganjam, Goutham K.; Zischka, Hans; Krasel, Cornelius; Gerding, Albert; Bakker, Barbara M.; Bünemann, Moritz; Strack, Stefan; Decher, Niels; Culmsee, Carsten and Dolga, Amalia M. (2017): SK2 channels regulate mitochondrial respiration and mitochondrial Ca2+ uptake. In: Cell Death and Differentiation, Vol. 24, No. 5: pp. 761-773

Huter, Paul; Arenz, Stefan; Bock, Lars V.; Graf, Michael; Frister, Jan Ole; Heuer, Andre; Peil, Lauri; Starosta, Agata L.; Wohlgemuth, Ingo; Peske, Frank; Novacek, Jiri; Berninghausen, Otto; GrubMüller, Helmut; Tenson, Tanel; Beckmann, Roland; Rodnina, Marina V.; Vaiana, Andrea C. and Wilson, Daniel N. (2017): Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P. In: Molecular Cell, Vol. 68, No. 3: pp. 515-527

Huter, Paul; Müller, Claudia; Beckert, Bertrand; Arenz, Stefan; Berninghausen, Otto; Beckmann, Roland and Wilson, Daniel N. (2017): Structural basis for ArfA-RF2-mediated translation termination on mRNAs lacking stop codons. In: Nature, Vol. 541, No. 7638

Ivic, Nives; Bilokapic, Silvija and Halic, Mario (2017): Preparative two-step purification of recombinant H1.0 linker histone and its domains.
In: PLOS One 12(12), e0189040 [PDF, 1MB]

Karakatsani, Andromachi; Marichal, Nicolas; Urban, Severino; Kalamakis, Georgios; Ghanem, Alexander; Schick, Anna; Zhang, Yina; Conzelmann, Karl-Klaus; Rüegg, Markus A.; Berninger, Benedikt; Ruiz de Almodovar, Carmen; Gascon, Sergio and Kröger, Stephan (2017): Neuronal LRP4 regulates synapse formation in the developing CNS. In: Development, Vol. 144, No. 24: pp. 4604-4615

Karlstetter, Marcus; Kopatz, Jens; Aslanidis, Alexander; Shahraz, Anahita; Caramoy, Albert; Linnartz-Gerlach, Bettina; Lin, Yuchen; Lückoff, Anika; Fauser, Sascha; Düker, Katharina; Claude, Janine; Wang, Yiner; Ackermann, Johannes; Schmidt, Tobias; Hornung, Veit; Skerka, Christine; Langmann, Thomas and Neumann, Harald (2017): Polysialic acid blocks mononuclear phagocyte reactivity, inhibits complement activation, and protects from vascular damage in the retina. In: Embo Molecular Medicine, Vol. 9, No. 2: pp. 154-166

Kater, Lukas; Thoms, Matthias; Barrio-Garcia, Clara; Cheng, Jingdong; Ismail, Sherif; Ahmed, Yasar Luqman; Bange, Gert; Kressler, Dieter; Berninghausen, Otto; Sinning, Irmgard; Hurt, Ed and Beckmann, Roland (2017): Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes. In: Cell, Vol. 171, No. 7: pp. 1599-1610

Kemter, Elisabeth; Fröhlich, Thomas; Arnold, Georg J.; Wolf, Eckhard and Wanke, Rüdiger (2017): Mitochondrial Dysregulation Secondary to Endoplasmic Reticulum Stress in Autosomal Dominant Tubulointerstitial Kidney Disease - UMOD (ADTKD-UMOD). In: Scientific Reports, Vol. 7, 42970: pp. 1-13 [PDF, 6MB]

Khmelinskaia, A.; Engel, M. and Schwille, P. (2017): Design of a switchable DNA origami structure for shaping lipid membranes. In: European Biophysics Journal With Biophysics Letters, Vol. 46: S122-S122

Kim-Hellmuth, Sarah; Bechheim, Matthias; Pütz, Benno; Mohammadi, Pejman; Nedelec, Yohann; Giangreco, Nicholas; Becker, Jessica; Kaiser, Vera; Fricker, Nadine; Beier, Esther; Boor, Peter; Castel, Stephane E.; Nöthen, Markus M.; Barreiro, Luis B.; Pickrell, Joseph K.; Müller-Myhsok, Bertram; Lappalainen, Tuuli; Schumacher, Johannes and Hornung, Veit (2017): Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations. In: Nature Communications, Vol. 8 [PDF, 1MB]

Kremer, Laura S.; Bader, Daniel M.; Mertes, Christian; Kopajtich, Robert; Pichler, Garwin; Iuso, Arcangela; Haack, Tobias B.; Graf, Elisabeth; Schwarzmayr, Thomas; Terrile, Caterina; Konarikova, Eliska; Repp, Birgit; Kastenmüller, Gabi; Adamski, Jerzy; Lichtner, Peter; Leonhardt, Christoph; Funalot, Benoit; Donati, Alice; Tiranti, Valeria; Lombes, Anne; Jardel, Claude; Glaeser, Dieter; Taylor, Robert W.; Ghezzi, Daniele; Mayr, Johannes A.; Rötig, Agnes; Freisinger, Peter; Distelmaier, Felix; Strom, Tim M.; Meitinger, Thomas; Gagneur, Julien and Prokisch, Holger (2017): Genetic diagnosis of Mendelian disorders via RNA sequencing. In: Nature Communications, Vol. 8, 15824 [PDF, 1MB]

Kremer, Malte C.; Jung, Christophe; Batelli, Sara; Rubin, Gerald M. and Gaul, Ulrike (2017): The Glia of the Adult Drosophila Nervous System. In: Glia, Vol. 65, No. 4: pp. 606-638

Kuang, Zheng; Böke, Jef D. and Canzar, Stefan (2017): The dynamic landscape of fission yeast meiosis alternative-splice isoforms. In: Genome Research, Vol. 27, No. 1: pp. 145-156

Kunzelmann, Stefan and Förstemann, Klaus (2017): Reversible perturbations of gene regulation after genome editing in Drosophila cells.
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Kurz, S.; Janas, M. K.; Schneider, A.; Lohr, K.; Wettmarshausen, J.; Perocchi, F.; Knolle, P. A. and Wohlleber, D. (2017): Linking TNF receptor signaling in virus-infected hepatocytes to cell death for immune control of liver infection. In: European Journal of Immunology, Vol. 47: p. 186

Lavagi, I.; Krebs, S.; Simmet, K.; Zakhartchenko, V.; Wolf, E. and Blum, H. (2017): Single-cell RNA sequencing of bovine Day 2 and Day 3 embryos reveals developmental heterogeneity and early differentiation events. In: Reproduction in Domestic Animals, Vol. 52: pp. 31-32

Leoni, Gabriele; Poli, Andrea de; Mardirossian, Mario; Gambato, Stefano; Florian, Fiorella; Venier, Paola; Wilson, Daniel N.; Tossi, Alessandro; Pallavicini, Alberto and Gerdol, Marco (2017): Myticalins: A Novel Multigenic Family of Linear, Cationic Antimicrobial Peptides from Marine Mussels (Mytilus spp.). In: Marine Drugs, Vol. 15, No. 8, 261 [PDF, 7MB]

Leth, Christoph; Varadharajan, Ashok; Mester, Patrick; Fischaleck, Marlis; Rossmanith, Peter; Schmoll, Friedrich and Fink, Maria (2017): Matrixlysis, an improved sample preparation method for recovery of Mycobacteria from animal tissue material.
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Margos, G.; Hepner, S.; Mang, C.; Marosevic, D.; Reynolds, S. E.; Krebs, S.; Sing, A.; Derdakova, M.; Reiter, M. A. and Fingerle, V. (2017): Lost in plasmids: next generation sequencing and the complex genome of the tick-borne pathogen Borrelia burgdorferi. In: BMC Genomics 18:422 [PDF, 1MB]

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Medugorac, Ivica; Graf, Alexander; Grohs, Cecile; Rothammer, Sophie; Zagdsuren, Yondon; Gladyr, Elena; Zinovieva, Natalia; Barbieri, Johanna; Seichter, Doris; Russ, Ingolf; Eggen, Andre; Hellenthal, Garrett; Brem, Gottfried; Blum, Helmut; Krebs, Stefan and Capitan, Aurélien (2017): Whole-genome analysis of introgressive hybridization and characterization of the bovine legacy of Mongolian yaks. In: Nature Genetics, Vol. 49, No. 3: pp. 470-475

Merk, Karin; Breinig, Marco; Böttcher, Romy; Krebs, Stefan; Blum, Helmut; Boutros, Michael and Förstemann, Klaus (2017): Splicing stimulates siRNA formation at Drosophila DNA double-strand breaks.
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Meyer, K.; Fröhlich, T.; Kösters, M.; Riedel, E.; Fritz, S.; Salvetti, P.; Lonergan, P.; Wolf, E. and Arnold, G. (2017): Impact of metabolic status and genetic merit for fertility on proteomic composition of bovine oviduct fluid. In: Reproduction in Domestic Animals, Vol. 52: p. 36

Mezzadra, Riccardo; Sun, Chong; Jae, Lucas T.; Gomez-Eerland, Raquel; Vries, Evert de; Wu, Wei; Logtenberg, Meike E. W.; Slagter, Maarten; Rozeman, Elisa A.; Hofland, Ingrid; Broeks, Annegien; Horlings, Hugo M.; Wessels, Lodewyk F. A.; Blank, Christian U.; Xiao, Yanling; Heck, Albert J. R.; Borst, Jannie; Brummelkamp, Thijn R. and Schumacher, Ton N. M. (2017): Identification of CMTM6 and CMTM4 as PD-L1 protein regulators. In: Nature, Vol. 549, No. 7670: pp. 106-110

Michel, Margaux; Demel, Carina; Zacher, Benedikt; Schwalb, Björn; Krebs, Stefan; Blum, Helmut; Gagneur, Julien and Cramer, Patrick (2017): TT-seq captures enhancer landscapes immediately after T-cell stimulation. In: Molecular Systems Biology, Vol. 13, No. 3, 920

Mosalaganti, Shyamal; Keller, Jenny; Altenfeld, Anika; Winzker, Michael; Rombaut, Pascaline; Saur, Michael; Petrovic, Arsen; Wehenkel, Annemarie; Wohlgemuth, Sabine; Müller, Franziska; Maffini, Stefano; Bange, Tanja; Herzog, Franz

; Waldmann, Herbert; Raunser, Stefan and Musacchio, Andrea (2017): Structure of the RZZ complex and molecular basis of its interaction with Spindly. In: Journal of Cell Biology, Vol. 216, No. 4: pp. 961-981

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Natchiar, S. Kundhavai; Myasnikov, Alexander G.; Kratzat, Hanna; Hazemann, Isabelle and Klaholz, Bruno P. (2017): Visualization of chemical modifications in the human 80S ribosome structure. In: Nature, Vol. 551, No. 7681: pp. 472-477

Nilsson, Ola B.; Nickson, Adrian A.; Hollins, Jeffrey J.; Wickles, Stephan; Steward, Annette; Beckmann, Roland; Heijne, Gunnar von and Clarke, Jane (2017): Cotranslational folding of spectrin domains via partially structured states. In: Nature Structural & Molecular Biology, Vol. 24, No. 3: pp. 221-225

Nynca, Joanna; Arnold, Georg; Fröhlich, Thomas and Ciereszko, Andrzej (2017): Proteomic identification of rainbow trout blood plasma proteins and their relationship to seminal plasma proteins. In: Proteomics, Vol. 17, No. 11, 1600460

Pachzelt, L.; Krupka, C.; Kischel, R.; Kufer, P.; Köhnke, T.; Polzer, H.; Spiekermann, K.; Hiddemann, W. and Subklewe, M. (2017): Costimulation Increases Intracellular Signalling In Bite (R) Antibody Construct Mediated T-Cell Activation. In: Haematologica, Vol. 102: p. 361

Perocchi, F. (2017): Systematic identification of MCU modulators by orthogonal interspecies chemical screening. In: Acta Physiologica, Vol. 221: p. 11

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Rettinger, A.; Broeckl, S.; Fink, M.; Prodinger, W. M.; Blum, H.; Krebs, S.; Domogalla, J.; Just, F.; Gellert, S.; Straubinger, R. K. and Büttner, M. (2017): The Region of Difference Four is a Robust Genetic Marker for Subtyping Mycobacteriumcaprae Isolates and is Linked to Spatial Distribution of Three Subtypes. In: Transboundary and Emerging Diseases, Vol. 64, No. 3: pp. 782-792

Rothammer, Sophie; Kunz, Elisabeth; Seichter, Doris; Krebs, Stefan; Wassertheurer, Martina; Fries, Ruedi; Brem, Gottfried and Medugorac, Ivica (2017): Detection of two non-synonymous SNPs in SLC45A2 on BTA20 as candidate causal mutations for oculocutaneous albinism in Braunvieh cattle. In: Genetics Selection Evolution 49:73 [PDF, 1MB]

Sarkar, Anshuk; Thoms, Matthias; Barrio-Garcia, Clara; Thomson, Emma; Flemming, Dirk; Beckmann, Roland and Hurt, Ed (2017): Preribosomes escaping from the nucleus are caught during translation by cytoplasmic quality control. In: Nature Structural & Molecular Biology, Vol. 24, No. 12: pp. 1107-1115

Schmid, N.; Flenkenthaler, F.; Dietrich, K.; Fröhlich, T.; Arnold, G. J.; Behr, R. and Mayerhofer, A. (2017): A non-human primate model for the study of testicular peritubular cells. In: Reproduction in Domestic Animals, Vol. 52: p. 47

Schneider, Constanze; Oellerich, Thomas; Baldauf, Hanna-Mari; Schwarz, Sarah-Marie; Thomas, Dominique; Flick, Robert; Bohnenberger, Hanibal; Kaderali, Lars; Stegmann, Lena; Cremer, Anjali; Martin, Margarethe; Lohmeyer, Julian; Michaelis, Martin; Hornung, Veit; Schliemann, Christoph; Berdel, Wolfgang E.; Hartmann, Wolfgang; Wardelmann, Eva; Comoglio, Federico; Hansmann, Martin-Leo; Yakunin, Alexander F.; Geisslinger, Gerd; Stroebel, Philipp; Ferreiros, Nerea; Serve, Hubert; Keppler, Oliver T. and Cinatl, Jindrich (2017): SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia. In: Nature Medicine, Vol. 23, No. 2: pp. 250-255

Schrode, Pius; Huter, Paul; Clementi, Nina and Erlacher, Matthias (2017): Atomic mutagenesis at the ribosomal decoding site. In: Rna Biology, Vol. 14, No. 1: pp. 104-112

Schwabe, Tina; Li, Xiaoling and Gaul, Ulrike (2017): Dynamic analysis of the mesenchymal-epithelial transition of blood-brain barrier forming glia in Drosophila. In: Biology Open, Vol. 6, No. 2: pp. 232-243 [PDF, 6MB]

Silva, P.; Neumann, M.; Schroeder, M. P.; Vosberg, S.; Schlee, C.; Isaakidis, K.; Ortiz-Tanchez, J.; Fransecky, L. R.; Hartung, T.; Türkmen, S.; Graf, A.; Krebs, S.; Blum, H.; Müller-Tidow, C.; Thiede, C.; Ehninger, G.; Serve, H.; Hecht, J.; Berdel, W. E.; Greif, P. A.; Röllig, C. and Baldus, C. D. (2017): Acute myeloid leukemia in the elderly is characterized by a distinct genetic and epigenetic landscape. In: Leukemia, Vol. 31, No. 7: pp. 1640-1644

Simintiras, Constantine A.; Froehlich, Thomas; Sathyapalan, Thozhukat; Arnold, Georg J.; Ulbrich, Susanne E.; Leese, Henry J. and Sturmey, Roger G. (2017): Modelling aspects of oviduct fluid formation in vitro. In: Reproduction, Vol. 153, No. 1: pp. 23-33

Singh, Hari R.; Nardozza, Aurelio P.; Möller, Ingvar R.; Knobloch, Gunnar; Kistemaker, Hans A. V.; Hassler, Markus; Harrer, Nadine; Blessing, Charlotte; Eustermann, Sebastian; Kotthoff, Christiane; Huet, Sebastien; Müller-Planitz, Felix; Filippov, Dmitri V.; Timinszky, Gyula; Rand, Kasper D. and Ladurner, Andreas G. (2017): A Poly-ADP-Ribose Trigger Releases the Auto-Inhibition of a Chromatin Remodeling Oncogene. In: Molecular Cell, Vol. 68, No. 5: pp. 860-871

Slowinska, M.; Nynca, J.; Arnold, G. J.; Fröhlich, T.; Jankowski, J.; Kozlowski, K.; Mostek, A. and Ciereszko, A. (2017): Proteomic identification of turkey (Meleagris gallopavo) seminal plasma proteins. In: Poultry Science, Vol. 96, No. 9: pp. 3422-3435

Solis-Mezarino, Victor and Herzog, Franz

(2017): compleXView: a server for the interpretation of protein abundance and connectivity information to identify protein complexes. In: Nucleic acids research, Vol. 45, No. W1: W276-W284 [PDF, 4MB]

Solis-Mezarino, Victor and Herzog, Franz

(2017): compleXView: a server for the interpretation of protein abundance and connectivity information to identify protein complexes. In: Nucleic Acids Research, Vol. 45, No. W1: W276-W284

Stricker, Georg; Engelhardt, Alexander; Schulz, Daniel; Schmid, Matthias; Tresch, Achim and Gagneur, Julien (2017): GenoGAM: genome-wide generalized additive models for ChIP-Seq analysis. In: Bioinformatics, Vol. 33, No. 15: pp. 2258-2265

Sturm, Miriam; Cheng, Jingdong; Baßler, Jochen; Beckmann, Roland and Hurt, Ed (2017): Interdependent action of KH domain proteins Krr1 and Dim2 drive the 40S platform assembly. In: Nature Communications, Vol. 8, 2213 [PDF, 3MB]

Su, Ting; Cheng, Jingdong; Sohmen, Daniel; Hedman, Rickard; Berninghausen, Otto; Heijne, Gunnar von; Wilson, Daniel N. and Beckmann, Roland (2017): The force-sensing peptide VemP employs extreme compaction and secondary structure formation to induce ribosomal stalling. In: Elife, Vol. 6, e25642 [PDF, 7MB]

Tants, Jan-Niklas; Fesser, Stephanie; Kern, Thomas; Stehle, Ralf; Geerlof, Arie; Wunderlich, Christoph; Jün, Michael; Hartlmüller, Christoph; Böttcher, Romy; Kunzelmann, Stefan; Lange, Oliver; Kreutz, Christoph; Förstemann, Klaus and Sattler, Michael (2017): Molecular basis for asymmetry sensing of siRNAs by the Drosophila Loqs-PD/Dcr-2 complex in RNA interference. In: Nucleic Acids Research, Vol. 45, No. 21: pp. 12536-12550

Tkatch, Tatiana; Greotti, Elisa; Baranauskas, Gytis; Pendin, Diana; Roy, Soumitra; Nita, Luliaoana I.; Wettmarshausen, Jennifer; Prigge, Matthias; Yizhar, Ofer; Shirihai, Orian S.; Fishman, Daniel; Hershfinkel, Michal; Fleidervish, Ilya A.; Perocchi, Fabiana; Pozzan, Tullio and Sekler, Israel (2017): Optogenetic control of mitochondrial metabolism and Ca2+ signaling by mitochondria-targeted opsins. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, No. 26, E5167-E5176

Vogel, Anna-Lena; Knier, Benjamin; Lammens, Katja; Kalluri, Sudhakar Reddy; Kuhlmann, Tanja; Bennett, Jeffrey L. and Korn, Thomas (2017): Deletional tolerance prevents AQP4-directed autoimmunity in mice. In: European Journal of Immunology, Vol. 47, No. 3: pp. 458-469

Vosberg, S.; Hartmann, L.; Metzeler, K. H.; Schumacher, D.; Pastore, F.; Bräundl, K.; Zellmeier, E.; Ksienzyk, B.; Konstandin, N. P.; Schneider, S.; Graf, A.; Krebs, S.; Blum, H.; Neumann, M.; Baldus, C. D.; Bohlander, S. K.; Wolf, S.; Hiddemann, W.; Spiekermann, K. and Greif, P. A. (2017): Evolutionary Patterns of Cytogenetically Normal Acute Myeloid Leukemia Correlate with Time to Relapse. In: Annals of Hematology, Vol. 96: S55-S55

Wei, Hai; Yan, Bo; Gagneur, Julien and Conradt, Barbara (2017): Caenorhabditis elegans CES-1 Snail Represses pig-1 MELK Expression To Control Asymmetric Cell Division. In: Genetics, Vol. 206, No. 4: pp. 2069-2084

Woischke, Christine; Schaaf, Christian W.; Yang, Hui-Min; Vieth, Michael; Veits, Lothar; Geddert, Helene; Märkl, Bruno; Stömmer, Peter; Schaeffer, David F.; Frölich, Matthias; Blum, Helmut; Vosberg, Sebastian; Greif, Philipp A.; Jung, Andreas; Kirchner, Thomas and Horst, David (2017): In-depth mutational analyses of colorectal neuroendocrine carcinomas with adenoma or adenocarcinoma components. In: Modern Pathology, Vol. 30, No. 1: pp. 95-103

Wratil, Paul R. and Horstkorte, Rüdiger (2017): Metabolic Glycoengineering of Sialic Acid Using N-acyl-modified Mannosamines. In: Jove-Journal of Visualized Experiments, No. 129, e55746

Yamashita, Yui; Takamatsu, Seidai; Glasbrenner, Michael; Becker, Thomas; Naito, Satoshi and Beckmann, Roland (2017): Sucrose sensing through nascent peptide-meditated ribosome stalling at the stop codon of Arabidopsis bZIP11 uORF2. In: Febs Letters, Vol. 591, No. 9: pp. 1266-1277

Ye, Qiaozhen; Kim, Dong Hyun; Dereli, Ihsan; Rosenberg, Scott C.; Hagemann, Götz; Herzog, Franz

; Toth, Attila; Cleveland, Don W. and Corbett, Kevin D. (2017): The AAA plus ATPase TRIP13 remodels HORMA domains through N-terminal engagement and unfolding. In: Embo Journal, Vol. 36, No. 16: pp. 2419-2434

Yi, Chun-Xia; Walter, Marc; Gao, Yuanqing; Pitra, Soledad; Legutko, Beata; Kaelin, Stefanie; Layritz, Clarita; Garcia-Caceres, Cristina; Bielohuby, Maximilian; Bidlingmaier, Martin; Woods, Stephen C.; Ghanem, Alexander; Conzelmann, Karl-Klaus; Stern, Javier E.; Jastroch, Martin and Tschöp, Matthias H. (2017): TNF alpha drives mitochondrial stress in POMC neurons in obesity. In: Nature Communications, Vol. 8, 15143 [PDF, 1MB]

Yoon, Ki-Jun; Ringeling, Francisca Rojas; Vissers, Caroline; Jacob, Fadi; Pokrass, Michael; Jimenez-Cyrus, Dennisse; Su, Yijing; Kim, Nam-Shik; Zhu, Yunhua; Zheng, Lily; Kim, Sunghan; Wang, Xinyuan; Dore, Louis C.; Jin, Peng; Regot, Sergi; Zhuang, Xiaoxi; Canzar, Stefan; He, Chuan; Ming, Guo-li and Song, Hongjun (2017): Temporal Control of Mammalian Cortical Neurogenesis by m(6)A Methylation. In: Cell, Vol. 171, No. 4: pp. 877-889

Zacher, Benedikt; Michel, Margaux; Schwalb, Björn; Cramer, Patrick; Tresch, Achim and Gagneur, Julien (2017): Accurate Promoter and Enhancer Identification in 127 ENCODE and Roadmap Epigenomics Cell Types and Tissues by GenoSTAN.
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2016

Albl, Barbara; Haesner, Serena; Braun-Reichhart, Christina; Streckel, Elisabeth; Renner, Simone; Seeliger, Frank; Wolf, Eckhard; Wanke, Rüdiger and Blutke, Andreas (2016): Tissue Sampling Guides for Porcine Biomedical Models. In: Toxicologic Pathology, Vol. 44, No. 3: pp. 414-420 [PDF, 142kB]

Altunkaya, Gülsah Pekgöz; Malvezzi, Francesca; Demianova, Zuzana; Zimniak, Tomasz; Litos, Gabriele; Weissmann, Florian; Mechtler, Karl; Herzog, Franz and Westermann, Stefan (2016): CCAN Assembly Configures Composite Binding Interfaces to Promote Cross-Linking of Ndc80 Complexes at the Kinetochore. In: Current Biology, Vol. 26, No. 17: pp. 2370-2378

Arenz, Stefan; Juette, Manuel F.; Graf, Michael; Nguyen, Fabian; Huter, Paul; Polikanov, Yury S.; Blanchard, Scott C. and Wilson, Daniel N. (2016): Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 27: pp. 7527-7532

Arenz, Stefan and Wilson, Daniel N. (2016): Blast from the Past: Reassessing Forgotten Translation Inhibitors, Antibiotic Selectivity, and Resistance Mechanisms to Aid Drug Development. In: Molecular Cell, Vol. 61, No. 1: pp. 3-14

Barford, David and Hopfner, Karl-Peter (2016): Editorial overview: Macromolecular machines and assemblies. In: Current Opinion in Structural Biology, Vol. 37: VI-VIII

Barrio-Garcia, Clara; Thoms, Matthias; Flemming, Dirk; Katerl, Lukas; Berninghausenl, Otto; Baßler, Jochen; Beckmann, Roland and Hurt, Ed (2016): Architecture of the Rix1-Rea1 checkpoint machinery during pre-60S-ribosome remodeling. In: Nature Structural & Molecular Biology, Vol. 23, No. 1: pp. 37-44

Bassani-Sternberg, Michal; Bräunlein, Eva; Klar, Richard; Engleitner, Thomas; Sinitcyn, Pavel; Audehm, Stefan; Straub, Melanie; Weber, Julia; Slotta-Huspenina, Julia; Specht, Katja; Martignoni, Marc E.; Werner, Angelika; Hein, Rüdiger; Busch, Dirk H.; Peschel, Christian; Rad, Roland; Cox, Jürgen; Mann, Matthias and Krackhardt, Angela M. (2016): Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry. In: Nature Communications, Vol. 7, 13404 [PDF, 1MB]

Bauernfeind, Franz; Niepmann, Sven; Knolle, Percy A. and Hornung, Veit (2016): Aging-Associated TNF Production Primes Inflammasome Activation and NLRP3-Related Metabolic Disturbances. In: Journal of Immunology, Vol. 197, No. 7: pp. 2900-2908

Bernecky, Carrie; Herzog, Franz; Baumeister, Wolfgang; Plitzko, Jürgen M. and Cramer, Patrick (2016): Structure of transcribing mammalian RNA polymerase II. In: Nature, Vol. 529, No. 7587: pp. 551-554

Blutke, Andreas; Schneider, Marlon R.; Wolf, Eckhard and Wanke, Rüdiger (2016): Growth hormone (GH)-transgenic insulin-like growth factor 1 (IGF1)-deficient mice allow dissociation of excess GH and IGF1 effects on glomerular and tubular growth. In: Physiological Reports, Vol. 4, No. 5, e12709 [PDF, 3MB]

Bock, Lars V.; Arenz, Stefan; Wilson, Daniel N.; Grubmüller, Helmut and Vaiana, Andrea C. (2016): ErmBL Translation on the Ribosome in the Presence of Erythromycin is Stalled by Inhibition of Peptide Bond Formation. In: Biophysical Journal, Vol. 110, No. 3: 234A-234A

Boorn, Jasper G. van den; Jakobs, Christopher; Hagen, Christian; Renn, Marcel; Luiten, Rosalie M.; Melief, Cornelis J. M.; Tüting, Thomas; Garbi, Natalio; Hartmann, Gunther and Hornung, Veit (2016): Inflammasome-Dependent Induction of Adaptive NK Cell Memory. In: Immunity, Vol. 44, No. 6: pp. 1406-1421

Bullock, Joshua Matthew Allen; Schwab, Jannik; Thalassinos, Konstantinos and Topf, Maya (2016): The Importance of Non-accessible Crosslinks and Solvent Accessible Surface Distance in Modeling Proteins with Restraints From Crosslinking Mass Spectrometry. In: Molecular & Cellular Proteomics, Vol. 15, No. 7: pp. 2491-2500

Chagin, V. O.; Casas-Delucchi, C. S.; Reinhart, M.; Schermelleh, L.; Markaki, Y.; Maiser, A.; Bolius, J. J.; Bensimon, A.; Fillies, M.; Domaing, P.; Rozanov, Y. M.; Leonhardt, H. and Cardoso, M. C. (2016): 4D Visualization of replication foci in mammalian cells corresponding to individual replicons. In: Nature Communications, Vol. 7, 11231 [PDF, 2MB]

Dahlhoff, Maik; Fröhlich, Thomas; Arnold, Georg J.; Zouboulis, Christos C. and Schneider, Marlon R. (2016): LC-MS/MS analysis reveals a broad functional spectrum of proteins in the secretome of sebocytes. In: Experimental Dermatology, Vol. 25, No. 1: pp. 66-67

Deeg, Cornelia A.; Uhl, Patrizia; Amann, Barbara; Blutke, Andreas; Renner, Simone; Hirmer, Sieglinde; Merl-Pham, Juliane; Sekundo, Walter; Wanke, Ruediger; Wolf, Eckhard and Hauck, Stefanie M. (2016): The INSC94Y transgenic pig: a novel model for diabetic retinopathy with macular edema. In: Investigative Ophthalmology & Visual Science, Vol. 57, No. 12

Deeng, J.; Chan, K. Y.; Sluis, E. O. van der; Berninghausen, O.; Han, W.; Gumbart, J.; Schulten, K.; Beatrix, B. and Beckmann, R. (2016): Dynamic Behavior of Trigger Factor on the Ribosome. In: Journal of Molecular Biology, Vol. 428, No. 18: pp. 3588-3602

Diener, Susanne; Bayer, Sieglinde; Sabrautzki, Sibylle; Wieland, Thomas; Mentrup, Birgit; Przemeck, Gerhard K. H.; Rathkolb, Birgit; Graf, Elisabeth; Hans, Wolfgang; Fuchs, Helmut; Horsch, Marion; Schwarzmayr, Thomas; Wolf, Eckhard; Klopocki, Eva; Jakob, Franz; Strom, Tim M.; Hrabě de Angelis, Martin and Lorenz-Depiereux, Bettina (2016): Exome sequencing identifies a nonsense mutation in Fam46a associated with bone abnormalities in a new mouse model for skeletal dysplasia. In: Mammalian Genome, Vol. 27, No. 3-4: pp. 111-121

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Siebert, Matthias and Söding, Johannes (2016): Bayesian Markov models consistently outperform PWMs at predicting motifs in nucleotide sequences. In: Nucleic Acids Research, Vol. 44, No. 13: pp. 6055-6069 [PDF, 4MB]

Stahl, Evi; Praetorius, Florian; Mann, Carina C. de Oliveira; Hopfner, Karl-Peter and Dietz, Hendrik (2016): Impact of Heterogeneity and Lattice Bond Strength on DNA Triangle Crystal Growth. In: Acs Nano, Vol. 10, No. 10: pp. 9156-9164

Steward, Annette; Nilsson, Ola B.; Nickson, Adrian A.; Hollins, Jeffrey J.; Wickles, Stephan; Marsden, Andrew; Mendonca, Carolina; Beckmann, Roland; Heijne, Gunnar von and Clarke, Jane (2016): Cotranslational folding studies of spectrin and Ig-like domains show folding occurs close to the ribosome. In: Protein Science, Vol. 25: pp. 107-108

Stützer, Alexandra; Liokatis, Stamatios; Kiesel, Anja; Schwarzer, Dirk; Sprangers, Remco; Söding, Johannes; Selenko, Philipp and Fischle, Wolfgang (2016): Modulations of DNA Contacts by Linker Histones and Post-translational Modifications Determine the Mobility and Modifiability of Nucleosomal H3 Tails. In: Molecular Cell, Vol. 61, No. 2: pp. 247-259

Słowińska, M.; Nynca, J.; Arnold, G. J.; Fröhlich, T. and Ciereszko, A. (2016): Proteomic identification of turkey (Meleagris gallopavo) seminal plasma proteins. In: Animal Reproduction Science, Vol. 169: p. 98

Tanaka, Mayuki; Sotta, Naoyuki; Yamazumi, Yusuke; Yamashita, Yui; Miwa, Kyoko; Murota, Katsunori; Chiba, Yukako; Hirai, Masami Yokota; Akiyama, Tetsu; Onouchi, Hitoshi; Naito, Satoshi and Fujiwara, Toru (2016): The Minimum Open Reading Frame, AUG-Stop, Induces Boron-Dependent Ribosome Stalling and mRNA Degradation. In: Plant Cell, Vol. 28, No. 11: pp. 2830-2849

Trapphoff, T.; Heiligentag, M.; Dankert, D.; Demond, H.; Deutsch, D.; Fröhlich, T.; Arnold, G. J.; Grümmer, R.; Horsthemke, B. and Eichenlaub-Ritter, U. (2016): Postovulatory aging affects dynamics of mRNA, expression and localization of maternal effect proteins, spindle integrity and pericentromeric proteins in mouse oocytes. In: Human Reproduction, Vol. 31, No. 1: pp. 133-149

Trapphoff, Tom; Heiligentag, Martyna; Simon, Jenny; Staubach, Nora; Seidel, Thorsten; Otte, Kathrin; Fröhlich, Thomas; Arnold, Georg J. and Eichenlaub-Ritter, Ursula (2016): Improved cryotolerance and developmental potential of in vitro and in vivo matured mouse oocytes by supplementing with a glutathione donor prior to vitrification. In: Molecular Human Reproduction, Vol. 22, No. 12: pp. 867-881

Vos, Seychelle M.; Pöllmann, David; Caizzi, Livia; Hofmann, Katharina B.; Rombaut, Pascaline; Zimniak, Tomasz; Herzog, Franz and Cramer, Patrick (2016): Architecture and RNA binding of the human negative elongation factor. In: eLife, Vol. 5, e14981 [PDF, 6MB]

Vos, Seychelle M.; Pöllmann, David; Caizzi, Livia; Hofmann, Katharina B.; Rombaut, Pascaline; Zimniak, Tomasz; Herzog, Franz

and Cramer, Patrick (2016): Architecture and RNA binding of the human negative elongation factor. In: eLife, Vol. 5, e14981 [PDF, 11MB]

Wales, Pauline; Schuberth, Christian E.; Aufschnaiter, Roland; Fels, Johannes; García-Aguilar, Ireth; Janning, Annette; Dlugos, Christopher P.; Schäfer-Herte, Marco; Klingner, Christoph; Wälte, Mike; Kuhlmann, Julian; Menis, Ekaterina; Kang, Laura Hockaday; Maier, Kerstin C.; Hou, Wenya; Russo, Antonella; Higgs, Henry N.; Pavenstädt, Hermann; Vogl, Thomas; Roth, Johannes; Qualmann, Britta; Kessels, Michael M.; Martin, Dietmar E.; Mulder, Bela and Wedlich-Söldner, Roland (2016): Calcium-mediated actin reset (CaAR) mediates acute cell adaptations. In: eLife, Vol. 5, e19850 [PDF, 4MB]

Weir, John R.; Faesen, Alex C.; Klare, Kerstin; Petrovic, Arsen; Basilico, Federica; Fischböck, Josef; Pentakota, Satyakrishna; Keller, Jenny; Pesenti, Marion E.; Pan, Dongqing; Vogt, Doro; Wohlgemuth, Sabine; Herzog, Franz

and Musacchio, Andrea (2016): Insights from biochemical reconstitution into the architecture of human kinetochores. In: Nature, Vol. 537, No. 7619: pp. 249-253 [PDF, 7MB]

and Musacchio, Andrea (2016): Insights from biochemical reconstitution into the architecture of human kinetochores. In: Nature, Vol. 537, 7619: pp. 249-253

Wilson, Daniel; Spahn, Christian and Yusupov, Marat (2016): Ribosomes Structure and Mechanisms in Regulation of Protein Synthesis Part I. In: Journal of Molecular Biology, Vol. 428, No. 10: p. 2133

Wilson, Daniel; Spahn, Christian and Yusupov, Marat (2016): Special Issue: Ribosomes Structure and Mechanisms in Regulation of Protein Synthesis (II). In: Journal of Molecular Biology, Vol. 428, No. 18: p. 3557

Wilson, Daniel N. (2016): The ABC of Ribosome-Related Antibiotic Resistance. In: Mbio, Vol. 7, No. 3, e00598-16

Wilson, Daniel N.; Arenz, Stefan and Beckmann, Roland (2016): Translation regulation via nascent polypeptide-mediated ribosome stalling. In: Current Opinion in Structural Biology, Vol. 37: pp. 123-133

Wilson, Daniel N. and Clark, Patricia L. (2016): Climbing to the peak of nascent-chain knowledge. In: Nature Structural & Molecular Biology, Vol. 23, No. 11: pp. 949-951

Wilson, Daniel N. and Spahn, Christian M. T. (2016): Knud Hermann Nierhaus 1941-2016 OBITUARY. In: Nature Structural & Molecular Biology, Vol. 23, No. 6: pp. 503-504

Wissel, Sebastian; Kieser, Anja; Yasugi, Tetsuo; Duchek, Peter; Roitinger, Elisabeth; Gokcezade, Joseph; Steinmann, Victoria; Gaul, Ulrike; Mechtler, Karl; Förstemann, Klaus; Knoblich, Jürgen A. and Neumüller, Ralph A. (2016): A Combination of CRISPR/Cas9 and Standardized RNAi as a Versatile Platform for the Characterization of Gene Function. In: G3 - Genes Genomes Genetics, Vol. 6, No. 8: pp. 2467-2478 [PDF, 3MB]

Xu, Shuting; Ducroux, Aurelie; Ponnurangam, Aparna; Franz, Sergej; Vieyres, Gabrielle; Müsken, Mathias; Zillinger, Thomas; Malassa, Angelina; Ewald, Ellen; Hornung, Veit; Barchet, Winfried; Häussler, Susanne; Pietschmann, Thomas and Goffinet, Christine (2016): cGAMP transfers intercellularly via HIV-1 Env-mediated cell-cell fusion sites and triggers an innate immune response in primary target cells. Frontiers of Retrovirology Conference 2016, Erlangen, Germany, Montag, 12. September bis Mittwoch, 14. September 2016. In: Retrovirology. Vol. 13. BioMed Central. [PDF, 3MB]

Xu, Shuting; Ducroux, Aurélie; Ponnurangam, Aparna; Vieyres, Gabrielle; Franz, Sergej; Müsken, Mathias; Zillinger, Thomas; Malassa, Angelina; Ewald, Ellen; Hornung, Veit; Barchet, Winfried; Häussler, Susanne; Pietschmann, Thomas and Goffinet, Christine (2016): cGAS-Mediated Innate Immunity Spreads Intercellularly through HIV-1 Env-Induced Membrane Fusion Sites. In: Cell Host & Microbe, Vol. 20, No. 4: pp. 443-457

Yamamoto, Hiroshi; Wittek, Daniela; Gupta, Romi; Qin, Bo; Ueda, Takuya; Krause, Roland; Yamamoto, Kaori; Albrecht, Renate; Pech, Markus and Nierhaus, Knud H. (2016): 70S-scanning initiation is a novel and frequent initiation mode of ribosomal translation in bacteria. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 9, E1180-E1189

Zocco, Manuel; Marasovic, Mirela; Pisacane, Paola; Bilokapic, Silvija and Halic, Mario (2016): The Chp1 chromodomain binds the H3K9me tail and the nucleosome core to assemble heterochromatin. In: Cell Discovery, Vol. 2, UNSP 16004

2015

Banerjee, Rupa; Gladkova, Christina; Mapa, Koyeli; Witte, Gregor and Mokranjac, Dejana (2015): Protein translocation channel of mitochondrial inner membrane and matrix-exposed import motor communicate via two-domain coupling protein. In: eLife, Vol. 4, e11897 [PDF, 2MB]

Butryn, Agata; Schuller, Jan M.; Stoehr, Gabriele; Runge-Wollmann, Petra; Förster, Friedrich; Auble, David T. and Hopfner, Karl-Peter (2015): Structural basis for recognition and remodeling of the TBP:DNA:NC2 complex by Mot1. In: eLife, Vol. 4, e07432 [PDF, 3MB]

Grimm, Maximilian; Zimniak, Tomasz; Kahraman, Abdullah and Herzog, Franz (2015): xVis: a web server for the schematic visualization and interpretation of crosslink-derived spatial restraints. In: Nucleic Acids Research, Vol. 43, No. W1: W362-W369 [PDF, 3MB]

Kock, Malte; Nunes, Maria M.; Hemann, Matthias; Kube, Sebastian; Dohmen, R. Jürgen; Herzog, Franz; Ramos, Paula C. and Wendler, Petra (2015): Proteasome assembly from 15S precursors involves major conformational changes and recycling of the Pba1-Pba2 chaperone. In: Nature Communications, Vol. 6, 6123 [PDF, 2MB]

Laessig, Charlotte; Matheisl, Sarah; Sparrer, Konstantin M. J.; Mann, Carina C. de Oliveira; Moldt, Manuela; Patel, Jenish R.; Goldeck, Marion; Hartmann, Gunther; Garcia-Sastre, Adolfo; Hornung, Veit; Conzelmann, Karl-Klaus; Beckmann, Roland and Hopfner, Karl-Peter (2015): ATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA. In: eLife, Vol. 4, e10859 [PDF, 2MB]

Liu, Verena; Dietrich, Alexandra; Kasparek, Michael S.; Benhaqi, Petra; Schneider, Marlon R.; Schemann, Michael; Seeliger, Hendrik and Kreis, Martin E. (2015): Extrinsic intestinal denervation modulates tumor development in the small intestine of Apc(Min/+) mice. In: Journal of Experimental & Clinical Cancer Research 34:39 [PDF, 918kB]

Matheisl, Sarah; Berninghausen, Otto; Becker, Thomas and Beckmann, Roland (2015): Structure of a human translation termination complex. In: Nucleic Acids Research, Vol. 43, No. 18: pp. 8615-8626 [PDF, 6MB]

Nilsson, Ola B.; Hedman, Rickard; Marino, Jacopo; Wickles, Stephan; Bischoff, Lukas; Johansson, Magnus; Müller-Lucks, Annika; Trovato, Fabio; Puglisi, Joseph D.; O'Brien, Edward P.; Beckmann, Roland and Heijne, Gunnar von (2015): Cotranslational Protein Folding inside the Ribosome Exit Tunnel. In: Cell Reports, Vol. 12, No. 10: pp. 1533-1540 [PDF, 2MB]

Pfeffer, Stefan; Burbaum, Laura; Unverdorben, Pia; Pech, Markus; Chen, Yuxiang; Zimmermann, Richard; Beckmann, Roland and Foerster, Friedrich (2015): Structure of the native Sec61 protein-conducting channel. In: Nature Communications, Vol. 6, 8403 [PDF, 1MB]

Seifert, Florian; Lammens, Katja and Hopfner, Karl-Peter (22. May 2015): Structure of the catalytic domain of Mre11 from Chaetomium thermophilum. In: Acta Crystallographica Section F : Structural Biology Communications, Vol. 71, No. 6: pp. 752-757 [PDF, 1MB]

Sluis, Eli O. van der; Bauerschmitt, Heike; Becker, Thomas; Mielke, Thorsten; Frauenfeld, Jens; Berninghausen, Otto; Neupert, Walter; Herrmann, Johannes M. and Beckmann, Roland (2015): Parallel Structural Evolution of Mitochondrial Ribosomes and OXPHOS Complexes. In: Genome Biology and Evolution, Vol. 7, No. 5: pp. 1235-1251 [PDF, 1MB]

Sohmen, Daniel; Chiba, Shinobu; Shimokawa-Chiba, Naomi; Innis, C. Axel; Berninghausen, Otto; Beckmann, Roland; Ito, Koreaki and Wilson, Daniel N. (2015): Structure of the Bacillus subtilis 70S ribosome reveals the basis for species-specific stalling. In: Nature Communications, Vol. 6, 6941 [PDF, 2MB]

Verdone, Loredana; La Fortezza, Marco; Ciccarone, Fabio; Caiafa, Paola; Zampieri, Michele and Caserta, Micaela (2015): Poly(ADP-Ribosyl)ation Affects Histone Acetylation and Transcription.
In: PLOS ONE 10(12), e0144287 [PDF, 890kB]

2014

Bischoff, Lukas; Berninghausen, Otto and Beckmann, Roland (2014): Molecular Basis for the Ribosome Functioning as an L-Tryptophan Sensor. In: Cell Reports, Vol. 9, No. 2: pp. 469-475 [PDF, 3MB]

Bischoff, Lukas; Wickles, Stephan; Berninghausen, Otto; Sluis, Eli O. van der and Beckmann, Roland (2014): Visualization of a polytopic membrane protein during SecY-mediated membrane insertion. In: Nature Communications, Vol. 5, 4103 [PDF, 2MB]

Böttcher, Romy; Hollmann, Manuel; Merk, Karin; Nitschko, Volker; Obermaier, Christina; Philippou-Massier, Julia; Wieland, Isabella; Gaul, Ulrike and Förstemann, Klaus (2014): Efficient chromosomal gene modification with CRISPR/cas9 and PCR-based homologous recombination donors in cultured Drosophila cells. In: Nucleic Acids Research, Vol. 42, No. 11, e89

Delsate, Dominique and Ezcurra, Martin D. (2014): The first Early Jurassic (late Hettangian) theropod dinosaur remains from the Grand Duchy of Luxembourg. In: Geologica Belgica, Vol. 17, No. 2: pp. 175-181

Dindar, Gülcin; Anger, Andreas M.; Mehlhorn, Christine; Hake, Sandra B. and Janzen, Christian J. (2014): Structure-guided mutational analysis reveals the functional requirements for product specificity of DOT1 enzymes. In: Nature Communications, Vol. 5, 5313 [PDF, 2MB]

Eser, Philipp; Demel, Carina; Maier, Kerstin C.; Schwalb, Björn; Pirkl, Nicole; Martin, Dietmar E.; Cramer, Patrick and Tresch, Achim (2014): Periodic mRNA synthesis and degradation co-operate during cell cycle gene expression. In: Molecular Systems Biology, Vol. 10, No. 1

Ezcurra, Martin D. (2014): The Osteology of the Basal Archosauromorph Tasmaniosaurus triassicus from the Lower Triassic of Tasmania, Australia.
In: PLOS ONE 9(1), e86864 [PDF, 11MB]

Ezcurra, Martin D.; Scheyer, Torsten M. and Butler, Richard J. (2014): The Origin and Early Evolution of Sauria: Reassessing the Permian Saurian Fossil Record and the Timing of the Crocodile-Lizard Divergence.
In: PLOS ONE 9(2), e89165 [PDF, 5MB]

Ghalei, Homa; Moeller, Holger von; Eppers, Detlef; Sohmen, Daniel; Wilson, Daniel N.; Loll, Bernhard and Wahl, Markus C. (2014): Entrapment of DNA in an intersubunit tunnel system of a single-stranded DNA-binding protein. In: Nucleic Acids Research, Vol. 42, No. 10: pp. 6698-6708

Heger, Klaus; Fierens, Kaat; Vahl, J. Christoph; Aszodi, Attila; Peschke, Katrin; Schenten, Dominik; Hammad, Hamida; Beyaert, Rudi; Saur, Dieter; Loo, Geert van; Roers, Axel; Lambrecht, Bart N.; Kool, Mirjam and Schmidt-Supprian, Marc (2014): A20-Deficient Mast Cells Exacerbate Inflammatory Responses In Vivo.
In: PLOS Biology 12(1), e1001762 [PDF, 2MB]

Hernando, Henar; Islam, Abul B. M. M. K.; Rodriguez-Ubreva, Javier; Forne, Ignasi; Ciudad, Laura; Imhof, Axel; Shannon-Lowe, Claire and Ballestar, Esteban (2014): Epstein-Barr virus-mediated transformation of B cells induces global chromatin changes independent to the acquisition of proliferation. In: Nucleic Acids Research, Vol. 42, No. 1: pp. 249-263

Hirschmann, Wolf D.; Westendorf, Heidrun; Mayer, Andreas; Cannarozzi, Gina; Cramer, Patrick and Jansen, Ralf-Peter (2014): Scp160p is required for translational efficiency of codon-optimized mRNAs in yeast. In: Nucleic Acids Research, Vol. 42, No. 6: pp. 4043-4055 [PDF, 2MB]

Hopfner, Karl-Peter (11. September 2014): ATP puts the brake on DNA double-strand break repair. A new study shows that ATP switches the Mre11-Rad50-Nbs1 repair factor between signaling and processing of DNA ends. In: BioEssays, Vol. 36, No. 12: pp. 1170-1178 [PDF, 837kB]

Karakasili, Eleni; Burkert-Kautzsch, Cornelia; Kieser, Anja and Strässer, Katja (2014): Degradation of DNA damage-independently stalled RNA polymerase II is independent of the E3 ligase Elc1. In: Nucleic Acids Research, Vol. 42, No. 16: pp. 10503-10515 [PDF, 1MB]

Kube, Sebastian; Kapitein, Nicole; Zimniak, Tomasz; Herzog, Franz; Mogk, Axel and Wendler, Petra (2014): Structure of the VipA/B Type VI Secretion Complex Suggests a Contraction-State-Specific Recycling Mechanism. In: Cell Reports, Vol. 8, No. 1: pp. 20-30 [PDF, 4MB]

Mirkovic-Hösle, Milijana and Förstemann, Klaus (2014): Transposon Defense by Endo-siRNAs, piRNAs and Somatic pilRNAs in Drosophila: Contributions of Loqs-PD and R2D2.
In: PLOS ONE 9(1), e84994 [PDF, 892kB]

Morozov, Yaroslav I.; Agaronyan, Karen; Cheung, Alan C. M.; Anikin, Michael; Cramer, Patrick and Temiakov, Dmitry (2014): A novel intermediate in transcription initiation by human mitochondrial RNA polymerase. In: Nucleic Acids Research, Vol. 42, No. 6: pp. 3884-3893 [PDF, 2MB]

Mühlbacher, Wolfgang; Sainsbury, Sarah; Hemann, Matthias; Hantsche, Merle; Neyer, Simon; Herzog, Franz and Cramer, Patrick (2014): Conserved architecture of the core RNA polymerase II initiation complex. In: Nature Communications, Vol. 5, 4310 [PDF, 854kB]

Pfeffer, Stefan; Dudek, Johanna; Gogala, Marko; Schorr, Stefan; Linxweiler, Johannes; Lang, Sven; Becker, Thomas; Beckmann, Roland; Zimmermann, Richard and Foerster, Friedrich (2014): Structure of the mammalian oligosaccharyl-transferase complex in the native ER protein translocon. In: Nature Communications, Vol. 5, 3072

Preis, Anne; Heuer, Andre; Barrio-Garcia, Clara; Hauser, Andreas

; Eyler, Daniel E.; Berninghausen, Otto; Green, Rachel; Becker, Thomas and Beckmann, Roland (2014): Cryoelectron Microscopic Structures of Eukaryotic Translation Termination Complexes Containing eRF1-eRF3 or eRF1-ABCE1. In: Cell Reports, Vol. 8, No. 1: pp. 59-65 [PDF, 2MB]

Runge, Simon; Sparrer, Konstantin M. J.; Lässig, Charlotte; Hembach, Katharina; Baum, Alina; Garcia-Sastre, Adolfo; Söding, Johannes; Conzelmann, Karl-Klaus and Hopfner, Karl-Peter (2014): In Vivo Ligands of MDA5 and RIG-I in Measles Virus-Infected Cells.
In: PLOS Pathogens 10(4), e1004081 [PDF, 1MB]

Schäfer, Matthias; Willrodt, Ann-Helen; Kurinna, Svitlana; Link, Andrea S.; Farwanah, Hany; Geusau, Alexandra; Gruber, Florian; Sorg, Olivier; Huebner, Aaron J.; Roop, Dennis R.; Sandhoff, Konrad; Saurat, Jean-Hilaire; Tschachler, Erwin; Schneider, Marlon R.; Langbein, Lutz; Bloch, Wilhelm; Beer, Hans-Dietmar and Werner, Sabine (2014): Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice. In: Embo Molecular Medicine, Vol. 6, No. 4: pp. 442-457 [PDF, 3MB]

Sydow, Jasmin F.; Lipsmeier, Florian; Larraillet, Vincent; Hilger, Maximiliane; Mautz, Björn; Mølhøj,, Michael; Kuentzer, Jan; Klostermann, Stefan; Schoch, Jürgen; Voelger, Hans R.; Regula, Jörg T.; Cramer, Patrick; Papadimitriou, Apollon and Kettenberger, Hubert (2014): Structure-Based Prediction of Asparagine and Aspartate Degradation Sites in Antibody Variable Regions.
In: PLOS ONE 9(6), e100736 [PDF, 1MB]

Wickles, Stephan; Singharoy, Abhishek; Andreani, Jessica; Seemayer, Stefan; Bischoff, Lukas; Berninghausen, Otto; Soeding, Johannes; Schulten, Klaus; Sluis, Eli O. van der and Beckmann, Roland (2014): A structural model of the active ribosome-bound membrane protein insertase YidC. In: eLife, Vol. 3, e03035 [PDF, 3MB]

Zacher, Benedikt; Lidschreiber, Michael; Cramer, Patrick; Gagneur, Julien and Tresch, Achim (2014): Annotation of genomics data using bidirectional hidden Markov models unveils variations in Pol II transcription cycle. In: Molecular Systems Biology, Vol. 10, No. 12, 768 [PDF, 2MB]

2013

Lammens, Alfred; Baehner, Monika; Kohnert, Ulrich; Niewoehner, Jens; Proff, Leopold von; Schraeml, Michael; Lammens, Katja and Hopfner, Karl-Peter (2013): Crystal Structure of Human TWEAK in Complex with the Fab Fragment of a Neutralizing Antibody Reveals Insights into Receptor Binding.
In: PLOS ONE 8(5), e62697 [PDF, 1MB]

Zhavoronkov, Alex and Litovchenko, Maria (November 2013): Biomedical Progress Rates as New Parameters for Models of Economic Growth in Developed Countries. In: International Journal of Environmental Research and Public Health, Vol. 10, No. 11: pp. 5936-5952 [PDF, 872kB]

2012

Helfer, Stephanie; Schott, Johanna; Stoecklin, Georg and Förstemann, Klaus (2012): AU-rich element-mediated mRNA decay can occur independently of the miRNA machinery in mouse embryonic fibroblasts and Drosophila S2-cells.
In: PLOS ONE 7(1), e28907 [PDF, 609kB]

Mohr, Hermine; Mohr, Christian A.; Schneider, Marlon R.; Scrivano, Laura; Adler, Barbara; Kraner-Scheiber, Simone; Schnieke, Angelika; Dahlhoff, Maik; Wolf, Eckhard; Koszinowski, Ulrich H. and Ruzsics, Zsolt (2012): Cytomegalovirus replicon-based regulation of gene expression in vitro and in vivo.
In: PLOS Pathogens 8(6), e1002728 [PDF, 2MB]

Niederberger, Theresa; Etzold, Stefanie; Lidschreiber, Michael; Maier, Kerstin C.; Martin, Dietmar E.; Fröhlich, Holger; Cramer, Patrick and Tresch, Achim (2012): MC EMiNEM maps the interaction landscape of the Mediator.
In: PLOS Computational Biology 8(6), e1002568 [PDF, 775kB]

2011

Linkner, Joern; Witte, Gregor; Stradal, Theresia; Curth, Ute and Faix, Jan (2011): High-resolution X-ray structure of the trimeric Scar/WAVE-complex precursor Brk1.
In: PLOS ONE 6(6), e21327 [PDF, 808kB]

Mignan, Sirine El Houry; Witte, Gregor; Naue, Natalie and Curth, Ute (2011): Characterization of the chi psi subcomplex of Pseudomonas aeruginosa DNA polymerase III. In: BMC Molecular Biology 12:43 [PDF, 2MB]

Seizl, Martin; Hartmann, Holger; Hoeg, Frederike; Kurth, Fabian; Martin, Dietmar E.; Söding, Johannes and Cramer, Patrick (September 2011): A Conserved GA Element in TATA-Less RNA Polymerase II Promoters.
In: PLOS ONE 6(11), e27595 [PDF, 988kB]

2008

Agarwal, Vatsal; Remmert, Michael; Biegert, Andreas and Soeding, Johannes (2008): PDBalert: automatic, recurrent remote homology tracking and protein structure prediction. In: BMC Structural Biology 8:51 [PDF, 463kB]

1991

Rücknagel, K. P.; Wiesner, Henning and Braunitzer, G. (1991): Carnivora. The primary Structure of the Beach Marten (Martes Foina, Mustelidae) Hemoglobin. In: Biological chemistry Hoppe-Seyler, Vol. 371: pp. 503-509 [PDF, 1MB]

1988

Rücknagel, Karl Peter; Braunitzer, Gerhard and Wiesner, Henning (1988): Hemoglobins of Reptiles. The Primary Structures og the α'- and β'-Chains of Common Iguana (Iguana iguana) Hemoglobin. In: Biological chemistry Hoppe-Seyler, Vol. 369: pp. 1143-1150 [PDF, 1MB]

1986

Hofmann, O.; Schreitmüller, T.; Braunitzer, G. and Wiesner, Henning (1986): Die Primärstruktur der Hämoglobine von Eisbär (Ursus maritimus, carnivora) und Kragenbär (Ursus tibetanus, Carnivora). In: Biological chemistry Hoppe-Seyler, Vol. 367: pp. 53-59 [PDF, 1MB]

1985

Lalthantluanga, R.; Wiesner, Henning and Braunitzer, G. (1985): Studies on Yak Hemoglobin (Bos Grunniens, Bovidae). Structural Basis for High Intrinsic Oxygen Affinity? In: Biological chemistry Hoppe-Seyler, Vol. 366: pp. 63-68 [PDF, 1MB]

Rodewald, K.; Wiesner, Henning and Braunitzer, G. (1985): Primary Structure of the Hemoglobins from the Greater Kudu Antelope Tragelaphus strepsiceros). In: Biological chemistry Hoppe-Seyler, Vol. 366: pp. 395-402 [PDF, 1MB]

1984

Braunitzer, G.; Stangl, A.; Schrank, B.; Krombach, C. and Wiesner, Henning (1984): The Primary Structur of the Haemoglobin of the African Elephant (Loxodonta africana, Proboscidae). Asparagine in Position 2 of the β-Chain. In: Hoppe-Seyler's Zeitschrift für physiologische Chemie, Vol. 365: pp. 743-749 [PDF, 3MB]

1983

Oberthür, W.; Wiesner, Henning and Braunitzer, G. (1983): Die Primärstruktur der α und β-Ketten der Hauptkomponente. In: Hoppe-Seyler's Zeitschrift für physiologische Chemie, Vol. 364: pp. 51-59 [PDF, 992kB]

1982

Oberthür, W.; Godovac-Zimmermann, J.; Braunitzer, G. and Wiesner, Henning (1982): The Amino Acid Sequence of Canada Goose and Mute Swan Hemoglobins. In: Hoppe-Seyler's Zeitschrift für physiologische Chemie, Vol. 363: pp. 777-787 [PDF, 7MB]

1980

Braunitzer, Gerdard; Schrank, Barbara; Stangl, Anton and Wiesner, Henning (1980): Respiration at High Altitudes, Phosphate-Protein-Interaction: Sequence of the Hemoglobins of the Hamster (Mesocricetus aureatus) and the Camel (Camelus ferus, Camelidae)., Höhenatmung, Phosphat-Protein-Wechselwirkung: Die Sequenz der Hämoglobine des Goldhamsters (Mesocricetus aureatus) und des zweihöckerigen Kamels (Trampeltier, Camelus ferus, Camelidae). In: Journal of the Chemical Society of Pakistan, Vol. 2, No. 1: pp. 1-7 [PDF, 775kB]

1979

Braunitzer, G.; Schrank, B.; Stangl, A. and Wiesner, Henning (1979): Höhenatmung, Phosphat-Protein Wechselwirkung. Die Sequenz der Hämoglobine des Meerschweinchens und des Dromedars. In: Hoppe-Seyler's Zeitschrift für physiologische Chemie, Vol. 360: pp. 1941-1946 [PDF, 18MB]

This list was generated on Wed Dec 6 18:39:02 2023 CET.