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Ellwart, Mario; Höfner, Georg; Gerwien, Aaron; Wanner, Klaus T.; Knochel, Paul (2017): Synthesis and Bioactivity of Novel N-Benzylic and N-Phenethylic Ephedrine Derivatives. In: Synthesis-Stuttgart, Vol. 49, Nr. 23: S. 5159-5166
Volltext auf 'Open Access LMU' nicht verfügbar.

Abstract

A range of N-benzylic and N-phenethylic ephedrine derivatives were prepared in a one-pot procedure starting from the two enantiomers of ephedrine using the Potier reagent, and a polyfunctional aryl-or benzylic organozinc halide. The biological activity in indatraline MS Binding Assays addressing hDAT, hNET and hSERT was determined and discussed.