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Number of items at this level: 329.

2019

Gentiluomo, Lorenzo; Roessner, Dierk; Augustijn, Dillen; Svilenov, Hristo ORCID: 0000-0001-5863-9569; Kulakova, Alina; Mahapatra, Sujata; Winter, Gerhard; Streicher, Werner; Rinnan, Asmund; Peters, Günther; Harris, Pernille; Friess, Wolfgang (August 2019): Application of interpretable artificial neural networks to early monoclonal antibodies development. In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 141: pp. 81-89 [PDF, 1MB]

Svilenov, Hristo ORCID: 0000-0001-5863-9569; Winter, Gerhard (1. May 2019): Rapid sample-saving biophysical characterisation and long-term storage stability of liquid interferon alpha2a formulations Is there a correlation? In: International Journal of Pharmaceutics, Vol. 562: pp. 42-50 [PDF, 1MB]

Svilenov, Hristo ORCID: 0000-0001-5863-9569; Winter, Gerhard (April 2019): The ReFOLD assay for protein formulation studies and prediction of protein aggregation during long-term storage. In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 137: pp. 131-139 [PDF, 2MB]

2018

Andima, Moses; Costabile, Gabriella; Isert, Lorenz; Ndakala, Albert J.; Derese, Solomon; Merkel, Olivia M. (2018): Evaluation of beta-Sitosterol Loaded PLGA and PEG-PLA Nanoparticles for Effective Treatment of Breast Cancer: Preparation, Physicochemical Characterization, and Antitumor Activity. In: Pharmaceutics, Vol. 10, No. 4, 232

Berger, Karin; Schopohl, Dorothee; Bollig, Antonia; Strobach, Dorothea; Rieger, Christina; Rublee, Dale; Ostermann, Helmut (2018): Burden of Oral Mucositis: A Systematic Review and Implications for Future Research. In: Oncology Research and Treatment, Vol. 41, No. 6: pp. 399-405

Blank, Thomas; Goldmann, Tobias; Koch, Mirja; Amann, Lukas; Schön, Christian; Bonin, Michael; Pang, Shengru; Prinz, Marco; Burnet, Michael; Wagner, Johanna E.; Biel, Martin; Michalakis, Stylianos (2018): Early Microglia Activation Precedes Photoreceptor Degeneration in a Mouse Model of CNGB1-Linked Retinitis Pigmentosa. In: Frontiers in Immunology, Vol. 8, 1930

Bracher, Franz (2018): Methods for Arylethylation of Amines and Heteroarenes. In: Synopen, Vol. 2, No. 2: pp. 96-104

Braig, Simone (2018): Chemical genetics in tumor lipogenesis. In: Biotechnology Advances, Vol. 36, No. 6: pp. 1724-1729

Burkard, Markus; Kohl, Susanne; Kratzig, Timm; Tanimoto, Naoyuki; Brennenstuhl, Christina; Bausch, Anne E.; Junger, Katrin; Reuter, Peggy; Sothilingam, Vithiyanjali; Beck, Susanne C.; Huber, Gesine; Ding, Xi-Qin; Mayer, Anja K.; Baumann, Britta; Weisschuh, Nicole; Zobor, Ditta; Hahn, Gesa-Astrid; Kellner, Ulrich; Venturelli, Sascha; Becirovic, Elvir; Charbel Issa, Peter; Koenekoop, Robert K.; Rudolph, Gunther; Heckenlively, John; Sieving, Paul; Weleber, Richard G.; Hamel, Christian; Zong, Xiangang; Biel, Martin; Lukowski, Robert; Seeliger, Matthias W.; Michalakis, Stylianos; Wissinger, Bernd; Ruth, Peter (2018): Accessory heterozygous mutations in cone photoreceptor CNGA3 exacerbate CNG channel-associated retinopathy. In: The Journal of Clinical Investigation, Vol. 128, No. 12: pp. 5663-5675

Chatzopoulou, E. I.; Raharja-Liu, P.; Murschhauser, A.; Sekhavati, F.; Buggenthin, F.; Vollmar, A. M.; Marr, C.; Rädler, J. O. (2018): A single-cell micro-trench platform for automatic monitoring of cell division and apoptosis after chemotherapeutic drug administration. In: Scientific Reports, Vol. 8, 18042

Costabile, Gabriella; Gasteyer, Kathrin I.; Nadithe, Venkatereddy; Denburgh, Katherine van; Lin, Qian; Sharma, Shiv; Reineke, Joshua J.; Firestine, Steven M.; Merkel, Olivia M. (2018): Physicochemical and In Vitro Evaluation of Drug Delivery of an Antibacterial Synthetic Benzophenone in Biodegradable PLGA Nanoparticles. In: Aaps Pharmscitech, Vol. 19, No. 8: pp. 3561-3570

Deglmann, Claus J.; Blazkow-Schmalzbauer, Katarzyna; Moorkamp, Sarah; Wallmichrath, Jens; Giunta, Riccardo E.; Rogach, Andrey L.; Wagner, Ernst; Baumeister, Rüdiger G.; Ogris, Manfred (2018): In vivo tracking of adipose tissue grafts with cadmium-tel-luride quantum dots. In: Archives of Plastic Surgery-Aps, Vol. 45, No. 2: pp. 111-117

Dileep, Kalarickal V.; Remya, Chandran; Tintu, Ignatius; Mandal, Pradeep K.; Karthe, Ponnuraj; Haridas, Madathilkovilakathu; Sadasivan, Chittalakkottu (2018): Crystal structure of phospholipase A(2) in complex with 1-naphthaleneacetic acid. In: Iubmb Life, Vol. 70, No. 10: pp. 995-1001

Engelke, Laura; Winter, Gerhard; Engert, Julia (2018): Application of water-soluble polyvinyl alcohol-based film patches on laser microporated skin facilitates intradermal macromolecule and nanoparticle delivery. In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 128: pp. 119-130

Engert, Julia; Anamur, Cihad; Engelke, Laura; Fellner, Christian; Lell, Peter; Henke, Stefan; Stadler, Julia; Zoels, Susanne; Ritzmann, Mathias; Winter, Gerhard (2018): A pilot study using a novel pyrotechnically driven prototype applicator for epidermal powder immunization in piglets. In: International Journal of Pharmaceutics, Vol. 545, No. 1-2: pp. 215-228

Falk, Nathalie; Kessler, Kristin; Schramm, Sinja-Fee; Boldt, Karsten; Becirovic, Elvir; Michalakis, Stylianos; Regus-Leidig, Hanna; Noegel, Angelika A.; Ueffing, Marius; Thiel, Christian T.; Roepman, Ronald; Brandstaetter, Johann Helmut; Giessl, Andreas (2018): Functional analyses of Pericentrin and Syne-2 interaction in ciliogenesis. In: Journal of Cell Science, Vol. 131, No. 16

Feldmann, Daniel P.; Cheng, Yilong; Kandil, Rima; Xie, Yuran; Mohammadi, Mariam; Harz, Hartmann; Sharma, Akhil; Peeler, David J.; Moszczynska, Anna; Leonhardt, Heinrich; Pun, Suzie H.; Merkel, Olivia M. (2018): In vitro and in vivo delivery of siRNA via VIPER polymer system to lung cells. In: Journal of Controlled Release, Vol. 276: pp. 50-58

Ferrand, Yann; Huc, Ivan (2018): Designing Helical Molecular Capsules Based on Folded Aromatic Amide Oligomers. In: Accounts of Chemical Research, Vol. 51, No. 4: pp. 970-977

Gegenfurtner, Florian A.; Jahn, Berenice; Wagner, Helga; Ziegenhain, Christoph; Enard, Wolfgang; Geistlinger, Ludwig; Rädler, Joachim O.; Vollmar, Angelika M.; Zahler, Stefan (2018): Micropatterning as a tool to identify regulatory triggers and kinetics of actin-mediated endothelial mechanosensing. In: Journal of Cell Science, Vol. 131, No. 10

Gegenfurtner, Florian A.; Zisis, Themistoklis; Al Danaf, Nader; Schrimpf, Waldemar; Kliesmete, Zane; Ziegenhain, Christoph; Enard, Wolfgang; Kazmaier, Uli; Lamb, Don C.; Vollmar, Angelika M.; Zahler, Stefan (2018): Transcriptional effects of actin-binding compounds: the cytoplasm sets the tone. In: Cellular and Molecular Life Sciences, Vol. 75, No. 24: pp. 4539-4555

Geh, Katharina J.; Hubert, Madlen; Winter, Gerhard (2018): Progress in formulation development and sterilisation of freeze-dried oligodeoxynucleotide-loaded gelatine nanoparticles. In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 129: pp. 10-20

Gemechu, Jickssa M.; Sharma, Akhil; Yu, Dongyue; Xie, Yuran; Merkel, Olivia M.; Moszczynska, Anna (2018): Characterization of Dopaminergic System in the Striatum of Young Adult Park2(-/-) Knockout Rats. In: Scientific Reports, Vol. 8, 1517

Gitter, Julian H.; Geidobler, Raimund; Presser, Ingo; Winter, Gerhard (2018): A Comparison of Controlled Ice Nucleation Techniques for Freeze-Drying of a Therapeutic Antibody. In: Journal of Pharmaceutical Sciences, Vol. 107, No. 11: pp. 2748-2754

Gitter, Julian H.; Geidobler, Raimund; Presser, Ingo; Winter, Gerhard (2018): Significant Drying Time Reduction Using Microwave- Assisted Freeze- Drying for a Monoclonal Antibody. In: Journal of Pharmaceutical Sciences, Vol. 107, No. 10: pp. 2538-2543

Gronauer, Thomas F.; Mandl, Melanie M.; Lakemeyer, Markus; Hackl, Mathias W.; Messner, Martina; Korotkov, Vadim S.; Pachmayr, Johanna; Sieber, Stephan A. (2018): Design and synthesis of tailored human caseinolytic protease P inhibitors. In: Chemical Communications, Vol. 54, No. 70: pp. 9833-9836

Haeuser, Christina; Goldbach, Pierre; Huwyler, Jörg; Friess, Wolfgang; Allmendinger, Andrea (2018): Imaging Techniques to Characterize Cake Appearance of Freeze-Dried Products. In: Journal of Pharmaceutical Sciences, Vol. 107, No. 11: pp. 2810-2822

Hager, Simone; Wagner, Ernst (2018): Bioresponsive polyplexes - chemically programmed for nucleic acid delivery. In: Expert Opinion on Drug Delivery, Vol. 15, No. 11: pp. 1067-1083

Hauke, Tobias J.; Wein, Thomas; Hofner, Georg; Wanner, Klaus T. (2018): Novel Allosteric Ligands of gamma-Aminobutyric Acid Transporter 1 (GAT1) by MS Based Screening of Pseudostatic Hydrazone Libraries. In: Journal of Medicinal Chemistry, Vol. 61, No. 22: pp. 10310-10332

Hirschberger, Kristin; Jarzebinska, Anita; Kessel, Eva; Kretzschmann, Verena; Aneja, Manish K.; Dohmen, Christian; Herrmann-Janson, Annika; Wagner, Ernst; Plank, Christian; Rudolph, Carsten (2018): Exploring Cytotoxic mRNAs as a Novel Class of Anti-cancer Biotherapeutics. In: Molecular Therapy-Methods & Clinical Development, Vol. 8: pp. 141-151

Horn, Jacqueline; Friess, Wolfgang (2018): Detection of Collapse and Crystallization of Saccharide, Protein, and Mannitol Formulations by Optical Fibers in Lyophilization. In: Frontiers in Chemistry, Vol. 6, 4

Horn, Jacqueline; Schanda, Julia; Friess, Wolfgang (2018): Impact of fast and conservative freeze-drying on product quality of protein-mannitol-sucrose-glycerol lyophilizates. In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 127: pp. 342-354

Horn, Jacqueline; Tolardo, Eleonora; Fissore, Davide; Friess, Wolfgang (2018): Crystallizing amino acids as bulking agents in freeze-drying. In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 132: pp. 70-82

Huber, Simone K.; Höfner, Georg; Wanner, Klaus T. (2018): Identification of Pyrrolidine-3-acetic Acid Derived Oximes as Potent Inhibitors of gamma-Aminobutyric Acid Transporter 1 through Library Screening with MS Binding Assays. In: Chemmedchem, Vol. 13, No. 23: pp. 2488-2503

Hubler, Zita; Allimuthu, Dharmaraja; Bederman, Ilya; Elitt, Matthew S.; Madhavan, Mayur; Allan, Kevin C.; Shick, H. Elizabeth; Garrison, Eric; Karl, Molly T.; Factor, Daniel C.; Nevin, Zachary S.; Sax, Joel L.; Thompson, Matthew A.; Fedorov, Yuriy; Jin, Jing; Wilson, William K.; Giera, Martin; Bracher, Franz; Miller, Robert H.; Tesar, Paul J.; Adams, Drew J. (2018): Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination. In: Nature, Vol. 560, No. 7718: pp. 372-376

Jones, Steven K.; Douglas, Kirk; Shields, Anthony F.; Merkel, Olivia M. (2018): Correlating quantitative tumor accumulation and gene knockdown using SPECT/CT and bioluminescence imaging within an orthotopic ovarian cancer model. In: Biomaterials, Vol. 178: pp. 183-192

Kappler, Sarah; Karmann, Lisa; Prudel, Cynthia; Herrmann, Jennifer; Caddeu, Giulia; Müller, Rolf; Vollmar, Angelika M.; Zahler, Stefan; Kazmaier, Uli (2018): Synthesis and Biological Evaluation of Modified Miuraenamides. In: European Journal of Organic Chemistry, No. 48: pp. 6952-6965

Kiesel, Esther Katharina; Hopf, Yvonne Marina; Drey, Michael (2018): An anticholinergic burden score for German prescribers: score development. In: BMC Geriatrics, Vol. 18, 239

Klein, D.; Kessler, W.; Pütz, C.; Semder, B.; Kirchinger, W.; Langsch, A.; Gries, W.; Otter, R.; Gallien, A. K. E.; Wurzenberger, X.; Filser, J. G. (2018): Single ingestion of di-(2-propylheptyl) phthalate (DPHP) by male volunteers: DPHP in blood and its metabolites in blood and urine. In: Toxicology Letters, Vol. 294: pp. 105-115

Klein, Philipp Michael; Kern, Sarah; Lee, Dian-Jang; Schmaus, Johannes; Hoehn, Miriam; Gorges, Jan; Kazmaier, Uli; Wagner, Ernst (2018): Folate receptor-directed orthogonal click-functionalization of siRNA lipopolyplexes for tumor cell killing in vivo. In: Biomaterials, Vol. 178: pp. 630-642

Klein, Philipp Michael; Klinker, Kristina; Zhang, Wei; Kern, Sarah; Kessel, Eva; Wagner, Ernst; Barz, Matthias (2018): Efficient Shielding of Polyplexes Using Heterotelechelic Polysarcosines. In: Polymers, Vol. 10, No. 6, 689

Klier, John; Geis, Sabine; Steuer, Jeanette; Geh, Katharina; Reese, Sven; Fuchs, Sebastian; Müller, Ralf S.; Winter, Gerhard; Gehlen, Heidrun (2018): A comparison of nanoparticullate CpG immunotherapy with and without allergens in spontaneously equine asthma-affected horses, an animal model. In: Immunity Inflammation and Disease, Vol. 6, No. 1: pp. 81-96

Koepf, Ellen; Eisele, Simon; Schröder, Rudolf; Brezesinski, Gerald; Friess, Wolfgang (2018): Notorious but not understood: How liquid-air interfacial stress triggers protein aggregation. In: International Journal of Pharmaceutics, Vol. 537, No. 1-2: pp. 202-212

Koepf, Ellen; Richert, Manuela; Braunschweig, Björn; Schröder, Rudolf; Brezesinski, Gerald; Friess, Wolfgang (2018): Impact of formulation pH on physicochemical protein characteristics at the liquid-air interface. In: International Journal of Pharmaceutics, Vol. 541, No. 1-2: pp. 234-245

Koepf, Ellen; Schröder, Rudolf; Brezesinski, Gerald; Friess, Wolfgang (2018): The missing piece in the puzzle: Prediction of aggregation via the protein-protein interaction parameter A(2)*. In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 128: pp. 200-209

Krauss, Jürgen; Bracher, Franz (2018): Pharmacokinetic Enhancers (Boosters)-Escort for Drugs against Degrading Enzymes and Beyond. In: Scientia Pharmaceutica, Vol. 86, No. 4

Krogsaeter, Einar K.; Biel, Martin; Wahl-Schott, Christian; Grimm, Christian (2018): The protein interaction networks of mucolipins and two-pore channels. In: Biochimica et Biophysica Acta-Molecular Cell Research [Forthcoming]

Lachenmayr, Sarah J.; Berking, Sophie; Horns, Heidi; Strobach, Dorothea; Ostermann, Helmut; Berger, Karin (2018): Antifungal treatment in haematological and oncological patients: Need for quality assessment in routine care. In: Mycoses, Vol. 61, No. 7: pp. 464-471

Larkin, Caroline M.; Breen, Eamon P.; Tomaszewski, Krzysztof A.; Eisele, Simon; Radomski, Marek W.; Ryan, Thomas A.; Santos-Martinez, Maria-Jose (2018): Platelet microaggregation in sepsis examined by quartz crystal microbalance with dissipation technology. In: Platelets, Vol. 29, No. 3: pp. 301-304

Larkin, Caroline M.; Hante, Nadhim Kamil; Breen, Eamon P.; Tomaszewski, Krzysztof A.; Eisele, Simon; Radomski, Marek W.; Ryan, Thomas A.; Santos-Martinez, Maria-Jose (2018): Role of matrix metalloproteinases 2 and 9, toll-like receptor 4 and platelet-leukocyte aggregate formation in sepsis-associated thrombocytopenia.
In: PLOS One 13(5), e0196478

Lin, Hsiao-Chun Amy; Dean-Ben, Xose Luis; Reiss, Michael; Schöttle, Verena; Wahl-Schott, Christian A.; Efimov, Igor R.; Razansky, Daniel (2018): Ultrafast Volumetric Optoacoustic Imaging of Whole Isolated Beating Mouse Heart. In: Scientific Reports, Vol. 8, 14132

Ljepoja, Bojan; Garcia-Roman, Jonathan; Sommer, Ann-Katrin; Frohlich, Thomas; Arnold, Georg J.; Wagner, Ernst; Roidl, Andreas (2018): A proteomic analysis of an in vitro knock-out of miR-200c. In: Scientific Reports, Vol. 8, 6927

Lohrer, B.; Bracher, F. (2018): A convenient identification of carbamate-derived drug substances. In: Pharmazie, Vol. 73, No. 10: pp. 555-558

Lohrer, Bernhard; Bracher, Franz (2018): A short and divergent route to 2-alkenyl-4-quinolones. In: Tetrahedron Letters, Vol. 59, No. 40: pp. 3632-3635

Lucke, Matthias; Mottas, Ines; Herbst, Tina; Hotz, Christian; Roemer, Lin; Schierling, Martina; Herold, Heike M.; Slotta, Ute; Spinetti, Thibaud; Scheibel, Thomas; Winter, Gerhard; Bourquin, Carole; Engert, Julia (2018): Engineered hybrid spider silk particles as delivery system for peptide vaccines. In: Biomaterials, Vol. 172: pp. 105-115

Lutz, Toni; Wein, Thomas; Höfner, Georg; Pabel, Jörg; Eder, Matthias; Dine, Julien; Wanner, Klaus T. (2018): Development of New Photoswitchable Azobenzene Based gamma-Aminobutyric Acid (GABA) Uptake Inhibitors with Distinctly Enhanced Potency upon Photoactivation. In: Journal of Medicinal Chemistry, Vol. 61, No. 14: pp. 6211-6235

Maiaru, Maria; Morgan, Oakley B.; Mao, Tianqi; Breitsamer, Michaela; Bamber, Harry; Poehlmann, Max; Schmidt, Mathias V.; Winter, Gerhard; Hausch, Felix; Geranton, Sandrine M. (2018): The stress regulator FKBP51: a novel and promising druggable target for the treatment of persistent pain states across sexes. In: Pain, Vol. 159, No. 7: pp. 1224-1234

Mateus, Pedro; Wicher, Barbara; Ferrand, Yann; Huc, Ivan (2018): Carbohydrate binding through first- and second-sphere coordination within aromatic oligoamide metallofoldamers. In: Chemical Communications, Vol. 54, No. 40: pp. 5078-5081

Mehta, Aditi; Barreto, Guillermo (2018): Non-invasive approaches for lung cancer diagnosis. In: Indian Journal of Thoracic and Cardiovascular Surgery, Vol. 34, No. Suppl. 1: pp. 11-19

Melzer, Benedikt C.; Felber, Jan G.; Bracher, Franz (2018): Aminomethylation/hydrogenolysis as an alternative to direct methylation of metalated isoquinolines - a novel total synthesis of the alkaloid 7-hydroxy-6-methoxy-1-methylisoquinoline. In: Beilstein Journal of Organic Chemistry, Vol. 14: pp. 130-134

Moustakim, Moses; Riedel, Kerstin; Schuller, Marion; Gehring, Andre P.; Monteiro, Octovia P.; Martin, Sarah P.; Fedorov, Oleg; Heer, Jag; Dixon, Darren J.; Elkins, Jonathan M.; Knapp, Stefan; Bracher, Franz; Brennan, Paul E. (2018): Discovery of a novel allosteric inhibitor scaffold for polyadenosine-diphosphate-ribose polymerase 14 (PARP14) macrodomain 2. In: Bioorganic & Medicinal Chemistry, Vol. 26, No. 11: pp. 2965-2972

Müller, Christoph; Neugebauer, Thomas; Zill, Patrizia; Lass-Floerl, Cornelia; Bracher, Franz; Binder, Ulrike (2018): Sterol Composition of Clinically Relevant Mucorales and Changes Resulting from Posaconazole Treatment. In: Molecules, Vol. 23, No. 5, 1218

Neiens, Patrick; De Simone, Angela; Höfner, Georg; Wanner, Klaus T. (2018): Simultaneous Multiple MS Binding Assays for the Dopamine, Norepinephrine, and Serotonin Transporters. In: Chemmedchem, Vol. 13, No. 5: pp. 453-463

Neiens, Patrick; De Simone, Angela; Ramershoven, Anna; Höfner, Georg; Allmendinger, Lars; Wanner, Klaus T. (2018): Development and validation of an LC-ESI-MS/MS method for the quantification of D-84, reboxetine and citalopram for their use in MS Binding Assays addressing the monoamine transporters hDAT, hSERT and hNET. In: Biomedical Chromatography, Vol. 32, No. 7, e4231

Niessen, K. V.; Seeger, T.; Rappenglück, S.; Wein, T.; Höfner, G.; Wanner, K. T.; Thiermann, H.; Worek, F. (2018): In vitro pharmacological characterization of the bispyridinium non-oxime compound MB327 and its 2-and 3-regioisomers. In: Toxicology Letters, Vol. 293: pp. 190-197

Plesch, Eva; Chen, Cheng-Chang; Butz, Elisabeth; Rosato, Anna Scotto; Krogsaeter, Einar K.; Yinan, Hua; Bartel, Karin; Keller, Marco; Robaa, Dina; Teupser, Daniel; Holdt, Lesca M.; Vollmar, Angelika M.; Sippl, Wolfgang; Puertollano, Rosa; Medina, Diego; Biel, Martin; Wahl-Schott, Christian; Bracher, Franz; Grimm, Christian (2018): Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells. In: eLife, Vol. 7, e39720

Poehlmann, Max L.; Haeusl, Alexander S.; Harbich, Daniela; Balsevich, Georgia; Engelhardt, Clara; Feng, Xixi; Breitsamer, Michaela; Hausch, Felix; Winter, Gerhard; Schmidt, Mathias V. (2018): Pharmacological Modulation of the Psychiatric Risk Factor FKBP51 Alters Efficiency of Common Antidepressant Drugs. In: Frontiers in Behavioral Neuroscience, Vol. 12, 262

Rappenglück, Sebastian; Sichler, Sonja; Höfner, Georg; Wein, Thomas; Niessen, Karin V.; Seeger, Thomas; Paintner, Franz F.; Worek, Franz; Thiermann, Horst; Wanner, Klaus T. (2018): Synthesis of a Series of Non-Symmetric Bispyridinium and Related Compounds and Their Affinity Characterization at the Nicotinic Acetylcholine Receptor. In: Chemmedchem, Vol. 13, No. 24: pp. 2653-2663

Rappenglück, Sebastian; Sichler, Sonja; Höfner, Georg; Wein, Thomas; Niessen, Karin V.; Seeger, Thomas; Paintner, Franz F.; Worek, Franz; Thiermann, Horst; Wanner, Klaus T. (2018): Synthesis of a Series of Structurally Diverse MB327 Derivatives and Their Affinity Characterization at the Nicotinic Acetylcholine Receptor. In: Chemmedchem, Vol. 13, No. 17: pp. 1806-1816

Rarova, Lucie; Sedlak, David; Oklestkova, Jana; Steigerova, Jana; Liebl, Johanna; Zahler, Stefan; Bartunek, Petr; Kolar, Zdenek; Kohout, Ladislav; Kvasnica, Miroslav; Strnad, Miroslav (2018): The novel brassinosteroid analog BR4848 inhibits angiogenesis in human endothelial cells and induces apoptosis in human cancer cells in vitro. In: Journal of Steroid Biochemistry and Molecular Biology, Vol. 178: pp. 263-271

Reinhard, Sören; Wang, Yanfang; Dengler, Sebastian; Wagner, Ernst (2018): Precise Enzymatic Cleavage Sites for Improved Bioactivity of siRNA Lipo-Polyplexes. In: Bioconjugate Chemistry, Vol. 29, No. 11: pp. 3649-3657

Riedmayr, Lisa Maria; Böhm, Sybille; Michalakis, Stylianos; Becirovic, Elvir (2018): Construction and Cloning of Minigenes for in vivo Analysis of Potential Splice Mutations. In: Bio-Protocol, Vol. 8, No. 5, e2760

Rodrigues, Leticia; Raftopoulos, Konstantinos N.; Schmidt, Signe Tandrup; Schneider, Fabian; Dietz, Hendrik; Rades, Thomas; Franzyk, Henrik; Pedersen, Anders Elm; Papadakis, Christine M.; Christensen, Dennis; Winter, Gerhard; Foged, Camilla; Hubert, Madlen (2018): Immune responses induced by nano-self-assembled lipid adjuvants based on a monomycoloyl glycerol analogue after vaccination with the Chlamydia trachomatis major outer membrane protein. In: Journal of Controlled Release, Vol. 285: pp. 12-22

Rogers, Joseph M.; Kwon, Sunbum; Dawson, Simon J.; Mandal, Pradeep K.; Suga, Hiroaki; Huc, Ivan (2018): Ribosomal synthesis and folding of peptide-helical aromatic foldamer hybrids. In: Nature Chemistry, Vol. 10, No. 4: pp. 405-412

Saha, Subrata; Kauffmann, Brice; Ferrand, Yann; Huc, Ivan (2018): Selective Encapsulation of Disaccharide Xylobiose by an Aromatic Foldamer Helical Capsule. In: Angewandte Chemie-International Edition, Vol. 57, No. 41: pp. 13542-13546

Saller, Verena; Hediger, Constanze; Matilainen, Julia; Grauschopf, Ulla; Bechtold-Peters, Karoline; Mahler, Hanns-Christian; Friess, Wolfgang (2018): Influence of particle shedding from silicone tubing on antibody stability. In: Journal of Pharmacy and Pharmacology, Vol. 70, No. 5: pp. 675-685

Schargus, Marc; Werner, Benjamin P.; Geerling, Gerd; Winter, Gerhard (2018): Contamination of anti-vegf drugs for intravitreal injection. How Do Repackaging and Newly Developed Syringes Affect the Amount of Silicone Oil Droplets and Protein Aggregates? In: Retina-the Journal of Retinal and Vitreous Diseases, Vol. 38, No. 10: pp. 2088-2095

Scheffel, Corinna; Niessen, Karin V.; Rappenglück, Sebastian; Wanner, Klaus T.; Thiermann, Horst; Worek, Franz; Seeger, Thomas (2018): Counteracting desensitization of human alpha 7-nicotinic acetylcholine receptors with bispyridinium compounds as an approach against organophosphorus poisoning. In: Toxicology Letters, Vol. 293: pp. 149-156

Scheffel, Corinna; Niessen, Karin V.; Rappenglück, Sebastian; Wanner, Klaus. T.; Thiermann, Horst; Worek, Franz; Seeger, Thomas (2018): Electrophysiological investigation of the effect of structurally different bispyridinium non-oxime compounds on human alpha 7-nicotinic acetylcholine receptor activity-An in vitro structure-activity analysis. In: Toxicology Letters, Vol. 293: pp. 157-166

Scherer, Nicole; Marcsekova, Klaudia; Posset, Tobias; Winter, Gerhard (2018): Evaluation of stir-bar sorptive extraction coupled with thermal desorption GC-MS for the detection of leachables from polymer single use systems to drugs. In: Journal of Pharmaceutical and Biomedical Analysis, Vol. 152: pp. 66-73

Schug, Christina; Sievert, Wolfgang; Urnauer, Sarah; Müller, Andrea M.; Schmohl, Kathrin A.; Wechselberger, Alexandra; Schwenk, Nathalie; Lauber, Kirsten; Schwaiger, Markus; Multhoff, Gabriele; Wagner, Ernst; Nelson, Peter J.; Spitzweg, Christine (2018): External Beam Radiation Therapy Enhances Mesenchymal Stem Cell-Mediated Sodium-Iodide Symporter Gene Delivery. In: Human Gene Therapy, Vol. 29, No. 11: pp. 1287-1300

Sichler, S.; Höfner, G.; Rappenglück, S.; Wein, T.; Niessen, V.; Seeger, T.; Worek, F.; Thiermann, H.; Paintner, F.; Wanner, K. T. (2018): Development of MS Binding Assays targeting the binding site of MB327 at the nicotinic acetylcholine receptor. In: Toxicology Letters, Vol. 293: pp. 172-183

Singh, Amrita; Saha, Tanumoy; Begemann, Isabell; Ricker, Andrea; Nuesse, Harald; Thorn-Seshold, Oliver; Klingauf, Jürgen; Galic, Milos; Matis, Maja (2018): Polarized microtubule dynamics directs cell mechanics and coordinates forces during epithelial morphogenesis. In: Nature Cell Biology, Vol. 20, No. 10: pp. 1126-1133

Sommer, Ann-Katrin; Hermawan, Adam; Ljepoja, Bojan; Fröhlich, Thomas; Arnold, Georg J.; Wagner, Ernst; Roidl, Andreas (2018): A proteomic analysis of chemoresistance development via sequential treatment with doxorubicin reveals novel players in MCF-7 breast cancer cells. In: International Journal of Molecular Medicine, Vol. 42, No. 4: pp. 1987-1997

Steinborn, Benjamin; Truebenbach, Ines; Morys, Stephan; Laechelt, Ulrich; Wagner, Ernst; Zhang, Wei (2018): Epidermal growth factor receptor targeted methotrexate and small interfering RNA co-delivery. In: Journal of Gene Medicine, Vol. 20, No. 7-8, e3041

Stieglitz, Marc S.; Fenske, Stefanie; Hammelmann, Verena; Becirovic, Elvir; Schöttle, Verena; Delorme, James E.; Schöll-Weidinger, Martha; Mader, Robert; Deussing, Jan; Wolfer, David P.; Seeliger, Mathias W.; Albrecht, Urs; Wotjak, Carsten T.; Biel, Martin; Michalakis, Stylianos; Wahl-Schott, Christian (2018): Disturbed Processing of Contextual Information in HCN3 Channel Deficient Mice. In: Frontiers in Molecular Neuroscience, Vol. 10, 436

Svilenov, Hristo ORCID: 0000-0001-5863-9569; Gentiluomo, Lorenzo; Friess, Wolfgang; Roessner, Dierk; Winter, Gerhard (December 2018): A New Approach to Study the Physical Stability of Monoclonal Antibody Formulations Dilution From a Denaturant. In: Journal of Pharmaceutical Sciences, Vol. 107, No. 12: pp. 3007-3013 [PDF, 1MB]

Svilenov, Hristo ORCID: 0000-0001-5863-9569; Markoja, Uros; Winter, Gerhard (April 2018): Isothermal chemical denaturation as a complementary tool to overcome limitations of thermal differential scanning fluorimetry in predicting physical stability of protein formulations. In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 125: pp. 106-113 [PDF, 1MB]

Thauvin, Cedric; Schwarz, Bettina; Delie, Florence; Allemann, Eric (2018): Functionalized PLA polymers to control loading and/or release properties of drug-loaded nanoparticles. In: International Journal of Pharmaceutics, Vol. 548, No. 2: pp. 771-777

Toth, Krisztian; Höfner, Georg; Wanner, Klaus T. (2018): Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with a trans-alkene spacer as potent GABA uptake inhibitors. In: Bioorganic & Medicinal Chemistry, Vol. 26, No. 22: pp. 5944-5961

Toth, Krisztian; Höfner, Georg; Wanner, Klaus T. (2018): Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with an alkyne spacer as GABA uptake inhibitors. In: Bioorganic & Medicinal Chemistry, Vol. 26, No. 12: pp. 3668-3687

Urushibara, Ko; Ferrand, Yann; Liu, Zhiwei; Masu, Hyuma; Pophristic, Vojislava; Tanatani, Aya; Huc, Ivan (2018): Frustrated Helicity: Joining the Diverging Ends of a Stable Aromatic Amide Helix to Form a Fluxional Macrocycle. In: Angewandte Chemie-International Edition, Vol. 57, No. 26: pp. 7888-7892

Vallade, Maelle; Reddy, Post Sai; Fischer, Lucile; Huc, Ivan (2018): Enhancing Aromatic Foldamer Helix Dynamics to Probe Interactions with Protein Surfaces. In: European Journal of Organic Chemistry, No. 40: pp. 5489-5498

Vedove, Elena Dalle; Costabile, Gabriella; Merkel, Olivia M. (2018): Mannose and Mannose-6-Phosphate Receptor-Targeted Drug Delivery Systems and Their Application in Cancer Therapy. In: Advanced Healthcare Materials, Vol. 7, No. 14, 1701398

Vlugt, Lucien E. P. M. van der; Eger, Katrien; Müller, Christoph; Ninaber, Dennis K.; Zarcone, Maria C.; Amatngalim, Gimano D.; Bracher, Franz; Mutius, Erika von; Smits, Hermelijn H.; Hiemstra, Pieter S. (2018): Farm dust reduces viral load in human bronchial epithelial cells by increasing barrier function and antiviral responses. In: Journal of Allergy and Clinical Immunology, Vol. 141, No. 5: pp. 1949-1952

Voegerl, Katharina; Ong, Duc Nghia; Bracher, Franz (2018): Reductive N-Arylethylation of Aromatic Amines and N-Heterocycles with Enol Ethers. In: Synthesis-Stuttgart, Vol. 50, No. 6: pp. 1323-1330

Vollrath, Ilona; Friess, Wolfgang; Freitag, Angelika; Hawe, Andrea; Winter, Gerhard (2018): Does controlled nucleation impact the properties and stability of lyophilized monoclonal antibody formulations? In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 129: pp. 134-144

Vollrath, Moritz; Engert, Julia; Winter, Gerhard (2018): New insights into process understanding of solid lipid extrusion (SLE) of extruded lipid implants for sustained protein delivery. In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 130: pp. 11-21

Wang, Bifeng; Friess, Wolfgang (2018): Lipid-coated mannitol core microparticles for sustained release of protein. In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 128: pp. 91-97

Wang, Ji; Wang, Jing; Zhang, Kai; Wang, Yanfang; Bao, Xuanwen (2018): Bayesian Network Meta-Analysis of the Effectiveness of Various Interventions for Nontraumatic Osteonecrosis of the Femoral Head. In: Biomed Research International, 2790163

Wein, Thomas; Höfner, Georg; Rappenglück, Sebastian; Sichler, Sonja; Niessen, Karin V.; Seeger, Thomas; Worek, Franz; Thiermann, Horst; Wanner, Klaus T. (2018): Searching for putative binding sites of the bispyridinium compound MB327 in the nicotinic acetylcholine receptor. In: Toxicology Letters, Vol. 293: pp. 184-189

Werner, Benjamin Patrick; Winter, Gerhard (2018): Expanding Bedside Filtration-A Powerful Tool to Protect Patients From Protein Aggregates. In: Journal of Pharmaceutical Sciences, Vol. 107, No. 11: pp. 2775-2788

West, Lorna Marie; Vetter-Kerkhoff, Cornelia; Miljkovic, Nenad; Frontini, Roberto (2018): Is there a need for a hospital pharmacy common training framework? Review of the literature on the impact of educational interventions on health outcome. In: European Journal of Hospital Pharmacy-Science and Practice, Vol. 25, No. 1: pp. 6-9

Yordanova, Yordanka; Vanderlinden, Willem; Stoll, Raphael; Rüdiger, Daniel; Tosstorff, Andreas; Zaremba, Wolfgang; Winter, Gerhard; Zahler, Stefan; Friess, Wolfgang (2018): Zn2+-triggered self-assembly of Gonadorelin [6-D-Phe] to produce nanostructures and fibrils. In: Scientific Reports, Vol. 8, 11280

Zhang, Xiaohan; Chytil, Petr; Etrych, Tomas; Liu, Weiwei; Rodrigues, Leticia; Winter, Gerhard; Filippov, Sergey K.; Papadakis, Christine M. (2018): Binding of HSA to Macromolecular rho HPMA Based Nanoparticles for Drug Delivery: An Investigation Using Fluorescence Methods. In: Langmuir, Vol. 34, No. 27: pp. 7998-8006

Ziach, Krzysztof; Chollet, Celine; Parissi, Vincent; Prabhakaran, Panchami; Marchivie, Mathieu; Corvaglia, Valentina; Bose, Partha Pratim; Laxmi-Reddy, Katta; Godde, Frederic; Schmitter, Jean-Marie; Chaignepain, Stephane; Pourquier, Philippe; Huc, Ivan (2018): Single helically folded aromatic oligoamides that mimic the charge surface of double-stranded B-DNA. In: Nature Chemistry, Vol. 10, No. 5: pp. 511-518

2017

Agostini, Elisa; Winter, Gerhard; Engert, Julia (2017): Scale-up of water-based spider silk film casting using a film applicator. In: International Journal of Pharmaceutics, Vol. 532, No. 1: pp. 13-20

Arlt, E.; Arndt, L.; Breit, A.; Wennemuth, G.; Biel, M.; Wahl, C.; Gudermann, T.; Klugbauer, N.; Boekhoff, I. (2017): Two-pore channel protein 1 contributes to NAADP triggered acrosome reaction in spermatozoa. In: Reproduction in Domestic Animals, Vol. 52: pp. 6-7

Balsevich, Georgia; Häusl, Alexander S.; Meyer, Carola W.; Karamihalev, Stoyo; Feng, Xixi; Poehlmann, Max L.; Dournes, Carine; Uribe-Marino, Andres; Santarelli, Sara; Labermaier, Christiana; Hafner, Kathrin; Mao, Tianqi; Breitsamer, Michaela; Theodoropoulou, Marily; Namendorf, Christian; Uhr, Manfred; Paez-Pereda, Marcelo; Winter, Gerhard; Hausch, Felix; Chen, Alon; Tschöp, Matthias H.; Rein, Theo; Gassen, Nils C.; Schmidt, Mathias V. (2017): Stress-responsive FKBP51 regulates AKT2-AS160 signaling and metabolic function. In: Nature Communications, Vol. 8, 1725

Bartel, Karin; Winzi, Maria; Ulrich, Melanie; Koeberle, Andreas; Menche, Dirk; Werz, Oliver; Müller, Rolf; Guck, Jochen; Vollmar, Angelika M.; Schwarzenberg, Karin von (2017): V-ATPase inhibition increases cancer cell stiffness and blocks membrane related Ras signaling - a new option for HCC therapy. In: Oncotarget, Vol. 8, No. 6: pp. 9476-9487

Biel, M. (2017): Endolysosomal two-pore channels: from genes to function. In: Acta Physiologica, Vol. 221: p. 8

Bobak, Nicole; Feliciangeli, Sylvain; Chen, Cheng-Chang; Ben Soussia, Ismail; Bittner, Stefan; Pagnotta, Sophie; Ruck, Tobias; Biel, Martin; Wahl-Schott, Christian; Grimm, Christian; Meuth, Sven G.; Lesage, Florian (2017): Recombinant tandem of pore-domains in a Weakly Inward rectifying K+ channel 2 (TWIK2) forms active lysosomal channels. In: Scientific Reports, Vol. 7, 649

Bracher, Franz; Tremmel, Tim (2017): From Lead to Drug Utilizing a Mannich Reaction: The Topotecan Story. In: Archiv der Pharmazie, Vol. 350, No. 7, e1600236

Bracher, Franz; Tremmel, Tim (2017): The Chemistry of the Canthin-4-ones. In: Mini-Reviews in Organic Chemistry, Vol. 14, No. 2: pp. 92-98

Breitsamer, Michaela; Winter, Gerhard (2017): Needle-Free Injection of Vesicular Phospholipid Gels-A Novel Approach to Overcome an Administration Hurdle for Semisolid Depot Systems. In: Journal of Pharmaceutical Sciences, Vol. 106, No. 4: pp. 968-972

Butler, Michael R.; Ma, Hongwei; Yang, Fan; Belcher, Joshua; Le, Yun-Zheng; Mikoshiba, Katsuhiko; Biel, Martin; Michalakis, Stylianos; Iuso, Anthony; Krizaj, David; Ding, Xi-Qin (2017): Endoplasmic reticulum (ER) Ca2+-channel activity contributes to ER stress and cone death in cyclic nucleotide-gated channel deficiency. In: Journal of Biological Chemistry, Vol. 292, No. 27: pp. 11189-11205

Böhm, Sybille; Riedmayr, Lisa M.; Nguyen, O. N. Phuong; Giessl, Andreas; Liebscher, Toni; Butz, Elisabeth S.; Schön, Christian; Michalakis, Stylianos; Wahl-Schott, Christian; Biel, Martin; Becirovic, Elvir (2017): Peripherin-2 and Rom-1 have opposing effects on rod outer segment targeting of retinitis pigmentosa-linked peripherin-2 mutants. In: Scientific Reports, Vol. 7, 2321

Castonguay, Jan; Orth, Joachim H. C.; Müller, Thomas; Sleman, Faten; Grimm, Christian; Wahl-Schott, Christian; Biel, Martin; Mallmann, Robert Theodor; Bildl, Wolfgang; Schulte, Uwe; Klugbauer, Norbert (2017): The two-pore channel TPC1 is required for efficient protein processing through early and recycling endosomes. In: Scientific Reports, Vol. 7, 10038

Chao, Yu-Kai; Schludi, Verena; Chen, Cheng-Chang; Butz, Elisabeth; Nguyen, O. N. Phuong; Müller, Martin; Krüger, Jens; Kammerbauer, Claudia; Ben-Johny, Manu; Vollmar, Angelika M.; Berking, Carola; Biel, Martin; Wahl-Schott, Christian A.; Grimm, Christian (2017): TPC2 polymorphisms associated with a hair pigmentation phenotype in humans result in gain of channel function by independent mechanisms. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, No. 41, E8595-E8602

Chen, Cheng-Chang; Butz, Elisabeth S.; Chao, Yu-Kai; Grishchuk, Yulia; Becker, Lars; Heller, Stefan; Slaugenhaupt, Susan A.; Biel, Martin; Wahl-Schott, Christian; Grimm, Christian (2017): Small Molecules for Early Endosome-Specific Patch Clamping. In: Cell Chemical Biology, Vol. 24, No. 7: pp. 907-916

Chen, Cheng-Chang; Cang, Chunlei; Fenske, Stefanie; Butz, Elisabeth; Chao, Yu-Kai; Biel, Martin; Ren, Dejian; Wahl-Schott, Christian; Grimm, Christian (2017): Patch-clamp technique to characterize ion channels in enlarged individual endolysosomes. In: Nature Protocols, Vol. 12, No. 8: pp. 1639-1658

Decembrini, Sarah; Martin, Catherine; Sennlaub, Florian; Chemtob, Sylvain; Bie, Martin; Samardzija, Marijana; Moulin, Alexandre; Behar-Cohen, Francine; Arsenijevic, Yvan (2017): Cone Genesis Tracing by the Chrnb4-EGFP Mouse Line: Evidences of Cellular Material Fusion after Cone Precursor Transplantation. In: Molecular therapy, Vol. 25, No. 3: pp. 634-653

Deglmann, Claus J.; Błażków-Schmalzbauer, Katarzyna; Moorkamp, Sarah; Susha, Andrei S.; Herrler, Tanja; Giunta, Riccardo E.; Wagner, Ernst; Rogach, Andrey L.; Baumeister, Ruediger G.; Ogris, Manfred (2017): Cadmium Telluride Quantum Dots as a Fluorescence Marker for Adipose Tissue Grafts. In: Annals of Plastic Surgery, Vol. 78, No. 2: pp. 217-222 [PDF, 586kB]

Ellwart, Mario; Höfner, Georg; Gerwien, Aaron; Wanner, Klaus T.; Knochel, Paul (2017): Synthesis and Bioactivity of Novel N-Benzylic and N-Phenethylic Ephedrine Derivatives. In: Synthesis-Stuttgart, Vol. 49, No. 23: pp. 5159-5166

Even, Marie-Paule; Bobbala, Sharan; Gibson, Blake; Hook, Sarah; Winter, Gerhard; Engert, Julia (2017): Twin-screw extruded lipid implants containing TRP2 peptide for tumour therapy. In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 114: pp. 79-87

Fanter, Lena; Müller, Christoph; Schepmann, Dirk; Bracher, Franz; Wünsch, Bernhard (2017): Chiral-pool synthesis of 1,2,4-trisubstituted 1,4-diazepanes as novel sigma(1) receptor ligands. In: Bioorganic & Medicinal Chemistry, Vol. 25, No. 17: pp. 4778-4799

Farias Vercoza, Brunno Renato; Prado Godinho, Joseane Lima; Teixeira de Macedo-Silva, Sara; Huber, Kilian; Bracher, Franz; Souza, Wanderley de; Fernandes Rodrigues, Juliany Cola (2017): KH-TFMDI, a novel sirtuin inhibitor, alters the cytoskeleton and mitochondrial metabolism promoting cell death in Leishmania amazonensis. In: Apoptosis, Vol. 22, No. 9: pp. 1169-1188

Feldmann, Daniel P.; Xie, Yuran; Jones, Steven K.; Yu, Dongyue; Moszczynska, Anna; Merkel, Olivia M. (2017): The impact of microfluidic mixing of triblock micelleplexes on in vitro/in vivo gene silencing and intracellular trafficking. In: Nanotechnology, Vol. 28, No. 22, 224001

Fuchs, Simone; Bischoff, Iris; Willer, Elisabeth A.; Bräutigam, Jacqueline; Bubik, Martin F.; Erdelmeier, Clemens A. J.; Koch, Egon; Faleschini, Maria T.; Mieri, Maria de; Bauhart, Milena; Zahler, Stefan; Hensel, Andreas; Hamburger, Matthias; Potterat, Olivier; Fürst, Robert (2017): The Dual Edema-Preventing Molecular Mechanism of the Crataegus Extract WS 1442 Can Be Assigned to Distinct Phytochemical Fractions. In: Planta Medica, Vol. 83, No. 8: pp. 701-709

Grimm, Christian; Butz, Elisabeth; Chen, Cheng-Chang; Wahl-Schott, Christian; Biel, Martin (2017): From mucolipidosis type IV to Ebola: TRPML and two-pore channels at the crossroads of endo-lysosomal trafficking and disease. In: Cell Calcium, Vol. 67: pp. 148-155

Grimm, Christian; Chen, Cheng-Chang; Wahl-Schott, Christian; Biel, Martin (February 2017): Two-Pore Channels: Catalyzers of Endolysosomal Transport and Function. In: Frontiers in pharmacology, Vol. 8, 45 [PDF, 662kB]

Hall, Arnaldur; Lächelt, Ulrich; Bartek, Jiri; Wagner, Ernst; Moghimi, Seyed Moein (2017): Polyplex Evolution: Understanding Biology, Optimizing Performance. In: Molecular therapy, Vol. 25, No. 7: pp. 1476-1490

Hammink, Roel; Eggermont, Loek J.; Zisis, Themistoklis; Tel, Jurjen; Figdor, Carl G.; Rowan, Alan E.; Blank, Kerstin G. (2017): Affinity-Based Purification of Polyisocyanopeptide Bioconjugates. In: Bioconjugate Chemistry, Vol. 28, No. 10: pp. 2560-2568

Hauke, Tobias J.; Herzig, Volker (2017): Dangerous arachnids-Fake news or reality? In: Toxicon, Vol. 138: pp. 173-183

Heissig, Philipp; Schrimpf, Waldemar; Hadwiger, Philipp; Wagner, Ernst; Lamb, Don C. (2017): Monitoring integrity and localization of modified single-stranded RNA oligonucleotides using ultrasensitive fluorescence methods.
In: PLOS One 12(3), e0173401

Heller, Philipp; Hobernik, Dominika; Lächelt, Ulrich; Schinnerer, Meike; Weber, Benjamin; Schmidt, Manfred; Wagner, Ernst; Bros, Matthias; Barz, Matthias (2017): Combining reactive triblock copolymers with functional cross-linkers: A versatile pathway to disulfide stabilized-polyplex libraries and their application as pDNA vaccines. In: Journal of Controlled Release, Vol. 258: pp. 146-160

Herms, Jochen; Schön, Christian (2017): In vivo imaging of retinal neurodegeneration at the single cell level in humans. In: Brain, Vol. 140: pp. 1542-1543

Herrmann, Stefan; Rajab, Hamsa; Christ, Irina; Schirdewahn, Christoph; Höfler, Daniel; Fischer, Michael J. M.; Bruno, Ariane; Fenske, Stefanie; Gruner, Christian; Kramer, Felix; Wachsmann, Tassilo; Wahl-Schott, Christian; Stieber, Juliane; Biel, Martin; Ludwig, Andreas (2017): Protein kinase A regulates inflammatory pain sensitization by modulating HCN2 channel activity in nociceptive sensory neurons. In: Pain, Vol. 158, No. 10: pp. 2012-2024

Jena, Sampreeti; Horn, Jacqueline; Suryanarayanan, Raj; Friess, Wolfgang; Aksan, Alptekin (2017): Effects of Excipient Interactions on the State of the Freeze-Concentrate and Protein Stability. In: Pharmaceutical Research, Vol. 34, No. 2: pp. 462-478

Jones, Steven K.; Sarkar, Anwesha; Feldmann, Daniel P.; Hoffmann, Peter; Merkel, Olivia M. (2017): Revisiting the value of competition assays in folate receptor-mediated drug delivery. In: Biomaterials, Vol. 138: pp. 35-45

Khan, Arif O.; Becirovic, Elvir; Betz, Christian; Neuhaus, Christine; Altmüller, Janine; Riedmayr, Lisa Maria; Motameny, Susanne; Nürnberg, Gudrun; Nürnberg, Peter; Bolz, Hanno J. (2017): A deep intronic CLRN1 (USH3A) founder mutation generates an aberrant exon and underlies severe Usher syndrome on the Arabian Peninsula. In: Scientific Reports, Vol. 7, 1411

Klein, Philipp M.; Reinhard, Sören; Zhang, Wei; Klinker, Kristina; Kern, Sarah; Kessel, Eva; Barz, Matthias; Wagner, Ernst (2017): Novel Poly(Sarcosine) Click Shielding Agents Improve Circulation of Redox-Sensitive siRNA Lipo-Polyplexes In Vivo. In: Molecular therapy, Vol. 25, No. 5: p. 144

Knappmann, Inga; Lehmkuhl, Kirstin; Köhler, Jens; Schepmann, Dirk; Giera, Martin; Bracher, Franz; Wünsch, Bernhard (2017): Lipase-catalyzed kinetic resolution as key step in the synthesis of enantiomerically pure a ligands with 2-benzopyran structure. In: Bioorganic & Medicinal Chemistry, Vol. 25, No. 13: pp. 3384-3395

Koch, Susanne F.; Duong, Jimmy K.; Hsu, Chun-Wei; Tsai, Yi-Ting; Lin, Chyuan-Sheng; Wahl-Schott, Christian A.; Tsang, Stephen H. (2017): Genetic rescue models refute nonautonomous rod cell death in retinitis pigmentosa. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, No. 20: pp. 5259-5264

Koczian, F.; Vomacka, J.; Vick, B.; Hettich, B.; Kazmaier, U.; Sieber, S.; Jeremias, I.; Vollmar, A.; Braig, S. (2017): Targeting the ER-Mitochondrial Interface of Cell Death Sensitizes Leukemia Cells towards Cytostatics. In: Annals of Hematology, Vol. 96: S73-S73

Korpus, Christoph; Friess, Wolfgang (2017): Evaluation of Different Holder Devices for Freeze-Drying in Dual-Chamber Cartridges With a Focus on Energy Transfer. In: Journal of Pharmaceutical Sciences, Vol. 106, No. 4: pp. 1092-1101

Korpus, Christoph; Friess, Wolfgang (2017): Lyophilization Cycle Design for Dual Chamber Cartridges and a Method for Online Process Control: The "DCC LyoMate" Procedure. In: Journal of Pharmaceutical Sciences, Vol. 106, No. 8: pp. 2077-2087

Krauss, Jürgen; Stadler, Martina; Bracher, Franz (2017): Synthesis and Structure-Activity Relationships of Novel Benzylamine-Type Antifungals as Butenafine-Related Antimycotics. In: Archiv der Pharmazie, Vol. 350, No. 5, e1600342

Kreitmeyr, Katharina; Both, Ulrich von; Pecar, Alenka; Borde, Johannes P.; Mikolajczyk, Rafael; Hübner, Johannes (2017): Pediatric antibiotic stewardship: successful interventions to reduce broad-spectrum antibiotic use on general pediatric wards. In: Infection, Vol. 45, No. 4: pp. 493-504

Köpf, Ellen; Schröder, Rudolf; Brezesinski, Gerald; Friess, Wolfgang (2017): The film tells the story: Physical-chemical characteristics of IgG at the liquid-air interface. In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 119: pp. 396-407

Lacaille-Dubois, Marie-Aleth; Wagner, Hildebert (2017): New perspectives for natural triterpene glycosides as potential adjuvants. In: Phytomedicine, Vol. 37: pp. 49-57

Lamouroux, Arthur; Sebaoun, Laure; Wicher, Barbara; Kauffmann, Brice; Ferrand, Yann; Maurizot, Victor; Huc, Ivan (2017): Controlling Dipole Orientation through Curvature: Aromatic Foldamer Bent beta-Sheets and Helix-Sheet-Helix Architectures. In: Journal of the American Chemical Society, Vol. 139, No. 41: pp. 14668-14675

Laprell, Laura; Tochitsky, Ivan; Kaur, Kuldeep; Manookin, Michael B.; Stein, Marco; Barber, David M.; Schön, Christian; Michalakis, Stylianos; Biel, Martin; Kramer, Richard H.; Sumser, Martin P.; Trauner, Dirk; Gelder, Russell N. van (2017): Photopharmacological control of bipolar cells restores visual function in blind mice. In: Journal of Clinical investigation, Vol. 127, No. 7: pp. 2598-2611

Lee, Dian-Jang; Kessel, Eva; Lehto, Taavi; Liu, Xueying; Yoshinaga, Naoto; Padari, Kart; Chen, Ying-Chen; Kempter, Susanne; Uchida, Satoshi; Rädler, Joachim O.; Pooga, Margus; Sheu, Ming-Thau; Kataoka, Kazunori; Wagner, Ernst (2017): Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability for In Vivo Gene Silencing in Leukemia. In: Bioconjugate Chemistry, Vol. 28, No. 9: pp. 2393-2409

Levacic, Ana Krhac; Morys, Stephan; Kempter, Susanne; Lächelt, Ulrich; Wagner, Ernst (2017): Minicircle Versus Plasmid DNA Delivery by Receptor-Targeted Polyplexes. In: Human Gene therapy, Vol. 28, No. 10: pp. 862-874

Liu, Xiaowen; Zhang, Peng; Rodl, Wolfgang; Maier, Kevin; Lächelt, Ulrich; Wagner, Ernst (2017): Toward Artificial Immunotoxins: Traceless Reversible Conjugation of RNase A with Receptor Targeting and Endosomal Escape Domains. In: Molecular Pharmaceutics, Vol. 14, No. 5: pp. 1439-1449

Lutz, Toni; Wein, Thomas; Höfner, Georg; Wanner, Klaus T. (2017): Development of Highly Potent GAT1 Inhibitors: Synthesis of Nipecotic Acid Derivatives with N-Arylalkynyl Substituents. In: ChemMedChem, Vol. 12, No. 5: pp. 362-371

Mailaender-Sanchez, Daniela; Braunsdorf, Christina; Grumaz, Christian; Müller, Christoph; Lorenz, Stefan; Stevens, Philip; Wagener, Jeanette; Hebecker, Betty; Hube, Bernhard; Bracher, Franz; Sohn, Kai; Schaller, Martin (2017): Antifungal defense of probiotic Lactobacillus rhamnosus GG is mediated by blocking adhesion and nutrient depletion.
In: PLOS One 12(10), e0184438

Mandl, Melanie M.; Zhang, Siwei; Ulrich, Melanie; Schmöckel, Elisa; Mayr, Doris; Vollmar, Angelika M.; Liebl, Johanna (2017): Inhibition of Cdk5 induces cell death of tumor-initiating cells. In: British Journal of Cancer, Vol. 116, No. 7: pp. 912-922

Martos, Ariadna; Koch, Wendelin; Jiskoot, Wim; Wuchner, Klaus; Winter, Gerhard; Friess, Wolfgang; Hawe, Andrea (2017): Trends on Analytical Characterization of Polysorbates and Their Degradation Products in Biopharmaceutical Formulations. In: Journal of Pharmaceutical Sciences, Vol. 106, No. 7: pp. 1722-1735

Meier, Christopher; Steinhauer, Tamara N.; Koczian, Fabian; Plitzko, Birte; Jarolim, Katharina; Girreser, Ulrich; Braig, Simone; Marko, Doris; Vollmar, Angelika M.; Clement, Bernd (2017): A Dual Topoisomerase Inhibitor of Intense Pro-Apoptotic and Antileukemic Nature for Cancer Treatment. In: ChemMedChem, Vol. 12, No. 5: pp. 347-352

Meier, Christopher; Steinhauer, Tamara N.; Koczian, Fabian; Plitzko, Birte; Jarolim, Katharina; Girreser, Ulrich; Braig, Simone; Marko, Doris; Vollmar, Angelika M.; Clement, Bernd (2017): Cover Picture: A Dual Topoisomerase Inhibitor of Intense Pro-Apoptotic and Antileukemic Nature for Cancer Treatment (ChemMedChem 5/2017). In: ChemMedChem, Vol. 12, No. 5: p. 346

Melzer, Benedikt C.; Bracher, Franz (2017): A novel approach to oxoisoaporphine alkaloids via regioselective metalation of alkoxy isoquinolines. In: Beilstein Journal of Organic Chemistry, Vol. 13: pp. 1564-1571

Michalakis, Stylianos; Fischer, M. Dominik; Schön, Christian; Wilhelm, Barbara; Zobor, Ditta; Muhlfriedel, Regine; Sothilingam, Vithiyanjali; Kohl, Susanne; Peters, Tobias; Zrenner, Eberhart; Bartz-Schmidt, Karl Ulrich; Üffing, Marius; Wissinger, Bernd; Seeliger, Mathias; Biel, Martin (2017): Gene Supplementation Therapy for CNGA3-Linked Achromatopsia. In: Molecular therapy, Vol. 25, No. 5: p. 354

Michalakis, Stylianos; Schön, Christian; Becirovic, Elvir; Biel, Martin (2017): Gene therapy for achromatopsia. In: Journal of Gene Medicine, Vol. 19, No. 3, e2944

Michalakis, Stylianos; Shaltiel, Lior; Sothilingam, Vithiyanjali; Koch, Susanne; Schludi, Verena; Krause, Stefanie; Zeitz, Christina; Audo, Isabelle; Lancelot, Marie-Elise; Hamel, Christian; Meunier, Isabelle; Preising, Markus N.; Friedburg, Christoph; Lorenz, Birgit; Zabouri, Nawal; Haverkamp, Silke; Garcia Garrido, Marina; Tanimoto, Naoyuki; Seeliger, Mathias W.; Biel, Martin; Wahl-Schott, Christian A. (2017): Mosaic synaptopathy and functional defects in Cav1.4 heterozygous mice and human carriers of CSNB2 (vol 23, pg 1538, 2014). In: Human Molecular Genetics, Vol. 26, No. 2: p. 466

Misslinger, Matthias; Gsaller, Fabio; Hortschansky, Peter; Müller, Christoph; Bracher, Franz; Bromley, Michael J.; Haas, Hubertus (2017): The cytochrome b(5) CybE is regulated by iron availability and is crucial for azole resistance in A. fumigatus. In: Metallomics, Vol. 9, No. 11: pp. 1655-1665

Moghimi, S. Moein; Wagner, Ernst (2017): Nanoparticle Technology: Having Impact, but Needing Further Optimization. In: Molecular therapy, Vol. 25, No. 7: pp. 1461-1463

Moser, Christina; Rüdiger, Daniel; Foerster, Florian; Blume, Julia von; Yu, Peng; Kuster, Bernhard; Kazmaier, Uli; Vollmar, Angelika M.; Zahler, Stefan (2017): Persistent inhibition of pore-based cell migration by sub-toxic doses of miuraenamide, an actin filament stabilizer. In: Scientific Reports, Vol. 7, 16407

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Müller, Christoph; Hemmers, Sandra; Bartl, Nicholas; Plodek, Alois; Körner, Andreas; Mirakaj, Valbona; Giera, Martin; Bracher, Franz (2017): New chemotype of selective and potent inhibitors of human delta 24-dehydrocholesterol reductase. In: European Journal of Medicinal Chemistry, Vol. 140: pp. 305-320

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Neiens, Patrick; Höfner, Georg; Wanner, Klaus T. (2017): Determination of the enantiomeric purity of the selective dopamine transporter inhibitor (+)-R,R-4-(2-benzhydryloxyethyl)-1-(4-fluorobenzyl)piperidin-3-ol. In: Chirality, Vol. 29, No. 6: pp. 294-303

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Nino-Pariente, Amaya; Arminan, Ana; Reinhard, Sören; Scholz, Claudia; Kos, Petra; Wagner, Ernst; Vicent, Maria J. (2017): Design of Poly-l-Glutamate-Based Complexes for pDNA Delivery (vol 10, 1700029, 2017). In: Macromolecular Bioscience, Vol. 17, No. 10, 1700245

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Occelli, Laurence M.; Schön, Christian; Seeliger, Mathias W.; Biel, Martin; Michalakis, Stylianos; Petersen-Jones, Simon M. (2017): Gene Supplementation Rescues Rod Function and Preserves Photoreceptor and Retinal Morphology in Dogs, Leading the Way Toward Treating Human PDE6A-Retinitis Pigmentosa. In: Human Gene therapy, Vol. 28, No. 12: pp. 1189-1201

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Rappenglück, Sebastian; Niessen, Karin V.; Seeger, Thomas; Worek, Franz; Thiermann, Horst; Wanner, Klaus T. (2017): Regioselective and Transition-Metal-Free Addition of tert-Butyl Magnesium Reagents to Pyridine Derivatives: A Convenient Method for the Synthesis of 3-Substituted 4-tert-Butylpyridine Derivatives. In: Synthesis-Stuttgart, Vol. 49, No. 17: pp. 4055-4064

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Reinhard, Sören; Wagner, Ernst (2017): How to Tackle the Challenge of siRNA Delivery with Sequence-Defined Oligoamino Amides. In: Macromolecular Bioscience, Vol. 17, No. 1, 1600152

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Schaarschmidt, Maren; Wanner, Klaus T. (2017): Synthesis of Allene Substituted Nipecotic Acids by Allenylation of Terminal Alkynes. In: Journal of Organic Chemistry, Vol. 82, No. 16: pp. 8371-8388

Schmidt, Simone K.; Höfner, Georg; Wanner, Klaus T. (2017): Determination of enantiomeric excess of nipecotic acid as 1-(7-nitrobenzo[c][1,2,5]oxadiazol-4-yl) derivatives. In: Chirality, Vol. 29, No. 1: pp. 48-56

Schmohl, Kathrin A.; Dolp, Patrick; Schug, Christina; Knoop, Kerstin; Klutz, Kathrin; Schwenk, Nathalie; Bartenstein, Peter; Nelson, Peter J.; Ogris, Manfred; Wagner, Ernst; Spitzweg, Christine (2017): Reintroducing the Sodium-Iodide Symporter to Anaplastic Thyroid Carcinoma. In: Thyroid, Vol. 27, No. 12: pp. 1534-1543

Schreiber, C.; Segerer, F. J.; Wagner, E.; Roidl, A.; Rädler, J. O. (2017): Characterizing single cell migration and transitions to different substrate coatings. In: European Biophysics Journal With Biophysics Letters, Vol. 46: S323-S323

Schuller, Marion; Höfner, Georg; Wanner, Klaus T. (2017): Simultaneous Multiple MS Binding Assays Addressing D-1 and D-2 Dopamine Receptors. In: ChemMedChem, Vol. 12, No. 19: pp. 1585-1594

Schuller, Marion; Riede, Kerstin; Gibbs-Seymour, Ian; Uth, Kristin; Sieg, Christian; Gehring, Andre P.; Ahel, Ivan; Bracher, Franz; Kessler, Benedikt M.; Elkins, Jonathan M.; Knapp, Stefan (2017): Discovery of a Selective Allosteric Inhibitor Targeting Macrodomain 2 of Polyadenosine-Diphosphate-Ribose Polymerase 14. In: ACS Chemical Biology, Vol. 12, No. 11: pp. 2866-2874

Schön, Christian; Sothilingam, Vithiyanjali; Mühlfriedel, Regine; Garrido, Marina Garcia; Beck, Susanne C.; Tanimoto, Naoyuki; Wissinger, Bernd; Paquet-Durand, Francois; Biel, Martin; Michalakis, Stylianos; Seeliger, Mathias W. (2017): Gene Therapy Successfully Delays Degeneration in a Mouse Model of PDE6A-Linked Retinitis Pigmentosa (RP43). In: Human Gene therapy, Vol. 28, No. 12: pp. 1180-1188

Sibbing, Dirk; Aradi, Daniel; Jacobshagen, Claudius; Gross, Lisa; Trenk, Dietmar; Geisler, Tobias; Orban, Martin; Gori, Tommaso; Hadamitzky, Martin; Merkely, Bela; Kiss, Robert Gabor; Komocsi, Andras; Dersi, Csaba A.; Thalmeier, Andreas; Loew, Anja; Holdt, Lesca; Teupser, Daniel; Ince, Hueseyin; Felix, Stephan B.; Parma, Radoslaw; Malek, Lukasz; Horstkotte, Jan; Bay-lacher, Monika; Schwinger, Robert; Rieber, Johannes; Mudra, Harald; Hausleiter, Jörg; Huber, Kurt; Neumann, Franz-Josef; Koltowski, Lukasz; Huczek, Zenon; Mehilli, Julinda; Massberg, Steffen (2017): A randomised trial on platelet function-guided de-escalation of antiplatelet treatment in ACS patients undergoing PCI Rationale and design of the Testing Responsiveness to Platelet Inhibition on Chronic Antiplatelet Treatment for Acute Coronary Syndromes (TROPICAL-ACS) Trial. In: Thrombosis and Haemostasis, Vol. 117, No. 1: pp. 188-195

Strüver, Kay; Friess, Wolfgang; Hedtrich, Sarah (2017): Development of a Perfusion Platform for Dynamic Cultivation of in vitro Skin Models. In: Skin Pharmacology and Physiology, Vol. 30, No. 4: pp. 180-189

Stöckelhuber, M.; Müller, C.; Vetter, F.; Mingo, V.; Lötters, S.; Wagner, N.; Bracher, F. (2017): Determination of Pesticides Adsorbed on Arthropods and Gastropods by a Micro-QuEChERS Approach and GC-MS/MS. In: Chromatographia, Vol. 80, No. 5: pp. 825-829

Trübenbach, Ines; Gorges, Jan; Kuhn, Jasmin; Kern, Sarah; Baratti, Emanuele; Kazmaier, Uli; Wagner, Ernst; Lächelt, Ulrich (2017): Sequence-Defined Oligoamide Drug Conjugates of Pretubulysin and Methotrexate for Folate Receptor Targeted Cancer Therapy. In: Macromolecular Bioscience, Vol. 17, No. 10, 1600520

Urnauer, Sarah; Klutz, Kathrin; Grünwald, Geoffrey K.; Morys, Stephan; Schwenk, Nathalie; Zach, Christian; Gildehaus, Franz-Josef; Rödl, Wolfgang; Ogris, Manfred; Wagner, Ernst; Spitzweg, Christine (2017): Systemic tumor-targeted sodium iodide symporter (NIS) gene therapy of hepatocellular carcinoma mediated by B6 peptide polyplexes. In: Journal of Gene Medicine, Vol. 19, No. 5, e2957

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Utzinger, Maximilian; Jarzebinska, Anita; Haag, Nicolas; Schweizer, Martin; Winter, Gerhard; Dohmen, Christian; Rudolph, Carsten; Plank, Christian (2017): cmRNA/lipoplex encapsulation in PLGA microspheres enables transfection via calcium phosphate cement (CPC)/PLGA composites. In: Journal of Controlled Release, Vol. 249: pp. 143-149

Vetter, F.; Müller, C.; Stöckelhuber, M.; Bracher, F. (2017): Determination of coumarin in seasonal bakery products using QuEChERS and GC-MS. In: Pharmazie, Vol. 72, No. 6: pp. 313-316

Vollrath, Ilona; Pauli, Victoria; Friess, Wolfgang; Freitag, Angelika; Hawe, Andrea; Winter, Gerhard (2017): Evaluation of Heat Flux Measurement as a New Process Analytical Technology Monitoring Tool in Freeze Drying. In: Journal of Pharmaceutical Sciences, Vol. 106, No. 5: pp. 1249-1257

Vollrath, Moritz; Engert, Julia; Winter, Gerhard (2017): Long-term release and stability of pharmaceutical proteins delivered from solid lipid implants. In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 117: pp. 244-255

Wagner, I.; Geh, K. J.; Hubert, M.; Winter, G.; Weber, K.; Classen, J.; Klinger, C.; Müller, R. S. (2017): Preliminary evaluation of cytosine-phosphate-guanine oligodeoxynucleotides bound to gelatine nanoparticles as immunotherapy for canine atopic dermatitis. In: Veterinary Record, Vol. 181, No. 5

Wagner, J. E.; Schön, C.; O'Riordan, C. R.; Scaria, A.; Cheng, S. H.; Biel, M.; Michalakis, S. (2017): Preclinical evaluation of rAAV.CNGB1 in the Cngb1 knockout mouse model of retinitis pigmentosa. In: Human Gene therapy, Vol. 28, No. 12: A78-A79

Wang, Bifeng; Friess, Wolfgang (2017): Spray drying of silica microparticles for sustained release application with a new sol-gel precursor. In: International Journal of Pharmaceutics, Vol. 532, No. 1: pp. 281-288

Wang, Shanshan; Li, Chengyi; Qian, Min; Jiang, Huiling; Shi, Wei; Chen, Jian; Lächelt, Ulrich; Wagner, Ernst; Lu, Weiyue; Wang, Yi; Huang, Rongqin (2017): Augmented glioma-targeted theranostics using multifunctional polymer-coated carbon nanodots. In: Biomaterials, Vol. 141: pp. 29-39

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Cattaneo, Giulia; Ubiali, Daniela; Calleri, Enrica; Rabuffetti, Marco; Höfner, Georg C.; Wanner, Klaus T.; Moraes, Marcela C. de; Martinelli, Leonardo K. B.; Santiago Santos, Diógenes; Speranza, Giovanna; Massolini, Gabriella (2016): Development, validation and application of a 96-well enzymatic assay based on LC-ESI-MS/MS quantification for the screening of selective inhibitors against Mycobacterium tuberculosis purine nucleoside phosphorylase. In: Analytica Chimica Acta, Vol. 943: pp. 89-97

Chen, Dong-Sheng; Wu, Yi-Quan; Zhang, Wei; Jiang, San-Jie; Chen, Shan-Ze (2016): Horizontal gene transfer events reshape the global landscape of arm race between viruses and homo sapiens. In: Scientific Reports, Vol. 6, 26934 [PDF, 1MB]

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Foerster, Florian; Chen, Tao; Altmann, Karl-Heinz; Vollmar, Angelika M. (2016): Actin-binding doliculide causes premature senescence in p53 wild type cells. In: Bioorganic & Medicinal Chemistry, Vol. 24, No. 2: pp. 123-129

Funke, Stefanie; Matilainen, Julia; Nalenz, Heiko; Bechtold-Peters, Karoline; Mahler, Hanns-Christian; Friess, Wolfgang (2016): Optimization of the bake-on siliconization of cartridges. Part I: Optimization of the spray-on parameters. In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 104: pp. 200-215

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He, Dongsheng; Müller, Katharina; Levacic, Ana Krhac; Kos, Petra; Lächelt, Ulrich; Wagner, Ernst (2016): Combinatorial Optimization of Sequence-Defined Oligo(ethanamino)amides for Folate Receptor-Targeted pDNA and siRNA Delivery. In: Bioconjugate Chemistry, Vol. 27, No. 3: pp. 647-659

Heissig, Philipp; Klein, Philipp M.; Hadwiger, Philipp; Wagner, Ernst (2016): DNA as Tunable Adaptor for siRNA Polyplex Stabilization and Functionalization. In: Molecular Therapy - Nucleic Acids, Vol. 5, e288 [PDF, 1MB]

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Hermawan, Adam; Wagner, Ernst; Roidl, Andreas (2016): Consecutive salinomycin treatment reduces doxorubicin resistance of breast tumor cells by diminishing drug efflux pump expression and activity. In: Oncology Reports, Vol. 35, No. 3: pp. 1732-1740

Herzog, Julia; Ehrlich, Sandra M.; Pfitzer, Lisa; Liebl, Johanna; Fröhlich, Thomas; Arnold, Georg J.; Mikulits, Wolfgang; Haider, Christine; Vollmar, Angelika M.; Zahler, Stefan (2016): Cyclin-dependent kinase 5 stabilizes hypoxia-inducible factor-1 alpha: a novel approach for inhibiting angiogenesis in hepatocellular carcinoma. In: Oncotarget, Vol. 7, No. 19: pp. 27108-27121

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Higel, Fabian; Seidl, Andreas; Sörgel, Fritz; Friess, Wolfgang (2016): N-glycosylation heterogeneity and the influence on structure, function and pharmacokinetics of monoclonal antibodies and Fc fusion proteins. In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 100: pp. 94-100

Hildebrandt, Christian; Mathaes, Roman; Saedler, Rainer; Winter, Gerhard (2016): Origin of Aggregate Formation in Antibody Crystal Suspensions Containing PEG. In: Journal of Pharmaceutical Sciences, Vol. 105, No. 3: pp. 1059-1065

Jiang, Qian; Yue, Dong; Nie, Yu; Xu, Xianghui; He, Yiyan; Zhang, Shiyong; Wagner, Ernst; Gu, Zhongwei (2016): Specially-Made Lipid-Based Assemblies for Improving Transmembrane Gene Delivery: Comparison of Basic Amino Acid Residue Rich Periphery. In: Molecular Pharmaceutics, Vol. 13, No. 6: pp. 1809-1821

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Kamlah, Alexandra; Lirk, Florian; Bracher, Franz (2016): A new approach to 1-substituted β-carbolines and isoquinolines utilizing tributyl[(Z)-2-ethoxyvinyl]stannane as a C-3,C-4 building block. In: Tetrahedron, Vol. 72, No. 6: pp. 837-845

Karimova, Madina; Splith, Victoria; Karpinski, Janet; Pisabarro, M. Teresa; Buchholz, Frank (2016): Discovery of Nigri/nox and Panto/pox site-specific recombinase systems facilitates advanced genome engineering. In: Scientific Reports, Vol. 6, 30130 [PDF, 1MB]

Keller, Marco; Wolfgardt, Annette; Müller, Christoph; Wilcken, Rainer; Böckler, Frank M.; Oliaro-Bosso, Simonetta; Ferrante, Terenzio; Balliano, Gianni; Bracher, Franz (2016): Arylpiperidines as a new class of oxidosqualene cyclase inhibitors. In: European Journal of Medicinal Chemistry, Vol. 109: pp. 13-22

Kerscher-Hack, Silke; Renukappa-Gutke, Thejavathi; Höfner, Georg; Wanner, Klaus T. (2016): Synthesis and biological evaluation of a series of N-alkylated imidazole alkanoic acids as mGAT3 selective GABA uptake inhibitors. In: European Journal of Medicinal Chemistry, Vol. 124: pp. 852-880

Kibat, Janek; Schirrmann, Thomas; Knape, Matthias J.; Helmsing, Saskia; Meier, Doris; Hust, Michael; Schröder, Christoph; Bertinetti, Daniela; Winter, Gerhard; Pardes, Khalid; Funk, Mia; Vala, Andrea; Giese, Nathalia; Herberg, Friedrich W.; Dübel, Stefan; Hoheisel, Jörg D. (2016): Utilisation of antibody microarrays for the selection of specific and informative antibodies from recombinant library binders of unknown quality. In: New Biotechnology, Vol. 33, No. 5: pp. 574-581

Kick, Kerstin; Nekolla, Katharina; Rehberg, Markus; Vollmar, Angelika M.; Zahler, Stefan (2016): New View on Endothelial Cell Migration Switching Modes of Migration Based on Matrix Composition. In: Arteriosclerosis thrombosis and Vascular Biology, Vol. 36, No. 12: pp. 2346-2357

Kilpatrick, Bethan S.; Yates, Elizabeth; Grimm, Christian; Schapira, Anthony H.; Patel, Sandip (2016): Endo-lysosomal TRP mucolipin-1 channels trigger global ER Ca2+ release and Ca2+ influx. In: Journal of Cell Science, Vol. 129, No. 20: pp. 3859-3867

Kirmeier, Thomas; Gopalakrishnan, Ranganath; Gormanns, Vanessa; Werner, Anna M.; Cuboni, Serena; Rudolf, Georg C.; Höfner, Georg; Wanner, Klaus T.; Sieber, Stephan A.; Schmidt, Ulrike; Holsboer, Florian; Rein, Theo; Hausch, Felix (2016): Azidobupramine, an Antidepressant-Derived Bifunctional Neurotransmitter Transporter Ligand Allowing Covalent Labeling and Attachment of Fluorophores.
In: PLOS ONE 11(2), e0148608 [PDF, 768kB]

Korpus, Christoph; Pikal, Michael; Friess, Wolfgang (2016): Heat Transfer Analysis of an Optimized, Flexible Holder System for Freeze-Drying in Dual Chamber Cartridges Using Different State-of-the-Art PAT Tools. In: Journal of Pharmaceutical Sciences, Vol. 105, No. 11: pp. 3304-3313

Kostic, Corinne; Crippa, Sylvain V.; Martin, Catherine; Kardon, Randy H.; Biel, Martin; Arsenijevic, Yvan; Kawasaki, Aki (2016): Determination of Rod and Cone Influence to the Early and Late Dynamic of the Pupillary Light Response. In: Investigative Ophthalmology & Visual Science, Vol. 57, No. 6: pp. 2501-2508

Köse, Meryem; Schiedel, Anke C.; Bauer, Alexander Andreas; Poschenrieder, Hermann; Burbiel, Joachim C.; Akkinepally, Raghuram Rao; Stachef, Hans-Dietrich; Müller, Christa E. (2016): Focused screening to identify new adenosine kinase inhibitors. In: Bioorganic & Medicinal Chemistry, Vol. 24, No. 21: pp. 5127-5133

Lee, Dian-Jang; He, Dongsheng; Kessel, Eva; Padari, Kärt; Kempter, Susanne; Lächelt, Ulrich; Rädler, Joachim O.; Pooga, Margus; Wagner, Ernst (2016): Tumoral gene silencing by receptor-targeted combinatorial siRNA polyplexes. In: Journal of Controlled Release, Vol. 244: pp. 280-291

Lee, Dian-Jang; Kessel, Eva; Edinger, Daniel; He, Dongsheng; Klein, Philipp M.; Voith von Voithenberg, Lena; Lamb, Don C.; Lächelt, Ulrich; Lehto, Taavi; Wagner, Ernst (2016): Dual antitumoral potency of EG5 siRNA nanoplexes armed with cytotoxic bifunctional glutamyl-methotrexate targeting ligand. In: Biomaterials, Vol. 77: pp. 98-110

Liebl, Johanna (2016): Cyclin dependent kinase 5-a novel target to enhance the antitumor immune response. In: Translational Cancer Research, Vol. 5: S587-S589

Liu, Xiaowen; Zhang, Peng; He, Dongsheng; Rödl, Wolfgang; Preiß, Tobias; Rädler, Joachim O.; Wagner, Ernst; Lächelt, Ulrich (2016): pH-Reversible Cationic RNase A Conjugates for Enhanced Cellular Delivery and Tumor Cell Killing. In: Biomacromolecules, Vol. 17, No. 1: pp. 173-182

Lutz, Toni A.; Spanner, Patrick; Wanner, Klaus T. (2016): A general approach to substituted diphenyldiazenes. In: Tetrahedron, Vol. 72, No. 12: pp. 1579-1589

Lächelt, Ulrich; Levacic, Ana Krhac; Wendel, Dominik; Wagner, Ernst (2016): Nonviral Gene Transfer by Sequence-Defined Proton-Sponges with Combined Nucleic Acid Binding and Endosomal Buffering: Balancing Basicities. In: Molecular therapy, Vol. 24: S195-S195

Merk, Henriette; Zhang, Siwei; Lehr, Thorsten; Müller, Christoph; Ulrich, Melanie; Bibb, James A.; Adams, Ralf H.; Bracher, Franz; Zahler, Stefan; Vollmar, Angelika M.; Liebl, Johanna (2016): Inhibition of endothelial Cdk5 reduces tumor growth by promoting non-productive angiogenesis. In: Oncotarget, Vol. 7, No. 5: pp. 6088-6104

Michalakis, Stylianos; Koch, Mirwa; Ma, Hongwei; Ding, Xi-Qin; Biel, Martin (2016): cGMP-cGKII signalling contributes to cone photoreceptor degeneration in achromatopsia. In: Investigative Ophthalmology & Visual Science, Vol. 57, No. 12

Mohammadi, Mariam; Li, Ying; Abebe, Daniel G.; Xie, Yuran; Kandil, Rima; Kraus, Teresa; Gomez-Lopez, Nardhy; Fujiwara, Tomoko; Merkel, Olivia M. (2016): Folate receptor targeted three-layered micelles and hydrogels for gene delivery to activated macrophages. In: Journal of Controlled Release, Vol. 244: pp. 269-279

Molokhia, Sarah; Burr, Randon M.; Flood, Maggie; Vallrath, Moritz; Winter, Gerhard; Ambati, Balamurali Krishna (2016): Lens Capsule Biodegradable Lipid Implant for Sustained-Release Anti-VEGF Therapy of Neovascular AMD. In: Investigative Ophthalmology & Visual Science, Vol. 57, No. 12

Mosion, Jan; Rauscher, Alexander; Willi, Taylor; Lang, Donna; Vertinsky, Talia; Vila-Rodriguez, Fidel; Kames, Christian; Panenka, William; Jarrett, Mike; Honer, William; Barr, Alasdair (2016): A Longitudinal Characterization of Cerebral Microbleeds in a Marginalized Population with High Rates of Mental Illness, Substance Abuse and Viral Infection. In: Neurology, Vol. 86

Movassaghian, Sara; Xie, Yuran; Hildebrandt, Claudia; Rosati, Rayna; Li, Ying; Kim, Na Hyung; Conti, Denise S.; Rocha, Sandro R. P. da; Yang, Zeng-Quan; Merkel, Olivia M. (2016): Post-Transcriptional Regulation of the GASC1 Oncogene with Active Tumor-Targeted siRNA-Nanoparticles. In: Molecular Pharmaceutics, Vol. 13, No. 8: pp. 2605-2621

Müller, Katharina; Klein, Philipp M.; Heissig, Philipp; Roidl, Andreas; Wagner, Ernst (2016): EGF receptor targeted lipo-oligocation polyplexes for antitumoral siRNA and miRNA delivery. In: Nanotechnology, Vol. 27, No. 46, 464001

Müller, Katherina; Kessel, Eva; Klein, Philipp M.; Höhn, Miriam; Wagner, Ernst (2016): Post-PEGylation of siRNA Lipo-oligoamino Amide Polyplexes Using Tetra-glutamylated Folic Acid as Ligand for Receptor-Targeted Delivery. In: Molecular Pharmaceutics, Vol. 13, No. 7: pp. 2332-2345

Nguyen, O. N. Phuong; Böhm, Sybille; Gießl, Andreas; Butz, Elisabeth S.; Wolfrum, Uwe; Brandstätter, Johann H.; Wahl-Schott, Christian; Biel, Martin; Becirovic, Elvir (2016): Peripherin-2 differentially interacts with cone opsins in outer segments of cone photoreceptors. In: Human Molecular Genetics, Vol. 25, No. 12: pp. 2367-2377

Niessen, K. V.; Muschik, S.; Langguth, F.; Rappenglück, S.; Seeger, T.; Thiermann, H.; Worek, F. (2016): Functional analysis of Torpedo californica nicotinic acetylcholine receptors in multiple activation states by SSM-based electrophysiology. In: Toxicology Letters, Vol. 247: pp. 1-10

Petrera, Marilena; Wein, Thomas; Allmendinger, Lars; Sindelar, Miriam; Pabel, Jörg; Höfner, Georg; Wanner, Klaus T. (2016): Development of Highly Potent GAT1 Inhibitors: Synthesis of Nipecotic Acid Derivatives by Suzuki-Miyaura Cross-Coupling Reactions. In: ChemMedChem, Vol. 11, No. 5: pp. 519-538

Pivodová, V.; Zahler, S.; Karas, D.; Valentová, K.; Ulrichova, J. (2016): In vitro study of 2,3-dehydrosilybin and its galloyl esters as potential inhibitors of angiogenesis. In: Pharmazie, Vol. 71, No. 8: pp. 478-483

Plodek, Alois; Bracher, Franz (2016): New Perspectives in the Chemistry of Marine Pyridoacridine Alkaloids. In: Marine Drugs, Vol. 14, No. 2, 26 [PDF, 6MB]

Podkowa, A.; Sałat, K.; Malikowska, N.; Kern, F.; Pabel, J.; Kulig, K.; Wanner, K. T.; Wojcieszak, E.; Furgala, A. (2016): Anticonvulsant activity of a novel gamma-aminobutyric acid transporter subtype 1 inhibitor in mice. In: European Neuropsychopharmacology, Vol. 26: S286-S286

Popp, Tobias A.; Tallant, Cynthia; Rogers, Catherine; Fedorov, Oleg; Brennan, Paul E.; Müller, Susanne; Knapp, Stefan; Bracher, Franz (2016): Development of Selective CBP/P300 Benzoxazepine Bromodomain Inhibitors. In: Journal of Medicinal Chemistry, Vol. 59, No. 19: pp. 8889-8912

Popp, Tobias Alexander; Uhl, Edgar; Ong, Duc Nghia; Dittrich, Sebastian; Bracher, Franz (2016): A new approach to monoprotected 1,4-benzodiazepines via a one-pot N-deprotection/reductive cyclization procedure. In: Tetrahedron, Vol. 72, No. 13: pp. 1668-1674

Reichel, Felix Friedrich; Peters, Tobias; Muehlfriedel, Regine; Biel, Martin; Paquet-Durand, Francois; Ueffing, Marius; Wissinger, Bernd; Bartz-Schmidt, Karl Ulrich; Fischer, M. Dominik; Michalakis, Stylianos (2016): Humoral immune response to subretinal AAV8 in non-human primates. In: Investigative Ophthalmology & Visual Science, Vol. 57, No. 12

Rodrigues, Leticia; Kyriakos, Konstantinos; Schneider, Fabian; Dietz, Hendrik; Winter, Gerhard; Papadakis, Christine M.; Hubert, Madlen (2016): Characterization of Lipid-Based Hexosomes as Versatile Vaccine Carriers. In: Molecular Pharmaceutics, Vol. 13, No. 11: pp. 3945-3954

Santos-Ferreira, Tiago; Völkner, Manuela; Borsch, Oliver; Haas, Jochen; Cimalla, Peter; Vasudevan, Praveen; Carmeliet, Peter; Corbeil, Denis; Michalakis, Stylianos; Koch, Edmund; Karl, Mike O.; Ader, Marius (2016): Author Response: Possibility of Cytoplasmic Transportation Between Donor-Host Cell Following Photoreceptor Transplantation. In: Investigative Ophthalmology & Visual Science, Vol. 57, No. 13: pp. 5336-5337

Scheffel, C.; Rappenglck, S.; Niessen, K.; Worek, F.; Thiermann, H.; Wanner, K.; Seeger, T. (2016): Electrophysiological drug-screening of bispyridinium-non-oxime-compounds on human nicotinic alpha 7 acetylcholine receptors - an alternative approach for the treatment of nerve agent poisoning -. In: Naunyn-Schmiedebergs Archives of Pharmacology, Vol. 389, No. 1: S42-S42

Schneider, Lina S.; Ulrich, Melanie; Lehr, Thorsten; Menche, Dirk; Müller, Rolf; Schwarzenberg, Karin von (2016): MDM2 antagonist nutlin-3a sensitizes tumors to V-ATPase inhibition. In: Molecular Oncology, Vol. 10, No. 7: pp. 1054-1062

Schuster, Simon L.; Segerer, Felix J.; Gegenfurtner, Florian A.; Kick, Kerstin; Schreiber, Christoph; Albert, Max; Vollmar, Angelika M.; Rädler, Joachim O.; Zahler, Stefan (2016): Contractility as a global regulator of cellular morphology, velocity, and directionality in low-adhesive fibrillary micro-environments. In: Biomaterials, Vol. 102: pp. 137-147

Schön, Christian; Asteriti, Sabrina; Koch, Susanne; Sothilingam, Vithiyanjali; Garrido, Marina Garcia; Tanimoto, Naoyuki; Herms, Jochen; Seeliger, Mathias W.; Cangiano, Lorenzo; Biel, Martin; Michalakis, Stylianos (2016): Loss of HCN1 enhances disease progression in mouse models of CNG channel-linked retinitis pigmentosa and achromatopsia. In: Human Molecular Genetics, Vol. 25, No. 6: pp. 1165-1175

Schön, Christian; Paquet-Durand, Francois; Michalakis, Stylianos (2016): Ca(v)1.4 L-Type Calcium Channels Contribute to Calpain Activation in Degenerating Photoreceptors of rd1 Mice.
In: PLOS ONE 11(6), e0156974 [PDF, 1MB]

Seitz, Immanuel Philipp; Fischer, M. Dominik; Michalakis, Stylianos; Wilhelm, Barbara; Kahle, Nadine; Zrenner, Eberhart; Ueffing, Marius; Bartz-Schmidt, Karl Ulrich; Biel, Martin; Wissinger, Bernd; Peters, Tobias (2016): rAAV8 biodistribution and shedding after subretinal injection in non-human primates. In: Investigative Ophthalmology & Visual Science, Vol. 57, No. 12

Sohail, Azmat; Jayaraman, Kumaresan; Venkatesan, Santhoshkannan; Gotfryd, Kamil; Daerr, Markus; Gether, Ulrik; Loland, Claus J.; Wanner, Klaus T.; Freissmuth, Michael; Sitte, Harald H.; Sandtner, Walter; Stockner, Thomas (2016): The Environment Shapes the Inner Vestibule of LeuT.
In: PLOS Computational Biology 12(11), e1005197 [PDF, 5MB]

Sothilingam, Vithiyanjali; Michalakis, Stylianos; Garrido, Marina Garcia; Biel, Martin; Tanimoto, Naoyuki; Seeliger, Mathias W. (2016): HCN1 Channels Enhance Rod System Responsivity in the Retina under Conditions of Light Exposure.
In: PLOS ONE 11(1), e0147728 [PDF, 1MB]

Tanimoto, Naoyuki; Michalakis, Stylianos; Weber, Bernhard H. F.; Wahl-Schott, Christian A.; Hammes, Hans-Peter; Seeliger, Mathias W. (2016): In-Depth Functional Diagnostics of Mouse Models by Single-Flash and Flicker Electroretinograms without Adapting Background Illumination. In: Retinal Degenerative Diseases: Mechanisms and Experimental therapy, Vol. 854: pp. 619-625

Tremmel, Tim; Puzik, Andreas; Gehring, André P.; Bracher, Franz (2016): Canthin-4-ones as Novel Antibacterial Agents. In: Archiv Der Pharmazie, Vol. 349, No. 9: pp. 710-723

Unzue, Andrea; Lafleur, Karine; Zhao, Hongtao; Zhou, Ting; Dong, Jing; Kolb, Peter; Liebl, Johanna; Zahler, Stefan; Caflisch, Amedeo; Nevado, Cristina (2016): Three stories on Eph kinase inhibitors: From in silico discovery to in vivo validation. In: European Journal of Medicinal Chemistry, Vol. 112: pp. 347-366

Wagner, Hildebert; Bauer, Rudolf; Melchart, Dieter (2016): New Analytical Monographs on TCM Herbal Drugs for Quality Proof. In: Forschende Komplementarmedizin, Vol. 23: pp. 16-20 [PDF, 219kB]

Wagner, I; Geh, K.; Winter, G.; Weber, K.; Mueller, R. S. (2016): Immunotherapy of canine atopic dermatitis with CpG oligodeoxynucleotides bound to gelatine nanoparticles. In: Allergy, Vol. 71: p. 69

Wein, Thomas; Petrera, Marilena; Allmendinger, Lars; Höfner, Georg; Pabel, Jörg; Wanner, Klaus T. (2016): Different Binding Modes of Small and Large Binders of GAT1. In: ChemMedChem, Vol. 11, No. 5: pp. 509-518

Westerhausen, Christoph; Schnitzler, Lukas G.; Wendel, Dominik; Krzyszton, Rafal; Lächelt, Ulrich; Wagner, Ernst; Rädler, Joachim O.; Wixforth, Achim (2016): Controllable Acoustic Mixing of Fluids in Microchannels for the Fabrication of Therapeutic Nanoparticles. In: Micromachines, Vol. 7, No. 9, 150 [PDF, 4MB]

Xie, Yuran; Killinger, Bryan; Moszczynska, Anna; Merkel, Olivia M. (2016): Targeted Delivery of siRNA to Transferrin Receptor Overexpressing Tumor Cells via Peptide Modified Polyethylenimine. In: Molecules, Vol. 21, No. 10, 1334 [PDF, 2MB]

Xie, Yuran; Kim, Na Hyung; Nadithe, Venkatareddy; Schalk, Dana; Thakur, Archana; Kılıç, Ayşe; Lum, Lawrence G.; Bassett, David J. P.; Merkel, Olivia M. (2016): Targeted delivery of siRNA to activated T cells via transferrin-polyethylenimine (Tf-PEI) as a potential therapy of asthma. In: Journal of Controlled Release, Vol. 229: pp. 120-129

Zhang, S.; Ulrich, M.; Gromnicka, A.; Havlíček, L.; Kryštof, V.; Jorda, R.; Strnad, M.; Vollmar, A. M.; Zahler, S. (2016): Anti-angiogenic effects of novel cyclin-dependent kinase inhibitors with a pyrazolo[4,3-d]pyrimidine scaffold. In: British Journal of Pharmacology, Vol. 173, No. 17: pp. 2645-2656

Zhang, Wei; Müller, Katharina; Kessel, Eva; Reinhard, Sören; He, Dongsheng; Klein, Philipp M.; Höhn, Miriam; Rödl, Wolfgang; Kempter, Susanne; Wagner, Ernst (2016): Targeted siRNA Delivery Using a Lipo-Oligoaminoamide Nanocore with an Influenza Peptide and Transferrin Shell. In: Advanced Healthcare Materials, Vol. 5, No. 12: pp. 1493-1504

Zhong, Qian; Merkel, Olivia M.; Reineke, Joshua J.; Rocha, Sandro R. P. da (2016): Effect of the Route of Administration and PEGylation of Poly(amidoamine) Dendrimers on Their Systemic and Lung Cellular Biodistribution. In: Molecular Pharmaceutics, Vol. 13, No. 6: pp. 1866-1878

2015

Arends, Fabienna; Nowald, Constantin; Pflieger, Kerstin; Boettcher, Kathrin; Zahler, Stefan; Lieleg, Oliver (2015): The Biophysical Properties of Basal Lamina Gels Depend on the Biochemical Composition of the Gel.
In: PLOS ONE 10(2), e0118090 [PDF, 2MB]

Bender, Julia; Engeholm, Maik; Ederer, Marion S.; Breu, Johannes; Moller, Thor C.; Michalakis, Stylianos; Rasko, Tamas; Wanker, Erich E.; Biel, Martin; Martinez, Karen L.; Wurst, Wolfgang; Deussing, Jan M. (2015): Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Clustering with MAGUKs Is Mediated via Its C-Terminal PDZ Binding Motif.
In: PLOS ONE 10(9), e0136768 [PDF, 20MB]

Braig, Simone; Schmidt, B. U. Sebastian; Stoiber, Katharina; Haendel, Chris; Moehn, Till; Werz, Oliver; Mueller, Rolf; Zahler, Stefan; Koeberle, Andreas; Kaes, Josef A.; Vollmar, Angelika M. (2015): Pharmacological targeting of membrane rigidity: implications on cancer cell migration and invasion. In: New Journal of Physics, Vol. 17, 083007 [PDF, 1MB]

Buchmann, Stefan; Sandmann, Gunther H.; Walz, Lars; Reichel, Thomas; Beitzel, Knut; Wexel, Gabriele; Tian, Weiwei; Battmann, Achim; Vogt, Stephan; Winter, Gerhard; Imhoff, Andreas B.: Growth factor release by vesicular phospholipid gels: in-vitro results and application for rotator cuff repair in a rat model. In: BMC Musculoskeletal Disorders 2015, 16:82 [PDF, 1MB]

Feodorova, Yana; Koch, Mirja; Bultman, Sebastian; Michalakis, Stylianos; Solovei, Irina (2015): Quick and reliable method for retina dissociation and separation of rod photoreceptor perikarya from adult mice. In: Methodsx, Vol. 2: pp. 39-46

Fuchs, Simone; Hsieh, Louise T.; Saarberg, Werner; Erdelmeier, Clemens A. J.; Wichelhaus, Thomas A.; Schaefer, Liliana; Koch, Egon; Fuerst, Robert (2015): Haemanthus coccineus extract and its main bioactive component narciclasine display profound anti-inflammatory activities in vitro and in vivo. In: Journal of Cellular and Molecular Medicine, Vol. 19, No. 5: pp. 1021-1032 [PDF, 718kB]

Liebl, Johanna; Zhang, Siwei; Moser, Markus; Agalarov, Yan; Demir, Cansaran Saygili; Hager, Bianca; Bibb, James A.; Adams, Ralf H.; Kiefer, Friedemann; Miura, Naoyuki; Petrova, Tatiana V.; Vollmar, Angelika M.; Zahler, Stefan (2015): Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. In: Nature Communications, Vol. 6, 7274 [PDF, 2MB]

Reichel, Christoph A.; Hessenauer, Maximilian E. T.; Pflieger, Kerstin; Rehberg, Markus; Kanse, Sandip M.; Zahler, Stefan; Krombach, Fritz; Berghaus, Alexander; Strieth, Sebastian (2015): Components of the Plasminogen Activation System Promote Engraftment of Porous Polyethylene Biomaterial via Common and Distinct Effects.
In: PLOS ONE 10(2), e0116883 [PDF, 4MB]

Rüben, Katharina; Wurzlbauer, Anne; Walte, Agnes; Sippl, Wolfgang; Bracher, Franz; Becker, Walter (2015): Selectivity Profiling and Biological Activity of Novel beta-Carbolines as Potent and Selective DYRK1 Kinase Inhibitors.
In: PLOS ONE 10(7), e0132453 [PDF, 4MB]

Schmitt, Andreas; Rödel, Philipp; Anamur, Cihad; Seeliger, Claudine; Imhoff, Andreas B.; Herbst, Elmar; Vogt, Stephan; Griensven, Martijn van; Winter, Gerhard; Engert, Julia (2015): Calcium Alginate Gels as Stem Cell Matrix - Making Paracrine Stem Cell Activity Available for Enhanced Healing after Surgery.
In: PLOS ONE 10(3), e0118937 [PDF, 1MB]

Tanimoto, Naoyuki; Sothilingam, Vithiyanjali; Kondo, Mineo; Biel, Martin; Humphries, Peter; Seeliger, Mathias W. (2015): Electroretinographic assessment of rod- and cone-mediated bipolar cell pathways using flicker stimuli in mice. In: Scientific Reports, Vol. 5, 10731 [PDF, 960kB]

2014

Arango-Gonzalez, Blanca; Trifunović, Dragana; Sahaboglu, Ayse; Kranz, Katharina; Michalakis, Stylianos; Farinelli, Pietro; Koch, Susanne; Koch, Fred; Cottet, Sandra; Janssen-Bienhold, Ulrike; Dedek, Karin; Biel, Martin; Zrenner, Eberhart; Euler, Thomas; Ekstrom, Per; Ueffing, Marius; Paquet-Durand, François (2014): Identification of a Common Non-Apoptotic Cell Death Mechanism in Hereditary Retinal Degeneration.
In: PLOS ONE 9(11), e112142 [PDF, 1MB]

Braig, S.; Wiedmann, R. M.; Liebl, J.; Singer, M.; Kubisch, R.; Schreiner, L.; Abhari, B. A.; Wagner, E.; Kazmaier, U.; Fulda, S.; Vollmar, Angelika M. (2014): Pretubulysin: a new option for the treatment of metastatic cancer. In: Cell Death & Disease, Vol. 5, e1001

Chen, Cheng-Chang; Keller, Marco; Hess, Martin; Schiffmann, Raphael; Urban, Nicole; Wolfgardt, Annette; Schaefer, Michael; Bracher, Franz; Biel, Martin; Wahl-Schott, Christian; Grimm, Christian (2014): A small molecule restores function to TRPML1 mutant isoforms responsible for mucolipidosis type IV. In: Nature Communications, Vol. 5, 4681 [PDF, 1MB]

Farinelli, P.; Perera, A.; Arango-Gonzalez, B.; Trifunovic, D.; Wagner, M.; Carell, T.; Biel, M.; Zrenner, E.; Michalakis, S.; Paquet-Durand, F.; Ekström, P. A. R. (2014): DNA methylation and differential gene regulation in photoreceptor cell death. In: Cell Death & Disease, Vol. 5, e1558 [PDF, 5MB]

Foerster, F.; Braig, S.; Moser, C.; Kubisch, R.; Busse, J.; Wagner, E.; Schmoeckel, E.; Mayr, D.; Schmitt, S.; Huettel, S.; Zischka, H.; Mueller, R.; Vollmar, Angelika M. (2014): Targeting the actin cytoskeleton: selective antitumor action via trapping PKCε. In: Cell Death & Disease, Vol. 5, e1398 [PDF, 3MB]

Grimm, Christian; Holdt, Lesca M.; Chen, Cheng-Chang; Hassan, Sami; Müller, Christoph; Jörs, Simone; Cuny, Hartmut; Kissing, Sandra; Schröder, Bernd; Butz, Elisabeth; Northoff, Bernd; Castonguay, Jan; Luber, Christian A.; Moser, Markus; Spahn, Saskia; Luellmann-Rauch, Renate; Fendel, Christina; Klugbauer, Norbert; Griesbeck, Oliver; Haas, Albert; Mann, Matthias; Bracher, Franz; Teupser, Daniel; Saftig, Paul; Biel, Martin; Wahl-Schott, Christian (2014): High susceptibility to fatty liver disease in two-pore channel 2-deficient mice. In: Nature Communications, Vol. 5, 4699 [PDF, 3MB]

Kern, Selina; Agarwal, Shruti; Huber, Kilian; Gehring, André P.; Strödke, Benjamin; Wirth, Christine C.; Brügl, Thomas; Abodo, Liliane Onambele; Dandekar, Thomas; Doerig, Christian; Fischer, Rainer; Tobin, Andrew B.; Alam, Mahmood M.; Bracher, Franz; Pradel, Gabriele (2014): Inhibition of the SR Protein-Phosphorylating CLK Kinases of Plasmodium falciparum Impairs Blood Stage Replication and Malaria Transmission.
In: PLOS ONE 9(9), e105732 [PDF, 3MB]

Kneidl, Barbara; Peller, Michael; Winter, Gerhard; Lindner, Lars H.; Hossann, Martin (2014): Thermosensitive liposomal drug delivery systems: state of the art review. In: International Journal of Nanomedicine, Vol. 9: pp. 4387-4398 [PDF, 4MB]

Kos, Petra; Lächelt, Ulrich; Herrmann, Annika; Mickler, Frauke M.; Krhač Levačić, Ana; Morys, Stephan; Bräuchle, Christoph; Wagner, Ernst (2014): Histidine-rich stabilized polyplexes for cMet-directed tumor-targeted gene transfer. In: Nanoscale, Vol. 7, No. 12: pp. 5350-5362 [PDF, 0B]

Neuner, Johanna; Filser, Severin; Michalakis, Stylianos; Biel, Martin; Herms, Jochen (2014): A30P alpha-Synuclein interferes with the stable integration of adult-born neurons into the olfactory network. In: Scientific Reports, Vol. 4, 3931 [PDF, 11MB]

Soltysinska, Ewa; Bentzen, Bo Hjorth; Barthmes, Maria; Hattel, Helle; Thrush, A. Brianne; Harper, Mary-Ellen; Qvortrup, Klaus; Larsen, Filip J.; Schiffer, Tomas A.; Losa-Reyna, Jose; Straubinger, Julia; Kniess, Angelina; Thomsen, Morten Bækgaard; Brüggemann, Andrea; Fenske, Stefanie; Biel, Martin; Ruth, Peter; Wahl-Schott, Christian; Boushel, Robert Christopher; Olesen, Søren-Peter; Lukowski, Robert (2014): KCNMA1 Encoded Cardiac BK Channels Afford Protection against Ischemia-Reperfusion Injury.
In: PLOS ONE 9(7), e103402 [PDF, 1MB]

2012

Herrmann, Jennifer; Elnakady, Yasser A.; Wiedmann, Romina M.; Ullrich, Angelika; Rohde, Manfred; Kazmaier, Uli; Vollmar, Angelika M.; Müller, Rolf (2012): Pretubulysin: from hypothetical biosynthetic intermediate to potential lead in tumor therapy.
In: PLOS ONE 7(5), e37416 [PDF, 1MB]

Kopp, Florian; Oak, Prajakta S.; Wagner, Ernst; Roidl, Andreas (2012): miR-200c sensitizes breast cancer cells to doxorubicin treatment by decreasing TrkB and Bmi1 expression.
In: PLOS ONE 7(11), e50469 [PDF, 700kB]

2011

Dussmann, Philipp; Pagel, Judith I.; Vogel, Sabina; Magnusson, Terese; Zimmermann, Rene; Wagner, Ernst; Schaper, Wolfgang; Ogris, Manfred; Deindl, Elisabeth: Live in vivo imaging of Egr-1 promoter activity during neonatal development, liver regeneration and wound healing. In: BMC Developmental Biology 2011, 11:28 [PDF, 2MB]

1994

Maass, Gerd; Zatloukal, Kurt; Schmidt, Walter; Berger, M.; Cotten, Matt; Wagner, Ernst; Birnstiel, Max L.; Buschle, M. (1994): The generation of tumor vaccines by adenovirus-enhanced transfection of cytokine genes into tumor cells. In: Skouteris, George G. (ed.) : Liver carcinogenesis. Berlin u.a.: Springer. pp. 467-479 [PDF, 1MB]

This list was generated on Wed Jul 24 02:36:08 2019 CEST.