Number of items at this level: 614.
2024
Bérouti, Marleen; Lammens, Katja; Heiss, Matthias; Hansbauer, Larissa; Bauernfried, Stefan; Stöckl, Jan; Pinci, Francesca; Piseddu, Ignazio; Greulich, Wilhelm; Wang, Meiyue; Jung, Christophe; Fröhlich, Thomas; Carell, Thomas ORCID: https://orcid.org/0000-0001-7898-2831; Hopfner, Karl-Peter ORCID: https://orcid.org/0000-0002-4528-8357 und Hornung, Veit ORCID: https://orcid.org/0000-0002-4150-194X
(2024):
Lysosomal endonuclease RNase T2 and PLD exonucleases cooperatively generate RNA ligands for TLR7 activation.
In: Immunity, Vol. 57, No. 7: pp. 1482-1496
[PDF, 5MB]
2023
Kuhl, Niklas ORCID: https://orcid.org/0000-0003-4970-4677; Linder, Andreas ORCID: https://orcid.org/0000-0002-0623-5105; Philipp, Nora ORCID: https://orcid.org/0000-0002-3918-7795; Nixdorf, Daniel ORCID: https://orcid.org/0000-0003-1612-9952; Fischer, Hannah ORCID: https://orcid.org/0000-0003-0540-1930; Veth, Simon; Kuut, Gunnar; Xu, Teng Teng ORCID: https://orcid.org/0000-0001-9129-913X; Theurich, Sebastian ORCID: https://orcid.org/0000-0001-5706-8258; Carell, Thomas; Subklewe, Marion ORCID: https://orcid.org/0000-0001-9154-9469 und Hornung, Veit ORCID: https://orcid.org/0000-0002-4150-194X
(2023):
STING agonism turns human T cells into interferon‐producing cells but impedes their functionality.
In: EMBO reports, Vol. 24, No. 3
[PDF, 1MB]
2022
Ahn, Minkoo; Wlodarski, Tomasz; Mitropoulou, Alkistis; Chan, Sammy H. S.; Sidhu, Haneesh; Plessa, Elena; Becker, Thomas A.; Budisa, Nediljko; Waudby, Christopher A.; Beckmann, Roland; Cassaignau, Anais M. E.; Cabrita, Lisa D. und Christodoulou, John
(2022):
Modulating co-translational protein folding by rational design and ribosome engineering.
In: Nature Communications, Vol. 13, No. 1, 4243
Armbruster, Julia; Aboouf, Mostafa A.; Gassmann, Max; Egert, Angela; Schorle, Hubert; Hornung, Veit; Schmidt, Tobias; Schmid-Burgk, Jonathan L.; Kristiansen, Glen; Bicker, Anne; Hankeln, Thomas; Zhu, Hao und Gorr, Thomas A.
(2022):
Myoglobin regulates fatty acid trafficking and lipid metabolism in mammary epithelial cells.
In: PLOS One
17(10), e0275725
Bauer, Niels; Oswald, Benedikt; Eiche, Maximilian; Schiller, Lisa; Langguth, Emma; Schantz, Christian; Osterlehner, Andrea; Shen, Amy; Misaghi, Shahram; Stingele, Julian und Auslaender, Simon
(2022):
An arrayed CRISPR screen reveals Myc depletion to increase productivity of difficult-to-express complex antiboaies in CHO cells.
In: Synthetic Biology, Vol. 7, No. 1
Brehm, Julian; Wilde, Magdalena V.; Reiche, Lukas; Leitner, Lisa-Cathrin; Petran, Benedict; Meinhart, Marcel; Wieland, Simon; Ritschar, Sven; Schott, Matthias; Boos, Jan-Pascal; Frei, Sven; Kress, Holger; Senker, Juergen; Greiner, Andreas; Froehlich, Thomas und Laforsch, Christian
(2022):
In-depth characterization revealed polymer type and chemical content specific effects of microplastic on Dreissena bugensis.
In: Journal of Hazardous Materials, Vol. 437, 129351
Buckel, Wolfgang; Beatrix, Birgitta und Zelder, Oskar
(2022):
Glutamate mutase and 2-methyleneglutarate mutase.
In: Marsh, E. Neil G. (ed.) :
Coenzyme B12 Enzymes. Part A. Methods in enzymology, Vol. 668. Cambridge, MA ; San Diego, CA ; Oxford ; London: Academic Press, an imprint of Elsevier. pp. 285-307
Czech, Laura; Mais, Christopher-Nils; Kratzat, Hanna; Sarmah, Pinku; Giammarinaro, Pietro; Freibert, Sven-Andreas; Esser, Hanna Folke; Musial, Joanna; Berninghausen, Otto; Steinchen, Wieland; Beckmann, Roland; Koch, Hans-Georg und Bange, Gert
(2022):
Inhibition of SRP-dependent protein secretion by the bacterial alarmone (p)ppGpp.
In: Nature Communications, Vol. 13, No. 1, 1069
Fahrmann, Johannes F.; Saini, Neeraj Y.; Chia-Chi, Chang; Irajizad, Ehsan; Strati, Paolo; Nair, Ranjit; Fayad, Luis E.; Ahmed, Sairah; Lee, Hun Ju; Iyer, Swaminathan; Steiner, Raphael; Vykoukal, Jody; Wu, Ranran; Dennison, Jennifer B.; Nastoupil, Loretta; Jain, Preetesh; Wang, Michael; Green, Michael; Westin, Jason; Blumenberg, Viktoria; Davila, Marco; Champlin, Richard; Shpall, Elizabeth J.; Kebriaei, Partow; Flowers, Christopher R.; Jain, Michael; Jenq, Robert; Stein-Thoeringer, Christoph K.; Subklewe, Marion; Neelapu, Sattva S. und Hanash, Sam
(2022):
A polyamine-centric, blood-based metabolite panel predictive of poor response to CAR-T cell therapy in B cell lymphoma.
In: Cell Reports Medicine, Vol. 3, No. 11, 100720
Gut, Fabian; Kaeshammer, Lisa; Lammens, Katja; Bartho, Joseph D.; Boggusch, Anna-Maria; Logt, Erik van de; Kessler, Brigitte und Hopfner, Karl-Peter
(2022):
Structural mechanism of endonucleolytic processing of blocked DNA ends and hairpins by Mre11-Rad50.
In: Molecular Cell, Vol. 82, No. 18: pp. 3513-3522
Hohle, Markus Matthias; Lammens, Katja; Gut, Fabian; Wang, Bingzhi; Kahler, Sophia; Kugler, Kathrin; Till, Michael; Beckmann, Roland; Hopfner, Karl-Peter und Jung, Christophe
(12. September 2022):
Ice thickness monitoring for cryo-EM grids by interferometry imaging.
In: Scientific Reports, Vol. 12
[PDF, 2MB]
Ismail, Sherif; Flemming, Dirk; Thoms, Matthias; Gomes-Filho, Jose Vicente; Randau, Lennart; Beckmann, Roland und Hurt, Ed
(2022):
Emergence of the primordial pre-60S from the 90S pre-ribosome.
In: Cell Reports, Vol. 39, No. 1, 110640
Kessler, Nina; Viehmann, Susanne F.; Krollmann, Calvin; Mai, Karola; Kirschner, Katharina M.; Luksch, Hella; Kotagiri, Prasanti; Böhner, Alexander M. C.; Huugen, Dennis; Mann, Carina C. de Oliveira; Otten, Simon; Weiss, Stefanie A. I.; Zillinger, Thomas; Dobrikova, Kristiyana; Jenne, Dieter E.; Behrendt, Rayk; Ablasser, Andrea; Bartok, Eva; Hartmann, Gunther; Hopfner, Karl-Peter; Lyons, Paul A.; Boor, Peter; Rösen-Wolff, Angela; Teichmann, Lino L.; Heeringa, Peter; Kurts, Christian und Garbi, Natalio
(2022):
Monocyte-derived macrophages aggravate pulmonary vasculitis via cGAS/STING/IFN-mediated nucleic acid sensing.
In: Journal of Experimental Medicine, Vol. 219, No. 10, e20220759
Kim, Nam-Shik; Ringeling, Francisca Rojas; Zhou, Ying; Nguyen, Ha Nam; Temme, Stephanie J.; Lin, Yu-Ting; Eacker, Stephen; Dawson, Valina L.; Dawson, Ted M.; Xiao, Bo; Hsu, Kuei-sen; Canzar, Stefan; Li, Weidong; Worley, Paul; Christian, Kimberly M.; Yoon, Ki-Jun; Song, Hongjun und Ming, Guo-li
(2022):
CYFIP1 Dosages Exhibit Divergent Behavioral Impact via Diametric Regulation of NMDA Receptor Complex Translation in Mouse Models of Psychiatric Disorders.
In: Biological Psychiatry, Vol. 92, No. 10: pp. 815-826
Kugler, Michael; Hadzima, Martin; Dzijak, Rastislav; Rampmaier, Robert; Srb, Pavel; Vrzal, Lukas; Voburka, Zdenek; Majer, Pavel; Rezacova, Pavlina und Vrabel, Milan
(2022):
Identification of specific carbonic anhydrase inhibitors via in situ click chemistry, phage-display and synthetic peptide libraries: comparison of the methods and structural study.
In: Rsc Medicinal Chemistry, Vol. 14, No. 1: pp. 144-153
Kuhn, Laura B.; Valentin, Stefanie; Stojanovic, Kristina; Strobl, Daniel C.; Babushku, Tea; Wang, Yan; Rambold, Ursula; Scheffler, Laura; Grath, Sonja; John-Robbert, Dorothy; Blum, Helmut; Feuchtinger, Annette; Blutke, Andreas; Weih, Falk; Kitamura, Daisuke; Rad, Roland; Strobl, Lothar J. und Zimber-Strobl, Ursula
(2022):
RelB contributes to the survival, migration and lymphomagenesis of B cells with constitutively active CD40 signaling.
In: Frontiers in Immunology, Vol. 13, 913275
Kunert, Franziska; Metzner, Felix J.; Jung, James; Höpfler, Markus; Woike, Stephan; Schall, Kevin; Kostrewa, Dirk; Moldt, Manuela; Chen, Jia-Xuan; Bantele, Susanne; Pfander, Boris; Eustermann, Sebastian und Hopfner, Karl-Peter
(2022):
Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
In: Science Advances, Vol. 8, No. 49
[PDF, 3MB]
Lau, Benjamin; Beine-Golovchuk, Olga; Kornprobst, Markus; Cheng, Jingdong; Kressler, Dieter; Jady, Beata; Kiss, Tamas; Beckmann, Roland und Hurt, Ed
(2022):
Cms1 coordinates stepwise local 90S pre-ribosome assembly with timely snR83 release.
In: Cell Reports, Vol. 41, No. 8, 111684
Li, Sihan; Ikeuchi, Ken; Kato, Misaki; Buschauer, Robert; Sugiyama, Takato; Adachi, Shungo; Kusano, Hideo; Natsume, Tohru; Berninghausen, Otto; Matsuo, Yoshitaka; Becker, Thomas; Beckmann, Roland und Inada, Toshifumi
(2022):
Sensing of individual stalled 80S ribosomes by Fap1 for nonfunctional rRNA turnover.
In: Molecular Cell, Vol. 82, No. 18, E8: pp. 3424-3437
Linder, Andreas und Hornung, Veit
(2022):
Inflammasomes in T cells.
In: Journal of Molecular Biology, Vol. 434, No. 4, 167275
Mangan, Matthew S. J.; Gorki, Friederike; Krause, Karoline; Heinz, Alexander; Pankow, Anne; Ebert, Thomas; Jahn, Dieter; Hiller, Karsten; Hornung, Veit; Maurer, Marcus; Schmidt, Florian I.; Gerhard, Ralf und Latz, Eicke
(2022):
Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever.
In: PLOS Biology
20(11), e3001351
Menegatti, Jennifer; Nakel, Jacqueline; Stepanov, Youli K.; Caban, Karolina M.; Ludwig, Nicole; Nord, Ruth; Pfitzner, Thomas; Yazdani, Maryam; Vilimova, Monika; Kehl, Tim; Lenhof, Hans-Peter; Philipp, Stephan E.; Meese, Eckart; Froehlich, Thomas; Graesser, Friedrich A. und Hart, Martin
(2022):
Changes of Protein Expression after CRISPR/Cas9 Knockout of miRNA-142 in Cell Lines Derived from Diffuse Large B-Cell Lymphoma.
In: Cancers, Vol. 14, No. 20, 5031
Narita, Momoko; Denk, Timo; Matsuo, Yoshitaka; Sugiyama, Takato; Kikuguchi, Chisato; Ito, Sota; Sato, Nichika; Suzuki, Toru; Hashimoto, Satoshi; Machova, Iva; Tesina, Petr; Beckmann, Roland und Inada, Toshifumi
(2022):
A distinct mammalian disome collision interface harbors K63-linked polyubiquitination of uS10 to trigger hRQT-mediated subunit dissociation.
In: Nature Communications, Vol. 13, No. 1, 6411
Nchioua, Rayhane; Schundner, Annika; Kmiec, Dorota; Bozzo, Prelli Caterina; Zech, Fabian; Koepke, Lennart; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Frick, Manfred; Sparrer, Konstantin M. J. und Kirchhoff, Frank
(2022):
SARS-CoV-2 Variants of Concern Hijack IFITM2 for Efficient Replication in Human Lung Cells.
In: Journal of Virology, Vol. 96, No. 11
Nishiumi, Haruka; Deiringer, Natalie; Krause, Nils; Yoneda, Saki; Torisu, Tetsuo; Menzen, Tim; Friess, Wolfgang und Uchiyama, Susumu
(2022):
Utility of Three Flow Imaging Microscopy Instruments for Image Analysis in Evaluating four Types of Subvisible Particle in Biopharmaceuticals.
In: Journal of Pharmaceutical Sciences, Vol. 111, No. 11: pp. 3017-3028
Qi, Zhan; Jung, Christophe; Bandilla, Peter; Ludwig, Claudia; Heron, Mark; Sophie Kiesel, Anja; Museridze, Mariam; Philippou‐Massier, Julia; Nikolov, Miroslav; Renna Max Schnepf, Alessio; Unnerstall, Ulrich; Ceolin, Stefano; Mühlig, Bettina; Gompel, Nicolas; Soeding, Johannes und Gaul, Ulrike
(14. February 2022):
Large‐scale analysis of Drosophila core promoter function using synthetic promoters.
In: Molecular Systems Biology, Vol. 18, No. 2
[PDF, 3MB]
Robinson, Kim S.; Toh, Gee Ann; Rozario, Pritisha; Chua, Rae; Bauernfried, Stefan; Sun, Zijin; Firdaus, Muhammad Jasrie; Bayat, Shima; Nadkarni, Rhea; Poh, Zhi Sheng; Tham, Khek Chian; Harapas, Cassandra R.; Lim, Chrissie K.; Chu, Werncui; Tay, Celest W. S.; Tan, Kiat Yi; Zhao, Tianyun; Bonnard, Carine; Sobota, Radoslaw; Connolly, John E.; Common, John; Masters, Seth L.; Chen, Kaiwen W.; Ho, Lena; Wu, Bin; Hornung, Veit und Zhong, Franklin L.
(2022):
ZAK alpha-driven ribotoxic stress response activates the human NLRP1 inflammasome.
In: Science, Vol. 377, No. 6603: pp. 328-334
Saito, Kazuki; Kratzat, Hanna; Campbell, Annabelle; Buschauer, Robert; Burroughs, A. Maxwell; Berninghausen, Otto; Aravind, L.; Green, Rachel; Beckmann, Roland und Buskirk, Allen R.
(2022):
Ribosome collisions induce mRNA cleavage and ribosome rescue in bacteria.
In: Nature, Vol. 603, No. 7901: pp. 503-508
Schubert, Nadja; Schumann, Tina; Daum, Elena; Flade, Karolin; Ge, Yan; Hagedorn, Lara; Edelmann, Winfried; Mueller, Luise; Schmitz, Marc; Kuut, Gunnar; Hornung, Veit; Behrendt, Rayk und Roers, Axel
(2022):
Genome Replication Is Associated With Release of Immunogenic DNA Waste.
In: Frontiers in Immunology, Vol. 13, 880413
Shammas, Mario K.; Huang, Xiaoping; Wu, Beverly P.; Fessler, Evelyn; Song, Insung Y.; Randolph, Nicholas P.; Li, Yan; Bleck, Christopher K. E.; Springer, Danielle A.; Fratter, Carl; Barbosa, Ines A.; Powers, Andrew F.; Quiros, Pedro M.; Lopez-Otin, Carlos; Jae, Lucas T.; Poulton, Joanna und Narendra, Derek P.
(2022):
OMA1 mediates local and global stress responses against protein misfolding in CHCHD10 mitochondrial.
In: Journal of Clinical Investigation, Vol. 132, No. 14, e157504
Spielmann, Nadine; Schenkl, Christina; Komlodi, Timea; da Silva-Buttkus, Patricia; Heyne, Estelle; Rohde, Jana; Amarie, Oana V.; Rathkolb, Birgit; Gnaiger, Erich; Doenst, Torsten; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin und Szibor, Marten
(2022):
Knockout of the Complex III subunit Uqcrh causes bioenergetic impairment and cardiac contractile dysfunction.
In: Mammalian Genome, Vol. 34, No. 2: pp. 229-243
Stafford, Che A.; Gassauer, Alicia-Marie; Oliveira Mann, Carina C. de; Tanzer, Maria C. ORCID: https://orcid.org/0000-0002-4657-9869; Fessler, Evelyn; Wefers, Benedikt ORCID: https://orcid.org/0000-0002-2492-9389; Nagl, Dennis; Kuut, Gunnar; Sulek, Karolina; Vasilopoulou, Catherine; Schwojer, Sophia J. ORCID: https://orcid.org/0000-0002-1747-4144; Wiest, Andreas ORCID: https://orcid.org/0000-0003-2525-6304; Pfautsch, Marie K.; Wurst, Wolfgang ORCID: https://orcid.org/0000-0003-4422-7410; Yabal, Monica ORCID: https://orcid.org/0000-0003-3495-7671; Fröhlich, Thomas ORCID: https://orcid.org/0000-0002-4709-3211; Mann, Matthias ORCID: https://orcid.org/0000-0003-1292-4799; Gisch, Nicolas ORCID: https://orcid.org/0000-0003-3260-5269; Jae, Lucas T. ORCID: https://orcid.org/0000-0002-3531-1760 und Hornung, Veit ORCID: https://orcid.org/0000-0002-4150-194X
(2022):
Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation.
In: Nature, Vol. 609: pp. 590-596
[PDF, 10MB]
Stepanov, Youli Konstantinovitch; Speidel, Jan Dominik; Herrmann, Carola; Schmid, Nina; Behr, Rüdiger; Koehn, Frank-Michael; Stoeckl, Jan Bernd; Pickl, Ulrich; Trottmann, Matthias; Froehlich, Thomas; Mayerhofer, Artur und Welter, Harald
(2022):
Profound Effects of Dexamethasone on the Immunological State, Synthesis and Secretion Capacity of Human Testicular Peritubular Cells.
In: Cells, Vol. 11, No. 19, 3164
Stirm, Michael; Fonteyne, Lina Marie; Shashikadze, Bachuki; Stoeckl, Jan B.; Kurome, Mayuko; Kessler, Barbara; Zakhartchenko, Valeri; Kemter, Elisabeth; Blum, Helmut; Arnold, Georg J.; Matiasek, Kaspar; Wanke, Ruediger; Wurst, Wolfgang; Nagashima, Hiroshi; Knieling, Ferdinand; Walter, Maggie C.; Kupatt, Christian; Froehlich, Thomas; Klymiuk, Nikolai; Blutke, Andreas und Wolf, Eckhard
(2022):
Pig models for Duchenne muscular dystrophy-from disease mechanisms to validation of new diagnostic and therapeutic concepts.
In: Neuromuscular Disorders, Vol. 32, No. 7: pp. 543-556
Synakewicz, Marie; Eapen, Rohan S.; Perez-Riba, Albert; Rowling, Pamela J. E.; Bauer, Daniela; Weissl, Andreas; Fischer, Gerhard; Hyvonen, Marko; Rief, Matthias; Itzhaki, Laura S. und Stigler, Johannes
(2022):
Unraveling the Mechanics of a Repeat-Protein Nanospring: From Folding of Individual Repeats to Fluctuations of the Superhelix.
In: ACS Nano, Vol. 16, No. 3: pp. 3895-3905
Tomomatsu, Shota; Watanabe, Atsuya; Tesina, Petr; Hashimoto, Satoshi; Ikeuchi, Ken; Li, Sihan; Matsuo, Yoshitaka; Beckmann, Roland und Inada, Toshifumi
(2022):
Two modes of Cue2-mediated mRNA cleavage with distinct substrate recognition initiate no-go decay.
In: Nucleic Acids Research, Vol. 51, No. 1: pp. 253-270
Ugolini, Ilaria; Bilokapic, Silvija; Ferrolino, Mylene; Teague, Josiah; Yan, Yinxia; Zhou, Xuelin; Deshmukh, Ashish; White, Michael; Kriwacki, Richard W. und Halic, Mario
(2022):
Chromatin localization of nucleophosmin organizes ribosome biogenesis.
In: Molecular Cell, Vol. 82, No. 23: pp. 4443-4457
Vegas, Alba Rudolf; Hamdi, Meriem; Podico, Giorgia; Bollwein, Heinrich; Froehlich, Thomas; Canisso, Igor F.; Bauersachs, Stefan und Alminana, Carmen
(2022):
Uterine extracellular vesicles as multi-signal messengers during maternal recognition of pregnancy in the mare.
In: Scientific Reports, Vol. 12, No. 1, 15616
Vieira, Vinicius A.; Adland, Emily; Grayson, Nicholas E.; Csala, Anna; Richards, Fa'eeda; Dacon, Cherrelle; Athavale, Rohin; Tsai, Ming-Han; D'Souza, Reena; Muenchhoff, Maximilian; Bonsall, David; Jooste, Pieter und Goulder, Philip J. R.
(2022):
Two Distinct Mechanisms Leading to Loss of Virological Control in the Rare Group of Antiretroviral Therapy-Naive, Transiently Aviremic Children Living with HIV.
In: Journal of Virology, Vol. 96, No. 2, e01535-21
Wratil, Paul R.; Stern, Marcel; Priller, Alina; Willmann, Annika; Almanzar, Giovanni; Vogel, Emanuel; Feuerherd, Martin; Cheng, Cho-Chin; Yazici, Sarah; Christa, Catharina; Jeske, Samuel; Lupoli, Gaia; Vogt, Tim; Albanese, Manuel; Mejias-Perez, Ernesto; Bauernfried, Stefan; Graf, Natalia; Mijocevic, Hrvoje; Vu, Martin; Tinnefeld, Kathrin; Wettengel, Jochen; Hoffmann, Dieter; Muenchhoff, Maximilian; Daechert, Christopher; Mairhofer, Helga; Krebs, Stefan; Fingerle, Volker; Graf, Alexander; Steininger, Philipp; Blum, Helmut; Hornung, Veit; Liebl, Bernhard; Ueberla, Klaus; Prelog, Martina; Knolle, Percy; Keppler, Oliver T. und Protzer, Ulrike
(2022):
Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern.
In: Nature Medicine, Vol. 28, No. 3: pp. 496-503
2021
Alminana, Carmen; Rudolf Vegas, Alba; Tekin, Muhittin; Hassan, Mubbashar; Uzbekov, Rustem; Frohlich, Thomas; Bollwein, Heinrich und Bauersachs, Stefan
(2021):
Isolation and Characterization of Equine Uterine Extracellular Vesicles: A Comparative Methodological Study.
In: International Journal of Molecular Sciences, Vol. 22, No. 2, 979
Altstetter, Sebastian Maximilian; Quitt, Oliver; Pinci, Francesca; Hornung, Veit; Lucko, Aaron Michael; Wisskirchen, Karin; Jung, Stephanie und Protzer, Ulrike
(2021):
Hepatitis-D Virus Infection Is Not Impaired by Innate Immunity but Increases Cytotoxic T-Cell Activity.
In: Cells, Vol. 10, No. 11, 3253
Brandt, Margot; Kim-Hellmuth, Sarah; Ziosi, Marcello; Gokden, Alper; Wolman, Aaron; Lam, Nora; Recinos, Yocelyn; Daniloski, Zharko; Morris, John A.; Hornung, Veit; Schumacher, Johannes und Lappalainen, Tuuli
(2021):
An autoimmune disease risk variant: A trans master regulatory effect mediated by IRF1 under immune stimulation?
In: PLOS Genetics
17(7), e1009684
Caballero, Ignacio; Ringot-Destrez, Belinda; Si-Tahar, Mustapha; Barbry, Pascal; Guillon, Antoine; Lantier, Isabelle; Berri, Mustapha; Chevaleyre, Claire; Fleurot, Isabelle; Barc, Celine; Ramphal, Reuben; Pons, Nicolas; Paquet, Agnes; Lebrigand, Kevin; Baron, Carole; Baehr, Andrea; Klymiuk, Nikolai; Leonard, Renaud und Robbe-Masselot, Catherine
(2021):
Evidence of early increased sialylation of airway mucins and defective mucociliary clearance in CFTR-deficient piglets.
In: Journal of Cystic Fibrosis, Vol. 20, No. 1: pp. 173-182
Ghosh, Suvoshree; Kraus, Katrin; Biswas, Arijit; Mueller, Jens; Forin, Francesco; Singer, Heike; Höning, Klara; Hornung, Veit; Watzka, Matthias; Oldenburg, Johannes und Czogalla-Nitsche, Katrin J.
(2021):
GGCX variants leading to biallelic deficiency to gamma-carboxylate GRP cause skin laxity in VKCFD1 patients.
In: Human Mutation, Vol. 43, No. 1: pp. 42-55
Ghosh, Suvoshree; Kraus, Katrin; Biswas, Arijit; Müller, Jens; Buhl, Anna-Lena; Forin, Francesco; Singer, Heike; Höning, Klara; Hornung, Veit; Watzka, Matthias; Czogalla-Nitsche, Katrin J. und Oldenburg, Johannes
(2021):
GGCX mutations show different responses to vitamin K thereby determining the severity of the hemorrhagic phenotype in VKCFD1 patients.
In: Journal of Thrombosis and Haemostasis, Vol. 19, No. 6: pp. 1412-1424
Hnizda, Ales; Tesina, Petr; Nguyen, Thanh-Binh; Kukacka, Zdenek; Kater, Lukas; Chaplin, Amanda; Beckmann, Roland; Ascher, David B.; Novak, Petr und Blundell, Tom L.
(2021):
SAP domain forms a flexible part of DNA aperture in Ku70/80.
In: Febs Journal, Vol. 288, No. 14: pp. 4382-4393
Huang, Bin; Guo, Qiang; Niedermeier, Marie L.; Cheng, Jingdong; Engler, Tatjana; Maurer, Melanie; Pautsch, Alexander; Baumeister, Wolfgang; Stengel, Florian; Kochanek, Stefan und Fernandez-Busnadiego, Ruben
(2021):
Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex.
In: Structure, Vol. 29, No. 8: pp. 804-809
Kirstein, Nina; Buschle, Alexander; Wu, Xia; Krebs, Stefan; Blum, Helmut; Kremmer, Elisabeth; Vorberg, Ina M.; Hammerschmidt, Wolfgang; Lacroix, Laurent; Hyrien, Olivier; Audit, Benjamin und Schepers, Aloys
(2021):
Human ORC/MCM density is low in active genes and correlates with replication time but does not delimit initiation zones.
In: eLife, Vol. 10, e62161
[PDF, 1MB]
Kratzat, Hanna; Mackens‐Kiani, Timur; Ameismeier, Michael; Potocnjak, Mia; Cheng, Jingdong; Dacheux, Estelle; Namane, Abdelkader; Berninghausen, Otto; Herzog, Franz ORCID: https://orcid.org/0000-0001-8270-1449; Fromont‐Racine, Micheline; Becker, Thomas und Beckmann, Roland
(2021):
A structural inventory of native ribosomal ABCE1‐43S pre‐initiation complexes.
In: EMBO, Vol. 40, No. 1
[PDF, 12MB]
Lenz, Jonathan ORCID: https://orcid.org/0000-0003-2172-035X; Liefke, Robert ORCID: https://orcid.org/0000-0002-8549-637X; Funk, Julianne ORCID: https://orcid.org/0000-0002-1848-7975; Shoup, Samuel ORCID: https://orcid.org/0000-0001-8119-3534; Nist, Andrea ORCID: https://orcid.org/0000-0002-7524-6801; Stiewe, Thorsten ORCID: https://orcid.org/0000-0003-0134-7826; Schulz, Robert; Tokusumi, Yumiko; Albert, Lea ORCID: https://orcid.org/0000-0003-4241-4538; Raifer, Hartmann; Förstemann, Klaus ORCID: https://orcid.org/0000-0003-3641-6342; Vazquez, Olalla; Tokusumi, Tsuyoshi; Fossett, Nancy und Brehm, Alexander ORCID: https://orcid.org/0000-0002-6237-4898
(2021):
Ush regulates hemocyte-specific gene expression, fatty acid metabolism and cell cycle progression and cooperates with dNuRD to orchestrate hematopoiesis.
In: PLOS Genetics
17(2), e1009318
[PDF, 3MB]
Li, Xiaoling; Fetter, Richard; Schwabe, Tina; Jung, Christophe; Liu, Liren; Steller, Hermann und Gaul, Ulrike
(2021):
The cAMP effector PKA mediates Moody GPCR signaling in Drosophila blood-brain barrier formation and maturation.
In: eLife, Vol. 10, e68275
[PDF, 13MB]
Linnekamp, Janneke F.; Kandimalla, Raju; Fessler, Evelyn; Jong, Joan H. de; Rodermond, Hans M.; Bochove, Gregor G. W. van; The, Frans O.; Punt, Cornelis J. A.; Bemelman, Willem A.; Ven, Anthony W. H. van de; Tanis, Pieter J.; Kemper, Elles M.; Koens, Lianne; Dekker, Evelien; Vermeulen, Louis; Laarhoven, Hanneke W. M. van und Medema, Jan Paul
(2021):
Pre-Operative Decitabine in Colon Cancer Patients: Analyses on WNT Target Methylation and Expression.
In: Cancers, Vol. 13, No. 10, 2357
Liu, Zikou; Dagley, Laura F.; Shield-Artin, Kristy; Young, Samuel N.; Bankovacki, Aleksandra; Wang, Xiangyi; Tang, Michelle; Howitt, Jason; Stafford, Che A.; Nachbur, Ueli; Fitzgibbon, Cheree; Garnish, Sarah E.; Webb, Andrew I.; Komander, David; Murphy, James M.; Hildebrand, Joanne M. und Silke, John
(2021):
Oligomerization-driven MLKL ubiquitylation antagonizes necroptosis.
In: EMBO Journal, Vol. 40, No. 23, e103718
Mertes, Christian; Scheller, Ines F.; Yepez, Vicente A.; Celik, Muhammed H.; Liang, Yingjiqiong; Kremer, Laura S.; Gusic, Mirjana; Prokisch, Holger und Gagneur, Julien
(2021):
Detection of aberrant splicing events in RNA-seq data using FRASER.
In: Nature Communications, Vol. 12, No. 1, 529
Oberbeckmann, Elisa; Niebauer, Vanessa; Watanabe, Shinya; Farnung, Lucas; Moldt, Manuela; Schmid, Andrea; Cramer, Patrick; Peterson, Craig L.; Eustermann, Sebastian; Hopfner, Karl-Peter und Korber, Philipp
(2021):
Ruler elements in chromatin remodelers set nucleosome array spacing and phasing.
In: Nature Communications, Vol. 12, No. 1, 3232
Pochopien, Agnieszka A.; Beckert, Bertrand; Kasvandik, Sergo; Berninghausen, Otto; Beckmann, Roland; Tenson, Tanel und Wilson, Daniel N.
(2021):
Structure of Gcn1 bound to stalled and colliding 80S ribosomes.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, No. 14, e2022756118
Rabanal-Ruiz, Yoana; Byron, Adam; Wirth, Alexander; Madsen, Ralitsa; Sedlackova, Lucia; Hewitt, Graeme; Nelson, Glyn; Stingele, Julian; Wills, Jimi C.; Zhang, Tong; Zeug, Andre; Faessler, Reinhard; Vanhaesebroeck, Bart; Maddocks, Oliver D. K.; Ponimaskin, Evgeni; Carroll, Bernadette und Korolchuk, Viktor
(2021):
mTORC1 activity is supported by spatial association with focal adhesions.
In: Journal of Cell Biology, Vol. 220, No. 5, e202004010
Shashikadze, Bachuki; Flenkenthaler, Florian; Stöckl, Jan B.; Valla, Libera; Renner, Simone; Kemter, Elisabeth; Wolf, Eckhard und Fröhlich, Thomas
(2021):
Developmental Effects of (Pre-)Gestational Diabetes on Offspring: Systematic Screening Using Omics Approaches.
In: Genes, Vol. 12, No. 12, 1991
Shen, Lunda; Su, Zhaoming; Yang, Kailu; Wu, Cheng; Becker, Thomas; Bell-Pedersen, Deborah; Zhang, Junjie und Sachs, Matthew S.
(2021):
Structure of the translating Neurospora ribosome arrested by cycloheximide.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, No. 48, e2111862118
Stakyte, K.; Rotheneder, M.; Lammens, K.; Bartho, J. D.; Grädler, U.; Fuchß, T.; Pehl, U.; Alt, A.; Logt, E. van de und Hopfner, K. P.
(2021):
Molecular basis of human ATM kinase inhibition.
In: Nature Structural & Molecular Biology, Vol. 28, No. 10: 789-
Tahk, Siret; Vick, Binje; Hiller, Björn; Schmitt, Saskia; Marcinek, Anetta; Perini, Enrico D.; Leutbecher, Alexandra; Augsberger, Christian; Reischer, Anna; Tast, Benjamin; Humpe, Andreas; Jeremias, Irmela; Subklewe, Marion; Fenn, Nadja C. und Hopfner, Karl-Peter
(2021):
SIRP alpha-alpha CD123 fusion antibodies targeting CD123 in conjunction with CD47 blockade enhance the clearance of AML-initiating cells.
In: Journal of Hematology & Oncology, Vol. 14, No. 1, 155
Tahk, Siret; Vick, Binje; Hiller, Björn; Schmitt, Saskia; Marcinek, Anetta; Perini, Enrico D.; Leutbecher, Alexandra; Augsberger, Christian; Reischer, Anna; Tast, Benjamin; Humpe, Andreas; Jeremias, Irmela; Subklewe, Marion; Fenn, Nadja C. und Hopfner, Karl-Peter ORCID: https://orcid.org/0000-0002-4528-8357
(2021):
SIRPα-αCD123 fusion antibodies targeting CD123 in conjunction with CD47 blockade enhance the clearance of AML-initiating cells.
In: Journal of hematology & oncology, Vol. 14, 155
[PDF, 3MB]
Trotter, Benjamin; Wilde, Magdalena; Brehm, Julian; Dafni, Evdokia; Aliu, Arlinda; Arnold, Georg J.; Fröhlich, Thomas und Laforsch, Christian
(2021):
Long-term exposure of Daphnia magna to polystyrene microplastic (PS-MP) leads to alterations of the proteome, morphology and life-history.
In: Science of the Total Environment, Vol. 795, 148822
Wratil, Paul R.; Schmacke, Niklas A.; Karakoc, Burak; Dulovic, Alex; Junker, Daniel; Becker, Matthias; Rothbauer, Ulrich; Osterman, Andreas; Spaeth, Patricia M.; Ruhle, Adrian; Gapp, Madeleine; Schneider, Stephanie; Muenchhoff, Maximilian; Hellmuth, Johannes C.; Scherer, Clemens; Mayerle, Julia; Reincke, Martin; Behr, Jürgen; Kaab, Stefan; Zwissler, Bernhard; Bergwelt-Baildon, Michael von; Eberle, Josef; Kaderali, Lars; Schneiderhan-Marra, Nicole; Hornung, Veit und Keppler, Oliver T.
(2021):
Evidence for increased SARS-CoV-2 susceptibility and COVID-19 severity related to pre-existing immunity to seasonal coronaviruses.
In: Cell Reports, Vol. 37, No. 13, 110169
Yepez, Vicente A.; Mertes, Christian; Mueller, Michaela F.; Klaproth-Andrade, Daniela; Wachutka, Leonhard; Fresard, Laure; Gusic, Mirjana; Scheller, Ines F.; Goldberg, Patricia F.; Prokisch, Holger und Gagneur, Julien
(2021):
Detection of aberrant gene expression events in RNA sequencing data.
In: Nature Protocols, Vol. 16, No. 2
Zhao, Shubo; Kieser, Anja; Li, Hao-Yi; Reinking, Hannah K.; Weickert, Pedro; Euteneuer, Simon; Yaneva, Denitsa; Acampora, Aleida C.; Goetz, Maximilian J.; Feederle, Regina und Stingele, Julian
(2021):
A ubiquitin switch controls autocatalytic inactivation of the DNA-protein crosslink repair protease SPRTN.
In: Nucleic Acids Research, Vol. 49, No. 2
2020
Basu, Aakash; Bobrovnikov, Dmitriy G.; Qureshi, Zan; Kayikcioglu, Tunc; Ngo, Thuy T. M.; Ranjan, Anand; Eustermann, Sebastian; Cieza, Basilio; Morgan, Michael T.; Hejna, Miroslav; Rube, H. Tomas; Hopfner, Karl-Peter; Wolberger, Cynthia; Song, Jun S. und Ha, Taekjip
(2020):
Measuring DNA mechanics on the genome scale.
In: Nature, Vol. 589, No. 7842: pp. 462-467
Blagotinsek, Vitan; Schwan, Meike; Steinchen, Wieland; Mrusek, Devid; Hook, John C.; Rossmann, Florian; Freibert, Sven A.; Kratzat, Hanna; Murat, Guillaume; Kressler, Dieter; Beckmann, Roland; Beeby, Morgan; Thormann, Kai M. und Bange, Gert
(2020):
An ATP-dependent partner switch links flagellar C-ring assembly with gene expression.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 34: pp. 20826-20835
Brea, Deborah; Soler, Laura; Fleurot, Isabelle; Melo, Sandrine; Chevaleyre, Claire; Berri, Mustapha; Labas, Valerie; Teixeira-Gomes, Ana-Paula; Pujo, Julien; Cenac, Nicolas; Baehr, Andrea; Klymiuk, Nikolai; Guillon, Antoine; Si-Tahar, Mustapha und Caballero, Ignacio
(2020):
Intrinsic alterations in peripheral neutrophils from cystic fibrosis newborn piglets.
In: Journal of Cystic Fibrosis, Vol. 19, No. 5: pp. 830-836
Buschauer, Robert; Matsuo, Yoshitaka; Sugiyama, Takato; Chen, Ying-Hsin; Alhusaini, Najwa; Sweet, Thomas; Ikeuchi, Ken; Cheng, Jingdong; Matsuki, Yasuko; Nobuta, Risa; Gilmozzi, Andrea; Berninghausen, Otto; Tesina, Petr; Becker, Thomas; Coller, Jeff; Inada, Toshifumi und Beckmann, Roland
(2020):
The Ccr4-Not complex monitors the translating ribosome for codon optimality.
In: Science, Vol. 368, No. 6488, eaay6912
Ceolin, Stefano; Hanf, Monika; Bozek, Marta; Storti, Andrea Ennio; Gompel, Nicolas; Unnerstall, Ulrich; Jung, Christophe und Gaul, Ulrike
(2020):
A sensitive mNeonGreen reporter system to measure transcriptional dynamics in Drosophila development.
In: Communications Biology, Vol. 3, No. 1, 663
Cunha Bustamante-Filho, Ivan; Renato Menegassi, Silvio; Ribas Pereira, Gabriel; Dias Salton, Gabrielle; Mosena Munari, Fernanda; Roberto Schneider, Marlon; Costa Mattos, Rodrigo; Otavio Jardim Barcellos, Julio; Pereira Laurino, Jomar; Obino Cirne-Lima, Elizabeth und Ines Mascarenhas Jobim, Maria
(2020):
Bovine seminal plasma osteopontin: Structural modelling, recombinant expression and its relationship with semen quality.
In: Andrologia, Vol. 53, No. 1, e13905
Fessler, Evelyn; Eckl, Eva-Maria; Schmitt, Sabine; Mancilla, Igor Alves; Meyer-Bender, Matthias F.; Hanf, Monika; Philippou-Massier, Julia; Krebs, Stefan; Zischka, Hans und Jae, Lucas T.
(2020):
A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol.
In: Nature, Vol. 579, No. 7799: pp. 433-437
Gegenfurtner, Katrin; Fröhlich, Thomas; Flenkenthaler, Florian; Koesters, Miwako; Fritz, Sebastien; Desnoes, Olivier; Le Bourhis, Daniel; Salvetti, Pascal; Sandra, Olivier; Charpigny, Gilles; Mermillod, Pascal; Lonergan, Patrick; Wolf, Eckhard und Arnold, Georg J.
(2020):
Genetic merit for fertility alters the bovine uterine luminal fluid proteome.
In: Biology of Reproduction, Vol. 102, No. 3: pp. 730-739
Ghodgaonkar-Steger, Medini; Potocnjak, Mia; Zimniak, Tomasz; Fischböck-Halwachs, Josef; Solis-Mezarino, Victor; Singh, Sylvia; Speljko, Tea; Hagemann, Götz; Drexler, David Jan; Witte, Gregor und Herzog, Franz ORCID: https://orcid.org/0000-0001-8270-1449
(2020):
C-Terminal Motifs of the MTW1 Complex Cooperatively Stabilize Outer Kinetochore Assembly in Budding Yeast.
In: Cell reports, Vol. 32, No. 13, 108190
[PDF, 5MB]
Hinrichs, Arne; Riedel, Evamaria O.; Klymiuk, Nikolai; Blutke, Andreas; Kemter, Elisabeth; Laengin, Matthias; Dahlhoff, Maik; Kessler, Barbara; Kurome, Mayuko; Zakhartchenko, Valeri; Jemiller, Eva-Maria; Ayares, David; Bidlingmaier, Martin; Flenkenthaler, Florian; Hrabe de Angelis, Martin; Arnold, Georg J.; Reichart, Bruno; Fröhlich, Thomas und Wolf, Eckhard
(2020):
Growth hormone receptor knockout to reduce the size of donor pigs for preclinical xenotransplantation studies.
In: Xenotransplantation, Vol. 28, No. 2, e12664
Hoesl, Christine; Zanuttigh, Enrica; Fröhlich, Thomas; Philippou-Massier, Julia; Krebs, Stefan; Blum, Helmut und Dahlhoff, Maik
(2020):
The secretome of skin cancer cells activates the mTOR/MYC pathway in healthy keratinocytes and induces tumorigenic properties.
In: Biochimica et Biophysica Acta-Molecular Cell Research, Vol. 1867, No. 8, 118717
Huppertz, Christine; Jager, Benedikt; Wieczorek, Grazyna; Engelhard, Peggy; Oliver, Stephen J.; Bauernfeind, Franz-Georg; Littlewood-Evans, Amanda; Welte, Tobias; Hornung, Veit und Prasse, Antje
(2020):
The NLRP3 inflammasome pathway is activated in sarcoidosis and involved in granuloma formation.
In: European Respiratory Journal, Vol. 55, No. 3, 1900119
Jansma, Marijke; Linke-Winnebeck, Christian; Eustermann, Sebastian; Lammens, Katja; Kostrewa, Dirk; Stakyte, Kristina; Litz, Claudia; Kessler, Brigitte und Hopfner, Karl-Peter
(2020):
Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State.
In: Structure, Vol. 28, No. 1: pp. 83-95
Killinger, Kerstin; Boehm, Miriam; Steinbach, Philine; Hagemann, Goetz; Blueggel, Mike; Jaenen, Karolin; Hohoff, Simone; Bayer, Peter; Herzog, Franz und Westermann, Stefan
(2020):
Auto-inhibition of Mif2/CENP-C ensures centromere-dependent kinetochore assembly in budding yeast.
In: EMBO Journal, Vol. 39, No. 14, e102938
Koepke, Lennart; Winter, Benjamin; Grenzner, Alexander; Regensburger, Kerstin; Engelhart, Susanne; Merwe, Johannes A. van der; Krebs, Stefan; Blum, Helmut; Kirchhoff, Frank und Sparrer, Konstantin M. J.
(2020):
An improved method for high-throughput quantification of autophagy in mammalian cells.
In: Scientific Reports, Vol. 10, No. 1, 12241
[PDF, 6MB]
Kratzat, Hanna; Mackens-Kiani, Timur; Ameismeier, Michael; Potocnjak, Mia; Cheng, Jingdong; Dacheux, Estelle; Namane, Abdelkader; Berninghausen, Otto; Herzog, Franz; Fromont-Racine, Micheline; Becker, Thomas und Beckmann, Roland
(2020):
A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
In: EMBO Journal, Vol. 40, No. 1, e105179
Lampl, Sandra; Janas, Marianne K.; Donakonda, Sainitin; Brugger, Marcus; Lohr, Kerstin; Schneider, Annika; Manske, Katrin; Sperl, Laura E.; Klaeger, Susan; Kuester, Bernhard; Wettmarshausen, Jennifer; Müller, Constanze; Laschinger, Melanie; Hartmann, Daniel; Hueser, Norber; Perocchi, Fabiana; Schmitt-Kopplin, Philippe; Hagn, Franz; Zender, Lars; Hornung, Veit; Borner, Christoph; Pichlmair, Andreas; Kashkar, Hamid; Klingenspor, Martin; Prinz, Marco; Schreiner, Sabrina; Conrad, Marcus; Jost, Philipp J.; Zischka, Hans; Steiger, Katja; Kroenke, Martin; Zehn, Dietmar; Protzer, Ulrike; Heikenwaelder, Mathias; Knolle, Percy A. und Wohlleber, Dirk
(2020):
Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes.
In: Journal of Hepatology, Vol. 73, No. 6: pp. 1347-1359
Latoscha, Andreas; Drexler, David Jan; Al-Bassam, Mahmoud M.; Bandera, Adrian M.; Kaever, Volkhard; Findlay, Kim C.; Witte, Gregor und Tschowri, Natalia
(2020):
c-di-AMP hydrolysis by the phosphodiesterase AtaC promotes differentiation of multicellular bacteria.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 13: pp. 7392-7400
Lauterbach-Riviere, Lise; Bergez, Maiwenn; Moench, Saskia; Qu, Bingqian; Riess, Maximilian; Vondran, Florian W. R.; Liese, Juliane; Hornung, Veit; Urban, Stephan und König, Renate
(2020):
Hepatitis B Virus DNA is a Substrate for the cGAS/STING Pathway but is not Sensed in Infected Hepatocytes.
In: Viruses-Basel, Vol. 12, No. 6, 592
Limbrick, Emilianne M.; Graf, Michael; Derewacz, Dagmara K.; Nguyen, Fabian; Spraggins, Jeffrey M.; Wieland, Maximiliane; Ynigez-Gutierrez, Audrey E.; Reisman, Benjamin J.; Zinshteyn, Boris; McCulloch, Kathryn M.; Iverson, T. M.; Green, Rachel; Wilson, Daniel N. und Bachmann, Brian O.
(2020):
Bifunctional Nitrone-Conjugated Secondary Metabolite Targeting the Ribosome.
In: Journal of the American Chemical Society, Vol. 142, No. 43: pp. 18369-18377
Linder, Andreas; Bauernfried, Stefan; Cheng, Yiming; Albanese, Manuel; Jung, Christophe; Keppler, Oliver T. und Hornung, Veit
(2020):
CARD8 inflammasome activation triggers pyroptosis in human T cells.
In: EMBO Journal, Vol. 39, No. 19, e105071
[PDF, 1MB]
Loregger, Anke; Raaben, Matthijs; Nieuwenhuis, Joppe; Tan, Josephine M. E.; Jae, Lucas T.; Hengel, Lisa G. van den; Hendrix, Sebastian; Berg, Marlene van den; Scheij, Saskia; Song, Ji-Ying; Huijbers, Ivo J.; Kroese, Lona J.; Ottenhoff, Roelof; Weeghel, Michel van; Sluis, Bart van de; Brummelkamp, Thijn und Zelcer, Noam
(2020):
Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism.
In: Nature Communications, Vol. 11, No. 1, 1128
[PDF, 3MB]
Lucienne, Marie; Aguilar-Pimentel, Juan Antonio; Amarie, Oana V.; Becker, Lore; Calzada-Wack, Julia; Silva-Buttkus, Patricia da; Garrett, Lillian; Holter, Sabine M.; Mayer-Kuckuk, Philipp; Rathkolb, Birgit; Rozman, Jan; Spielmann, Nadine; Treise, Irina; Busch, Dirk H.; Klopstock, Thomas; Schmidt-Weber, Carsten; Wolf, Eckhard; Wurst, Wolfgang; Forny, Merima; Mathis, Deborah; Fingerhut, Ralph; Froese, D. Sean; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin und Baumgartner, Matthias R.
(2020):
In-depth phenotyping reveals common and novel disease symptoms in a hemizygous knock-in mouse model (Mut-ko/ki) of mut-type methylmalonic aciduria.
In: Biochimica et Biophysica Acta-Molecular Basis of Disease, Vol. 1866, No. 3, 165622
[PDF, 2MB]
Margos, Gabriele; Fedorova, Natalia; Becker, Noemie S.; Kleinjan, Joyce E.; Marosevic, Durdica; Krebs, Stefan; Hui, Lucia; Fingerle, Volker und Lane, Robert S.
(2020):
Borrelia maritima sp. nov., a novel species of the Borrelia burgdorferi sensu tato complex, occupying a basal position to North American species.
In: International Journal of Systematic and Evolutionary Microbiology, Vol. 70, No. 2: pp. 849-856
Matsuo, Yoshitaka; Tesina, Petr; Nakajima, Shizuka; Mizuno, Masato; Endo, Akinori; Buschauer, Robert; Cheng, Jingdong; Shounai, Okuto; Ikeuchi, Ken; Saeki, Yasushi; Becker, Thomas; Beckmann, Roland und Inada, Toshifumi
(2020):
RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1.
In: Nature Structural & Molecular Biology, Vol. 27, No. 4: pp. 323-332
Messner, Martina; Schmitt, Sabine; Ardelt, Maximilian A.; Fröhlich, Thomas; Müller, Martin; Pein, Helmut; Huber-Cantonati, Petra; Ortler, Carina; König, Lars M.; Zobel, Lena; Koeberle, Andreas; Arnold, Georg J.; Rothenfusser, Simon; Kiemer, Alexandra K.; Gerbes, Alexander L.; Zischka, Hans; Vollmar, Angelika M. und Pachmayr, Johanna
(2020):
Metabolic implication of tigecycline as an efficacious second-line treatment for sorafenib-resistant hepatocellular carcinoma.
In: FASEB Journal, Vol. 34, No. 9: pp. 11860-11882
Michalski, Sebastian; de Oliveira Mann, Carina C.; Stafford, Che A.; Witte, Gregor; Bartho, Joseph; Lammens, Katja; Hornung, Veit und Hopfner, Karl-Peter
(2020):
Structural basis for sequestration and autoinhibition of cGAS by chromatin.
In: Nature, Vol. 587, No. 7835: pp. 678-682
Mukherjee, Somnath; Erramilli, Satchal K.; Ammirati, Mark; Alvarez, Frances J. D.; Fennell, Kimberly F.; Purdy, Michael D.; Skrobek, Blazej M.; Radziwon, Katarzyna; Coukos, John; Kang, Yanyong; Dutka, Przemyslaw; Gao, Xiang; Qiu, Xiayang; Yeager, Mark; Xu, H. Eric; Han, Seungil und Kossiakoff, Anthony A.
(2020):
Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins.
In: Nature Communications, Vol. 11, No. 1, 1598
[PDF, 4MB]
Nuerenberg-Goloub, Elina; Kratzat, Hanna; Heinemann, Holger; Heuer, Andre; Koetter, Peter; Berninghausen, Otto; Becker, Thomas; Tampe, Robert und Beckmann, Roland
(2020):
Molecular analysis of the ribosome recycling factor ABCE1 bound to the 30S post-splitting complex.
In: EMBO Journal, Vol. 39, No. 9, e103788
Osterman, Ilya A.; Wieland, Maximiliane; Maviza, Tinashe P.; Lashkevich, Kseniya A.; Lukianov, Dmitrii A.; Komarova, Ekaterina S.; Zakalyukina, Yuliya V.; Buschauer, Robert; Shiriaev, Dmitrii I.; Leyn, Semen A.; Zlamal, Jaime E.; Biryukov, Mikhail V.; Skvortsov, Dmitry A.; Tashlitsky, Vadim N.; Polshakov, Vladimir I.; Cheng, Jingdong; Polikanov, Yury S.; Bogdanov, Alexey A.; Osterman, Andrei L.; Dmitriev, Sergey E.; Beckmann, Roland; Dontsova, Olga A.; Wilson, Daniel N. und Sergiev, Petr V.
(2020):
Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel.
In: Nature Chemical Biology, Vol. 16, No. 10: pp. 1071-1077
Pinci, Francesca; Gaidt, Moritz M.; Jung, Christophe; Kuut, Gunnar; Jackson, Margaret A.; Bauernfried, Stefan und Hornung, Veit
(2020):
C-tag TNF: a reporter system to study TNF shedding.
In: Journal of Biological Chemistry, Vol. 295, No. 52: pp. 18065-18075
Reinking, Hannah K.; Kang, Hyun-Seo; Götz, Maximilian J.; Li, Hao-Yi; Kieser, Anja; Zhao, Shubo; Acampora, Aleida C.; Weickert, Pedro; Fessler, Evelyn; Jae, Lucas T.; Sattler, Michael und Stingele, Julian
(2020):
DNA Structure-Specific Cleavage of DNA-Protein Crosslinks by the SPRTN Protease.
In: Molecular Cell, Vol. 80, No. 1: pp. 102-113
Renner, Simone; Blutke, Andreas; Clauss, Sebastian; Deeg, Cornelia A.; Kemter, Elisabeth; Merkus, Daphne; Wanke, Rüdiger und Wolf, Eckhard
(2020):
Porcine models for studying complications and organ crosstalk in diabetes mellitus.
In: Cell and Tissue Research, Vol. 380, No. 2: pp. 341-378
Riedel, Evamaria O.; Hinrichs, Arne; Kemter, Elisabeth; Dahlhoff, Maik; Backman, Mattias; Rathkolb, Birgit; Prehn, Cornelia; Adamski, Jerzy; Renner, Simone; Blutke, Andreas; Hrabe de Angelis, Martin; Bidlingmaier, Martin; Schopohl, Jochen; Arnold, Georg J.; Fröhlich, Thomas und Wolf, Eckhard
(2020):
Functional changes of the liver in the absence of growth hormone (GH) action - Proteomic and metabolomic insights from a GH receptor deficient pig model.
In: Molecular Metabolism, Vol. 36, 100978
Schmid, Nina; Missel, Annika; Petkov, Stoyan; Stöckl, Jan B.; Flenkenthaler, Florian; Arnold, Georg J.; Fröhlich, Thomas; Behr, Rüdiger und Mayerhofer, Artur
(2020):
A translational cellular model for the study of peritubular cells of the testis.
In: Reproduction, Vol. 160, No. 2: pp. 259-268
Schmitt, Saskia; Tahk, Siret; Lohner, Alina; Haenel, Gerulf; Maiser, Andreas; Hauke, Martina; Patel, Lubna; Rothe, Maurine; Josenhans, Christine; Leonhardt, Heinrich; Griffioen, Marieke; Deiser, Katrin; Fenn, Nadja C.; Hopfner, Karl-Peter und Subklewe, Marion
(12. November 2020):
Fusion of Bacterial Flagellin to a Dendritic Cell-Targeting αCD40 Antibody Construct Coupled With Viral or Leukemia-Specific Antigens Enhances Dendritic Cell Maturation and Activates Peptide-Responsive T Cells.
In: Frontiers in Immunology, Vol. 11, 602802: pp. 1-16
[PDF, 3MB]
Schnatbaum, Karsten; Solis-Mezarino, Victor; Pokrovsky, Daniil; Schaefer, Frederike; Nagl, Dennis; Hornberger, Lars; Zerweck, Johannes; Knaute, Tobias; Avramova-Nehmer, Julia; Schutkowski, Mike; Hornung, Veit; Wenschuh, Holger; Voelker-Albert, Moritz Carl; Imhof, Axel und Reimer, Ulf
(2020):
New Approaches for Absolute Quantification of Stable-Isotope-Labeled Peptide Standards for Targeted Proteomics Based on a UV Active Tag.
In: Proteomics, Vol. 20, No. 10, 2000007
Schnepf, Max; Ludwig, Claudia; Bandilla, Peter; Ceolin, Stefano; Unnerstall, Ulrich; Jung, Christophe und Gaul, Ulrike
(2020):
Sensitive Automated Measurement of Histone-DNA Affinities in Nucleosomes.
In: Iscience, Vol. 23, No. 2, 100824
Sinha, Niladri K.; Ordureau, Alban; Best, Katharina; Saba, James A.; Zinshteyn, Boris; Sundaramoorthy, Elayanambi; Fulzele, Amit; Garshott, Danielle M.; Denk, Timo; Thoms, Matthias; Paulo, Joao A.; Harper, J. Wade; Bennett, Eric J.; Beckmann, Roland und Green, Rachel
(2020):
EDF1 coordinates cellular responses to ribosome collisions.
In: eLife, Vol. 9, e58828
[PDF, 8MB]
Stöckl, Jan B.; Schmid, Nina; Flenkenthaler, Florian; Drummer, Charis; Behr, Rüdiger; Mayerhofer, Artur; Arnold, Georg J. und Fröhlich, Thomas
(2020):
Proteomic Insights into Senescence of Testicular Peritubular Cells from a Nonhuman Primate Model.
In: Cells, Vol. 9, No. 11, 2498
Thoms, Matthias; Buschauer, Robert; Ameismeier, Michael; Koepke, Lennart; Denk, Timo; Hirschenberger, Maximilian; Kratzat, Hanna; Hayn, Manuel; Mackens-Kiani, Timur; Cheng, Jingdong; Straub, Jan H.; Stürzel, Christina M.; Fröhlich, Thomas; Berninghausen, Otto; Becker, Thomas; Kirchhoff, Frank; Sparrer, Konstantin M. J. und Beckmann, Roland
(2020):
Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
In: Science, Vol. 369, No. 6508: pp. 1249-1255
Trambauer, Johannes; Rodríguez Sarmiento, Rosa María; Fukumori, Akio; Feederle, Regina; Baumann, Karlheinz und Steiner, Harald
(2020):
Aβ43‐producing PS1 FAD mutants cause altered substrate interactions and respond to γ‐secretase modulation.
In: Embo Reports, Vol. 21, No. 1, e47996
[PDF, 1MB]
Watanabe, Reika; Buschauer, Robert; Böhning, Jan; Audagnotto, Martina; Lasker, Keren; Lu, Tsan-Wen; Boassa, Daniela; Taylor, Susan und Villa, Elizabeth
(2020):
The In Situ Structure of Parkinson's Disease-Linked LRRK2.
In: Cell, Vol. 182, No. 6: pp. 1508-1518
Weichmann, Franziska; Hett, Robert; Schepers, Aloys; Ito-Kureha, Taku; Flatley, Andrew; Slama, Kaouthar; Hastert, Florian D.; Angstman, Nicholas B.; Cardoso, M. Cristina; König, Julian; Huettelmaier, Stefan; Dieterich, Christoph; Canzar, Stefan; Helm, Mark; Heissmeyer, Vigo; Feederle, Regina und Meister, Gunter
(2020):
Validation strategies for antibodies targeting modified ribonucleotides.
In: Rna, Vol. 26, No. 10: pp. 1489-1506
Welter, Harald; Herrmann, Carola; Fröhlich, Thomas; Flenkenthaler, Florian; Eubler, Katja; Schorle, Hubert; Nettersheim, Daniel; Mayerhofer, Artur und Müller-Taubenberger, Annette
(2020):
Filamin A Orchestrates Cytoskeletal Structure, Cell Migration and Stem Cell Characteristics in Human Seminoma TCam-2 Cells.
In: Cells, Vol. 9, No. 12, 2563
Weng, Tsai-Hsuan; Steinchen, Wieland; Beatrix, Birgitta; Berninghausen, Otto; Becker, Thomas; Bange, Gert; Cheng, Jingdong und Beckmann, Roland
(2020):
Architecture of the active post-translational Sec translocon.
In: EMBO Journal, Vol. 40, No. 3, e105643
Wolfien, Markus; Klatt, Denise; Salybekov, Amankeldi A.; Ii, Masaaki; Komatsu-Horii, Miki; Gaebel, Ralf; Philippou-Massier, Julia; Schrinner, Eric; Akimaru, Hiroshi; Akimaru, Erika; David, Robert; Garbade, Jens; Gummert, Jan; Haverich, Axel; Hennig, Holger; Iwasaki, Hiroto; Kaminski, Alexander; Kawamoto, Atsuhiko; Klopsch, Christian; Kowallick, Johannes T.; Krebs, Stefan; Nesteruk, Julia; Reichenspurner, Hermann; Ritter, Christian; Stamm, Christof; Tani-Yokoyama, Ayumi; Blum, Helmut; Wolkenhauer, Olaf; Schambach, Axel; Asahara, Takayuki und Steinhoff, Gustav
(2020):
Hematopoietic stem-cell senescence and myocardial repair - Coronary artery disease genotype/phenotype analysis of post-MI myocardial regeneration response induced by CABG/CD133+ bone marrow hematopoietic stem cell treatment in RCT PERFECT Phase 3.
In: Ebiomedicine, Vol. 57, 102862
Yasuda, Sayaka; Tsuchiya, Hikaru; Kaiho, Ai; Guo, Qiang; Ikeuchi, Ken; Endo, Akinori; Arai, Naoko; Ohtake, Fumiaki; Murata, Shigeo; Inada, Toshifumi; Baumeister, Wolfgang; Fernandez-Busnadiego, Ruben; Tanaka, Keiji und Saeki, Yasushi
(2020):
Stress- and ubiquitylation-dependent phase separation of the proteasome.
In: Nature, Vol. 578, No. 7794: pp. 296-300
Yim, Annie; Koti, Prasanna; Bonnard, Adrien; Marchiano, Fabio; Duerrbaum, Milena; Garcia-Perez, Cecilia; Villaveces, Jose; Gamal, Salma; Cardone, Giovanni; Perocchi, Fabiana; Storchova, Zuzana und Habermann, Bianca H.
(2020):
mitoXplorer, a visual data mining platform to systematically analyze and visualize mitochondrial expression dynamics and mutations.
In: Nucleic Acids Research, Vol. 48, No. 2: pp. 605-632
[PDF, 6MB]
Zettler, Silja; Renner, Simone; Kemter, Elisabeth; Hinrichs, Arne; Klymiuk, Nikolai; Backman, Mattias; Riedel, Evamaria Olga; Müller, Christiane; Streckel, Elisabeth; Braun-Reichhart, Christina; Martins, Ana Sofia; Kurome, Mayuko; Kessler, Barbara; Zakhartchenko, Valeri; Flenkenthaler, Florian; Arnold, Georg Josef; Fröhlich, Thomas; Blum, Helmut; Blutke, Andreas; Wanke, Rüdiger und Wolf, Eckhard
(2020):
A decade of experience with genetically tailored pig models for diabetes and metabolic research.
In: Animal Reproduction, Vol. 17, No. 3, e20200064
2019
Akoury, Elias; Ma, Guoli; Demolin, Segolene; Broenner, Cornelia; Zocco, Manuel; Cirilo, Alexandre; Ivic, Nives und Halic, Mario
(2019):
Disordered region of H3K9 methyltransferase Clr4 binds the nucleosome and contributes to its activity.
In: Nucleic Acids Research, Vol. 47, No. 13: pp. 6726-6736
Andersen, Line Lykke; Terczynska-Dyla, Ewa; Mork, Nanna; Scavenius, Carsten; Enghild, Jan J.; Hoening, Klara; Hornung, Veit; Christiansen, Mette; Mogensen, Trine H. und Hartmann, Rune
(2019):
Frequently used bioinformatics tools overestimate the damaging effect of allelic variants.
In: Genes and Immunity, Vol. 20, No. 1: pp. 10-22
Barrio, Santiago; Stuehmer, Thorsten; Da-Via, Matteo; Barrio-Garcia, Clara; Lehners, Nicola; Besse, Andrej; Cuenca, Isabel; Garitano-Trojaola, Andoni; Fink, Severin; Leich, Ellen; Chatterjee, Manik; Driessen, Christoph; Martinez-Lopez, Joaquin; Rosenwald, Andreas; Beckmann, Roland; Bargou, Ralf C.; Braggio, Esteban; Stewart, A. Keith; Raab, Marc S.; Einsele, Hermann und Kortuem, K. Martin
(2019):
Spectrum and functional validation of PSMB5 mutations in multiple myeloma.
In: Leukemia, Vol. 33, No. 2: pp. 447-456
Bastian, Lorenz; Schröder, Michael P.; Eckert, Cornelia; Schlee, Cornelia; Tanchez, Jutta Ortiz; Kaempf, Sebastian; Wagner, Dimitrios L.; Schulze, Veronika; Isaakidis, Konstandina; Lazaro-Navarro, Juan; Haenzelmann, Sonja; James, Alva Rani; Ekici, Arif; Burmeister, Thomas; Schwartz, Stefan; Schrappe, Martin; Horstmann, Martin; Vosberg, Sebastian; Krebs, Stefan; Blum, Helmut; Hecht, Jochen; Greif, Philipp A.; Rieger, Michael A.; Brueggemann, Monika; Goekbuget, Nicola; Neumann, Martin und Baldus, Claudia D.
(2019):
PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia.
In: Leukemia, Vol. 33, No. 8: pp. 1895-1909
Berg, Daniel A.; Su, Yijing; Jimenez-Cyrus, Dennisse; Patel, Aneek; Huang, Nancy; Morizet, David; Lee, Stephanie; Shah, Reeti; Ringeling, Francisca Rojas; Jain, Rajan; Epstein, Jonathan A.; Wu, Qing-Feng; Canzar, Stefan; Ming, Guo-Li; Song, Hongjun und Bond, Allison M.
(2019):
A Common Embryonic Origin of Stem Cells Drives Developmental and Adult Neurogenesis.
In: Cell, Vol. 177, No. 3
Bergez, Maiewenn; Weber, Jakob; Riess, Maximilian; Erdbeer, Alexander; Seifried, Janna; Stanke, Nicole; Munz, Clara; Hornung, Veit; König, Renate und Lindemann, Dirk
(2019):
Insights into Innate Sensing of Prototype Foamy Viruses in Myeloid Cells.
In: Viruses-Basel, Vol. 11, No. 12, 1095
Bernardini, Jonathan P.; Brouwer, Jason M.; Tan, Iris K. L.; Sandow, Jarrod J.; Huang, Shuai; Stafford, Che A.; Bankovacki, Aleksandra; Riffkin, Christopher D.; Wardak, Ahmad Z.; Czabotar, Peter E.; Lazarou, Michael und Dewson, Grant
(2019):
Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy.
In: EMBO Journal, Vol. 38, No. 2, e99916
Cheng, Jingdong; Bassler, Jochen; Fischer, Paulina; Lau, Benjamin; Kellner, Nikola; Kunze, Ruth; Griesel, Sabine; Kallas, Martina; Berninghausen, Otto; Strauss, Daniela; Beckmann, Roland und Hurt, Ed
(2019):
Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.
In: Molecular Cell, Vol. 75, No. 6
Clauss, Sebastian; Bleyer, Christina; Schuettler, Dominik; Tomsits, Philipp; Renner, Simone; Klymiuk, Nikolai; Wakili, Reza; Massberg, Steffen; Wolf, Eckhard und Kaab, Stefan
(2019):
Animal models of arrhythmia: classic electrophysiology to genetically modified large animals.
In: Nature Reviews Cardiology, Vol. 16, No. 8: pp. 457-475
De Marco, Fabio; Willer, Konstantin; Gromann, Lukas B.; Andrejewski, Jana; Hellbach, Katharina; Baehr, Andrea; Dmochewitz, Michaels; Köhler, Thomas; Maack, Hanns-Ingo; Pfeiffer, Franz und Herzen, Julia
(2019):
Contrast-to-noise ratios and thickness-normalized, ventilation-dependent signal levels in dark-field and conventional in vivo thorax radiographs of two pigs.
In: PLOS One
14(6), e0217858
[PDF, 2MB]
Dias, Mariana Castro; Coisne, Caroline; Baden, Pascale; Enzmann, Gaby; Garrett, Lillian; Becker, Lore; Hoelter, Sabine M.; de Angelis, Martin Hrabe; Deutsch, Urban; Engelhardt, Britta; Aguilar-Pimentel, Antonio; Adler, Thure; Busch, Dirk H.; Spielmann, Nadine; Moreth, Kristin; Hans, Wolfgang; Amarie, Oana; Graw, Jochen; Rozman, Jan; Radc, Ildiko; Neff, Frauke; Calzada-Wack, Julia; Rathkolb, Birgit; Wolf, Eckhard; Klopstock, Thomas; Wurst, Wolfgang; Beckers, Johannes; Oestereicher, Manuela; Miller, Gregor; Maier, Holger; Stoeger, Claudia; Leuchtenberger, Stefanie; Gailus-Durner, Valerie und Fuchs, Helmut
(2019):
Claudin-12 is not required for blood-brain barrier tight junction function.
In: Fluids and Barriers of the Cns, Vol. 16, No. 1, 30
[PDF, 3MB]
Duan, Jingyue (Ellie); Shi, Wei; Jue, Nathaniel K.; Jiang, Zongliang; Kuo, Lynn; O'Neill, Rachel; Wolf, Eckhard; Dong, Hong; Zheng, Xinbao; Chen, Jingbo und Tian, Xiuchun (Cindy)
(2019):
Dosage Compensation of the X Chromosomes in Bovine Germline, Early Embryos, and Somatic Tissues.
In: Genome Biology and Evolution, Vol. 11, No. 1: pp. 242-252
Edens, Brittany M.; Vissers, Caroline; Su, Jing; Arumugam, Saravanan; Xu, Zhaofa; Shi, Han; Miller, Nimrod; Ringeling, Francisca Rojas; Ming, Guo-li; He, Chuan; Song, Hongjun und Ma, Yongchao C.
(2019):
FMRP Modulates Neural Differentiation through m(6)A-Dependent mRNA Nuclear Export.
In: Cell Reports, Vol. 28, No. 4
Fecher, Caroline; Trovo, Laura; Müller, Stephan A.; Snaidero, Nicolas; Wettmarshausen, Jennifer; Heink, Sylvia; Ortiz, Oskar; Wagner, Ingrid; Kühn, Ralf; Hartmann, Jana; Karl, Rosa Maria; Konnerth, Arthur; Korn, Thomas; Wurst, Wolfgang; Merkler, Doron; Lichtenthaler, Stefan F.; Perocchi, Fabiana und Misgeld, Thomas
(2019):
Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity.
In: Nature Neuroscience, Vol. 22, No. 10
Fisch, Daniel; Bando, Hironori; Clough, Barbara; Hornung, Veit; Yamamoto, Masahiro; Shenoy, Avinash R. und Frickel, Eva-Maria
(2019):
Human GBP1 is a microbe-specific gatekeeper of macrophage apoptosis and pyroptosis.
In: EMBO Journal, Vol. 38, No. 13, e100926
Fischböck-Halwachs, Josef; Singh, Sylvia; Potocnjak, Mia; Hagemann, Götz; Solis-Mezarino, Victor; Woike, Stephan; Ghodgaonkar-Steger, Medini; Weissmann, Florian; Gallego, Laura D.; Rojas, Julie; Andreani, Jessica; Köhler, Alwin und Herzog, Franz ORCID: https://orcid.org/0000-0001-8270-1449
(2019):
The COMA complex interacts with Cse4 and positions Sli15/Ipl1 at the budding yeast inner kinetochore.
In: eLife, Vol. 8, e42879
[PDF, 6MB]
Gehring, Torben; Erdmann, Tabea; Rahm, Marco; Gras, Carina; Flatley, Andrew; O'Neill, Thomas J.; Woods, Simone; Meininger, Isabel; Karayel, Ozge; Kutzner, Kerstin; Grau, Michael; Shinohara, Hisaaki; Lammens, Katja; Feederle, Regina; Hauck, Stefanie M.; Lenz, Georg und Krappmann, Daniel
(2019):
MALT1 Phosphorylation Controls Activation of T Lymphocytes and Survival of ABC-DLBCL Tumor Cells.
In: Cell Reports, Vol. 29, No. 4
Greulich, Wilhelm; Wagner, Mirko; Gaidt, Moritz M.; Stafford, Che; Cheng, Yiming; Linder, Andreas; Carell, Thomas und Hornung, Veit
(27. November 2019):
TLR8 Is a Sensor of RNase T2 Degradation Products.
In: Cell, Vol. 179, No. 6: pp. 1264-1275
[PDF, 2MB]
Guenther, Saskia D.; Fritsch, Melanie; Seeger, Jens M.; Schiffmann, Lars M.; Snipas, Scott J.; Coutelle, Maria; Kufer, Thomas A.; Higgins, Paul G.; Hornung, Veit; Bernardini, Maria L.; Hoening, Stefan; Kroenke, Martin; Salvesen, Guy S. und Kashkar, Hamid
(2019):
Cytosolic Gram-negative bacteria prevent apoptosis by inhibition of effector caspases through lipopolysaccharide.
In: Nature Microbiology, Vol. 5, No. 2
Gutierrez-Escribano, Pilar; Newton, Matthew D.; Llauro, Aida; Huber, Jonas; Tanasie, Loredana; Davy, Joseph; Aly, Isabel; Aramayo, Ricardo; Montoya, Alex; Kramer, Holger; Stigler, Johannes; Rueda, David S. und Aragon, Luis
(2019):
A conserved ATP- and Scc2/4-dependent activity for cohesin in tethering DNA molecules.
In: Science Advances, Vol. 5, No. 11, eaay6804
Heijink, Anne Margriet; Talens, Francien; Jae, Lucas T.; Gijn, Stephanie E. van; Fehrmann, Rudolf S. N.; Brummelkamp, Thijn R. und Vugt, Marcel A. T. M. van
(2019):
BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity.
In: Nature Communications, Vol. 10, 100
[PDF, 2MB]
Heim, Valentin J.; Stafford, Che A. und Nachbur, Ueli
(2. October 2019):
NOD Signaling and Cell Death.
In: Frontiers in Cell and Developmental Biology, Vol. 7, 208
[PDF, 1MB]
Hoesl, Christine; Fröhlich, Thomas; Hundt, Jennifer E.; Kneitz, Hermann; Goebeler, Matthias; Wolf, Ronald; Schneider, Marlon R. und Dahlhoff, Maik
(2019):
The transmembrane protein LRIG2 increases tumor progression in skin carcinogenesis.
In: Molecular Oncology, Vol. 13, No. 11: pp. 2476-2492
[PDF, 9MB]
Hoss, Florian; Müller, James L.; Ringeling, Francisca Rojas; Rodriguez-Alcazar, Juan F.; Brinkschulte, Rebecca; Seifert, Gerald; Stahl, Rainer; Broderick, Lori; Putnam, Chris D.; Kolodner, Richard D.; Canzar, Stefan; Geyer, Matthias; Hoffman, Hal M. und Latz, Eicke
(2019):
Alternative splicing regulates stochastic NLRP3 activity.
In: Nature Communications, Vol. 10, 3238
[PDF, 1MB]
Hupa, Kristof Johannes; Stein, Kathy; Schneider, Ralf; Lysson, Mariola; Schneiker, Bianca; Hornung, Veit; Latz, Eicke; Iwakura, Yoichiro; Kalff, Jörg C. und Wehner, Sven
(2019):
AIM2 inflammasome-derived IL-1 beta induces postoperative ileus in mice.
In: Scientific Reports, Vol. 9, 10602
[PDF, 1MB]
Iacobucci, Claudio; Piotrowski, Christine; Aebersold, Ruedi; Amaral, Bruno C.; Andrews, Philip; Bernfur, Katja; Borchers, Christoph; Brodie, Nicolas I.; Bruce, James E.; Cao, Yong; Chaignepain, Stephane; Chavez, Juan D.; Claverol, Stephane; Cox, Jürgen; Davis, Trisha; Degliesposti, Gianluca; Dong, Meng-Qiu; Edinger, Nufar; Emanuelsson, Cecilia; Gay, Marina; Götze, Michael; Gomes-Neto, Francisco; Gozzo, Fabio C.; Gutierrez, Craig; Haupt, Caroline; Heck, Albert J. R.; Herzog, Franz; Huang, Lan; Hoopmann, Michael R.; Kalisman, Nir; Klykov, Oleg; Kukacka, Zdenek; Liu, Fan; MacCoss, Michael J.; Mechtler, Karl; Mesika, Ravit; Moritz, Robert L.; Nagaraj, Nagarjuna; Nesati, Victor; Neves-Ferreira, Ana G. C.; Ninnis, Robert; Novak, Petr; O'Reilly, Francis J.; Pelzing, Matthias; Petrotchenko, Evgeniy; Piersimoni, Lolita; Plasencia, Manolo; Pukala, Tara; Rand, Kasper D.; Rappsilber, Juri; Reichmann, Dana; Sailer, Carolin; Sarnowski, Chris P.; Scheltema, Richard A.; Schmidt, Carla; Schriemer, David C.; Shi, Yi; Skehel, J. Mark; Slavin, Moriya; Sobott, Frank; Solis-Mezarino, Victor; Stephanowitz, Heike; Stengel, Florian; Stieger, Christian E.; Trabjerg, Esben; Trnka, Michael; Vilaseca, Marta; Viner, Rosa; Xiang, Yufei; Yilmaz, Sule; Zelter, Alex; Ziemianowicz, Daniel; Leitner, Alexander und Sinz, Andrea
(2019):
First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study.
In: Analytical Chemistry, Vol. 91, No. 11: pp. 6953-6961
Ikeuchi, Ken; Tesina, Petr; Matsuo, Yoshitaka; Sugiyama, Takato; Cheng, Jingdong; Saeki, Yasushi; Tanaka, Keiji; Becker, Thomas; Beckmann, Roland und Inada, Toshifumi
(2019):
Collided ribosomes form a unique structural interface to induce Hel2-driven quality controlpathways.
In: EMBO Journal, Vol. 38, No. 5, e100276
Jensen, Lars R.; Garrett, Lillian; Hoelter, Sabine M.; Rathkolb, Birgit; Racz, Ildiko; Adler, Thure; Prehn, Cornelia; Hans, Wolfgang; Rozman, Jan; Becker, Lore; Aguilar-Pimentel, Juan Antonio; Puk, Oliver; Moreth, Kristin; Dopatka, Monika; Walther, Diego J.; Bohlen und Halbach, Viola von; Rath, Matthias; Delatycki, Martin; Bert, Bettina; Fink, Heidrun; Bluemlein, Katharina; Ralser, Markus; Dijck, Anke van; Kooy, Frank; Stark, Zornitza; Müller, Sabine; Scherthan, Harry; Gecz, Jozef; Wurst, Wolfgang; Wolf, Eckhard; Zimmer, Andreas; Klingenspor, Martin; Graw, Jochen; Klopstock, Thomas; Busch, Dirk; Adamski, Jerzy; Fuchs, Helmut; Gailus-Durner, Valerie; de Angelis, Martin Hrabe; Bohlen und Halbach, Oliver von; Ropers, Hans-Hilger und Kuss, Andreas W.
(2019):
A mouse model for intellectual disability caused by mutations in the X-linked 2 '-O-methyltransferase Ftsj1 gene.
In: Biochimica et Biophysica Acta-Molecular Basis of Disease, Vol. 1865, No. 9: pp. 2083-2093
Kaeshammer, Lisa; Saathoff, Jan-Hinnerk; Lammens, Katja; Gut, Fabian; Bartho, Joseph; Alt, Aaron; Kessler, Brigitte und Hopfner, Karl-Peter
(2019):
Mechanism of DNA End Sensing and Processing by the Mre11-Rad50 Complex.
In: Molecular Cell, Vol. 76, No. 3
Kunzelmann, Karl; Ousingsawat, Jiraporn; Cabrita, Ines; Dousova, Tereza; Baehr, Andrea; Janda, Melanie; Schreiber, Rainer und Benedetto, Roberta
(29. January 2019):
TMEM16A in Cystic Fibrosis: Activating or Inhibiting?
In: Frontiers in Pharmacology, Vol. 10, 3
[PDF, 3MB]
Locatelli, Yann; Forde, Niamh; Blum, Helmut; Graf, Alexander; Piegu, Benoit; Mermillod, Pascal; Wolf, Eckhard; Lonergan, Patrick und Saint-Dizier, Marie
(2019):
Relative effects of location relative to the corpus luteum and lactation on the transcriptome of the bovine oviduct epithelium.
In: BMC Genomics, Vol. 20, 233
Metzger, Eric; Wang, Sheng; Urban, Sylvia; Willmann, Dominica; Schmidt, Andreas; Offermann, Anne; Allen, Anita; Sum, Manuela; Obier, Nadine; Cottard, Felicie; Ulferts, Svenja; Preca, Bogdan-Tiberius; Hermann, Bianca; Maurer, Jochen; Greschik, Holger; Hornung, Veit; Einsle, Oliver; Perner, Sven; Imhof, Axel; Jung, Manfred und Schuele, Roland
(2019):
KMT9 monomethylates histone H4 lysine 12 and controls proliferation of prostate cancer cells.
In: Nature Structural & Molecular Biology, Vol. 26, No. 5
Mezzadra, Riccardo; Bruijn, Marjolein de; Jae, Lucas T.; Gomez-Eerland, Raquel; Duursma, Anja; Scheeren, Ferenc A.; Brummelkamp, Thijn R. und Schumacher, Ton N.
(2019):
SLFN11 can sensitize tumor cells towards IFN-gamma-mediated T cell killing.
In: PLOS One
14(2), e0212053
[PDF, 1MB]
Oberbeckmann, Elisa; Wolff, Michael; Krietenstein, Nils; Heron, Mark; Ellins, Jessica L.; Schmid, Andrea; Krebs, Stefan; Blum, Helmut; Gerland, Ulrich und Korber, Philipp
(2019):
Absolute nucleosome occupancy map for the Saccharomyces cerevisiae genome.
In: Genome Research, Vol. 29, No. 12: pp. 1996-2009
Papp, Sophie M.; Fröhlich, Thomas; Radefeld, Karina; Havlicek, Viterslav; Koesters, Miwako; Yu, Hans; Mayrhofer, Corina; Brem, Gottfried; Arnold, Georg J. und Besenfelder, Urban
(2019):
A novel approach to study the bovine oviductal fluid proteome using transvaginal endoscopy.
In: Theriogenology, Vol. 132: pp. 53-61
Ranjbar, Shahin; Haridas, Viraga; Nambu, Aya; Jasenosky, Luke D.; Sadhukhan, Supriya; Ebert, Thomas S.; Hornung, Veit; Cassell, Gail H.; Falvo, James und Goldfeld, Anne E.
(2019):
Cytoplasmic RNA Sensor Pathways and Nitazoxanide Broadly Inhibit Intracellular Mycobacterium tuberculosis Growth.
In: Iscience, Vol. 22
Regensburger, Adrian P.; Fonteyne, Lina M.; Juengert, Jörg; Wagner, Alexandra L.; Gerhalter, Teresa; Nagel, Armin M.; Heiss, Rafael; Flenkenthaler, Florian; Qurashi, Matthias; Neurath, Markus F.; Klymiuk, Nikolai; Kemter, Elisabeth; Fröhlich, Thomas; Uder, Michael; Woelfle, Joachim; Rascher, Wolfgang; Trollmann, Regina; Wolf, Eckhard; Waldner, Maximilian J. und Knieling, Ferdinand
(2019):
Detection of collagens by multispectral optoacoustic tomography as an imaging biomarker for Duchenne muscular dystrophy.
In: Nature Medicine, Vol. 25, No. 12
Schuller, Jan M.; Birrell, James A.; Tanaka, Hideaki; Konuma, Tsuyoshi; Wulflhorst, Hannes; Cox, Nicholas; Schuller, Sandra K.; Thiemann, Jacqueline; Lubitz, Wolfgang; Setif, Pierre; Ikegamis, Takahisa; Engel, Benjamin D.; Kurisu, Genji und Nowaczyk, Marc M.
(2019):
Structural adaptations of photosynthetic complex I enable ferredoxin-dependent electron transfer.
In: Science, Vol. 363, No. 6424
Shanmuganathan, Vivekanandan; Schiller, Nina; Magoulopoulou, Anastasia; Cheng, Jingdong; Braunger, Katharina; Cymer, Florian; Berninghausen, Otto; Beatrix, Birgitta; Kohno, Kenji; Heijne, Gunnar von und Beckmann, Roland
(2019):
Structural and mutational analysis of the ribosome-arresting human XBP1u.
In: eLife, Vol. 8, e46267
[PDF, 4MB]
Shao, Lulu; Hou, Weizhou; Scharping, Nicole E.; Vendetti, Frank P.; Srivastava, Rashmi; Roy, Chandra Nath; Menk, Ashley V.; Wang, Yiyang; Chauvin, Joe-Marc; Karukonda, Pooja; Thorne, Stephen H.; Hornung, Veit; Zarour, Hassane M.; Bakkenist, Christopher J.; Delgoffe, Greg M. und Sarkar, Saumendra N.
(2019):
IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell.
In: Cancer Immunology Research, Vol. 7, No. 8: pp. 1258-1266
Solga, Roxana; Behrens, Juliane; Ziemann, Anja; Riou, Adrien; Berwanger, Carolin; Becker, Lore; Garrett, Lillian; de Angelis, Martin Hrabe; Fischer, Lisa; Coras, Roland; Barkovits, Katalin; Marcus, Katrin; Mahabir, Esther; Eichinger, Ludwig; Schröder, Rolf; Noegel, Angelika A.; Clemen, Christoph S.; Aguilar-Pimentel, Antonio; Schmidt-Weber, Carsten; Klopstock, Thomas; Adler, Thure; Treisel, Irina; Busch, Dirk H.; Moreth, Kristin; Hoelter, Sabine M.; Zimprich, Annemarie; Wurst, Wolfgang; Amarie, Oana; Graw, Jochen; Rozman, Jan; Calzada-Wack, Julia; Racz, Ildiko; Rathkolb, Birgit; Wolf, Eckhard; Oestereicher, Manuela; Miller, Gregor; Lengger, Christoph; Maier, Holger; Stoeger, Claudia; Leuchtenberger, Stefanie; Gallus-Durner, Valerie und Fuchs, Helmut
(2019):
CRN2 binds to TIMP4 and MMP14 and promotes perivascular invasion of glioblastoma cells.
In: European Journal of Cell Biology, Vol. 98, No. 5-8, UNSP 151046
Sulakhe, Dinanath; D'Souza, Mark; Wang, Sheng; Balasubramanian, Sandhya; Athri, Prashanth; Xie, Bingqing; Canzar, Stefan; Agam, Gady; Gilliam, T. Conrad und Maltsev, Natalia
(2019):
Exploring the functional impact of alternative splicing on human protein isoforms using available annotation sources.
In: Briefings in Bioinformatics, Vol. 20, No. 5: pp. 1754-1768
Sustmann, Claudio; Dickopf, Steffen; Regula, Jörg T.; Kettenberger, Hubert; Molhoj, Michael; Gassner, Christian; Weininger, Diana; Fenn, Sebastian; Manigold, Tobias; Kling, Lothar; Kuenkele, Klaus-Peter; Schwaiger, Manfred; Bossenmaier, Birgit; Griese, Julia J.; Hopfner, Karl-Peter; Graff-Meyer, Alexandra; Stahlberg, Henning; Ringler, Philippe; Lauer, Matthias E.; Brinkmann, Ulrich; Schäfer, Wolfgang und Klein, Christian
(2019):
DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity.
In: Mabs, Vol. 11, No. 8: pp. 1402-1414
Tesina, Petr; Heckel, Elisabeth; Cheng, Jingdong; Fromont-Racine, Micheline; Buschauer, Robert; Kater, Lukas; Beatrix, Birgitta; Berninghausen, Otto; Jacquier, Alain; Becker, Thomas und Beckmann, Roland
(2019):
Structure of the 80S ribosome-Xrn1 nuclease complex.
In: Nature Structural & Molecular Biology, Vol. 26, No. 4
Tesina, Petr; Lessen, Laura N.; Buschauer, Robert; Cheng, Jingdong; Wu, Colin Chih-Chien; Berninghausen, Otto; Buskirk, Allen R.; Becker, Thomas; Beckmann, Roland und Green, Rachel
(2019):
Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts.
In: EMBO Journal, Vol. 39, No. 3, e103365
Vetrivel, Sharmilee; Tiso, Natascia; Kuegler, Andrea; Irmler, Martin; Horsch, Marion; Beckers, Johannes; Hladik, Daniela; Giesert, Florian; Gailus-Durner, Valerie; Fuchs, Helmut; Sabrautzki, Sibylle; Angelis, Martin Hrabe de; Graw, Jochen; Adler, Thure; Treise, Irina; Busch, Dirk H.; Aguilar-Pimentel, Antonio; Ollert, Markus; Götz, Alexander; Amarie, Oana; Stoeger, Tobias; Schulz, Holger; Becker, Lore; Klopstock, Thomas; Schrewe, Anja; Spielmann, Nadine; Bekeredjian, Raffi; Garrett, Lillian; Hoelter, Sabine M.; Zimprich, Annemarie; Wurst, Wolfgang; Mayer-Kuckuk, Philipp; Hans, Wolfgang; Rozman, Jan; Klingenspor, Martin; Neff, Frauke; Silva-Buttkus, Patricia da; Calzada-Wack, Julia; Racz, Ildiko; Zimmer, Andreas; Rathkolb, Birgit; Wolf, Eckhard; Prehn, Cornelia; Adamski, Jerzy; Oestereicher, Manuela; Miller, Gregor; Steinkamp, Ralph; Lengger, Christoph; Maier, Holger; Stoeger, Claudia und Leuchtenberger, Stefanie
(2019):
Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia.
In: Experimental Eye Research, Vol. 188, UNSP 107632
[PDF, 7MB]
West, Alan M.; Rosenbereg, Scott C.; Ur, Sarah N.; Lehmern, Madison K.; Ye, Qiaozhen; Hagemann, Götz; Caballero, Iracema; Uson, Isabel; MacQueen, Amy J.; Herzog, Franz und Corbett, Kevin D.
(2019):
A conserved filamentous assembly underlies the structure of the meiotic chromosome axis.
In: eLife, Vol. 8, e40372
[PDF, 3MB]
Yu, Hans; Hackenbroch, Lena; Meyer, Florian R. L.; Reiser, Judith; Razzazi-Fazeli, Ebrahim; Noebauer, Katharina; Besenfelder, Urban; Vogl, Claus; Brem, Gottfried und Mayrhofer, Corina
(2019):
Identification of Rabbit Oviductal Fluid Proteins Involved in Pre-Fertilization Processes by Quantitative Proteomics.
In: Proteomics, Vol. 19, No. 5, 1800319
Zwarts, Irene; van Zutphen, Tim; Kruit, Janine K.; Liu, Weilin; Oosterveer, Maaike H.; Verkade, Henkjan J.; Uhlenhaut, N. Henriette und Jonker, Johan W.
(2019):
Identification of the fructose transporter GLUT5 (SLC2A5) as a novel target of nuclear receptor LXR.
In: Scientific Reports, Vol. 9, 9299
[PDF, 1MB]
de Sousa-Pereira, Patricia; Abrantes, Joana; Bauernfried, Stefan; Pierini, Virginia; Esteves, Pedro Jose; Keppler, Oliver T.; Pizzato, Massimo; Hornung, Veit; Fackler, Oliver T. und Baldauf, Hanna-Mari
(2019):
The antiviral activity of rodent and lagomorph SERINC3 and SERINC5 is counteracted by known viral antagonists.
In: Journal of General Virology, Vol. 100, No. 2: pp. 278-288
van Emden, Thomas S.; Forn, Marta; Forne, Ignasi; Sarkadi, Zsuzsa; Capella, Matias; Caballero, Lucia Martin; Fischer-Burkart, Sabine; Broenner, Cornelia; Simonetta, Marco; Toczyski, David; Halic, Mario; Imhof, Axel und Braun, Sigurd
(2019):
Shelterin and subtelomeric DNA sequences control nucleosome maintenance and genome stability.
In: EMBO Reports, Vol. 20, No. 1, e47181
2018
Abs, Elisabeth; Poorthuis, Rogier B.; Apelblat, Daniella; Muhammad, Karzan; Pardi, M. Belen; Enke, Leona; Kushinsky, Dahlia; Pu, De-Lin; Eizinger, Max Ferdinand; Conzelmann, Karl-Klaus; Spiegel, Ivo und Letzkus, Johannes J.
(2018):
Learning-Related Plasticity in Dendrite-Targeting Layer 1 Interneurons.
In: Neuron, Vol. 100, No. 3: pp. 684-699
Armacki, Milena; Trugenberger, Anna Katharina; Ellwanger, Ann K.; Eiseler, Tim; Schwerdt, Christiane; Bettac, Lucas; Langgartner, Dominik; Azoitei, Ninel; Halbgebauer, Rebecca; Gross, Rüdiger; Barth, Tabea; Lechel, Andre; Walter, Benjamin M.; Kraus, Johann M.; Wiegreffe, Christoph; Grimm, Johannes; Scheffold, Annika; Schneider, Marlon R.; Peuker, Kenneth; Zeissig, Sebastian; Britsch, Stefan; Rose-John, Stefan; Vettorazzi, Sabine; Wolf, Eckhart; Tannapfel, Andrea; Steinestel, Konrad; Reber, Stefan O.; Walther, Paul; Kestler, Hans A.; Radermacher, Peter; Barth, Thomas F. E.; Huber-Lang, Markus; Kleger, Alexander und Seufferlein, Thomas
(2018):
Thirty-eight-negative kinase 1 mediates trauma-induced intestinal injury and multi-organ failure.
In: Journal of Clinical Investigation, Vol. 128, No. 11: pp. 5056-5072
Bauer, Daniela; Meinhold, Sarah; Jakob, Roman P.; Stigler, Johannes; Merkel, Ulrich; Maier, Timm; Rief, Matthias und Zoldak, Gabriel
(2018):
A folding nucleus and minimal ATP binding domain of Hsp70 identified by single-molecule force spectroscopy.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 18: pp. 4666-4671
Braciak, Todd A.; Roskopf, Claudia C.; Wildenhain, Sarah; Fenn, Nadja C.; Schiller, Christian B.; Schubert, Ingo A.; Jacob, Uwe; Honegger, Annemarie; Krupka, Christina; Subklewe, Marion; Spiekermann, Karsten; Hopfner, Karl-Peter; Fey, Georg H.; Aigner, Michael; Krause, Stefan; Mackensen, Andreas und Oduncu, Fuat S.
(2018):
Dual-targeting triplebody 33-16-123 (SPM-2) mediates effective redirected lysis of primary blasts from patients with a broad range of AML subtypes in combination with natural killer cells.
In: Oncoimmunology, Vol. 7, No. 9, e1472195
Braunger, Katharina; Pfeffer, Stefan; Shrimal, Shiteshu; Gilmore, Reid; Berninghausen, Otto; Mandon, Elisabet C.; Becker, Thomas; Förster, Friedrich und Beckmann, Roland
(2018):
Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum.
In: Science, Vol. 360, No. 6385: pp. 215-218
Brechtmann, Felix; Mertes, Christian; Matuseviciute, Agne; Yepez, Vicente A.; Avsec, Ziga; Herzog, Maximilian; Bader, Daniel M.; Prokisch, Holger und Gagneur, Julien
(2018):
OUTRIDER: A Statistical Method for Detecting Aberrantly Expressed Genes in RNA Sequencing Data.
In: American Journal of Human Genetics, Vol. 103, No. 6: pp. 907-917
Cheng, Yiming; Jiang, Li; Keipert, Susanne; Zhang, Shuyue; Hauser, Andreas; Graf, Elisabeth; Strom, Tim; Tschöp, Matthias; Jastroch, Martin und Perocchi, Fabiana
(2018):
Prediction of Adipose Browning Capacity by Systematic Integration of Transcriptional Profiles.
In: Cell Reports, Vol. 23, No. 10: pp. 3112-3125
[PDF, 2MB]
Chiang, Jessica J.; Sparrer, Konstantin M. J.; Gent, Michiel van; Laessig, Charlotte; Huang, Teng; Osterrieder, Nikolaus; Hopfner, Karl-Peter und Gack, Michaela U.
(2018):
Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity.
In: Nature Immunology, Vol. 19, No. 1: pp. 53-62
Clemen, Christoph S.; Winter, Lilli; Strucksberg, Karl-Heinz; Berwanger, Carolin; Türk, Matthias; Kornblum, Cornelia; Florin, Alexandra; Aguilar-Pimentel, Juan Antonio; Amarie, Oana Veronica; Becker, Lore; Garrett, Lillian; Hans, Wolfgang; Moreth, Kristin; Neff, Frauke; Pingen, Laura; Rathkolb, Birgit; Rácz, Ildikó; Rozman, Jan; Treise, Irina; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Vorgerd, Matthias; Eichinger, Ludwig und Schröder, Rolf
(2018):
The heterozygous R155C VCP mutation: Toxic in humans! Harmless in mice?
In: Biochemical and Biophysical Research Communications, Vol. 503, No. 4: pp. 2770-2777
Dyar, Kenneth Allen; Hubert, Michael Jean; Mir, Ashfaq Ali; Ciciliot, Stefano; Lutter, Dominik; Greulich, Franziska; Quagliarini, Fabiana; Kleinert, Maximilian; Fischer, Katrin; Eichmann, Thomas Oliver; Wright, Lauren Emily; Paz, Marcia Ivonne Pena; Casarin, Alberto; Pertegato, Vanessa; Romanello, Vanina; Albiero, Mattia; Mazzucco, Sara; Rizzuto, Rosario; Salviati, Leonardo; Biolo, Gianni; Blaauw, Bert; Schiaffino, Stefano und Uhlenhaut, N. Henriette
(2018):
Transcriptional programming of lipid and amino acid metabolism by the skeletal muscle circadian clock.
In: PLOS Biology
16(8), e2005886
[PDF, 22MB]
Eitel, Michael; Francis, Warren R.; Varoqueaux, Frederique; Daraspe, Jean; Osigus, Hans-Jürgen; Krebs, Stefan; Vargas, Sergio; Blum, Helmut; Williams, Gray A.; Schierwater, Bernd und Wörheide, Gert
(2018):
Comparative genomics and the nature of placozoan species.
In: PLOS Biology
16(7), e2005359
[PDF, 9MB]
Ensfelder, Timm T.; Kurz, Matthias Q.; Iwan, Katharina; Geiger, Simon; Matheisl, Sarah; Müller, Markus; Beckmann, Roland und Carell, Thomas
(2018):
ALKBH5-induced demethylation of mono- and dimethylated adenosine.
In: Chemical Communications, Vol. 54, No. 62: pp. 8591-8593
[PDF, 1MB]
Esteves, Pedro J.; Abrantes, Joana; Baldauf, Hanna-Mari; Ben Mohamed, Lbachir; Chen, Yuxing; Christensen, Neil; Gonzalez-Gallego, Javier; Giacani, Lorenzo; Hu, Jiafen; Kaplan, Gilla; Keppler, Oliver T.; Knight, Katherine L.; Kong, Xiang-Peng; Lanning, Dennis K.; Le Pendu, Jacques; Matos, Ana Lemos de; Liu, Jia; Liu, Shuying; Lopes, Ana M.; Lu, Shan; Lukehart, Sheila; Manabe, Yukari C.; Neves, Fabiana; McFadden, Grant; Pan, Ruimin; Peng, Xuwen; Sousa-Pereira, Patricia de; Pinheiro, Ana; Rahman, Masmudur; Ruvoen-Clouet, Natalie; Subbian, Selvakumar; Tunon, Maria Jesus; Loo, Wessel van der; Vaine, Michael; Via, Laura E.; Wang, Shixia und Mage, Rose
(2018):
The wide utility of rabbits as models of human diseases.
In: Experimental and Molecular Medicine, Vol. 50, 66
Fuchs, Helmut; Aguilar-Pimentel, Juan Antonio; Amarie, Oana V.; Becker, Lore; Calzada-Wack, Julia; Cho, Yi-Li; Garrett, Lillian; Hölter, Sabine M.; Irmler, Martin; Kistler, Martin; Kraiger, Markus; Mayer-Kuckuk, Philipp; Moreth, Kristin; Rathkolb, Birgit; Rozman, Jan; Silva Buttkus, Patricia da; Treise, Irina; Zimprich, Annemarie; Gampe, Kristine; Hutterer, Christine; Stoeger, Claudia; Leuchtenberger, Stefanie; Maier, Holger; Miller, Manuel; Scheideler, Angelika; Wu, Moya; Beckers, Johannes; Bekeredjian, Raffi; Brielmeier, Markus; Busch, Dirk H.; Klingenspor, Martin; Klopstock, Thomas; Ollert, Markus; Schmidt-Weber, Carsten; Stoeger, Tobias; Wolf, Eckhard; Wurst, Wolfgang; Yildirim, Ali Oender; Zimmer, Andreas; Gailus-Durner, Valerie und Hrabe de Angelis, Martin
(2018):
Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.
In: Behavioural Brain Research, Vol. 352: pp. 187-196
Git, Kathy C. G. de; Tuijl, Diana C. van; Luijendijk, Mieneke C. M.; Wolterink-Donselaar, Inge G.; Ghanem, Alexander; Conzelmann, Karl-Klaus und Adan, Roger A. H.
(2018):
Anatomical projections of the dorsomedial hypothalamus to the periaqueductal grey and their role in thermoregulation: a cautionary note.
In: Physiological Reports, Vol. 6, No. 14, e13807
[PDF, 4MB]
Gonzales, Natalia M.; Seo, Jungkyun; Cordero, Ana I. Hernandez; St Pierre, Celine L.; Gregory, Jennifer S.; Distler, Margaret G.; Abney, Mark; Canzar, Stefan; Lionikas, Arimantas und Palmer, Abraham A.
(2018):
Genome wide association analysis in a mouse advanced intercross line.
In: Nature Communications, Vol. 9, 5162
[PDF, 1MB]
Hagl, Beate; Spielberger, Benedikt D.; Thoene, Silvia; Bonnal, Sophie; Mertes, Christian; Winter, Christof; Nijman, Isaac J.; Verduin, Shira; Eberherr, Andreas C.; Puel, Anne; Schindler, Detlev; Ruland, Jürgen; Meitinger, Thomas; Gagneur, Julien; Orange, Jordan S.; Gijn, Marielle E. van und Renner, Ellen D.
(2018):
Somatic alterations compromised molecular diagnosis of DOCK8 hyper-IgE syndrome caused by a novel intronic splice site mutation.
In: Scientific Reports, Vol. 8, 16719
[PDF, 3MB]
Herrmann, Monika; Krupka, Christina; Deiser, Katrin; Brauchle, Bettina; Marcinek, Anetta; Wagner, Ana Ogrinc; Rataj, Felicitas; Mocikat, Ralph; Metzeler, Klaus H.; Spiekermann, Karsten; Kobold, Sebastian; Fenn, Nadja C.; Hopfner, Karl-Peter und Subklewe, Marion
(2018):
Bifunctional PD-1 x alpha CD3 x alpha CD33 fusion protein reverses adaptive immune escape in acute myeloid leukemia.
In: Blood, Vol. 132, No. 23: pp. 2484-2494
Hertel, Johannes; Rotter, Markus; Frenzel, Stefan; Zacharias, Helena U.; Krumsiek, Jan; Rathkolb, Birgit; Hrabe de Angelis, Martin; Rabstein, Sylvia; Pallapies, Dirk; Brüning, Thomas; Grabe, Hans J. und Wang-Sattler, Rui
(2018):
Dilution correction for dynamically influenced urinary analyte data.
In: Analytica Chimica Acta, Vol. 1032: pp. 18-31
Hiller, Björn; Hoppe, Anja; Haase, Christa; Hiller, Christina; Schubert, Nadja; Müller, Werner; Reijns, Martin A. M.; Jackson, Andrew P.; Kunkel, Thomas A.; Wenzel, Jörg; Behrendt, Rayk und Roers, Axel
(2018):
Ribonucleotide Excision Repair Is Essential to Prevent Squamous Cell Carcinoma of the Skin.
In: Cancer Research, Vol. 78, No. 20: pp. 5917-5926
Hinrichs, Arne; Kessler, Barbara; Kurome, Mayuko; Blutke, Andreas; Kemter, Elisabeth; Bernau, Maren; Scholz, Armin M.; Rathkolb, Birgit; Renner, Simone; Bultmann, Sebastian; Leonhardt, Heinrich; Hrabe de Angelis, Martin; Nagashima, Hiroshi; Hoeflich, Andreas; Blum, Werner F.; Bidlingmaier, Martin; Wanke, Rüdiger; Dahlhoff, Maik und Wolf, Eckhard
(2018):
Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liver.
In: Molecular Metabolism, Vol. 11: pp. 113-128
[PDF, 3MB]
Holze, Cathleen; Michaudel, Chloe; Mackowiak, Claire; Haas, Darya A.; Benda, Christian; Hubel, Philipp; Pennemann, Friederike L.; Schnepf, Daniel; Wettmarshausen, Jennifer; Braun, Marianne; Leung, Daisy W.; Amarasinghe, Gaya K.; Perocchi, Fabiana; Staeheli, Peter; Ryffel, Bernhard und Pichlmair, Andreas
(2018):
Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway.
In: Nature Immunology, Vol. 19, No. 2: pp. 130-140
Hourfar, Kai; Eberle, Josef; Müller, Markus; Nuebling, C. Micha; Chudy, Michael; Kress, Julia; Guertler, Lutz; Mayr-Wohlfart, Uschi; Schrezenmeier, Hubert; Hellmann, Inke; Luhm, Jürgen; Kraas, Sabine; Ringwald, Jürgen; Gubbe, Knut; Frank, Kerstin; Karl, Andreas; Tonn, Torsten; Jaeger, Maike; Sireis, Walid; Seifried, Erhard und Schmidt, Michael
(2018):
Human immunodeficiency virus 1 dual-target nucleic acid technology improves blood safety: 5 years of experience of the German Red Cross blood donor service Baden-Wiirttemberg-Hessen.
In: Transfusion, Vol. 58, No. 12: pp. 2886-2893
Juerjens, Gerrit; Schuler, Sören M. M.; Kurz, Michael; Petit, Sylvain; Couturier, Cedric; Jeannot, Frederic; Nguyen, Fabian; Wende, Raffael C.; Hammann, Peter E.; Wilson, Daniel N.; Bacque, Eric; Poeverlein, Christoph und Bauer, Armin
(2018):
Total Synthesis and Structural Revision of the Antibiotic Tetrapeptide GE81112A.
In: Angewandte Chemie-International Edition, Vol. 57, No. 37: pp. 12157-12161
Jung, Christophe; Bandilla, Peter; Reutern, Marc von; Schnepf, Max; Rieder, Susanne; Unnerstall, Ulrich und Gaul, Ulrike
(2018):
True equilibrium measurement of transcription factor-DNA binding affinities using automated polarization microscopy.
In: Nature Communications, Vol. 9, 1605
[PDF, 2MB]
Kleinert, Maximilian; Clemmensen, Christoffer; Hofmann, Susanna M.; Moore, Mary C.; Renner, Simone; Woods, Stephen C.; Huypens, Peter; Beckers, Johannes; Hrabe de Angelis, Martin; Schürmann, Annette; Bakhti, Mostafa; Klingenspor, Martin; Heiman, Mark; Cherrington, Alan D.; Ristow, Michael; Lickert, Heiko; Wolf, Eckhard; Havel, Peter J.; Müller, Timo D. und Tschoep, Matthias H.
(2018):
Animal models of obesity and diabetes mellitus.
In: Nature Reviews Endocrinology, Vol. 14, No. 3: pp. 140-162
Komnig, Daniel; Gertz, Karen; Habib, Pardes; Nolte, Kay W.; Meyer, Tareq; Brockmann, Marc A.; Endres, Matthias; Rathkolb, Birgit; Hrabe de Angelis, Martin; Schulz, Jörg B.; Falkenburger, Björn H. und Reich, Arno
(2018):
Faim2 contributes to neuroprotection by erythropoietin in transient brain ischemia.
In: Journal of Neurochemistry, Vol. 145, No. 3: pp. 258-270
Kotlarz, Daniel; Marquardt, Benjamin; Baroy, Tuva; Lee, Way S.; Konnikova, Liza; Hollizeck, Sebastian; Magg, Thomas; Lehle, Anna S.; Walz, Christoph; Borggraefe, Ingo; Hauck, Fabian; Bufler, Philip; Conca, Raffaele; Wall, Sarah M.; Schumacher, Eva M.; Misceo, Doriana; Frengen, Eirik; Bentsen, Beint S.; Uhlig, Holm H.; Hopfner, Karl-Peter; Muise, Aleixo M.; Snapper, Scott B.; Stromme, Petter und Klein, Christoph
(2018):
Human TGF-beta 1 deficiency causes severe inflammatory bowel disease and encephalopathy.
In: Nature Genetics, Vol. 50, No. 3: pp. 344-348
Lavagi, Ilaria; Krebs, Stefan; Simmet, Kilian; Beck, Andrea; Zakhartchenko, Valeri; Wolf, Eckhard und Blum, Helmut
(2018):
Single-cell RNA sequencing reveals developmental heterogeneity of blastomeres during major genome activation in bovine embryos.
In: Scientific Reports, Vol. 8, 4071
[PDF, 1MB]
Lichtenegger, Felix S.; Rothe, Maurine; Schnorfeil, Frauke M.; Deiser, Katrin; Krupka, Christina; Augsberger, Christian; Schlueter, Miriam; Neitz, Julia und Subklewe, Marion
(2018):
Targeting LAG-3 and PD-1 to Enhance T Cell Activation by Antigen-Presenting Cells.
In: Frontiers in Immunology, Vol. 9, 385
[PDF, 1MB]
Linnekamp, Janneke F.; Hooff, Sander R. van; Prasetyanti, Pramudita R.; Kandimalla, Raju; Buikhuisen, Joyce Y.; Fessler, Evelyn; Ramesh, Prashanthi; Lee, Kelly A. S. T.; Bochove, Grehor G. W.; Jong, Johan H. de; Cameron, Kate; Leersum, Ronald van; Rodermond, Hans M.; Franitza, Marek; Nuernberg, Peter; Mangiapane, Laura R.; Wang, Xin; Clevers, Hans; Vermeulen, Louis; Stassi, Giorgio und Medema, Jan Paul
(2018):
Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models.
In: Cell Death and Differentiation, Vol. 25, No. 3: pp. 616-633
Magg, Thomas; Wiebking, Volker; Conca, Raffaele; Krebs, Stefan; Arens, Stefan; Schmid, Irene; Klein, Christoph; Albert, Michael H. und Hauck, Fabian
(2018):
IPEX due to an exon 7 skipping FOXP3 mutation with autoimmune diabetes mellitus cured by selective T-Reg cell engraftment.
In: Clinical Immunology, Vol. 191: pp. 52-58
Matsunari, Hitomi; Watanabe, Masahito; Nakano, Kazuaki; Enosawa, Shin; Umeyama, Kazuhiro; Uchikura, Ayuko; Yashima, Sayaka; Fukuda, Toru; Klymiuk, Nikolai; Kurome, Mayuko; Kessler, Barbara; Wünschd, Annegret; Zakhartchenko, Valeri; Wolf, Eckhard; Hanazono, Yutaka; Nagaya, Masaki; Umezawa, Akihiro; Nakauchi, Hiromitsu und Nagashima, Hiroshi
(2018):
Modeling lethal X-linked genetic disorders in pigs with ensured fertility.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 4: pp. 708-713
Mayer-Wagner, Susanne; Hammerschmid, Florian; Blum, Helmut; Krebs, Stefan; Redeker, Julia I.; Holzapfel, Boris M.; Jansson, Volkmar und Müller, Peter E.
(2018):
Effects of single and combined low frequency electromagnetic fields and simulated microgravity on gene expression of human mesenchymal stem cells during chondrogenesis.
In: Archives of Medical Science, Vol. 14, No. 3: pp. 608-616
[PDF, 207kB]
Pertici, Irene; Bongini, Lorenzo; Melli, Luca; Bianchi, Giulio; Salvi, Luca; Falorsi, Giulia; Squarci, Caterina; Bozo, Tamas; Cojoc, Dan; Kellermayer, Miklos S. Z.; Lombardi, Vincenzo und Bianco, Pasquale
(2018):
A myosin II nanomachine mimicking the striated muscle.
In: Nature Communications, Vol. 9, 3532
[PDF, 1MB]
Renner, Simone; Blutke, Andreas; Dobenecker, Britta; Dhom, Georg; Müller, Timo D.; Finan, Brian; Clemmensen, Christoffer; Bernau, Maren; Novak, Istvan; Rathkolb, Birgit; Senf, Steffanie; Zoels, Susanne; Roth, Mirjam; Götz, Anna; Hofmann, Susanna M.; Hrabe de Angelis, Martin; Wanke, Rüdiger; Kienzle, Ellen; Scholz, Armin M.; DiMarchi, Richard; Ritzmann, Mathias; Tschoep, Matthias H. und Wolf, Eckhard
(2018):
Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Gottingen minipigs.
In: Molecular Metabolism, Vol. 16: pp. 180-190
[PDF, 2MB]
Rozman, Jan; Rathkolb, Birgit; Oestereicher, Manuela A.; Schütt, Christine; Ravindranath, Aakash Chavan; Leuchtenberger, Stefanie; Sharma, Sapna; Kistler, Martin; Willershaeuser, Monja; Brommage, Robert; Meehan, Terrence F.; Mason, Jeremy; Haselimashhadi, Hamed; Hough, Tertius; Mallon, Ann-Marie; Wells, Sara; Santos, Luis; Lelliott, Christopher J.; White, Jacqueline K.; Sorg, Tania; Champy, Marie-France; Bower, Lynette R.; Reynolds, Corey L.; Flenniken, Ann M.; Murray, Stephen A.; Nutter, Lauryl M. J.; Svenson, Karen L.; West, David; Tocchini-Valentini, Glauco P.; Beaudet, Arthur L.; Bosch, Fatima; Braun, Robert B.; Dobbie, Michael S.; Gao, Xiang; Herault, Yann; Moshiri, Ala; Moore, Bret A.; Lloyd, K. C. Kent; McKerlie, Colin; Masuya, Hiroshi; Tanaka, Nobuhiko; Flicek, Paul; Parkinson, Helen E.; Sedlacek, Radislav; Seong, Je Kyung; Wang, Chi-Kuang Leo; Moore, Mark; Brown, Steve D.; Tschoep, Matthias H.; Wurst, Wolfgang; Klingenspor, Martin; Wolf, Eckhard; Beckers, Johannes; Machicao, Fausto; Peter, Andreas; Staiger, Harald; Häring, Hans-Ulrich; Grallert, Harald; Campillos, Monica; Maier, Holger; Fuchs, Helmut; Gailus-Durner, Valerie; Werner, Thomas und Hrabe de Angelis, Martin
(2018):
Identification of genetic elements in metabolism by high-throughput mouse phenotyping.
In: Nature Communications, Vol. 9, 288
[PDF, 2MB]
Ryan, D. P.; Henzel, K. S.; Pearson, B. L.; Siwek, M. E.; Papazoglou, A.; Guo, L.; Paesler, K.; Yu, M.; Müller, R.; Xie, K.; Schröder, S.; Becker, L.; Garrett, L.; Hölter, S. M.; Neff, F.; Racz, I.; Rathkolb, B.; Rozman, J.; Ehninger, G.; Klingenspor, M.; Klopstock, T.; Wolf, E.; Wurst, W.; Zimmer, A.; Fuchs, H.; Gailus-Durner, V.; Hrabe de Angelis, Martin; Sidiropoulou, K.; Weiergräber, M.; Zhou, Y. und Ehninger, D.
(2018):
A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice.
In: Molecular Psychiatry, Vol. 23, No. 5: pp. 1345-1355
Salomone-Stagni, Marco; Bartho, Joseph D.; Kalita, Eeshan; Rejzek, Martin; Field, Robert A.; Bellini, Dom; Walsh, Martin A. und Benini, Stefano
(2018):
Structural and functional analysis of Erwinia amylovora SrlD. The first crystal structure of a sorbitol-6-phosphate 2-dehydrogenase.
In: Journal of Structural Biology, Vol. 203, No. 2: pp. 109-119
Schlauderer, Florian; Seeholzer, Thomas; Desfosses, Ambroise; Gehring, Torben; Strauss, Mike; Hopfner, Karl-Peter; Gutsche, Irina; Krappmann, Daniel und Lammens, Katja
(2018):
Molecular architecture and regulation of BCL10-MALT1 filaments.
In: Nature Communications, Vol. 9, 4041
[PDF, 3MB]
Schmidt, Eva Marina; Lamprecht, Sebastian; Blaj, Cristina; Schaaf, Christian; Krebs, Stefan; Blum, Helmut; Hermeking, Heiko; Jung, Andreas; Kirchner, Thomas und Horst, David
(2018):
Targeting tumor cell plasticity by combined inhibition of NOT CH and MAPK signaling in colon cancer.
In: Journal of Experimental Medicine, Vol. 215, No. 6: pp. 1693-1708
Schwarz, Marianne; Schall, Kevin; Kallis, Eleni; Eustermann, Sebastian; Guariento, Mara; Moldt, Manuela; Hopfner, Karl-Peter und Michaelis, Jens
(2018):
Single-molecule nucleosome remodeling by INO80 and effects of histone tails.
In: Febs Letters, Vol. 592, No. 3: pp. 318-331
Seeholzer, Thomas; Kurz, Susanne; Schlauderer, Florian; Woods, Simone; Gehring, Torben; Widmann, Simon; Lammens, Katja und Krappmann, Daniel
(2018):
BCL10-CARD11 Fusion Mimics an Active CARD11 Seed That Triggers Constitutive BCL10 Oligomerization and Lymphocyte Activation.
In: Frontiers in Immunology, Vol. 9, 2695
[PDF, 3MB]
Sharma, Subhalakshmi; Cermakova, Katerina; Rijck, Jan de; Demeulemeester, Jonas; Fabry, Milan; El Ashkar, Sara; Belle, Siska van; Lepsik, Martin; Tesina, Petr; Duchoslav, Vojtech; Novak, Petr; Hubalek, Martin; Srb, Pavel; Christ, Frauke; Rezacova, Pavlina; Hodges, H. Courtney; Debyser, Zeger und Veverka, Vaclav
(2018):
Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 30, E7053-E7062
Spletter, Maria L.; Barz, Christiane; Yeroslaviz, Assa; Zhang, Xu; Lemke, Sandra B.; Bonnard, Adrien; Brunner, Erich; Cardone, Giovanni; Basler, Konrad; Habermann, Bianca H. und Schnorrer, Frank
(2018):
A transcriptomics resource reveals a transcriptional transition during ordered sarcomere morphogenesis in flight muscle.
In: eLife, Vol. 7, e34058
[PDF, 14MB]
Stoiber, Katharina; Naglo, Olga; Pernpeintner, Carla; Zhang, Siwei; Köberle, Andreas; Ulrich, Melanie; Werz, Oliver; Müller, Rolf; Zahler, Stefan; Lohmüller, Theobald; Feldmann, Jochen und Braig, Simone
(2018):
Targeting de novo lipogenesis as a novel approach in anti-cancer therapy.
In: British Journal of Cancer, Vol. 118, No. 1: pp. 43-51
Surup, Frank; Chauhan, Dhruv; Niggemann, Jutta; Bartok, Eva; Herrmann, Jennifer; Keck, Matthias; Zander, Wiebke; Stadler, Marc; Hornung, Veit und Müller, Rolf
(2018):
Activation of the NLRP3 Inflammasome by Hyaboron, a New Asymmetric Boron-Containing Macrodiolide from the Myxobacterium Hyalangium minutum.
In: ACS Chemical Biology, Vol. 13, No. 10: pp. 2981-2988
Thoms, Matthias; Mitterer, Valentin; Kater, Lukas; Falquet, Laurent; Beckmann, Roland; Kressler, Dieter und Hurt, Ed
(2018):
Suppressor mutations in Rpf2-Rrs1 or Rpl5 bypass the Cgr1 function for pre-ribosomal 5S RNP-rotation.
In: Nature Communications, Vol. 9, 4094
[PDF, 6MB]
Tian, Pengfei; Steward, Annette; Kudva, Renuka; Su, Ting; Shilling, Patrick J.; Nickson, Adrian A.; Hollins, Jeffrey J.; Beckmann, Roland; Heijne, Gunnar von; Clarke, Jane und Best, Robert B.
(2018):
Folding pathway of an Ig domain is conserved on and off the ribosome.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 48, E11284-E11293
Treise, Irina; Huber, Eva M.; Klein-Rodewald, Tanja; Heinemeyer, Wolfgang; Grassmann, Simon A.; Basler, Michael; Adler, Thure; Rathkolb, Birgit; Helming, Laura; Andres, Christian; Klaften, Matthias; Landbrecht, Christina; Wieland, Thomas; Strom, Tim M.; McCoy, Kathy D.; Macpherson, Andrew J.; Wolf, Eckhard; Gröttrup, Marcus; Ollert, Markus; Neff, Frauke; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin; Groll, Michael und Busch, Dirk H.
(2018):
Defective immuno- and thymoproteasome assembly causes severe immunodeficiency.
In: Scientific Reports, Vol. 8, 5975
[PDF, 5MB]
Vogel, Heike; Kamitz, Anne; Hallahan, Nicole; Lebek, Sandra; Schallschmidt, Tanja; Jonas, Wenke; Jaehnert, Markus; Gottmann, Pascal; Zellner, Lisa; Kanzleiter, Timo; Damen, Mareike; Altenhofen, Delsi; Burkhardt, Ralph; Renner, Simone; Dahlhoff, Maik; Wolf, Eckhard; Müller, Timo D.; Blueher, Matthias; Joost, Hans-Georg; Chadt, Alexandra; Al-Hasani, Hadi und Schürmann, Annette
(2018):
A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and Type 2 diabetes.
In: Human Molecular Genetics, Vol. 27, No. 17: pp. 3099-3112
Xie, Kan; Ryan, Devon P.; Pearson, Brandon L.; Henzel, Kristin S.; Neff, Frauke; Vidal, Ramon O.; Hennion, Magali; Lehmann, Isabelle; Schleif, Melvin; Schröder, Susanne; Adler, Thure; Rathkolb, Birgit; Rozman, Jan; Schütz, Anna-Lena; Prehn, Cornelia; Mickael, Michel E.; Weiergraber, Marco; Adamski, Jerzy; Busch, Dirk H.; Ehninger, Gerhard; Matynia, Anna; Jackson, Walker S.; Wolf, Eckhard; Fuchs, Helmut; Gailus-Durner, Valerie; Bonn, Stefan; Hrabe de Angelis, Martin und Ehninger, Dan
(2018):
Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 10, E2348-E2357
[PDF, 2MB]
Yepez, Vicente A.; Kremer, Laura S.; Iuso, Arcangela; Gusic, Mirjana; Kopajtich, Robert; Konarikova, Eliska; Nadel, Agnieszka; Wachutka, Leonhard; Prokisch, Holger und Gagneur, Julien
(2018):
OCR-Stats: Robust estimation and statistical testing of mitochondrial respiration activities using Seahorse XF Analyzer.
In: PLOS One
13(7), e0199938
[PDF, 3MB]
2017
Andreeva, Liudmila; Hiller, Björn; Kostrewa, Dirk; Lässig, Charlotte; Oliveira Mann, Carina C. de; Drexler, David Jan; Maiser, Andreas; Gaidt, Moritz; Leonhardt, Heinrich; Hornung, Veit und Hopfner, Karl-Peter
(2017):
cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders.
In: Nature, Vol. 549, No. 7672: pp. 394-398
Antonopoulos, Alexios; Psarros, Konstantinos; Abdesselem, Mouna; Szolc, Piotr und Baeuerle, Patrick
(2017):
Dr Patrick Baeuerle, MPMCapital, talks with young scientists.
In: Cardiovascular Research, Vol. 113, No. 12, E42-E42
Arduino, Daniela M.; Wettmarshausen, Jennifer; Vais, Horia; Navas-Navarro, Paloma; Cheng, Yiming; Leimpek, Anja; Ma, Zhongming; Delrio-Lorenzo, Alba; Giordano, Andrea; Garcia-Perez, Cecilia; Medard, Guillaume; Kuster, Bernhard; Garcia-Sancho, Javier; Mokranjac, Dejana; Foskett, J. Kevin; Teresa Alonso, M. und Perocchi, Fabiana
(2017):
Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening.
In: Molecular Cell, Vol. 67, No. 4: pp. 711-723
Ayoubian, Hiresh; Fröhlich, Thomas; Pogodski, Dagmar; Flatley, Andrew; Kremmer, Elisabeth; Schepers, Aloys; Feederle, Regina; Arnold, Georg J. und Grässer, Friedrich A.
(2017):
Antibodies against the mono-methylated arginine-glycine repeat (MMA-RG) of the Epstein-Barr virus nuclear antigen 2 (EBNA2) identify potential cellular proteins targeted in viral transformation.
In: Journal of General Virology, Vol. 98, No. 8: pp. 2128-2142
Baejen, Carlo; Andreani, Jessica; Torkler, Phillipp; Battaglia, Sofia; Schwalb, Bjoern; Lidschreiber, Michael; Maier, Kerstin C.; Boltendahl, Andrea; Rus, Petra; Esslinger, Stephanie; Söding, Johannes und Cramer, Patrick
(2017):
Genome-wide Analysis of RNA Polymerase II Termination at Protein-Coding Genes.
In: Molecular Cell, Vol. 66, No. 1: pp. 38-49
Bauersachs, Stefan; Simintiras, Constantine A.; Sturmey, Roger G.; Krebs, Stefan; Bick, Jochen; Blum, Helmut; Wolf, Eckhard; Lonergan, Pat und Forde, Niamh
(2017):
Effect of metabolic status on conceptus-maternal interactions on day 19 in dairy cattle: II. Effects on the endometrial transcriptome.
In: Biology of Reproduction, Vol. 97, No. 3: pp. 413-425
Baum, Rebecca; Sharma, Shruti; Organ, Jason M.; Jakobs, Christopher; Hornung, Veit; Burr, David B.; Marshak-Rothstein, Ann; Fitzgerald, Katherine A. und Gravallese, Ellen M.
(2017):
STING Contributes to Abnormal Bone Formation Induced by Deficiency of DNase II in Mice.
In: Arthritis & Rheumatology, Vol. 69, No. 2: pp. 460-471
Beckert, Bertrand; Abdelshahid, Maha; Schäfer, Heinrich; Steinchen, Wieland; Arenz, Stefan; Berninghausen, Otto; Beckmann, Roland; Bange, Gert; Turgay, Kürsad und Wilson, Daniel N.
(2017):
Structure of the Bacillus subtilis hibernating 100S ribosome reveals the basis for 70S dimerization.
In: Embo Journal, Vol. 36, No. 14: pp. 2061-2072
Bhat, Javaid Y.; Milicic, Goran; Thieulin-Pardo, Gabriel; Bracher, Andreas; Maxwell, Andrew; Ciniawsky, Susanne; Müller-Cajar, Oliver; Engen, John R.; Hartl, F. Ulrich; Wendler, Petra und Hayer-Hartl, Manajit
(2017):
Mechanism of Enzyme Repair by the AAA(+) Chaperone Rubisco Activase.
In: Molecular Cell, Vol. 67, No. 5: pp. 744-756
Blaj, Cristina; Bringmann, Agnes; Schmidt, Eva Marina; Urbischek, Manuela; Lamprecht, Sebastian; Fröhlich, Thomas; Arnold, Georg J.; Krebs, Stefan; Blum, Helmut; Hermeking, Heiko; Jung, Andreas; Kirchner, Thomas und Horst, David
(2017):
ADNP Is a Therapeutically Inducible Repressor of WNT Signaling in Colorectal Cancer.
In: Clinical Cancer Research, Vol. 23, No. 11: pp. 2769-2780
Blutke, Andreas; Renner, Simone; Flenkenthaler, Florian; Backman, Mattias; Häsner, Serena; Kemter, Elisabeth; Ländström, Erik; Braun-Reichhart, Christina; Albl, Barbara; Streckel, Elisabeth; Rathkolb, Birgit; Prehn, Cornelia; Palladini, Alessandra; Grzybek, Michal; Krebs, Stefan; Bauersachs, Stefan; Bähr, Andrea; Brühschwein, Andreas ORCID: https://orcid.org/0000-0002-7833-8031; Deeg, Cornelia A.; Monte, Erica de; Dmochewitz, Michaela; Eberle, Caroline; Emrich, Daniela; Fux, Robert; Groth, Frauke; Gumbert, Sophie; Heitmann, Antonia; Hinrichs, Arne; Kessler, Barbara; Kurome, Mayuko; Leipig-Rudolph, Miriam; Matiasek, Kaspar; Öztürk, Hazal; Otzdorff, Christiane; Reichenbach, Myriam; Reichenbach, Horst Dieter; Rieger, Alexandra; Rieseberg, Birte; Rosati, Marco; Saucedo, Manuel Nicolas; Schleicher, Anna; Schneider, Marlon R.; Simmet, Kilian; Steinmetz, Judith; Übel, Nicole; Zehetmaier, Patrizia; Jung, Andreas; Adamski, Jerzy; Coskun, Ünal; Hrabe de Angelis, Martin; Simmet, Christian; Ritzmann, Mathias; Meyer-Lindenberg, Andrea; Blum, Helmut; Arnold, Georg J.; Fröhlich, Thomas; Wanke, Rüdiger und Wolf, Eckhard
(2017):
The Munich MIDY Pig Biobank - A unique resource for studying organ crosstalk in diabetes.
In: Molecular Metabolism, Vol. 6, No. 8: pp. 931-940
Brockmann, Markus; Blomen, Vincent A.; Nieuwenhuis, Joppe; Stickel, Elmer; Raaben, Matthijs; Bleijerveld, Onno B.; Altelaar, A. F. Maarten; Jae, Lucas T. und Brummelkamp, Thijn R.
(2017):
Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling.
In: Nature, Vol. 546, No. 7657: pp. 307-311
Böttcher, Ralph T.; Veelders, Maik; Rombaut, Pascaline; Faix, Jan; Theodosiou, Marina; Stradal, Theresa E.; Rottner, Klemens; Zent, Roy; Herzog, Franz ORCID: https://orcid.org/0000-0001-8270-1449 und Faessler, Reinhard
(2017):
Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading.
In: Journal of Cell Biology, Vol. 216, No. 11: pp. 3785-3798
Decker, Tim-Michael; Kluge, Michael; Krebs, Stefan; Shah, Nilay; Blum, Helmut; Friedel, Caroline C. und Eick, Dirk
(2017):
Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of small molecule inhibitor JQ1.
In: Scientific Reports, Vol. 7, 1684
[PDF, 1MB]
Douglass, Amelia M.; Kucukdereli, Hakan; Ponserre, Marion; Markovic, Milica; Gründemann, Jan; Strobel, Cornelia; Morales, Pilar L. Alcala; Conzelmann, Karl-Klaus; Lüthi, Andreas und Klein, Rüdiger
(2017):
Central amygdala circuits modulate food consumption through a positive-valence mechanism.
In: Nature Neuroscience, Vol. 20, No. 10: pp. 1384-1394
Eichhorn, S.; Mendoza, A.; Prinzing, A.; Stroh, A.; Xinghai, L.; Polski, M.; Heller, M.; Lahm, H.; Wolf, E.; Lange, R. und Krane, M.
(2017):
Corpuls CPR Generates Higher Mean Arterial Pressure Than LUCAS II in a Pig Model of Cardiac Arrest.
In: Biomed Research international, Vol. 2017, 5470406
[PDF, 2MB]
Engel, Christina; Brügmann, Grethe; Lambing, Silke; Mühlenbeck, Larissa H.; Marx, Samira; Hagen, Christian; Horvath, Dorottya; Goldeck, Marion; Ludwig, Janos; Herzner, Anna-Maria; Drijfhout, Jan W.; Wenzel, Daniela; Coch, Christoph; Tüting, Thomas; Schlee, Martin; Hornung, Veit; Hartmann, Gunther und Boorn, Jasper G. van den
(2017):
RIG-I Resists Hypoxia-Induced Immunosuppression and Dedifferentiation.
In: Cancer Immunology Research, Vol. 5, No. 6: pp. 455-467
Florin, Tanja; Maracci, Cristina; Graf, Michael; Karki, Prajwal; Klepacki, Dorota; Berninghausen, Otto; Beckmann, Roland; Vazquez-Laslop, Nora; Wilson, Daniel N.; Rodnina, Marina V. und Mankin, Alexander S.
(2017):
An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome.
In: Nature Structural & Molecular Biology, Vol. 24, No. 9: pp. 752-757
Florin, Tanja; Maracci, Cristina; Graf, Michael; Karki, Prajwal; Klepacki, Dorota; Rodnina, Marina V.; Wilson, Daniel N.; Vazquez-Laslop, Nora und Mankin, Alexander S.
(2017):
Antimicrobial Peptide Turns the Ribosome into a Release Factor Trap.
In: FASEB Journal, Vol. 31
Gaidt, Moritz M.; Ebert, Thomas S.; Chauhan, Dhruv; Ramshorn, Katharina; Pinci, Francesca; Zuber, Sarah; O'Duill, Fionan; Schmid-Burgk, Jonathan L.; Hoss, Florian; Buhmann, Raymund; Wittmann, Georg; Latz, Eicke; Subklewe, Marion und Hornung, Veit
(2017):
The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3.
In: Cell, Vol. 171, No. 5: pp. 1110-1124
Glaser, Laura V.; Rieger, Simone; Thumann, Sybille; Beer, Sophie; Kuklik-Roos, Cornelia; Martin, Dietmar E.; Maier, Kerstin C.; Harth-Hertle, Marie L.; Grüning, Björn; Backofen, Rolf; Krebs, Stefan; Blum, Helmut; Zimmer, Ralf; Erhard, Florian und Kempkes, Bettina
(2017):
EBF1 binds to EBNA2 and promotes the assembly of EBNA2 chromatin complexes in B cells.
In: PLOS Pathogens
13(10), e1006664
[PDF, 8MB]
Graf, Michael; Mardirossian, Mario; Nguyen, Fabian; Seefeldt, A. Carolin; Guichard, Gilles; Scocchi, Marco; Innis, C. Axel und Wilson, Daniel N.
(2017):
Proline-rich antimicrobial peptides targeting protein synthesis.
In: Natural Product Reports, Vol. 34, No. 7: pp. 702-711
Graf, S. A.; Heppt, M. V.; Krebs, S.; Kammerbauer, C.; Hornig, E.; Strieder, A.; Blum, H. und Berking, C.
(2017):
Peripheral myelin protein 2 is a target gene of the transcription factor SOX10 in melanoma and affects tumor cell invasion.
In: Experimental Dermatology, Vol. 26, No. 3, E91-E92
Heink, Sylvia; Yogev, Nir; Garbers, Christoph; Herwerth, Marina; Aly, Lilian; Gasperi, Christiane; Husterer, Veronika; Croxford, Andrew L.; Möller-Hackbarth, Katja; Bartsch, Harald S.; Sotlar, Karl; Krebs, Stefan; Regen, Tommy; Blum, Helmut; Hemmer, Bernhard; Misgeld, Thomas; Wunderlich, Thomas F.; Hidalgo, Juan; Oulcka, Mohamed; Rose-John, Stefan; Schmidt-Supprian, Marc; Waisman, Ari und Korn, Thomas
(2017):
Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic T(H)17 cells.
In: Nature Immunology, Vol. 18, No. 1: pp. 74-85
Hermanns, C.; Hampl, V.; Holzer, K.; Aigner, A.; Penkava, J.; Frank, N.; Martin, D. E.; Maier, K. C.; Waldburger, N.; Rössler, S.; Goppelt-Struebe, M.; Akrap, I.; Thavamani, A.; Singer, S.; Nordheim, A.; Gudermann, T. und Mühlich, S.
(2017):
The novel MKL target gene myoferlin modulates expansion and senescence of hepatocellular carcinoma.
In: Oncogene, Vol. 36, No. 24: pp. 3464-3476
Herold, Tobias; Jurinovic, V.; Metzeler, K. H.; Batcha, A. M. N.; Bamopoulos, S. A.; Rothenberg-Thurley, M.; Ksienzyk, B.; Hartmann, L.; Greif, P. A.; Phillippou-Massier, J.; Krebs, S.; Blum, H.; Amler, S.; Schneider, S.; Konstandin, N.; Sauerland, M. C.; Berdel, W. E.; Wörmann, B. J.; Subklewe, M.; Fiegl, M.; Bohlander, S. K.; Braess, J.; Hiddemann, W.; Mansmann, Ulrich und Spiekermann, K.
(2017):
Prediction of Primary Refractory Acute Myeloid Leukemia.
In: Annals of Hematology, Vol. 96: S25-S25
Heuer, Andre; Gerovac, Milan; Schmidt, Christian; Trowitzsch, Simon; Preis, Anne; Kötter, Peter; Berninghausen, Otto; Becker, Thomas; Beckmann, Roland und Tampe, Robert
(2017):
Structure of the 40S-ABCE1 post-splitting complex in ribosome recycling and translation initiation.
In: Nature Structural & Molecular Biology, Vol. 24, No. 5: pp. 453-460
Heuer, Andre; Thomson, Emma; Schmidt, Christian; Berninghausen, Otto; Becker, Thomas; Hurt, Ed und Beckmann, Roland
(2017):
Cryo-EM structure of a late pre-40S ribosomal subunit from Saccharomyces cerevisiae.
In: Elife, Vol. 6, e30189
[PDF, 7MB]
Heuser, Christoph; Gotot, Janine; Piotrowski, Eveline Christina; Philipp, Marie-Sophie; Courreges, Christina Johanna Felicia; Otte, Martin Sylvester; Guo, Linlin; Schmid-Burgk, Jonathan Leo; Hornung, Veit; Heine, Annkristin; Knolle, Percy Alexander; Garbi, Natalio; Serfling, Edgar; Evaristo, Cesar; Thaiss, Friedrich und Kurts, Christian
(2017):
Prolonged IKK beta Inhibition Improves Ongoing CTL Antitumor Responses by Incapacitating Regulatory T Cells.
In: Cell Reports, Vol. 21, No. 3: pp. 578-586
Hinkel, Rabea; Höwe, Andrea; Renner, Simone; Ng, Judy; Lee, Seungmin; Klett, Katharina; Kaczmarek, Veronika; Moretti, Alessandra; Laugwitz, Karl-Ludwig; Skroblin, Philipp; Mayr, Manuel; Milting, Hendrik; Dendorfer, Andreas; Reichart, Bruno; Wolf, Eckhard und Kupatt, Christian
(2017):
Diabetes Mellitus-Induced Microvascular Destabilization in the Myocardium.
In: Journal of the American College of Cardiology, Vol. 69, No. 2: pp. 131-143
Hinrichs, A.; Kessler, B.; Kurome, M.; Rathkolb, B.; Blum, W.; Scholz, A.; Bernau, M.; Blutke, A.; Dahlhoff, M. und Wolf, E.
(2017):
Impaired weight gain and disproportionate organ growth, but preserved fertility in growth hormone receptor deficient pigs (Laron syndrome).
In: Reproduction in Domestic Animals, Vol. 52: p. 24
Honrath, Birgit; Matschke, Lina; Meyer, Tammo; Magerhans, Lena; Perocchi, Fabiana; Ganjam, Goutham K.; Zischka, Hans; Krasel, Cornelius; Gerding, Albert; Bakker, Barbara M.; Bünemann, Moritz; Strack, Stefan; Decher, Niels; Culmsee, Carsten und Dolga, Amalia M.
(2017):
SK2 channels regulate mitochondrial respiration and mitochondrial Ca2+ uptake.
In: Cell Death and Differentiation, Vol. 24, No. 5: pp. 761-773
Huter, Paul; Arenz, Stefan; Bock, Lars V.; Graf, Michael; Frister, Jan Ole; Heuer, Andre; Peil, Lauri; Starosta, Agata L.; Wohlgemuth, Ingo; Peske, Frank; Novacek, Jiri; Berninghausen, Otto; GrubMüller, Helmut; Tenson, Tanel; Beckmann, Roland; Rodnina, Marina V.; Vaiana, Andrea C. und Wilson, Daniel N.
(2017):
Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P.
In: Molecular Cell, Vol. 68, No. 3: pp. 515-527
Karakatsani, Andromachi; Marichal, Nicolas; Urban, Severino; Kalamakis, Georgios; Ghanem, Alexander; Schick, Anna; Zhang, Yina; Conzelmann, Karl-Klaus; Rüegg, Markus A.; Berninger, Benedikt; Ruiz de Almodovar, Carmen; Gascon, Sergio und Kröger, Stephan
(2017):
Neuronal LRP4 regulates synapse formation in the developing CNS.
In: Development, Vol. 144, No. 24: pp. 4604-4615
Karlstetter, Marcus; Kopatz, Jens; Aslanidis, Alexander; Shahraz, Anahita; Caramoy, Albert; Linnartz-Gerlach, Bettina; Lin, Yuchen; Lückoff, Anika; Fauser, Sascha; Düker, Katharina; Claude, Janine; Wang, Yiner; Ackermann, Johannes; Schmidt, Tobias; Hornung, Veit; Skerka, Christine; Langmann, Thomas und Neumann, Harald
(2017):
Polysialic acid blocks mononuclear phagocyte reactivity, inhibits complement activation, and protects from vascular damage in the retina.
In: Embo Molecular Medicine, Vol. 9, No. 2: pp. 154-166
Kater, Lukas; Thoms, Matthias; Barrio-Garcia, Clara; Cheng, Jingdong; Ismail, Sherif; Ahmed, Yasar Luqman; Bange, Gert; Kressler, Dieter; Berninghausen, Otto; Sinning, Irmgard; Hurt, Ed und Beckmann, Roland
(2017):
Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
In: Cell, Vol. 171, No. 7: pp. 1599-1610
Kim-Hellmuth, Sarah; Bechheim, Matthias; Pütz, Benno; Mohammadi, Pejman; Nedelec, Yohann; Giangreco, Nicholas; Becker, Jessica; Kaiser, Vera; Fricker, Nadine; Beier, Esther; Boor, Peter; Castel, Stephane E.; Nöthen, Markus M.; Barreiro, Luis B.; Pickrell, Joseph K.; Müller-Myhsok, Bertram; Lappalainen, Tuuli; Schumacher, Johannes und Hornung, Veit
(2017):
Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations.
In: Nature Communications, Vol. 8
[PDF, 1MB]
Kremer, Laura S.; Bader, Daniel M.; Mertes, Christian; Kopajtich, Robert; Pichler, Garwin; Iuso, Arcangela; Haack, Tobias B.; Graf, Elisabeth; Schwarzmayr, Thomas; Terrile, Caterina; Konarikova, Eliska; Repp, Birgit; Kastenmüller, Gabi; Adamski, Jerzy; Lichtner, Peter; Leonhardt, Christoph; Funalot, Benoit; Donati, Alice; Tiranti, Valeria; Lombes, Anne; Jardel, Claude; Glaeser, Dieter; Taylor, Robert W.; Ghezzi, Daniele; Mayr, Johannes A.; Rötig, Agnes; Freisinger, Peter; Distelmaier, Felix; Strom, Tim M.; Meitinger, Thomas; Gagneur, Julien und Prokisch, Holger
(2017):
Genetic diagnosis of Mendelian disorders via RNA sequencing.
In: Nature Communications, Vol. 8, 15824
[PDF, 1MB]
Leoni, Gabriele; Poli, Andrea de; Mardirossian, Mario; Gambato, Stefano; Florian, Fiorella; Venier, Paola; Wilson, Daniel N.; Tossi, Alessandro; Pallavicini, Alberto und Gerdol, Marco
(2017):
Myticalins: A Novel Multigenic Family of Linear, Cationic Antimicrobial Peptides from Marine Mussels (Mytilus spp.).
In: Marine Drugs, Vol. 15, No. 8, 261
[PDF, 7MB]
Leth, Christoph; Varadharajan, Ashok; Mester, Patrick; Fischaleck, Marlis; Rossmanith, Peter; Schmoll, Friedrich und Fink, Maria
(2017):
Matrixlysis, an improved sample preparation method for recovery of Mycobacteria from animal tissue material.
In: PLOS One
12(7), e0181157
[PDF, 2MB]
Margos, G.; Hepner, S.; Mang, C.; Marosevic, D.; Reynolds, S. E.; Krebs, S.; Sing, A.; Derdakova, M.; Reiter, M. A. und Fingerle, V.
(2017):
Lost in plasmids: next generation sequencing and the complex genome of the tick-borne pathogen Borrelia burgdorferi.
In: BMC Genomics
18:422
[PDF, 1MB]
Maroofian, Reza; Riemersma, Moniek; Jae, Lucas T.; Zhianabed, Narges; Willemsen, Marjolein H.; Wissink-Lindhout, Willemijn M.; Willemsen, Michel A.; Brouwer, Arjan P. M. de; Mehrjardi, Mohammad Yahya Vahidi; Ashrafi, Mahmoud Reza; Kusters, Benno; Kleefstra, Tjitske; Jamshidi, Yalda; Nasseri, Mojila; Pfundt, Rolph; Brummelkamp, Thijn R.; Abbaszadegan, Mohammad Reza; Lefeber, Dirk J. und Bokhoven, Hans van
(2017):
B3GALNT2 mutations associated with non-syndromic autosomal recessive intellectual disability reveal a lack of genotype-phenotype associations in the muscular dystrophy-dystroglycanopathies.
In: Genome Medicine
9:118
[PDF, 1MB]
Matsuo, Yoshitaka; Ikeuchi, Ken; Saeki, Yasushi; Iwasaki, Shintaro; Schmidt, Christian; Udagawa, Tsuyoshi; Sato, Fumiya; Tsuchiya, Hikaru; Becker, Thomas; Tanaka, Keiji; Ingolia, Nicholas T.; Beckmann, Roland und Inada, Toshifumi
(2017):
Ubiquitination of stalled ribosome triggers ribosome-associated quality control.
In: Nature Communications, Vol. 8, 159
[PDF, 2MB]
Medugorac, Ivica; Graf, Alexander; Grohs, Cecile; Rothammer, Sophie; Zagdsuren, Yondon; Gladyr, Elena; Zinovieva, Natalia; Barbieri, Johanna; Seichter, Doris; Russ, Ingolf; Eggen, Andre; Hellenthal, Garrett; Brem, Gottfried; Blum, Helmut; Krebs, Stefan und Capitan, Aurélien
(2017):
Whole-genome analysis of introgressive hybridization and characterization of the bovine legacy of Mongolian yaks.
In: Nature Genetics, Vol. 49, No. 3: pp. 470-475
Meyer, K.; Fröhlich, T.; Kösters, M.; Riedel, E.; Fritz, S.; Salvetti, P.; Lonergan, P.; Wolf, E. und Arnold, G.
(2017):
Impact of metabolic status and genetic merit for fertility on proteomic composition of bovine oviduct fluid.
In: Reproduction in Domestic Animals, Vol. 52: p. 36
Mezzadra, Riccardo; Sun, Chong; Jae, Lucas T.; Gomez-Eerland, Raquel; Vries, Evert de; Wu, Wei; Logtenberg, Meike E. W.; Slagter, Maarten; Rozeman, Elisa A.; Hofland, Ingrid; Broeks, Annegien; Horlings, Hugo M.; Wessels, Lodewyk F. A.; Blank, Christian U.; Xiao, Yanling; Heck, Albert J. R.; Borst, Jannie; Brummelkamp, Thijn R. und Schumacher, Ton N. M.
(2017):
Identification of CMTM6 and CMTM4 as PD-L1 protein regulators.
In: Nature, Vol. 549, No. 7670: pp. 106-110
Michel, Margaux; Demel, Carina; Zacher, Benedikt; Schwalb, Björn; Krebs, Stefan; Blum, Helmut; Gagneur, Julien und Cramer, Patrick
(2017):
TT-seq captures enhancer landscapes immediately after T-cell stimulation.
In: Molecular Systems Biology, Vol. 13, No. 3, 920
Mosalaganti, Shyamal; Keller, Jenny; Altenfeld, Anika; Winzker, Michael; Rombaut, Pascaline; Saur, Michael; Petrovic, Arsen; Wehenkel, Annemarie; Wohlgemuth, Sabine; Müller, Franziska; Maffini, Stefano; Bange, Tanja; Herzog, Franz ORCID: https://orcid.org/0000-0001-8270-1449; Waldmann, Herbert; Raunser, Stefan und Musacchio, Andrea
(2017):
Structure of the RZZ complex and molecular basis of its interaction with Spindly.
In: Journal of cell biology, Vol. 216, No. 4: pp. 961-981
[PDF, 4MB]
Mosalaganti, Shyamal; Keller, Jenny; Altenfeld, Anika; Winzker, Michael; Rombaut, Pascaline; Saur, Michael; Petrovic, Arsen; Wehenkel, Annemarie; Wohlgemuth, Sabine; Müller, Franziska; Maffini, Stefano; Bange, Tanja; Herzog, Franz ORCID: https://orcid.org/0000-0001-8270-1449; Waldmann, Herbert; Raunser, Stefan und Musacchio, Andrea
(2017):
Structure of the RZZ complex and molecular basis of its interaction with Spindly.
In: Journal of Cell Biology, Vol. 216, No. 4: pp. 961-981
Nilsson, Ola B.; Nickson, Adrian A.; Hollins, Jeffrey J.; Wickles, Stephan; Steward, Annette; Beckmann, Roland; Heijne, Gunnar von und Clarke, Jane
(2017):
Cotranslational folding of spectrin domains via partially structured states.
In: Nature Structural & Molecular Biology, Vol. 24, No. 3: pp. 221-225
Pachzelt, L.; Krupka, C.; Kischel, R.; Kufer, P.; Köhnke, T.; Polzer, H.; Spiekermann, K.; Hiddemann, W. und Subklewe, M.
(2017):
Costimulation Increases Intracellular Signalling In Bite (R) Antibody Construct Mediated T-Cell Activation.
In: Haematologica, Vol. 102: p. 361
Ponce, Laia Pascual; Fenn, Nadja C.; Moritz, Nadine; Krupka, Christina; Kozik, Jan-Hendrik; Lauber, Kirsten; Subklewe, Marion und Hopfner, Karl-Peter
(2017):
SIRP alpha-antibody fusion proteins stimulate phagocytosis and promote elimination of acute myeloid leukemia cells.
In: Oncotarget, Vol. 8, No. 7: pp. 11284-11301
[PDF, 6MB]
Raaben, Matthijs; Jae, Lucas T.; Herbert, Andrew S.; Kühne, Ana I.; Stubbs, Sarah H.; Chou, Yi-ying; Blomen, Vincent A.; Kirchhausen, Tomas; Dye, John M.; Brummelkamp, Thijn R. und Whelan, Sean P.
(2017):
NRP2 and CD63 Are Host Factors for Lujo Virus Cell Entry.
In: Cell Host & Microbe, Vol. 22, No. 5: pp. 688-696
Rettinger, A.; Broeckl, S.; Fink, M.; Prodinger, W. M.; Blum, H.; Krebs, S.; Domogalla, J.; Just, F.; Gellert, S.; Straubinger, R. K. und Büttner, M.
(2017):
The Region of Difference Four is a Robust Genetic Marker for Subtyping Mycobacteriumcaprae Isolates and is Linked to Spatial Distribution of Three Subtypes.
In: Transboundary and Emerging Diseases, Vol. 64, No. 3: pp. 782-792
Schneider, Constanze; Oellerich, Thomas; Baldauf, Hanna-Mari; Schwarz, Sarah-Marie; Thomas, Dominique; Flick, Robert; Bohnenberger, Hanibal; Kaderali, Lars; Stegmann, Lena; Cremer, Anjali; Martin, Margarethe; Lohmeyer, Julian; Michaelis, Martin; Hornung, Veit; Schliemann, Christoph; Berdel, Wolfgang E.; Hartmann, Wolfgang; Wardelmann, Eva; Comoglio, Federico; Hansmann, Martin-Leo; Yakunin, Alexander F.; Geisslinger, Gerd; Stroebel, Philipp; Ferreiros, Nerea; Serve, Hubert; Keppler, Oliver T. und Cinatl, Jindrich
(2017):
SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia.
In: Nature Medicine, Vol. 23, No. 2: pp. 250-255
Silva, P.; Neumann, M.; Schroeder, M. P.; Vosberg, S.; Schlee, C.; Isaakidis, K.; Ortiz-Tanchez, J.; Fransecky, L. R.; Hartung, T.; Türkmen, S.; Graf, A.; Krebs, S.; Blum, H.; Müller-Tidow, C.; Thiede, C.; Ehninger, G.; Serve, H.; Hecht, J.; Berdel, W. E.; Greif, P. A.; Röllig, C. und Baldus, C. D.
(2017):
Acute myeloid leukemia in the elderly is characterized by a distinct genetic and epigenetic landscape.
In: Leukemia, Vol. 31, No. 7: pp. 1640-1644
Singh, Hari R.; Nardozza, Aurelio P.; Möller, Ingvar R.; Knobloch, Gunnar; Kistemaker, Hans A. V.; Hassler, Markus; Harrer, Nadine; Blessing, Charlotte; Eustermann, Sebastian; Kotthoff, Christiane; Huet, Sebastien; Müller-Planitz, Felix; Filippov, Dmitri V.; Timinszky, Gyula; Rand, Kasper D. und Ladurner, Andreas G.
(2017):
A Poly-ADP-Ribose Trigger Releases the Auto-Inhibition of a Chromatin Remodeling Oncogene.
In: Molecular Cell, Vol. 68, No. 5: pp. 860-871
Slowinska, M.; Nynca, J.; Arnold, G. J.; Fröhlich, T.; Jankowski, J.; Kozlowski, K.; Mostek, A. und Ciereszko, A.
(2017):
Proteomic identification of turkey (Meleagris gallopavo) seminal plasma proteins.
In: Poultry Science, Vol. 96, No. 9: pp. 3422-3435
Su, Ting; Cheng, Jingdong; Sohmen, Daniel; Hedman, Rickard; Berninghausen, Otto; Heijne, Gunnar von; Wilson, Daniel N. und Beckmann, Roland
(2017):
The force-sensing peptide VemP employs extreme compaction and secondary structure formation to induce ribosomal stalling.
In: Elife, Vol. 6, e25642
[PDF, 7MB]
Tants, Jan-Niklas; Fesser, Stephanie; Kern, Thomas; Stehle, Ralf; Geerlof, Arie; Wunderlich, Christoph; Jün, Michael; Hartlmüller, Christoph; Böttcher, Romy; Kunzelmann, Stefan; Lange, Oliver; Kreutz, Christoph; Förstemann, Klaus und Sattler, Michael
(2017):
Molecular basis for asymmetry sensing of siRNAs by the Drosophila Loqs-PD/Dcr-2 complex in RNA interference.
In: Nucleic Acids Research, Vol. 45, No. 21: pp. 12536-12550
Tkatch, Tatiana; Greotti, Elisa; Baranauskas, Gytis; Pendin, Diana; Roy, Soumitra; Nita, Luliaoana I.; Wettmarshausen, Jennifer; Prigge, Matthias; Yizhar, Ofer; Shirihai, Orian S.; Fishman, Daniel; Hershfinkel, Michal; Fleidervish, Ilya A.; Perocchi, Fabiana; Pozzan, Tullio und Sekler, Israel
(2017):
Optogenetic control of mitochondrial metabolism and Ca2+ signaling by mitochondria-targeted opsins.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, No. 26, E5167-E5176
Vosberg, S.; Hartmann, L.; Metzeler, K. H.; Schumacher, D.; Pastore, F.; Bräundl, K.; Zellmeier, E.; Ksienzyk, B.; Konstandin, N. P.; Schneider, S.; Graf, A.; Krebs, S.; Blum, H.; Neumann, M.; Baldus, C. D.; Bohlander, S. K.; Wolf, S.; Hiddemann, W.; Spiekermann, K. und Greif, P. A.
(2017):
Evolutionary Patterns of Cytogenetically Normal Acute Myeloid Leukemia Correlate with Time to Relapse.
In: Annals of Hematology, Vol. 96: S55-S55
Woischke, Christine; Schaaf, Christian W.; Yang, Hui-Min; Vieth, Michael; Veits, Lothar; Geddert, Helene; Märkl, Bruno; Stömmer, Peter; Schaeffer, David F.; Frölich, Matthias; Blum, Helmut; Vosberg, Sebastian; Greif, Philipp A.; Jung, Andreas; Kirchner, Thomas und Horst, David
(2017):
In-depth mutational analyses of colorectal neuroendocrine carcinomas with adenoma or adenocarcinoma components.
In: Modern Pathology, Vol. 30, No. 1: pp. 95-103
Ye, Qiaozhen; Kim, Dong Hyun; Dereli, Ihsan; Rosenberg, Scott C.; Hagemann, Götz; Herzog, Franz ORCID: https://orcid.org/0000-0001-8270-1449; Toth, Attila; Cleveland, Don W. und Corbett, Kevin D.
(2017):
The AAA plus ATPase TRIP13 remodels HORMA domains through N-terminal engagement and unfolding.
In: Embo Journal, Vol. 36, No. 16: pp. 2419-2434
Yi, Chun-Xia; Walter, Marc; Gao, Yuanqing; Pitra, Soledad; Legutko, Beata; Kaelin, Stefanie; Layritz, Clarita; Garcia-Caceres, Cristina; Bielohuby, Maximilian; Bidlingmaier, Martin; Woods, Stephen C.; Ghanem, Alexander; Conzelmann, Karl-Klaus; Stern, Javier E.; Jastroch, Martin und Tschöp, Matthias H.
(2017):
TNF alpha drives mitochondrial stress in POMC neurons in obesity.
In: Nature Communications, Vol. 8, 15143
[PDF, 1MB]
Yoon, Ki-Jun; Ringeling, Francisca Rojas; Vissers, Caroline; Jacob, Fadi; Pokrass, Michael; Jimenez-Cyrus, Dennisse; Su, Yijing; Kim, Nam-Shik; Zhu, Yunhua; Zheng, Lily; Kim, Sunghan; Wang, Xinyuan; Dore, Louis C.; Jin, Peng; Regot, Sergi; Zhuang, Xiaoxi; Canzar, Stefan; He, Chuan; Ming, Guo-li und Song, Hongjun
(2017):
Temporal Control of Mammalian Cortical Neurogenesis by m(6)A Methylation.
In: Cell, Vol. 171, No. 4: pp. 877-889
2016
Albl, Barbara; Haesner, Serena; Braun-Reichhart, Christina; Streckel, Elisabeth; Renner, Simone; Seeliger, Frank; Wolf, Eckhard; Wanke, Rüdiger und Blutke, Andreas
(2016):
Tissue Sampling Guides for Porcine Biomedical Models.
In: Toxicologic Pathology, Vol. 44, No. 3: pp. 414-420
[PDF, 142kB]
Altunkaya, Gülsah Pekgöz; Malvezzi, Francesca; Demianova, Zuzana; Zimniak, Tomasz; Litos, Gabriele; Weissmann, Florian; Mechtler, Karl; Herzog, Franz und Westermann, Stefan
(2016):
CCAN Assembly Configures Composite Binding Interfaces to Promote Cross-Linking of Ndc80 Complexes at the Kinetochore.
In: Current Biology, Vol. 26, No. 17: pp. 2370-2378
Arenz, Stefan; Juette, Manuel F.; Graf, Michael; Nguyen, Fabian; Huter, Paul; Polikanov, Yury S.; Blanchard, Scott C. und Wilson, Daniel N.
(2016):
Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 27: pp. 7527-7532
Barrio-Garcia, Clara; Thoms, Matthias; Flemming, Dirk; Katerl, Lukas; Berninghausenl, Otto; Baßler, Jochen; Beckmann, Roland und Hurt, Ed
(2016):
Architecture of the Rix1-Rea1 checkpoint machinery during pre-60S-ribosome remodeling.
In: Nature Structural & Molecular Biology, Vol. 23, No. 1: pp. 37-44
Bassani-Sternberg, Michal; Bräunlein, Eva; Klar, Richard; Engleitner, Thomas; Sinitcyn, Pavel; Audehm, Stefan; Straub, Melanie; Weber, Julia; Slotta-Huspenina, Julia; Specht, Katja; Martignoni, Marc E.; Werner, Angelika; Hein, Rüdiger; Busch, Dirk H.; Peschel, Christian; Rad, Roland; Cox, Jürgen; Mann, Matthias und Krackhardt, Angela M.
(2016):
Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry.
In: Nature Communications, Vol. 7, 13404
[PDF, 1MB]
Boorn, Jasper G. van den; Jakobs, Christopher; Hagen, Christian; Renn, Marcel; Luiten, Rosalie M.; Melief, Cornelis J. M.; Tüting, Thomas; Garbi, Natalio; Hartmann, Gunther und Hornung, Veit
(2016):
Inflammasome-Dependent Induction of Adaptive NK Cell Memory.
In: Immunity, Vol. 44, No. 6: pp. 1406-1421
Chagin, V. O.; Casas-Delucchi, C. S.; Reinhart, M.; Schermelleh, L.; Markaki, Y.; Maiser, A.; Bolius, J. J.; Bensimon, A.; Fillies, M.; Domaing, P.; Rozanov, Y. M.; Leonhardt, H. und Cardoso, M. C.
(2016):
4D Visualization of replication foci in mammalian cells corresponding to individual replicons.
In: Nature Communications, Vol. 7, 11231
[PDF, 2MB]
Deeg, Cornelia A.; Uhl, Patrizia; Amann, Barbara; Blutke, Andreas; Renner, Simone; Hirmer, Sieglinde; Merl-Pham, Juliane; Sekundo, Walter; Wanke, Ruediger; Wolf, Eckhard und Hauck, Stefanie M.
(2016):
The INSC94Y transgenic pig: a novel model for diabetic retinopathy with macular edema.
In: Investigative Ophthalmology & Visual Science, Vol. 57, No. 12
Deeng, J.; Chan, K. Y.; Sluis, E. O. van der; Berninghausen, O.; Han, W.; Gumbart, J.; Schulten, K.; Beatrix, B. und Beckmann, R.
(2016):
Dynamic Behavior of Trigger Factor on the Ribosome.
In: Journal of Molecular Biology, Vol. 428, No. 18: pp. 3588-3602
Diener, Susanne; Bayer, Sieglinde; Sabrautzki, Sibylle; Wieland, Thomas; Mentrup, Birgit; Przemeck, Gerhard K. H.; Rathkolb, Birgit; Graf, Elisabeth; Hans, Wolfgang; Fuchs, Helmut; Horsch, Marion; Schwarzmayr, Thomas; Wolf, Eckhard; Klopocki, Eva; Jakob, Franz; Strom, Tim M.; Hrabě de Angelis, Martin und Lorenz-Depiereux, Bettina
(2016):
Exome sequencing identifies a nonsense mutation in Fam46a associated with bone abnormalities in a new mouse model for skeletal dysplasia.
In: Mammalian Genome, Vol. 27, No. 3-4: pp. 111-121
Eser, Philipp; Wachutka, Leonhard; Maier, Kerstin C.; Demel, Carina; Boroni, Mariana; Iyer, Srignanakshi; Cramer, Patrick und Gagneur, Julien
(2016):
Determinants of RNA metabolism in the Schizosaccharomyces pombe genome.
In: Molecular Systems Biology, Vol. 12, No. 2, 857
Eser, Philipp; Wachutka, Leonhard; Maier, Kerstin C.; Demel, Carina; Boroni, Mariana; Iyer, Srignanakshi; Cramer, Patrick und Gagneur, Julien
(2016):
Determinants of RNA metabolism in the Schizosaccharomyces pombe genome.
In: Molecular Systems Biology, Vol. 12, No. 2, 857
[PDF, 1MB]
Fenske, Stefanie; Pröbstle, Rasmus; Auer, Franziska; Hassan, Sami; Marks, Vanessa; Pauza, Danius H.; Biel, Martin und Wahl-Schott, Christian
(2016):
Comprehensive multilevel in vivo and in vitro analysis of heart rate fluctuations in mice by ECG telemetry and electrophysiology.
In: Nature Protocols, Vol. 11, No. 1: pp. 61-86
Fernandez-Garcia, Yaiza; Reguera, Juan; Busch, Carola; Witte, Gregor; Sanchez-Ramos, Oliberto; Betzel, Christian; Cusack, Stephen; Günther, Stephan und Reindl, Sophia
(2016):
Atomic Structure and Biochemical Characterization of an RNA Endonuclease in the N Terminus of Andes Virus L Protein.
In: PLOS Pathogens
12(6), e1005635
[PDF, 9MB]
Friese, Alexandra; Faesen, Alex C.; in 't Veld, Pim J. Huis; Fischböck, Josef; Prumbaum, Daniel; Petrovic, Arsen; Raunser, Stefan; Herzog, Franz und Musacchio, Andrea
(2016):
Molecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP and Astrin.
In: Nature Communications, Vol. 7, 11407
[PDF, 6MB]
Gaidt, Moritz M.; Ebert, Thomas S.; Chauhan, Dhruv; Schmidt, Tobias; Schmid-Burgk, Jonathan L.; Rapino, Francesca; Robertson, Avril A. B.; Cooper, Matthew A.; Graf, Thomas und Hornung, Veit
(2016):
Human Monocytes Engage an Alternative Inflammasome Pathway.
In: Immunity, Vol. 44, No. 4: pp. 833-846
Gallego, Laura D.; Ghodgaonkar Steger, Medini; Polyansky, Anton A.; Schubert, Tobias; Zagrovic, Bojan; Zheng, Ning; Clausen, Tim; Herzog, Franz ORCID: https://orcid.org/0000-0001-8270-1449 und Köhler, Alwin
(2016):
Structural mechanism for the recognition and ubiquitination of a single nucleosome residue by Rad6-Bre1.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 38: pp. 10553-10558
[PDF, 1MB]
Gallego, Laura D.; Steger, Medini Ghodgaonkar; Polyansky, Anton A.; Schubert, Tobias; Zagrovic, Bojan; Zheng, Ning; Clausen, Tim; Herzog, Franz und Köhler, Alwin
(2016):
Structural mechanism for the recognition and ubiquitination of a single nucleosome residue by Rad6-Bre1.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 38: pp. 10553-10558
Groß, Christina J.; Mishra, Ritu; Schneider, Katharina S.; Médard, Guillaume; Wettmarshausen, Jennifer; Dittlein, Daniela C.; Shi, Hexin; Gorka, Oliver; Koenig, Paul-Albert; Fromm, Stephan; Magnani, Giovanni; Ćiković, Tamara; Hartjes, Lara; Smollich, Joachim; Robertson, Avril A. B.; Cooper, Matthew A.; Schmidt-Supprian, Marc; Schuster, Michael; Schroder, Kate; Broz, Petr; Traidl-Hoffmann, Claudia; Beutler, Bruce; Kuster, Bernhard; Ruland, Jürgen; Schneider, Sabine; Perocchi, Fabiana und Groß, Olaf
(2016):
K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria.
In: Immunity, Vol. 45, No. 4: pp. 761-773
Gupta, Saumya; Radhakrishnan, Aparna; Nitin, Rachana; Raharja-Liu, Pandu; Lin, Gen; Steinmetz, Lars M.; Gagneur, Julien und Sinha, Himanshu
(2016):
Meiotic Interactors of a Mitotic Gene TAO3 Revealed by Functional Analysis of its Rare Variant.
In: G3-Genes Genomes Genetics, Vol. 6, No. 8: pp. 2255-2263
Hartmann, L.; Dutta, S.; Opatz, S.; Vosberg, S.; Reiter, K.; Leubolt, G.; Metzeler, K. H.; Herold, T.; Bamopoulos, S. A.; Bräundl, K.; Zellmeier, E.; Ksienzyk, B.; Konstandin, N. P.; Schneider, S.; Hopfner, K. P.; Graf, A.; Krebs, S.; Blum, H.; Middeke, J. M.; Stölzel, F.; Thiede, C.; Wolf, S.; Bohlander, S. K.; Preiss, C.; Chen-Wichmann, L.; Wichmann, C.; Sauerland, M. C.; Büchner, T.; Berdel, W. E.; Wörmann, B. J.; Braess, J.; Hiddemann, W.; Spiekermann, K. und Greif, P. A.
(2016):
Frequent recurring mutations disrupt the anti-proliferative function of ZBTB7A in acute myeloid leukemia with t(8;21) translocation.
In: Haematologica, Vol. 101: p. 11
Heuck, Alexander; Schitter-Sollner, Sonja; Suskiewicz, Marcin Jozef; Kurzbauer, Robert; Kley, Juliane; Schleiffer, Alexander; Rombaut, Pascaline; Herzog, Franz und Clausen, Tim
(2016):
Structural basis for the disaggregase activity and regulation of Hsp104.
In: eLife, Vol. 5, e21516
[PDF, 5MB]
Heuck, Alexander; Schitter-Sollner, Sonja; Suskiewicz, Marcin Józef; Kurzbauer, Robert; Kley, Juliane; Schleiffer, Alexander; Rombaut, Pascaline; Herzog, Franz ORCID: https://orcid.org/0000-0001-8270-1449 und Clausen, Tim
(2016):
Structural basis for the disaggregase activity and regulation of Hsp104.
In: eLife, Vol. 5, e21516
[PDF, 5MB]
Hoeflich, Andreas; Reyer, Anja; Ohde, Daniela; Schindler, Nancy; Brenmoehl, Julia; Spitschak, Marion; Langhammer, Martina; Tuchscherer, Armin; Wirthgen, Elisa; Renner-Müller, Ingrid; Wanke, Rüdiger; Metzger, Friedrich; Bielohuby, Maximilian und Wolf, Eckhard
(2016):
Dissociation of somatic growth, time of sexual maturity, and life expectancy by overexpression of an RGD-deficient IGFBP-2 variant in female transgenic mice.
In: Aging Cell, Vol. 15, No. 1: pp. 111-117
[PDF, 355kB]
Hons, Michael T.; in't Veld, Pim J. Huis; Kaesler, Jan; Rombaut, Pascaline; Schleiffer, Alexander; Herzog, Franz; Stark, Holger und Peters, Jan-Michael
(2016):
Topology and structure of an engineered human cohesin complex bound to Pds5B.
In: Nature Communications, Vol. 7, 12523
[PDF, 2MB]
Huber, Wolfgang; Huber, Toni; Baum, Stephan; Franzen, Michael; Schmidt, Christian; Stadlbauer, Thomas; Beitz, Analena; Schmid, Roland M. und Schmid, Sebastian
(2016):
Sodium Bicarbonate Prevents Contrast-Induced Nephropathy in Addition to Theophylline: A Randomized Controlled Trial.
In: Medicine, Vol. 95, No. 21, e3720
[PDF, 362kB]
Jae, Lucas T.; Blomen, Vincent A.; Raaben, Matthijs; Majek, Peter; Herbert, Andrew S.; Brockmann, Markus; Nieuwenhuis, Joppe; Carette, Jan E.; Saftig, Paul; Whelan, Sean P.; Dye, John M.; Superti-Furga, Giulio; Colinge, Jacques und Brummelkamp, Thijn R.
(2016):
Ultra-deep genome mutagenesis in haploid human cells.
In: Glycobiology, Vol. 26, No. 12: p. 1378
Jakob, Leonhard; Treiber, Thomas; Treiber, Nora; Gust, Alexander; Kramm, Kevin; Hansen, Kerrin; Stotz, Mathias; Wankerl, Ludwig; Herzog, Franz; Hannus, Stefan; Grohmann, Dina und Meister, Gunter
(2016):
Structural and functional insights into the fly microRNA biogenesis factor Loquacious.
In: Rna, Vol. 22, No. 3: pp. 383-396
Jäckel, Carsten; Nogueira, Melanie Schmitt; Ehni, Nadja; Kraus, Christiane; Ranke, Julius; Dohmann, Maike; Noessner, Elfriede und Nelson, Peter J.
(2016):
A vector platform for the rapid and efficient engineering of stable complex transgenes.
In: Scientific Reports, Vol. 6, 34365
[PDF, 1MB]
Kaya, Emine; Doxzen, Kevin W.; Knoll, Kilian R.; Wilson, Ross C.; Strutt, Steven C.; Kranzusch, Philip J. und Doudna, Jennifer A.
(2016):
A bacterial Argonaute with noncanonical guide RNA specificity.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 15: pp. 4057-4062
Kedrov, Alexej; Wickles, Stephan; Crevenna, Alvaro H.; Sluis, Eli O. van der; Buschauer, Robert; Berninghausen, Otto; Lamb, Don C. und Beckmann, Roland
(2016):
Structural Dynamics of the YidC:Ribosome Complex during Membrane Protein Biogenesis.
In: Cell Reports, Vol. 17, No. 11: pp. 2943-2954
[PDF, 5MB]
Kiosze-Becker, Kristin; Ori, Alessandro; Gerovac, Milan; Heuer, Andre; Nürenberg-Goloub, Elina; Rashid, Umar Jan; Becker, Thomas; Beckmann, Roland; Beck, Martin und Tampé, Robert
(2016):
Structure of the ribosome post-recycling complex probed by chemical cross-linking and mass spectrometry.
In: Nature Communications, Vol. 7, 13248
[PDF, 2MB]
Kornprobst, Markus; Turk, Martin; Kellner, Nikola; Cheng, Jingdong; Flemming, Dirk; Kos-Braun, Isabelle; Kos, Martin; Thoms, Matthias; Berninghausen, Otto; Beckmann, Roland und Hurt, Ed
(2016):
Architecture of the 90S Pre-ribosome: A Structural View on the Birth of the Eukaryotic Ribosome.
In: Cell, Vol. 166, No. 2: pp. 380-393
Kourtzelis, Ioannis; Kotlabova, Klara; Lim, Jong-Hyung; Mitroulis, Ioannis; Ferreira, Anaisa; Chen, Lan-Sun; Gercken, Bettina; Steffen, Anja; Kemter, Elisabeth; Klotzsche-von Ameln, Anne; Waskow, Claudia; Hosur, Kavita; Chatzigeorgiou, Antonios; Ludwig, Barbara; Wolf, Eckhard; Hajishengallis, George und Chavakis, Triantafyllos
(2016):
Developmental endothelial locus-1 modulates platelet-monocyte interactions and instant blood-mediated inflammatory reaction in islet transplantation.
In: Thrombosis and Haemostasis, Vol. 115, No. 4: pp. 781-788
Kovacs, Izabella; Holzmeister, Christian; Wirtz, Markus; Geerlof, Arie; Fröhlich, Thomas; Römling, Gaby; Kuruthukulangarakoola, Gitto T.; Linster, Eric; Hell, Rüdiger; Arnold, Georg J.; Durner, Joerg und Lindermayr, Christian
(2016):
ROS-Mediated Inhibition of S-nitrosoglutathione Reductase Contributes to the Activation of Anti-oxidative Mechanisms.
In: Frontiers in Plant Science, Vol. 7, 1669
[PDF, 3MB]
Krapp, Christian; Hotter, Dominik; Gawanbacht, Ali; McLaren, Paul J.; Kluge, Silvia F.; Stürzel, Christina M.; Mack, Katharina; Reith, Elisabeth; Engelhart, Susanne; Ciuffi, Angela; Hornung, Veit; Sauter, Daniel; Telenti, Amalio und Kirchhoff, Frank
(2016):
Guanylate Binding Protein (GBP) 5 Is an Interferon-Inducible Inhibitor of HIV-1 Infectivity.
In: Cell Host & Microbe, Vol. 19, No. 4: pp. 504-514
Liu, Yahui; Petrovic, Arsen; Rombaut, Pascaline; Mosalaganti, Shyamal; Keller, Jenny; Raunser, Stefan; Herzog, Franz und Musacchio, Andrea
(2016):
Insights from the reconstitution of the divergent outer kinetochore of Drosophila melanogaster.
In: Open Biology, Vol. 6, No. 2, 150236
[PDF, 3MB]
Liu, Yahui; Petrovic, Arsen; Rombaut, Pascaline; Mosalaganti, Shyamal; Keller, Jenny; Raunser, Stefan; Herzog, Franz ORCID: https://orcid.org/0000-0001-8270-1449 und Musacchio, Andrea
(2016):
Insights from the reconstitution of the divergent outer kinetochore of Drosophila melanogaster.
In: Open biology, Vol. 6, No. 2, 150236
[PDF, 3MB]
Paijo, Jennifer; Döring, Marius; Spanier, Julia; Grabski, Elena; Nooruzzaman, Mohammed; Schmidt, Tobias; Witte, Gregor; Messerle, Martin; Hornung, Veit; Kaever, Volkhard und Kalinke, Ulrich
(2016):
cGAS Senses Human Cytomegalovirus and Induces Type I Interferon Responses in Human Monocyte-Derived Cells.
In: PLOS Pathogens
12(4), e1005546
[PDF, 1MB]
Petrovic, Arsen; Keller, Jenny; Liu, Yahui; Overlack, Katharina; John, Juliane; Dimitrova, Yoana N.; Jenni, Simon; Gerwen, Suzan van; Stege, Patricia; Wohlgemuth, Sabine; Rombaut, Pascaline; Herzog, Franz; Harrison, Stephen C.; Vetter, Ingrid R. und Musacchio, Andrea
(2016):
Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores.
In: Cell, Vol. 167, No. 4: pp. 1028-1040
Petrovic, Arsen; Keller, Jenny; Liu, Yahui; Overlack, Katharina; John, Juliane; Dimitrova, Yoana N.; Jenni, Simon; van Gerwen, Suzan; Stege, Patricia; Wohlgemuth, Sabine; Rombaut, Pascaline; Herzog, Franz ORCID: https://orcid.org/0000-0001-8270-1449; Harrison, Stephen C.; Vetter, Ingrid R. und Musacchio, Andrea
(2016):
Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores.
In: Cell, Vol. 167, No. 4, e15: pp. 1028-1040
[PDF, 6MB]
Poli, Jérôme; Gerhold, Christian-Benedikt; Tosi, Alessandro; Hustedt, Nicole; Seeber, Andrew; Sack, Ragna; Herzog, Franz; Pasero, Philippe; Shimada, Kenji; Hopfner, Karl-Peter und Gasser, Susan M.
(2016):
Mec1, INO80, and the PAF1 complex cooperate to limit transcription replication conflicts through RNAPII removal during replication stress.
In: Genes & Development, Vol. 30, No. 3: pp. 337-354
Prunetti, Laurence; Graf, Michael; Blaby, Ian K.; Peil, Lauri; Makkay, Andrea M.; Starosta, Agata L.; Papke, R. Thane; Oshima, Tairo; Wilson, Daniel N. und de Crécy-Lagard, Valérie
(2016):
Deciphering the Translation Initiation Factor 5A Modification Pathway in Halophilic Archaea.
In: Archaea - An International Microbiological Journal, 7316725
[PDF, 2MB]
Pépin, Genevieve; Ferrand, Jonathan; Höning, Klara; Jayasekara, W. Samantha N.; Cain, Jason E.; Behlke, Mark A.; Gough, Daniel J.; Williams, Bryan R. G.; Hornung, Veit und Gantier, Michael P.
(2016):
Cre-dependent DNA recombination activates a STING-dependent innate immune response.
In: Nucleic Acids Research, Vol. 44, No. 11: pp. 5356-5364
[PDF, 1MB]
Raetz, St.; Schmidt, T. O. B.; Czesla, S.; Klocová, T.; Holmes, L.; Errmann, R.; Kitze, M.; Fernández, M.; Sota, A.; Briceño, C.; Hernández, J.; Downes, J. J.; Dimitrov, D. P.; Kjurkchieva, D.; Radeva, V.; Wu, Z.-Y.; Zhou, X.; Takahashi, H.; Henych, T.; Seeliger, M.; Mugrauer, M.; Adam, Ch.; Marka, C.; Schmidt, J. G.; Hohle, M. M.; Ginski, Ch.; Pribulla, T.; Trepl, L.; Moualla, M.; Pawellek, N.; Gelszinnis, J.; Buder, S.; Masda, S.; Maciejewski, G. und Neuhäuser, R.
(2016):
YETI observations of the young transiting planet candidate CVSO 30 b.
In: Monthly Notices of the Royal Astronomical Society, Vol. 460, No. 3: pp. 2834-2852
Reess, T. J.; Rus, O. G.; Schmidt, R.; de Reus, M. A.; Zaudig, M.; Wagner, G.; Zimmer, C.; Heuvel, M. P. van den und Koch, K.
(2016):
Connectomics-based structural network alterations in obsessive-compulsive disorder.
In: Translational Psychiatry, Vol. 6, e882
[PDF, 1MB]
Riechers, Birte; Maes, Florine; Akoury, Elias; Semin, Benoit; Gruner, Philipp und Baret, Jean-Christophe
(2016):
Surfactant adsorption kinetics in microfluidics.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 41: pp. 11465-11470
Schmidt, Christian; Becker, Thomas; Heuer, Andre; Braunger, Katharina; Shanmuganathan, Vivekanandan; Pech, Markus; Berninghausen, Otto; Wilson, Daniel N. und Beckmann, Roland
(2016):
Structure of the hypusinylated eukaryotic translation factor eIF-5A bound to the ribosome.
In: Nucleic Acids Research, Vol. 44, No. 4: pp. 1944-1951
[PDF, 3MB]
Schmidt, Christian; Kowalinski, Eva; Shanmuganathan, Vivekanandan; Defenouillere, Quentin; Braunger, Katharina; Heuer, Andre; Pech, Markus; Namane, Abdelkader; Berninghausen, Otto; Fromont-Racine, Micheline; Jacquier, Alain; Conti, Elena; Becker, Thomas und Beckmann, Roland
(2016):
The cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase complex.
In: Science, Vol. 354, No. 6318: pp. 1431-1433
Schwalb, Björn; Michel, Margaux; Zacher, Benedikt; Frühauf, Katja; Demel, Carina; Tresch, Achim; Gagneur, Julien und Cramer, Patrick
(2016):
TT-seq maps the human transient transcriptome.
In: Science, Vol. 352, No. 6290: pp. 1225-1228
Seefeldt, A. Carolin; Graf, Michael; Pérébaskine, Natacha; Nguyen, Fabian; Arenz, Stefan; Mardirossian, Mario; Scocchi, Marco; Wilson, Daniel N. und Innis, C. Axel
(2016):
Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome.
In: Nucleic Acids Research, Vol. 44, No. 5: pp. 2429-2438
Steward, Annette; Nilsson, Ola B.; Nickson, Adrian A.; Hollins, Jeffrey J.; Wickles, Stephan; Marsden, Andrew; Mendonca, Carolina; Beckmann, Roland; Heijne, Gunnar von und Clarke, Jane
(2016):
Cotranslational folding studies of spectrin and Ig-like domains show folding occurs close to the ribosome.
In: Protein Science, Vol. 25: pp. 107-108
Stützer, Alexandra; Liokatis, Stamatios; Kiesel, Anja; Schwarzer, Dirk; Sprangers, Remco; Söding, Johannes; Selenko, Philipp und Fischle, Wolfgang
(2016):
Modulations of DNA Contacts by Linker Histones and Post-translational Modifications Determine the Mobility and Modifiability of Nucleosomal H3 Tails.
In: Molecular Cell, Vol. 61, No. 2: pp. 247-259
Tanaka, Mayuki; Sotta, Naoyuki; Yamazumi, Yusuke; Yamashita, Yui; Miwa, Kyoko; Murota, Katsunori; Chiba, Yukako; Hirai, Masami Yokota; Akiyama, Tetsu; Onouchi, Hitoshi; Naito, Satoshi und Fujiwara, Toru
(2016):
The Minimum Open Reading Frame, AUG-Stop, Induces Boron-Dependent Ribosome Stalling and mRNA Degradation.
In: Plant Cell, Vol. 28, No. 11: pp. 2830-2849
Trapphoff, T.; Heiligentag, M.; Dankert, D.; Demond, H.; Deutsch, D.; Fröhlich, T.; Arnold, G. J.; Grümmer, R.; Horsthemke, B. und Eichenlaub-Ritter, U.
(2016):
Postovulatory aging affects dynamics of mRNA, expression and localization of maternal effect proteins, spindle integrity and pericentromeric proteins in mouse oocytes.
In: Human Reproduction, Vol. 31, No. 1: pp. 133-149
Trapphoff, Tom; Heiligentag, Martyna; Simon, Jenny; Staubach, Nora; Seidel, Thorsten; Otte, Kathrin; Fröhlich, Thomas; Arnold, Georg J. und Eichenlaub-Ritter, Ursula
(2016):
Improved cryotolerance and developmental potential of in vitro and in vivo matured mouse oocytes by supplementing with a glutathione donor prior to vitrification.
In: Molecular Human Reproduction, Vol. 22, No. 12: pp. 867-881
Vos, Seychelle M.; Pöllmann, David; Caizzi, Livia; Hofmann, Katharina B.; Rombaut, Pascaline; Zimniak, Tomasz; Herzog, Franz und Cramer, Patrick
(2016):
Architecture and RNA binding of the human negative elongation factor.
In: eLife, Vol. 5, e14981
[PDF, 6MB]
Vos, Seychelle M.; Pöllmann, David; Caizzi, Livia; Hofmann, Katharina B.; Rombaut, Pascaline; Zimniak, Tomasz; Herzog, Franz ORCID: https://orcid.org/0000-0001-8270-1449 und Cramer, Patrick
(2016):
Architecture and RNA binding of the human negative elongation factor.
In: eLife, Vol. 5, e14981
[PDF, 11MB]
Wales, Pauline; Schuberth, Christian E.; Aufschnaiter, Roland; Fels, Johannes; García-Aguilar, Ireth; Janning, Annette; Dlugos, Christopher P.; Schäfer-Herte, Marco; Klingner, Christoph; Wälte, Mike; Kuhlmann, Julian; Menis, Ekaterina; Kang, Laura Hockaday; Maier, Kerstin C.; Hou, Wenya; Russo, Antonella; Higgs, Henry N.; Pavenstädt, Hermann; Vogl, Thomas; Roth, Johannes; Qualmann, Britta; Kessels, Michael M.; Martin, Dietmar E.; Mulder, Bela und Wedlich-Söldner, Roland
(2016):
Calcium-mediated actin reset (CaAR) mediates acute cell adaptations.
In: eLife, Vol. 5, e19850
[PDF, 4MB]
Weir, John R.; Faesen, Alex C.; Klare, Kerstin; Petrovic, Arsen; Basilico, Federica; Fischböck, Josef; Pentakota, Satyakrishna; Keller, Jenny; Pesenti, Marion E.; Pan, Dongqing; Vogt, Doro; Wohlgemuth, Sabine; Herzog, Franz ORCID: https://orcid.org/0000-0001-8270-1449 und Musacchio, Andrea
(2016):
Insights from biochemical reconstitution into the architecture of human kinetochores.
In: Nature, Vol. 537, 7619: pp. 249-253
Weir, John R.; Faesen, Alex C.; Klare, Kerstin; Petrovic, Arsen; Basilico, Federica; Fischböck, Josef; Pentakota, Satyakrishna; Keller, Jenny; Pesenti, Marion E.; Pan, Dongqing; Vogt, Doro; Wohlgemuth, Sabine; Herzog, Franz ORCID: https://orcid.org/0000-0001-8270-1449 und Musacchio, Andrea
(2016):
Insights from biochemical reconstitution into the architecture of human kinetochores.
In: Nature, Vol. 537, No. 7619: pp. 249-253
[PDF, 7MB]
Wissel, Sebastian; Kieser, Anja; Yasugi, Tetsuo; Duchek, Peter; Roitinger, Elisabeth; Gokcezade, Joseph; Steinmann, Victoria; Gaul, Ulrike; Mechtler, Karl; Förstemann, Klaus; Knoblich, Jürgen A. und Neumüller, Ralph A.
(2016):
A Combination of CRISPR/Cas9 and Standardized RNAi as a Versatile Platform for the Characterization of Gene Function.
In: G3 - Genes Genomes Genetics, Vol. 6, No. 8: pp. 2467-2478
[PDF, 3MB]
Xu, Shuting; Ducroux, Aurelie; Ponnurangam, Aparna; Franz, Sergej; Vieyres, Gabrielle; Müsken, Mathias; Zillinger, Thomas; Malassa, Angelina; Ewald, Ellen; Hornung, Veit; Barchet, Winfried; Häussler, Susanne; Pietschmann, Thomas und Goffinet, Christine
(2016):
cGAMP transfers intercellularly via HIV-1 Env-mediated cell-cell fusion sites and triggers an innate immune response in primary target cells.
Frontiers of Retrovirology Conference 2016, Erlangen, Germany, Montag, 12. September bis Mittwoch, 14. September 2016.
Retrovirology.
Vol. 13, No. Suppl. 1, P64
BioMed Central.
[PDF, 3MB]
Xu, Shuting; Ducroux, Aurélie; Ponnurangam, Aparna; Vieyres, Gabrielle; Franz, Sergej; Müsken, Mathias; Zillinger, Thomas; Malassa, Angelina; Ewald, Ellen; Hornung, Veit; Barchet, Winfried; Häussler, Susanne; Pietschmann, Thomas und Goffinet, Christine
(2016):
cGAS-Mediated Innate Immunity Spreads Intercellularly through HIV-1 Env-Induced Membrane Fusion Sites.
In: Cell Host & Microbe, Vol. 20, No. 4: pp. 443-457
Yamamoto, Hiroshi; Wittek, Daniela; Gupta, Romi; Qin, Bo; Ueda, Takuya; Krause, Roland; Yamamoto, Kaori; Albrecht, Renate; Pech, Markus und Nierhaus, Knud H.
(2016):
70S-scanning initiation is a novel and frequent initiation mode of ribosomal translation in bacteria.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 9, E1180-E1189
2015
Butryn, Agata; Schuller, Jan M.; Stoehr, Gabriele; Runge-Wollmann, Petra; Förster, Friedrich; Auble, David T. und Hopfner, Karl-Peter
(2015):
Structural basis for recognition and remodeling of the TBP:DNA:NC2 complex by Mot1.
In: eLife, Vol. 4, e07432
[PDF, 3MB]
Kock, Malte; Nunes, Maria M.; Hemann, Matthias; Kube, Sebastian; Dohmen, R. Jürgen; Herzog, Franz; Ramos, Paula C. und Wendler, Petra
(2015):
Proteasome assembly from 15S precursors involves major conformational changes and recycling of the Pba1-Pba2 chaperone.
In: Nature Communications, Vol. 6, 6123
[PDF, 2MB]
Laessig, Charlotte; Matheisl, Sarah; Sparrer, Konstantin M. J.; Mann, Carina C. de Oliveira; Moldt, Manuela; Patel, Jenish R.; Goldeck, Marion; Hartmann, Gunther; Garcia-Sastre, Adolfo; Hornung, Veit; Conzelmann, Karl-Klaus; Beckmann, Roland und Hopfner, Karl-Peter
(2015):
ATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA.
In: eLife, Vol. 4, e10859
[PDF, 2MB]
Nilsson, Ola B.; Hedman, Rickard; Marino, Jacopo; Wickles, Stephan; Bischoff, Lukas; Johansson, Magnus; Müller-Lucks, Annika; Trovato, Fabio; Puglisi, Joseph D.; O'Brien, Edward P.; Beckmann, Roland und Heijne, Gunnar von
(2015):
Cotranslational Protein Folding inside the Ribosome Exit Tunnel.
In: Cell Reports, Vol. 12, No. 10: pp. 1533-1540
[PDF, 2MB]
Pfeffer, Stefan; Burbaum, Laura; Unverdorben, Pia; Pech, Markus; Chen, Yuxiang; Zimmermann, Richard; Beckmann, Roland und Foerster, Friedrich
(2015):
Structure of the native Sec61 protein-conducting channel.
In: Nature Communications, Vol. 6, 8403
[PDF, 1MB]
Sluis, Eli O. van der; Bauerschmitt, Heike; Becker, Thomas; Mielke, Thorsten; Frauenfeld, Jens; Berninghausen, Otto; Neupert, Walter; Herrmann, Johannes M. und Beckmann, Roland
(2015):
Parallel Structural Evolution of Mitochondrial Ribosomes and OXPHOS Complexes.
In: Genome Biology and Evolution, Vol. 7, No. 5: pp. 1235-1251
[PDF, 1MB]
Sohmen, Daniel; Chiba, Shinobu; Shimokawa-Chiba, Naomi; Innis, C. Axel; Berninghausen, Otto; Beckmann, Roland; Ito, Koreaki und Wilson, Daniel N.
(2015):
Structure of the Bacillus subtilis 70S ribosome reveals the basis for species-specific stalling.
In: Nature Communications, Vol. 6, 6941
[PDF, 2MB]
2014
Böttcher, Romy; Hollmann, Manuel; Merk, Karin; Nitschko, Volker; Obermaier, Christina; Philippou-Massier, Julia; Wieland, Isabella; Gaul, Ulrike und Förstemann, Klaus
(2014):
Efficient chromosomal gene modification with CRISPR/cas9 and PCR-based homologous recombination donors in cultured Drosophila cells.
In: Nucleic Acids Research, Vol. 42, No. 11, e89
Eser, Philipp; Demel, Carina; Maier, Kerstin C.; Schwalb, Björn; Pirkl, Nicole; Martin, Dietmar E.; Cramer, Patrick und Tresch, Achim
(2014):
Periodic mRNA synthesis and degradation co-operate during cell cycle gene expression.
In: Molecular Systems Biology, Vol. 10, No. 1
Heger, Klaus; Fierens, Kaat; Vahl, J. Christoph; Aszodi, Attila; Peschke, Katrin; Schenten, Dominik; Hammad, Hamida; Beyaert, Rudi; Saur, Dieter; Loo, Geert van; Roers, Axel; Lambrecht, Bart N.; Kool, Mirjam und Schmidt-Supprian, Marc
(2014):
A20-Deficient Mast Cells Exacerbate Inflammatory Responses In Vivo.
In: PLOS Biology
12(1), e1001762
[PDF, 2MB]
Hernando, Henar; Islam, Abul B. M. M. K.; Rodriguez-Ubreva, Javier; Forne, Ignasi; Ciudad, Laura; Imhof, Axel; Shannon-Lowe, Claire und Ballestar, Esteban
(2014):
Epstein-Barr virus-mediated transformation of B cells induces global chromatin changes independent to the acquisition of proliferation.
In: Nucleic Acids Research, Vol. 42, No. 1: pp. 249-263
Mühlbacher, Wolfgang; Sainsbury, Sarah; Hemann, Matthias; Hantsche, Merle; Neyer, Simon; Herzog, Franz und Cramer, Patrick
(2014):
Conserved architecture of the core RNA polymerase II initiation complex.
In: Nature Communications, Vol. 5, 4310
[PDF, 854kB]
Pfeffer, Stefan; Dudek, Johanna; Gogala, Marko; Schorr, Stefan; Linxweiler, Johannes; Lang, Sven; Becker, Thomas; Beckmann, Roland; Zimmermann, Richard und Foerster, Friedrich
(2014):
Structure of the mammalian oligosaccharyl-transferase complex in the native ER protein translocon.
In: Nature Communications, Vol. 5, 3072
Preis, Anne; Heuer, Andre; Barrio-Garcia, Clara; Hauser, Andreas ORCID: https://orcid.org/0000-0002-3997-7252; Eyler, Daniel E.; Berninghausen, Otto; Green, Rachel; Becker, Thomas und Beckmann, Roland
(2014):
Cryoelectron Microscopic Structures of Eukaryotic Translation Termination Complexes Containing eRF1-eRF3 or eRF1-ABCE1.
In: Cell Reports, Vol. 8, No. 1: pp. 59-65
[PDF, 2MB]
Runge, Simon; Sparrer, Konstantin M. J.; Lässig, Charlotte; Hembach, Katharina; Baum, Alina; Garcia-Sastre, Adolfo; Söding, Johannes; Conzelmann, Karl-Klaus und Hopfner, Karl-Peter
(2014):
In Vivo Ligands of MDA5 and RIG-I in Measles Virus-Infected Cells.
In: PLOS Pathogens
10(4), e1004081
[PDF, 1MB]
Schäfer, Matthias; Willrodt, Ann-Helen; Kurinna, Svitlana; Link, Andrea S.; Farwanah, Hany; Geusau, Alexandra; Gruber, Florian; Sorg, Olivier; Huebner, Aaron J.; Roop, Dennis R.; Sandhoff, Konrad; Saurat, Jean-Hilaire; Tschachler, Erwin; Schneider, Marlon R.; Langbein, Lutz; Bloch, Wilhelm; Beer, Hans-Dietmar und Werner, Sabine
(2014):
Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice.
In: Embo Molecular Medicine, Vol. 6, No. 4: pp. 442-457
[PDF, 3MB]
Sydow, Jasmin F.; Lipsmeier, Florian; Larraillet, Vincent; Hilger, Maximiliane; Mautz, Björn; Mølhøj,, Michael; Kuentzer, Jan; Klostermann, Stefan; Schoch, Jürgen; Voelger, Hans R.; Regula, Jörg T.; Cramer, Patrick; Papadimitriou, Apollon und Kettenberger, Hubert
(2014):
Structure-Based Prediction of Asparagine and Aspartate Degradation Sites in Antibody Variable Regions.
In: PLOS ONE
9(6), e100736
[PDF, 1MB]
Wickles, Stephan; Singharoy, Abhishek; Andreani, Jessica; Seemayer, Stefan; Bischoff, Lukas; Berninghausen, Otto; Soeding, Johannes; Schulten, Klaus; Sluis, Eli O. van der und Beckmann, Roland
(2014):
A structural model of the active ribosome-bound membrane protein insertase YidC.
In: eLife, Vol. 3, e03035
[PDF, 3MB]
2013
Lammens, Alfred; Baehner, Monika; Kohnert, Ulrich; Niewoehner, Jens; Proff, Leopold von; Schraeml, Michael; Lammens, Katja und Hopfner, Karl-Peter
(2013):
Crystal Structure of Human TWEAK in Complex with the Fab Fragment of a Neutralizing Antibody Reveals Insights into Receptor Binding.
In: PLOS ONE
8(5), e62697
[PDF, 1MB]
2012
Mohr, Hermine; Mohr, Christian A.; Schneider, Marlon R.; Scrivano, Laura; Adler, Barbara; Kraner-Scheiber, Simone; Schnieke, Angelika; Dahlhoff, Maik; Wolf, Eckhard; Koszinowski, Ulrich H. und Ruzsics, Zsolt
(2012):
Cytomegalovirus replicon-based regulation of gene expression in vitro and in vivo.
In: PLOS Pathogens
8(6), e1002728
[PDF, 2MB]
Niederberger, Theresa; Etzold, Stefanie; Lidschreiber, Michael; Maier, Kerstin C.; Martin, Dietmar E.; Fröhlich, Holger; Cramer, Patrick und Tresch, Achim
(2012):
MC EMiNEM maps the interaction landscape of the Mediator.
In: PLOS Computational Biology
8(6), e1002568
[PDF, 775kB]
2011
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1991
1988
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1983
1982
1980
Braunitzer, Gerdard; Schrank, Barbara; Stangl, Anton und Wiesner, Henning
(1980):
Respiration at High Altitudes, Phosphate-Protein-Interaction: Sequence of the Hemoglobins of the Hamster (Mesocricetus aureatus) and the Camel (Camelus ferus, Camelidae)., Höhenatmung, Phosphat-Protein-Wechselwirkung: Die Sequenz der Hämoglobine des Goldhamsters (Mesocricetus aureatus) und des zweihöckerigen Kamels (Trampeltier, Camelus ferus, Camelidae).
In: Journal of the Chemical Society of Pakistan, Vol. 2, No. 1: pp. 1-7
[PDF, 775kB]
1979
This list was generated on Mon Oct 14 12:50:43 2024 CEST.