Phylloxanthobilins are Abundant Linear Tetrapyrroles from Chlorophyll Breakdown with Activities Against Cancer Cells

Karg, Cornelia A.; Wang, Pengyu; Kluibenschedl, Florian; Müller, Thomas; Allmendinger, Lars; Vollmar, Angelika M. and Moser, Simone (2020): Phylloxanthobilins are Abundant Linear Tetrapyrroles from Chlorophyll Breakdown with Activities Against Cancer Cells. In: European Journal of Organic Chemistry, Vol. 2020, No. 29: pp. 4499-4509

Abstract

The major chlorophyll catabolites are colorless phyllobilins with four deconjugated pyrrole units. Their yellow oxidation products, are getting more and more in the spotlight due to their interesting physicochemical properties and potential bioactivities. Although studies on physiologically relevant activities of phyllobilins are in early stages, it already becomes evident that when it comes to bioactivities, yellow beats colorless.

• Item Type: Journal article
• Faculties: Chemistry and Pharmacy > Department of Pharmacy
• Subjects: 500 Science > 540 Chemistry; 600 Technology > 610 Medicine and health
• ISSN: 1099-0690
• Language: English