Number of items at this level: 565.
2022
Hohle, Markus Matthias; Lammens, Katja; Gut, Fabian; Wang, Bingzhi; Kahler, Sophia; Kugler, Kathrin; Till, Michael; Beckmann, Roland; Hopfner, Karl-Peter and Jung, Christophe
(12. September 2022):
Ice thickness monitoring for cryo-EM grids by interferometry imaging.
In: Scientific Reports, Vol. 12
[PDF, 2MB]
Kunert, Franziska; Metzner, Felix J.; Jung, James; Höpfler, Markus; Woike, Stephan; Schall, Kevin; Kostrewa, Dirk; Moldt, Manuela; Chen, Jia-Xuan; Bantele, Susanne; Pfander, Boris; Eustermann, Sebastian and Hopfner, Karl-Peter
(2022):
Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
In: Science Advances, Vol. 8, No. 49
[PDF, 3MB]
Qi, Zhan; Jung, Christophe; Bandilla, Peter; Ludwig, Claudia; Heron, Mark; Sophie Kiesel, Anja; Museridze, Mariam; Philippou‐Massier, Julia; Nikolov, Miroslav; Renna Max Schnepf, Alessio; Unnerstall, Ulrich; Ceolin, Stefano; Mühlig, Bettina; Gompel, Nicolas; Soeding, Johannes and Gaul, Ulrike
(14. February 2022):
Large‐scale analysis of Drosophila core promoter function using synthetic promoters.
In: Molecular Systems Biology, Vol. 18, No. 2
[PDF, 3MB]
Stafford, Che A.; Gassauer, Alicia-Marie; Oliveira Mann, Carina C. de; Tanzer, Maria C.
ORCID: https://orcid.org/0000-0002-4657-9869; Fessler, Evelyn; Wefers, Benedikt
ORCID: https://orcid.org/0000-0002-2492-9389; Nagl, Dennis; Kuut, Gunnar; Sulek, Karolina; Vasilopoulou, Catherine; Schwojer, Sophia J.
ORCID: https://orcid.org/0000-0002-1747-4144; Wiest, Andreas
ORCID: https://orcid.org/0000-0003-2525-6304; Pfautsch, Marie K.; Wurst, Wolfgang
ORCID: https://orcid.org/0000-0003-4422-7410; Yabal, Monica
ORCID: https://orcid.org/0000-0003-3495-7671; Fröhlich, Thomas
ORCID: https://orcid.org/0000-0002-4709-3211; Mann, Matthias
ORCID: https://orcid.org/0000-0003-1292-4799; Gisch, Nicolas
ORCID: https://orcid.org/0000-0003-3260-5269; Jae, Lucas T.
ORCID: https://orcid.org/0000-0002-3531-1760 and Hornung, Veit
ORCID: https://orcid.org/0000-0002-4150-194X
(2022):
Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation.
In: Nature, Vol. 609: pp. 590-596
[PDF, 10MB]
2021
Alminana, Carmen; Rudolf Vegas, Alba; Tekin, Muhittin; Hassan, Mubbashar; Uzbekov, Rustem; Frohlich, Thomas; Bollwein, Heinrich and Bauersachs, Stefan
(2021):
Isolation and Characterization of Equine Uterine Extracellular Vesicles: A Comparative Methodological Study.
In: International Journal of Molecular Sciences, Vol. 22, No. 2, 979
Altstetter, Sebastian Maximilian; Quitt, Oliver; Pinci, Francesca; Hornung, Veit; Lucko, Aaron Michael; Wisskirchen, Karin; Jung, Stephanie and Protzer, Ulrike
(2021):
Hepatitis-D Virus Infection Is Not Impaired by Innate Immunity but Increases Cytotoxic T-Cell Activity.
In: Cells, Vol. 10, No. 11, 3253
Brandt, Margot; Kim-Hellmuth, Sarah; Ziosi, Marcello; Gokden, Alper; Wolman, Aaron; Lam, Nora; Recinos, Yocelyn; Daniloski, Zharko; Morris, John A.; Hornung, Veit; Schumacher, Johannes and Lappalainen, Tuuli
(2021):
An autoimmune disease risk variant: A trans master regulatory effect mediated by IRF1 under immune stimulation?
In: PLOS Genetics
17(7), e1009684
Caballero, Ignacio; Ringot-Destrez, Belinda; Si-Tahar, Mustapha; Barbry, Pascal; Guillon, Antoine; Lantier, Isabelle; Berri, Mustapha; Chevaleyre, Claire; Fleurot, Isabelle; Barc, Celine; Ramphal, Reuben; Pons, Nicolas; Paquet, Agnes; Lebrigand, Kevin; Baron, Carole; Baehr, Andrea; Klymiuk, Nikolai; Leonard, Renaud and Robbe-Masselot, Catherine
(2021):
Evidence of early increased sialylation of airway mucins and defective mucociliary clearance in CFTR-deficient piglets.
In: Journal of Cystic Fibrosis, Vol. 20, No. 1: pp. 173-182
Ghosh, Suvoshree; Kraus, Katrin; Biswas, Arijit; Mueller, Jens; Forin, Francesco; Singer, Heike; Höning, Klara; Hornung, Veit; Watzka, Matthias; Oldenburg, Johannes and Czogalla-Nitsche, Katrin J.
(2021):
GGCX variants leading to biallelic deficiency to gamma-carboxylate GRP cause skin laxity in VKCFD1 patients.
In: Human Mutation, Vol. 43, No. 1: pp. 42-55
Ghosh, Suvoshree; Kraus, Katrin; Biswas, Arijit; Müller, Jens; Buhl, Anna-Lena; Forin, Francesco; Singer, Heike; Höning, Klara; Hornung, Veit; Watzka, Matthias; Czogalla-Nitsche, Katrin J. and Oldenburg, Johannes
(2021):
GGCX mutations show different responses to vitamin K thereby determining the severity of the hemorrhagic phenotype in VKCFD1 patients.
In: Journal of Thrombosis and Haemostasis, Vol. 19, No. 6: pp. 1412-1424
Hnizda, Ales; Tesina, Petr; Nguyen, Thanh-Binh; Kukacka, Zdenek; Kater, Lukas; Chaplin, Amanda; Beckmann, Roland; Ascher, David B.; Novak, Petr and Blundell, Tom L.
(2021):
SAP domain forms a flexible part of DNA aperture in Ku70/80.
In: Febs Journal, Vol. 288, No. 14: pp. 4382-4393
Huang, Bin; Guo, Qiang; Niedermeier, Marie L.; Cheng, Jingdong; Engler, Tatjana; Maurer, Melanie; Pautsch, Alexander; Baumeister, Wolfgang; Stengel, Florian; Kochanek, Stefan and Fernandez-Busnadiego, Ruben
(2021):
Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex.
In: Structure, Vol. 29, No. 8: pp. 804-809
Kirstein, Nina; Buschle, Alexander; Wu, Xia; Krebs, Stefan; Blum, Helmut; Kremmer, Elisabeth; Vorberg, Ina M.; Hammerschmidt, Wolfgang; Lacroix, Laurent; Hyrien, Olivier; Audit, Benjamin and Schepers, Aloys
(2021):
Human ORC/MCM density is low in active genes and correlates with replication time but does not delimit initiation zones.
In: eLife, Vol. 10, e62161
[PDF, 1MB]
Kratzat, Hanna; Mackens‐Kiani, Timur; Ameismeier, Michael; Potocnjak, Mia; Cheng, Jingdong; Dacheux, Estelle; Namane, Abdelkader; Berninghausen, Otto; Herzog, Franz
ORCID: https://orcid.org/0000-0001-8270-1449; Fromont‐Racine, Micheline; Becker, Thomas and Beckmann, Roland
(2021):
A structural inventory of native ribosomal ABCE1‐43S pre‐initiation complexes.
In: EMBO, Vol. 40, No. 1
[PDF, 12MB]
Lenz, Jonathan; Liefke, Robert; Funk, Julianne; Shoup, Samuel; Nist, Andrea; Stiewe, Thorsten; Schulz, Robert; Tokusumi, Yumiko; Albert, Lea; Raifer, Hartmann; Foerstemann, Klaus; Vazquez, Olalla; Tokusumi, Tsuyoshi; Fossett, Nancy and Brehm, Alexander
(2021):
Ush regulates hemocyte-specific gene expression, fatty acid metabolism and cell cycle progression and cooperates with dNuRD to orchestrate hematopoiesis.
In: PLOS Genetics
17(2), e1009318
Li, Xiaoling; Fetter, Richard; Schwabe, Tina; Jung, Christophe; Liu, Liren; Steller, Hermann and Gaul, Ulrike
(2021):
The cAMP effector PKA mediates Moody GPCR signaling in Drosophila blood-brain barrier formation and maturation.
In: eLife, Vol. 10, e68275
[PDF, 13MB]
Linnekamp, Janneke F.; Kandimalla, Raju; Fessler, Evelyn; Jong, Joan H. de; Rodermond, Hans M.; Bochove, Gregor G. W. van; The, Frans O.; Punt, Cornelis J. A.; Bemelman, Willem A.; Ven, Anthony W. H. van de; Tanis, Pieter J.; Kemper, Elles M.; Koens, Lianne; Dekker, Evelien; Vermeulen, Louis; Laarhoven, Hanneke W. M. van and Medema, Jan Paul
(2021):
Pre-Operative Decitabine in Colon Cancer Patients: Analyses on WNT Target Methylation and Expression.
In: Cancers, Vol. 13, No. 10, 2357
Liu, Zikou; Dagley, Laura F.; Shield-Artin, Kristy; Young, Samuel N.; Bankovacki, Aleksandra; Wang, Xiangyi; Tang, Michelle; Howitt, Jason; Stafford, Che A.; Nachbur, Ueli; Fitzgibbon, Cheree; Garnish, Sarah E.; Webb, Andrew I.; Komander, David; Murphy, James M.; Hildebrand, Joanne M. and Silke, John
(2021):
Oligomerization-driven MLKL ubiquitylation antagonizes necroptosis.
In: EMBO Journal, Vol. 40, No. 23, e103718
Mertes, Christian; Scheller, Ines F.; Yepez, Vicente A.; Celik, Muhammed H.; Liang, Yingjiqiong; Kremer, Laura S.; Gusic, Mirjana; Prokisch, Holger and Gagneur, Julien
(2021):
Detection of aberrant splicing events in RNA-seq data using FRASER.
In: Nature Communications, Vol. 12, No. 1, 529
Oberbeckmann, Elisa; Niebauer, Vanessa; Watanabe, Shinya; Farnung, Lucas; Moldt, Manuela; Schmid, Andrea; Cramer, Patrick; Peterson, Craig L.; Eustermann, Sebastian; Hopfner, Karl-Peter and Korber, Philipp
(2021):
Ruler elements in chromatin remodelers set nucleosome array spacing and phasing.
In: Nature Communications, Vol. 12, No. 1, 3232
Pochopien, Agnieszka A.; Beckert, Bertrand; Kasvandik, Sergo; Berninghausen, Otto; Beckmann, Roland; Tenson, Tanel and Wilson, Daniel N.
(2021):
Structure of Gcn1 bound to stalled and colliding 80S ribosomes.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, No. 14, e2022756118
Rabanal-Ruiz, Yoana; Byron, Adam; Wirth, Alexander; Madsen, Ralitsa; Sedlackova, Lucia; Hewitt, Graeme; Nelson, Glyn; Stingele, Julian; Wills, Jimi C.; Zhang, Tong; Zeug, Andre; Faessler, Reinhard; Vanhaesebroeck, Bart; Maddocks, Oliver D. K.; Ponimaskin, Evgeni; Carroll, Bernadette and Korolchuk, Viktor
(2021):
mTORC1 activity is supported by spatial association with focal adhesions.
In: Journal of Cell Biology, Vol. 220, No. 5, e202004010
Shashikadze, Bachuki; Flenkenthaler, Florian; Stöckl, Jan B.; Valla, Libera; Renner, Simone; Kemter, Elisabeth; Wolf, Eckhard and Fröhlich, Thomas
(2021):
Developmental Effects of (Pre-)Gestational Diabetes on Offspring: Systematic Screening Using Omics Approaches.
In: Genes, Vol. 12, No. 12, 1991
Shen, Lunda; Su, Zhaoming; Yang, Kailu; Wu, Cheng; Becker, Thomas; Bell-Pedersen, Deborah; Zhang, Junjie and Sachs, Matthew S.
(2021):
Structure of the translating Neurospora ribosome arrested by cycloheximide.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, No. 48, e2111862118
Stakyte, K.; Rotheneder, M.; Lammens, K.; Bartho, J. D.; Grädler, U.; Fuchß, T.; Pehl, U.; Alt, A.; Logt, E. van de and Hopfner, K. P.
(2021):
Molecular basis of human ATM kinase inhibition.
In: Nature Structural & Molecular Biology, Vol. 28, No. 10: 789-
Tahk, Siret; Vick, Binje; Hiller, Björn; Schmitt, Saskia; Marcinek, Anetta; Perini, Enrico D.; Leutbecher, Alexandra; Augsberger, Christian; Reischer, Anna; Tast, Benjamin; Humpe, Andreas; Jeremias, Irmela; Subklewe, Marion; Fenn, Nadja C. and Hopfner, Karl-Peter
(2021):
SIRP alpha-alpha CD123 fusion antibodies targeting CD123 in conjunction with CD47 blockade enhance the clearance of AML-initiating cells.
In: Journal of Hematology & Oncology, Vol. 14, No. 1, 155
Tahk, Siret; Vick, Binje; Hiller, Björn; Schmitt, Saskia; Marcinek, Anetta; Perini, Enrico D.; Leutbecher, Alexandra; Augsberger, Christian; Reischer, Anna; Tast, Benjamin; Humpe, Andreas; Jeremias, Irmela; Subklewe, Marion; Fenn, Nadja C. and Hopfner, Karl-Peter
ORCID: https://orcid.org/0000-0002-4528-8357
(2021):
SIRPα-αCD123 fusion antibodies targeting CD123 in conjunction with CD47 blockade enhance the clearance of AML-initiating cells.
In: Journal of hematology & oncology, Vol. 14, 155
[PDF, 3MB]
Trotter, Benjamin; Wilde, Magdalena; Brehm, Julian; Dafni, Evdokia; Aliu, Arlinda; Arnold, Georg J.; Fröhlich, Thomas and Laforsch, Christian
(2021):
Long-term exposure of Daphnia magna to polystyrene microplastic (PS-MP) leads to alterations of the proteome, morphology and life-history.
In: Science of the Total Environment, Vol. 795, 148822
Wratil, Paul R.; Schmacke, Niklas A.; Karakoc, Burak; Dulovic, Alex; Junker, Daniel; Becker, Matthias; Rothbauer, Ulrich; Osterman, Andreas; Spaeth, Patricia M.; Ruhle, Adrian; Gapp, Madeleine; Schneider, Stephanie; Muenchhoff, Maximilian; Hellmuth, Johannes C.; Scherer, Clemens; Mayerle, Julia; Reincke, Martin; Behr, Jürgen; Kaab, Stefan; Zwissler, Bernhard; Bergwelt-Baildon, Michael von; Eberle, Josef; Kaderali, Lars; Schneiderhan-Marra, Nicole; Hornung, Veit and Keppler, Oliver T.
(2021):
Evidence for increased SARS-CoV-2 susceptibility and COVID-19 severity related to pre-existing immunity to seasonal coronaviruses.
In: Cell Reports, Vol. 37, No. 13, 110169
Yepez, Vicente A.; Mertes, Christian; Mueller, Michaela F.; Klaproth-Andrade, Daniela; Wachutka, Leonhard; Fresard, Laure; Gusic, Mirjana; Scheller, Ines F.; Goldberg, Patricia F.; Prokisch, Holger and Gagneur, Julien
(2021):
Detection of aberrant gene expression events in RNA sequencing data.
In: Nature Protocols, Vol. 16, No. 2
Zhao, Shubo; Kieser, Anja; Li, Hao-Yi; Reinking, Hannah K.; Weickert, Pedro; Euteneuer, Simon; Yaneva, Denitsa; Acampora, Aleida C.; Goetz, Maximilian J.; Feederle, Regina and Stingele, Julian
(2021):
A ubiquitin switch controls autocatalytic inactivation of the DNA-protein crosslink repair protease SPRTN.
In: Nucleic Acids Research, Vol. 49, No. 2
2020
Basu, Aakash; Bobrovnikov, Dmitriy G.; Qureshi, Zan; Kayikcioglu, Tunc; Ngo, Thuy T. M.; Ranjan, Anand; Eustermann, Sebastian; Cieza, Basilio; Morgan, Michael T.; Hejna, Miroslav; Rube, H. Tomas; Hopfner, Karl-Peter; Wolberger, Cynthia; Song, Jun S. and Ha, Taekjip
(2020):
Measuring DNA mechanics on the genome scale.
In: Nature, Vol. 589, No. 7842: pp. 462-467
Blagotinsek, Vitan; Schwan, Meike; Steinchen, Wieland; Mrusek, Devid; Hook, John C.; Rossmann, Florian; Freibert, Sven A.; Kratzat, Hanna; Murat, Guillaume; Kressler, Dieter; Beckmann, Roland; Beeby, Morgan; Thormann, Kai M. and Bange, Gert
(2020):
An ATP-dependent partner switch links flagellar C-ring assembly with gene expression.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 34: pp. 20826-20835
Brea, Deborah; Soler, Laura; Fleurot, Isabelle; Melo, Sandrine; Chevaleyre, Claire; Berri, Mustapha; Labas, Valerie; Teixeira-Gomes, Ana-Paula; Pujo, Julien; Cenac, Nicolas; Baehr, Andrea; Klymiuk, Nikolai; Guillon, Antoine; Si-Tahar, Mustapha and Caballero, Ignacio
(2020):
Intrinsic alterations in peripheral neutrophils from cystic fibrosis newborn piglets.
In: Journal of Cystic Fibrosis, Vol. 19, No. 5: pp. 830-836
Buschauer, Robert; Matsuo, Yoshitaka; Sugiyama, Takato; Chen, Ying-Hsin; Alhusaini, Najwa; Sweet, Thomas; Ikeuchi, Ken; Cheng, Jingdong; Matsuki, Yasuko; Nobuta, Risa; Gilmozzi, Andrea; Berninghausen, Otto; Tesina, Petr; Becker, Thomas; Coller, Jeff; Inada, Toshifumi and Beckmann, Roland
(2020):
The Ccr4-Not complex monitors the translating ribosome for codon optimality.
In: Science, Vol. 368, No. 6488, eaay6912
Ceolin, Stefano; Hanf, Monika; Bozek, Marta; Storti, Andrea Ennio; Gompel, Nicolas; Unnerstall, Ulrich; Jung, Christophe and Gaul, Ulrike
(2020):
A sensitive mNeonGreen reporter system to measure transcriptional dynamics in Drosophila development.
In: Communications Biology, Vol. 3, No. 1, 663
Cunha Bustamante-Filho, Ivan; Renato Menegassi, Silvio; Ribas Pereira, Gabriel; Dias Salton, Gabrielle; Mosena Munari, Fernanda; Roberto Schneider, Marlon; Costa Mattos, Rodrigo; Otavio Jardim Barcellos, Julio; Pereira Laurino, Jomar; Obino Cirne-Lima, Elizabeth and Ines Mascarenhas Jobim, Maria
(2020):
Bovine seminal plasma osteopontin: Structural modelling, recombinant expression and its relationship with semen quality.
In: Andrologia, Vol. 53, No. 1, e13905
Fessler, Evelyn; Eckl, Eva-Maria; Schmitt, Sabine; Mancilla, Igor Alves; Meyer-Bender, Matthias F.; Hanf, Monika; Philippou-Massier, Julia; Krebs, Stefan; Zischka, Hans and Jae, Lucas T.
(2020):
A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol.
In: Nature, Vol. 579, No. 7799: pp. 433-437
Gegenfurtner, Katrin; Fröhlich, Thomas; Flenkenthaler, Florian; Koesters, Miwako; Fritz, Sebastien; Desnoes, Olivier; Le Bourhis, Daniel; Salvetti, Pascal; Sandra, Olivier; Charpigny, Gilles; Mermillod, Pascal; Lonergan, Patrick; Wolf, Eckhard and Arnold, Georg J.
(2020):
Genetic merit for fertility alters the bovine uterine luminal fluid proteome.
In: Biology of Reproduction, Vol. 102, No. 3: pp. 730-739
Ghodgaonkar-Steger, Medini; Potocnjak, Mia; Zimniak, Tomasz; Fischböck-Halwachs, Josef; Solis-Mezarino, Victor; Singh, Sylvia; Speljko, Tea; Hagemann, Götz; Drexler, David Jan; Witte, Gregor and Herzog, Franz
ORCID: https://orcid.org/0000-0001-8270-1449
(2020):
C-Terminal Motifs of the MTW1 Complex Cooperatively Stabilize Outer Kinetochore Assembly in Budding Yeast.
In: Cell reports, Vol. 32, No. 13, 108190
[PDF, 5MB]
Hinrichs, Arne; Riedel, Evamaria O.; Klymiuk, Nikolai; Blutke, Andreas; Kemter, Elisabeth; Laengin, Matthias; Dahlhoff, Maik; Kessler, Barbara; Kurome, Mayuko; Zakhartchenko, Valeri; Jemiller, Eva-Maria; Ayares, David; Bidlingmaier, Martin; Flenkenthaler, Florian; Hrabe de Angelis, Martin; Arnold, Georg J.; Reichart, Bruno; Fröhlich, Thomas and Wolf, Eckhard
(2020):
Growth hormone receptor knockout to reduce the size of donor pigs for preclinical xenotransplantation studies.
In: Xenotransplantation, Vol. 28, No. 2, e12664
Hoesl, Christine; Zanuttigh, Enrica; Fröhlich, Thomas; Philippou-Massier, Julia; Krebs, Stefan; Blum, Helmut and Dahlhoff, Maik
(2020):
The secretome of skin cancer cells activates the mTOR/MYC pathway in healthy keratinocytes and induces tumorigenic properties.
In: Biochimica et Biophysica Acta-Molecular Cell Research, Vol. 1867, No. 8, 118717
Huppertz, Christine; Jager, Benedikt; Wieczorek, Grazyna; Engelhard, Peggy; Oliver, Stephen J.; Bauernfeind, Franz-Georg; Littlewood-Evans, Amanda; Welte, Tobias; Hornung, Veit and Prasse, Antje
(2020):
The NLRP3 inflammasome pathway is activated in sarcoidosis and involved in granuloma formation.
In: European Respiratory Journal, Vol. 55, No. 3, 1900119
Jansma, Marijke; Linke-Winnebeck, Christian; Eustermann, Sebastian; Lammens, Katja; Kostrewa, Dirk; Stakyte, Kristina; Litz, Claudia; Kessler, Brigitte and Hopfner, Karl-Peter
(2020):
Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State.
In: Structure, Vol. 28, No. 1: pp. 83-95
Killinger, Kerstin; Boehm, Miriam; Steinbach, Philine; Hagemann, Goetz; Blueggel, Mike; Jaenen, Karolin; Hohoff, Simone; Bayer, Peter; Herzog, Franz and Westermann, Stefan
(2020):
Auto-inhibition of Mif2/CENP-C ensures centromere-dependent kinetochore assembly in budding yeast.
In: EMBO Journal, Vol. 39, No. 14, e102938
Koepke, Lennart; Winter, Benjamin; Grenzner, Alexander; Regensburger, Kerstin; Engelhart, Susanne; Merwe, Johannes A. van der; Krebs, Stefan; Blum, Helmut; Kirchhoff, Frank and Sparrer, Konstantin M. J.
(2020):
An improved method for high-throughput quantification of autophagy in mammalian cells.
In: Scientific Reports, Vol. 10, No. 1, 12241
[PDF, 6MB]
Kratzat, Hanna; Mackens-Kiani, Timur; Ameismeier, Michael; Potocnjak, Mia; Cheng, Jingdong; Dacheux, Estelle; Namane, Abdelkader; Berninghausen, Otto; Herzog, Franz; Fromont-Racine, Micheline; Becker, Thomas and Beckmann, Roland
(2020):
A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
In: EMBO Journal, Vol. 40, No. 1, e105179
Lampl, Sandra; Janas, Marianne K.; Donakonda, Sainitin; Brugger, Marcus; Lohr, Kerstin; Schneider, Annika; Manske, Katrin; Sperl, Laura E.; Klaeger, Susan; Kuester, Bernhard; Wettmarshausen, Jennifer; Müller, Constanze; Laschinger, Melanie; Hartmann, Daniel; Hueser, Norber; Perocchi, Fabiana; Schmitt-Kopplin, Philippe; Hagn, Franz; Zender, Lars; Hornung, Veit; Borner, Christoph; Pichlmair, Andreas; Kashkar, Hamid; Klingenspor, Martin; Prinz, Marco; Schreiner, Sabrina; Conrad, Marcus; Jost, Philipp J.; Zischka, Hans; Steiger, Katja; Kroenke, Martin; Zehn, Dietmar; Protzer, Ulrike; Heikenwaelder, Mathias; Knolle, Percy A. and Wohlleber, Dirk
(2020):
Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes.
In: Journal of Hepatology, Vol. 73, No. 6: pp. 1347-1359
Latoscha, Andreas; Drexler, David Jan; Al-Bassam, Mahmoud M.; Bandera, Adrian M.; Kaever, Volkhard; Findlay, Kim C.; Witte, Gregor and Tschowri, Natalia
(2020):
c-di-AMP hydrolysis by the phosphodiesterase AtaC promotes differentiation of multicellular bacteria.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 13: pp. 7392-7400
Lauterbach-Riviere, Lise; Bergez, Maiwenn; Moench, Saskia; Qu, Bingqian; Riess, Maximilian; Vondran, Florian W. R.; Liese, Juliane; Hornung, Veit; Urban, Stephan and König, Renate
(2020):
Hepatitis B Virus DNA is a Substrate for the cGAS/STING Pathway but is not Sensed in Infected Hepatocytes.
In: Viruses-Basel, Vol. 12, No. 6, 592
Limbrick, Emilianne M.; Graf, Michael; Derewacz, Dagmara K.; Nguyen, Fabian; Spraggins, Jeffrey M.; Wieland, Maximiliane; Ynigez-Gutierrez, Audrey E.; Reisman, Benjamin J.; Zinshteyn, Boris; McCulloch, Kathryn M.; Iverson, T. M.; Green, Rachel; Wilson, Daniel N. and Bachmann, Brian O.
(2020):
Bifunctional Nitrone-Conjugated Secondary Metabolite Targeting the Ribosome.
In: Journal of the American Chemical Society, Vol. 142, No. 43: pp. 18369-18377
Linder, Andreas; Bauernfried, Stefan; Cheng, Yiming; Albanese, Manuel; Jung, Christophe; Keppler, Oliver T. and Hornung, Veit
(2020):
CARD8 inflammasome activation triggers pyroptosis in human T cells.
In: EMBO Journal, Vol. 39, No. 19, e105071
[PDF, 1MB]
Loregger, Anke; Raaben, Matthijs; Nieuwenhuis, Joppe; Tan, Josephine M. E.; Jae, Lucas T.; Hengel, Lisa G. van den; Hendrix, Sebastian; Berg, Marlene van den; Scheij, Saskia; Song, Ji-Ying; Huijbers, Ivo J.; Kroese, Lona J.; Ottenhoff, Roelof; Weeghel, Michel van; Sluis, Bart van de; Brummelkamp, Thijn and Zelcer, Noam
(2020):
Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism.
In: Nature Communications, Vol. 11, No. 1, 1128
[PDF, 3MB]
Lucienne, Marie; Aguilar-Pimentel, Juan Antonio; Amarie, Oana V.; Becker, Lore; Calzada-Wack, Julia; Silva-Buttkus, Patricia da; Garrett, Lillian; Holter, Sabine M.; Mayer-Kuckuk, Philipp; Rathkolb, Birgit; Rozman, Jan; Spielmann, Nadine; Treise, Irina; Busch, Dirk H.; Klopstock, Thomas; Schmidt-Weber, Carsten; Wolf, Eckhard; Wurst, Wolfgang; Forny, Merima; Mathis, Deborah; Fingerhut, Ralph; Froese, D. Sean; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin and Baumgartner, Matthias R.
(2020):
In-depth phenotyping reveals common and novel disease symptoms in a hemizygous knock-in mouse model (Mut-ko/ki) of mut-type methylmalonic aciduria.
In: Biochimica et Biophysica Acta-Molecular Basis of Disease, Vol. 1866, No. 3, 165622
Margos, Gabriele; Fedorova, Natalia; Becker, Noemie S.; Kleinjan, Joyce E.; Marosevic, Durdica; Krebs, Stefan; Hui, Lucia; Fingerle, Volker and Lane, Robert S.
(2020):
Borrelia maritima sp. nov., a novel species of the Borrelia burgdorferi sensu tato complex, occupying a basal position to North American species.
In: International Journal of Systematic and Evolutionary Microbiology, Vol. 70, No. 2: pp. 849-856
Matsuo, Yoshitaka; Tesina, Petr; Nakajima, Shizuka; Mizuno, Masato; Endo, Akinori; Buschauer, Robert; Cheng, Jingdong; Shounai, Okuto; Ikeuchi, Ken; Saeki, Yasushi; Becker, Thomas; Beckmann, Roland and Inada, Toshifumi
(2020):
RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1.
In: Nature Structural & Molecular Biology, Vol. 27, No. 4: pp. 323-332
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The In Situ Structure of Parkinson's Disease-Linked LRRK2.
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Dosage Compensation of the X Chromosomes in Bovine Germline, Early Embryos, and Somatic Tissues.
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TLR8 Is a Sensor of RNase T2 Degradation Products.
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Cytosolic Gram-negative bacteria prevent apoptosis by inhibition of effector caspases through lipopolysaccharide.
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A conserved ATP- and Scc2/4-dependent activity for cohesin in tethering DNA molecules.
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NOD Signaling and Cell Death.
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The transmembrane protein LRIG2 increases tumor progression in skin carcinogenesis.
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First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study.
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A mouse model for intellectual disability caused by mutations in the X-linked 2 '-O-methyltransferase Ftsj1 gene.
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TMEM16A in Cystic Fibrosis: Activating or Inhibiting?
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KMT9 monomethylates histone H4 lysine 12 and controls proliferation of prostate cancer cells.
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SLFN11 can sensitize tumor cells towards IFN-gamma-mediated T cell killing.
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A novel approach to study the bovine oviductal fluid proteome using transvaginal endoscopy.
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Cytoplasmic RNA Sensor Pathways and Nitazoxanide Broadly Inhibit Intracellular Mycobacterium tuberculosis Growth.
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Detection of collagens by multispectral optoacoustic tomography as an imaging biomarker for Duchenne muscular dystrophy.
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Structural adaptations of photosynthetic complex I enable ferredoxin-dependent electron transfer.
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IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell.
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CRN2 binds to TIMP4 and MMP14 and promotes perivascular invasion of glioblastoma cells.
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DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity.
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Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia.
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A conserved filamentous assembly underlies the structure of the meiotic chromosome axis.
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Identification of Rabbit Oviductal Fluid Proteins Involved in Pre-Fertilization Processes by Quantitative Proteomics.
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Identification of the fructose transporter GLUT5 (SLC2A5) as a novel target of nuclear receptor LXR.
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The antiviral activity of rodent and lagomorph SERINC3 and SERINC5 is counteracted by known viral antagonists.
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Learning-Related Plasticity in Dendrite-Targeting Layer 1 Interneurons.
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Thirty-eight-negative kinase 1 mediates trauma-induced intestinal injury and multi-organ failure.
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A folding nucleus and minimal ATP binding domain of Hsp70 identified by single-molecule force spectroscopy.
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Dual-targeting triplebody 33-16-123 (SPM-2) mediates effective redirected lysis of primary blasts from patients with a broad range of AML subtypes in combination with natural killer cells.
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Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum.
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OUTRIDER: A Statistical Method for Detecting Aberrantly Expressed Genes in RNA Sequencing Data.
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Prediction of Adipose Browning Capacity by Systematic Integration of Transcriptional Profiles.
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Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity.
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The heterozygous R155C VCP mutation: Toxic in humans! Harmless in mice?
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Transcriptional programming of lipid and amino acid metabolism by the skeletal muscle circadian clock.
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Comparative genomics and the nature of placozoan species.
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The wide utility of rabbits as models of human diseases.
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Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.
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Anatomical projections of the dorsomedial hypothalamus to the periaqueductal grey and their role in thermoregulation: a cautionary note.
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Genome wide association analysis in a mouse advanced intercross line.
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Somatic alterations compromised molecular diagnosis of DOCK8 hyper-IgE syndrome caused by a novel intronic splice site mutation.
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Bifunctional PD-1 x alpha CD3 x alpha CD33 fusion protein reverses adaptive immune escape in acute myeloid leukemia.
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Dilution correction for dynamically influenced urinary analyte data.
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Ribonucleotide Excision Repair Is Essential to Prevent Squamous Cell Carcinoma of the Skin.
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Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liver.
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Oxeiptosis, a ROS-induced caspase-independent apoptosis-like cell-death pathway.
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Human immunodeficiency virus 1 dual-target nucleic acid technology improves blood safety: 5 years of experience of the German Red Cross blood donor service Baden-Wiirttemberg-Hessen.
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Total Synthesis and Structural Revision of the Antibiotic Tetrapeptide GE81112A.
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True equilibrium measurement of transcription factor-DNA binding affinities using automated polarization microscopy.
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Animal models of obesity and diabetes mellitus.
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Faim2 contributes to neuroprotection by erythropoietin in transient brain ischemia.
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Human TGF-beta 1 deficiency causes severe inflammatory bowel disease and encephalopathy.
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Targeting LAG-3 and PD-1 to Enhance T Cell Activation by Antigen-Presenting Cells.
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Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models.
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IPEX due to an exon 7 skipping FOXP3 mutation with autoimmune diabetes mellitus cured by selective T-Reg cell engraftment.
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Modeling lethal X-linked genetic disorders in pigs with ensured fertility.
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Effects of single and combined low frequency electromagnetic fields and simulated microgravity on gene expression of human mesenchymal stem cells during chondrogenesis.
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A myosin II nanomachine mimicking the striated muscle.
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A paternal methyl donor-rich diet altered cognitive and neural functions in offspring mice.
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Structural and functional analysis of Erwinia amylovora SrlD. The first crystal structure of a sorbitol-6-phosphate 2-dehydrogenase.
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Targeting tumor cell plasticity by combined inhibition of NOT CH and MAPK signaling in colon cancer.
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Single-molecule nucleosome remodeling by INO80 and effects of histone tails.
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Affinity switching of the LEDGF/p75 IBD interactome is governed by kinase-dependent phosphorylation.
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Targeting de novo lipogenesis as a novel approach in anti-cancer therapy.
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Activation of the NLRP3 Inflammasome by Hyaboron, a New Asymmetric Boron-Containing Macrodiolide from the Myxobacterium Hyalangium minutum.
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Suppressor mutations in Rpf2-Rrs1 or Rpl5 bypass the Cgr1 function for pre-ribosomal 5S RNP-rotation.
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Folding pathway of an Ig domain is conserved on and off the ribosome.
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A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and Type 2 diabetes.
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Xie, Kan; Ryan, Devon P.; Pearson, Brandon L.; Henzel, Kristin S.; Neff, Frauke; Vidal, Ramon O.; Hennion, Magali; Lehmann, Isabelle; Schleif, Melvin; Schröder, Susanne; Adler, Thure; Rathkolb, Birgit; Rozman, Jan; Schütz, Anna-Lena; Prehn, Cornelia; Mickael, Michel E.; Weiergraber, Marco; Adamski, Jerzy; Busch, Dirk H.; Ehninger, Gerhard; Matynia, Anna; Jackson, Walker S.; Wolf, Eckhard; Fuchs, Helmut; Gailus-Durner, Valerie; Bonn, Stefan; Hrabe de Angelis, Martin and Ehninger, Dan
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Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring mice.
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OCR-Stats: Robust estimation and statistical testing of mitochondrial respiration activities using Seahorse XF Analyzer.
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cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein-DNA ladders.
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Dr Patrick Baeuerle, MPMCapital, talks with young scientists.
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Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening.
In: Molecular Cell, Vol. 67, No. 4: pp. 711-723
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Antibodies against the mono-methylated arginine-glycine repeat (MMA-RG) of the Epstein-Barr virus nuclear antigen 2 (EBNA2) identify potential cellular proteins targeted in viral transformation.
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Genome-wide Analysis of RNA Polymerase II Termination at Protein-Coding Genes.
In: Molecular Cell, Vol. 66, No. 1: pp. 38-49
Bauersachs, Stefan; Simintiras, Constantine A.; Sturmey, Roger G.; Krebs, Stefan; Bick, Jochen; Blum, Helmut; Wolf, Eckhard; Lonergan, Pat and Forde, Niamh
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Effect of metabolic status on conceptus-maternal interactions on day 19 in dairy cattle: II. Effects on the endometrial transcriptome.
In: Biology of Reproduction, Vol. 97, No. 3: pp. 413-425
Baum, Rebecca; Sharma, Shruti; Organ, Jason M.; Jakobs, Christopher; Hornung, Veit; Burr, David B.; Marshak-Rothstein, Ann; Fitzgerald, Katherine A. and Gravallese, Ellen M.
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STING Contributes to Abnormal Bone Formation Induced by Deficiency of DNase II in Mice.
In: Arthritis & Rheumatology, Vol. 69, No. 2: pp. 460-471
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Structure of the Bacillus subtilis hibernating 100S ribosome reveals the basis for 70S dimerization.
In: Embo Journal, Vol. 36, No. 14: pp. 2061-2072
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Mechanism of Enzyme Repair by the AAA(+) Chaperone Rubisco Activase.
In: Molecular Cell, Vol. 67, No. 5: pp. 744-756
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ADNP Is a Therapeutically Inducible Repressor of WNT Signaling in Colorectal Cancer.
In: Clinical Cancer Research, Vol. 23, No. 11: pp. 2769-2780
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The Munich MIDY Pig Biobank - A unique resource for studying organ crosstalk in diabetes.
In: Molecular Metabolism, Vol. 6, No. 8: pp. 931-940
Brockmann, Markus; Blomen, Vincent A.; Nieuwenhuis, Joppe; Stickel, Elmer; Raaben, Matthijs; Bleijerveld, Onno B.; Altelaar, A. F. Maarten; Jae, Lucas T. and Brummelkamp, Thijn R.
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Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling.
In: Nature, Vol. 546, No. 7657: pp. 307-311
Böttcher, Ralph T.; Veelders, Maik; Rombaut, Pascaline; Faix, Jan; Theodosiou, Marina; Stradal, Theresa E.; Rottner, Klemens; Zent, Roy; Herzog, Franz
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Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading.
In: Journal of Cell Biology, Vol. 216, No. 11: pp. 3785-3798
Decker, Tim-Michael; Kluge, Michael; Krebs, Stefan; Shah, Nilay; Blum, Helmut; Friedel, Caroline C. and Eick, Dirk
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Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of small molecule inhibitor JQ1.
In: Scientific Reports, Vol. 7, 1684
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Central amygdala circuits modulate food consumption through a positive-valence mechanism.
In: Nature Neuroscience, Vol. 20, No. 10: pp. 1384-1394
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Corpuls CPR Generates Higher Mean Arterial Pressure Than LUCAS II in a Pig Model of Cardiac Arrest.
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RIG-I Resists Hypoxia-Induced Immunosuppression and Dedifferentiation.
In: Cancer Immunology Research, Vol. 5, No. 6: pp. 455-467
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An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome.
In: Nature Structural & Molecular Biology, Vol. 24, No. 9: pp. 752-757
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Antimicrobial Peptide Turns the Ribosome into a Release Factor Trap.
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The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3.
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EBF1 binds to EBNA2 and promotes the assembly of EBNA2 chromatin complexes in B cells.
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Peripheral myelin protein 2 is a target gene of the transcription factor SOX10 in melanoma and affects tumor cell invasion.
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Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic T(H)17 cells.
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The novel MKL target gene myoferlin modulates expansion and senescence of hepatocellular carcinoma.
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Prediction of Primary Refractory Acute Myeloid Leukemia.
In: Annals of Hematology, Vol. 96: S25-S25
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Structure of the 40S-ABCE1 post-splitting complex in ribosome recycling and translation initiation.
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Cryo-EM structure of a late pre-40S ribosomal subunit from Saccharomyces cerevisiae.
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Prolonged IKK beta Inhibition Improves Ongoing CTL Antitumor Responses by Incapacitating Regulatory T Cells.
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Diabetes Mellitus-Induced Microvascular Destabilization in the Myocardium.
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Impaired weight gain and disproportionate organ growth, but preserved fertility in growth hormone receptor deficient pigs (Laron syndrome).
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SK2 channels regulate mitochondrial respiration and mitochondrial Ca2+ uptake.
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Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P.
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Karakatsani, Andromachi; Marichal, Nicolas; Urban, Severino; Kalamakis, Georgios; Ghanem, Alexander; Schick, Anna; Zhang, Yina; Conzelmann, Karl-Klaus; Rüegg, Markus A.; Berninger, Benedikt; Ruiz de Almodovar, Carmen; Gascon, Sergio and Kröger, Stephan
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Neuronal LRP4 regulates synapse formation in the developing CNS.
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Polysialic acid blocks mononuclear phagocyte reactivity, inhibits complement activation, and protects from vascular damage in the retina.
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Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
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Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations.
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Genetic diagnosis of Mendelian disorders via RNA sequencing.
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Myticalins: A Novel Multigenic Family of Linear, Cationic Antimicrobial Peptides from Marine Mussels (Mytilus spp.).
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Leth, Christoph; Varadharajan, Ashok; Mester, Patrick; Fischaleck, Marlis; Rossmanith, Peter; Schmoll, Friedrich and Fink, Maria
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Matrixlysis, an improved sample preparation method for recovery of Mycobacteria from animal tissue material.
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Lost in plasmids: next generation sequencing and the complex genome of the tick-borne pathogen Borrelia burgdorferi.
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B3GALNT2 mutations associated with non-syndromic autosomal recessive intellectual disability reveal a lack of genotype-phenotype associations in the muscular dystrophy-dystroglycanopathies.
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Ubiquitination of stalled ribosome triggers ribosome-associated quality control.
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Whole-genome analysis of introgressive hybridization and characterization of the bovine legacy of Mongolian yaks.
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Impact of metabolic status and genetic merit for fertility on proteomic composition of bovine oviduct fluid.
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Identification of CMTM6 and CMTM4 as PD-L1 protein regulators.
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Structure of the RZZ complex and molecular basis of its interaction with Spindly.
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Structure of the RZZ complex and molecular basis of its interaction with Spindly.
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Cotranslational folding of spectrin domains via partially structured states.
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Costimulation Increases Intracellular Signalling In Bite (R) Antibody Construct Mediated T-Cell Activation.
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SIRP alpha-antibody fusion proteins stimulate phagocytosis and promote elimination of acute myeloid leukemia cells.
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NRP2 and CD63 Are Host Factors for Lujo Virus Cell Entry.
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The Region of Difference Four is a Robust Genetic Marker for Subtyping Mycobacteriumcaprae Isolates and is Linked to Spatial Distribution of Three Subtypes.
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SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia.
In: Nature Medicine, Vol. 23, No. 2: pp. 250-255
Silva, P.; Neumann, M.; Schroeder, M. P.; Vosberg, S.; Schlee, C.; Isaakidis, K.; Ortiz-Tanchez, J.; Fransecky, L. R.; Hartung, T.; Türkmen, S.; Graf, A.; Krebs, S.; Blum, H.; Müller-Tidow, C.; Thiede, C.; Ehninger, G.; Serve, H.; Hecht, J.; Berdel, W. E.; Greif, P. A.; Röllig, C. and Baldus, C. D.
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Acute myeloid leukemia in the elderly is characterized by a distinct genetic and epigenetic landscape.
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A Poly-ADP-Ribose Trigger Releases the Auto-Inhibition of a Chromatin Remodeling Oncogene.
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Slowinska, M.; Nynca, J.; Arnold, G. J.; Fröhlich, T.; Jankowski, J.; Kozlowski, K.; Mostek, A. and Ciereszko, A.
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Proteomic identification of turkey (Meleagris gallopavo) seminal plasma proteins.
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The force-sensing peptide VemP employs extreme compaction and secondary structure formation to induce ribosomal stalling.
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Molecular basis for asymmetry sensing of siRNAs by the Drosophila Loqs-PD/Dcr-2 complex in RNA interference.
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Optogenetic control of mitochondrial metabolism and Ca2+ signaling by mitochondria-targeted opsins.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, No. 26, E5167-E5176
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Evolutionary Patterns of Cytogenetically Normal Acute Myeloid Leukemia Correlate with Time to Relapse.
In: Annals of Hematology, Vol. 96: S55-S55
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In-depth mutational analyses of colorectal neuroendocrine carcinomas with adenoma or adenocarcinoma components.
In: Modern Pathology, Vol. 30, No. 1: pp. 95-103
Ye, Qiaozhen; Kim, Dong Hyun; Dereli, Ihsan; Rosenberg, Scott C.; Hagemann, Götz; Herzog, Franz
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The AAA plus ATPase TRIP13 remodels HORMA domains through N-terminal engagement and unfolding.
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TNF alpha drives mitochondrial stress in POMC neurons in obesity.
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Temporal Control of Mammalian Cortical Neurogenesis by m(6)A Methylation.
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Tissue Sampling Guides for Porcine Biomedical Models.
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CCAN Assembly Configures Composite Binding Interfaces to Promote Cross-Linking of Ndc80 Complexes at the Kinetochore.
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Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome.
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Architecture of the Rix1-Rea1 checkpoint machinery during pre-60S-ribosome remodeling.
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Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry.
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Inflammasome-Dependent Induction of Adaptive NK Cell Memory.
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4D Visualization of replication foci in mammalian cells corresponding to individual replicons.
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The INSC94Y transgenic pig: a novel model for diabetic retinopathy with macular edema.
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Dynamic Behavior of Trigger Factor on the Ribosome.
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Exome sequencing identifies a nonsense mutation in Fam46a associated with bone abnormalities in a new mouse model for skeletal dysplasia.
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Determinants of RNA metabolism in the Schizosaccharomyces pombe genome.
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Determinants of RNA metabolism in the Schizosaccharomyces pombe genome.
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Atomic Structure and Biochemical Characterization of an RNA Endonuclease in the N Terminus of Andes Virus L Protein.
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Molecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP and Astrin.
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Human Monocytes Engage an Alternative Inflammasome Pathway.
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Structural mechanism for the recognition and ubiquitination of a single nucleosome residue by Rad6-Bre1.
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Structural mechanism for the recognition and ubiquitination of a single nucleosome residue by Rad6-Bre1.
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K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria.
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Meiotic Interactors of a Mitotic Gene TAO3 Revealed by Functional Analysis of its Rare Variant.
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Structural and functional insights into the fly microRNA biogenesis factor Loquacious.
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Modulations of DNA Contacts by Linker Histones and Post-translational Modifications Determine the Mobility and Modifiability of Nucleosomal H3 Tails.
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Improved cryotolerance and developmental potential of in vitro and in vivo matured mouse oocytes by supplementing with a glutathione donor prior to vitrification.
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A Combination of CRISPR/Cas9 and Standardized RNAi as a Versatile Platform for the Characterization of Gene Function.
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cGAMP transfers intercellularly via HIV-1 Env-mediated cell-cell fusion sites and triggers an innate immune response in primary target cells.
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cGAS-Mediated Innate Immunity Spreads Intercellularly through HIV-1 Env-Induced Membrane Fusion Sites.
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In: Embo Molecular Medicine, Vol. 6, No. 4: pp. 442-457
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Sydow, Jasmin F.; Lipsmeier, Florian; Larraillet, Vincent; Hilger, Maximiliane; Mautz, Björn; Mølhøj,, Michael; Kuentzer, Jan; Klostermann, Stefan; Schoch, Jürgen; Voelger, Hans R.; Regula, Jörg T.; Cramer, Patrick; Papadimitriou, Apollon and Kettenberger, Hubert
(2014):
Structure-Based Prediction of Asparagine and Aspartate Degradation Sites in Antibody Variable Regions.
In: PLOS ONE
9(6), e100736
[PDF, 1MB]
Wickles, Stephan; Singharoy, Abhishek; Andreani, Jessica; Seemayer, Stefan; Bischoff, Lukas; Berninghausen, Otto; Soeding, Johannes; Schulten, Klaus; Sluis, Eli O. van der and Beckmann, Roland
(2014):
A structural model of the active ribosome-bound membrane protein insertase YidC.
In: eLife, Vol. 3, e03035
[PDF, 3MB]
2013
Lammens, Alfred; Baehner, Monika; Kohnert, Ulrich; Niewoehner, Jens; Proff, Leopold von; Schraeml, Michael; Lammens, Katja and Hopfner, Karl-Peter
(2013):
Crystal Structure of Human TWEAK in Complex with the Fab Fragment of a Neutralizing Antibody Reveals Insights into Receptor Binding.
In: PLOS ONE
8(5), e62697
[PDF, 1MB]
2012
Mohr, Hermine; Mohr, Christian A.; Schneider, Marlon R.; Scrivano, Laura; Adler, Barbara; Kraner-Scheiber, Simone; Schnieke, Angelika; Dahlhoff, Maik; Wolf, Eckhard; Koszinowski, Ulrich H. and Ruzsics, Zsolt
(2012):
Cytomegalovirus replicon-based regulation of gene expression in vitro and in vivo.
In: PLOS Pathogens
8(6), e1002728
[PDF, 2MB]
Niederberger, Theresa; Etzold, Stefanie; Lidschreiber, Michael; Maier, Kerstin C.; Martin, Dietmar E.; Fröhlich, Holger; Cramer, Patrick and Tresch, Achim
(2012):
MC EMiNEM maps the interaction landscape of the Mediator.
In: PLOS Computational Biology
8(6), e1002568
[PDF, 775kB]
2011
2008
1991
1988
1986
1985
1984
1983
1982
1980
Braunitzer, Gerdard; Schrank, Barbara; Stangl, Anton and Wiesner, Henning
(1980):
Respiration at High Altitudes, Phosphate-Protein-Interaction: Sequence of the Hemoglobins of the Hamster (Mesocricetus aureatus) and the Camel (Camelus ferus, Camelidae)., Höhenatmung, Phosphat-Protein-Wechselwirkung: Die Sequenz der Hämoglobine des Goldhamsters (Mesocricetus aureatus) und des zweihöckerigen Kamels (Trampeltier, Camelus ferus, Camelidae).
In: Journal of the Chemical Society of Pakistan, Vol. 2, No. 1: pp. 1-7
[PDF, 775kB]
1979
This list was generated on Wed Dec 6 18:39:02 2023 CET.