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Anzahl der Publikationen auf dieser Ebene: 765

Zeitschriftenartikel

Ackermann, Thomas M.; Allmendinger, Lars; Höfner, Georg und Wanner, Klaus T. (2020): MS Binding Assays for Glycine Transporter 2 (GlyT2) Employing Org25543 as Reporter Ligand. In: Chemmedchem, Bd. 16, Nr. 1: S. 199-215 [PDF, 2MB]

Ackermann, Thomas M.; Bhokare, Karuna; Hoefner, Georg und Wanner, Klaus T. (2019): MS binding assays for GlyT1 based on Org24598 as nonlabelled reporter ligand. In: Neuropharmacology, Bd. 161, 107561

Adams, Friederike ORCID logoORCID: https://orcid.org/0000-0002-4362-0387; Zimmermann, Christoph M.; Baldassi, Domizia; Pehl, Thomas M. ORCID logoORCID: https://orcid.org/0000-0001-5930-8091; Weingarten, Philipp; Kachel, Iris; Kränzlein, Moritz ORCID logoORCID: https://orcid.org/0000-0001-9851-0735; Jürgens, David C.; Braubach, Peter ORCID logoORCID: https://orcid.org/0000-0003-3673-7779; Alexopoulos, Ioannis ORCID logoORCID: https://orcid.org/0000-0002-5601-2831; Wygrecka, Malgorzata ORCID logoORCID: https://orcid.org/0000-0002-3656-2932 und Merkel, Olivia M. ORCID logoORCID: https://orcid.org/0000-0002-4151-3916 (2023): Pulmonary siRNA Delivery with Sophisticated Amphiphilic Poly(Spermine Acrylamides) for the Treatment of Lung Fibrosis. In: Small [PDF, 3MB]

Adouvi, Gustave; Isigkeit, Laura; Lopez-Garcia, Ursula; Chaikuad, Apirat; Marschner, Julian A.; Schubert-Zsilavecz, Manfred und Merk, Daniel (2022): Rational Design of a New RXR Agonist Scaffold Enabling Single-Subtype Preference for RXR alpha, RXR beta, and RXR gamma. In: Journal of Medicinal Chemistry, Bd. 66, Nr. 1: S. 333-344

Agostini, Elisa; Winter, Gerhard und Engert, Julia (2017): Scale-up of water-based spider silk film casting using a film applicator. In: International Journal of Pharmaceutics, Bd. 532, Nr. 1: S. 13-20

Alamri, Ahmad M.; Kang, Keunsoo; Groeneveld, Svenja; Wang, Weisheng; Zhong, Xiaogang; Kallakury, Bhaskar; Hennighausen, Lothar; Liu, Xuefeng und Furth, Priscilla A. (2016): Primary cancer cell culture: mammary-optimized vs conditional reprogramming. In: Endocrine-Related Cancer, Bd. 23, Nr. 7: S. 535-554

Alex, Jimi M.; Corvaglia, Valentina; Hu, Xiaobo; Engilberge, Sylvain; Huc, Ivan und Crowley, Peter B. (2019): Crystal structure of a protein-aromatic foldamer composite: macromolecular chiral resolution. In: Chemical Communications, Bd. 55, Nr. 74: S. 11087-11090

Andima, Moses; Costabile, Gabriella; Isert, Lorenz; Ndakala, Albert J.; Derese, Solomon und Merkel, Olivia M. (2018): Evaluation of beta-Sitosterol Loaded PLGA and PEG-PLA Nanoparticles for Effective Treatment of Breast Cancer: Preparation, Physicochemical Characterization, and Antitumor Activity. In: Pharmaceutics, Bd. 10, Nr. 4, 232 [PDF, 3MB]

Andreß, Janina C.; Böck, Michael C.; Höfner, Georg und Wanner, Klaus T. (2020): Synthesis and biological evaluation of α- and β-hydroxy substituted amino acid derivatives as potential mGAT1-4 inhibitors. In: Medicinal Chemistry Research, Bd. 29, Nr. 8: S. 1321-1340 [PDF, 1MB]

Arango-Gonzalez, Blanca; Trifunović, Dragana; Sahaboglu, Ayse; Kranz, Katharina; Michalakis, Stylianos; Farinelli, Pietro; Koch, Susanne; Koch, Fred; Cottet, Sandra; Janssen-Bienhold, Ulrike; Dedek, Karin; Biel, Martin; Zrenner, Eberhart; Euler, Thomas; Ekstrom, Per; Ueffing, Marius und Paquet-Durand, François (2014): Identification of a Common Non-Apoptotic Cell Death Mechanism in Hereditary Retinal Degeneration.
In: PLOS ONE 9(11), e112142 [PDF, 1MB]

Ardelt, Maximilian A.; Fröhlich, Thomas; Martini, Emanuele; Müller, Martin; Kanitz, Veronika; Atzberger, Carina; Cantonati, Petra; Messner, Martina; Posselt, Laura; Lehr, Thorsten; Wojtyniak, Jan-Georg; Ulrich, Melanie; Arnold, Georg J.; König, Lars; Parazzoli, Dario; Zahler, Stefan; Rothenfusser, Simon; Mayr, Doris; Gerbes, Alexander; Scita, Giorgio; Vollmar, Angelika M. und Pachmayr, Johanna (2019): Inhibition of Cyclin-Dependent Kinase 5: A Strategy to Improve Sorafenib Response in Hepatocellular Carcinoma Therapy. In: Hepatology, Bd. 69, Nr. 1: S. 376-393

Arends, Fabienna; Nowald, Constantin; Pflieger, Kerstin; Boettcher, Kathrin; Zahler, Stefan und Lieleg, Oliver (2015): The Biophysical Properties of Basal Lamina Gels Depend on the Biochemical Composition of the Gel.
In: PLOS ONE 10(2), e0118090 [PDF, 2MB]

Arifi, Silvia; Zaienne, Daniel; Heering, Jan; Wein, Thomas; Zhubi, Rezart; Chaikuad, Apirat; Knapp, Stefan; Marschner, Julian A. und Merk, Daniel (2022): Fragment-based discovery of orphan nuclear receptor Nur77/NGFI-B ligands. In: Bioorganic Chemistry, Bd. 129, 106164

Arlt, E.; Arndt, L.; Breit, A.; Wennemuth, G.; Biel, M.; Wahl, C.; Gudermann, T.; Klugbauer, N. und Boekhoff, I. (2017): Two-pore channel protein 1 contributes to NAADP triggered acrosome reaction in spermatozoa. In: Reproduction in Domestic Animals, Bd. 52: S. 6-7

Arroyo-Araujo, Maria; Voelkl, Bernhard; Laloux, Clement; Novak, Janja; Koopmans, Bastijn; Waldron, Ann-Marie; Seiffert, Isabel; Stirling, Helen; Aulehner, Katharina; Janhunen, Sanna K.; Ramboz, Sylvie; Potschka, Heidrun; Holappa, Johanna; Fine, Tania; Loos, Maarten; Boulanger, Bruno; Wurbel, Hanno und Kas, Martien J. (2022): Systematic assessment of the replicability and generalizability of preclinical findings: Impact of protocol harmonization across laboratory sites.
In: PLOS Biology 20(11), e3001886

Auffenberg, Eva; Jurik, Angela; Mattusch, Corinna; Stoffel, Rainer; Genewsky, Andreas; Namendorf, Christian; Schmid, Roland M.; Rammes, Gerhard; Biel, Martin; Uhr, Manfred; Moosmang, Sven; Michalakis, Stylianos; Wotjak, Carsten T. und Thoeringer, Christoph K. (2016): Remote and reversible inhibition of neurons and circuits by small molecule induced potassium channel stabilization. In: Scientific Reports, Bd. 6, 19293 [PDF, 977kB]

Augustijn, Dillen; Mahapatra, Sujata; Streicher, Werner; Svilenov, Hristo; Kulakova, Ahna; Pohl, Christin und Rinnan, Asmund (2019): Novel non-linear curve fitting to resolve protein unfolding transitions in intrinsic fluorescence differential scanning fluorimetry. In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 142: S. 506-517

Badieyan, Zohreh Sadat; Berezhanskyy, Taras; Utzinger, Maximilian; Aneja, Manish Kumar; Emrich, Daniela; Erben, Reinhold; Schüler, Christiane; Altpeter, Philipp; Ferizi, Mehrije; Hasenpusch, Günther; Rudolph, Carsten und Plank, Christian (2016): Transcript-activated collagen matrix as sustained mRNA delivery system for bone regeneration. In: Journal of Controlled Release, Bd. 239: S. 137-148

Baldassi, Domizia; Ambike, Shubhankar; Feuerherd, Martin; Cheng, Cho-Chin; Peeler, David J.; Feldmann, Daniel P.; Porras-Gonzalez, Diana Leidy; Wei, Xin; Keller, Lea-Adriana; Kneidinger, Nikolaus; Stoleriu, Mircea Gabriel; Popp, Andreas; Burgstaller, Gerald; Pun, Suzie H.; Michler, Thomas und Merkel, Olivia M. (2022): Inhibition of SARS-CoV-2 replication in the lung with siRNA/VIPER polyplexes. In: Journal of Controlled Release, Bd. 345: S. 661-674

Baldassi, Domizia; Ngo, Thi My Hanh und Merkel, Olivia M. (2022): Optimization of Lung Surfactant Coating of siRNA Polyplexes for Pulmonary Delivery. In: Pharmaceutical Research [PDF, 6MB]

Baldassi, Domizia; Gabold, Bettina und Merkel, Olivia M. (2021): Air-Liquid Interface Cultures of the Healthy and Diseased Human Respiratory Tract: Promises, Challenges, and Future Directions. In: Advanced Nanobiomed Research, Bd. 1, Nr. 6, 2000111

Balsevich, Georgia; Häusl, Alexander S.; Meyer, Carola W.; Karamihalev, Stoyo; Feng, Xixi; Poehlmann, Max L.; Dournes, Carine; Uribe-Marino, Andres; Santarelli, Sara; Labermaier, Christiana; Hafner, Kathrin; Mao, Tianqi; Breitsamer, Michaela; Theodoropoulou, Marily; Namendorf, Christian; Uhr, Manfred; Paez-Pereda, Marcelo; Winter, Gerhard; Hausch, Felix; Chen, Alon; Tschöp, Matthias H.; Rein, Theo; Gassen, Nils C. und Schmidt, Mathias V. (2017): Stress-responsive FKBP51 regulates AKT2-AS160 signaling and metabolic function. In: Nature Communications, Bd. 8, 1725 [PDF, 1MB]

Bao, Maode; Shi, Run; Zhang, Kai; Zhao, Yanbo; Wang, Yanfang und Bao, Xuanwen (2019): Development of a membrane lipid metabolism-based signature to predict overall survival for personalized medicine in ccRCC patients. In: Epma Journal, Bd. 10, Nr. 4: S. 383-393

Bao, Xuanwen; Anastasov, Natasa; Wang, Yanfang und Rosemann, Michael (2019): A novel epigenetic signature for overall survival prediction in patients with breast cancer. In: Journal of Translational Medicine, Bd. 17, Nr. 1, 380

Bao, Xuanwen; Shi, Run; Zhang, Kai; Xin, Shan; Li, Xin; Zhao, Yanbo und Wang, Yanfang (18. September 2019): Immune Landscape of Invasive Ductal Carcinoma Tumor Microenvironment Identifies a Prognostic and Immunotherapeutically Relevant Gene Signature. In: Frontiers in Oncology, Bd. 9, 903: S. 1-15 [PDF, 2MB]

Bao, Xuanwen; Shi, Run; Zhao, Tianyu und Wang, Yanfang (2020): Immune landscape and a novel immunotherapy-related gene signature associated with clinical outcome in early-stage lung adenocarcinoma. In: Journal of Molecular Medicine-Jmm, Bd. 98, Nr. 6: S. 805-818

Bao, Xuanwen; Shi, Run; Zhao, Tianyu und Wang, Yanfang (2020): Mast cell-based molecular subtypes and signature associated with clinical outcome in early-stage lung adenocarcinoma. In: Molecular Oncology, Bd. 14, Nr. 5: S. 917-932

Bartel, Karin; Müller, Rolf und Schwarzenberg, Karin von (2019): Differential regulation of AMP-activated protein kinase in healthy and cancer cells explains why V-ATPase inhibition selectively kills cancer cells. In: Journal of Biological Chemistry, Bd. 294, Nr. 46: S. 17239-17248

Bartel, Karin; Pein, Helmut; Popper, Bastian; Schmitt, Sabine; Janaki-Raman, Sudha; Schulze, Almut; Lengauer, Florian; Koeberle, Andreas; Werz, Oliver; Zischka, Hans; Müller, Rolf; Vollmar, Angelika M. und Schwarzenberg, Karin von (2019): Connecting lysosomes and mitochondria - a novel role for lipid metabolism in cancer cell death. In: Cell Communication and Signaling, Bd. 17, 87

Bartel, Karin; Winzi, Maria; Ulrich, Melanie; Koeberle, Andreas; Menche, Dirk; Werz, Oliver; Müller, Rolf; Guck, Jochen; Vollmar, Angelika M. und Schwarzenberg, Karin von (2017): V-ATPase inhibition increases cancer cell stiffness and blocks membrane related Ras signaling - a new option for HCC therapy. In: Oncotarget, Bd. 8, Nr. 6: S. 9476-9487

Barthmes, Maria; Liao, Jun; Jiang, Youxing; Brüggemann, Andrea und Wahl-Schott, Christian (2016): Electrophysiological characterization of the archaeal transporter NCX_Mj using solid supported membrane technology. In: Journal of General Physiology, Bd. 147, Nr. 6: S. 485-496

Becirovic, Elvir ORCID logoORCID: https://orcid.org/0000-0001-8801-0649 (2022): Maybe you can turn me on: CRISPRa-based strategies for therapeutic applications. In: Cellular and Molecular Life Sciences, Bd. 79, Nr. 2, 130: S. 1-9 [PDF, 2MB]

Becirovic, Elvir; Böhm, Sybille; Nguyen, Ong N. P.; Riedmayr, Lisa M.; Hammelmann, Verena; Schön, Christian; Butz, Elisabeth S.; Wahl-Schott, Christian; Biel, Martin und Michalakis, Stylianos (2016): AAV Vectors for FRET-Based Analysis of Protein-Protein Interactions in Photoreceptor Outer Segments. In: Frontiers in Neuroscience, Bd. 10, 356 [PDF, 3MB]

Becirovic, Elvir; Böhm, Sybille; Nguyen, Ong Nam Phuong; Riedmayr, Lisa Maria; Koch, Mirja Annika; Schulze, Elisabeth; Kohl, Susanne; Borsch, Oliver; Santos-Ferreira, Tiago; Ader, Marius; Michalakis, Stylianos und Biel, Martin (2016): In Vivo Analysis of Disease-Associated Point Mutations Unveils Profound Differences in mRNA Splicing of Peripherin-2 in Rod and Cone Photoreceptors.
In: PLOS Genetics 12(1), e1005811 [PDF, 8MB]

Beck, Simon; Henß, Lisa; Weidner, Tatjana; Herrmann, Jennifer; Müller, Rolf; Chao, Yu-Kai; Grimm, Christian; Weber, Christopher; Sliva, Katja und Schnierle, Barbara S. (2016): Identification of entry inhibitors of Ebola virus pseudotyped vectors from a myxobacterial compound library. In: Antiviral Research, Bd. 132: S. 85-91

Bender, Julia; Engeholm, Maik; Ederer, Marion S.; Breu, Johannes; Moller, Thor C.; Michalakis, Stylianos; Rasko, Tamas; Wanker, Erich E.; Biel, Martin; Martinez, Karen L.; Wurst, Wolfgang und Deussing, Jan M. (2015): Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Clustering with MAGUKs Is Mediated via Its C-Terminal PDZ Binding Motif.
In: PLOS ONE 10(9), e0136768 [PDF, 20MB]

Benli-Hoppe, Teoman; Ozturk, Surhan Gol; Ozturk, Ozgur; Berger, Simone; Wagner, Ernst und Yazdi, Mina (2021): Transferrin Receptor Targeted Polyplexes Completely Comprised of Sequence-Defined Components. In: Macromolecular Rapid Communications, Bd. 43, Nr. 12, 2100602

Berger, Simone ORCID logoORCID: https://orcid.org/0000-0002-3572-7205; Berger, Martin ORCID logoORCID: https://orcid.org/0000-0002-0926-653X; Bantz, Christoph; Maskos, Michael und Wagner, Ernst ORCID logoORCID: https://orcid.org/0000-0001-8413-0934 (2022): Performance of nanoparticles for biomedical applications: The in vitro/in vivo discrepancy. In: Biophysics Reviews, Bd. 3, Nr. 1, 011303

Berger, Karin; Schopohl, Dorothee; Bollig, Antonia; Strobach, Dorothea; Rieger, Christina; Rublee, Dale und Ostermann, Helmut (2018): Burden of Oral Mucositis: A Systematic Review and Implications for Future Research. In: Oncology Research and Treatment, Bd. 41, Nr. 6: S. 399-405

Berger, Simone; Levacic, Ana Krhac; Hörterer, Elisa; Wilk, Ulrich; Benli-Hoppe, Teoman; Wang, Yanfang; Öztürk, Özgür; Luo, Jie und Wagner, Ernst (2021): Optimizing pDNA Lipo-polyplexes: A Balancing Act between Stability and Cargo Release. In: Biomacromolecules, Bd. 22, Nr. 3: S. 1282-1296

Berner, Carolin; Menzen, Tim; Winter, Gerhard und Svilenov, Hristo L. (2021): Combining Unfolding Reversibility Studies and Molecular Dynamics Simulations to Select Aggregation-Resistant Antibodies. In: Molecular Pharmaceutics, Bd. 18, Nr. 6: S. 2242-2253

Biel, M. (2017): Endolysosomal two-pore channels: from genes to function. In: Acta Physiologica, Bd. 221: S. 8

Bindl, Daniel ORCID logoORCID: https://orcid.org/0000-0002-2878-7592; Mandal, Pradeep K. ORCID logoORCID: https://orcid.org/0000-0001-5996-956X; Allmendinger, Lars und Huc, Ivan ORCID logoORCID: https://orcid.org/0000-0001-7036-9696 (2022): Discrete Stacked Dimers of Aromatic Oligoamide Helices. In: Angewandte Chemie International Edition, Bd. 61, Nr. 11 [PDF, 2MB]

Bindl, Daniel; Mandal, Pradeep K. und Huc, Ivan (2022): Generalizing the Aromatic delta-Amino Acid Foldamer Helix. In: Chemistry - A European Journal, Bd. 28, Nr. 31 [PDF, 1MB]

Bindl, Daniel; Heinemann, Elisabeth; Mandal, Pradeep K. und Huc, Ivan (2021): Quantitative helix handedness bias through a single H vs. CH3 stereochemical differentiation. In: Chemical Communications, Bd. 57, Nr. 46: S. 5662-5665

Bischoff, I.; Dai, B.; Stroedke, B.; Knapp, S.; Bracher, F. und Fuerst, R. (2016): First insights into the action of the carbazole derivative C81 and the role of its primary target BMP2K in the activated vascular endothelium. In: Naunyn-Schmiedebergs Archives of Pharmacology, Bd. 389, Nr. 1: S6-S6

Bischoff, Iris; Hornburger, Michael C.; Mayer, Bettina A.; Beyerle, Andrea; Wegener, Joachim und Fürst, Robert (2016): Pitfalls in assessing microvascular endothelial barrier function: impedance-based devices versus the classic macromolecular tracer assay. In: Scientific Reports, Bd. 6, 23671 [PDF, 1MB]

Blank, Thomas; Goldmann, Tobias; Koch, Mirja; Amann, Lukas; Schön, Christian; Bonin, Michael; Pang, Shengru; Prinz, Marco; Burnet, Michael; Wagner, Johanna E.; Biel, Martin und Michalakis, Stylianos (2018): Early Microglia Activation Precedes Photoreceptor Degeneration in a Mouse Model of CNGB1-Linked Retinitis Pigmentosa. In: Frontiers in Immunology, Bd. 8, 1930 [PDF, 7MB]

Blassmann, Ute; Hope, William; Roehr, Anka C.; Frey, Otto R.; Vetter-Kerkhoff, Cornelia; Thon, Niklas; Briegel, Josef und Huge, Volker (2019): CSF penetration of vancomycin in critical care patients with proven or suspected ventriculitis: a prospective observational study. In: Journal of Antimicrobial Chemotherapy, Bd. 74, Nr. 4: S. 991-996

Bluemel, Oliver; Anuschek, Moritz; Buecheler, Jakob W.; Hoelzl, Georg; Bechtold-Peters, Karoline und Friess, Wolfgang (2022): The effect of mAb and excipient cryoconcentration on long-term frozen storage stability - Part 1: Higher molecular weight species and subvisible particle formation. In: International Journal of Pharmaceutics: X, Bd. 4, 100108

Bluemel, Oliver; Buecheler, Jakob W.; Hauptmann, Astrid; Hoelzl, Georg; Bechtold-Peters, Karoline und Friess, Wolfgang (2022): The effect of mAb and excipient cryoconcentration on long-term frozen storage stability - part 2: Aggregate formation and oxidation. In: International Journal of Pharmaceutics: X, Bd. 4, 100109

Bluemel, Oliver; Pavlistic, Andraz; Likozar, Blaz; Rodrigues, Miguel A.; Geraldes, Vitor; Bechtold-Peters, Karoline und Friess, Wolfgang (2022): Computational fluid dynamic simulations of temperature, cryoconcentration, and stress time during large-scale freezing and thawing of monoclonal antibody solutions. In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 177: S. 107-112

Bluemel, Oliver; Rodrigues, A. Miguel; Buecheler, W. Jakob; Geraldes, Vitor; Hoelzl, Georg; Hauptmann, Astrid; Bechtold-Peters, Karoline und Friess, Wolfgang (2022): Evaluation of Two Novel Scale-Down Devices for Testing Monoclonal Antibody Aggregation During Large-Scale Freezing. In: Journal of Pharmaceutical Sciences, Bd. 111, Nr. 7: S. 1973-1983

Bluemel, Oliver; Buecheler, Jakob W.; Hauptmann, Astrid; Hoelzl, Georg; Bechtold-Peters, Karoline und Frieß, Wolfgang (2021): Scaling Down Large-Scale Thawing of Monoclonal Antibody Solutions: 3D Temperature Profiles, Changes in Concentration, and Density Gradients. In: Pharmaceutical Research, Bd. 38, Nr. 11: S. 1977-1989

Bluemel, Oliver; Buecheler, Jakob W.; Hauptmann, Astrid; Hoelzl, Georg; Bechtold-Peters, Karoline und Frieß, Wolfgang (2021): Scaling Down Large-Scale Thawing of Monoclonal Antibody Solutions: 3D Temperature Profiles, Changes in Concentration, and Density Gradients. In: Pharmaceutical research, Bd. 38, Nr. 11: S. 1977-1989 [PDF, 3MB]

Bluemel, Oliver; Buecheler, Jakob W.; Rodrigues, Miguel A.; Geraldes, Vitor; Hoelzl, Georg; Bechtold-Peters, Karoline und Friess, Wolfgang (2020): Cryoconcentration and 3D Temperature Profiles During Freezing of mAb Solutions in Large-Scale PET Bottles and a Novel Scale-Down Device. In: Pharmaceutical Research, Bd. 37, Nr. 9, 179

Bobak, Nicole; Feliciangeli, Sylvain; Chen, Cheng-Chang; Ben Soussia, Ismail; Bittner, Stefan; Pagnotta, Sophie; Ruck, Tobias; Biel, Martin; Wahl-Schott, Christian; Grimm, Christian; Meuth, Sven G. und Lesage, Florian (2017): Recombinant tandem of pore-domains in a Weakly Inward rectifying K+ channel 2 (TWIK2) forms active lysosomal channels. In: Scientific Reports, Bd. 7, 649 [PDF, 11MB]

Boehm, Sybille; Splith, Victoria; Riedmayr, Lisa Maria; Rotzer, Rene Dominik; Gasparoni, Gilles; Nordstroem, Karl J. V.; Wagner, Johanna Elisabeth; Hinrichsmeyer, Klara Sonnie; Walter, Joern; Wahl-Schott, Christian; Fenske, Stefanie; Biel, Martin; Michalakis, Stylianos und Becirovic, Elvir (2020): A gene therapy for inherited blindness using dCas9-VPR-mediated transcriptional activation. In: Science Advances, Bd. 6, Nr. 34, eaba5614

Bohn, Torsten; de Lera, Angel R.; Landrier, Jean-Francois; Carlsen, Harald; Merk, Daniel; Todt, Tilman; Renaut, Jenny und Ruehl, Ralph (2022): State-of-the-art methodological investigation of carotenoid activity and metabolism - from organic synthesis via metabolism to biological activity - exemplified by a novel retinoid signalling pathway. In: Food & Function, Bd. 14, Nr. 2: S. 621-638

Borland, Kayla; Diesend, Jan; Ito-Kureha, Taku; Heissmeyer, Vigo; Hammann, Christian; Buck, Amy H.; Michalakis, Stylianos und Kellner, Stefanie (2019): Production and Application of Stable Isotope-Labeled Internal Standards for RNA Modification Analysis. In: Genes, Bd. 10, Nr. 1, 26

Bornerie, Megane; Brion, Anais; Guichard, Gilles; Kichler, Antoine und Douat, Celine (2021): Delivery of siRNA by tailored cell-penetrating urea-based foldamers. In: Chemical Communications, Bd. 57, Nr. 12: S. 1458-1461

Borowiak, Malgorzata; Kuellmer, Florian; Gegenfurtner, Florian; Peil, Sebastian; Nasufovic, Veselin; Zahler, Stefan; Thorn-Seshold, Oliver; Trauner, Dirk und Arndt, Hans-Dieter (2020): Optical Manipulation of F-Actin with Photoswitchable Small Molecules. In: Journal of the American Chemical Society, Bd. 142, Nr. 20: S. 9240-9249

Bouwknegt, Jonna; Wiersma, Sanne J.; Ortiz-Merino, Raul A.; Doornenbal, Eline S. R.; Buitenhuis, Petrik; Giera, Martin; Mueller, Christoph und Pronk, Jack T. (2021): A squalene-hopene cyclase in Schizosaccharomyces japonicus represents a eukaryotic adaptation to sterol-limited anaerobic environments. In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 118, Nr. 32, e2105225118

Bracher, Franz (2020): Dimethylformamide Acetals and Bredereck's Reagent as Building Blocks in Natural Products Total Synthesis. In: Mini-Reviews in Organic Chemistry, Bd. 17, Nr. 1: S. 47-66

Bracher, Franz ORCID logoORCID: https://orcid.org/0000-0003-0009-8629 (2018): Methods for Arylethylation of Amines and Heteroarenes. In: Synopen, Bd. 2, Nr. 2: S. 96-104 [PDF, 2MB]

Bracher, Franz und Tremmel, Tim (2017): From Lead to Drug Utilizing a Mannich Reaction: The Topotecan Story. In: Archiv der Pharmazie, Bd. 350, Nr. 7, e1600236

Bracher, Franz und Tremmel, Tim (2017): The Chemistry of the Canthin-4-ones. In: Mini-Reviews in Organic Chemistry, Bd. 14, Nr. 2: S. 92-98

Braig, S.; Wiedmann, R. M.; Liebl, J.; Singer, M.; Kubisch, R.; Schreiner, L.; Abhari, B. A.; Wagner, E.; Kazmaier, U.; Fulda, S. und Vollmar, Angelika M. (2014): Pretubulysin: a new option for the treatment of metastatic cancer. In: Cell Death & Disease, Bd. 5, e1001

Braig, Simone (2018): Chemical genetics in tumor lipogenesis. In: Biotechnology Advances, Bd. 36, Nr. 6: S. 1724-1729

Braig, Simone; Schmidt, B. U. Sebastian; Stoiber, Katharina; Haendel, Chris; Moehn, Till; Werz, Oliver; Mueller, Rolf; Zahler, Stefan; Koeberle, Andreas; Kaes, Josef A. und Vollmar, Angelika M. (2015): Pharmacological targeting of membrane rigidity: implications on cancer cell migration and invasion. In: New Journal of Physics, Bd. 17, 083007 [PDF, 1MB]

Breitsamer, Michaela; Stulz, Anja; Heerklotz, Heiko H. und Winter, Gerhard (2019): Do interactions between protein and phospholipids influence the release behavior from lipid-based exenatide depot systems? In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 142: S. 61-69

Breitsamer, Michaela und Winter, Gerhard (2017): Needle-Free Injection of Vesicular Phospholipid Gels-A Novel Approach to Overcome an Administration Hurdle for Semisolid Depot Systems. In: Journal of Pharmaceutical Sciences, Bd. 106, Nr. 4: S. 968-972

Breitsamer, Michaela und Winter, Gerhard (2019): Vesicular phospholipid gels as drug delivery systems for small molecular weight drugs, peptides and proteins: State of the art review. In: International Journal of Pharmaceutics, Bd. 557: S. 1-8

Bryce, Nicole S.; Failes, Tim W.; Stehn, Justine R.; Baker, Karen; Zahler, Stefan; Arzhaeva, Yulia; Bischof, Leanne; Lyons, Ciaran; Dedova, Irina; Arndt, Greg M.; Gaus, Katharina; Goult, Benjamin T.; Hardeman, Edna C.; Gunning, Peter W. und Lock, John G. (2019): High-Content Imaging of Unbiased Chemical Perturbations Reveals that the Phenotypic Plasticity of the Actin Cytoskeleton Is Constrained. In: Cell Systems, Bd. 9, Nr. 5

Buchmann, Stefan; Sandmann, Gunther H.; Walz, Lars; Reichel, Thomas; Beitzel, Knut; Wexel, Gabriele; Tian, Weiwei; Battmann, Achim; Vogt, Stephan; Winter, Gerhard und Imhoff, Andreas B. (2015): Growth factor release by vesicular phospholipid gels: in-vitro results and application for rotator cuff repair in a rat model. In: BMC Musculoskeletal Disorders 16:82 [PDF, 1MB]

Burkard, Markus; Kohl, Susanne; Kratzig, Timm; Tanimoto, Naoyuki; Brennenstuhl, Christina; Bausch, Anne E.; Junger, Katrin; Reuter, Peggy; Sothilingam, Vithiyanjali; Beck, Susanne C.; Huber, Gesine; Ding, Xi-Qin; Mayer, Anja K.; Baumann, Britta; Weisschuh, Nicole; Zobor, Ditta; Hahn, Gesa-Astrid; Kellner, Ulrich; Venturelli, Sascha; Becirovic, Elvir; Charbel Issa, Peter; Koenekoop, Robert K.; Rudolph, Gunther; Heckenlively, John; Sieving, Paul; Weleber, Richard G.; Hamel, Christian; Zong, Xiangang; Biel, Martin; Lukowski, Robert; Seeliger, Matthias W.; Michalakis, Stylianos; Wissinger, Bernd und Ruth, Peter (2018): Accessory heterozygous mutations in cone photoreceptor CNGA3 exacerbate CNG channel-associated retinopathy. In: The Journal of Clinical Investigation, Bd. 128, Nr. 12: S. 5663-5675

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Jin, Yao; Adams, Friederike; Moeller, Judith; Isert, Lorenz; Zimmermann, Christoph M. M.; Keul, David und Merkel, Olivia M. M. (2022): Synthesis and Application of Low Molecular Weight PEI-Based Copolymers for siRNA Delivery with Smart Polymer Blends. In: Macromolecular Bioscience, Bd. 23, Nr. 2 [PDF, 2MB]

Jones, S. K. und Merkel, O. M. (2016): Tackling breast cancer chemoresistance with nano-formulated siRNA. In: Gene therapy, Bd. 23, Nr. 12: S. 821-828

Jones, Steven K.; Douglas, Kirk; Shields, Anthony F. und Merkel, Olivia M. (2018): Correlating quantitative tumor accumulation and gene knockdown using SPECT/CT and bioluminescence imaging within an orthotopic ovarian cancer model. In: Biomaterials, Bd. 178: S. 183-192

Jones, Steven K.; Sarkar, Anwesha; Feldmann, Daniel P.; Hoffmann, Peter und Merkel, Olivia M. (2017): Revisiting the value of competition assays in folate receptor-mediated drug delivery. In: Biomaterials, Bd. 138: S. 35-45

Joos, Markus; Schneider, Christian; Münchinger, Andreas; Moudrakovski, Igor; Usiskin, Robert; Maier, Joachim und Lotsch, Bettina V. (2021): Impact of hydration on ion transport in Li2Sn2S5 center dot xH(2)O. In: Journal of Materials Chemistry A, Bd. 9, Nr. 30: S. 16532-16544

Jourjine, Ilya A. P.; Bauernschmidt, Carolin; Müller, Christoph und Bracher, Franz (2022): A GC-MS Protocol for the Identification of Polycyclic Aromatic Alkaloids from Annonaceae. In: Molecules, Bd. 27, Nr. 23, 8217

Jourjine, Ilya A. P. ORCID logoORCID: https://orcid.org/0000-0001-5813-056X und Bracher, Franz ORCID logoORCID: https://orcid.org/0000-0003-0009-8629 (2023): Collective Total Synthesis of 4‐Azafluorenone Alkaloids. In: European Journal of Organic Chemistry, Bd. 26, Nr. 28 [PDF, 3MB]

Jourjine, Ilya A. P.; Zeisel, Lukas; Krauß, Jürgen und Bracher, Franz (2021): Synthesis of highly substituted fluorenones via metal-free TBHP-promoted oxidative cyclization of 2-(aminomethyl)biphenyls. Application to the total synthesis of nobilone. In: Beilstein Journal of Organic Chemistry, Bd. 17: S. 2668-2679

Junker, Julia; Chong, Isabelle; Kamp, Frits; Steiner, Harald; Giera, Martin; Müller, Christoph und Bracher, Franz (2019): Comparison of Strategies for the Determination of Sterol Sulfates via GC-MS Leading to a Novel Deconjugation-Derivatization Protocol. In: Molecules, Bd. 24, Nr. 13, 2353

Junker, Julia; Kamp, Frits; Winkler, Edith; Steiner, Harald; Bracher, Franz und Müller, Christoph (2021): Effective sample preparation procedure for the analysis of free neutral steroids, free steroid acids and sterol sulfates in different tissues by GC-MS. In: Journal of Steroid Biochemistry and Molecular Biology, Bd. 211, 105880

Jürgens, David Christian; Müller, Joschka T.; Nguyen, An Ny und Merkel, Olivia M. ORCID logoORCID: https://orcid.org/0000-0002-4151-3916 (2024): Tailoring lipid nanoparticles for T-cell targeting in allergic asthma: Insights into efficacy and specificity. In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 198, 114242 [PDF, 2MB]

Kaiser, Jesko; Gertzen, Christoph G. W.; Bernauer, Tamara; Hoefner, Georg; Niessen, Karin V.; Seeger, Thomas; Paintner, Franz F.; Wanner, Klaus T.; Worek, Franz; Thiermann, Horst und Gohlke, Holger (2022): A novel binding site in the nicotinic acetylcholine receptor for MB327 can explain its allosteric modulation relevant for organophosphorus-poisoning treatment. In: Toxicology Letters, Bd. 373: S. 160-171

Kajtna, Jacqueline; Tsang, Stephen H. und Koch, Susanne F. (2022): Late-stage rescue of visually guided behavior in the context of a significantly remodeled retinitis pigmentosa mouse model. In: Cellular and Molecular Life Sciences, Bd. 79, Nr. 3 [PDF, 13MB]

Kamlah, Alexandra und Bracher, Franz ORCID logoORCID: https://orcid.org/0000-0003-0009-8629 (2020): A Novel Approach to Highly Substituted β‐Carbolines via Reductive Ring Transformation of 2‐Acyl‐3‐isoxazolylindoles. In: European Journal of Organic Chemistry, Nr. 18: S. 2708-2719 [PDF, 1MB]

Kamlah, Alexandra und Bracher, Franz (2019): A Short Synthesis of the Plant Alkaloid 4-Methyl-2,6-naphthyridine. In: Letters in Organic Chemistry, Bd. 16, Nr. 12: S. 931-934

Kamlah, Alexandra; Lirk, Florian und Bracher, Franz (2016): A new approach to 1-substituted β-carbolines and isoquinolines utilizing tributyl[(Z)-2-ethoxyvinyl]stannane as a C-3,C-4 building block. In: Tetrahedron, Bd. 72, Nr. 6: S. 837-845

Kandil, Rima und Merkel, Olivia M. (2019): Recent progress of polymeric nanogels for gene delivery. In: Current Opinion in Colloid & Interface Science, Bd. 39: S. 11-23

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Karg, Cornelia A.; Parrakova, Lucia; Fuchs, Dietmar; Schennach, Harald; Kräutler, Bernhard; Moser, Simone und Gostner, Johanna M. (2022): A Chlorophyll-Derived Phylloxanthobilin Is a Potent Antioxidant That Modulates Immunometabolism in Human PBMC. In: Antioxidants, Bd. 11, Nr. 10 [PDF, 2MB]

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Karg, Cornelia A.; Schilling, Charlotte M.; Allmendinger, Lars und Moser, Simone (2019): Isolation, characterization, and antioxidative activity of a dioxobilin-type phylloxanthobilin from savoy cabbage. In: Journal of Porphyrins and Phthalocyanines, Bd. 23, Nr. 7-8: S. 881-888

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Karimova, Madina; Splith, Victoria; Karpinski, Janet; Pisabarro, M. Teresa und Buchholz, Frank (2016): Discovery of Nigri/nox and Panto/pox site-specific recombinase systems facilitates advanced genome engineering. In: Scientific Reports, Bd. 6, 30130 [PDF, 1MB]

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Keil, Tobias W. M.; Zimmermann, Christoph; Baldassi, Domizia; Adams, Friederike; Frieß, Wolfgang; Mehta, Aditi und Merkel, Olivia M. (2021): Impact of Crystalline and Amorphous Matrices on Successful Spray Drying of siRNA Polyplexes for Inhalation of Nano-in-Microparticles. In: Advanced Therapeutics, Bd. 4, Nr. 6, 2100073

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Keller, Lea-Adriana; Merkel, Olivia und Popp, Andreas (2021): Intranasal drug delivery: opportunities and toxicologic challenges during drug development. In: Drug Delivery and Translational Research, Bd. 12, Nr. 4: S. 735-757

Keller, Marco; Sauvageot-Witzku, Karl; Geisslinger, Franz; Urban, Nicole; Schaefer, Michael; Bartel, Karin und Bracher, Franz (2021): The ethoxycarbonyl group as both activating and protective group in N-acyl-Pictet-Spengler reactions using methoxystyrenes. A short approach to racemic 1-benzyltetrahydroisoquinoline alkaloids. In: Beilstein Journal of Organic Chemistry, Bd. 17: S. 2716-2725

Keller, Marco; Wolfgardt, Annette; Müller, Christoph; Wilcken, Rainer; Böckler, Frank M.; Oliaro-Bosso, Simonetta; Ferrante, Terenzio; Balliano, Gianni und Bracher, Franz (2016): Arylpiperidines as a new class of oxidosqualene cyclase inhibitors. In: European Journal of Medicinal Chemistry, Bd. 109: S. 13-22

Kern, Felix und Wanner, Klaus T. (2019): Screening oxime libraries by means of mass spectrometry (MS) binding assays: Identification of new highly potent inhibitors to optimized inhibitors gamma-aminobutyric acid transporter 1. In: Bioorganic & Medicinal Chemistry, Bd. 27, Nr. 7: S. 1232-1245

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Kerscher-Hack, Silke; Renukappa-Gutke, Thejavathi; Höfner, Georg und Wanner, Klaus T. (2016): Synthesis and biological evaluation of a series of N-alkylated imidazole alkanoic acids as mGAT3 selective GABA uptake inhibitors. In: European Journal of Medicinal Chemistry, Bd. 124: S. 852-880

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Mailaender-Sanchez, Daniela; Braunsdorf, Christina; Grumaz, Christian; Müller, Christoph; Lorenz, Stefan; Stevens, Philip; Wagener, Jeanette; Hebecker, Betty; Hube, Bernhard; Bracher, Franz; Sohn, Kai und Schaller, Martin (2017): Antifungal defense of probiotic Lactobacillus rhamnosus GG is mediated by blocking adhesion and nutrient depletion.
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Meinhold, Sarah; Bauer, Daniela; Huber, Jonas; Merkel, Ulrich; Weissl, Andreas; Zoldak, Gabriel und Rief, Matthias (2019): An Active, Ligand-Responsive Pulling Geometry Reports on Internal Signaling between Subdomains of the DnaK Nucleotide-Binding Domain in Single-Molecule Mechanical Experiments. In: Biochemistry, Bd. 58, Nr. 47: S. 4744-4750

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Melzer, Benedikt C.; Felber, Jan G. und Bracher, Franz (2018): Aminomethylation/hydrogenolysis as an alternative to direct methylation of metalated isoquinolines - a novel total synthesis of the alkaloid 7-hydroxy-6-methoxy-1-methylisoquinoline. In: Beilstein Journal of Organic Chemistry, Bd. 14: S. 130-134 [PDF, 261kB]

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Mukhopadhyay, Tufan K. ORCID logoORCID: https://orcid.org/0000-0001-8888-5373; Willems, Sabine ORCID logoORCID: https://orcid.org/0000-0002-9755-3394; Arp, Christopher J. ORCID logoORCID: https://orcid.org/0000-0002-5059-6178; Morstein, Johannes; Haake, Caleb T.; Merk, Daniel ORCID logoORCID: https://orcid.org/0000-0002-5359-8128 und Trauner, Dirk ORCID logoORCID: https://orcid.org/0000-0002-6782-6056 (2023): Development of Light‐Activated LXR Agonists. In: ChemMedChem, Bd. 18, Nr. 11 [PDF, 5MB]

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Müller, Christoph; Neugebauer, Thomas; Zill, Patrizia; Lass-Floerl, Cornelia; Bracher, Franz und Binder, Ulrike (2018): Sterol Composition of Clinically Relevant Mucorales and Changes Resulting from Posaconazole Treatment. In: Molecules, Bd. 23, Nr. 5, 1218 [PDF, 1MB]

Müller, Christoph; Wagner, Antonie L.; Rockinger, Ute; Winter, Gerhard und Bracher, Franz (2019): Development of a convenient method for the determination of dimethyl sulfoxide in lyophilised pharmaceuticals by static headspace gas chromatography-mass spectrometry. In: Analytical Methods, Bd. 11, Nr. 16: S. 2119-2122

Müller, Katharina; Klein, Philipp M.; Heissig, Philipp; Roidl, Andreas und Wagner, Ernst (2016): EGF receptor targeted lipo-oligocation polyplexes for antitumoral siRNA and miRNA delivery. In: Nanotechnology, Bd. 27, Nr. 46, 464001

Müller, Katherina; Kessel, Eva; Klein, Philipp M.; Höhn, Miriam und Wagner, Ernst (2016): Post-PEGylation of siRNA Lipo-oligoamino Amide Polyplexes Using Tetra-glutamylated Folic Acid as Ligand for Receptor-Targeted Delivery. In: Molecular Pharmaceutics, Bd. 13, Nr. 7: S. 2332-2345

Müller-Deku, Adrian und Thorn-Seshold, Oliver (2022): Exhaustive Catalytic ortho-Alkoxylation of Azobenzenes: Flexible Access to Functionally Diverse Yellow-Light-Responsive Photoswitches. In: Journal of Organic Chemistry, Bd. 87, Nr. 24: S. 16526-16531

Müller-Deku, Adrian; Meiring, Joyce C. M.; Loy, Kristina; Kraus, Yvonne; Heise, Constanze; Bingham, Rebekkah; Jansen, Klara I.; Qu, Xiaoyi; Bartolini, Francesca; Kapitein, Lukas C.; Akhmanova, Anna; Ahlfeld, Julia; Trauner, Dirk und Thorn-Seshold, Oliver (2020): Photoswitchable paclitaxel-based microtubule stabilisers allow optical control over the microtubule cytoskeleton. In: Nature communications, Bd. 11, Nr. 1, 4640 [PDF, 7MB]

Nadrigny, F.; Meur, Karim le; Schomburg, E. D.; Safavi-Abbasi, S. und Dibaj, P. (2017): Two-Photon Laser-Scanning Microscopy for Single and Repetitive Imaging of Dorsal and Lateral Spinal White Matter In Vivo. In: Physiological Research, Bd. 66, Nr. 3: S. 531-537

Nasiri, Hamid R.; Hohmann, Katharina; Hatemler, Melissa G.; Plodek, Alois; Bracher, Franz und Schwalbe, Harald (2017): In vitro production of reactive oxygen species (ROS) by sampangine. In: Medicinal Chemistry Research, Bd. 26, Nr. 6: S. 1170-1175

Neiens, Patrick; De Simone, Angela; Höfner, Georg und Wanner, Klaus T. (2018): Simultaneous Multiple MS Binding Assays for the Dopamine, Norepinephrine, and Serotonin Transporters. In: Chemmedchem, Bd. 13, Nr. 5: S. 453-463

Neiens, Patrick; De Simone, Angela; Ramershoven, Anna; Höfner, Georg; Allmendinger, Lars und Wanner, Klaus T. (2018): Development and validation of an LC-ESI-MS/MS method for the quantification of D-84, reboxetine and citalopram for their use in MS Binding Assays addressing the monoamine transporters hDAT, hSERT and hNET. In: Biomedical Chromatography, Bd. 32, Nr. 7, e4231

Neiens, Patrick; Höfner, Georg und Wanner, Klaus T. (2017): Determination of the enantiomeric purity of the selective dopamine transporter inhibitor (+)-R,R-4-(2-benzhydryloxyethyl)-1-(4-fluorobenzyl)piperidin-3-ol. In: Chirality, Bd. 29, Nr. 6: S. 294-303

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Nguyen, Ong Nam Phuong; Grimm, Christian; Schneider, Lina S.; Chao, Yu-Kai; Atzberger, Carina; Bartel, Karin; Watermann, Anna; Ulrich, Melanie; Mayr, Doris; Wahl-Schott, Christian; Biel, Martin und Vollmar, Angelika M. (2017): Two-Pore Channel Function Is Crucial for the Migration of Invasive Cancer Cells. In: Cancer Research, Bd. 77, Nr. 6: S. 1427-1438

Niessen, K. V.; Muschik, S.; Langguth, F.; Rappenglück, S.; Seeger, T.; Thiermann, H. und Worek, F. (2016): Functional analysis of Torpedo californica nicotinic acetylcholine receptors in multiple activation states by SSM-based electrophysiology. In: Toxicology Letters, Bd. 247: S. 1-10

Niessen, K. V.; Seeger, T.; Rappenglück, S.; Wein, T.; Höfner, G.; Wanner, K. T.; Thiermann, H. und Worek, F. (2018): In vitro pharmacological characterization of the bispyridinium non-oxime compound MB327 and its 2-and 3-regioisomers. In: Toxicology Letters, Bd. 293: S. 190-197

Nino-Pariente, Amaya; Arminan, Ana; Reinhard, Sören; Scholz, Claudia; Kos, Petra; Wagner, Ernst und Vicent, Maria J. (2017): Design of Poly-l-Glutamate-Based Complexes for pDNA Delivery (vol 10, 1700029, 2017). In: Macromolecular Bioscience, Bd. 17, Nr. 10, 1700245

Nino-Pariente, Amaya; Arminan, Ana; Reinhard, Sören; Scholz, Claudia; Wagner, Ernst und Vicent, Maria J. (2017): Design of Poly-l-Glutamate-Based Complexes for pDNA Delivery. In: Macromolecular Bioscience, Bd. 17, Nr. 10, 1700029

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Oliveira, Roberta Verissimo F.; de Souza, Wanderley; Voegerl, Katharina; Bracher, Franz; Benchimol, Marlene und Gadelha, Ana Paula R. (2022): In vitro effects of the 4-[(10H-phenothiazin-10-yl) methyl]-N-hydroxybenzamide on Giardia intestinalis trophozoites. In: Acta Tropica, Bd. 232, 106484

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Opolka-Hoffmann, Eugenia; Jordan, Gregor; Otteneder, Michael; Kieferle, Robin; Lechmann, Martin; Winter, Gerhard und Staack, Roland F. (2021): The impact of immunogenicity on therapeutic antibody pharmacokinetics: A preclinical evaluation of the effect of immune complex formation and antibody effector function on clearance. In: Mabs, Bd. 13, Nr. 1, e1995929

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Panossian, Alexander G.; Efferth, Thomas; Shikov, Alexander N.; Pozharitskaya, Olga N.; Kuchta, Kenny; Mukherjee, Pulok K.; Banerjee, Subhadip; Heinrich, Michael; Wu, Wanying; Guo, De-an und Wagner, Hildebert (2020): Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress- and aging-related diseases. In: Medicinal Research Reviews, Bd. 41, Nr. 1: S. 630-703

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Passi, Mehak und Zahler, Stefan (2021): Mechano-Signaling Aspects of Hepatocellular Carcinoma. In: Journal of Cancer, Bd. 12, Nr. 21: S. 6411-6421

Patel, Sajal Manubhai; Nail, Steven L.; Pikal, Michael J.; Geidobler, Raimund; Winter, Gerhard; Hawe, Andrea; Davagnino, Juan und Gupta, Shailaja Rambhatla (2017): Lyophilized Drug Product Cake Appearance: What Is Acceptable? In: Journal of Pharmaceutical Sciences, Bd. 106, Nr. 7: S. 1706-1721

Paulus, Constanze; Rebets, Yuriy; Tokovenko, Bogdan; Nadmid, Suvd; Terekhova, Larisa P.; Myronovskyi, Maksym; Zotchev, Sergey B.; Rückert, Christian; Braig, Simone; Zahler, Stefan; Kalinowski, Jörn und Luzhetskyy, Andriy (2017): New natural products identified by combined genomics-metabolomics profiling of marine Streptomyces sp MP131-18. In: Scientific Reports, Bd. 7, 42382 [PDF, 2MB]

Pavlou, M.; Shah, M.; Gikas, P.; Briggs, T.; Roberts, S. J. und Cheema, U. (2019): Osteomimetic matrix components alter cell migration and drug response in a 3D tumour-engineered osteosarcoma model. In: Acta Biomaterialia, Bd. 96: S. 247-257

Peng, Lun und Wagner, Ernst (2019): Polymeric Carriers for Nucleic Acid Delivery: Current Designs and Future Directions. In: Biomacromolecules, Bd. 20, Nr. 10: S. 3613-3626

Pergola, Carlo; Schubert, Katrin; Pace, Simona; Ziereisen, Jana; Nikels, Felix; Scherer, Olga; Hüttel, Stephan; Zahler, Stefan; Vollmar, Angelika M.; Weinigel, Christina; Rummler, Silke; Müller, Rolf; Raasch, Martin; Mosig, Alexander; Koeberle, Andreas und Werz, Oliver (2017): Modulation of actin dynamics as potential macrophage subtype-targeting anti-tumour strategy. In: Scientific Reports, Bd. 7, 41434 [PDF, 3MB]

Petersen-Jones, Simon M.; Occelli, Laurence M.; Biel, Martin und Michalakis, Stylianos (2019): Advancing Gene Therapy for PDE6A Retinitis Pigmentosa. In: Retinal Degenerative Diseases: Mechanisms and Experimental Therapy, Bd. 1185: S. 103-107

Petrera, Marilena; Wein, Thomas; Allmendinger, Lars; Sindelar, Miriam; Pabel, Jörg; Höfner, Georg und Wanner, Klaus T. (2016): Development of Highly Potent GAT1 Inhibitors: Synthesis of Nipecotic Acid Derivatives by Suzuki-Miyaura Cross-Coupling Reactions. In: ChemMedChem, Bd. 11, Nr. 5: S. 519-538

Pfitzer, Lisa; Moser, Christina; Gegenfurtner, Florian; Arner, Anja; Foerster, Florian; Atzberger, Carina; Zisis, Themistoklis; Kubisch-Dohmen, Rebekka; Busse, Johanna; Smith, Rebecca; Timinszky, Gyula; Kalinina, Olga V.; Müller, Rolf; Wagner, Ernst; Vollmar, Angelika M. und Zahler, Stefan (2019): Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy. In: Cell Death & Disease, Bd. 10, UNSP 302

Pivodová, V.; Zahler, S.; Karas, D.; Valentová, K. und Ulrichova, J. (2016): In vitro study of 2,3-dehydrosilybin and its galloyl esters as potential inhibitors of angiogenesis. In: Pharmazie, Bd. 71, Nr. 8: S. 478-483

Plesch, Eva; Chen, Cheng-Chang; Butz, Elisabeth; Rosato, Anna Scotto; Krogsaeter, Einar K.; Yinan, Hua; Bartel, Karin; Keller, Marco; Robaa, Dina; Teupser, Daniel; Holdt, Lesca M.; Vollmar, Angelika M.; Sippl, Wolfgang; Puertollano, Rosa; Medina, Diego; Biel, Martin; Wahl-Schott, Christian; Bracher, Franz und Grimm, Christian (2018): Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells. In: eLife, Bd. 7, e39720 [PDF, 4MB]

Plodek, Alois und Bracher, Franz (2016): New Perspectives in the Chemistry of Marine Pyridoacridine Alkaloids. In: Marine Drugs, Bd. 14, Nr. 2, 26 [PDF, 6MB]

Podkowa, A.; Sałat, K.; Malikowska, N.; Kern, F.; Pabel, J.; Kulig, K.; Wanner, K. T.; Wojcieszak, E. und Furgala, A. (2016): Anticonvulsant activity of a novel gamma-aminobutyric acid transporter subtype 1 inhibitor in mice. In: European Neuropsychopharmacology, Bd. 26: S286-S286

Pohl, Christin; Zalar, Matja; El Bialy, Inas; Indrakumar, Sowmya; Peters, Gunther H. J.; Friess, Wolfgang; Golovanov, Alexander P.; Streicher, Werner W.; Noergaard, Allan und Harris, Pernille (2020): The Effect of Point Mutations on the Biophysical Properties of an Antimicrobial Peptide: Development of a Screening Protocol for Peptide Stability Screening. In: Molecular Pharmaceutics, Bd. 17, Nr. 9: S. 3298-3313

Popp, Tobias A.; Tallant, Cynthia; Rogers, Catherine; Fedorov, Oleg; Brennan, Paul E.; Müller, Susanne; Knapp, Stefan und Bracher, Franz (2016): Development of Selective CBP/P300 Benzoxazepine Bromodomain Inhibitors. In: Journal of Medicinal Chemistry, Bd. 59, Nr. 19: S. 8889-8912

Popp, Tobias Alexander; Uhl, Edgar; Ong, Duc Nghia; Dittrich, Sebastian und Bracher, Franz (2016): A new approach to monoprotected 1,4-benzodiazepines via a one-pot N-deprotection/reductive cyclization procedure. In: Tetrahedron, Bd. 72, Nr. 13: S. 1668-1674

Pozo, Karine; Ishimatsu, Keisuke; Telange, Rahul; Takahashi, Masaya; Oltmann, Sarah; Zahler, Stefan und Bibb, James (2017): Novel Combinatorial Drug Therapy for MTC. In: Pancreas, Bd. 46, Nr. 3: S. 428-429

Pramanik, Susnata; Kauffmann, Brice; Hecht, Stefan; Ferrand, Yann und Huc, Ivan (2021): Light-mediated chiroptical switching of an achiral foldamer host in presence of a carbohydrate guest. In: Chemical Communications, Bd. 57, Nr. 1: S. 93-96

Pöhlmann, M. L.; Hartmann, J.; Harbich, D.; Schmid, B.; Häusl, A. S.; Dedic, N.; Feng, X.; Hausch, F.; Breitsamer, M.; Winter, G.; Deussing, J. und Schmidt, M. V. (2017): Unraveling the functional contribution of FKBP-51 in monoaminergic brain areas to stress vulnerability in mice. In: European Neuropsychopharmacology, Bd. 27: S39-S39

Pöhlmann, Max L.; Häusl, Alexander S.; Harbich, Daniela; Balsevich, Georgia; Engelhardt, Clara; Feng, Xixi; Breitsamer, Michaela; Hausch, Felix; Winter, Gerhard und Schmidt, Mathias V. (2018): Pharmacological Modulation of the Psychiatric Risk Factor FKBP51 Alters Efficiency of Common Antidepressant Drugs. In: Frontiers in Behavioral Neuroscience, Bd. 12, 262 [PDF, 1MB]

Rappenglück, Sebastian; Niessen, Karin V.; Seeger, Thomas; Worek, Franz; Thiermann, Horst und Wanner, Klaus T. (2017): Regioselective and Transition-Metal-Free Addition of tert-Butyl Magnesium Reagents to Pyridine Derivatives: A Convenient Method for the Synthesis of 3-Substituted 4-tert-Butylpyridine Derivatives. In: Synthesis-Stuttgart, Bd. 49, Nr. 17: S. 4055-4064

Rappenglück, Sebastian; Sichler, Sonja; Höfner, Georg; Wein, Thomas; Niessen, Karin V.; Seeger, Thomas; Paintner, Franz F.; Worek, Franz; Thiermann, Horst und Wanner, Klaus T. (2018): Synthesis of a Series of Non-Symmetric Bispyridinium and Related Compounds and Their Affinity Characterization at the Nicotinic Acetylcholine Receptor. In: Chemmedchem, Bd. 13, Nr. 24: S. 2653-2663

Rappenglück, Sebastian; Sichler, Sonja; Höfner, Georg; Wein, Thomas; Niessen, Karin V.; Seeger, Thomas; Paintner, Franz F.; Worek, Franz; Thiermann, Horst und Wanner, Klaus T. (2018): Synthesis of a Series of Structurally Diverse MB327 Derivatives and Their Affinity Characterization at the Nicotinic Acetylcholine Receptor. In: Chemmedchem, Bd. 13, Nr. 17: S. 1806-1816

Rarova, Lucie; Sedlak, David; Oklestkova, Jana; Steigerova, Jana; Liebl, Johanna; Zahler, Stefan; Bartunek, Petr; Kolar, Zdenek; Kohout, Ladislav; Kvasnica, Miroslav und Strnad, Miroslav (2018): The novel brassinosteroid analog BR4848 inhibits angiogenesis in human endothelial cells and induces apoptosis in human cancer cells in vitro. In: Journal of Steroid Biochemistry and Molecular Biology, Bd. 178: S. 263-271

Reddy, Post Sai; d'Estaintot, Beatrice Langlois; Granier, Thierry; Mackereth, Cameron D.; Fischer, Lucile und Huc, Ivan (2019): Structure Elucidation of Helical Aromatic Foldamer-Protein Complexes with Large Contact Surface Areas. In: Chemistry-A European Journal, Bd. 25, Nr. 47: S. 11042-11047

Reichel, Christoph A.; Hessenauer, Maximilian E. T.; Pflieger, Kerstin; Rehberg, Markus; Kanse, Sandip M.; Zahler, Stefan; Krombach, Fritz; Berghaus, Alexander und Strieth, Sebastian (2015): Components of the Plasminogen Activation System Promote Engraftment of Porous Polyethylene Biomaterial via Common and Distinct Effects.
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Reichel, Felix F.; Dauletbekov, Daniyar L.; Klein, Reinhild; Peters, Tobias; Ochakoyski, G. Alex; Seitz, Immanuel P.; Wilhelm, Barbara; Üffing, Marius; Biel, Martin; Wissinger, Bernd; Michalakis, Stylianos; Bartz-Schmidt, Karl Ulrich und Fischer, M. Dominik (2017): AAV8 Can Induce Innate and Adaptive Immune Response in the Primate Eye. In: Molecular therapy, Bd. 25, Nr. 12: S. 2648-2660

Reichel, Felix Friedrich; Peters, Tobias; Muehlfriedel, Regine; Biel, Martin; Paquet-Durand, Francois; Ueffing, Marius; Wissinger, Bernd; Bartz-Schmidt, Karl Ulrich; Fischer, M. Dominik und Michalakis, Stylianos (2016): Humoral immune response to subretinal AAV8 in non-human primates. In: Investigative Ophthalmology & Visual Science, Bd. 57, Nr. 12

Reinhard, Sören und Wagner, Ernst (2017): How to Tackle the Challenge of siRNA Delivery with Sequence-Defined Oligoamino Amides. In: Macromolecular Bioscience, Bd. 17, Nr. 1, 1600152

Reinhard, Sören; Wang, Yanfang; Dengler, Sebastian und Wagner, Ernst (2018): Precise Enzymatic Cleavage Sites for Improved Bioactivity of siRNA Lipo-Polyplexes. In: Bioconjugate Chemistry, Bd. 29, Nr. 11: S. 3649-3657

Reynders, Martin; Garścia, Małgorzata; Müller-Deku, Adrian; Wranik, Maximilian; Krauskopf, Kristina; Osa de la Rosa, Luis de la; Schaffer, Konstantin; Jötten, Anna; Rode, Alexander; Stierle, Valentin; Kraus, Yvonne; Baumgartner, Benedikt; Ali, Ahmed; Bubeneck, Andrei; Seal, Trina; Steinmetz, Michel O.; Paulitschke, Philipp und Thorn-Seshold, Oliver ORCID logoORCID: https://orcid.org/0000-0003-3981-651X (2024): A photo-SAR study of photoswitchable azobenzene tubulin-inhibiting antimitotics identifying a general method for near-quantitative photocontrol. In: Chemical Science, Bd. 15, Nr. 31: S. 12301-12309 [PDF, 4MB]

Reynders, Martin und Trauner, Dirk (2021): Optical control of targeted protein degradation. In: Cell Chemical Biology, Bd. 28, Nr. 7: S. 969-986

Riedmayr, Lisa M.; Hinrichsmeyer, Klara S.; Karguth, Nina; Böhm, Sybille; Splith, Victoria; Michalakis, Stylianos und Becirovic, Elvir (2022): dCas9-VPR-mediated transcriptional activation of functionally equivalent genes for gene therapy. In: Nature Protocols, Bd. 17, Nr. 3: S. 781-818

Riedmayr, Lisa M.; Boehm, Sybille; Biel, Martin und Becirovic, Elvir (2020): Enigmatic rhodopsin mutation creates an exceptionally strong splice acceptor site. In: Human Molecular Genetics, Bd. 29, Nr. 2: S. 295-304

Riedmayr, Lisa Maria; Böhm, Sybille; Michalakis, Stylianos und Becirovic, Elvir (2018): Construction and Cloning of Minigenes for in vivo Analysis of Potential Splice Mutations. In: Bio-Protocol, Bd. 8, Nr. 5, e2760

Rieser, Ruth; Menzen, Tim; Biel, Martin; Michalakis, Stylianos und Winter, Gerhard (2022): Systematic Studies on Stabilization of AAV Vector Formulations by Lyophilization. In: Journal of Pharmaceutical Sciences, Bd. 111, Nr. 8: S. 2288-2298

Rieser, Ruth; Koch, Johanna; Faccioli, Greta; Richter, Klaus; Menzen, Tim; Biel, Martin; Winter, Gerhard und Michalakis, Stylianos (2021): Comparison of Different Liquid Chromatography-Based Purification Strategies for Adeno-Associated Virus Vectors. In: Pharmaceutics, Bd. 13, Nr. 5, 748

Ritt, Nicolas; Berger, Simone; Wagner, Ernst und Zentel, Rudolf (2020): Versatile, Multifunctional Block Copolymers for the Self-Assembly of Well-Defined, Nontoxic pDNA Polyplexes. In: ACS Applied Polymer Materials, Bd. 2, Nr. 12: S. 5469-5481

Roche, Aisling; Gentiluomo, Lorenzo; Sibanda, Nicole; Roessner, Dierk; Friess, Wolfgang; Trainoff, Steven P. und Curtis, Robin (2021): Towards an improved prediction of concentrated antibody solution viscosity using the Huggins coefficient. In: Journal of Colloid and Interface Science, Bd. 607: S. 1813-1824

Roche, Aisling; Gentiluomo, Lorenzo; Sibanda, Nicole; Roessner, Dierk; Friess, Wolfgang; Trainoff, Steven P. und Curtis, Robin (2022): Towards an improved prediction of concentrated antibody solution viscosity using the Huggins coefficient. In: Journal of Colloid and Interface Science, Bd. 607, Nr. 2: S. 1813-1824

Rockinger, Ute; Funk, Martin und Winter, Gerhard (2021): Current Approaches of Preservation of Cells During (freeze-) Drying. In: Journal of Pharmaceutical Sciences, Bd. 110, Nr. 8: S. 2873-2893

Rockinger, Ute; Müller, Christoph; Bracher, Franz; Funk, Martin und Winter, Gerhard (2021): DMSO as new, counterintuitive excipient for freeze-drying human keratinocytes. In: European Journal of Pharmaceutical Sciences, Bd. 160, 105746

Rodrigues, Leticia; Kyriakos, Konstantinos; Schneider, Fabian; Dietz, Hendrik; Winter, Gerhard; Papadakis, Christine M. und Hubert, Madlen (2016): Characterization of Lipid-Based Hexosomes as Versatile Vaccine Carriers. In: Molecular Pharmaceutics, Bd. 13, Nr. 11: S. 3945-3954

Rodrigues, Leticia; Raftopoulos, Konstantinos N.; Schmidt, Signe Tandrup; Schneider, Fabian; Dietz, Hendrik; Rades, Thomas; Franzyk, Henrik; Pedersen, Anders Elm; Papadakis, Christine M.; Christensen, Dennis; Winter, Gerhard; Foged, Camilla und Hubert, Madlen (2018): Immune responses induced by nano-self-assembled lipid adjuvants based on a monomycoloyl glycerol analogue after vaccination with the Chlamydia trachomatis major outer membrane protein. In: Journal of Controlled Release, Bd. 285: S. 12-22

Rodrigues, Leticia; Schneider, Fabian; Zhang, Xiaohan; Larsson, Elin; Moodie, Lindon W. K.; Dietz, Hendrik; Papadakis, Christine M.; Winter, Gerhard; Lundmark, Richard und Hubert, Madlen (2019): Cellular uptake of self-assembled phytantriol-based hexosomes is independent of major endocytic machineries. In: Journal of Colloid and Interface Science, Bd. 553: S. 820-833

Rogers, Joseph M.; Kwon, Sunbum; Dawson, Simon J.; Mandal, Pradeep K.; Suga, Hiroaki und Huc, Ivan (2018): Ribosomal synthesis and folding of peptide-helical aromatic foldamer hybrids. In: Nature Chemistry, Bd. 10, Nr. 4: S. 405-412

Rospiccio, Marcello; Arsiccio, Andrea; Winter, Gerhard und Pisano, Roberto (2021): The Role of Cyclodextrins against Interface-Induced Denaturation in Pharmaceutical Formulations: A Molecular Dynamics Approach. In: Molecular Pharmaceutics, Bd. 18, Nr. 6: S. 2322-2333

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Wang, Shuaijun; Crevenna, Alvaro H.; Ugur, Ilke; Marion, Antoine; Antes, Iris; Kazmaier, Uli; Hoyer, Maria; Lamb, Don C.; Gegenfurtner, Florian; Kliesmetes, Zane; Ziegenhain, Christoph; Enard, Wolfgang; Vollmar, Angelika und Zahler, Stefan (2019): Actin stabilizing compounds show specific biological effects due to their binding mode. In: Scientific Reports, Bd. 9, 9731 [PDF, 5MB]

Wang, Shuaijun; Gegenfurtner, Florian A.; Crevenna, Alvaro H.; Ziegenhain, Christoph; Kliesmete, Zane; Enard, Wolfgang; Müller, Rolf; Vollmar, Angelika M.; Schneider, Sabine und Zahler, Stefan (2019): Chivosazole A Modulates Protein Protein Interactions of Actin. In: Journal of Natural Products, Bd. 82, Nr. 7: S. 1961-1970

Wang, Shuaijun; Meixner, Maximilian; Yu, Lushuang; Zhuo, Ling; Karmann, Lisa; Kazmaier, Uli; Vollmar, Angelika M.; Antes, Iris und Zahler, Stefan (2021): Turning the Actin Nucleating Compound Miuraenamide into Nucleation Inhibitors. In: ACS Omega, Bd. 6, Nr. 34: S. 22165-22172

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Wang, Yanfang und Wagner, Ernst (2020): Non-Viral Targeted Nucleic Acid Delivery: Apply Sequences for Optimization. In: Pharmaceutics, Bd. 12, Nr. 9, 888

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Wang, Yanfang; Zhang, Quanli; Gao, Zhaojia; Xin, Shan; Zhao, Yando; Zhang, Kai; Shi, Run und Bao, Xuanwen (2019): A novel 4-gene signature for overall survival prediction in lung adenocarcinoma patients with lymph node metastasis. In: Cancer Cell International, Bd. 19, 100

Wanner, Randy; Breitsprecher, Dennis; Duhr, Stefan; Baaske, Philipp und Winter, Gerhard (2017): Thermo-Optical Protein Characterization for Straightforward Preformulation Development. In: Journal of Pharmaceutical Sciences, Bd. 106, Nr. 10: S. 2955-2958

Wathoni, Nasrul; An Ny, Nguyen; Rusdin, Agus; Umar, Abd Kakhar; Mohammed, Ahmed Fouad Abdelwahab; Motoyama, Keiichi; Joni, I. Made und Muchtaridi, Muchtaridi (2020): Enteric-Coated Strategies in Colorectal Cancer Nanoparticle Drug Delivery System. In: Drug Design Development and Therapy, Bd. 14: S. 4387-4405

Wein, Thomas; Höfner, Georg; Rappenglück, Sebastian; Sichler, Sonja; Niessen, Karin V.; Seeger, Thomas; Worek, Franz; Thiermann, Horst und Wanner, Klaus T. (2018): Searching for putative binding sites of the bispyridinium compound MB327 in the nicotinic acetylcholine receptor. In: Toxicology Letters, Bd. 293: S. 184-189

Wein, Thomas; Petrera, Marilena; Allmendinger, Lars; Höfner, Georg; Pabel, Jörg und Wanner, Klaus T. (2016): Different Binding Modes of Small and Large Binders of GAT1. In: ChemMedChem, Bd. 11, Nr. 5: S. 509-518

Wein, Thomas; Wanner, Klaus T.; Rappenglueck, Sebastian; Sichler, Sonja; Niessen, Karin; Seeger, Thomas; Worek, Franz und Thiermann, Horst (2019): New Resensitizers for the Nicotinic Acetylcholine Receptor by Ligand-Based Pharmacophore Modeling. In: Current Computer-Aided Drug Design, Bd. 15, Nr. 1: S. 104-109

Weippert, Valentin und Johrendt, Dirk (2019): High-pressure synthesis and crystal structure of SrGa4As4. In: Acta Crystallographica Section E-Crystallographic Communications, Bd. 75

Werner, Benjamin Patrick; Schoneich, Christian und Winter, Gerhard (2019): Silicone Oil-Free Polymer Syringes for the Storage of Therapeutic Proteins. In: Journal of Pharmaceutical Sciences, Bd. 108, Nr. 3: S. 1148-1160

Werner, Benjamin Patrick und Winter, Gerhard (2018): Expanding Bedside Filtration-A Powerful Tool to Protect Patients From Protein Aggregates. In: Journal of Pharmaceutical Sciences, Bd. 107, Nr. 11: S. 2775-2788

West, Lorna Marie; Vetter-Kerkhoff, Cornelia; Miljkovic, Nenad und Frontini, Roberto (2018): Is there a need for a hospital pharmacy common training framework? Review of the literature on the impact of educational interventions on health outcome. In: European Journal of Hospital Pharmacy-Science and Practice, Bd. 25, Nr. 1: S. 6-9

Westerhausen, Christoph; Schnitzler, Lukas G.; Wendel, Dominik; Krzyszton, Rafal; Lächelt, Ulrich; Wagner, Ernst; Rädler, Joachim O. und Wixforth, Achim (2016): Controllable Acoustic Mixing of Fluids in Microchannels for the Fabrication of Therapeutic Nanoparticles. In: Micromachines, Bd. 7, Nr. 9, 150 [PDF, 4MB]

Willems, Sabine; Marschner, Julian A.; Kilu, Whitney; Faudone, Giuseppe; Busch, Romy; Duensing‐Kropp, Silke; Heering, Jan und Merk, Daniel (30. Juni 2022): Nurr1 Modulation Mediates Neuroprotective Effects of Statins. In: Advanced Science, Bd. 9, Nr. 18 [PDF, 4MB]

Willems, Sabine und Merk, Daniel (2022): Medicinal Chemistry and Chemical Biology of Nurr1 Modulators: An Emerging Strategy in Neurodegeneration. In: Journal of Medicinal Chemistry, Bd. 65, Nr. 14: S. 9548-9563

Willems, Sabine; Mueller, Marcel; Ohrndorf, Julia; Heering, Jan; Proschak, Ewgenij und Merk, Daniel (2022): Scaffold Hopping from Amodiaquine to Novel Nurr1 Agonist Chemotypes via Microscale Analogue Libraries. In: Chemmedchem, Bd. 17, Nr. 8, e202200026

Winkeljann, Benjamin; Keul, David C. und Merkel, Olivia M. (2022): Engineering poly- and micelleplexes for nucleic acid delivery-A reflection on their endosomal escape. In: Journal of Controlled Release, Bd. 353: S. 518-534

Wollnitzke, Philipp; Essig, Sebastian; Goelz, Jan Philipp; Schwarzenberg, Karin von und Menche, Dirk (2020): Total Synthesis of Ajudazol A by a Modular Oxazole Diversification Strategy. In: Organic Letters, Bd. 22, Nr. 16: S. 6344-6348

Woortman, Dirk Volker; Jürgens, Sophie; Untergehrer, Martin; Rechenberger, Julia; Fuchs, Monika; Mehlmer, Norbert; Qoura, Farah; Eckel, Georg; Stoehr, Michael; Osswald, Patrick; Le Clercq, Patrick; Hintermann, Lukas; Weuster-Botz, Dirk; Bracher, Franz und Brueck, Thomas (2020): Greener aromatic antioxidants for aviation and beyond. In: Sustainable Energy & Fuels, Bd. 4, Nr. 5: S. 2153-2163

Wurzlbauer, Anne; Rueben, Katharina; Guerdal, Ece; Chaikuad, Apirat; Knapp, Stefan; Sippl, Wolfgang; Becker, Walter und Bracher, Franz (2020): How to Separate Kinase Inhibition from Undesired Monoamine Oxidase A Inhibition-The Development of the DYRK1A Inhibitor AnnH75 from the Alkaloid Harmine. In: Molecules, Bd. 25, Nr. 24, 5962

Wuttke, Stefan; Zimpel, Andreas; Bein, Thomas; Braig, Simone; Stoiber, Katharina; Vollmar, Angelika; Müller, Dominik; Haastert-Talini, Kirsten; Schaeske, Jörn; Stiesch, Meike; Zahn, Gesa; Mohmeyer, Alexander; Behrens, Peter; Eickelberg, Oliver; Bölükbas, Deniz A. und Meiners, Silke (2017): Validating Metal-Organic Framework Nanoparticles for Their Nanosafety in Diverse Biomedical Applications. In: Advanced Healthcare Materials, Bd. 6, Nr. 2, 1600818

Währa, Mark; Allmendinger, Lars; Höfner, Georg ORCID logoORCID: https://orcid.org/0000-0002-7957-4503 und Wanner, Klaus T. ORCID logoORCID: https://orcid.org/0000-0003-4399-1425 (2023): Benocyclidine (BTCP) as Non‐labelled Reporter Ligand for MS Binding Assays for the PCP Ion Channel Binding Site of the Desensitized Torpedo Nicotinic Acetylcholine Receptor (nAChR). In: ChemMedChem, Bd. 18, Nr. 10 [PDF, 1MB]

Xie, Ying; Hang, Yu; Wang, Yazhe; Sleightholm, Richard; Prajapati, Dipakkumar R.; Bader, Johannes; Yu, Ao; Tang, Weimin; Jaramillo, Lee; Li, Jing; Singh, Rakesh K. und Oupicky, David (2020): Stromal Modulation and Treatment of Metastatic Pancreatic Cancer with Local Intraperitoneal Triple miRNA/siRNA Nanotherapy. In: ACS Nano, Bd. 14, Nr. 1: S. 255-271

Xie, Yuran; Killinger, Bryan; Moszczynska, Anna und Merkel, Olivia M. (2016): Targeted Delivery of siRNA to Transferrin Receptor Overexpressing Tumor Cells via Peptide Modified Polyethylenimine. In: Molecules, Bd. 21, Nr. 10, 1334 [PDF, 2MB]

Xie, Yuran; Kim, Na Hyung; Nadithe, Venkatareddy; Schalk, Dana; Thakur, Archana; Kılıç, Ayşe; Lum, Lawrence G.; Bassett, David J. P. und Merkel, Olivia M. (2016): Targeted delivery of siRNA to activated T cells via transferrin-polyethylenimine (Tf-PEI) as a potential therapy of asthma. In: Journal of Controlled Release, Bd. 229: S. 120-129

Yao, Chenhao; Kauffmann, Brice; Huc, Ivan und Ferrand, Yann (2022): Self-assembling figure-of-eight and pseudoplectoneme aromatic oligoamide ribbons. In: Chemical Communications, Bd. 58, Nr. 38: S. 5789-5792

Yazdi, Mina; Pöhmerer, Jana; Hasanzadeh Kafshgari, Morteza; Seidl, Johanna; Grau, Melina; Höhn, Miriam; Vetter, Victoria; Hoch, Cosima C.; Wollenberg, Barbara; Multhoff, Gabriele; Bashiri Dezfouli, Ali und Wagner, Ernst ORCID logoORCID: https://orcid.org/0000-0001-8413-0934 (2024): In Vivo Endothelial Cell Gene Silencing by siRNA‐LNPs Tuned with Lipoamino Bundle Chemical and Ligand Targeting. In: Small [PDF, 6MB]

Yoluç, Yasemin; Logt, Erik van de und Kellner-Kaiser, Stefanie (2021): The Stress-Dependent Dynamics of Saccharomyces cerevisiae tRNA and rRNA Modification Profiles. In: Genes, Bd. 12, Nr. 9, 1344

Yoneda, Saki; Niederleitner, Bertram; Wiggenhorn, Michael; Koga, Hiroki; Totoki, Shinichiro; Krayukhina, Elena; Friess, Wolfgang und Uchiyama, Susumu (2019): Quantitative Laser Diffraction for Quantification of Protein Aggregates: Comparison With Resonant Mass Measurement, Nanoparticle Tracking Analysis, Flow Imaging, and Light Obscuration. In: Journal of Pharmaceutical Sciences, Bd. 108, Nr. 1: S. 755-762

Yordanova, Yordanka; Vanderlinden, Willem; Stoll, Raphael; Rüdiger, Daniel; Tosstorff, Andreas; Zaremba, Wolfgang; Winter, Gerhard; Zahler, Stefan und Friess, Wolfgang (2018): Zn2+-triggered self-assembly of Gonadorelin [6-D-Phe] to produce nanostructures and fibrils. In: Scientific Reports, Bd. 8, 11280 [PDF, 3MB]

Yuan, Yu; Jaslan, Dawid; Rahman, Taufiq; Bolsover, Stephen R.; Arige, Vikas; Wagner, Larry E.; Abrahamian, Carla; Tang, Rachel; Keller, Marco; Hartmann, Jonas; Rosato, Anna S.; Weiden, Eva-Maria; Bracher, Franz; Yule, David I.; Grimm, Christian und Patel, Sandip (2022): Segregated cation flux by TPC2 biases Ca2+ signaling through lysosomes. In: Nature Communications, Bd. 13, Nr. 1, 4481

Yuan, Yu; Kilpatrick, Bethan S.; Gerndt, Susanne; Bracher, Franz; Grimm, Christian; Schapira, Anthony H. und Patel, Sandip (2021): The lysosomotrope GPN mobilises Ca2+ from acidic organelles. In: Journal of Cell Science, Bd. 134, Nr. 6, jcs256578

Zahler, Stefan (2020): Nuclear actin in cancer biology. In: International review of cell and molecular biology, Bd. 355: S. 53-66

Zaienne, Daniel; Arifi, Silvia; Marschner, Julian A.; Heering, Jan und Merk, Daniel (2022): Druggability Evaluation of the Neuron Derived Orphan Receptor (NOR-1) Reveals Inverse NOR-1 Agonists. In: Chemmedchem, Bd. 17, Nr. 16, e202200259

Zaienne, Daniel; Isigkeit, Laura; Marschner, Julian A.; Duensing‐Kropp, Silke; Höfner, Georg und Merk, Daniel ORCID logoORCID: https://orcid.org/0000-0002-5359-8128 (2023): Structural Modification of the Natural Product Valerenic Acid Tunes RXR Homodimer Agonism. In: ChemMedChem, Bd. 18, Nr. 21 [PDF, 895kB]

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Zareba, Paula; Gryzlo, Beata; Malawska, Katarzyna; Salat, Kinga; Höfner, Georg C.; Nowaczyk, Alicja; Fijalkowski, Lukasz; Rapacz, Anna; Podkowa, Adrian; Furgala, Anna; Zmudzki, Pawel; Wanner, Klaus T.; Malawska, Barbara und Kulig, Katarzyna (2020): Novel mouse GABA uptake inhibitors with enhanced inhibitory activity toward mGAT3/4 and their effect on pain threshold in mice. In: European Journal of Medicinal Chemistry, Bd. 188, 111920

Zareba, Paula; Salat, Kinga; Höfner, Georg C.; Latka, Kamil; Bajda, Marek; Latacz, Gniewomir; Kotniewicz, Krzysztof; Rapacz, Anna; Podkowa, Adrian; Maj, Maciej; Jozwiak, Krzysztof; Filipek, Barbara; Wanner, Klaus T.; Malawska, Barbara und Kulig, Katarzyna (2021): Development of tricyclic N-benzyl-4-hydroxybutanamide derivatives as inhibitors of GABA transporters mGAT1-4 with anticonvulsant, antinociceptive, and antidepressant activity. In: European Journal of Medicinal Chemistry, Bd. 221, 113512

Zeisel, Lukas; Felber, Jan G.; Scholzen, Karoline C.; Poczka, Lena; Cheff, Dorian; Maier, Martin S.; Cheng, Qing; Shen, Min; Hall, Matthew D.; Arner, Elias S. J.; Thorn-Seshold, Julia und Thorn-Seshold, Oliver (2022): Selective cellular probes for mammalian thioredoxin reductase TrxR1: Rational design of RX1, a modular 1,2-thiaselenane redox probe. In: Chem, Bd. 8, Nr. 5: S. 1493-1517

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Zhang, Peng und Wagner, Ernst (2017): History of Polymeric Gene Delivery Systems. In: Topics in Current Chemistry, Bd. 375, Nr. 2, 26

Zhang, S.; Ulrich, M.; Gromnicka, A.; Havlíček, L.; Kryštof, V.; Jorda, R.; Strnad, M.; Vollmar, A. M. und Zahler, S. (2016): Anti-angiogenic effects of novel cyclin-dependent kinase inhibitors with a pyrazolo[4,3-d]pyrimidine scaffold. In: British Journal of Pharmacology, Bd. 173, Nr. 17: S. 2645-2656

Zhang, Wei; Müller, Katharina; Kessel, Eva; Reinhard, Sören; He, Dongsheng; Klein, Philipp M.; Höhn, Miriam; Rödl, Wolfgang; Kempter, Susanne und Wagner, Ernst (2016): Targeted siRNA Delivery Using a Lipo-Oligoaminoamide Nanocore with an Influenza Peptide and Transferrin Shell. In: Advanced Healthcare Materials, Bd. 5, Nr. 12: S. 1493-1504

Zhang, Xiaohan; Chytil, Petr; Etrych, Tomas; Liu, Weiwei; Rodrigues, Leticia; Winter, Gerhard; Filippov, Sergey K. und Papadakis, Christine M. (2018): Binding of HSA to Macromolecular rho HPMA Based Nanoparticles for Drug Delivery: An Investigation Using Fluorescence Methods. In: Langmuir, Bd. 34, Nr. 27: S. 7998-8006

Zhong, Qian; Merkel, Olivia M.; Reineke, Joshua J. und Rocha, Sandro R. P. da (2016): Effect of the Route of Administration and PEGylation of Poly(amidoamine) Dendrimers on Their Systemic and Lung Cellular Biodistribution. In: Molecular Pharmaceutics, Bd. 13, Nr. 6: S. 1866-1878

Zhong, Yulong; Kauffmann, Brice; Xu, Wenwu; Lu, Zhong-Lin; Ferrand, Yann; Huc, Ivan; Zeng, Xiao Cheng; Liu, Rui und Gong, Bing (2020): Multiturn Hollow Helices: Synthesis and Folding of Long Aromatic Oligoamides. In: Organic Letters, Bd. 22, Nr. 17: S. 6938-6942

Ziach, Krzysztof; Chollet, Celine; Parissi, Vincent; Prabhakaran, Panchami; Marchivie, Mathieu; Corvaglia, Valentina; Bose, Partha Pratim; Laxmi-Reddy, Katta; Godde, Frederic; Schmitter, Jean-Marie; Chaignepain, Stephane; Pourquier, Philippe und Huc, Ivan (2018): Single helically folded aromatic oligoamides that mimic the charge surface of double-stranded B-DNA. In: Nature Chemistry, Bd. 10, Nr. 5: S. 511-518

Zimmermann, Christoph M.; Baldassi, Domizia; Chan, Karen; Adams, Nathan B. P.; Neumann, Alina; Porras-Gonzalez, Diana Leidy; Wei, Xin; Kneidinger, Nikolaus; Stoleriu, Mircea Gabriel; Burgstaller, Gerald; Witzigmann, Dominik; Luciani, Paola und Merkel, Olivia M. (2022): Spray drying siRNA-lipid nanoparticles for dry powder pulmonary delivery. In: Journal of Controlled Release, Bd. 351: S. 137-150

Zisis, Themistoklis; Brueckner, David B.; Brandstaetter, Tom; Siow, Wei Xiong; d'Alessandro, Joseph; Vollmar, Angelika M.; Broedersz, Chase P. und Zahler, Stefan (2022): Disentangling cadherin-mediated cell-cell interactions in collective cancer cell migration. In: Biophysical Journal, Bd. 121, Nr. 1: S. 44-60

Zisis, Themistoklis; Schwarz, Jan; Balles, Miriam; Kretschmer, Maibritt; Nemethova, Maria; Chait, Remy; Hauschild, Robert; Lange, Janina; Guet, Calin; Sixt, Michael und Zahler, Stefan (2021): Sequential and Switchable Patterning for Studying Cellular Processes under Spatiotemporal Control. In: ACS Applied Materials & Interfaces, Bd. 13, Nr. 30: S. 35545-35560

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Buchbeitrag

Kandil, Rima; Xie, Yuran; Mehta, Aditi und Merkel, Olivia (2020): A Method for Targeted Nonviral siRNA Delivery in Cancer and Inflammatory Diseases. In: Jain, Kewal K. (Hrsg.): Drug Delivery Systems. Methods in molecular biology, Bd. 2059. S. 155-166

Maass, Gerd; Zatloukal, Kurt; Schmidt, Walter; Berger, M.; Cotten, Matt; Wagner, Ernst; Birnstiel, Max L. und Buschle, M. (1994): The generation of tumor vaccines by adenovirus-enhanced transfection of cytokine genes into tumor cells. In: Skouteris, George G. (Hrsg.): Liver carcinogenesis. Berlin u.a.: Springer. S. 467-479 [PDF, 1MB]

Merkel, Olivia M. ORCID logoORCID: https://orcid.org/0000-0002-4151-3916 und Mehta, Aditi (20. Oktober 2020): Characterization techniques for studying the properties of nanocarriers for systemic delivery. In: Systemic Delivery Technologies in Anti-Aging Medicine: Methods and Applications. Systemic Delivery Technologies in Anti-Aging Medicine: Methods and Applications, Bd. 13. Cham: Springer. S. 57-86 [PDF, 1MB]

Riedmayr, Lisa M. (2020): SMaRT for Therapeutic Purposes. In: Li, Hui und Elfman, Justin (Hrsg.): Chimeric RNA. Methods in molecular biology : Methods and Protocols, Bd. 2079. New York, NY: Springer Nature. S. 219-232

Konferenzbeitrag

Kölbel, J.; Anuschek, M. L.; Seifert, I.; Frieß, Wolfgang und Zeitler, J. A. (2021): Stability of Protein-Sugar Lyophilizates Investigated with Terahertz Spectroscopy. 45th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz), Buffalo, NY, USA, 8-13 Nov. 2020. In: 2020 45th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz), IEEE.

Kölbel, J.; Anuschek, M. L.; Stelzl, I.; Frieß, Wolfgang und Zeitler, J. A. (2022): The Role of Terahertz Dynamics in Solid-state Protein Formulations. 47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz), Delft, Netherlands, 28 August 2022 - 02 September 2022. In: 2022 47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz), Piscataway, NJ, USA: IEEE. S. 1-2

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