Chemistry and Pharmacy > Department of Biochemistry

2022

Stafford, Che A.; Gassauer, Alicia-Marie; Oliveira Mann, Carina C. de; Tanzer, Maria C. ORCID: 0000-0002-4657-9869; Fessler, Evelyn; Wefers, Benedikt ORCID: 0000-0002-2492-9389; Nagl, Dennis; Kuut, Gunnar; Sulek, Karolina; Vasilopoulou, Catherine; Schwojer, Sophia J. ORCID: 0000-0002-1747-4144; Wiest, Andreas ORCID: 0000-0003-2525-6304; Pfautsch, Marie K.; Wurst, Wolfgang ORCID: 0000-0003-4422-7410; Yabal, Monica ORCID: 0000-0003-3495-7671; Fröhlich, Thomas ORCID: 0000-0002-4709-3211; Mann, Matthias ORCID: 0000-0003-1292-4799; Gisch, Nicolas ORCID: 0000-0003-3260-5269; Jae, Lucas T. ORCID: 0000-0002-3531-1760; Hornung, Veit ORCID: 0000-0002-4150-194X (2022): Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation. In: Nature, Vol. 609: pp. 590-596 [PDF, 10MB]

2021

Heiss, Matthias; Borland, Kayla; Yoluç, Yasemin; Kellner, Stefanie (2021): Quantification of Modified Nucleosides in the Context of NAIL-MS. In: McMahon, Mary (ed.) : RNA Modifications. Methods in Molecular Biology, Vol. 2298. pp. 279-306

Kratzat, Hanna; Mackens‐Kiani, Timur; Ameismeier, Michael; Potocnjak, Mia; Cheng, Jingdong; Dacheux, Estelle; Namane, Abdelkader; Berninghausen, Otto; Herzog, Franz ORCID: 0000-0001-8270-1449; Fromont‐Racine, Micheline; Becker, Thomas; Beckmann, Roland (2021): A structural inventory of native ribosomal ABCE1‐43S pre‐initiation complexes. In: EMBO, Vol. 40, No. 1 [PDF, 12MB]

Tahk, Siret; Vick, Binje; Hiller, Björn; Schmitt, Saskia; Marcinek, Anetta; Perini, Enrico D.; Leutbecher, Alexandra; Augsberger, Christian; Reischer, Anna; Tast, Benjamin; Humpe, Andreas; Jeremias, Irmela; Subklewe, Marion; Fenn, Nadja C.; Hopfner, Karl-Peter ORCID: 0000-0002-4528-8357 (2021): SIRPα-αCD123 fusion antibodies targeting CD123 in conjunction with CD47 blockade enhance the clearance of AML-initiating cells. In: Journal of hematology & oncology, Vol. 14, 155 [PDF, 3MB]

2020

Ameismeier, Michael; Zemp, Ivo; Heuvel, Jasmin van den; Thoms, Matthias; Berninghausen, Otto; Kutay, Ulrike; Beckmann, Roland (2020): Structural basis for the final steps of human 40S ribosome maturation. In: Nature, Vol. 587, No. 7835: pp. 683-687

Basu, Aakash; Bobrovnikov, Dmitriy G.; Qureshi, Zan; Kayikcioglu, Tunc; Ngo, Thuy T. M.; Ranjan, Anand; Eustermann, Sebastian; Cieza, Basilio; Morgan, Michael T.; Hejna, Miroslav; Rube, H. Tomas; Hopfner, Karl-Peter; Wolberger, Cynthia; Song, Jun S.; Ha, Taekjip (2020): Measuring DNA mechanics on the genome scale. In: Nature, Vol. 589, No. 7842: pp. 462-467

Blagotinsek, Vitan; Schwan, Meike; Steinchen, Wieland; Mrusek, Devid; Hook, John C.; Rossmann, Florian; Freibert, Sven A.; Kratzat, Hanna; Murat, Guillaume; Kressler, Dieter; Beckmann, Roland; Beeby, Morgan; Thormann, Kai M.; Bange, Gert (2020): An ATP-dependent partner switch links flagellar C-ring assembly with gene expression. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 34: pp. 20826-20835

Brea, Deborah; Soler, Laura; Fleurot, Isabelle; Melo, Sandrine; Chevaleyre, Claire; Berri, Mustapha; Labas, Valerie; Teixeira-Gomes, Ana-Paula; Pujo, Julien; Cenac, Nicolas; Baehr, Andrea; Klymiuk, Nikolai; Guillon, Antoine; Si-Tahar, Mustapha; Caballero, Ignacio (2020): Intrinsic alterations in peripheral neutrophils from cystic fibrosis newborn piglets. In: Journal of Cystic Fibrosis, Vol. 19, No. 5: pp. 830-836

Buschauer, Robert; Matsuo, Yoshitaka; Sugiyama, Takato; Chen, Ying-Hsin; Alhusaini, Najwa; Sweet, Thomas; Ikeuchi, Ken; Cheng, Jingdong; Matsuki, Yasuko; Nobuta, Risa; Gilmozzi, Andrea; Berninghausen, Otto; Tesina, Petr; Becker, Thomas; Coller, Jeff; Inada, Toshifumi; Beckmann, Roland (2020): The Ccr4-Not complex monitors the translating ribosome for codon optimality. In: Science, Vol. 368, No. 6488, eaay6912

Ceolin, Stefano; Hanf, Monika; Bozek, Marta; Storti, Andrea Ennio; Gompel, Nicolas; Unnerstall, Ulrich; Jung, Christophe; Gaul, Ulrike (2020): A sensitive mNeonGreen reporter system to measure transcriptional dynamics in Drosophila development. In: Communications Biology, Vol. 3, No. 1, 663

Chakraborty, Shounak; Canzar, Stefan; Marschall, Tobias; Schulz, Marcel H. (2020): Chromatyping: Reconstructing Nucleosome Profiles from NOMe Sequencing Data. In: Journal of Computational Biology, Vol. 27, No. 3: pp. 330-341

Cheng, Jingdong; Lau, Benjamin; La Venuta, Giuseppe; Ameismeier, Michael; Berninghausen, Otto; Hurt, Ed; Beckmann, Roland (2020): 90S pre-ribosome transformation into the primordial 40S subunit. In: Science, Vol. 369, No. 6510: pp. 1470-1476

Cunha Bustamante-Filho, Ivan; Renato Menegassi, Silvio; Ribas Pereira, Gabriel; Dias Salton, Gabrielle; Mosena Munari, Fernanda; Roberto Schneider, Marlon; Costa Mattos, Rodrigo; Otavio Jardim Barcellos, Julio; Pereira Laurino, Jomar; Obino Cirne-Lima, Elizabeth; Ines Mascarenhas Jobim, Maria (2020): Bovine seminal plasma osteopontin: Structural modelling, recombinant expression and its relationship with semen quality. In: Andrologia, Vol. 53, No. 1, e13905

Do, Van Hoan; Elbassioni, Khaled; Canzar, Stefan (2020): Sphetcher: Spherical Thresholding Improves Sketching of Single-Cell Transcriptomic Heterogeneity. In: Iscience, Vol. 23, No. 6, 101126

Fessler, Evelyn; Eckl, Eva-Maria; Schmitt, Sabine; Mancilla, Igor Alves; Meyer-Bender, Matthias F.; Hanf, Monika; Philippou-Massier, Julia; Krebs, Stefan; Zischka, Hans; Jae, Lucas T. (2020): A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol. In: Nature, Vol. 579, No. 7799: pp. 433-437

Gegenfurtner, Katrin; Fröhlich, Thomas; Flenkenthaler, Florian; Koesters, Miwako; Fritz, Sebastien; Desnoes, Olivier; Le Bourhis, Daniel; Salvetti, Pascal; Sandra, Olivier; Charpigny, Gilles; Mermillod, Pascal; Lonergan, Patrick; Wolf, Eckhard; Arnold, Georg J. (2020): Genetic merit for fertility alters the bovine uterine luminal fluid proteome. In: Biology of Reproduction, Vol. 102, No. 3: pp. 730-739

Ghodgaonkar-Steger, Medini; Potocnjak, Mia; Zimniak, Tomasz; Fischböck-Halwachs, Josef; Solis-Mezarino, Victor; Singh, Sylvia; Speljko, Tea; Hagemann, Götz; Drexler, David Jan; Witte, Gregor; Herzog, Franz ORCID: 0000-0001-8270-1449 (2020): C-Terminal Motifs of the MTW1 Complex Cooperatively Stabilize Outer Kinetochore Assembly in Budding Yeast. In: Cell reports, Vol. 32, No. 13, 108190 [PDF, 5MB]

Haass, Christian ORCID: 0000-0002-4869-1627; Sewald, Bettina (19. December 2020): Weder Gans noch Rotwein schmecken. In: Münchner Merkur Ausgabe Geretsrieder Merkur, No. 294: p. 4

Helfrich, Anika L.; Reichenbach, Horst-Dieter; Meyerholz, Marie M.; Schoon, Heinz-Adolf; Arnold, Georg J.; Fröhlich, Thomas; Weber, Frank; Zerbe, Holm (2020): Novel sampling procedure to characterize bovine subclinical endometritis by uterine secretions and tissue. In: Theriogenology, Vol. 141: pp. 186-196

Hinrichs, Arne; Riedel, Evamaria O.; Klymiuk, Nikolai; Blutke, Andreas; Kemter, Elisabeth; Laengin, Matthias; Dahlhoff, Maik; Kessler, Barbara; Kurome, Mayuko; Zakhartchenko, Valeri; Jemiller, Eva-Maria; Ayares, David; Bidlingmaier, Martin; Flenkenthaler, Florian; Hrabe de Angelis, Martin; Arnold, Georg J.; Reichart, Bruno; Fröhlich, Thomas; Wolf, Eckhard (2020): Growth hormone receptor knockout to reduce the size of donor pigs for preclinical xenotransplantation studies. In: Xenotransplantation, Vol. 28, No. 2, e12664

Hoesl, Christine; Zanuttigh, Enrica; Fröhlich, Thomas; Philippou-Massier, Julia; Krebs, Stefan; Blum, Helmut; Dahlhoff, Maik (2020): The secretome of skin cancer cells activates the mTOR/MYC pathway in healthy keratinocytes and induces tumorigenic properties. In: Biochimica et Biophysica Acta-Molecular Cell Research, Vol. 1867, No. 8, 118717

Hopfner, Karl-Peter ORCID: 0000-0002-4528-8357; Hornung, Veit ORCID: 0000-0002-4150-194X (18. May 2020): Molecular mechanisms and cellular functions of cGAS-STING signalling. In: Nature Reviews Molecular Cell Biology, Vol. 21: pp. 501-521 [PDF, 13MB]

Huppertz, Christine; Jager, Benedikt; Wieczorek, Grazyna; Engelhard, Peggy; Oliver, Stephen J.; Bauernfeind, Franz-Georg; Littlewood-Evans, Amanda; Welte, Tobias; Hornung, Veit; Prasse, Antje (2020): The NLRP3 inflammasome pathway is activated in sarcoidosis and involved in granuloma formation. In: European Respiratory Journal, Vol. 55, No. 3, 1900119

Jansma, Marijke; Linke-Winnebeck, Christian; Eustermann, Sebastian; Lammens, Katja; Kostrewa, Dirk; Stakyte, Kristina; Litz, Claudia; Kessler, Brigitte; Hopfner, Karl-Peter (2020): Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State. In: Structure, Vol. 28, No. 1: pp. 83-95

Kater, Lukas; Mitterer, Valentin; Thoms, Matthias; Cheng, Jingdong; Berninghausen, Otto; Beckmann, Roland; Hurt, Ed (2020): Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis. In: Molecular Cell, Vol. 79, No. 4: pp. 615-628

Kater, Lukas; Wagener, Nikola; Berninghausen, Otto; Becker, Thomas; Neupert, Walter; Beckmann, Roland (2020): Structure of the Bcs1 AAA-ATPase suggests an airlock-like translocation mechanism for folded proteins. In: Nature Structural & Molecular Biology, Vol. 27, No. 2: pp. 142-149

Kemter, Elisabeth; Schnieke, Angelika; Fischer, Konrad; Cowan, Peter J.; Wolf, Eckhard (2020): Xeno-organ donor pigs with multiple genetic modifications - the more the better? In: Current Opinion in Genetics & Development, Vol. 64: pp. 60-65

Killinger, Kerstin; Boehm, Miriam; Steinbach, Philine; Hagemann, Goetz; Blueggel, Mike; Jaenen, Karolin; Hohoff, Simone; Bayer, Peter; Herzog, Franz; Westermann, Stefan (2020): Auto-inhibition of Mif2/CENP-C ensures centromere-dependent kinetochore assembly in budding yeast. In: EMBO Journal, Vol. 39, No. 14, e102938

Koepke, Lennart; Winter, Benjamin; Grenzner, Alexander; Regensburger, Kerstin; Engelhart, Susanne; Merwe, Johannes A. van der; Krebs, Stefan; Blum, Helmut; Kirchhoff, Frank; Sparrer, Konstantin M. J. (2020): An improved method for high-throughput quantification of autophagy in mammalian cells. In: Scientific Reports, Vol. 10, No. 1, 12241 [PDF, 6MB]

Kratzat, Hanna; Mackens-Kiani, Timur; Ameismeier, Michael; Potocnjak, Mia; Cheng, Jingdong; Dacheux, Estelle; Namane, Abdelkader; Berninghausen, Otto; Herzog, Franz; Fromont-Racine, Micheline; Becker, Thomas; Beckmann, Roland (2020): A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes. In: EMBO Journal, Vol. 40, No. 1, e105179

Lampl, Sandra; Janas, Marianne K.; Donakonda, Sainitin; Brugger, Marcus; Lohr, Kerstin; Schneider, Annika; Manske, Katrin; Sperl, Laura E.; Klaeger, Susan; Kuester, Bernhard; Wettmarshausen, Jennifer; Müller, Constanze; Laschinger, Melanie; Hartmann, Daniel; Hueser, Norber; Perocchi, Fabiana; Schmitt-Kopplin, Philippe; Hagn, Franz; Zender, Lars; Hornung, Veit; Borner, Christoph; Pichlmair, Andreas; Kashkar, Hamid; Klingenspor, Martin; Prinz, Marco; Schreiner, Sabrina; Conrad, Marcus; Jost, Philipp J.; Zischka, Hans; Steiger, Katja; Kroenke, Martin; Zehn, Dietmar; Protzer, Ulrike; Heikenwaelder, Mathias; Knolle, Percy A.; Wohlleber, Dirk (2020): Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes. In: Journal of Hepatology, Vol. 73, No. 6: pp. 1347-1359

Latoscha, Andreas; Drexler, David Jan; Al-Bassam, Mahmoud M.; Bandera, Adrian M.; Kaever, Volkhard; Findlay, Kim C.; Witte, Gregor; Tschowri, Natalia (2020): c-di-AMP hydrolysis by the phosphodiesterase AtaC promotes differentiation of multicellular bacteria. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 13: pp. 7392-7400

Lauterbach-Riviere, Lise; Bergez, Maiwenn; Moench, Saskia; Qu, Bingqian; Riess, Maximilian; Vondran, Florian W. R.; Liese, Juliane; Hornung, Veit; Urban, Stephan; König, Renate (2020): Hepatitis B Virus DNA is a Substrate for the cGAS/STING Pathway but is not Sensed in Infected Hepatocytes. In: Viruses-Basel, Vol. 12, No. 6, 592

Limbrick, Emilianne M.; Graf, Michael; Derewacz, Dagmara K.; Nguyen, Fabian; Spraggins, Jeffrey M.; Wieland, Maximiliane; Ynigez-Gutierrez, Audrey E.; Reisman, Benjamin J.; Zinshteyn, Boris; McCulloch, Kathryn M.; Iverson, T. M.; Green, Rachel; Wilson, Daniel N.; Bachmann, Brian O. (2020): Bifunctional Nitrone-Conjugated Secondary Metabolite Targeting the Ribosome. In: Journal of the American Chemical Society, Vol. 142, No. 43: pp. 18369-18377

Linder, Andreas; Bauernfried, Stefan; Cheng, Yiming; Albanese, Manuel; Jung, Christophe; Keppler, Oliver T.; Hornung, Veit (2020): CARD8 inflammasome activation triggers pyroptosis in human T cells. In: EMBO Journal, Vol. 39, No. 19, e105071

Linse, Sara; Thulin, Eva; Nilsson, Hanna; Stigler, Johannes (2020): Benefits and constrains of covalency: the role of loop length in protein stability and ligand binding. In: Scientific Reports, Vol. 10, No. 1, 20108 [PDF, 1MB]

Loregger, Anke; Raaben, Matthijs; Nieuwenhuis, Joppe; Tan, Josephine M. E.; Jae, Lucas T.; Hengel, Lisa G. van den; Hendrix, Sebastian; Berg, Marlene van den; Scheij, Saskia; Song, Ji-Ying; Huijbers, Ivo J.; Kroese, Lona J.; Ottenhoff, Roelof; Weeghel, Michel van; Sluis, Bart van de; Brummelkamp, Thijn; Zelcer, Noam (2020): Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism. In: Nature Communications, Vol. 11, No. 1, 1128 [PDF, 3MB]

Lucienne, Marie; Aguilar-Pimentel, Juan Antonio; Amarie, Oana V.; Becker, Lore; Calzada-Wack, Julia; da Silva-Buttkus, Patricia; Garrett, Lillian; Holter, Sabine M.; Mayer-Kuckuk, Philipp; Rathkolb, Birgit; Rozman, Jan; Spielmann, Nadine; Treise, Irina; Busch, Dirk H.; Klopstock, Thomas; Schmidt-Weber, Carsten; Wolf, Eckhard; Wurst, Wolfgang; Forny, Merima; Mathis, Deborah; Fingerhut, Ralph; Froese, D. Sean; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin; Baumgartner, Matthias R. (2020): In-depth phenotyping reveals common and novel disease symptoms in a hemizygous knock-in mouse model (Mut-ko/ki) of mut-type methylmalonic aciduria. In: Biochimica et Biophysica Acta-Molecular Basis of Disease, Vol. 1866, No. 3, 165622

Ludwig, Barbara; Wolf, Eckhard (2020): Transplantation und künstliches Pankreas. In: Diabetologe, Vol. 16, No. 7: pp. 662-668

Margos, Gabriele; Fedorova, Natalia; Becker, Noemie S.; Kleinjan, Joyce E.; Marosevic, Durdica; Krebs, Stefan; Hui, Lucia; Fingerle, Volker; Lane, Robert S. (2020): Borrelia maritima sp. nov., a novel species of the Borrelia burgdorferi sensu tato complex, occupying a basal position to North American species. In: International Journal of Systematic and Evolutionary Microbiology, Vol. 70, No. 2: pp. 849-856

Matsuo, Yoshitaka; Tesina, Petr; Nakajima, Shizuka; Mizuno, Masato; Endo, Akinori; Buschauer, Robert; Cheng, Jingdong; Shounai, Okuto; Ikeuchi, Ken; Saeki, Yasushi; Becker, Thomas; Beckmann, Roland; Inada, Toshifumi (2020): RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1. In: Nature Structural & Molecular Biology, Vol. 27, No. 4: pp. 323-332

Mehlich, Alexander; Fang, Jie; Pelz, Benjamin; Li, Hongbin; Stigler, Johannes (7. December 2020): Slow Transition Path Times Reveal a Complex Folding Barrier in a Designed Protein. In: Frontiers in Chemistry, Vol. 8, 587824: pp. 1-11 [PDF, 1MB]

Messner, Martina; Schmitt, Sabine; Ardelt, Maximilian A.; Fröhlich, Thomas; Müller, Martin; Pein, Helmut; Huber-Cantonati, Petra; Ortler, Carina; König, Lars M.; Zobel, Lena; Koeberle, Andreas; Arnold, Georg J.; Rothenfusser, Simon; Kiemer, Alexandra K.; Gerbes, Alexander L.; Zischka, Hans; Vollmar, Angelika M.; Pachmayr, Johanna (2020): Metabolic implication of tigecycline as an efficacious second-line treatment for sorafenib-resistant hepatocellular carcinoma. In: FASEB Journal, Vol. 34, No. 9: pp. 11860-11882

Michalski, Sebastian; de Oliveira Mann, Carina C.; Stafford, Che A.; Witte, Gregor; Bartho, Joseph; Lammens, Katja; Hornung, Veit; Hopfner, Karl-Peter (2020): Structural basis for sequestration and autoinhibition of cGAS by chromatin. In: Nature, Vol. 587, No. 7835: pp. 678-682

Mukherjee, Somnath; Erramilli, Satchal K.; Ammirati, Mark; Alvarez, Frances J. D.; Fennell, Kimberly F.; Purdy, Michael D.; Skrobek, Blazej M.; Radziwon, Katarzyna; Coukos, John; Kang, Yanyong; Dutka, Przemyslaw; Gao, Xiang; Qiu, Xiayang; Yeager, Mark; Xu, H. Eric; Han, Seungil; Kossiakoff, Anthony A. (2020): Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins. In: Nature Communications, Vol. 11, No. 1, 1598 [PDF, 4MB]

Nitschko, Volker; Kunzelmann, Stefan; Fröhlich, Thomas; Arnold, Georg J.; Förstemann, Klaus (2020): Trafficking of siRNA precursors by the dsRBD protein Blanks in Drosophila. In: Nucleic Acids Research, Vol. 48, No. 7: pp. 3906-3921

Nuerenberg-Goloub, Elina; Kratzat, Hanna; Heinemann, Holger; Heuer, Andre; Koetter, Peter; Berninghausen, Otto; Becker, Thomas; Tampe, Robert; Beckmann, Roland (2020): Molecular analysis of the ribosome recycling factor ABCE1 bound to the 30S post-splitting complex. In: EMBO Journal, Vol. 39, No. 9, e103788

Osterman, Ilya A.; Wieland, Maximiliane; Maviza, Tinashe P.; Lashkevich, Kseniya A.; Lukianov, Dmitrii A.; Komarova, Ekaterina S.; Zakalyukina, Yuliya V.; Buschauer, Robert; Shiriaev, Dmitrii I.; Leyn, Semen A.; Zlamal, Jaime E.; Biryukov, Mikhail V.; Skvortsov, Dmitry A.; Tashlitsky, Vadim N.; Polshakov, Vladimir I.; Cheng, Jingdong; Polikanov, Yury S.; Bogdanov, Alexey A.; Osterman, Andrei L.; Dmitriev, Sergey E.; Beckmann, Roland; Dontsova, Olga A.; Wilson, Daniel N.; Sergiev, Petr V. (2020): Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel. In: Nature Chemical Biology, Vol. 16, No. 10: pp. 1071-1077

Pfaff, Florian; Neubauer-Juric, Antonie; Krebs, Stefan; Hauser, Andreas; Singer, Stefanie; Blum, Helmut; Hoffmann, Bernd (2020): Full genome sequence of bovine alphaherpesvirus 2 (BoHV-2). In: Archives of Virology, Vol. 166, No. 2: pp. 639-643

Pinci, Francesca; Gaidt, Moritz M.; Jung, Christophe; Kuut, Gunnar; Jackson, Margaret A.; Bauernfried, Stefan; Hornung, Veit (2020): C-tag TNF: a reporter system to study TNF shedding. In: Journal of Biological Chemistry, Vol. 295, No. 52: pp. 18065-18075

Ponserre, Marion; Peters, Christian; Fermani, Federica; Conzelmann, Karl-Klaus; Klein, Rüdiger (2020): The Insula Cortex Contacts Distinct Output Streams of the Central Amygdala. In: Journal of Neuroscience, Vol. 40, No. 46: pp. 8870-8882

Reinking, Hannah K.; Hofmann, Kay; Stingele, Julian (2020): Function and evolution of the DNA-protein crosslink proteases Wss1 and SPRTN. In: DNA Repair, Vol. 88, 102822

Reinking, Hannah K.; Kang, Hyun-Seo; Götz, Maximilian J.; Li, Hao-Yi; Kieser, Anja; Zhao, Shubo; Acampora, Aleida C.; Weickert, Pedro; Fessler, Evelyn; Jae, Lucas T.; Sattler, Michael; Stingele, Julian (2020): DNA Structure-Specific Cleavage of DNA-Protein Crosslinks by the SPRTN Protease. In: Molecular Cell, Vol. 80, No. 1: pp. 102-113

Renner, Simone; Blutke, Andreas; Clauss, Sebastian; Deeg, Cornelia A.; Kemter, Elisabeth; Merkus, Daphne; Wanke, Rüdiger; Wolf, Eckhard (2020): Porcine models for studying complications and organ crosstalk in diabetes mellitus. In: Cell and Tissue Research, Vol. 380, No. 2: pp. 341-378

Riedel, Evamaria O.; Hinrichs, Arne; Kemter, Elisabeth; Dahlhoff, Maik; Backman, Mattias; Rathkolb, Birgit; Prehn, Cornelia; Adamski, Jerzy; Renner, Simone; Blutke, Andreas; Hrabe de Angelis, Martin; Bidlingmaier, Martin; Schopohl, Jochen; Arnold, Georg J.; Fröhlich, Thomas; Wolf, Eckhard (2020): Functional changes of the liver in the absence of growth hormone (GH) action - Proteomic and metabolomic insights from a GH receptor deficient pig model. In: Molecular Metabolism, Vol. 36, 100978

Schmid, Nina; Missel, Annika; Petkov, Stoyan; Stöckl, Jan B.; Flenkenthaler, Florian; Arnold, Georg J.; Fröhlich, Thomas; Behr, Rüdiger; Mayerhofer, Artur (2020): A translational cellular model for the study of peritubular cells of the testis. In: Reproduction, Vol. 160, No. 2: pp. 259-268

Schmitt, Saskia; Tahk, Siret; Lohner, Alina; Haenel, Gerulf; Maiser, Andreas; Hauke, Martina; Patel, Lubna; Rothe, Maurine; Josenhans, Christine; Leonhardt, Heinrich; Griffioen, Marieke; Deiser, Katrin; Fenn, Nadja C.; Hopfner, Karl-Peter; Subklewe, Marion (12. November 2020): Fusion of Bacterial Flagellin to a Dendritic Cell-Targeting αCD40 Antibody Construct Coupled With Viral or Leukemia-Specific Antigens Enhances Dendritic Cell Maturation and Activates Peptide-Responsive T Cells. In: Frontiers in Immunology, Vol. 11, 602802: pp. 1-16 [PDF, 3MB]

Schnatbaum, Karsten; Solis-Mezarino, Victor; Pokrovsky, Daniil; Schaefer, Frederike; Nagl, Dennis; Hornberger, Lars; Zerweck, Johannes; Knaute, Tobias; Avramova-Nehmer, Julia; Schutkowski, Mike; Hornung, Veit; Wenschuh, Holger; Voelker-Albert, Moritz Carl; Imhof, Axel; Reimer, Ulf (2020): New Approaches for Absolute Quantification of Stable-Isotope-Labeled Peptide Standards for Targeted Proteomics Based on a UV Active Tag. In: Proteomics, Vol. 20, No. 10, 2000007

Schnepf, Max; Ludwig, Claudia; Bandilla, Peter; Ceolin, Stefano; Unnerstall, Ulrich; Jung, Christophe; Gaul, Ulrike (2020): Sensitive Automated Measurement of Histone-DNA Affinities in Nucleosomes. In: Iscience, Vol. 23, No. 2, 100824

Sinha, Niladri K.; Ordureau, Alban; Best, Katharina; Saba, James A.; Zinshteyn, Boris; Sundaramoorthy, Elayanambi; Fulzele, Amit; Garshott, Danielle M.; Denk, Timo; Thoms, Matthias; Paulo, Joao A.; Harper, J. Wade; Bennett, Eric J.; Beckmann, Roland; Green, Rachel (2020): EDF1 coordinates cellular responses to ribosome collisions. In: eLife, Vol. 9, e58828 [PDF, 8MB]

Stöckl, Jan B.; Schmid, Nina; Flenkenthaler, Florian; Drummer, Charis; Behr, Rüdiger; Mayerhofer, Artur; Arnold, Georg J.; Fröhlich, Thomas (2020): Proteomic Insights into Senescence of Testicular Peritubular Cells from a Nonhuman Primate Model. In: Cells, Vol. 9, No. 11, 2498

Tanzer, Maria C.; Frauenstein, Annika; Stafford, Che A.; Phulphagar, Kshiti; Mann, Matthias; Meissner, Felix (2020): Quantitative and Dynamic Catalogs of Proteins Released during Apoptotic and Necroptotic Cell Death. In: Cell Reports, Vol. 30, No. 4: pp. 1260-1270

Thoms, Matthias; Buschauer, Robert; Ameismeier, Michael; Koepke, Lennart; Denk, Timo; Hirschenberger, Maximilian; Kratzat, Hanna; Hayn, Manuel; Mackens-Kiani, Timur; Cheng, Jingdong; Straub, Jan H.; Stürzel, Christina M.; Fröhlich, Thomas; Berninghausen, Otto; Becker, Thomas; Kirchhoff, Frank; Sparrer, Konstantin M. J.; Beckmann, Roland (2020): Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. In: Science, Vol. 369, No. 6508: pp. 1249-1255

Trambauer, Johannes; Rodríguez Sarmiento, Rosa María; Fukumori, Akio; Feederle, Regina; Baumann, Karlheinz; Steiner, Harald (2020): Aβ43‐producing PS1 FAD mutants cause altered substrate interactions and respond to γ‐secretase modulation. In: Embo Reports, Vol. 21, No. 1, e47996 [PDF, 1MB]

Vogel, Sven K.; Woelfer, Christian; Ramirez-Diaz, Diego A.; Flassig, Robert J.; Sundmacher, Kai; Schwille, Petra (2020): Symmetry Breaking and Emergence of Directional Flows in Minimal Actomyosin Cortices. In: Cells, Vol. 9, No. 6, 1432

Watanabe, Reika; Buschauer, Robert; Böhning, Jan; Audagnotto, Martina; Lasker, Keren; Lu, Tsan-Wen; Boassa, Daniela; Taylor, Susan; Villa, Elizabeth (2020): The In Situ Structure of Parkinson's Disease-Linked LRRK2. In: Cell, Vol. 182, No. 6: pp. 1508-1518

Weichmann, Franziska; Hett, Robert; Schepers, Aloys; Ito-Kureha, Taku; Flatley, Andrew; Slama, Kaouthar; Hastert, Florian D.; Angstman, Nicholas B.; Cardoso, M. Cristina; König, Julian; Huettelmaier, Stefan; Dieterich, Christoph; Canzar, Stefan; Helm, Mark; Heissmeyer, Vigo; Feederle, Regina; Meister, Gunter (2020): Validation strategies for antibodies targeting modified ribonucleotides. In: Rna, Vol. 26, No. 10: pp. 1489-1506

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Lichtenegger, Felix S.; Rothe, Maurine; Schnorfeil, Frauke M.; Deiser, Katrin; Krupka, Christina; Augsberger, Christian; Schlueter, Miriam; Neitz, Julia; Subklewe, Marion (2018): Targeting LAG-3 and PD-1 to Enhance T Cell Activation by Antigen-Presenting Cells. In: Frontiers in Immunology, Vol. 9, 385 [PDF, 1MB]

Linnekamp, Janneke F.; Hooff, Sander R. van; Prasetyanti, Pramudita R.; Kandimalla, Raju; Buikhuisen, Joyce Y.; Fessler, Evelyn; Ramesh, Prashanthi; Lee, Kelly A. S. T.; Bochove, Grehor G. W.; Jong, Johan H. de; Cameron, Kate; Leersum, Ronald van; Rodermond, Hans M.; Franitza, Marek; Nuernberg, Peter; Mangiapane, Laura R.; Wang, Xin; Clevers, Hans; Vermeulen, Louis; Stassi, Giorgio; Medema, Jan Paul (2018): Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models. In: Cell Death and Differentiation, Vol. 25, No. 3: pp. 616-633

Magg, Thomas; Wiebking, Volker; Conca, Raffaele; Krebs, Stefan; Arens, Stefan; Schmid, Irene; Klein, Christoph; Albert, Michael H.; Hauck, Fabian (2018): IPEX due to an exon 7 skipping FOXP3 mutation with autoimmune diabetes mellitus cured by selective T-Reg cell engraftment. In: Clinical Immunology, Vol. 191: pp. 52-58

Matsunari, Hitomi; Watanabe, Masahito; Nakano, Kazuaki; Enosawa, Shin; Umeyama, Kazuhiro; Uchikura, Ayuko; Yashima, Sayaka; Fukuda, Toru; Klymiuk, Nikolai; Kurome, Mayuko; Kessler, Barbara; Wünschd, Annegret; Zakhartchenko, Valeri; Wolf, Eckhard; Hanazono, Yutaka; Nagaya, Masaki; Umezawa, Akihiro; Nakauchi, Hiromitsu; Nagashima, Hiroshi (2018): Modeling lethal X-linked genetic disorders in pigs with ensured fertility. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 4: pp. 708-713

Mayer-Wagner, Susanne; Hammerschmid, Florian; Blum, Helmut; Krebs, Stefan; Redeker, Julia I.; Holzapfel, Boris M.; Jansson, Volkmar; Müller, Peter E. (2018): Effects of single and combined low frequency electromagnetic fields and simulated microgravity on gene expression of human mesenchymal stem cells during chondrogenesis. In: Archives of Medical Science, Vol. 14, No. 3: pp. 608-616 [PDF, 207kB]

Pertici, Irene; Bongini, Lorenzo; Melli, Luca; Bianchi, Giulio; Salvi, Luca; Falorsi, Giulia; Squarci, Caterina; Bozo, Tamas; Cojoc, Dan; Kellermayer, Miklos S. Z.; Lombardi, Vincenzo; Bianco, Pasquale (2018): A myosin II nanomachine mimicking the striated muscle. In: Nature Communications, Vol. 9, 3532 [PDF, 1MB]

Renner, Simone; Blutke, Andreas; Dobenecker, Britta; Dhom, Georg; Müller, Timo D.; Finan, Brian; Clemmensen, Christoffer; Bernau, Maren; Novak, Istvan; Rathkolb, Birgit; Senf, Steffanie; Zoels, Susanne; Roth, Mirjam; Götz, Anna; Hofmann, Susanna M.; Hrabe de Angelis, Martin; Wanke, Rüdiger; Kienzle, Ellen; Scholz, Armin M.; DiMarchi, Richard; Ritzmann, Mathias; Tschoep, Matthias H.; Wolf, Eckhard (2018): Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Gottingen minipigs. In: Molecular Metabolism, Vol. 16: pp. 180-190 [PDF, 2MB]

Rothammer, Sophie; Kunz, Elisabeth; Krebs, Stefan; Bitzer, Fanny; Hauser, Andreas; Zinovieva, Natalia; Klymiuk, Nikolai; Medugorac, Ivica (2018): Remapping of the belted phenotype in cattle on BTA3 identifies a multiplication event as the candidate causal mutation. In: Genetics Selection Evolution 50:36 [PDF, 2MB]

Rozman, Jan; Rathkolb, Birgit; Oestereicher, Manuela A.; Schütt, Christine; Ravindranath, Aakash Chavan; Leuchtenberger, Stefanie; Sharma, Sapna; Kistler, Martin; Willershaeuser, Monja; Brommage, Robert; Meehan, Terrence F.; Mason, Jeremy; Haselimashhadi, Hamed; Hough, Tertius; Mallon, Ann-Marie; Wells, Sara; Santos, Luis; Lelliott, Christopher J.; White, Jacqueline K.; Sorg, Tania; Champy, Marie-France; Bower, Lynette R.; Reynolds, Corey L.; Flenniken, Ann M.; Murray, Stephen A.; Nutter, Lauryl M. J.; Svenson, Karen L.; West, David; Tocchini-Valentini, Glauco P.; Beaudet, Arthur L.; Bosch, Fatima; Braun, Robert B.; Dobbie, Michael S.; Gao, Xiang; Herault, Yann; Moshiri, Ala; Moore, Bret A.; Lloyd, K. C. Kent; McKerlie, Colin; Masuya, Hiroshi; Tanaka, Nobuhiko; Flicek, Paul; Parkinson, Helen E.; Sedlacek, Radislav; Seong, Je Kyung; Wang, Chi-Kuang Leo; Moore, Mark; Brown, Steve D.; Tschoep, Matthias H.; Wurst, Wolfgang; Klingenspor, Martin; Wolf, Eckhard; Beckers, Johannes; Machicao, Fausto; Peter, Andreas; Staiger, Harald; Häring, Hans-Ulrich; Grallert, Harald; Campillos, Monica; Maier, Holger; Fuchs, Helmut; Gailus-Durner, Valerie; Werner, Thomas; Hrabe de Angelis, Martin (2018): Identification of genetic elements in metabolism by high-throughput mouse phenotyping. In: Nature Communications, Vol. 9, 288 [PDF, 2MB]

Ryan, D. P.; Henzel, K. S.; Pearson, B. L.; Siwek, M. E.; Papazoglou, A.; Guo, L.; Paesler, K.; Yu, M.; Müller, R.; Xie, K.; Schröder, S.; Becker, L.; Garrett, L.; Hölter, S. M.; Neff, F.; Racz, I.; Rathkolb, B.; Rozman, J.; Ehninger, G.; Klingenspor, M.; Klopstock, T.; Wolf, E.; Wurst, W.; Zimmer, A.; Fuchs, H.; Gailus-Durner, V.; Hrabe de Angelis, Martin; Sidiropoulou, K.; Weiergräber, M.; Zhou, Y.; Ehninger, D. (2018): A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice. In: Molecular Psychiatry, Vol. 23, No. 5: pp. 1345-1355

Saathoff, Jan-Hinnerk; Käshammer, Lisa; Lammens, Katja; Byrne, Robert Thomas; Hopfner, Karl-Peter (2018): The bacterial Mre11-Rad50 homolog SbcCD cleaves opposing strands of DNA by two chemically distinct nuclease reactions. In: Nucleic Acids Research, Vol. 46, No. 21: pp. 11303-11314 [PDF, 3MB]

Salomone-Stagni, Marco; Bartho, Joseph D.; Kalita, Eeshan; Rejzek, Martin; Field, Robert A.; Bellini, Dom; Walsh, Martin A.; Benini, Stefano (2018): Structural and functional analysis of Erwinia amylovora SrlD. The first crystal structure of a sorbitol-6-phosphate 2-dehydrogenase. In: Journal of Structural Biology, Vol. 203, No. 2: pp. 109-119

Salomone-Stagni, Marco; Bartho, Joseph D.; Polsinelli, Ivan; Bellini, Dom; Walsh, Martin A.; Demitri, Nicola; Benini, Stefano (2018): A complete structural characterization of the desferrioxamine E biosynthetic pathway from the fire blight pathogen Erwinia amylovora. In: Journal of Structural Biology, Vol. 202, No. 3: pp. 236-249

Schlauderer, Florian; Seeholzer, Thomas; Desfosses, Ambroise; Gehring, Torben; Strauss, Mike; Hopfner, Karl-Peter; Gutsche, Irina; Krappmann, Daniel; Lammens, Katja (2018): Molecular architecture and regulation of BCL10-MALT1 filaments. In: Nature Communications, Vol. 9, 4041 [PDF, 3MB]

Schmidt, Eva Marina; Lamprecht, Sebastian; Blaj, Cristina; Schaaf, Christian; Krebs, Stefan; Blum, Helmut; Hermeking, Heiko; Jung, Andreas; Kirchner, Thomas; Horst, David (2018): Targeting tumor cell plasticity by combined inhibition of NOT CH and MAPK signaling in colon cancer. In: Journal of Experimental Medicine, Vol. 215, No. 6: pp. 1693-1708

Schwarz, Marianne; Schall, Kevin; Kallis, Eleni; Eustermann, Sebastian; Guariento, Mara; Moldt, Manuela; Hopfner, Karl-Peter; Michaelis, Jens (2018): Single-molecule nucleosome remodeling by INO80 and effects of histone tails. In: Febs Letters, Vol. 592, No. 3: pp. 318-331

Seeholzer, Thomas; Kurz, Susanne; Schlauderer, Florian; Woods, Simone; Gehring, Torben; Widmann, Simon; Lammens, Katja; Krappmann, Daniel (2018): BCL10-CARD11 Fusion Mimics an Active CARD11 Seed That Triggers Constitutive BCL10 Oligomerization and Lymphocyte Activation. In: Frontiers in Immunology, Vol. 9, 2695 [PDF, 3MB]

Sharma, Subhalakshmi; Cermakova, Katerina; Rijck, Jan de; Demeulemeester, Jonas; Fabry, Milan; El Ashkar, Sara; Belle, Siska van; Lepsik, Martin; Tesina, Petr; Duchoslav, Vojtech; Novak, Petr; Hubalek, Martin; Srb, Pavel; Christ, Frauke; Rezacova, Pavlina; Hodges, H. Courtney; Debyser, Zeger; Veverka, Vaclav (2018): Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 30, E7053-E7062

Simmet, Kilian; Zakhartchenko, Valeri; Philippou-Massier, Julia; Blum, Helmut; Klymiuk, Nikolai; Wolf, Eckhard (2018): OCT4/POU5F1 is required for NANOG expression in bovine blastocysts. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 11: pp. 2770-2775

Simmet, Kilian; Zakhartchenko, Valeri; Wolf, Eckhard (2018): Comparative aspects of early lineage specification events in mammalian embryos - insights from reverse genetics studies. In: Cell Cycle, Vol. 17, No. 14: pp. 1688-1695

Spletter, Maria L.; Barz, Christiane; Yeroslaviz, Assa; Zhang, Xu; Lemke, Sandra B.; Bonnard, Adrien; Brunner, Erich; Cardone, Giovanni; Basler, Konrad; Habermann, Bianca H.; Schnorrer, Frank (2018): A transcriptomics resource reveals a transcriptional transition during ordered sarcomere morphogenesis in flight muscle. In: eLife, Vol. 7, e34058 [PDF, 14MB]

Stoiber, Katharina; Naglo, Olga; Pernpeintner, Carla; Zhang, Siwei; Köberle, Andreas; Ulrich, Melanie; Werz, Oliver; Müller, Rolf; Zahler, Stefan; Lohmüller, Theobald; Feldmann, Jochen; Braig, Simone (2018): Targeting de novo lipogenesis as a novel approach in anti-cancer therapy. In: British Journal of Cancer, Vol. 118, No. 1: pp. 43-51

Surup, Frank; Chauhan, Dhruv; Niggemann, Jutta; Bartok, Eva; Herrmann, Jennifer; Keck, Matthias; Zander, Wiebke; Stadler, Marc; Hornung, Veit; Müller, Rolf (2018): Activation of the NLRP3 Inflammasome by Hyaboron, a New Asymmetric Boron-Containing Macrodiolide from the Myxobacterium Hyalangium minutum. In: ACS Chemical Biology, Vol. 13, No. 10: pp. 2981-2988

Thoms, Matthias; Mitterer, Valentin; Kater, Lukas; Falquet, Laurent; Beckmann, Roland; Kressler, Dieter; Hurt, Ed (2018): Suppressor mutations in Rpf2-Rrs1 or Rpl5 bypass the Cgr1 function for pre-ribosomal 5S RNP-rotation. In: Nature Communications, Vol. 9, 4094 [PDF, 6MB]

Tian, Pengfei; Steward, Annette; Kudva, Renuka; Su, Ting; Shilling, Patrick J.; Nickson, Adrian A.; Hollins, Jeffrey J.; Beckmann, Roland; Heijne, Gunnar von; Clarke, Jane; Best, Robert B. (2018): Folding pathway of an Ig domain is conserved on and off the ribosome. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 48, E11284-E11293

Treise, Irina; Huber, Eva M.; Klein-Rodewald, Tanja; Heinemeyer, Wolfgang; Grassmann, Simon A.; Basler, Michael; Adler, Thure; Rathkolb, Birgit; Helming, Laura; Andres, Christian; Klaften, Matthias; Landbrecht, Christina; Wieland, Thomas; Strom, Tim M.; McCoy, Kathy D.; Macpherson, Andrew J.; Wolf, Eckhard; Gröttrup, Marcus; Ollert, Markus; Neff, Frauke; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin; Groll, Michael; Busch, Dirk H. (2018): Defective immuno- and thymoproteasome assembly causes severe immunodeficiency. In: Scientific Reports, Vol. 8, 5975 [PDF, 5MB]

Ugolini, Ilaria; Halic, Mario (2018): Fidelity in RNA-based recognition of transposable elements. In: Philosophical Transactions of the Royal Society B-Biological Sciences, Vol. 373, No. 1762, 20180168

Verkhratsky, Alexei; Trebak, Mohamed; Perocchi, Fabiana; Khananshvili, Daniel; Sekler, Israel (2018): Crosslink between calcium and sodium signalling. In: Experimental Physiology, Vol. 103, No. 2: pp. 157-169

Vogel, Heike; Kamitz, Anne; Hallahan, Nicole; Lebek, Sandra; Schallschmidt, Tanja; Jonas, Wenke; Jaehnert, Markus; Gottmann, Pascal; Zellner, Lisa; Kanzleiter, Timo; Damen, Mareike; Altenhofen, Delsi; Burkhardt, Ralph; Renner, Simone; Dahlhoff, Maik; Wolf, Eckhard; Müller, Timo D.; Blueher, Matthias; Joost, Hans-Georg; Chadt, Alexandra; Al-Hasani, Hadi; Schürmann, Annette (2018): A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and Type 2 diabetes. In: Human Molecular Genetics, Vol. 27, No. 17: pp. 3099-3112

Westbye, Alexander B.; Kater, Lukas; Wiesmann, Christina; Ding, Hao; Yip, Calvin K.; Beatty, J. Thomas (2018): The Protease ClpXP and the PAS Domain Protein DivL Regulate CtrA and Gene Transfer Agent Production in Rhodobacter capsulatus. In: Applied and Environmental Microbiology, Vol. 84, No. 11

Xie, Kan; Ryan, Devon P.; Pearson, Brandon L.; Henzel, Kristin S.; Neff, Frauke; Vidal, Ramon O.; Hennion, Magali; Lehmann, Isabelle; Schleif, Melvin; Schröder, Susanne; Adler, Thure; Rathkolb, Birgit; Rozman, Jan; Schütz, Anna-Lena; Prehn, Cornelia; Mickael, Michel E.; Weiergraber, Marco; Adamski, Jerzy; Busch, Dirk H.; Ehninger, Gerhard; Matynia, Anna; Jackson, Walker S.; Wolf, Eckhard; Fuchs, Helmut; Gailus-Durner, Valerie; Bonn, Stefan; Hrabe de Angelis, Martin; Ehninger, Dan (2018): Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 10, E2348-E2357 [PDF, 2MB]

Yepez, Vicente A.; Kremer, Laura S.; Iuso, Arcangela; Gusic, Mirjana; Kopajtich, Robert; Konarikova, Eliska; Nadel, Agnieszka; Wachutka, Leonhard; Prokisch, Holger; Gagneur, Julien (2018): OCR-Stats: Robust estimation and statistical testing of mitochondrial respiration activities using Seahorse XF Analyzer.
In: PLOS One 13(7), e0199938 [PDF, 3MB]

2017

Ahdash, Zainab; Byrne, Robert; Hopfner, Karl-Peter; Politis, Argyris (2017): Dissecting the Mechanism of the HerA NurA DNA Break Resection Complex using Native Mass Spectrometry. In: Biophysical Journal, Vol. 112, No. 3: 515A-515A

Albisetti, Gioele W.; Ghanem, Alexander; Foster, Edmund; Conzelmann, Karl-Klaus; Zeilhofer, Hanns Ulrich; Wildner, Hendrik (2017): Identification of Two Classes of Somatosensory Neurons That Display Resistance to Retrograde Infection by Rabies Virus. In: Journal of Neuroscience, Vol. 37, No. 43: pp. 10358-10371

Andreeva, Liudmila; Hiller, Björn; Kostrewa, Dirk; Lässig, Charlotte; Oliveira Mann, Carina C. de; Drexler, David Jan; Maiser, Andreas; Gaidt, Moritz; Leonhardt, Heinrich; Hornung, Veit; Hopfner, Karl-Peter (2017): cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders. In: Nature, Vol. 549, No. 7672: pp. 394-398

Antonopoulos, Alexios; Psarros, Konstantinos; Abdesselem, Mouna; Szolc, Piotr; Baeuerle, Patrick (2017): Dr Patrick Baeuerle, MPMCapital, talks with young scientists. In: Cardiovascular Research, Vol. 113, No. 12, E42-E42

Arduino, Daniela M.; Wettmarshausen, Jennifer; Vais, Horia; Navas-Navarro, Paloma; Cheng, Yiming; Leimpek, Anja; Ma, Zhongming; Delrio-Lorenzo, Alba; Giordano, Andrea; Garcia-Perez, Cecilia; Medard, Guillaume; Kuster, Bernhard; Garcia-Sancho, Javier; Mokranjac, Dejana; Foskett, J. Kevin; Teresa Alonso, M.; Perocchi, Fabiana (2017): Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening. In: Molecular Cell, Vol. 67, No. 4: pp. 711-723

Ayoubian, Hiresh; Fröhlich, Thomas; Pogodski, Dagmar; Flatley, Andrew; Kremmer, Elisabeth; Schepers, Aloys; Feederle, Regina; Arnold, Georg J.; Grässer, Friedrich A. (2017): Antibodies against the mono-methylated arginine-glycine repeat (MMA-RG) of the Epstein-Barr virus nuclear antigen 2 (EBNA2) identify potential cellular proteins targeted in viral transformation. In: Journal of General Virology, Vol. 98, No. 8: pp. 2128-2142

Baejen, Carlo; Andreani, Jessica; Torkler, Phillipp; Battaglia, Sofia; Schwalb, Bjoern; Lidschreiber, Michael; Maier, Kerstin C.; Boltendahl, Andrea; Rus, Petra; Esslinger, Stephanie; Söding, Johannes; Cramer, Patrick (2017): Genome-wide Analysis of RNA Polymerase II Termination at Protein-Coding Genes. In: Molecular Cell, Vol. 66, No. 1: pp. 38-49

Batelli, Sara; Kremer, Malte; Jung, Christophe; Gaul, Ulrike (2017): Application of MultiColor FlpOut Technique to Study High Resolution Single Cell Morphologies and Cell Interactions of Glia in Drosophila. In: Jove-Journal of Visualized Experiments, No. 128, e56177

Bauersachs, Stefan; Simintiras, Constantine A.; Sturmey, Roger G.; Krebs, Stefan; Bick, Jochen; Blum, Helmut; Wolf, Eckhard; Lonergan, Pat; Forde, Niamh (2017): Effect of metabolic status on conceptus-maternal interactions on day 19 in dairy cattle: II. Effects on the endometrial transcriptome. In: Biology of Reproduction, Vol. 97, No. 3: pp. 413-425

Baum, Rebecca; Sharma, Shruti; Organ, Jason M.; Jakobs, Christopher; Hornung, Veit; Burr, David B.; Marshak-Rothstein, Ann; Fitzgerald, Katherine A.; Gravallese, Ellen M. (2017): STING Contributes to Abnormal Bone Formation Induced by Deficiency of DNase II in Mice. In: Arthritis & Rheumatology, Vol. 69, No. 2: pp. 460-471

Beckert, Bertrand; Abdelshahid, Maha; Schäfer, Heinrich; Steinchen, Wieland; Arenz, Stefan; Berninghausen, Otto; Beckmann, Roland; Bange, Gert; Turgay, Kürsad; Wilson, Daniel N. (2017): Structure of the Bacillus subtilis hibernating 100S ribosome reveals the basis for 70S dimerization. In: Embo Journal, Vol. 36, No. 14: pp. 2061-2072

Bhat, Javaid Y.; Milicic, Goran; Thieulin-Pardo, Gabriel; Bracher, Andreas; Maxwell, Andrew; Ciniawsky, Susanne; Müller-Cajar, Oliver; Engen, John R.; Hartl, F. Ulrich; Wendler, Petra; Hayer-Hartl, Manajit (2017): Mechanism of Enzyme Repair by the AAA(+) Chaperone Rubisco Activase. In: Molecular Cell, Vol. 67, No. 5: pp. 744-756

Blaj, Cristina; Bringmann, Agnes; Schmidt, Eva Marina; Urbischek, Manuela; Lamprecht, Sebastian; Fröhlich, Thomas; Arnold, Georg J.; Krebs, Stefan; Blum, Helmut; Hermeking, Heiko; Jung, Andreas; Kirchner, Thomas; Horst, David (2017): ADNP Is a Therapeutically Inducible Repressor of WNT Signaling in Colorectal Cancer. In: Clinical Cancer Research, Vol. 23, No. 11: pp. 2769-2780

Blutke, Andreas; Renner, Simone; Flenkenthaler, Florian; Backman, Mattias; Häsner, Serena; Kemter, Elisabeth; Ländström, Erik; Braun-Reichhart, Christina; Albl, Barbara; Streckel, Elisabeth; Rathkolb, Birgit; Prehn, Cornelia; Palladini, Alessandra; Grzybek, Michal; Krebs, Stefan; Bauersachs, Stefan; Bähr, Andrea; Brühschwein, Andreas ORCID: 0000-0002-7833-8031; Deeg, Cornelia A.; Monte, Erica de; Dmochewitz, Michaela; Eberle, Caroline; Emrich, Daniela; Fux, Robert; Groth, Frauke; Gumbert, Sophie; Heitmann, Antonia; Hinrichs, Arne; Kessler, Barbara; Kurome, Mayuko; Leipig-Rudolph, Miriam; Matiasek, Kaspar; Öztürk, Hazal; Otzdorff, Christiane; Reichenbach, Myriam; Reichenbach, Horst Dieter; Rieger, Alexandra; Rieseberg, Birte; Rosati, Marco; Saucedo, Manuel Nicolas; Schleicher, Anna; Schneider, Marlon R.; Simmet, Kilian; Steinmetz, Judith; Übel, Nicole; Zehetmaier, Patrizia; Jung, Andreas; Adamski, Jerzy; Coskun, Ünal; Hrabe de Angelis, Martin; Simmet, Christian; Ritzmann, Mathias; Meyer-Lindenberg, Andrea; Blum, Helmut; Arnold, Georg J.; Fröhlich, Thomas; Wanke, Rüdiger; Wolf, Eckhard (2017): The Munich MIDY Pig Biobank - A unique resource for studying organ crosstalk in diabetes. In: Molecular Metabolism, Vol. 6, No. 8: pp. 931-940

Bougas, Anthony; Vlachogiannis, Ioannis A.; Gatos, Dimitrios; Arenz, Stefan; Dinos, George P. (2017): Dual effect of chloramphenicol peptides on ribosome inhibition. In: Amino Acids, Vol. 49, No. 5: pp. 995-1004

Brockmann, Markus; Blomen, Vincent A.; Nieuwenhuis, Joppe; Stickel, Elmer; Raaben, Matthijs; Bleijerveld, Onno B.; Altelaar, A. F. Maarten; Jae, Lucas T.; Brummelkamp, Thijn R. (2017): Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling. In: Nature, Vol. 546, No. 7657: pp. 307-311

Bröckl, S.; Krebs, S.; Varadharajan, A.; Straubinger, R. K.; Blum, H.; Büttner, M. (2017): Investigation of intra-herd spread of Mycobacterium caprae in cattle by generation and use of a whole-genome sequence. In: Veterinary Research Communications, Vol. 41, No. 2: pp. 113-128

Brönner, Cornelia; Salvi, Luca; Zocco, Manuel; Ugolini, Ilaria; Halic, Mario (2017): Accumulation of RNA on chromatin disrupts heterochromatic silencing. In: Genome Research, Vol. 27, No. 7: pp. 1174-1183

Böttcher, Ralph T.; Veelders, Maik; Rombaut, Pascaline; Faix, Jan; Theodosiou, Marina; Stradal, Theresa E.; Rottner, Klemens; Zent, Roy; Herzog, Franz ORCID: 0000-0001-8270-1449; Faessler, Reinhard (2017): Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading. In: Journal of Cell Biology, Vol. 216, No. 11: pp. 3785-3798

Cheng, Jingdong; Kellner, Nikola; Berninghausen, Otto; Hurt, Ed; Beckmann, Roland (2017): 3.2-angstrom-resolution structure of the 90S preribosome before A1 pre-rRNA cleavage. In: Nature Structural & Molecular Biology, Vol. 24, No. 11: pp. 954-964

Cheng, Jun; Maier, Kerstin C.; Avsec, Ziga; Rus, Petra; Gagneur, Julien (2017): Cis-regulatory elements explain most of the mRNA stability variation across genes in yeast. In: Rna, Vol. 23, No. 11: pp. 1648-1659

Costanzi, M.; Krupka, C.; Kischel, R.; Kufer, P.; Köhnke, T.; Spiekermann, K.; Hiddemann, W.; Subklewe, M. (2017): Secretion Of Soluble Factors By AML Cells Influence CD33/CD3 BITE (R) Antibody Mediated Cytotoxicity And T-Cell Proliferation. In: Haematologica, Vol. 102: pp. 357-358

Czogalla, Katrin J.; Biswas, Arijit; Höning, Klara; Hornung, Veit; Liphardt, Kerstin; Watzka, Matthias; Oldenburg, Johannes (2017): Warfarin and vitamin K compete for binding to Phe55 in human VKOR. In: Nature Structural & Molecular Biology, Vol. 24, No. 1: pp. 77-85

Decker, Tim-Michael; Kluge, Michael; Krebs, Stefan; Shah, Nilay; Blum, Helmut; Friedel, Caroline C.; Eick, Dirk (2017): Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of small molecule inhibitor JQ1. In: Scientific Reports, Vol. 7, 1684 [PDF, 1MB]

Douglass, Amelia M.; Kucukdereli, Hakan; Ponserre, Marion; Markovic, Milica; Gründemann, Jan; Strobel, Cornelia; Morales, Pilar L. Alcala; Conzelmann, Karl-Klaus; Lüthi, Andreas; Klein, Rüdiger (2017): Central amygdala circuits modulate food consumption through a positive-valence mechanism. In: Nature Neuroscience, Vol. 20, No. 10: pp. 1384-1394

Drexler, David Jan; Müller, Martina; Rojas-Cordova, Carlos Alberto; Bandera, Adrian Maurice; Witte, Gregor (2017): Structural and Biophysical Analysis of the Soluble DHH/DHHA1-Type Phosphodiesterase TM1595 from Thermotoga maritima. In: Structure, Vol. 25, No. 12: pp. 1887-1897

Eichhorn, S.; Mendoza, A.; Prinzing, A.; Stroh, A.; Xinghai, L.; Polski, M.; Heller, M.; Lahm, H.; Wolf, E.; Lange, R.; Krane, M. (2017): Corpuls CPR Generates Higher Mean Arterial Pressure Than LUCAS II in a Pig Model of Cardiac Arrest. In: Biomed Research international, Vol. 2017, 5470406 [PDF, 2MB]

Engel, Christina; Brügmann, Grethe; Lambing, Silke; Mühlenbeck, Larissa H.; Marx, Samira; Hagen, Christian; Horvath, Dorottya; Goldeck, Marion; Ludwig, Janos; Herzner, Anna-Maria; Drijfhout, Jan W.; Wenzel, Daniela; Coch, Christoph; Tüting, Thomas; Schlee, Martin; Hornung, Veit; Hartmann, Gunther; Boorn, Jasper G. van den (2017): RIG-I Resists Hypoxia-Induced Immunosuppression and Dedifferentiation. In: Cancer Immunology Research, Vol. 5, No. 6: pp. 455-467

Farias-Rico, Jose Arcadio; Götz, Sara Kathrin; Marino, Jacopo; Heijne, Gunnar von (2017): Mutational analysis of protein folding inside the ribosome exit tunnel. In: Febs Letters, Vol. 591, No. 1: pp. 155-163

Flenkenthaler, F.; Schmid, N.; Froehlich, T.; Dietrich, K.; Schwarzer, J. U.; Mayerhofer, A.; Arnold, G. J. (2017): Quantitative proteomics reveals cellular senescence of human testicular peritubular cells. In: Reproduction in Domestic Animals, Vol. 52: p. 17

Florin, Tanja; Maracci, Cristina; Graf, Michael; Karki, Prajwal; Klepacki, Dorota; Berninghausen, Otto; Beckmann, Roland; Vazquez-Laslop, Nora; Wilson, Daniel N.; Rodnina, Marina V.; Mankin, Alexander S. (2017): An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome. In: Nature Structural & Molecular Biology, Vol. 24, No. 9: pp. 752-757

Florin, Tanja; Maracci, Cristina; Graf, Michael; Karki, Prajwal; Klepacki, Dorota; Rodnina, Marina V.; Wilson, Daniel N.; Vazquez-Laslop, Nora; Mankin, Alexander S. (2017): Antimicrobial Peptide Turns the Ribosome into a Release Factor Trap. In: FASEB Journal, Vol. 31

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Graf, S. A.; Heppt, M. V.; Krebs, S.; Kammerbauer, C.; Hornig, E.; Strieder, A.; Blum, H.; Berking, C. (2017): Peripheral myelin protein 2 is a target gene of the transcription factor SOX10 in melanoma and affects tumor cell invasion. In: Experimental Dermatology, Vol. 26, No. 3, E91-E92

Göbel, J.; Ghanem, A.; Motori, E.; Jahn, H. M.; Wani, G.; Conzelmann, K.-K.; Bergami, M. (2017): Perivascular remodeling of astrocytic ER and mitochondrial networks following brain injury. In: Glia, Vol. 65, E526-E526

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Hambaryan, V.; Suleimanov, V.; Haberl, F.; Schwope, A. D.; Neuhäuser, R.; Hohle, M.; Werner, K. (2017): The compactness of the isolated neutron star RX J0720.4-3125. In: Astronomy & Astrophysics, Vol. 601, A108

Hedegger, K.; Krebs, S.; Graf, A.; Kunzelmann, S.; Blum, H.; Wolf, E.; Dahlhoff, M. (2017): Peri-conceptional overweight in male and female mice causes sex-specific transcriptome changes in blastocysts which could result from differential expressed sncRNA in spermatozoa of obese males. In: Reproduction in Domestic Animals, Vol. 52: p. 22

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Heuer, Andre; Gerovac, Milan; Schmidt, Christian; Trowitzsch, Simon; Preis, Anne; Kötter, Peter; Berninghausen, Otto; Becker, Thomas; Beckmann, Roland; Tampe, Robert (2017): Structure of the 40S-ABCE1 post-splitting complex in ribosome recycling and translation initiation. In: Nature Structural & Molecular Biology, Vol. 24, No. 5: pp. 453-460

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