Anzahl der Publikationen auf dieser Ebene: 764
Englisch
Adams, Friederike ORCID: https://orcid.org/0000-0002-4362-0387; Zimmermann, Christoph M.; Baldassi, Domizia; Pehl, Thomas M. ORCID: https://orcid.org/0000-0001-5930-8091; Weingarten, Philipp; Kachel, Iris; Kränzlein, Moritz ORCID: https://orcid.org/0000-0001-9851-0735; Jürgens, David C.; Braubach, Peter ORCID: https://orcid.org/0000-0003-3673-7779; Alexopoulos, Ioannis ORCID: https://orcid.org/0000-0002-5601-2831; Wygrecka, Malgorzata ORCID: https://orcid.org/0000-0002-3656-2932 und Merkel, Olivia M. ORCID: https://orcid.org/0000-0002-4151-3916
(2023):
Pulmonary siRNA Delivery with Sophisticated Amphiphilic Poly(Spermine Acrylamides) for the Treatment of Lung Fibrosis.
In: Small
[PDF, 3MB]
Adouvi, Gustave; Isigkeit, Laura; Lopez-Garcia, Ursula; Chaikuad, Apirat; Marschner, Julian A.; Schubert-Zsilavecz, Manfred und Merk, Daniel
(2022):
Rational Design of a New RXR Agonist Scaffold Enabling Single-Subtype Preference for RXR alpha, RXR beta, and RXR gamma.
In: Journal of Medicinal Chemistry, Bd. 66, Nr. 1: S. 333-344
Alamri, Ahmad M.; Kang, Keunsoo; Groeneveld, Svenja; Wang, Weisheng; Zhong, Xiaogang; Kallakury, Bhaskar; Hennighausen, Lothar; Liu, Xuefeng und Furth, Priscilla A.
(2016):
Primary cancer cell culture: mammary-optimized vs conditional reprogramming.
In: Endocrine-Related Cancer, Bd. 23, Nr. 7: S. 535-554
Andima, Moses; Costabile, Gabriella; Isert, Lorenz; Ndakala, Albert J.; Derese, Solomon und Merkel, Olivia M.
(2018):
Evaluation of beta-Sitosterol Loaded PLGA and PEG-PLA Nanoparticles for Effective Treatment of Breast Cancer: Preparation, Physicochemical Characterization, and Antitumor Activity.
In: Pharmaceutics, Bd. 10, Nr. 4, 232
[PDF, 3MB]
Arango-Gonzalez, Blanca; Trifunović, Dragana; Sahaboglu, Ayse; Kranz, Katharina; Michalakis, Stylianos; Farinelli, Pietro; Koch, Susanne; Koch, Fred; Cottet, Sandra; Janssen-Bienhold, Ulrike; Dedek, Karin; Biel, Martin; Zrenner, Eberhart; Euler, Thomas; Ekstrom, Per; Ueffing, Marius und Paquet-Durand, François
(2014):
Identification of a Common Non-Apoptotic Cell Death Mechanism in Hereditary Retinal Degeneration.
In: PLOS ONE
9(11), e112142
[PDF, 1MB]
Ardelt, Maximilian A.; Fröhlich, Thomas; Martini, Emanuele; Müller, Martin; Kanitz, Veronika; Atzberger, Carina; Cantonati, Petra; Messner, Martina; Posselt, Laura; Lehr, Thorsten; Wojtyniak, Jan-Georg; Ulrich, Melanie; Arnold, Georg J.; König, Lars; Parazzoli, Dario; Zahler, Stefan; Rothenfusser, Simon; Mayr, Doris; Gerbes, Alexander; Scita, Giorgio; Vollmar, Angelika M. und Pachmayr, Johanna
(2019):
Inhibition of Cyclin-Dependent Kinase 5: A Strategy to Improve Sorafenib Response in Hepatocellular Carcinoma Therapy.
In: Hepatology, Bd. 69, Nr. 1: S. 376-393
Arifi, Silvia; Zaienne, Daniel; Heering, Jan; Wein, Thomas; Zhubi, Rezart; Chaikuad, Apirat; Knapp, Stefan; Marschner, Julian A. und Merk, Daniel
(2022):
Fragment-based discovery of orphan nuclear receptor Nur77/NGFI-B ligands.
In: Bioorganic Chemistry, Bd. 129, 106164
Arlt, E.; Arndt, L.; Breit, A.; Wennemuth, G.; Biel, M.; Wahl, C.; Gudermann, T.; Klugbauer, N. und Boekhoff, I.
(2017):
Two-pore channel protein 1 contributes to NAADP triggered acrosome reaction in spermatozoa.
In: Reproduction in Domestic Animals, Bd. 52: S. 6-7
Arroyo-Araujo, Maria; Voelkl, Bernhard; Laloux, Clement; Novak, Janja; Koopmans, Bastijn; Waldron, Ann-Marie; Seiffert, Isabel; Stirling, Helen; Aulehner, Katharina; Janhunen, Sanna K.; Ramboz, Sylvie; Potschka, Heidrun; Holappa, Johanna; Fine, Tania; Loos, Maarten; Boulanger, Bruno; Wurbel, Hanno und Kas, Martien J.
(2022):
Systematic assessment of the replicability and generalizability of preclinical findings: Impact of protocol harmonization across laboratory sites.
In: PLOS Biology
20(11), e3001886
Auffenberg, Eva; Jurik, Angela; Mattusch, Corinna; Stoffel, Rainer; Genewsky, Andreas; Namendorf, Christian; Schmid, Roland M.; Rammes, Gerhard; Biel, Martin; Uhr, Manfred; Moosmang, Sven; Michalakis, Stylianos; Wotjak, Carsten T. und Thoeringer, Christoph K.
(2016):
Remote and reversible inhibition of neurons and circuits by small molecule induced potassium channel stabilization.
In: Scientific Reports, Bd. 6, 19293
[PDF, 977kB]
Badieyan, Zohreh Sadat; Berezhanskyy, Taras; Utzinger, Maximilian; Aneja, Manish Kumar; Emrich, Daniela; Erben, Reinhold; Schüler, Christiane; Altpeter, Philipp; Ferizi, Mehrije; Hasenpusch, Günther; Rudolph, Carsten und Plank, Christian
(2016):
Transcript-activated collagen matrix as sustained mRNA delivery system for bone regeneration.
In: Journal of Controlled Release, Bd. 239: S. 137-148
Baldassi, Domizia; Ambike, Shubhankar; Feuerherd, Martin; Cheng, Cho-Chin; Peeler, David J.; Feldmann, Daniel P.; Porras-Gonzalez, Diana Leidy; Wei, Xin; Keller, Lea-Adriana; Kneidinger, Nikolaus; Stoleriu, Mircea Gabriel; Popp, Andreas; Burgstaller, Gerald; Pun, Suzie H.; Michler, Thomas und Merkel, Olivia M.
(2022):
Inhibition of SARS-CoV-2 replication in the lung with siRNA/VIPER polyplexes.
In: Journal of Controlled Release, Bd. 345: S. 661-674
Balsevich, Georgia; Häusl, Alexander S.; Meyer, Carola W.; Karamihalev, Stoyo; Feng, Xixi; Poehlmann, Max L.; Dournes, Carine; Uribe-Marino, Andres; Santarelli, Sara; Labermaier, Christiana; Hafner, Kathrin; Mao, Tianqi; Breitsamer, Michaela; Theodoropoulou, Marily; Namendorf, Christian; Uhr, Manfred; Paez-Pereda, Marcelo; Winter, Gerhard; Hausch, Felix; Chen, Alon; Tschöp, Matthias H.; Rein, Theo; Gassen, Nils C. und Schmidt, Mathias V.
(2017):
Stress-responsive FKBP51 regulates AKT2-AS160 signaling and metabolic function.
In: Nature Communications, Bd. 8, 1725
[PDF, 1MB]
Bao, Xuanwen; Shi, Run; Zhang, Kai; Xin, Shan; Li, Xin; Zhao, Yanbo und Wang, Yanfang
(18. September 2019):
Immune Landscape of Invasive Ductal Carcinoma Tumor Microenvironment Identifies a Prognostic and Immunotherapeutically Relevant Gene Signature.
In: Frontiers in Oncology, Bd. 9, 903: S. 1-15
[PDF, 2MB]
Bartel, Karin; Pein, Helmut; Popper, Bastian; Schmitt, Sabine; Janaki-Raman, Sudha; Schulze, Almut; Lengauer, Florian; Koeberle, Andreas; Werz, Oliver; Zischka, Hans; Müller, Rolf; Vollmar, Angelika M. und Schwarzenberg, Karin von
(2019):
Connecting lysosomes and mitochondria - a novel role for lipid metabolism in cancer cell death.
In: Cell Communication and Signaling, Bd. 17, 87
Bartel, Karin; Winzi, Maria; Ulrich, Melanie; Koeberle, Andreas; Menche, Dirk; Werz, Oliver; Müller, Rolf; Guck, Jochen; Vollmar, Angelika M. und Schwarzenberg, Karin von
(2017):
V-ATPase inhibition increases cancer cell stiffness and blocks membrane related Ras signaling - a new option for HCC therapy.
In: Oncotarget, Bd. 8, Nr. 6: S. 9476-9487
Becirovic, Elvir; Böhm, Sybille; Nguyen, Ong N. P.; Riedmayr, Lisa M.; Hammelmann, Verena; Schön, Christian; Butz, Elisabeth S.; Wahl-Schott, Christian; Biel, Martin und Michalakis, Stylianos
(2016):
AAV Vectors for FRET-Based Analysis of Protein-Protein Interactions in Photoreceptor Outer Segments.
In: Frontiers in Neuroscience, Bd. 10, 356
[PDF, 3MB]
Becirovic, Elvir; Böhm, Sybille; Nguyen, Ong Nam Phuong; Riedmayr, Lisa Maria; Koch, Mirja Annika; Schulze, Elisabeth; Kohl, Susanne; Borsch, Oliver; Santos-Ferreira, Tiago; Ader, Marius; Michalakis, Stylianos und Biel, Martin
(2016):
In Vivo Analysis of Disease-Associated Point Mutations Unveils Profound Differences in mRNA Splicing of Peripherin-2 in Rod and Cone Photoreceptors.
In: PLOS Genetics
12(1), e1005811
[PDF, 8MB]
Beck, Simon; Henß, Lisa; Weidner, Tatjana; Herrmann, Jennifer; Müller, Rolf; Chao, Yu-Kai; Grimm, Christian; Weber, Christopher; Sliva, Katja und Schnierle, Barbara S.
(2016):
Identification of entry inhibitors of Ebola virus pseudotyped vectors from a myxobacterial compound library.
In: Antiviral Research, Bd. 132: S. 85-91
Bender, Julia; Engeholm, Maik; Ederer, Marion S.; Breu, Johannes; Moller, Thor C.; Michalakis, Stylianos; Rasko, Tamas; Wanker, Erich E.; Biel, Martin; Martinez, Karen L.; Wurst, Wolfgang und Deussing, Jan M.
(2015):
Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Clustering with MAGUKs Is Mediated via Its C-Terminal PDZ Binding Motif.
In: PLOS ONE
10(9), e0136768
[PDF, 20MB]
Berger, Simone; Levacic, Ana Krhac; Hörterer, Elisa; Wilk, Ulrich; Benli-Hoppe, Teoman; Wang, Yanfang; Öztürk, Özgür; Luo, Jie und Wagner, Ernst
(2021):
Optimizing pDNA Lipo-polyplexes: A Balancing Act between Stability and Cargo Release.
In: Biomacromolecules, Bd. 22, Nr. 3: S. 1282-1296
Blank, Thomas; Goldmann, Tobias; Koch, Mirja; Amann, Lukas; Schön, Christian; Bonin, Michael; Pang, Shengru; Prinz, Marco; Burnet, Michael; Wagner, Johanna E.; Biel, Martin und Michalakis, Stylianos
(2018):
Early Microglia Activation Precedes Photoreceptor Degeneration in a Mouse Model of CNGB1-Linked Retinitis Pigmentosa.
In: Frontiers in Immunology, Bd. 8, 1930
[PDF, 7MB]
Blassmann, Ute; Hope, William; Roehr, Anka C.; Frey, Otto R.; Vetter-Kerkhoff, Cornelia; Thon, Niklas; Briegel, Josef und Huge, Volker
(2019):
CSF penetration of vancomycin in critical care patients with proven or suspected ventriculitis: a prospective observational study.
In: Journal of Antimicrobial Chemotherapy, Bd. 74, Nr. 4: S. 991-996
Bluemel, Oliver; Pavlistic, Andraz; Likozar, Blaz; Rodrigues, Miguel A.; Geraldes, Vitor; Bechtold-Peters, Karoline und Friess, Wolfgang
(2022):
Computational fluid dynamic simulations of temperature, cryoconcentration, and stress time during large-scale freezing and thawing of monoclonal antibody solutions.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 177: S. 107-112
Bluemel, Oliver; Rodrigues, A. Miguel; Buecheler, W. Jakob; Geraldes, Vitor; Hoelzl, Georg; Hauptmann, Astrid; Bechtold-Peters, Karoline und Friess, Wolfgang
(2022):
Evaluation of Two Novel Scale-Down Devices for Testing Monoclonal Antibody Aggregation During Large-Scale Freezing.
In: Journal of Pharmaceutical Sciences, Bd. 111, Nr. 7: S. 1973-1983
Bluemel, Oliver; Buecheler, Jakob W.; Hauptmann, Astrid; Hoelzl, Georg; Bechtold-Peters, Karoline und Frieß, Wolfgang
(2021):
Scaling Down Large-Scale Thawing of Monoclonal Antibody Solutions: 3D Temperature Profiles, Changes in Concentration, and Density Gradients.
In: Pharmaceutical Research, Bd. 38, Nr. 11: S. 1977-1989
Bluemel, Oliver; Buecheler, Jakob W.; Hauptmann, Astrid; Hoelzl, Georg; Bechtold-Peters, Karoline und Frieß, Wolfgang
(2021):
Scaling Down Large-Scale Thawing of Monoclonal Antibody Solutions: 3D Temperature Profiles, Changes in Concentration, and Density Gradients.
In: Pharmaceutical research, Bd. 38, Nr. 11: S. 1977-1989
[PDF, 3MB]
Bluemel, Oliver; Buecheler, Jakob W.; Rodrigues, Miguel A.; Geraldes, Vitor; Hoelzl, Georg; Bechtold-Peters, Karoline und Friess, Wolfgang
(2020):
Cryoconcentration and 3D Temperature Profiles During Freezing of mAb Solutions in Large-Scale PET Bottles and a Novel Scale-Down Device.
In: Pharmaceutical Research, Bd. 37, Nr. 9, 179
Bobak, Nicole; Feliciangeli, Sylvain; Chen, Cheng-Chang; Ben Soussia, Ismail; Bittner, Stefan; Pagnotta, Sophie; Ruck, Tobias; Biel, Martin; Wahl-Schott, Christian; Grimm, Christian; Meuth, Sven G. und Lesage, Florian
(2017):
Recombinant tandem of pore-domains in a Weakly Inward rectifying K+ channel 2 (TWIK2) forms active lysosomal channels.
In: Scientific Reports, Bd. 7, 649
[PDF, 11MB]
Boehm, Sybille; Splith, Victoria; Riedmayr, Lisa Maria; Rotzer, Rene Dominik; Gasparoni, Gilles; Nordstroem, Karl J. V.; Wagner, Johanna Elisabeth; Hinrichsmeyer, Klara Sonnie; Walter, Joern; Wahl-Schott, Christian; Fenske, Stefanie; Biel, Martin; Michalakis, Stylianos und Becirovic, Elvir
(2020):
A gene therapy for inherited blindness using dCas9-VPR-mediated transcriptional activation.
In: Science Advances, Bd. 6, Nr. 34, eaba5614
Bohn, Torsten; de Lera, Angel R.; Landrier, Jean-Francois; Carlsen, Harald; Merk, Daniel; Todt, Tilman; Renaut, Jenny und Ruehl, Ralph
(2022):
State-of-the-art methodological investigation of carotenoid activity and metabolism - from organic synthesis via metabolism to biological activity - exemplified by a novel retinoid signalling pathway.
In: Food & Function, Bd. 14, Nr. 2: S. 621-638
Borland, Kayla; Diesend, Jan; Ito-Kureha, Taku; Heissmeyer, Vigo; Hammann, Christian; Buck, Amy H.; Michalakis, Stylianos und Kellner, Stefanie
(2019):
Production and Application of Stable Isotope-Labeled Internal Standards for RNA Modification Analysis.
In: Genes, Bd. 10, Nr. 1, 26
Borowiak, Malgorzata; Kuellmer, Florian; Gegenfurtner, Florian; Peil, Sebastian; Nasufovic, Veselin; Zahler, Stefan; Thorn-Seshold, Oliver; Trauner, Dirk und Arndt, Hans-Dieter
(2020):
Optical Manipulation of F-Actin with Photoswitchable Small Molecules.
In: Journal of the American Chemical Society, Bd. 142, Nr. 20: S. 9240-9249
Bouwknegt, Jonna; Wiersma, Sanne J.; Ortiz-Merino, Raul A.; Doornenbal, Eline S. R.; Buitenhuis, Petrik; Giera, Martin; Mueller, Christoph und Pronk, Jack T.
(2021):
A squalene-hopene cyclase in Schizosaccharomyces japonicus represents a eukaryotic adaptation to sterol-limited anaerobic environments.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 118, Nr. 32, e2105225118
Braig, S.; Wiedmann, R. M.; Liebl, J.; Singer, M.; Kubisch, R.; Schreiner, L.; Abhari, B. A.; Wagner, E.; Kazmaier, U.; Fulda, S. und Vollmar, Angelika M.
(2014):
Pretubulysin: a new option for the treatment of metastatic cancer.
In: Cell Death & Disease, Bd. 5, e1001
Braig, Simone; Schmidt, B. U. Sebastian; Stoiber, Katharina; Haendel, Chris; Moehn, Till; Werz, Oliver; Mueller, Rolf; Zahler, Stefan; Koeberle, Andreas; Kaes, Josef A. und Vollmar, Angelika M.
(2015):
Pharmacological targeting of membrane rigidity: implications on cancer cell migration and invasion.
In: New Journal of Physics, Bd. 17, 083007
[PDF, 1MB]
Bryce, Nicole S.; Failes, Tim W.; Stehn, Justine R.; Baker, Karen; Zahler, Stefan; Arzhaeva, Yulia; Bischof, Leanne; Lyons, Ciaran; Dedova, Irina; Arndt, Greg M.; Gaus, Katharina; Goult, Benjamin T.; Hardeman, Edna C.; Gunning, Peter W. und Lock, John G.
(2019):
High-Content Imaging of Unbiased Chemical Perturbations Reveals that the Phenotypic Plasticity of the Actin Cytoskeleton Is Constrained.
In: Cell Systems, Bd. 9, Nr. 5
Buchmann, Stefan; Sandmann, Gunther H.; Walz, Lars; Reichel, Thomas; Beitzel, Knut; Wexel, Gabriele; Tian, Weiwei; Battmann, Achim; Vogt, Stephan; Winter, Gerhard und Imhoff, Andreas B.
(2015):
Growth factor release by vesicular phospholipid gels: in-vitro results and application for rotator cuff repair in a rat model.
In: BMC Musculoskeletal Disorders
16:82
[PDF, 1MB]
Burkard, Markus; Kohl, Susanne; Kratzig, Timm; Tanimoto, Naoyuki; Brennenstuhl, Christina; Bausch, Anne E.; Junger, Katrin; Reuter, Peggy; Sothilingam, Vithiyanjali; Beck, Susanne C.; Huber, Gesine; Ding, Xi-Qin; Mayer, Anja K.; Baumann, Britta; Weisschuh, Nicole; Zobor, Ditta; Hahn, Gesa-Astrid; Kellner, Ulrich; Venturelli, Sascha; Becirovic, Elvir; Charbel Issa, Peter; Koenekoop, Robert K.; Rudolph, Gunther; Heckenlively, John; Sieving, Paul; Weleber, Richard G.; Hamel, Christian; Zong, Xiangang; Biel, Martin; Lukowski, Robert; Seeliger, Matthias W.; Michalakis, Stylianos; Wissinger, Bernd und Ruth, Peter
(2018):
Accessory heterozygous mutations in cone photoreceptor CNGA3 exacerbate CNG channel-associated retinopathy.
In: The Journal of Clinical Investigation, Bd. 128, Nr. 12: S. 5663-5675
Butler, Michael R.; Ma, Hongwei; Yang, Fan; Belcher, Joshua; Le, Yun-Zheng; Mikoshiba, Katsuhiko; Biel, Martin; Michalakis, Stylianos; Iuso, Anthony; Krizaj, David und Ding, Xi-Qin
(2017):
Endoplasmic reticulum (ER) Ca2+-channel activity contributes to ER stress and cone death in cyclic nucleotide-gated channel deficiency.
In: Journal of Biological Chemistry, Bd. 292, Nr. 27: S. 11189-11205
Böhm, Sybille; Riedmayr, Lisa M.; Nguyen, O. N. Phuong; Giessl, Andreas; Liebscher, Toni; Butz, Elisabeth S.; Schön, Christian; Michalakis, Stylianos; Wahl-Schott, Christian; Biel, Martin und Becirovic, Elvir
(2017):
Peripherin-2 and Rom-1 have opposing effects on rod outer segment targeting of retinitis pigmentosa-linked peripherin-2 mutants.
In: Scientific Reports, Bd. 7, 2321
[PDF, 3MB]
Büning, Hildegard; Fehse, Boris; Ivics, Zoltán; Kochanek, Stefan; Koehl, Ulrike; Kupatt, Christian; Mussolino, Claudio; Nettelbeck, Dirk M.; Schambach, Axel; Uckert, Wolfgang; Wagner, Ernst und Cathomen, Toni
(2021):
Gene Therapy “Made in Germany”: A Historical Perspective, Analysis of the Status Quo, and Recommendations for Action by the German Society for Gene Therapy.
In: Human Gene Therapy, Bd. 32, Nr. 19-20: S. 987-996
Capeloa, Leon; Yazdi, Mina; Zhang, Heyang; Chen, Xiaobing; Nie, Yu; Wagner, Ernst; Lachelt, Ulrich und Barz, Matthias
(2022):
Cross-Linkable Polyion Complex Micelles from Polypept(o)ide-Based ABC-Triblock Copolymers for siRNA Delivery.
In: Macromolecular Rapid Communications, Bd. 43, Nr. 12, 2100698
Castonguay, Jan; Orth, Joachim H. C.; Müller, Thomas; Sleman, Faten; Grimm, Christian; Wahl-Schott, Christian; Biel, Martin; Mallmann, Robert Theodor; Bildl, Wolfgang; Schulte, Uwe und Klugbauer, Norbert
(2017):
The two-pore channel TPC1 is required for efficient protein processing through early and recycling endosomes.
In: Scientific Reports, Bd. 7, 10038
[PDF, 4MB]
Cattaneo, Giulia; Ubiali, Daniela; Calleri, Enrica; Rabuffetti, Marco; Höfner, Georg C.; Wanner, Klaus T.; Moraes, Marcela C. de; Martinelli, Leonardo K. B.; Santiago Santos, Diógenes; Speranza, Giovanna und Massolini, Gabriella
(2016):
Development, validation and application of a 96-well enzymatic assay based on LC-ESI-MS/MS quantification for the screening of selective inhibitors against Mycobacterium tuberculosis purine nucleoside phosphorylase.
In: Analytica Chimica Acta, Bd. 943: S. 89-97
Chao, Yu-Kai; Schludi, Verena; Chen, Cheng-Chang; Butz, Elisabeth; Nguyen, O. N. Phuong; Müller, Martin; Krüger, Jens; Kammerbauer, Claudia; Ben-Johny, Manu; Vollmar, Angelika M.; Berking, Carola; Biel, Martin; Wahl-Schott, Christian A. und Grimm, Christian
(2017):
TPC2 polymorphisms associated with a hair pigmentation phenotype in humans result in gain of channel function by independent mechanisms.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 114, Nr. 41, E8595-E8602
Chatzopoulou, E. I.; Raharja-Liu, P.; Murschhauser, A.; Sekhavati, F.; Buggenthin, F.; Vollmar, A. M.; Marr, C. und Rädler, Joachim O.
(2018):
A single-cell micro-trench platform for automatic monitoring of cell division and apoptosis after chemotherapeutic drug administration.
In: Scientific Reports, Bd. 8, 18042
[PDF, 1MB]
Chen, Cheng; Liu, Li; Shu, Ya-Qiao; Jing, Ping; Lu, Yun; Zhang, Xiao-Xue; Zong, Xian-Gang; Guo, Lian-Jun und Li, Chang-Jun
(2020):
Blockade of HCN2 Channels Provides Neuroprotection Against Ischemic Injury via Accelerating Autophagic Degradation in Hippocampal Neurons.
In: Neuroscience Bulletin, Bd. 36, Nr. 8: S. 875-894
Chen, Cheng-Chang; Butz, Elisabeth S.; Chao, Yu-Kai; Grishchuk, Yulia; Becker, Lars; Heller, Stefan; Slaugenhaupt, Susan A.; Biel, Martin; Wahl-Schott, Christian und Grimm, Christian
(2017):
Small Molecules for Early Endosome-Specific Patch Clamping.
In: Cell Chemical Biology, Bd. 24, Nr. 7: S. 907-916
Chen, Cheng-Chang; Cang, Chunlei; Fenske, Stefanie; Butz, Elisabeth; Chao, Yu-Kai; Biel, Martin; Ren, Dejian; Wahl-Schott, Christian und Grimm, Christian
(2017):
Patch-clamp technique to characterize ion channels in enlarged individual endolysosomes.
In: Nature Protocols, Bd. 12, Nr. 8: S. 1639-1658
Chen, Cheng-Chang; Keller, Marco; Hess, Martin; Schiffmann, Raphael; Urban, Nicole; Wolfgardt, Annette; Schaefer, Michael; Bracher, Franz; Biel, Martin; Wahl-Schott, Christian und Grimm, Christian
(2014):
A small molecule restores function to TRPML1 mutant isoforms responsible for mucolipidosis type IV.
In: Nature Communications, Bd. 5, 4681
[PDF, 1MB]
Choi, Jae Eun; Verhaegen, Monique E.; Yazdani, Sahr; Malik, Rohit; Harms, Paul W.; Mangelberger, Doris; Tien, Jean; Cao, Xuhong; Wang, Yuping; Cieslik, Marcin; Gurkan, Jonathan; Yazdani, Mishaal; Jing, Xiaojun; Juckette, Kristin; Su, Fengyun; Wang, Rui; Zhou, Bing; Apel, Ingrid J.; Wang, Shaomeng; Dlugosz, Andrzej A. und Chinnaiyan, Arul M.
(2019):
Characterizing the Therapeutic Potential of a Potent BET Degrader in Merkel Cell Carcinoma.
In: Neoplasia, Bd. 21, Nr. 3: S. 322-330
Conte, Gemma; Costabile, Gabriella; Baldassi, Domizia; Rondelli, Valeria; Bassi, Rosaria; Colombo, Diego; Linardos, Giulia; Fiscarelli, Ersilia V.; Sorrentino, Raffaella; Miro, Agnese; Quaglia, Fabiana; Brocca, Paola; D'Angelo, Ivana; Merkel, Olivia M. und Ungaro, Francesca
(2022):
Hybrid Lipid/Polymer Nanoparticles to Tackle the Cystic Fibrosis Mucus Barrier in siRNA Delivery to the Lungs: Does PEGylation Make the Difference?
In: ACS Applied Materials & Interfaces, Bd. 14, Nr. 6: S. 7565-7578
Corvaglia, Valentina; Carbajo, Daniel; Prabhakaran, Panchami; Ziach, Krzysztof; Mandal, Pradeep Kumar; Dos Santos, Victor; Legeay, Carole; Vogel, Rachel; Parissi, Vincent; Pourquier, Philippe und Huc, Ivan
(2019):
Carboxylate-functionalized foldamer inhibitors of HIV-1 integrase and Topoisomerase 1: artificial analogues of DNA mimic proteins.
In: Nucleic Acids Research, Bd. 47, Nr. 11: S. 5511-5521
Costabile, Gabriella; Gasteyer, Kathrin I.; Nadithe, Venkatereddy; Denburgh, Katherine van; Lin, Qian; Sharma, Shiv; Reineke, Joshua J.; Firestine, Steven M. und Merkel, Olivia M.
(2018):
Physicochemical and In Vitro Evaluation of Drug Delivery of an Antibacterial Synthetic Benzophenone in Biodegradable PLGA Nanoparticles.
In: Aaps Pharmscitech, Bd. 19, Nr. 8: S. 3561-3570
Dahlem, Charlotte; Siow, Wei Xiong; Lopatniuk, Maria; Tse, William K. F.; Kessler, Sonja M.; Kirsch, Susanne H.; Hoppstaedter, Jessica; Vollmar, Angelika M.; Müller, Rolf; Luzhetskyy, Andriy; Bartel, Karin und Kiemer, Alexandra K.
(2020):
Thioholgamide A, a New Anti-Proliferative Anti-Tumor Agent, Modulates Macrophage Polarization and Metabolism.
In: Cancers, Bd. 12, Nr. 5, 1288
De Meyer, Laurens; Lammens, Joris; Vanbillemont, Brecht; Van Bockstal, Pieter Jan; Corver, Jos; Vervaet, Chris; Friess, Wolfgang und De Beer, Thomas
(2019):
Dual chamber cartridges in a continuous pharmaceutical freeze-drying concept: Determination of the optimal dynamic infrared heater temperature during primary drying.
In: International Journal of Pharmaceutics, Bd. 570, 118631
Decembrini, Sarah; Martin, Catherine; Sennlaub, Florian; Chemtob, Sylvain; Bie, Martin; Samardzija, Marijana; Moulin, Alexandre; Behar-Cohen, Francine und Arsenijevic, Yvan
(2017):
Cone Genesis Tracing by the Chrnb4-EGFP Mouse Line: Evidences of Cellular Material Fusion after Cone Precursor Transplantation.
In: Molecular therapy, Bd. 25, Nr. 3: S. 634-653
Deglmann, Claus J.; Blazkow-Schmalzbauer, Katarzyna; Moorkamp, Sarah; Wallmichrath, Jens; Giunta, Riccardo E.; Rogach, Andrey L.; Wagner, Ernst; Baumeister, Rüdiger G. und Ogris, Manfred
(2018):
In vivo tracking of adipose tissue grafts with cadmium-tel-luride quantum dots.
In: Archives of Plastic Surgery-Aps, Bd. 45, Nr. 2: S. 111-117
[PDF, 1MB]
Deglmann, Claus J.; Błażków-Schmalzbauer, Katarzyna; Moorkamp, Sarah; Susha, Andrei S.; Herrler, Tanja; Giunta, Riccardo E.; Wagner, Ernst; Rogach, Andrey L.; Baumeister, Ruediger G. und Ogris, Manfred
(2017):
Cadmium Telluride Quantum Dots as a Fluorescence Marker for Adipose Tissue Grafts.
In: Annals of Plastic Surgery, Bd. 78, Nr. 2: S. 217-222
[PDF, 586kB]
Dekel, Noa; Eisenberg-Domovich, Yael; Karlas, Alexander; Meyer, Thomas F.; Bracher, Franz; Lebendiker, Mario; Danieli, Tsafi und Livnah, Oded
(2020):
Expression, purification and crystallization of CLK1 kinase - A potential target for antiviral therapy.
In: Protein Expression and Purification, Bd. 176, 105742
Dengler, Sebastian ORCID: https://orcid.org/0000-0002-0770-0267; Howard, Ryan T.; Morozov, Vasily; Tsiamantas, Christos ORCID: https://orcid.org/0000-0002-9326-7892; Huang, Wei‐En; Liu, Zhiwei; Dobrzanski, Christopher; Pophristic, Vojislava; Brameyer, Sophie; Douat, Céline ORCID: https://orcid.org/0000-0003-2678-1047; Suga, Hiroaki ORCID: https://orcid.org/0000-0002-5298-9186 und Huc, Ivan ORCID: https://orcid.org/0000-0001-7036-9696
(2023):
Display Selection of a Hybrid Foldamer–Peptide Macrocycle.
In: Angewandte Chemie International Edition, Bd. 62, Nr. 46
[PDF, 1MB]
Devaux, Floriane; Li, Xuesong; Sluysmans, Damien; Maurizot, Victor; Bakalis, Evangelos; Zerbetto, Francesco; Huc, Ivan und Duwez, Anne-Sophie
(2021):
Single-molecule mechanics of synthetic aromatic amide helices: Ultrafast and robust non-dissipative winding.
In: Chem, Bd. 7, Nr. 5
Dobersch, Stephanie; Rubio, Karla; Singh, Indrabahadur; Guenther, Stefan; Graumann, Johannes; Cordero, Julio; Castillo-Negrete, Rafael; Huynh, Minh Bao; Mehta, Aditi; Braubach, Peter; Cabrera-Fuentes, Hector; Bernhagen, Jürgen; Chao, Cho-Ming; Bellusci, Saverio; Guenther, Andreas; Preissner, Klaus T.; Kugel, Sita; Dobreva, Gergana; Wygrecka, Malgorzata; Braun, Thomas; Papy-Garcia, Dulce und Barreto, Guillermo
(2021):
Positioning of nucleosomes containing gamma-H2AX precedes active DNA demethylation and transcription initiation.
In: Nature Communications, Bd. 12, Nr. 1, 1072
[PDF, 3MB]
Domnowski, Martin; Lo Presti, Ken; Binder, Jonas; Reindl, Josef; Lehmann, Lucille; Kummer, Felix; Wolber, Meike; Satzger, Marion; Dehling, Marco; Jaehrling, Jan und Frieß, Wolfgang
(2021):
Generation of mAb Variants with Less Attractive Self-Interaction but Preserved Target Binding by Well-Directed Mutation.
In: Molecular Pharmaceutics, Bd. 18, Nr. 1: S. 236-245
Domnowski, Martin; Maruno, Takahiro; Enomoto, Kanta; Kummer, Felix; Kulakova, Alina; Harris, Pernille; Uchiyama, Susumu; Jaehrling, Jan und Friess, Wolfgang
(2021):
A Multi-Method Approach to Assess the Self-Interaction Behavior of Infliximab.
In: Journal of Pharmaceutical Sciences, Bd. 110, Nr. 5: S. 1979-1988
Dussmann, Philipp; Pagel, Judith I.; Vogel, Sabina; Magnusson, Terese; Zimmermann, Rene; Wagner, Ernst; Schaper, Wolfgang; Ogris, Manfred und Deindl, Elisabeth
(2011):
Live in vivo imaging of Egr-1 promoter activity during neonatal development, liver regeneration and wound healing.
In: BMC Developmental Biology
11:28
[PDF, 2MB]
Ehrler, Johanna H. M.; Brunst, Steffen; Tjaden, Amelie; Kilu, Whitney; Heering, Jan; Hernandez-Olmos, Victor; Krommes, Andre; Kramer, Jan S.; Steinhilber, Dieter; Schubert-Zsilavecz, Manfred; Müller, Susanne; Merk, Daniel und Proschak, Ewgenij
(2022):
Compilation and evaluation of a fatty acid mimetics screening library.
In: Biochemical Pharmacology, Bd. 204, 115191
Engert, Julia; Anamur, Cihad; Engelke, Laura; Fellner, Christian; Lell, Peter; Henke, Stefan; Stadler, Julia; Zoels, Susanne; Ritzmann, Mathias und Winter, Gerhard
(2018):
A pilot study using a novel pyrotechnically driven prototype applicator for epidermal powder immunization in piglets.
In: International Journal of Pharmaceutics, Bd. 545, Nr. 1-2: S. 215-228
Esfandyari, Dena; Idrissou, Bio Maria Gheo; Hennis, Konstantin; Avramopoulos, Petros; Dueck, Anne; El-Battrawy, Ibrahim; Grueter, Laurenz; Meier, Melanie Annemarie; Naeger, Anna Christina; Ramanujam, Deepak; Dorn, Tatjana; Meitinger, Thomas; Hagl, Christian; Milting, Hendrik; Borggrefe, Martin; Fenske, Stefanie; Biel, Martin; Dendorfer, Andreas; Sassi, Yassine; Moretti, Alessandra und Engelhardt, Stefan
(2022):
MicroRNA-365 regulates human cardiac action potential duration.
In: Nature Communications, Bd. 13, Nr. 1, 220
Falk, Nathalie; Kessler, Kristin; Schramm, Sinja-Fee; Boldt, Karsten; Becirovic, Elvir; Michalakis, Stylianos; Regus-Leidig, Hanna; Noegel, Angelika A.; Ueffing, Marius; Thiel, Christian T.; Roepman, Ronald; Brandstaetter, Johann Helmut und Giessl, Andreas
(2018):
Functional analyses of Pericentrin and Syne-2 interaction in ciliogenesis.
In: Journal of Cell Science, Bd. 131, Nr. 16
Fanter, Lena; Müller, Christoph; Schepmann, Dirk; Bracher, Franz und Wünsch, Bernhard
(2017):
Chiral-pool synthesis of 1,2,4-trisubstituted 1,4-diazepanes as novel sigma(1) receptor ligands.
In: Bioorganic & Medicinal Chemistry, Bd. 25, Nr. 17: S. 4778-4799
Farias Vercoza, Brunno Renato; Prado Godinho, Joseane Lima; Teixeira de Macedo-Silva, Sara; Huber, Kilian; Bracher, Franz; Souza, Wanderley de und Fernandes Rodrigues, Juliany Cola
(2017):
KH-TFMDI, a novel sirtuin inhibitor, alters the cytoskeleton and mitochondrial metabolism promoting cell death in Leishmania amazonensis.
In: Apoptosis, Bd. 22, Nr. 9: S. 1169-1188
Farinelli, P.; Perera, A.; Arango-Gonzalez, B.; Trifunovic, D.; Wagner, M.; Carell, T.; Biel, M.; Zrenner, E.; Michalakis, S.; Paquet-Durand, F. und Ekström, P. A. R.
(2014):
DNA methylation and differential gene regulation in photoreceptor cell death.
In: Cell Death & Disease, Bd. 5, e1558
[PDF, 5MB]
Faudone, Giuseppe; Kilu, Whitney; Ni, Xiaomin; Chaikuad, Apirat; Sreeramulu, Sridhar; Heitel, Pascal; Schwalbe, Harald; Knapp, Stefan; Schubert-Zsilavecz, Manfred; Heering, Jan und Merk, Daniel
(2021):
The Transcriptional Repressor Orphan Nuclear Receptor TLX Is Responsive to Xanthines.
In: ACS Pharmacology & Translational Science, Bd. 4, Nr. 6: S. 1794-1807
Felber, Jan G.; Poczka, Lena; Scholzen, Karoline C.; Zeisel, Lukas; Maier, Martin S.; Busker, Sander; Theisen, Ulrike; Brandstädter, Christina; Becker, Katja; Arnér, Elias S. J.; Thorn-Seshold, Julia und Thorn-Seshold, Oliver
(1. April 2022):
Cyclic 5-membered disulfides are not selective substrates of thioredoxin reductase, but are opened nonspecifically.
In: Nature Communications, Bd. 13
[PDF, 2MB]
Feldmann, Daniel P.; Cheng, Yilong; Kandil, Rima; Xie, Yuran; Mohammadi, Mariam; Harz, Hartmann; Sharma, Akhil; Peeler, David J.; Moszczynska, Anna; Leonhardt, Heinrich; Pun, Suzie H. und Merkel, Olivia M.
(2018):
In vitro and in vivo delivery of siRNA via VIPER polymer system to lung cells.
In: Journal of Controlled Release, Bd. 276: S. 50-58
Fenske, Stefanie; Hennis, Konstantin; Roetzer, Rene D.; Brox, Verena F.; Becirovic, Elvir; Scharr, Andreas; Gruner, Christian; Ziegler, Tilman; Mehlfeld, Verena; Brennan, Jaclyn; Efimov, Igor R.; Pauza, Audrys G.; Moser, Markus; Wotjak, Carsten T.; Kupatt, Christian; Goenner, Rasmus; Zhang, Rai; Zhang, Henggui; Zong, Xiangang; Biel, Martin und Wahl-Schott, Christian
(2020):
cAMP-dependent regulation of HCN4 controls the tonic entrainment process in sinoatrial node pacemaker cells.
In: Nature Communications, Bd. 11, Nr. 1, 5555
[PDF, 10MB]
Fenske, Stefanie; Pröbstle, Rasmus; Auer, Franziska; Hassan, Sami; Marks, Vanessa; Pauza, Danius H.; Biel, Martin und Wahl-Schott, Christian
(2016):
Comprehensive multilevel in vivo and in vitro analysis of heart rate fluctuations in mice by ECG telemetry and electrophysiology.
In: Nature Protocols, Bd. 11, Nr. 1: S. 61-86
Fernandez, Belen; Olmedo, Pablo; Gil, Fernando; Fdez, Elena; Naaldijk, Yahaira; Rivero-Rios, Pilar; Bracher, Franz; Grimm, Christian; Churchill, Grant C. und Hilfiker, Sabine
(2022):
Iron-induced cytotoxicity mediated by endolysosomal TRPML1 channels is reverted by TFEB.
In: Cell Death & Disease, Bd. 13, Nr. 12, 1047
Fischer, M. Dominik; Wilhelm, Barbara; Michalakis, Stylianos; Zobor, Ditta; Kohl, Susanne; Seeliger, Matthias; Zrenner, Eberhart; Ueffing, Marius; Wissinger, Bernd; Biel, Martin und Bartz-Schmidt, Karl Ulrich
(2016):
Successful delivery of rAAV8.CNGA3 in a patient with CNGA3 achromatopsia.
In: Investigative Ophthalmology & Visual Science, Bd. 57, Nr. 12
Foerster, F.; Braig, S.; Moser, C.; Kubisch, R.; Busse, J.; Wagner, E.; Schmoeckel, E.; Mayr, D.; Schmitt, S.; Huettel, S.; Zischka, H.; Mueller, R. und Vollmar, Angelika M.
(2014):
Targeting the actin cytoskeleton: selective antitumor action via trapping PKCε.
In: Cell Death & Disease, Bd. 5, e1398
[PDF, 3MB]
Frank, James A.; Antonini, Marc-Joseph; Chiang, Po-Han; Canales, Andres; Konrad, David B.; Garwood, Indie C.; Rajic, Gabriela; Koehler, Florian; Fink, Yoel und Anikeeva, Polina
(2020):
In Vivo Photopharmacology Enabled by Multifunctional Fibers.
In: ACS Chemical Neuroscience, Bd. 11, Nr. 22: S. 3802-3813
Fuchs, Simone; Bischoff, Iris; Willer, Elisabeth A.; Bräutigam, Jacqueline; Bubik, Martin F.; Erdelmeier, Clemens A. J.; Koch, Egon; Faleschini, Maria T.; Mieri, Maria de; Bauhart, Milena; Zahler, Stefan; Hensel, Andreas; Hamburger, Matthias; Potterat, Olivier und Fürst, Robert
(2017):
The Dual Edema-Preventing Molecular Mechanism of the Crataegus Extract WS 1442 Can Be Assigned to Distinct Phytochemical Fractions.
In: Planta Medica, Bd. 83, Nr. 8: S. 701-709
Fuchs, Simone; Hsieh, Louise T.; Saarberg, Werner; Erdelmeier, Clemens A. J.; Wichelhaus, Thomas A.; Schaefer, Liliana; Koch, Egon und Fuerst, Robert
(2015):
Haemanthus coccineus extract and its main bioactive component narciclasine display profound anti-inflammatory activities in vitro and in vivo.
In: Journal of Cellular and Molecular Medicine, Bd. 19, Nr. 5: S. 1021-1032
[PDF, 718kB]
Funke, Stefanie; Matilainen, Julia; Nalenz, Heiko; Bechtold-Peters, Karoline; Mahler, Hanns-Christian; Vetter, Florian; Müller, Christoph; Bracher, Franz und Friess, Wolfgang
(2016):
Optimization of the bake-on siliconization of cartridges. Part II: Investigations into burn-in time and temperature.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 105: S. 209-222
Gabold, Bettina; Adams, Friederike; Brameyer, Sophie; Jung, Kirsten; Ried, Christian L.; Merdan, Thomas und Merkel, Olivia M.
(2022):
Transferrin-modified chitosan nanoparticles for targeted nose-to-brain delivery of proteins.
In: Drug Delivery and Translational Research, Bd. 13, Nr. 3: S. 822-838
[PDF, 2MB]
Gadelha, Ana Paula R.; Bravim, Barbara; Vidal, Juliana; Reignault, Lissa Catherine; Cosme, Bruno; Huber, Kilian; Bracher, Franz und de Souza, Wanderley
(2019):
Alterations on growth and cell organization of Giardia intestinalis trophozoites after treatment with KH-TFMDI, a novel class III histone deacetylase inhibitor.
In: International Journal of Medical Microbiology, Bd. 309, Nr. 2: S. 130-142
Gao, Li; Kraus, Yvonne; Stegner, Andrea; Wein, Thomas; Heise, Constanze; Brunn, Leonie von; Fajardo-Ruiz, Elena; Thorn-Seshold, Julia und Thorn-Seshold, Oliver
(2022):
Self-reporting styrylthiazolium photopharmaceuticals: mitochondrial localisation as well as SAR drive biological activity.
In: Organic & Biomolecular Chemistry, Bd. 20, Nr. 39: S. 7787-7794
Gao, Li ORCID: https://orcid.org/0000-0003-3963-4847; Meiring, Joyce C. M. ORCID: https://orcid.org/0000-0001-9166-5363; Heise, Constanze; Rai, Ankit; Müller‐Deku, Adrian ORCID: https://orcid.org/0000-0001-6050-2545; Akhmanova, Anna ORCID: https://orcid.org/0000-0002-9048-8614; Thorn‐Seshold, Julia ORCID: https://orcid.org/0000-0002-4879-4159 und Thorn‐Seshold, Oliver ORCID: https://orcid.org/0000-0003-3981-651X
(2022):
Photoswitchable Epothilone‐Based Microtubule Stabilisers Allow GFP‐Imaging‐Compatible, Optical Control over the Microtubule Cytoskeleton**.
In: Angewandte Chemie International Edition, Bd. 61, Nr. 10
[PDF, 7MB]
Gao, Li; Meiring, Joyce C. M.; Varady, Adam; Ruider, Iris E.; Heise, Constanze; Wranik, Maximilian; Velasco, Cecilia D.; Taylor, Jennifer A.; Terni, Beatrice; Weinert, Tobias; Standfuss, Jörg; Cabernard, Clemens C.; Llobet, Artur; Steinmetz, Michel O.; Bausch, Andreas R.; Distel, Martin; Thorn-Seshold, Julia; Akhmanova, Anna und Thorn-Seshold, Oliver
(2022):
In Vivo Photocontrol of Microtubule Dynamics and Integrity, Migration and Mitosis, by the Potent GFP-Imaging-Compatible Photoswitchable Reagents SBTubA4P and SBTub2M.
In: Journal of the American Chemical Society, Bd. 144, Nr. 12: S. 5614-5628
Gegenfurtner, Florian A.; Jahn, Berenice; Wagner, Helga; Ziegenhain, Christoph; Enard, Wolfgang; Geistlinger, Ludwig; Rädler, Joachim O.; Vollmar, Angelika M. und Zahler, Stefan
(2018):
Micropatterning as a tool to identify regulatory triggers and kinetics of actin-mediated endothelial mechanosensing.
In: Journal of Cell Science, Bd. 131, Nr. 10
Gegenfurtner, Florian A.; Zisis, Themistoklis; Al Danaf, Nader; Schrimpf, Waldemar; Kliesmete, Zane; Ziegenhain, Christoph; Enard, Wolfgang; Kazmaier, Uli; Lamb, Don C.; Vollmar, Angelika M. und Zahler, Stefan
(2018):
Transcriptional effects of actin-binding compounds: the cytoplasm sets the tone.
In: Cellular and Molecular Life Sciences, Bd. 75, Nr. 24: S. 4539-4555
Gentiluomo, Lorenzo; Roessner, Dierk; Augustijn, Dillen; Svilenov, Hristo ORCID: https://orcid.org/0000-0001-5863-9569; Kulakova, Alina; Mahapatra, Sujata; Winter, Gerhard; Streicher, Werner; Rinnan, Asmund; Peters, Günther; Harris, Pernille und Friess, Wolfgang
(August 2019):
Application of interpretable artificial neural networks to early monoclonal antibodies development.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 141: S. 81-89
[PDF, 1MB]
Gerckens, Michael; Schorpp, Kenji; Pelizza, Francesco; Woegrath, Melanie; Reichau, Kora; Ma, Huilong; Dworsky, Armando-Marco; Sengupta, Arunima; Stoleriu, Mircea Gabriel; Heinzelmann, Katharina; Merl-Pham, Juliane; Irmler, Martin; Alsafadi, Hani N.; Trenkenschuh, Eduard; Sarnova, Lenka; Jirouskova, Marketa; Friess, Wolfgang; Hauck, Stefanie M.; Beckers, Johannes; Kneidinger, Nikolaus; Behr, Jürgen; Hilgendorff, Anne; Hadian, Kamyar; Lindner, Michael; Koenigshoff, Melanie; Eickelberg, Oliver; Gregor, Martin; Plettenburg, Oliver; Yildirim, Ali Oender und Burgstaller, Gerald
(2021):
Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics.
In: Science Advances, Bd. 7, Nr. 52, eabb3673
Germer, Janin; Lessl, Anna-Lina; Pöhmerer, Jana; Grau, Melina; Weidinger, Eric; Höhn, Miriam; Yazdi, Mina; Cappelluti, Martino Alfredo; Lombardo, Angelo; Lächelt, Ulrich und Wagner, Ernst ORCID: https://orcid.org/0000-0001-8413-0934
(2024):
Lipo-Xenopeptide Polyplexes for CRISPR/Cas9 based Gene editing at ultra-low dose.
In: Journal of Controlled Release, Bd. 370: S. 239-255
[PDF, 10MB]
Ghanawi, Hanaa; Hennlein, Luisa; Zare, Abdolhossein; Bader, Jakob; Salehi, Saeede; Hornburg, Daniel; Ji, Changhe; Sivadasan, Rajeeve; Drepper, Carsten; Meissner, Felix; Mann, Matthias; Jablonka, Sibylle; Briese, Michael und Sendtner, Michael
(2021):
Loss of full-length hnRNP R isoform impairs DNA damage response in motoneurons by inhibiting Yb1 recruitment to chromatin.
In: Nucleic Acids Research, Bd. 49, Nr. 21: S. 12284-12305
Glas, Carina; Naydenova, Eli; Lechner, Severin; Woessner, Nathalie; Yang, Liu; Dietschreit, Johannes C. B.; Sun, Hongyan; Jung, Manfred; Kuster, Bernhard; Ochsenfeld, Christian und Bracher, Franz
(2022):
Development of hetero-triaryls as a new chemotype for subtype-selective and potent Sirt5 inhibition.
In: European Journal of Medicinal Chemistry, Bd. 240, 114594
Glas, Carina; Dietschreit, Johannes C. B.; Woessner, Nathalie; Urban, Lars; Ghazy, Ehab; Sippl, Wolfgang; Jung, Manfred; Ochsenfeld, Christian und Bracher, Franz
(2020):
Identification of the subtype-selective Sirt5 inhibitor balsalazide through systematic SAR analysis and rationalization via theoretical investigations.
In: European Journal of Medicinal Chemistry, Bd. 206, 112676
Gleissner, Carolin M. -L.; Pyka, Carolin L.; Heydenreuter, Wolfgang; Gronauer, Thomas F.; Atzberger, Carina; Korotkov, Vadim S.; Cheng, Weiting; Hacker, Stephan M.; Vollmar, Angelika M.; Braig, Simone und Sieber, Stephan A.
(2019):
Neocarzilin A Is a Potent Inhibitor of Cancer Cell Motility Targeting VAT-1 Controlled Pathways.
In: ACS Central Science, Bd. 5, Nr. 7: S. 1170-1178
Grapentin, Christoph; Müller, Claudia; Kishore, Ravuri S. K.; Adler, Michael; ElBialy, Inas; Friess, Wolfgang; Huwyler, Jörg und Khan, Tarik A.
(2020):
Protein-Polydimethylsiloxane Particles in Liquid Vial Monoclonal Antibody Formulations Containing Poloxamer 188.
In: Journal of Pharmaceutical Sciences, Bd. 109, Nr. 8: S. 2393-2404
Grimm, Christian; Barben, Maya; Ail, Divya; Kast, Brigitt; Schori, Christian; Giger-Lange, Christina; Michalakis, Stylianos und Samardzija, Marijana
(2016):
Inactivation of Hif1a rescues rods and cones from degeneration induced by a chronic hypoxia-like response: HIF1A as therapeutic target in AMD?
In: Investigative Ophthalmology & Visual Science, Bd. 57, Nr. 12
Grimm, Christian; Holdt, Lesca M.; Chen, Cheng-Chang; Hassan, Sami; Müller, Christoph; Jörs, Simone; Cuny, Hartmut; Kissing, Sandra; Schröder, Bernd; Butz, Elisabeth; Northoff, Bernd; Castonguay, Jan; Luber, Christian A.; Moser, Markus; Spahn, Saskia; Luellmann-Rauch, Renate; Fendel, Christina; Klugbauer, Norbert; Griesbeck, Oliver; Haas, Albert; Mann, Matthias; Bracher, Franz; Teupser, Daniel; Saftig, Paul; Biel, Martin und Wahl-Schott, Christian
(2014):
High susceptibility to fatty liver disease in two-pore channel 2-deficient mice.
In: Nature Communications, Bd. 5, 4699
[PDF, 3MB]
Gronauer, Thomas F.; Mandl, Melanie M.; Lakemeyer, Markus; Hackl, Mathias W.; Messner, Martina; Korotkov, Vadim S.; Pachmayr, Johanna und Sieber, Stephan A.
(2018):
Design and synthesis of tailored human caseinolytic protease P inhibitors.
In: Chemical Communications, Bd. 54, Nr. 70: S. 9833-9836
Gryzlo, Beata; Zareba, Paula; Malawska, Katarzyna; Mazur, Gabriela; Rapacz, Anna; Latka, Kamil; Höfner, Georg C.; Latacz, Gniewomir; Bajda, Marek; Salat, Kinga; Wanner, Klaus T.; Malawska, Barbara und Kulig, Katarzyna
(2021):
Novel Functionalized Amino Acids as Inhibitors of GABA Transporters with Analgesic Activity.
In: ACS Chemical Neuroscience, Bd. 12, Nr. 16: S. 3073-3100
Guenther, Ilka; Rimbach, Gerald; Mack, Carina; Weinert, Christoph H.; Danylec, Nicolas; Lueersen, Kai; Birringer, Marc; Bracher, Franz; Soukup, Sebastian T.; Kulling, Sabine E. und Pallauf, Kathrin
(2020):
The Putative Caloric Restriction Mimetic Resveratrol has Moderate Impact on Insulin Sensitivity, Body Composition, and the Metabolome in Mice.
In: Molecular Nutrition & Food Research, Bd. 64, Nr. 6, 1901116
Gut, Fabian; Kaeshammer, Lisa; Lammens, Katja; Bartho, Joseph D.; Boggusch, Anna-Maria; Logt, Erik van de; Kessler, Brigitte und Hopfner, Karl-Peter
(2022):
Structural mechanism of endonucleolytic processing of blocked DNA ends and hairpins by Mre11-Rad50.
In: Molecular Cell, Bd. 82, Nr. 18: S. 3513-3522
Hammelmann, Verena; Stieglitz, Marc Sebastian; Huelle, Henrik; Le Meur, Karim; Kass, Jennifer; Bruemmer, Manuela; Gruner, Christian; Roetzer, Rene Dominik; Fenske, Stefanie; Hartmann, Jana; Zott, Benedikt; Luthi, Anita; Spahn, Saskia; Moser, Markus; Isbrandt, Dirk; Ludwig, Andreas; Konnerth, Arthur; Wahl-Schott, Christian und Biel, Martin
(2019):
Abolishing cAMP sensitivity in HCN2 pacemaker channels induces generalized seizures.
In: Jci Insight, Bd. 4, Nr. 9, e126418
Hartl, Natascha; Gabold, Bettina; Uhl, Philipp; Kromer, Adrian; Xiao, Ximian; Fricker, Gert; Mier, Walter; Liu, Runhui und Merkel, Olivia M. ORCID: https://orcid.org/0000-0002-4151-3916
(2024):
ApoE—functionalization of nanoparticles for targeted brain delivery—a feasible method for polyplexes?
In: Drug Delivery and Translational Research, Bd. 14, Nr. 6: S. 1660-1677
[PDF, 1MB]
Haryadi, Bernard Manuel; Hafner, Daniel; Amin, Ihsan; Schubel, Rene; Jordan, Rainer; Winter, Gerhard ORCID: https://orcid.org/0000-0002-7413-6627 und Engert, Julia
(September 2019):
Nonspherical Nanoparticle Shape Stability Is Affected by Complex Manufacturing Aspects: Its Implications for Drug Delivery and Targeting.
In: Advanced Healthcare Materials, Bd. 8, Nr. 18, 1900352
[PDF, 2MB]
Heering, Jan; Jores, Nathalie; Kilu, Whitney; Schallmayer, Espen; Peelen, Evelyn; Muehler, Andreas; Kohlhof, Hella; Vitt, Daniel; Linhard, Verena; Gande, Santosh L.; Chaikuad, Apirat; Sreeramulu, Sridhar; Schwalbe, Harald und Merk, Daniel
(2022):
Mechanistic Impact of Different Ligand Scaffolds on FXR Modulation Suggests Avenues to Selective Modulators.
In: ACS Chemical Biology, Bd. 17, Nr. 11: S. 3159-3168
Heller, Philipp; Hobernik, Dominika; Lächelt, Ulrich; Schinnerer, Meike; Weber, Benjamin; Schmidt, Manfred; Wagner, Ernst; Bros, Matthias und Barz, Matthias
(2017):
Combining reactive triblock copolymers with functional cross-linkers: A versatile pathway to disulfide stabilized-polyplex libraries and their application as pDNA vaccines.
In: Journal of Controlled Release, Bd. 258: S. 146-160
Hennis, Konstantin; Roetzer, Rene D.; Rilling, Julia; Wu, Yakun; Thalhammer, Stefan B.; Biel, Martin; Wahl-Schott, Christian und Fenske, Stefanie
(2022):
In vivo and ex vivo electrophysiological study of the mouse heart to characterize the cardiac conduction system, including atrial and ventricular vulnerability.
In: Nature Protocols, Bd. 17, Nr. 5: S. 1189-1222
Herrmann, Jennifer; Elnakady, Yasser A.; Wiedmann, Romina M.; Ullrich, Angelika; Rohde, Manfred; Kazmaier, Uli; Vollmar, Angelika M. und Müller, Rolf
(2012):
Pretubulysin: from hypothetical biosynthetic intermediate to potential lead in tumor therapy.
In: PLOS ONE
7(5), e37416
[PDF, 1MB]
Herrmann, Stefan; Rajab, Hamsa; Christ, Irina; Schirdewahn, Christoph; Höfler, Daniel; Fischer, Michael J. M.; Bruno, Ariane; Fenske, Stefanie; Gruner, Christian; Kramer, Felix; Wachsmann, Tassilo; Wahl-Schott, Christian; Stieber, Juliane; Biel, Martin und Ludwig, Andreas
(2017):
Protein kinase A regulates inflammatory pain sensitization by modulating HCN2 channel activity in nociceptive sensory neurons.
In: Pain, Bd. 158, Nr. 10: S. 2012-2024
Herzog, Julia; Ehrlich, Sandra M.; Pfitzer, Lisa; Liebl, Johanna; Fröhlich, Thomas; Arnold, Georg J.; Mikulits, Wolfgang; Haider, Christine; Vollmar, Angelika M. und Zahler, Stefan
(2016):
Cyclin-dependent kinase 5 stabilizes hypoxia-inducible factor-1 alpha: a novel approach for inhibiting angiogenesis in hepatocellular carcinoma.
In: Oncotarget, Bd. 7, Nr. 19: S. 27108-27121
Hesbacher, Sonja; Pfitzer, Lisa; Wiedorfer, Katharina; Angermeyer, Sabrina; Borst, Andreas; Haferkamp, Sebastian; Scholz, Claus-Jürgen; Wobser, Marion; Schrama, David und Houben, Roland
(2016):
RB1 is the crucial target of the Merkel cell polyomavirus Large T antigen in Merkel cell carcinoma cells.
In: Oncotarget, Bd. 7, Nr. 22: S. 32956-32968
Hirschberger, Kristin; Jarzebinska, Anita; Kessel, Eva; Kretzschmann, Verena; Aneja, Manish K.; Dohmen, Christian; Herrmann-Janson, Annika; Wagner, Ernst; Plank, Christian und Rudolph, Carsten
(2018):
Exploring Cytotoxic mRNAs as a Novel Class of Anti-cancer Biotherapeutics.
In: Molecular Therapy-Methods & Clinical Development, Bd. 8: S. 141-151
[PDF, 1MB]
Hoffmann, Eugenia; Jordan, Gregor; Lauer, Matthias; Ringler, Philippe; Kusznir, Eric A.; Rufer, Arne C.; Huber, Sylwia; Jochner, Anton; Winter, Gerhard und Staack, Roland F.
(2019):
Generation, Characterization, and Quantitative Bioanalysis of Drug/Anti-drug Antibody Immune Complexes to Facilitate Dedicated In Vivo Studies.
In: Pharmaceutical Research, Bd. 36, Nr. 9, UNSP 129
Holm, Regina; Schwiertz, David; Weber, Benjamin; Schultze, Jennifer; Kuhn, Jasmin; Koynov, Kaloian; Laechelt, Ulrich und Barz, Matthias
(2019):
Multifunctional Cationic PeptoStars as siRNA Carrier: Influence of Architecture and Histidine Modification on Knockdown Potential.
In: Macromolecular Bioscience, Bd. 20, Nr. 1, 1900152
Horn, Jacqueline; Jena, Sampeeti; Aksan, Alptekin und Friess, Wolfgang
(2019):
Freeze/thaw of IGG solutions.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 134: S. 185-189
Hu, Yudong; Mostert, Dietrich; Orgler, Christina; Andler, Oliver; Zischka, Hans; Kazmaier, Uli; Vollmar, Angelika M.; Braig, Simone; Sieber, Stephan A. ORCID: https://orcid.org/0000-0002-9400-906X und Zahler, Stefan ORCID: https://orcid.org/0000-0002-5140-7287
(2024):
Thermal Proteome Profiling Reveals Insight to Antiproliferative and Pro‐Apoptotic Effects of Lagunamide A in the Modulation of DNA Damage Repair.
In: ChemBioChem, Bd. 25, Nr. 13
[PDF, 2MB]
Hubler, Zita; Allimuthu, Dharmaraja; Bederman, Ilya; Elitt, Matthew S.; Madhavan, Mayur; Allan, Kevin C.; Shick, H. Elizabeth; Garrison, Eric; Karl, Molly T.; Factor, Daniel C.; Nevin, Zachary S.; Sax, Joel L.; Thompson, Matthew A.; Fedorov, Yuriy; Jin, Jing; Wilson, William K.; Giera, Martin; Bracher, Franz; Miller, Robert H.; Tesar, Paul J. und Adams, Drew J.
(2018):
Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination.
In: Nature, Bd. 560, Nr. 7718: S. 372-376
Ismail, Sherif; Flemming, Dirk; Thoms, Matthias; Gomes-Filho, Jose Vicente; Randau, Lennart; Beckmann, Roland und Hurt, Ed
(2022):
Emergence of the primordial pre-60S from the 90S pre-ribosome.
In: Cell Reports, Bd. 39, Nr. 1, 110640
Jiang, Qian; Yue, Dong; Nie, Yu; Xu, Xianghui; He, Yiyan; Zhang, Shiyong; Wagner, Ernst und Gu, Zhongwei
(2016):
Specially-Made Lipid-Based Assemblies for Improving Transmembrane Gene Delivery: Comparison of Basic Amino Acid Residue Rich Periphery.
In: Molecular Pharmaceutics, Bd. 13, Nr. 6: S. 1809-1821
Jimenez, Lucia; Silva, Andreia; Calissi, Giampaolo; Grenho, Ines; Monteiro, Rita; Mayoral-Varo, Victor; Blanco-Aparicio, Carmen; Pastor, Joaquin; Bustos, Victor; Bracher, Franz; Megias, Diego; Ferreira, Bibiana I. und Link, Wolfgang
(2022):
Screening Health-Promoting Compounds for Their Capacity to Induce the Activity of FOXO3.
In: Journals of Gerontology Series A: Biological Sciences and Medical Sciences, Bd. 77, Nr. 8: S. 1485-1493
Jin, Yao; Adams, Friederike; Moeller, Judith; Isert, Lorenz; Zimmermann, Christoph M. M.; Keul, David und Merkel, Olivia M. M.
(2022):
Synthesis and Application of Low Molecular Weight PEI-Based Copolymers for siRNA Delivery with Smart Polymer Blends.
In: Macromolecular Bioscience, Bd. 23, Nr. 2
[PDF, 2MB]
Junker, Julia; Chong, Isabelle; Kamp, Frits; Steiner, Harald; Giera, Martin; Müller, Christoph und Bracher, Franz
(2019):
Comparison of Strategies for the Determination of Sterol Sulfates via GC-MS Leading to a Novel Deconjugation-Derivatization Protocol.
In: Molecules, Bd. 24, Nr. 13, 2353
Kaiser, Jesko; Gertzen, Christoph G. W.; Bernauer, Tamara; Hoefner, Georg; Niessen, Karin V.; Seeger, Thomas; Paintner, Franz F.; Wanner, Klaus T.; Worek, Franz; Thiermann, Horst und Gohlke, Holger
(2022):
A novel binding site in the nicotinic acetylcholine receptor for MB327 can explain its allosteric modulation relevant for organophosphorus-poisoning treatment.
In: Toxicology Letters, Bd. 373: S. 160-171
Kappler, Sarah; Karmann, Lisa; Prudel, Cynthia; Herrmann, Jennifer; Caddeu, Giulia; Müller, Rolf; Vollmar, Angelika M.; Zahler, Stefan und Kazmaier, Uli
(2018):
Synthesis and Biological Evaluation of Modified Miuraenamides.
In: European Journal of Organic Chemistry, Nr. 48: S. 6952-6965
Karg, Cornelia A.; Parrakova, Lucia; Fuchs, Dietmar; Schennach, Harald; Kräutler, Bernhard; Moser, Simone und Gostner, Johanna M.
(2022):
A Chlorophyll-Derived Phylloxanthobilin Is a Potent Antioxidant That Modulates Immunometabolism in Human PBMC.
In: Antioxidants, Bd. 11, Nr. 10
[PDF, 2MB]
Karg, Cornelia A.; Doppler, Christian; Schilling, Charlotte; Jakobs, Franziska; Dal Colle, Marlene C. S.; Frey, Nadine; Bernhard, David; Vollmar, Angelika M. und Moser, Simone
(2021):
A yellow chlorophyll catabolite in leaves of Urtica dioica L.: An overlooked phytochemical that contributes to health benefits of stinging nettle.
In: Food Chemistry, Bd. 359, 129906
Karg, Cornelia A.; Wang, Pengyu; Kluibenschedl, Florian; Müller, Thomas; Allmendinger, Lars; Vollmar, Angelika M. und Moser, Simone
(2020):
Phylloxanthobilins are Abundant Linear Tetrapyrroles from Chlorophyll Breakdown with Activities Against Cancer Cells.
In: European Journal of Organic Chemistry, Bd. 2020, Nr. 29: S. 4499-4509
[PDF, 2MB]
Karg, Cornelia A.; Wang, Shuaijun; Al Danaf, Nader; Pemberton, Ryan P.; Bernard, Denzil; Kretschmer, Maibritt; Schneider, Sabine; Zisis, Themistoklis; Vollmar, Angelika M.; Lamb, Don C.; Zahler, Stefan und Moser, Simone
(2021):
Tetrapyrrolic Pigments from Heme- and Chlorophyll Breakdown are Actin-Targeting Compounds.
In: Angewandte Chemie-International Edition, Bd. 60, Nr. 41: S. 22578-22584
Keil, Tobias W. M.; Zimmermann, Christoph; Baldassi, Domizia; Adams, Friederike; Frieß, Wolfgang; Mehta, Aditi und Merkel, Olivia M.
(2021):
Impact of Crystalline and Amorphous Matrices on Successful Spray Drying of siRNA Polyplexes for Inhalation of Nano-in-Microparticles.
In: Advanced Therapeutics, Bd. 4, Nr. 6, 2100073
Keller, Marco; Wolfgardt, Annette; Müller, Christoph; Wilcken, Rainer; Böckler, Frank M.; Oliaro-Bosso, Simonetta; Ferrante, Terenzio; Balliano, Gianni und Bracher, Franz
(2016):
Arylpiperidines as a new class of oxidosqualene cyclase inhibitors.
In: European Journal of Medicinal Chemistry, Bd. 109: S. 13-22
Kern, Sarah; Truebenbach, Ines; Hoehn, Miriam; Gorges, Jan; Kazmaier, Uli; Zahler, Stefan; Vollmar, Angelika M. und Wagner, Ernst
(2019):
Combined antitumoral effects of pretubulysin and methotrexate.
In: Pharmacology Research & Perspectives, Bd. 7, Nr. 1, UNSP e00460
Kern, Selina; Agarwal, Shruti; Huber, Kilian; Gehring, André P.; Strödke, Benjamin; Wirth, Christine C.; Brügl, Thomas; Abodo, Liliane Onambele; Dandekar, Thomas; Doerig, Christian; Fischer, Rainer; Tobin, Andrew B.; Alam, Mahmood M.; Bracher, Franz und Pradel, Gabriele
(2014):
Inhibition of the SR Protein-Phosphorylating CLK Kinases of Plasmodium falciparum Impairs Blood Stage Replication and Malaria Transmission.
In: PLOS ONE
9(9), e105732
[PDF, 3MB]
Khan, Arif O.; Becirovic, Elvir; Betz, Christian; Neuhaus, Christine; Altmüller, Janine; Riedmayr, Lisa Maria; Motameny, Susanne; Nürnberg, Gudrun; Nürnberg, Peter und Bolz, Hanno J.
(2017):
A deep intronic CLRN1 (USH3A) founder mutation generates an aberrant exon and underlies severe Usher syndrome on the Arabian Peninsula.
In: Scientific Reports, Bd. 7, 1411
[PDF, 2MB]
Kibat, Janek; Schirrmann, Thomas; Knape, Matthias J.; Helmsing, Saskia; Meier, Doris; Hust, Michael; Schröder, Christoph; Bertinetti, Daniela; Winter, Gerhard; Pardes, Khalid; Funk, Mia; Vala, Andrea; Giese, Nathalia; Herberg, Friedrich W.; Dübel, Stefan und Hoheisel, Jörg D.
(2016):
Utilisation of antibody microarrays for the selection of specific and informative antibodies from recombinant library binders of unknown quality.
In: New Biotechnology, Bd. 33, Nr. 5: S. 574-581
Kirmeier, Thomas; Gopalakrishnan, Ranganath; Gormanns, Vanessa; Werner, Anna M.; Cuboni, Serena; Rudolf, Georg C.; Höfner, Georg; Wanner, Klaus T.; Sieber, Stephan A.; Schmidt, Ulrike; Holsboer, Florian; Rein, Theo und Hausch, Felix
(2016):
Azidobupramine, an Antidepressant-Derived Bifunctional Neurotransmitter Transporter Ligand Allowing Covalent Labeling and Attachment of Fluorophores.
In: PLOS ONE
11(2), e0148608
[PDF, 768kB]
Kirsch, Volker C.; Orgler, Christina; Braig, Simone; Jeremias, Irmela; Auerbach, David; Müller, Rolf; Vollmar, Angelika M. und Sieber, Stephan A.
(2019):
The Cytotoxic Natural Product Vioprolide A Targets Nucleolar Protein 14, which is Essential for Ribosome Biogenesis.
In: Angewandte Chemie-International Edition, Bd. 59, Nr. 4: S. 1595-1600
Klein, D.; Kessler, W.; Pütz, C.; Semder, B.; Kirchinger, W.; Langsch, A.; Gries, W.; Otter, R.; Gallien, A. K. E.; Wurzenberger, X. und Filser, J. G.
(2018):
Single ingestion of di-(2-propylheptyl) phthalate (DPHP) by male volunteers: DPHP in blood and its metabolites in blood and urine.
In: Toxicology Letters, Bd. 294: S. 105-115
Klein, Philipp M.; Reinhard, Sören; Zhang, Wei; Klinker, Kristina; Kern, Sarah; Kessel, Eva; Barz, Matthias und Wagner, Ernst
(2017):
Novel Poly(Sarcosine) Click Shielding Agents Improve Circulation of Redox-Sensitive siRNA Lipo-Polyplexes In Vivo.
In: Molecular therapy, Bd. 25, Nr. 5: S. 144
Klein, Philipp Michael; Klinker, Kristina; Zhang, Wei; Kern, Sarah; Kessel, Eva; Wagner, Ernst und Barz, Matthias
(2018):
Efficient Shielding of Polyplexes Using Heterotelechelic Polysarcosines.
In: Polymers, Bd. 10, Nr. 6, 689
[PDF, 2MB]
Klier, John; Geis, Sabine; Steuer, Jeanette; Geh, Katharina; Reese, Sven; Fuchs, Sebastian; Müller, Ralf S.; Winter, Gerhard und Gehlen, Heidrun
(2018):
A comparison of nanoparticullate CpG immunotherapy with and without allergens in spontaneously equine asthma-affected horses, an animal model.
In: Immunity Inflammation and Disease, Bd. 6, Nr. 1: S. 81-96
Koch, Mirja; Scheel, Constanze; Ma, Hongwei; Yang, Fan; Stadlmeier, Michael; Glück, Andrea F.; Murenu, Elisa; Traube, Franziska R.; Carell, Thomas; Biel, Martin; Ding, Xi-Qin und Michalakis, Stylianos
(2021):
The cGMP-Dependent Protein Kinase 2 Contributes to Cone Photoreceptor Degeneration in the Cnga3-Deficient Mouse Model of Achromatopsia.
In: International Journal of Molecular Sciences, Bd. 22, Nr. 1, 52
Koczian, F.; Vomacka, J.; Vick, B.; Hettich, B.; Kazmaier, U.; Sieber, S.; Jeremias, I.; Vollmar, A. und Braig, S.
(2017):
Targeting the ER-Mitochondrial Interface of Cell Death Sensitizes Leukemia Cells towards Cytostatics.
In: Annals of Hematology, Bd. 96:
S73-S73
Koczian, Fabian; Naglo, Olga; Vomacka, Jan; Vick, Binje; Servatius, Phil; Zisis, Themistoklis; Hettich, Britta; Kazmaier, Uli; Sieber, Stephan A.; Jeremias, Irmela; Zahler, Stefan und Braig, Simone
(2019):
Targeting the endoplasmic reticulum-mitochondria interface sensitizes leukemia cells to cytostatics.
In: Haematologica, Bd. 104, Nr. 3: S. 546-555
Koehler, Victor; Gauthier, Maxime; Yao, Chenhao; Fournel-Marotte, Karine; Waeles, Philip; Kauffmann, Brice; Huc, Ivan; Coutrot, Frederic und Ferrand, Yann
(2022):
[3]Foldarotaxane-mediated synthesis of an improbable [2]rotaxane.
In: Chemical Communications, Bd. 58, Nr. 62: S. 8618-8621
Koerner, Andreas; Zhou, Enchen; Muller, Christoph; Mohammed, Yassene; Herceg, Sandra; Bracher, Franz; Rensen, Patrick C. N.; Wang, Yanan; Mirakaj, Valbona und Giera, Martin
(2019):
Inhibition of Delta 24-dehydrocholesterol reductase activates pro-resolving lipid mediator biosynthesis and inflammation resolution.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 116, Nr. 41: S. 20623-20634
Konrad, David B.; Ruehmann, Klaus-Peter; Ando, Hiroyasu; Hetzler, Belinda E.; Strassner, Nina; Houk, Kendall N.; Matsuura, Bryan S. und Trauner, Dirk
(2022):
A concise synthesis of tetrodotoxin.
In: Science, Bd. 377, Nr. 6604: S. 411-415
Kos, Petra; Lächelt, Ulrich; Herrmann, Annika; Mickler, Frauke M.; Krhač Levačić, Ana; Morys, Stephan; Bräuchle, Christoph und Wagner, Ernst
(2014):
Histidine-rich stabilized polyplexes for cMet-directed tumor-targeted gene transfer.
In: Nanoscale, Bd. 7, Nr. 12: S. 5350-5362
[PDF, 0B]
Kraus, Teresa; Lubitz, Annika; Schliesser, Ulrike; Giese, Christoph; Reuschel, Jana; Brecht, Rene; Engert, Julia und Winter, Gerhard
(2019):
Evaluation of a 3D Human Artificial Lymph Node as Test Model for the Assessment of Immunogenicity of Protein Aggregates.
In: Journal of Pharmaceutical Sciences, Bd. 108, Nr. 7: S. 2358-2366
Kraus, Yvonne; Glas, Carina; Melzer, Benedikt; Gao, Li; Heise, Constanze; Preusse, Monique; Ahlfeld, Julia; Bracher, Franz und Thorn-Seshold, Oliver
(2020):
Isoquinoline-based biaryls as a robust scaffold for microtubule inhibitors.
In: European Journal of Medicinal Chemistry, Bd. 186, 111865
Krauß, Jürgen; Müller, Christoph; Klimt, Monika; Valero, Leandro Jorquera; Martinez, Jose Francisco; Müller, Martin; Bartel, Karin; Binder, Ulrike und Bracher, Franz
(2021):
Synthesis, Biological Evaluation, and Structure-Activity Relationships of 4-Aminopiperidines as Novel Antifungal Agents Targeting Ergosterol Biosynthesis.
In: Molecules, Bd. 26, Nr. 23, 7208
Krishnathas, G. Melissa; Strödke, Benjamin; Mittmann, Laura; Zech, Thomas; Berger, Lena M.; Reichel, Christoph A.; Rösser, Silvia; Schmid, Tobias; Knapp, Stefan; Müller, Susanne; Bracher, Franz; Fürst, Robert und Bischoff-Kont, Iris
(2021):
C81-evoked inhibition of the TNFR1-NF kappa B pathway during inflammatory processes for stabilization of the impaired vascular endothelial barrier for leukocytes.
In: Faseb Journal, Bd. 35, Nr. 6, e21656
Kröger, Julia; Podjaski, Filip; Savasci, Gökcen; Moudrakovski, Igor; Jiménez-Solano, Alberto; Terban, Maxwell W.; Bette, Sebastian; Duppel, Viola; Joos, Markus; Senocrate, Alessandro; Dinnebier, Robert; Ochsenfeld, Christian und Lotsch, Bettina V.
(2022):
Conductivity Mechanism in Ionic 2D Carbon Nitrides: From Hydrated Ion Motion to Enhanced Photocatalysis.
In: Advanced Materials, Bd. 34, Nr. 7, 2107061
Kuhn, Jasmin; Klein, Philipp M.; Danaf, Nader al; Nordin, Joel Z.; Reinhard, Sören; Loy, Dominik M.; Höhn, Miriam; Andaloussi, Samir el; Lamb, Don C.; Wagner, Ernst; Aoki, Yoshitsugu; Lehto, Taavi und Lächelt, Ulrich
(2019):
Supramolecular Assembly of Aminoethylene‐Lipopeptide PMO Conjugates into RNA Splice‐Switching Nanomicelles.
In: Advanced Functional Materials, Bd. 29, Nr. 48, 1906432
[PDF, 1MB]
Kuhn, Jasmin; Lin, Yi; Levacic, Ana Krhac; Al Danaf, Nader; Peng, Lun; Hoehn, Miriam; Lamb, Don C.; Wagner, Ernst und Laechelt, Ulrich
(2020):
Delivery of Cas9/sgRNA Ribonucleoprotein Complexes via Hydroxystearyl Oligoamino Amides.
In: Bioconjugate Chemistry, Bd. 31, Nr. 3: S. 729-742
Kulakova, Alina; Indrakumar, Sowmya; Sonderby, Pernille; Gentiluomo, Lorenzo; Streicher, Werner; Roessner, Dierk; Friess, Wolfgang; Peters, Guenther H. J. und Harris, Pernille
(2020):
Small angle X-ray scattering and molecular dynamic simulations provide molecular insight for stability of recombinant human transferrin.
In: Journal of Structural Biology-X, Bd. 4, 100017
Köhler, Bianca; Dubovik, Sviatlana; Hörterer, Elisa; Wilk, Ulrich; Stöckl, Jan Bernd; Tekarslan-Sahin, Hande; Ljepoja, Bojan; Paulitschke, Philipp; Fröhlich, Thomas; Wagner, Ernst und Roidl, Andreas
(2022):
Combating Drug Resistance by Exploiting miRNA-200c-Controlled Phase II Detoxification.
In: Cancers, Bd. 14, Nr. 22
[PDF, 4MB]
Kölbel, J.; Anuschek, M. L.; Seifert, I.; Frieß, Wolfgang und Zeitler, J. A.
(2021):
Stability of Protein-Sugar Lyophilizates Investigated with Terahertz Spectroscopy.
45th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz), Buffalo, NY, USA, 8-13 Nov. 2020.
In: 2020 45th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz),
IEEE.
Kölbel, J.; Anuschek, M. L.; Stelzl, I.; Frieß, Wolfgang und Zeitler, J. A.
(2022):
The Role of Terahertz Dynamics in Solid-state Protein Formulations.
47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz), Delft, Netherlands, 28 August 2022 - 02 September 2022.
In: 2022 47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz),
Piscataway, NJ, USA: IEEE. S. 1-2
Köse, Meryem; Schiedel, Anke C.; Bauer, Alexander Andreas; Poschenrieder, Hermann; Burbiel, Joachim C.; Akkinepally, Raghuram Rao; Stachef, Hans-Dietrich und Müller, Christa E.
(2016):
Focused screening to identify new adenosine kinase inhibitors.
In: Bioorganic & Medicinal Chemistry, Bd. 24, Nr. 21: S. 5127-5133
Küllmer, Florian; Vepřek, Nynke A.; Borowiak, Malgorzata; Nasufović, Veselin; Barutzki, Sebastian; Thorn-Seshold, Oliver; Arndt, Hans-Dieter und Trauner, Dirk
(2022):
Next Generation Opto-Jasplakinolides Enable Local Remodeling of Actin Networks.
In: Angewandte Chemie International Edition, Bd. 61, Nr. 48, e202210220
Labouta, Hagar I.; Langer, Robert; Cullis, Pieter R.; Merkel, Olivia M.; Prausnitz, Mark R.; Gomaa, Yasmine; Nogueira, Sara S. und Kumeria, Tushar
(2022):
Role of drug delivery technologies in the success of COVID-19 vaccines: a perspective.
In: Drug Delivery and Translational Research, Bd. 12, Nr. 11: S. 2581-2588
Laprell, Laura; Tochitsky, Ivan; Kaur, Kuldeep; Manookin, Michael B.; Stein, Marco; Barber, David M.; Schön, Christian; Michalakis, Stylianos; Biel, Martin; Kramer, Richard H.; Sumser, Martin P.; Trauner, Dirk und Gelder, Russell N. van
(2017):
Photopharmacological control of bipolar cells restores visual function in blind mice.
In: Journal of Clinical investigation, Bd. 127, Nr. 7: S. 2598-2611
Larkin, Caroline M.; Hante, Nadhim Kamil; Breen, Eamon P.; Tomaszewski, Krzysztof A.; Eisele, Simon; Radomski, Marek W.; Ryan, Thomas A. und Santos-Martinez, Maria-Jose
(2018):
Role of matrix metalloproteinases 2 and 9, toll-like receptor 4 and platelet-leukocyte aggregate formation in sepsis-associated thrombocytopenia.
In: PLOS One
13(5), e0196478
[PDF, 3MB]
Lau, Benjamin; Beine-Golovchuk, Olga; Kornprobst, Markus; Cheng, Jingdong; Kressler, Dieter; Jady, Beata; Kiss, Tamas; Beckmann, Roland und Hurt, Ed
(2022):
Cms1 coordinates stepwise local 90S pre-ribosome assembly with timely snR83 release.
In: Cell Reports, Bd. 41, Nr. 8, 111684
Lee, Myungeun; Rice-Boucher, Paul J.; Collins, Logan Thrasher; Wagner, Ernst; Aulisa, Lorenzo; Hughes, Jeffrey und Curiel, David T.
(2022):
A Novel Piggyback Strategy for mRNA Delivery Exploiting Adenovirus Entry Biology.
In: Viruses, Bd. 14, Nr. 10, 2169
Lee, Dian-Jang; He, Dongsheng; Kessel, Eva; Padari, Kärt; Kempter, Susanne; Lächelt, Ulrich; Rädler, Joachim O.; Pooga, Margus und Wagner, Ernst
(2016):
Tumoral gene silencing by receptor-targeted combinatorial siRNA polyplexes.
In: Journal of Controlled Release, Bd. 244: S. 280-291
Lee, Dian-Jang; Kessel, Eva; Edinger, Daniel; He, Dongsheng; Klein, Philipp M.; Voith von Voithenberg, Lena; Lamb, Don C.; Lächelt, Ulrich; Lehto, Taavi und Wagner, Ernst
(2016):
Dual antitumoral potency of EG5 siRNA nanoplexes armed with cytotoxic bifunctional glutamyl-methotrexate targeting ligand.
In: Biomaterials, Bd. 77: S. 98-110
Lee, Dian-Jang; Kessel, Eva; Lehto, Taavi; Liu, Xueying; Yoshinaga, Naoto; Padari, Kart; Chen, Ying-Chen; Kempter, Susanne; Uchida, Satoshi; Rädler, Joachim O.; Pooga, Margus; Sheu, Ming-Thau; Kataoka, Kazunori und Wagner, Ernst
(2017):
Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability for In Vivo Gene Silencing in Leukemia.
In: Bioconjugate Chemistry, Bd. 28, Nr. 9: S. 2393-2409
Leser, Charlotte; Keller, Marco; Gerndt, Susanne; Urban, Nicole; Chen, Cheng-Chang; Schaefer, Michael; Grimm, Christian und Bracher, Franz
(2021):
Chemical and pharmacological characterization of the TRPML calcium channel blockers ML-SI1 and ML-SI3.
In: European Journal of Medicinal Chemistry, Bd. 210, 112966
Li, Sihan; Ikeuchi, Ken; Kato, Misaki; Buschauer, Robert; Sugiyama, Takato; Adachi, Shungo; Kusano, Hideo; Natsume, Tohru; Berninghausen, Otto; Matsuo, Yoshitaka; Becker, Thomas; Beckmann, Roland und Inada, Toshifumi
(2022):
Sensing of individual stalled 80S ribosomes by Fap1 for nonfunctional rRNA turnover.
In: Molecular Cell, Bd. 82, Nr. 18, E8: S. 3424-3437
Li, Yanfen; Schoen, Christian; Chen, Cheng-Chang; Yang, Zhuo; Liegl, Raffael; Murenu, Elisa; Schworm, Benedikt; Klugbauer, Norbert; Grimm, Christian; Wahl-Schott, Christian; Michalakis, Stylianos und Biel, Martin
(2021):
TPC2 promotes choroidal angiogenesis and inflammation in a mouse model of neovascular age-related macular degeneration.
In: Life Science Alliance, Bd. 4, Nr. 8, e202101047
Liebl, Johanna; Zhang, Siwei; Moser, Markus; Agalarov, Yan; Demir, Cansaran Saygili; Hager, Bianca; Bibb, James A.; Adams, Ralf H.; Kiefer, Friedemann; Miura, Naoyuki; Petrova, Tatiana V.; Vollmar, Angelika M. und Zahler, Stefan
(2015):
Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2.
In: Nature Communications, Bd. 6, 7274
[PDF, 2MB]
Lin, Hsiao-Chun Amy; Dean-Ben, Xose Luis; Reiss, Michael; Schöttle, Verena; Wahl-Schott, Christian A.; Efimov, Igor R. und Razansky, Daniel
(2018):
Ultrafast Volumetric Optoacoustic Imaging of Whole Isolated Beating Mouse Heart.
In: Scientific Reports, Bd. 8, 14132
[PDF, 2MB]
Liu, Xiaowen; Zhang, Peng; He, Dongsheng; Rödl, Wolfgang; Preiß, Tobias; Rädler, Joachim O.; Wagner, Ernst und Lächelt, Ulrich
(2016):
pH-Reversible Cationic RNase A Conjugates for Enhanced Cellular Delivery and Tumor Cell Killing.
In: Biomacromolecules, Bd. 17, Nr. 1: S. 173-182
Ljepoja, Bojan; Schreiber, Christoph; Gegenfurtner, Florian A.; Garcia-Roman, Jonathan; Köhler, Bianca; Zahler, Stefan; Rädler, Joachim O.; Wagner, Ernst und Roidl, Andreas
(2019):
Inducible microRNA-200c decreases motility of breast cancer cells and reduces filamin A.
In: PLOS One
14(11), e0224314
[PDF, 2MB]
Ljepoja, Bojan; Garcia-Roman, Jonathan; Sommer, Ann-Katrin; Frohlich, Thomas; Arnold, Georg J.; Wagner, Ernst und Roidl, Andreas
(2018):
A proteomic analysis of an in vitro knock-out of miR-200c.
In: Scientific Reports, Bd. 8, 6927
[PDF, 3MB]
Lucke, Matthias; Mottas, Ines; Herbst, Tina; Hotz, Christian; Roemer, Lin; Schierling, Martina; Herold, Heike M.; Slotta, Ute; Spinetti, Thibaud; Scheibel, Thomas; Winter, Gerhard; Bourquin, Carole und Engert, Julia
(2018):
Engineered hybrid spider silk particles as delivery system for peptide vaccines.
In: Biomaterials, Bd. 172: S. 105-115
Maass, Gerd; Zatloukal, Kurt; Schmidt, Walter; Berger, M.; Cotten, Matt; Wagner, Ernst; Birnstiel, Max L. und Buschle, M.
(1994):
The generation of tumor vaccines by adenovirus-enhanced transfection of cytokine genes into tumor cells.
In: Skouteris, George G. (Hrsg.):
Liver carcinogenesis. Berlin u.a.: Springer. S. 467-479
[PDF, 1MB]
Mahapatra, Sujata; Polimeni, Marco; Gentiluomo, Lorenzo; Roessner, Dierk; Friess, Wolfgang; Peters, Guenther H. J.; Streicher, Werner W.; Lund, Mikael und Harris, Pernille
(2021):
Self-Interactions of Two Monoclonal Antibodies: Small-Angle X-ray Scattering, Light Scattering, and Coarse-Grained Modeling.
In: Molecular Pharmaceutics, Bd. 19, Nr. 2: S. 508-519
Maiaru, Maria; Morgan, Oakley B.; Mao, Tianqi; Breitsamer, Michaela; Bamber, Harry; Poehlmann, Max; Schmidt, Mathias V.; Winter, Gerhard; Hausch, Felix und Geranton, Sandrine M.
(2018):
The stress regulator FKBP51: a novel and promising druggable target for the treatment of persistent pain states across sexes.
In: Pain, Bd. 159, Nr. 7: S. 1224-1234
Mailaender-Sanchez, Daniela; Braunsdorf, Christina; Grumaz, Christian; Müller, Christoph; Lorenz, Stefan; Stevens, Philip; Wagener, Jeanette; Hebecker, Betty; Hube, Bernhard; Bracher, Franz; Sohn, Kai und Schaller, Martin
(2017):
Antifungal defense of probiotic Lactobacillus rhamnosus GG is mediated by blocking adhesion and nutrient depletion.
In: PLOS One
12(10), e0184438
[PDF, 5MB]
Martos, Ariadna; Berger, Michelle; Kranz, Wendelin; Spanopoulou, Anna; Menzen, Tim; Friess, Wolfgang; Wuchner, Klaus und Hawe, Andrea
(2020):
Novel High-Throughput Assay for Polysorbate Quantification in Biopharmaceutical Products by Using the Fluorescent Dye DiI.
In: Journal of Pharmaceutical Sciences, Bd. 109, Nr. 1: S. 646-655
Mastrella, Giorgia; Hou, Mengzhuo; Li, Min; Stöcklein, Veit M.; Zdouc, Nina; Vomar, Marie N. M.; Miletic, Hrvoje; Reinhard, Soeren; Herold-Mende, Christel C.; Kleber, Susanne; Eisenhut, Katharina; Gargiulo, Gaetano; Synowitz, Michael; Vescovi, Angelo L.; Harter, Patrick N.; Penninger, Josef M.; Wagner, Ernst; Mittelbronn, Michel; Bjerkvig, Rolf; Hambardzumyan, Dolores; Schueller, Ulrich; Tonn, Jörg-Christian; Radke, Josefine; Glass, Rainer und Kaelin, Roland E.
(2019):
Targeting APLN/APLNR Improves Antiangiogenic Efficiency and Blunts Proinvasive Side Effects of VEGFA/VEGFR2 Blockade in Glioblastoma.
In: Cancer Research, Bd. 79, Nr. 9: S. 2298-2313
Mateus, Pedro; Jacquet, Antoine; Mendez-Ardoy, Alejandro; Boulloy, Alice; Kauffmann, Brice; Pecastaings, Gilles; Buffeteau, Thierry; Ferrand, Yann; Bassani, Dario M. und Huc, Ivan
(2021):
Sensing a binding event through charge transport variations using an aromatic oligoamide capsule.
In: Chemical Science, Bd. 12, Nr. 10: S. 3743-3750
Mbianda, Johanne; Bakail, May; Andre, Christophe; Moal, Gwenaelle; Perrin, Marie E.; Pinna, Guillaume; Guerois, Raphael; Becher, Francois; Legrand, Pierre; Traore, Seydou; Douat, Celine; Guichard, Gilles und Ochsenbein, Francoise
(2021):
Optimal anchoring of a foldamer inhibitor of ASF1 histone chaperone through backbone plasticity.
In: Science Advances, Bd. 7, Nr. 12, eabd9153
Meena, Chhuttan L.; Singh, Dharmendra; Weinmueller, Michael; Reichart, Florian; Dangi, Abha; Marelli, Udaya Kiran; Zahler, Stefan und Sanjayan, Gangadhar J.
(2020):
Novel cilengitide-based cyclic RGD peptides as alpha nu beta(3) integrin inhibitors.
In: Bioorganic & Medicinal Chemistry Letters, Bd. 30, Nr. 8, 127039
Meier, Dennis; Schoof, Benedikt; Wang, Jinhua; Li, Xuesong; Walz, Andreas; Huettig, Annette; Schlichting, Hartmut; Rosu, Frederic; Gabelica, Valerie; Maurizot, Victor; Reichert, Joachim; Papageorgiou, Anthoula C.; Huc, Ivan und Barth, Johannes
(2022):
Structural adaptations of electrosprayed aromatic oligoamide foldamers on Ag(111).
In: Chemical Communications, Bd. 58, Nr. 64: S. 8938-8941
Meier, Christopher; Steinhauer, Tamara N.; Koczian, Fabian; Plitzko, Birte; Jarolim, Katharina; Girreser, Ulrich; Braig, Simone; Marko, Doris; Vollmar, Angelika M. und Clement, Bernd
(2017):
A Dual Topoisomerase Inhibitor of Intense Pro-Apoptotic and Antileukemic Nature for Cancer Treatment.
In: ChemMedChem, Bd. 12, Nr. 5: S. 347-352
Meier, Christopher; Steinhauer, Tamara N.; Koczian, Fabian; Plitzko, Birte; Jarolim, Katharina; Girreser, Ulrich; Braig, Simone; Marko, Doris; Vollmar, Angelika M. und Clement, Bernd
(2017):
Cover Picture: A Dual Topoisomerase Inhibitor of Intense Pro-Apoptotic and Antileukemic Nature for Cancer Treatment (ChemMedChem 5/2017).
In: ChemMedChem, Bd. 12, Nr. 5: S. 346
Meinhold, Sarah; Bauer, Daniela; Huber, Jonas; Merkel, Ulrich; Weissl, Andreas; Zoldak, Gabriel und Rief, Matthias
(2019):
An Active, Ligand-Responsive Pulling Geometry Reports on Internal Signaling between Subdomains of the DnaK Nucleotide-Binding Domain in Single-Molecule Mechanical Experiments.
In: Biochemistry, Bd. 58, Nr. 47: S. 4744-4750
Merk, Henriette; Zhang, Siwei; Lehr, Thorsten; Müller, Christoph; Ulrich, Melanie; Bibb, James A.; Adams, Ralf H.; Bracher, Franz; Zahler, Stefan; Vollmar, Angelika M. und Liebl, Johanna
(2016):
Inhibition of endothelial Cdk5 reduces tumor growth by promoting non-productive angiogenesis.
In: Oncotarget, Bd. 7, Nr. 5: S. 6088-6104
Messner, Martina; Mandl, Melanie M.; Hackl, Mathias W.; Reinhardt, Till; Ardelt, Maximilian A.; Szczepanowska, Karolina; Fraedrich, Julian E.; Waschke, Jens; Jeremias, Irmela; Fux, Anja; Stahl, Matthias; Vollmar, Angelika M.; Sieber, Stephan A. und Pachmayr, Johanna
(2021):
Small molecule inhibitors of the mitochondrial ClpXP protease possess cytostatic potential and re-sensitize chemo-resistant cancers.
In: Scientific Reports, Bd. 11, Nr. 1, 11185
Messner, Martina; Schmitt, Sabine; Ardelt, Maximilian A.; Fröhlich, Thomas; Müller, Martin; Pein, Helmut; Huber-Cantonati, Petra; Ortler, Carina; König, Lars M.; Zobel, Lena; Koeberle, Andreas; Arnold, Georg J.; Rothenfusser, Simon; Kiemer, Alexandra K.; Gerbes, Alexander L.; Zischka, Hans; Vollmar, Angelika M. und Pachmayr, Johanna
(2020):
Metabolic implication of tigecycline as an efficacious second-line treatment for sorafenib-resistant hepatocellular carcinoma.
In: FASEB Journal, Bd. 34, Nr. 9: S. 11860-11882
Michalakis, Stylianos; Fischer, M. Dominik; Schön, Christian; Wilhelm, Barbara; Zobor, Ditta; Muhlfriedel, Regine; Sothilingam, Vithiyanjali; Kohl, Susanne; Peters, Tobias; Zrenner, Eberhart; Bartz-Schmidt, Karl Ulrich; Üffing, Marius; Wissinger, Bernd; Seeliger, Mathias und Biel, Martin
(2017):
Gene Supplementation Therapy for CNGA3-Linked Achromatopsia.
In: Molecular therapy, Bd. 25, Nr. 5: S. 354
Michalakis, Stylianos; Schön, Christian; Becirovic, Elvir und Biel, Martin
(2017):
Gene therapy for achromatopsia.
In: Journal of Gene Medicine, Bd. 19, Nr. 3, e2944
Michalakis, Stylianos; Shaltiel, Lior; Sothilingam, Vithiyanjali; Koch, Susanne; Schludi, Verena; Krause, Stefanie; Zeitz, Christina; Audo, Isabelle; Lancelot, Marie-Elise; Hamel, Christian; Meunier, Isabelle; Preising, Markus N.; Friedburg, Christoph; Lorenz, Birgit; Zabouri, Nawal; Haverkamp, Silke; Garcia Garrido, Marina; Tanimoto, Naoyuki; Seeliger, Mathias W.; Biel, Martin und Wahl-Schott, Christian A.
(2017):
Mosaic synaptopathy and functional defects in Cav1.4 heterozygous mice and human carriers of CSNB2 (vol 23, pg 1538, 2014).
In: Human Molecular Genetics, Bd. 26, Nr. 2: S. 466
Mohammadi, Mariam; Li, Ying; Abebe, Daniel G.; Xie, Yuran; Kandil, Rima; Kraus, Teresa; Gomez-Lopez, Nardhy; Fujiwara, Tomoko und Merkel, Olivia M.
(2016):
Folate receptor targeted three-layered micelles and hydrogels for gene delivery to activated macrophages.
In: Journal of Controlled Release, Bd. 244: S. 269-279
Moser, Christina; Rüdiger, Daniel; Foerster, Florian; Blume, Julia von; Yu, Peng; Kuster, Bernhard; Kazmaier, Uli; Vollmar, Angelika M. und Zahler, Stefan
(2017):
Persistent inhibition of pore-based cell migration by sub-toxic doses of miuraenamide, an actin filament stabilizer.
In: Scientific Reports, Bd. 7, 16407
[PDF, 1MB]
Mosion, Jan; Rauscher, Alexander; Willi, Taylor; Lang, Donna; Vertinsky, Talia; Vila-Rodriguez, Fidel; Kames, Christian; Panenka, William; Jarrett, Mike; Honer, William und Barr, Alasdair
(2016):
A Longitudinal Characterization of Cerebral Microbleeds in a Marginalized Population with High Rates of Mental Illness, Substance Abuse and Viral Infection.
In: Neurology, Bd. 86
Moustakim, Moses; Riedel, Kerstin; Schuller, Marion; Gehring, Andre P.; Monteiro, Octovia P.; Martin, Sarah P.; Fedorov, Oleg; Heer, Jag; Dixon, Darren J.; Elkins, Jonathan M.; Knapp, Stefan; Bracher, Franz und Brennan, Paul E.
(2018):
Discovery of a novel allosteric inhibitor scaffold for polyadenosine-diphosphate-ribose polymerase 14 (PARP14) macrodomain 2.
In: Bioorganic & Medicinal Chemistry, Bd. 26, Nr. 11: S. 2965-2972
Movassaghian, Sara; Xie, Yuran; Hildebrandt, Claudia; Rosati, Rayna; Li, Ying; Kim, Na Hyung; Conti, Denise S.; Rocha, Sandro R. P. da; Yang, Zeng-Quan und Merkel, Olivia M.
(2016):
Post-Transcriptional Regulation of the GASC1 Oncogene with Active Tumor-Targeted siRNA-Nanoparticles.
In: Molecular Pharmaceutics, Bd. 13, Nr. 8: S. 2605-2621
Mueller, Susanne; Ackloo, Suzanne; Al Chawaf, Arij; Al-Lazikani, Bissan; Antolin, Albert; Baell, Jonathan B.; Beck, Hartmut; Beedie, Shaunna; Betz, Ulrich A. K.; Bezerra, Gustavo Arruda; Brennan, Paul E.; Brown, David; Brown, Peter J.; Bullock, Alex N.; Carter, Adrian J.; Chaikuad, Apirat; Chaineau, Mathilde; Ciulli, Alessio; Collins, Ian; Dreher, Jan; Drewry, David; Edfeldt, Kristina; Edwards, Aled M.; Egner, Ursula; Frye, Stephen V.; Fuchs, Stephen M.; Hall, Matthew D.; Hartung, Ingo V.; Hillisch, Alexander; Hitchcock, Stephen H.; Homan, Evert; Kannan, Natarajan; Kiefer, James R.; Knapp, Stefan; Kostic, Milka; Kubicek, Stefan; Leach, Andrew R.; Lindemann, Sven; Marsden, Brian D.; Matsui, Hisanori; Meier, Jordan L.; Merk, Daniel; Michel, Maurice; Morgan, Maxwell R.; Mueller-Fahrnow, Anke; Owen, Dafydd R.; Perry, Benjamin G.; Rosenberg, Saul H.; Saikatendu, Kumar Singh; Schapira, Matthieu; Scholten, Cora; Sharma, Sujata; Simeonov, Anton; Sundstrom, Michael; Superti-Furga, Giulio; Todd, Matthew H.; Tredup, Claudia; Vedadi, Masoud; Delft, Frank von; Willson, Timothy M.; Winter, Georg E.; Workman, Paul und Arrowsmith, Cheryl H.
(2021):
Target 2035-update on the quest for a probe for every protein.
In: Rsc Medicinal Chemistry, Bd. 13, Nr. 1: S. 13-21
Mukhopadhyay, Tufan K. ORCID: https://orcid.org/0000-0001-8888-5373; Willems, Sabine ORCID: https://orcid.org/0000-0002-9755-3394; Arp, Christopher J. ORCID: https://orcid.org/0000-0002-5059-6178; Morstein, Johannes; Haake, Caleb T.; Merk, Daniel ORCID: https://orcid.org/0000-0002-5359-8128 und Trauner, Dirk ORCID: https://orcid.org/0000-0002-6782-6056
(2023):
Development of Light‐Activated LXR Agonists.
In: ChemMedChem, Bd. 18, Nr. 11
[PDF, 5MB]
Murenu, Elisa; Kostidis, Sarantos; Lahiri, Shibojyoti; Geserich, Anna S.; Imhof, Axel; Giera, Martin und Michalakis, Stylianos
(2021):
Metabolic Analysis of Vitreous/Lens and Retina in Wild Type and Retinal Degeneration Mice.
In: International Journal of Molecular Sciences, Bd. 22, Nr. 5, 2345
Murenu, Elisa; Pavlou, Marina; Richter, Lisa; Rapti, Kleopatra; Just, Sabrina; Cehajic-Kapetanovic, Jasmina; Tafrishi, Neda; Hayes, Andrew; Scholey, Rachel; Lucas, Robert; Buening, Hildegard; Grimm, Dirk und Michalakis, Stylianos
(2021):
A universal protocol for isolating retinal ON bipolar cells across species via fluorescence-activated cell sorting.
In: Molecular Therapy-Methods & Clinical Development, Bd. 20: S. 587-600
Mühlfriedel, Regine; Tanimoto, Naoyuki; Schön, Christian; Sothilingam, Vithiyanjali; Garrido, Marina Garcia; Beck, Susanne C.; Huber, Gesine; Biel, Martin; Seeliger, Mathias W. und Michalakis, Stylianos
(2017):
AAV-Mediated Gene Supplementation Therapy in Achromatopsia Type 2: Preclinical Data on Therapeutic Time Window and Long-Term Effects.
In: Frontiers in Neuroscience, Bd. 11, 292
[PDF, 5MB]
Müller, Markus; Liu, Nian; Gujrati, Vipul; Valavalkar, Abha; Hartmann, Sean; Anzenhofer, Pia; Klemm, Uwe; Telek, András; Dietzek‐Ivanšić, Benjamin; Hartschuh, Achim; Ntziachristos, Vasilis und Thorn‐Seshold, Oliver ORCID: https://orcid.org/0000-0003-3981-651X
(2024):
Merged Molecular Switches Excel as Optoacoustic Dyes: Azobenzene–Cyanines Are Loud and Photostable NIR Imaging Agents.
In: Angewandte Chemie International Edition, Bd. 63, Nr. 33
[PDF, 5MB]
Müller, Markus; Niemeyer, Konstantin; Urban, Nicole; Ojha, Navin K.; Zufall, Frank; Leinders-Zufall, Trese; Schäfer, Michael und Thorn-Seshold, Oliver
(2022):
BTDAzo: A Photoswitchable TRPC5 Channel Activator.
In: Angewandte Chemie International Edition, Bd. 61, Nr. 36
[PDF, 11MB]
Müller, Martin; Gerndt, Susanne; Chao, Yu-Kai; Zisis, Themistoklis; Ong, Nam Phuong Nguyen; Gerwien, Aaron; Urban, Nicole; Müller, Christoph; Gegenfurtner, Florian A.; Geisslinger, Franz; Ortler, Carina; Chen, Cheng-Chang; Zahler, Stefan; Biel, Martin; Schäfer, Michael; Grimm, Christian; Bracher, Franz; Vollmar, Angelika M. und Bartel, Karin
(2021):
Gene editing and synthetically accessible inhibitors reveal role for TPC2 in HCC cell proliferation and tumor growth.
In: Cell Chemical Biology, Bd. 28, Nr. 8:
1119-
Müller, Christoph; Neugebauer, Thomas; Zill, Patrizia; Lass-Floerl, Cornelia; Bracher, Franz und Binder, Ulrike
(2018):
Sterol Composition of Clinically Relevant Mucorales and Changes Resulting from Posaconazole Treatment.
In: Molecules, Bd. 23, Nr. 5, 1218
[PDF, 1MB]
Müller-Deku, Adrian; Meiring, Joyce C. M.; Loy, Kristina; Kraus, Yvonne; Heise, Constanze; Bingham, Rebekkah; Jansen, Klara I.; Qu, Xiaoyi; Bartolini, Francesca; Kapitein, Lukas C.; Akhmanova, Anna; Ahlfeld, Julia; Trauner, Dirk und Thorn-Seshold, Oliver
(2020):
Photoswitchable paclitaxel-based microtubule stabilisers allow optical control over the microtubule cytoskeleton.
In: Nature communications, Bd. 11, Nr. 1, 4640
[PDF, 7MB]
Neiens, Patrick; De Simone, Angela; Ramershoven, Anna; Höfner, Georg; Allmendinger, Lars und Wanner, Klaus T.
(2018):
Development and validation of an LC-ESI-MS/MS method for the quantification of D-84, reboxetine and citalopram for their use in MS Binding Assays addressing the monoamine transporters hDAT, hSERT and hNET.
In: Biomedical Chromatography, Bd. 32, Nr. 7, e4231
Nguyen, O. N. Phuong; Böhm, Sybille; Gießl, Andreas; Butz, Elisabeth S.; Wolfrum, Uwe; Brandstätter, Johann H.; Wahl-Schott, Christian; Biel, Martin und Becirovic, Elvir
(2016):
Peripherin-2 differentially interacts with cone opsins in outer segments of cone photoreceptors.
In: Human Molecular Genetics, Bd. 25, Nr. 12: S. 2367-2377
Nguyen, Ong Nam Phuong; Grimm, Christian; Schneider, Lina S.; Chao, Yu-Kai; Atzberger, Carina; Bartel, Karin; Watermann, Anna; Ulrich, Melanie; Mayr, Doris; Wahl-Schott, Christian; Biel, Martin und Vollmar, Angelika M.
(2017):
Two-Pore Channel Function Is Crucial for the Migration of Invasive Cancer Cells.
In: Cancer Research, Bd. 77, Nr. 6: S. 1427-1438
Nino-Pariente, Amaya; Arminan, Ana; Reinhard, Sören; Scholz, Claudia; Kos, Petra; Wagner, Ernst und Vicent, Maria J.
(2017):
Design of Poly-l-Glutamate-Based Complexes for pDNA Delivery (vol 10, 1700029, 2017).
In: Macromolecular Bioscience, Bd. 17, Nr. 10, 1700245
Nitsche, Valentin; Höfner, Georg; Kaiser, Jesko; Gertzen, Christoph G.W.; Seeger, Thomas; Niessen, Karin V.; Steinritz, Dirk; Worek, Franz; Gohlke, Holger; Paintner, Franz F. und Wanner, Klaus T. ORCID: https://orcid.org/0000-0003-4399-1425
(2024):
MS Binding Assays with UNC0642 as reporter ligand for the MB327 binding site of the nicotinic acetylcholine receptor.
In: Toxicology Letters, Bd. 392: S. 94-106
[PDF, 4MB]
Ochakovski, G. Alex; Peters, Tobias; Michalakis, Stylianos; Wilhelm, Barbara; Wissinger, Bernd; Bie, Martin; Bartz-Schmidt, K. Ulrich und Fischer, M. Dominik
(2017):
Subretinal Injection for Gene Therapy Does Not Cause Clinically Significant Outer Nuclear Layer Thinning in Normal Primate Foveae.
In: Investigative Ophthalmology & Visual Science, Bd. 58, Nr. 10: S. 4155-4160
Opolka-Hoffmann, Eugenia; Jordan, Gregor; Otteneder, Michael; Kieferle, Robin; Lechmann, Martin; Winter, Gerhard und Staack, Roland F.
(2021):
The impact of immunogenicity on therapeutic antibody pharmacokinetics: A preclinical evaluation of the effect of immune complex formation and antibody effector function on clearance.
In: Mabs, Bd. 13, Nr. 1, e1995929
Palabiyik-Yucelik, Saziye Sezin; Moser, Simone; Becker, Kathrin; Halici, Zekai; Bayir, Yasin; Stonig, Marlies; Schennach, Harald; Fuchs, Dietmar; Gostner, Johanna M. und Kurz, Katharina
(2021):
Oxyresveratrol modulates the immune response in vitro.
In: Pteridines, Bd. 32, Nr. 1: S. 70-78
Pallauf, Kathrin; Chin, Dawn; Guenther, Ilka; Birringer, Marc; Lueerseni, Kai; Schultheiss, Gerald; Vieten, Sarah; Krauss, Jürgen; Bracher, Franz; Danylec, Nicolas; Soukup, Sebastian T.; Kulling, Sabine E. und Rimbach, Gerald
(2019):
Resveratrol, lunularin and dihydroresveratrol do not act as caloric restriction mimetics when administered intraperitoneally in mice.
In: Scientific Reports, Bd. 9, 4445
[PDF, 1MB]
Panagiotopoulos, Anna-Lena; Karguth, Nina; Pavlou, Marina; Boehm, Sybille; Gasparoni, Gilles; Walter, Joern; Graf, Alexander; Blum, Helmut; Biel, Martin; Riedmayr, Lisa Maria und Becirovic, Elvir
(2020):
Antisense Oligonucleotide- and CRISPR-Cas9-Mediated Rescue of mRNA Splicing for a Deep Intronic CLRN1 Mutation.
In: Molecular Therapy-Nucleic Acids, Bd. 21: S. 1050-1061
Panossian, Alexander G.; Efferth, Thomas; Shikov, Alexander N.; Pozharitskaya, Olga N.; Kuchta, Kenny; Mukherjee, Pulok K.; Banerjee, Subhadip; Heinrich, Michael; Wu, Wanying; Guo, De-an und Wagner, Hildebert
(2020):
Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress- and aging-related diseases.
In: Medicinal Research Reviews, Bd. 41, Nr. 1: S. 630-703
Pappas, Charalampos G.; Mandal, Pradeep K.; Liu, Bin; Kauffmann, Brice; Miao, Xiaoming; Komaromy, David; Hoffmann, Waldemar; Manz, Christian; Chang, Rayoon; Liu, Kai; Pagel, Kevin; Huc, Ivan und Otto, Sijbren
(2020):
Emergence of low-symmetry foldamers from single monomers.
In: Nature Chemistry, Bd. 12, Nr. 12: S. 1180-1186
Pasieka, Anna; Panek, Dawid; Jonczyk, Jakub; Godyn, Justyna; Szalaj, Natalia; Latacz, Gniewomir; Tabor, Julia; Mezeiova, Eva; Chantegreil, Fabien; Dias, Jose; Knez, Damijan; Lu, Junfeng; Pi, Rongbiao; Korabecny, Jan; Brazzolotto, Xavier; Gobec, Stanislav; Hoefner, Georg; Wanner, Klaus; Wieckowska, Anna und Malawska, Barbara
(2021):
Discovery of multifunctional anti-Alzheimer's agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and gamma-aminobutyric acid transporters.
In: European Journal of Medicinal Chemistry, Bd. 218, 113397
Patel, Sajal Manubhai; Nail, Steven L.; Pikal, Michael J.; Geidobler, Raimund; Winter, Gerhard; Hawe, Andrea; Davagnino, Juan und Gupta, Shailaja Rambhatla
(2017):
Lyophilized Drug Product Cake Appearance: What Is Acceptable?
In: Journal of Pharmaceutical Sciences, Bd. 106, Nr. 7: S. 1706-1721
Paulus, Constanze; Rebets, Yuriy; Tokovenko, Bogdan; Nadmid, Suvd; Terekhova, Larisa P.; Myronovskyi, Maksym; Zotchev, Sergey B.; Rückert, Christian; Braig, Simone; Zahler, Stefan; Kalinowski, Jörn und Luzhetskyy, Andriy
(2017):
New natural products identified by combined genomics-metabolomics profiling of marine Streptomyces sp MP131-18.
In: Scientific Reports, Bd. 7, 42382
[PDF, 2MB]
Pergola, Carlo; Schubert, Katrin; Pace, Simona; Ziereisen, Jana; Nikels, Felix; Scherer, Olga; Hüttel, Stephan; Zahler, Stefan; Vollmar, Angelika M.; Weinigel, Christina; Rummler, Silke; Müller, Rolf; Raasch, Martin; Mosig, Alexander; Koeberle, Andreas und Werz, Oliver
(2017):
Modulation of actin dynamics as potential macrophage subtype-targeting anti-tumour strategy.
In: Scientific Reports, Bd. 7, 41434
[PDF, 3MB]
Pfitzer, Lisa; Moser, Christina; Gegenfurtner, Florian; Arner, Anja; Foerster, Florian; Atzberger, Carina; Zisis, Themistoklis; Kubisch-Dohmen, Rebekka; Busse, Johanna; Smith, Rebecca; Timinszky, Gyula; Kalinina, Olga V.; Müller, Rolf; Wagner, Ernst; Vollmar, Angelika M. und Zahler, Stefan
(2019):
Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy.
In: Cell Death & Disease, Bd. 10, UNSP 302
Plesch, Eva; Chen, Cheng-Chang; Butz, Elisabeth; Rosato, Anna Scotto; Krogsaeter, Einar K.; Yinan, Hua; Bartel, Karin; Keller, Marco; Robaa, Dina; Teupser, Daniel; Holdt, Lesca M.; Vollmar, Angelika M.; Sippl, Wolfgang; Puertollano, Rosa; Medina, Diego; Biel, Martin; Wahl-Schott, Christian; Bracher, Franz und Grimm, Christian
(2018):
Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells.
In: eLife, Bd. 7, e39720
[PDF, 4MB]
Podkowa, A.; Sałat, K.; Malikowska, N.; Kern, F.; Pabel, J.; Kulig, K.; Wanner, K. T.; Wojcieszak, E. und Furgala, A.
(2016):
Anticonvulsant activity of a novel gamma-aminobutyric acid transporter subtype 1 inhibitor in mice.
In: European Neuropsychopharmacology, Bd. 26:
S286-S286
Pohl, Christin; Zalar, Matja; El Bialy, Inas; Indrakumar, Sowmya; Peters, Gunther H. J.; Friess, Wolfgang; Golovanov, Alexander P.; Streicher, Werner W.; Noergaard, Allan und Harris, Pernille
(2020):
The Effect of Point Mutations on the Biophysical Properties of an Antimicrobial Peptide: Development of a Screening Protocol for Peptide Stability Screening.
In: Molecular Pharmaceutics, Bd. 17, Nr. 9: S. 3298-3313
Popp, Tobias A.; Tallant, Cynthia; Rogers, Catherine; Fedorov, Oleg; Brennan, Paul E.; Müller, Susanne; Knapp, Stefan und Bracher, Franz
(2016):
Development of Selective CBP/P300 Benzoxazepine Bromodomain Inhibitors.
In: Journal of Medicinal Chemistry, Bd. 59, Nr. 19: S. 8889-8912
Pozo, Karine; Ishimatsu, Keisuke; Telange, Rahul; Takahashi, Masaya; Oltmann, Sarah; Zahler, Stefan und Bibb, James
(2017):
Novel Combinatorial Drug Therapy for MTC.
In: Pancreas, Bd. 46, Nr. 3: S. 428-429
Pöhlmann, M. L.; Hartmann, J.; Harbich, D.; Schmid, B.; Häusl, A. S.; Dedic, N.; Feng, X.; Hausch, F.; Breitsamer, M.; Winter, G.; Deussing, J. und Schmidt, M. V.
(2017):
Unraveling the functional contribution of FKBP-51 in monoaminergic brain areas to stress vulnerability in mice.
In: European Neuropsychopharmacology, Bd. 27:
S39-S39
Pöhlmann, Max L.; Häusl, Alexander S.; Harbich, Daniela; Balsevich, Georgia; Engelhardt, Clara; Feng, Xixi; Breitsamer, Michaela; Hausch, Felix; Winter, Gerhard und Schmidt, Mathias V.
(2018):
Pharmacological Modulation of the Psychiatric Risk Factor FKBP51 Alters Efficiency of Common Antidepressant Drugs.
In: Frontiers in Behavioral Neuroscience, Bd. 12, 262
[PDF, 1MB]
Rappenglück, Sebastian; Sichler, Sonja; Höfner, Georg; Wein, Thomas; Niessen, Karin V.; Seeger, Thomas; Paintner, Franz F.; Worek, Franz; Thiermann, Horst und Wanner, Klaus T.
(2018):
Synthesis of a Series of Non-Symmetric Bispyridinium and Related Compounds and Their Affinity Characterization at the Nicotinic Acetylcholine Receptor.
In: Chemmedchem, Bd. 13, Nr. 24: S. 2653-2663
Rappenglück, Sebastian; Sichler, Sonja; Höfner, Georg; Wein, Thomas; Niessen, Karin V.; Seeger, Thomas; Paintner, Franz F.; Worek, Franz; Thiermann, Horst und Wanner, Klaus T.
(2018):
Synthesis of a Series of Structurally Diverse MB327 Derivatives and Their Affinity Characterization at the Nicotinic Acetylcholine Receptor.
In: Chemmedchem, Bd. 13, Nr. 17: S. 1806-1816
Rarova, Lucie; Sedlak, David; Oklestkova, Jana; Steigerova, Jana; Liebl, Johanna; Zahler, Stefan; Bartunek, Petr; Kolar, Zdenek; Kohout, Ladislav; Kvasnica, Miroslav und Strnad, Miroslav
(2018):
The novel brassinosteroid analog BR4848 inhibits angiogenesis in human endothelial cells and induces apoptosis in human cancer cells in vitro.
In: Journal of Steroid Biochemistry and Molecular Biology, Bd. 178: S. 263-271
Reichel, Christoph A.; Hessenauer, Maximilian E. T.; Pflieger, Kerstin; Rehberg, Markus; Kanse, Sandip M.; Zahler, Stefan; Krombach, Fritz; Berghaus, Alexander und Strieth, Sebastian
(2015):
Components of the Plasminogen Activation System Promote Engraftment of Porous Polyethylene Biomaterial via Common and Distinct Effects.
In: PLOS ONE
10(2), e0116883
[PDF, 4MB]
Reichel, Felix F.; Dauletbekov, Daniyar L.; Klein, Reinhild; Peters, Tobias; Ochakoyski, G. Alex; Seitz, Immanuel P.; Wilhelm, Barbara; Üffing, Marius; Biel, Martin; Wissinger, Bernd; Michalakis, Stylianos; Bartz-Schmidt, Karl Ulrich und Fischer, M. Dominik
(2017):
AAV8 Can Induce Innate and Adaptive Immune Response in the Primate Eye.
In: Molecular therapy, Bd. 25, Nr. 12: S. 2648-2660
Reichel, Felix Friedrich; Peters, Tobias; Muehlfriedel, Regine; Biel, Martin; Paquet-Durand, Francois; Ueffing, Marius; Wissinger, Bernd; Bartz-Schmidt, Karl Ulrich; Fischer, M. Dominik und Michalakis, Stylianos
(2016):
Humoral immune response to subretinal AAV8 in non-human primates.
In: Investigative Ophthalmology & Visual Science, Bd. 57, Nr. 12
Reynders, Martin; Garścia, Małgorzata; Müller-Deku, Adrian; Wranik, Maximilian; Krauskopf, Kristina; Osa de la Rosa, Luis de la; Schaffer, Konstantin; Jötten, Anna; Rode, Alexander; Stierle, Valentin; Kraus, Yvonne; Baumgartner, Benedikt; Ali, Ahmed; Bubeneck, Andrei; Seal, Trina; Steinmetz, Michel O.; Paulitschke, Philipp und Thorn-Seshold, Oliver ORCID: https://orcid.org/0000-0003-3981-651X
(2024):
A photo-SAR study of photoswitchable azobenzene tubulin-inhibiting antimitotics identifying a general method for near-quantitative photocontrol.
In: Chemical Science, Bd. 15, Nr. 31: S. 12301-12309
[PDF, 4MB]
Riedmayr, Lisa M.
(2020):
SMaRT for Therapeutic Purposes.
In: Li, Hui und Elfman, Justin (Hrsg.):
Chimeric RNA. Methods in molecular biology : Methods and Protocols, Bd. 2079. New York, NY: Springer Nature. S. 219-232
Rieser, Ruth; Koch, Johanna; Faccioli, Greta; Richter, Klaus; Menzen, Tim; Biel, Martin; Winter, Gerhard und Michalakis, Stylianos
(2021):
Comparison of Different Liquid Chromatography-Based Purification Strategies for Adeno-Associated Virus Vectors.
In: Pharmaceutics, Bd. 13, Nr. 5, 748
Rodrigues, Leticia; Raftopoulos, Konstantinos N.; Schmidt, Signe Tandrup; Schneider, Fabian; Dietz, Hendrik; Rades, Thomas; Franzyk, Henrik; Pedersen, Anders Elm; Papadakis, Christine M.; Christensen, Dennis; Winter, Gerhard; Foged, Camilla und Hubert, Madlen
(2018):
Immune responses induced by nano-self-assembled lipid adjuvants based on a monomycoloyl glycerol analogue after vaccination with the Chlamydia trachomatis major outer membrane protein.
In: Journal of Controlled Release, Bd. 285: S. 12-22
Rodrigues, Leticia; Schneider, Fabian; Zhang, Xiaohan; Larsson, Elin; Moodie, Lindon W. K.; Dietz, Hendrik; Papadakis, Christine M.; Winter, Gerhard; Lundmark, Richard und Hubert, Madlen
(2019):
Cellular uptake of self-assembled phytantriol-based hexosomes is independent of major endocytic machineries.
In: Journal of Colloid and Interface Science, Bd. 553: S. 820-833
Rubio, Karla; Singh, Indrabahadur; Dobersch, Stephanie; Sarvari, Pouya; Guenther, Stefan; Cordero, Julio; Mehta, Aditi; Wujak, Lukasz; Cabrera-Fuentes, Hector; Chao, Cho-Ming; Braubach, Peter; Bellusci, Saverio; Seeger, Werner; Guenther, Andreas; Preissner, Klaus T.; Wygrecka, Malgorzata; Savai, Rajkumar; Papy-Garcia, Dulce; Dobreva, Gergana; Heikenwalder, Mathias; Savai-Pullamsetti, Soni; Braun, Thomas und Barreto, Guillermo
(2019):
Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis.
In: Nature Communications, Bd. 10, 2229
[PDF, 3MB]
Rushworth, James L.; Thawani, Aditya R.; Fajardo-Ruiz, Elena; Meiring, Joyce C. M.; Heise, Constanze; White, Andrew J. P.; Akhmanova, Anna; Brandt, Jochen R.; Thorn-Seshold, Oliver und Fuchter, Matthew J.
(2022):
[5]-Helistatins: Tubulin-Binding Helicenes with Antimitotic Activity.
In: JACS Au, Bd. 2, Nr. 11: S. 2561-2570
Röder, Ruth; Preiß, Tobias; Hirschle, Patrick; Steinborn, Benjamin; Zimpel, Andreas; Höhn, Miriam; Rädler, Joachim O.; Bein, Thomas; Wagner, Ernst; Wuttke, Stefan und Lächelt, Ulrich
(2017):
Multifunctional Nanoparticles by Coordinative Self-Assembly of His Tagged Units with Metal Organic Frameworks.
In: Journal of the American Chemical Society, Bd. 139, Nr. 6: S. 2359-2368
Sailer, Alexander; Ermer, Franziska; Kraus, Yvonne; Lutter, Ferdinand H.; Donau, Carsten; Bremerich, Maximilian; Ahlfeld, Julia und Thorn-Seshold, Oliver
(2019):
Hemithioindigos for Cellular Photopharmacology: Desymmetrised Molecular Switch Scaffolds Enabling Design Control over the Isomer-Dependency of Potent Antimitotic Bioactivity.
In: Chembiochem, Bd. 20, Nr. 10: S. 1305-1314
Santos-Ferreira, Tiago; Herbig, Maik; Otto, Oliver; Carido, Madalena; Karl, Mike O.; Michalakis, Stylianos; Guck, Jochen und Ader, Marius
(2019):
Morpho-Rheological Fingerprinting of Rod Photoreceptors Using Real-Time Deformability Cytometry.
In: Cytometry Part A, Bd. 95, Nr. 11: S. 1145-1157
Santos-Ferreira, Tiago; Völkner, Manuela; Borsch, Oliver; Haas, Jochen; Cimalla, Peter; Vasudevan, Praveen; Carmeliet, Peter; Corbeil, Denis; Michalakis, Stylianos; Koch, Edmund; Karl, Mike O. und Ader, Marius
(2016):
Author Response: Possibility of Cytoplasmic Transportation Between Donor-Host Cell Following Photoreceptor Transplantation.
In: Investigative Ophthalmology & Visual Science, Bd. 57, Nr. 13: S. 5336-5337
Sałat, Kinga; Podkowa, Adrian; Malikowska, Natalia; Kern, Felix; Pabel, Jörg; Wojcieszak, Ewelina; Kulig, Katarzyna; Wanner, Klaus T.; Strach, Beata und Wyska, Elżbieta
(2017):
Novel, highly potent and in vivo active inhibitor of GABA transporter subtype 1 with anticonvulsant, anxiolytic, antidepressant and antinociceptive properties.
In: Neuropharmacology, Bd. 113: S. 331-342
Schanzer, Sonja; Koch, Martin; Kiefer, Andreas; Jentke, Thalia; Veith, Michael; Bracher, Franz; Bracher, Johannes und Mueller, Christoph
(2022):
Analysis of pesticide and persistent organic pollutant residues in German bats.
In: Chemosphere, Bd. 305, 135342
Schepmann, Dirk; Neue, Christina; Westphaelinger, Stefanie; Müller, Christoph; Bracher, Franz; Lange, Carsten; Bednarski, Patrick; Almansa, Carmen; Friedland, Kristina; Raebiger, Vivien; Duefer, Martina und Wuensch, Bernhard
(2019):
Pharmacological characterization of high-affinity sigma(1) receptor ligands with spirocyclic thienopyran and thienofuran scaffold.
In: Journal of Pharmacy and Pharmacology, Bd. 72, Nr. 2: S. 236-248
Schmacke, Niklas A.; O'Duill, Fionan; Gaidt, Moritz M.; Szymanska, Inga; Kamper, Julia M.; Schmid-Burgk, Jonathan L.; Maedler, Sophia C.; Mackens-Kiani, Timur; Kozaki, Tatsuya; Chauhan, Dhruv; Nagl, Dennis; Stafford, Che A.; Harz, Hartmann; Froehlich, Adrian L.; Pinci, Francesca; Ginhoux, Florent; Beckmann, Roland; Mann, Matthias; Leonhardt, Heinrich und Hornung, Veit
(2022):
IKKO primes inflammasome formation by recruiting NLRP3 to the trans-Golgi network.
In: Immunity, Bd. 55, Nr. 12: S. 2271-2284
Schmitt, Carina ORCID: https://orcid.org/0009-0006-5118-3785; Mauker, Philipp ORCID: https://orcid.org/0009-0007-8740-7864; Vepřek, Nynke A. ORCID: https://orcid.org/0000-0001-7301-265X; Gierse, Carolin ORCID: https://orcid.org/0009-0002-7918-7877; Meiring, Joyce C. M. ORCID: https://orcid.org/0000-0001-9166-5363; Kuch, Jürgen; Akhmanova, Anna; Dehmelt, Leif ORCID: https://orcid.org/0000-0002-6559-6496 und Thorn‐Seshold, Oliver ORCID: https://orcid.org/0000-0003-3981-651X
(2024):
A Photocaged Microtubule‐Stabilising Epothilone Allows Spatiotemporal Control of Cytoskeletal Dynamics.
In: Angewandte Chemie International Edition
[PDF, 5MB]
Schmitt, Andreas; Rödel, Philipp; Anamur, Cihad; Seeliger, Claudine; Imhoff, Andreas B.; Herbst, Elmar; Vogt, Stephan; Griensven, Martijn van; Winter, Gerhard und Engert, Julia
(2015):
Calcium Alginate Gels as Stem Cell Matrix - Making Paracrine Stem Cell Activity Available for Enhanced Healing after Surgery.
In: PLOS ONE
10(3), e0118937
[PDF, 1MB]
Schmohl, Kathrin A.; Dolp, Patrick; Schug, Christina; Knoop, Kerstin; Klutz, Kathrin; Schwenk, Nathalie; Bartenstein, Peter; Nelson, Peter J.; Ogris, Manfred; Wagner, Ernst und Spitzweg, Christine
(2017):
Reintroducing the Sodium-Iodide Symporter to Anaplastic Thyroid Carcinoma.
In: Thyroid, Bd. 27, Nr. 12: S. 1534-1543
Schnitzler, Lukas G.; Junger, Stefanie; Loy, Dominik M.; Wagner, Ernst; Wixforth, Achim; Hoerner, Andreas; Laechelt, Ulrich und Westerhausen, Christoph
(2019):
Size tunable nanoparticle formation employing droplet fusion by acoustic streaming applied to polyplexes.
In: Journal of Physics D-Applied Physics, Bd. 52, Nr. 24, 244002
Schug, Christina; Kitzberger, Carolin; Sievert, Wolfgang; Spellerberg, Rebekka; Tutter, Mariella; Schmohl, Kathrin A.; Eberlein, Bernadette; Biedermann, Tilo; Steiger, Katja; Zach, Christian; Schwaiger, Markus; Multhoff, Gabriele; Wagner, Ernst; Nelson, Peter J. und Spitzweg, Christine
(2019):
Radiation-Induced Amplification of TGFB1-Induced Mesenchymal Stem Cell-Mediated Sodium Iodide Symporter (NIS) Gene I-131 Therapy.
In: Clinical Cancer Research, Bd. 25, Nr. 19: S. 5997-6008
Schug, Christina; Sievert, Wolfgang; Urnauer, Sarah; Müller, Andrea M.; Schmohl, Kathrin A.; Wechselberger, Alexandra; Schwenk, Nathalie; Lauber, Kirsten; Schwaiger, Markus; Multhoff, Gabriele; Wagner, Ernst; Nelson, Peter J. und Spitzweg, Christine
(2018):
External Beam Radiation Therapy Enhances Mesenchymal Stem Cell-Mediated Sodium-Iodide Symporter Gene Delivery.
In: Human Gene Therapy, Bd. 29, Nr. 11: S. 1287-1300
Schug, Christina; Urnauer, Sarah; Jaeckel, Carsten; Schmohl, Kathrin A.; Tutter, Mariella; Steiger, Katja; Schwenk, Nathalie; Schwaiger, Markus; Wagner, Ernst; Nelson, Peter J. und Spitzweg, Christine
(2019):
TGFB1-driven mesenchymal stem cell-mediated NIS gene transfer.
In: Endocrine-Related Cancer, Bd. 26, Nr. 1: S. 89-101
Schuller, Marion; Riede, Kerstin; Gibbs-Seymour, Ian; Uth, Kristin; Sieg, Christian; Gehring, Andre P.; Ahel, Ivan; Bracher, Franz; Kessler, Benedikt M.; Elkins, Jonathan M. und Knapp, Stefan
(2017):
Discovery of a Selective Allosteric Inhibitor Targeting Macrodomain 2 of Polyadenosine-Diphosphate-Ribose Polymerase 14.
In: ACS Chemical Biology, Bd. 12, Nr. 11: S. 2866-2874
Schuster, Simon L.; Segerer, Felix J.; Gegenfurtner, Florian A.; Kick, Kerstin; Schreiber, Christoph; Albert, Max; Vollmar, Angelika M.; Rädler, Joachim O. und Zahler, Stefan
(2016):
Contractility as a global regulator of cellular morphology, velocity, and directionality in low-adhesive fibrillary micro-environments.
In: Biomaterials, Bd. 102: S. 137-147
Schön, Christian; Asteriti, Sabrina; Koch, Susanne; Sothilingam, Vithiyanjali; Garrido, Marina Garcia; Tanimoto, Naoyuki; Herms, Jochen; Seeliger, Mathias W.; Cangiano, Lorenzo; Biel, Martin und Michalakis, Stylianos
(2016):
Loss of HCN1 enhances disease progression in mouse models of CNG channel-linked retinitis pigmentosa and achromatopsia.
In: Human Molecular Genetics, Bd. 25, Nr. 6: S. 1165-1175
Schön, Christian; Sothilingam, Vithiyanjali; Mühlfriedel, Regine; Garrido, Marina Garcia; Beck, Susanne C.; Tanimoto, Naoyuki; Wissinger, Bernd; Paquet-Durand, Francois; Biel, Martin; Michalakis, Stylianos und Seeliger, Mathias W.
(2017):
Gene Therapy Successfully Delays Degeneration in a Mouse Model of PDE6A-Linked Retinitis Pigmentosa (RP43).
In: Human Gene therapy, Bd. 28, Nr. 12: S. 1180-1188
Seitz, Immanuel Philipp; Fischer, M. Dominik; Michalakis, Stylianos; Wilhelm, Barbara; Kahle, Nadine; Zrenner, Eberhart; Ueffing, Marius; Bartz-Schmidt, Karl Ulrich; Biel, Martin; Wissinger, Bernd und Peters, Tobias
(2016):
rAAV8 biodistribution and shedding after subretinal injection in non-human primates.
In: Investigative Ophthalmology & Visual Science, Bd. 57, Nr. 12
Shen, Jie; Roy, Arundhati; Joshi, Himanshu; Samineni, Laxmicharan; Ye, Ruijuan; Tu, Yu-Ming; Song, Woochul; Skiles, Matthew; Kumar, Manish; Aksimentiev, Aleksei und Zeng, Huaqiang
(2022):
Fluorofoldamer-Based Salt- and Proton-Rejecting Artificial Water Channels for Ultrafast Water Transport.
In: Nano Letters, Bd. 22, Nr. 12: S. 4831-4838
Sibbing, Dirk; Aradi, Daniel; Jacobshagen, Claudius; Gross, Lisa; Trenk, Dietmar; Geisler, Tobias; Orban, Martin; Gori, Tommaso; Hadamitzky, Martin; Merkely, Bela; Kiss, Robert Gabor; Komocsi, Andras; Dersi, Csaba A.; Thalmeier, Andreas; Loew, Anja; Holdt, Lesca; Teupser, Daniel; Ince, Hueseyin; Felix, Stephan B.; Parma, Radoslaw; Malek, Lukasz; Horstkotte, Jan; Bay-lacher, Monika; Schwinger, Robert; Rieber, Johannes; Mudra, Harald; Hausleiter, Jörg; Huber, Kurt; Neumann, Franz-Josef; Koltowski, Lukasz; Huczek, Zenon; Mehilli, Julinda und Massberg, Steffen
(2017):
A randomised trial on platelet function-guided de-escalation of antiplatelet treatment in ACS patients undergoing PCI Rationale and design of the Testing Responsiveness to Platelet Inhibition on Chronic Antiplatelet Treatment for Acute Coronary Syndromes (TROPICAL-ACS) Trial.
In: Thrombosis and Haemostasis, Bd. 117, Nr. 1: S. 188-195
Sichler, Sonja; Höfner, Georg ORCID: https://orcid.org/0000-0002-7957-4503; Nitsche, Valentin; Niessen, Karin V.; Seeger, Thomas; Worek, Franz; Paintner, Franz F. und Wanner, Klaus T. ORCID: https://orcid.org/0000-0003-4399-1425
(2024):
Screening for new ligands of the MB327-PAM-1 binding site of the nicotinic acetylcholine receptor.
In: Toxicology Letters, Bd. 394: S. 23-31
[PDF, 2MB]
Sichler, S.; Höfner, G.; Rappenglück, S.; Wein, T.; Niessen, V.; Seeger, T.; Worek, F.; Thiermann, H.; Paintner, F. und Wanner, K. T.
(2018):
Development of MS Binding Assays targeting the binding site of MB327 at the nicotinic acetylcholine receptor.
In: Toxicology Letters, Bd. 293: S. 172-183
Siepmann, Jürgen; Faham, Amina; Clas, Sophie-Dorothee; Boyd, Ben J.; Jannin, Vincent; Bernkop-Schnuerch, Andreas; Zhao, Hang; Lecommandoux, Sebastien; Evans, James C.; Allen, Christine; Merkel, Olivia M.; Costabile, Gabriella; Alexander, Morgan R.; Wildman, Ricky D.; Roberts, Clive J. und Leroux, Jean-Christophe
(2019):
Lipids and polymers in pharmaceutical technology: Lifelong companions.
In: International Journal of Pharmaceutics, Bd. 558: S. 128-142
Singh, Amrita; Saha, Tanumoy; Begemann, Isabell; Ricker, Andrea; Nuesse, Harald; Thorn-Seshold, Oliver; Klingauf, Jürgen; Galic, Milos und Matis, Maja
(2018):
Polarized microtubule dynamics directs cell mechanics and coordinates forces during epithelial morphogenesis.
In: Nature Cell Biology, Bd. 20, Nr. 10: S. 1126-1133
Siow, Wei Xiong; Kabiri, Yaschar; Tang, Rachel; Chao, Yu-Kai; Plesch, Eva; Eberhagen, Carola; Flenkenthaler, Florian; Froehlich, Thomas; Bracher, Franz; Grimm, Christian; Biel, Martin; Zischka, Hans; Vollmar, Angelika M. und Bartel, Karin
(2022):
Lysosomal TRPML1 regulates mitochondrial function in hepatocellular carcinoma cells.
In: Journal of Cell Science, Bd. 135, Nr. 6, jcs259455
Sobiech, Thomas A.; Zhong, Yulong; Sanchez, Laura S. B.; Kauffmann, Brice; McGrath, Jillian K.; Scalzo, Christina; Miller, Daniel P.; Huc, Ivan; Zurek, Eva; Ferrand, Yann und Gong, Bing
(2021):
Stable pseudo[3]rotaxanes with strong positive binding cooperativity based on shape-persistent aromatic oligoamide macrocycles.
In: Chemical Communications, Bd. 57, Nr. 88: S. 11645-11648
Sohail, Azmat; Jayaraman, Kumaresan; Venkatesan, Santhoshkannan; Gotfryd, Kamil; Daerr, Markus; Gether, Ulrik; Loland, Claus J.; Wanner, Klaus T.; Freissmuth, Michael; Sitte, Harald H.; Sandtner, Walter und Stockner, Thomas
(2016):
The Environment Shapes the Inner Vestibule of LeuT.
In: PLOS Computational Biology
12(11), e1005197
[PDF, 5MB]
Soltysinska, Ewa; Bentzen, Bo Hjorth; Barthmes, Maria; Hattel, Helle; Thrush, A. Brianne; Harper, Mary-Ellen; Qvortrup, Klaus; Larsen, Filip J.; Schiffer, Tomas A.; Losa-Reyna, Jose; Straubinger, Julia; Kniess, Angelina; Thomsen, Morten Bækgaard; Brüggemann, Andrea; Fenske, Stefanie; Biel, Martin; Ruth, Peter; Wahl-Schott, Christian; Boushel, Robert Christopher; Olesen, Søren-Peter und Lukowski, Robert
(2014):
KCNMA1 Encoded Cardiac BK Channels Afford Protection against Ischemia-Reperfusion Injury.
In: PLOS ONE
9(7), e103402
[PDF, 1MB]
Sommer, Ann-Katrin; Falcenberg, Mathias; Ljepoja, Bojan; Fröhlich, Thomas; Arnold, Georg J.; Wagner, Ernst und Roidl, Andreas
(2019):
Downregulation of GRK5 hampers the migration of breast cancer cells.
In: Scientific Reports, Bd. 9, 15548
[PDF, 5MB]
Steinborn, Benjamin; Hirschle, Patrick; Höhn, Miriam; Bauer, Tobias; Barz, Matthias; Wuttke, Stefan; Wagner, Ernst und Lächelt, Ulrich
(2019):
Core‐Shell Functionalized Zirconium‐Pemetrexed Coordination Nanoparticles as Carriers with a High Drug Content.
In: Advanced Therapeutics, Bd. 2, Nr. 11
[PDF, 7MB]
Stieglitz, David; Lamm, Susanne; Braig, Simone; Feuerer, Lena; Kuphal, Silke; Dietrich, Peter; Arndt, Stephanie; Echtenacher, Bernd; Hellerbrand, Claus; Karrer, Sigrid und Bosserhoff, Anja-Katrin
(2019):
BMP6-induced modulation of the tumor micro-milieu.
In: Oncogene, Bd. 38, Nr. 5: S. 609-621
Stieglitz, Marc S.; Fenske, Stefanie; Hammelmann, Verena; Becirovic, Elvir; Schöttle, Verena; Delorme, James E.; Schöll-Weidinger, Martha; Mader, Robert; Deussing, Jan; Wolfer, David P.; Seeliger, Mathias W.; Albrecht, Urs; Wotjak, Carsten T.; Biel, Martin; Michalakis, Stylianos und Wahl-Schott, Christian
(2018):
Disturbed Processing of Contextual Information in HCN3 Channel Deficient Mice.
In: Frontiers in Molecular Neuroscience, Bd. 10, 436
[PDF, 4MB]
Svilenov, Hristo ORCID: https://orcid.org/0000-0001-5863-9569; Kulakova, Alina; Zalar, Matja; Golovanov, Alexander P.; Harris, Pernille und Winter, Gerhard
(Januar 2020):
Orthogonal Techniques to Study the Effect of pH, Sucrose, and Arginine Salts on Monoclonal Antibody Physical Stability and Aggregation During Long-Term Storage.
In: Journal of Pharmaceutical Sciences, Bd. 109, Nr. 1: S. 584-594
[PDF, 2MB]
Tallet, Lorene; Frisch, Emilie; Bornerie, Megane; Medemblik, Claire; Frisch, Benoit; Lavalle, Philippe; Guichard, Gilles; Douat, Celine und Kichler, Antoine
(2022):
Design of Oligourea-Based Foldamers with Antibacterial and Antifungal Activities.
In: Molecules, Bd. 27, Nr. 5, 1749
Thuermer, Maria; Gollowitzer, Andre; Pein, Helmut; Neukirch, Konstantin; Gelmez, Elif; Waltl, Lorenz; Wielsch, Natalie; Winkler, Rene; Loeser, Konstantin; Grander, Julia; Hotze, Madlen; Harder, Sonke; Doeding, Annika; Messner, Martina; Troisi, Fabiana; Ardelt, Maximilian; Schlueter, Hartmut; Pachmayr, Johanna; Gutierrez-Gutierrez, Oscar; Rudolph, Karl Lenhard; Thedieck, Kathrin; Schulze-Spaete, Ulrike; Gonzalez-Estevez, Cristina; Kosan, Christian; Svatos, Ales; Kwiatkowski, Marcel und Koeberle, Andreas
(2022):
PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling.
In: Nature Communications, Bd. 13, Nr. 1, 2982
Tobias, Peters; Philipp, Seitz Immanuel; Stylianos, Michalakis; Martin, Biel; Barbara, Wilhelm; Felix, Reichel; Alexander, Ochakovski Guy; Eberhart, Zrenner; Marius, Ueffing; Birgit, Korbmacher; Sven, Korte; Ulrich, Bartz-Schmidt Karl; Dominik, Fischer Manuel; Bartz-Schmidt, Karl Ulrich; Bolz, Sylvia; Fischer, Dominik; Kohl, Susanne; Kuehlewein, Laura; Muehlfriedel, Regine; Neubauer, Jonas; Ochakovski, Alex; Paquet-Durand, Francois; Seeliger, Mathias; Sothilingam, Vithiyanjali; Ueffing, Marius; Weisschuh, Nicole; Wissinger, Bernd; Zhour, Ahmad; Zobor, Ditta; Zrenner, Eberhart; Biel, Martin; Michalakis, Stylianos; Schön, Christian; Kahle, Nadine; Peters, Tobias; Wilhelm, Barbara; Tsang, Steven und Gloeckner, Christian Johannes
(2019):
Safety and Toxicology of Ocular Gene Therapy with Recombinant AAV Vector rAAV.hCNGA3 in Nonhuman Primates.
In: Human Gene Therapy Clinical Development, Bd. 30, Nr. 2: S. 50-56
Tran, Quy Thi Ngoc; Lee, Regina Ching Hua; Liu, Hon Jin; Ran, Danli; Low, Vincent Zhan Lin; To, Dong Quang; Chu, Justin Jang Hann und Chai, Christina Li Lin
(2022):
Discovery and development of labdane-oxindole hybrids as small-molecule inhibitors against chikungunya virus infection.
In: European Journal of Medicinal Chemistry, Bd. 230, 114110
Truebenbach, Ines; Zhang, Wei; Wang, Yanfang; Kern, Sarah; Hoehn, Miriam; Reinhard, Soeren; Gorges, Jan; Kazmaier, Uli und Wagner, Ernst
(2019):
Co-delivery of pretubulysin and siEG5 to EGFR overexpressing carcinoma cells.
In: International Journal of Pharmaceutics, Bd. 569, 118570
Trübenbach, Ines; Gorges, Jan; Kuhn, Jasmin; Kern, Sarah; Baratti, Emanuele; Kazmaier, Uli; Wagner, Ernst und Lächelt, Ulrich
(2017):
Sequence-Defined Oligoamide Drug Conjugates of Pretubulysin and Methotrexate for Folate Receptor Targeted Cancer Therapy.
In: Macromolecular Bioscience, Bd. 17, Nr. 10, 1600520
Unzue, Andrea; Jessen-Trefzer, Claudia; Spiliotopoulos, Dimitrios; Gaudio, Eugenio; Tarantelli, Chiara; Dong, Jing; Zhao, Hongtao; Pachmayr, Johanna; Zahler, Stefan; Bernasconi, Elena; Sartori, Giulio; Cascione, Luciano; Bertoni, Francesco; Sledz, Pawel; Caflisch, Amedeo und Nevado, Cristina
(2020):
Understanding the mechanism of action of pyrrolo[3,2-b]quinoxaline-derivatives as kinase inhibitors.
In: Rsc Medicinal Chemistry, Bd. 11, Nr. 6: S. 665-675
Unzue, Andrea; Lafleur, Karine; Zhao, Hongtao; Zhou, Ting; Dong, Jing; Kolb, Peter; Liebl, Johanna; Zahler, Stefan; Caflisch, Amedeo und Nevado, Cristina
(2016):
Three stories on Eph kinase inhibitors: From in silico discovery to in vivo validation.
In: European Journal of Medicinal Chemistry, Bd. 112: S. 347-366
Urnauer, Sarah; Klutz, Kathrin; Grünwald, Geoffrey K.; Morys, Stephan; Schwenk, Nathalie; Zach, Christian; Gildehaus, Franz-Josef; Rödl, Wolfgang; Ogris, Manfred; Wagner, Ernst und Spitzweg, Christine
(2017):
Systemic tumor-targeted sodium iodide symporter (NIS) gene therapy of hepatocellular carcinoma mediated by B6 peptide polyplexes.
In: Journal of Gene Medicine, Bd. 19, Nr. 5, e2957
Urnauer, Sarah; Müller, Andrea M.; Schug, Christina; Schmohl, Kathrin A.; Tutter, Mariella; Schwenk, Nathalie; Rödl, Wolfgang; Morys, Stephan; Ingrisch, Michäl; Bertram, Jens; Bartenstein, Peter; Clevert, Dirk-André; Wagner, Ernst und Spitzweg, Christine
(2017):
EGFR-targeted nonviral NIS gene transfer for bioimaging and therapy of disseminated colon cancer metastases.
In: Oncotarget, Bd. 8, Nr. 54: S. 92195-92208
Urnauer, Sarah; Schmohl, Kathrin A.; Tutter, Mariella; Schug, Christina; Schwenk, Nathalie; Morys, Stephan; Ziegler, Sibylle; Bartenstein, Peter; Clevert, Dirk-Andre; Wagner, Ernst und Spitzweg, Christine
(2019):
Dual-targeted NIS polyplexes-a theranostic strategy toward tumors with heterogeneous receptor expression.
In: Gene Therapy, Bd. 26, Nr. 3-4: S. 93-108
Urushibara, Ko; Ferrand, Yann; Liu, Zhiwei; Katagiri, Kosuke; Kawahata, Masatoshi; Morvan, Estelle; D'Elia, Ryan; Pophristic, Vojislava; Tanatani, Aya und Huc, Ivan
(2021):
Accessing Improbable Foldamer Shapes with Strained Macrocycles.
In: Chemistry - A European Journal, Bd. 27, Nr. 43: S. 11205-11215
Vallade, MaeIle; Jewginski, Michal; Fischer, Lucile; Buratto, Jeremie; Bathany, Katell; Schmitter, Jean-Marie; Stupfel, Marine; Godde, Frederic; Mackereth, Cameron D. und Huc, Ivan
(2019):
Assessing Interactions between Helical Aromatic Oligoamide Foldamers and Protein Surfaces: A Tethering Approach.
In: Bioconjugate Chemistry, Bd. 30, Nr. 1: S. 54-62
Vlugt, Lucien E. P. M. van der; Eger, Katrien; Müller, Christoph; Ninaber, Dennis K.; Zarcone, Maria C.; Amatngalim, Gimano D.; Bracher, Franz; Mutius, Erika von; Smits, Hermelijn H. und Hiemstra, Pieter S.
(2018):
Farm dust reduces viral load in human bronchial epithelial cells by increasing barrier function and antiviral responses.
In: Journal of Allergy and Clinical Immunology, Bd. 141, Nr. 5: S. 1949-1952
Voegerl, Katharina; Ong, Nghia; Senger, Johanna; Herp, Daniel; Schmidtkunz, Karin; Marek, Martin; Müller, Martin; Bartel, Karin; Shaik, Tajith B.; Porter, Nicholas J.; Robaa, Dina; Christianson, David W.; Romier, Christophe; Sippl, Wolfgang; Jung, Manfred und Bracher, Franz
(2019):
Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors.
In: Journal of Medicinal Chemistry, Bd. 62, Nr. 3: S. 1138-1166
Wagner, I.; Geh, K. J.; Hubert, M.; Winter, G.; Weber, K.; Classen, J.; Klinger, C. und Müller, R. S.
(2017):
Preliminary evaluation of cytosine-phosphate-guanine oligodeoxynucleotides bound to gelatine nanoparticles as immunotherapy for canine atopic dermatitis.
In: Veterinary Record, Bd. 181, Nr. 5
Wang, Pengyu; Klassmueller, Thomas; Karg, Cornelia A.; Kretschmer, Maibritt; Zahler, Stefan; Braig, Simone; Bracher, Franz; Vollmar, Angelika M. und Moser, Simone
(2022):
Using the yeast three-hybrid system for the identification of small molecule-protein interactions with the example of ethinylestradiol.
In: Biological Chemistry, Bd. 403, Nr. 4: S. 421-431
Wang, Jinhua; Wicher, Barbara; Mendez-Ardoy, Alejandro; Li, Xuesong; Pecastaings, Gilles; Buffeteau, Thierry; Bassani, Dario M.; Maurizot, Victor und Huc, Ivan
(2021):
Loading Linear Arrays of Cu-II Inside Aromatic Amide Helices.
In: Angewandte Chemie-International Edition, Bd. 60, Nr. 34: S. 18461-18466
Wang, Shanshan; Li, Chengyi; Qian, Min; Jiang, Huiling; Shi, Wei; Chen, Jian; Lächelt, Ulrich; Wagner, Ernst; Lu, Weiyue; Wang, Yi und Huang, Rongqin
(2017):
Augmented glioma-targeted theranostics using multifunctional polymer-coated carbon nanodots.
In: Biomaterials, Bd. 141: S. 29-39
Wang, Shuaijun; Crevenna, Alvaro H.; Ugur, Ilke; Marion, Antoine; Antes, Iris; Kazmaier, Uli; Hoyer, Maria; Lamb, Don C.; Gegenfurtner, Florian; Kliesmetes, Zane; Ziegenhain, Christoph; Enard, Wolfgang; Vollmar, Angelika und Zahler, Stefan
(2019):
Actin stabilizing compounds show specific biological effects due to their binding mode.
In: Scientific Reports, Bd. 9, 9731
[PDF, 5MB]
Wang, Shuaijun; Gegenfurtner, Florian A.; Crevenna, Alvaro H.; Ziegenhain, Christoph; Kliesmete, Zane; Enard, Wolfgang; Müller, Rolf; Vollmar, Angelika M.; Schneider, Sabine und Zahler, Stefan
(2019):
Chivosazole A Modulates Protein Protein Interactions of Actin.
In: Journal of Natural Products, Bd. 82, Nr. 7: S. 1961-1970
Wang, Shuaijun; Meixner, Maximilian; Yu, Lushuang; Zhuo, Ling; Karmann, Lisa; Kazmaier, Uli; Vollmar, Angelika M.; Antes, Iris und Zahler, Stefan
(2021):
Turning the Actin Nucleating Compound Miuraenamide into Nucleation Inhibitors.
In: ACS Omega, Bd. 6, Nr. 34: S. 22165-22172
Wang, Yanfang; Zhang, Quanli; Gao, Zhaojia; Xin, Shan; Zhao, Yando; Zhang, Kai; Shi, Run und Bao, Xuanwen
(2019):
A novel 4-gene signature for overall survival prediction in lung adenocarcinoma patients with lymph node metastasis.
In: Cancer Cell International, Bd. 19, 100
Wein, Thomas; Höfner, Georg; Rappenglück, Sebastian; Sichler, Sonja; Niessen, Karin V.; Seeger, Thomas; Worek, Franz; Thiermann, Horst und Wanner, Klaus T.
(2018):
Searching for putative binding sites of the bispyridinium compound MB327 in the nicotinic acetylcholine receptor.
In: Toxicology Letters, Bd. 293: S. 184-189
Wein, Thomas; Wanner, Klaus T.; Rappenglueck, Sebastian; Sichler, Sonja; Niessen, Karin; Seeger, Thomas; Worek, Franz und Thiermann, Horst
(2019):
New Resensitizers for the Nicotinic Acetylcholine Receptor by Ligand-Based Pharmacophore Modeling.
In: Current Computer-Aided Drug Design, Bd. 15, Nr. 1: S. 104-109
Westerhausen, Christoph; Schnitzler, Lukas G.; Wendel, Dominik; Krzyszton, Rafal; Lächelt, Ulrich; Wagner, Ernst; Rädler, Joachim O. und Wixforth, Achim
(2016):
Controllable Acoustic Mixing of Fluids in Microchannels for the Fabrication of Therapeutic Nanoparticles.
In: Micromachines, Bd. 7, Nr. 9, 150
[PDF, 4MB]
Willems, Sabine; Marschner, Julian A.; Kilu, Whitney; Faudone, Giuseppe; Busch, Romy; Duensing‐Kropp, Silke; Heering, Jan und Merk, Daniel
(30. Juni 2022):
Nurr1 Modulation Mediates Neuroprotective Effects of Statins.
In: Advanced Science, Bd. 9, Nr. 18
[PDF, 4MB]
Woortman, Dirk Volker; Jürgens, Sophie; Untergehrer, Martin; Rechenberger, Julia; Fuchs, Monika; Mehlmer, Norbert; Qoura, Farah; Eckel, Georg; Stoehr, Michael; Osswald, Patrick; Le Clercq, Patrick; Hintermann, Lukas; Weuster-Botz, Dirk; Bracher, Franz und Brueck, Thomas
(2020):
Greener aromatic antioxidants for aviation and beyond.
In: Sustainable Energy & Fuels, Bd. 4, Nr. 5: S. 2153-2163
Wurzlbauer, Anne; Rueben, Katharina; Guerdal, Ece; Chaikuad, Apirat; Knapp, Stefan; Sippl, Wolfgang; Becker, Walter und Bracher, Franz
(2020):
How to Separate Kinase Inhibition from Undesired Monoamine Oxidase A Inhibition-The Development of the DYRK1A Inhibitor AnnH75 from the Alkaloid Harmine.
In: Molecules, Bd. 25, Nr. 24, 5962
Wuttke, Stefan; Zimpel, Andreas; Bein, Thomas; Braig, Simone; Stoiber, Katharina; Vollmar, Angelika; Müller, Dominik; Haastert-Talini, Kirsten; Schaeske, Jörn; Stiesch, Meike; Zahn, Gesa; Mohmeyer, Alexander; Behrens, Peter; Eickelberg, Oliver; Bölükbas, Deniz A. und Meiners, Silke
(2017):
Validating Metal-Organic Framework Nanoparticles for Their Nanosafety in Diverse Biomedical Applications.
In: Advanced Healthcare Materials, Bd. 6, Nr. 2, 1600818
Xie, Ying; Hang, Yu; Wang, Yazhe; Sleightholm, Richard; Prajapati, Dipakkumar R.; Bader, Johannes; Yu, Ao; Tang, Weimin; Jaramillo, Lee; Li, Jing; Singh, Rakesh K. und Oupicky, David
(2020):
Stromal Modulation and Treatment of Metastatic Pancreatic Cancer with Local Intraperitoneal Triple miRNA/siRNA Nanotherapy.
In: ACS Nano, Bd. 14, Nr. 1: S. 255-271
Xie, Yuran; Kim, Na Hyung; Nadithe, Venkatareddy; Schalk, Dana; Thakur, Archana; Kılıç, Ayşe; Lum, Lawrence G.; Bassett, David J. P. und Merkel, Olivia M.
(2016):
Targeted delivery of siRNA to activated T cells via transferrin-polyethylenimine (Tf-PEI) as a potential therapy of asthma.
In: Journal of Controlled Release, Bd. 229: S. 120-129
Yazdi, Mina; Pöhmerer, Jana; Hasanzadeh Kafshgari, Morteza; Seidl, Johanna; Grau, Melina; Höhn, Miriam; Vetter, Victoria; Hoch, Cosima C.; Wollenberg, Barbara; Multhoff, Gabriele; Bashiri Dezfouli, Ali und Wagner, Ernst ORCID: https://orcid.org/0000-0001-8413-0934
(2024):
In Vivo Endothelial Cell Gene Silencing by siRNA‐LNPs Tuned with Lipoamino Bundle Chemical and Ligand Targeting.
In: Small
[PDF, 6MB]
Yoneda, Saki; Niederleitner, Bertram; Wiggenhorn, Michael; Koga, Hiroki; Totoki, Shinichiro; Krayukhina, Elena; Friess, Wolfgang und Uchiyama, Susumu
(2019):
Quantitative Laser Diffraction for Quantification of Protein Aggregates: Comparison With Resonant Mass Measurement, Nanoparticle Tracking Analysis, Flow Imaging, and Light Obscuration.
In: Journal of Pharmaceutical Sciences, Bd. 108, Nr. 1: S. 755-762
Yordanova, Yordanka; Vanderlinden, Willem; Stoll, Raphael; Rüdiger, Daniel; Tosstorff, Andreas; Zaremba, Wolfgang; Winter, Gerhard; Zahler, Stefan und Friess, Wolfgang
(2018):
Zn2+-triggered self-assembly of Gonadorelin [6-D-Phe] to produce nanostructures and fibrils.
In: Scientific Reports, Bd. 8, 11280
[PDF, 3MB]
Yuan, Yu; Jaslan, Dawid; Rahman, Taufiq; Bolsover, Stephen R.; Arige, Vikas; Wagner, Larry E.; Abrahamian, Carla; Tang, Rachel; Keller, Marco; Hartmann, Jonas; Rosato, Anna S.; Weiden, Eva-Maria; Bracher, Franz; Yule, David I.; Grimm, Christian und Patel, Sandip
(2022):
Segregated cation flux by TPC2 biases Ca2+ signaling through lysosomes.
In: Nature Communications, Bd. 13, Nr. 1, 4481
Yuan, Yu; Kilpatrick, Bethan S.; Gerndt, Susanne; Bracher, Franz; Grimm, Christian; Schapira, Anthony H. und Patel, Sandip
(2021):
The lysosomotrope GPN mobilises Ca2+ from acidic organelles.
In: Journal of Cell Science, Bd. 134, Nr. 6, jcs256578
Zareba, Paula; Gryzlo, Beata; Malawska, Katarzyna; Salat, Kinga; Höfner, Georg C.; Nowaczyk, Alicja; Fijalkowski, Lukasz; Rapacz, Anna; Podkowa, Adrian; Furgala, Anna; Zmudzki, Pawel; Wanner, Klaus T.; Malawska, Barbara und Kulig, Katarzyna
(2020):
Novel mouse GABA uptake inhibitors with enhanced inhibitory activity toward mGAT3/4 and their effect on pain threshold in mice.
In: European Journal of Medicinal Chemistry, Bd. 188, 111920
Zareba, Paula; Salat, Kinga; Höfner, Georg C.; Latka, Kamil; Bajda, Marek; Latacz, Gniewomir; Kotniewicz, Krzysztof; Rapacz, Anna; Podkowa, Adrian; Maj, Maciej; Jozwiak, Krzysztof; Filipek, Barbara; Wanner, Klaus T.; Malawska, Barbara und Kulig, Katarzyna
(2021):
Development of tricyclic N-benzyl-4-hydroxybutanamide derivatives as inhibitors of GABA transporters mGAT1-4 with anticonvulsant, antinociceptive, and antidepressant activity.
In: European Journal of Medicinal Chemistry, Bd. 221, 113512
Zeisel, Lukas; Felber, Jan G.; Scholzen, Karoline C.; Poczka, Lena; Cheff, Dorian; Maier, Martin S.; Cheng, Qing; Shen, Min; Hall, Matthew D.; Arner, Elias S. J.; Thorn-Seshold, Julia und Thorn-Seshold, Oliver
(2022):
Selective cellular probes for mammalian thioredoxin reductase TrxR1: Rational design of RX1, a modular 1,2-thiaselenane redox probe.
In: Chem, Bd. 8, Nr. 5: S. 1493-1517
Zhang, S.; Ulrich, M.; Gromnicka, A.; Havlíček, L.; Kryštof, V.; Jorda, R.; Strnad, M.; Vollmar, A. M. und Zahler, S.
(2016):
Anti-angiogenic effects of novel cyclin-dependent kinase inhibitors with a pyrazolo[4,3-d]pyrimidine scaffold.
In: British Journal of Pharmacology, Bd. 173, Nr. 17: S. 2645-2656
Zhang, Wei; Müller, Katharina; Kessel, Eva; Reinhard, Sören; He, Dongsheng; Klein, Philipp M.; Höhn, Miriam; Rödl, Wolfgang; Kempter, Susanne und Wagner, Ernst
(2016):
Targeted siRNA Delivery Using a Lipo-Oligoaminoamide Nanocore with an Influenza Peptide and Transferrin Shell.
In: Advanced Healthcare Materials, Bd. 5, Nr. 12: S. 1493-1504
Zhang, Xiaohan; Chytil, Petr; Etrych, Tomas; Liu, Weiwei; Rodrigues, Leticia; Winter, Gerhard; Filippov, Sergey K. und Papadakis, Christine M.
(2018):
Binding of HSA to Macromolecular rho HPMA Based Nanoparticles for Drug Delivery: An Investigation Using Fluorescence Methods.
In: Langmuir, Bd. 34, Nr. 27: S. 7998-8006
Zhong, Yulong; Kauffmann, Brice; Xu, Wenwu; Lu, Zhong-Lin; Ferrand, Yann; Huc, Ivan; Zeng, Xiao Cheng; Liu, Rui und Gong, Bing
(2020):
Multiturn Hollow Helices: Synthesis and Folding of Long Aromatic Oligoamides.
In: Organic Letters, Bd. 22, Nr. 17: S. 6938-6942
Ziach, Krzysztof; Chollet, Celine; Parissi, Vincent; Prabhakaran, Panchami; Marchivie, Mathieu; Corvaglia, Valentina; Bose, Partha Pratim; Laxmi-Reddy, Katta; Godde, Frederic; Schmitter, Jean-Marie; Chaignepain, Stephane; Pourquier, Philippe und Huc, Ivan
(2018):
Single helically folded aromatic oligoamides that mimic the charge surface of double-stranded B-DNA.
In: Nature Chemistry, Bd. 10, Nr. 5: S. 511-518
Zimmermann, Christoph M.; Baldassi, Domizia; Chan, Karen; Adams, Nathan B. P.; Neumann, Alina; Porras-Gonzalez, Diana Leidy; Wei, Xin; Kneidinger, Nikolaus; Stoleriu, Mircea Gabriel; Burgstaller, Gerald; Witzigmann, Dominik; Luciani, Paola und Merkel, Olivia M.
(2022):
Spray drying siRNA-lipid nanoparticles for dry powder pulmonary delivery.
In: Journal of Controlled Release, Bd. 351: S. 137-150
Zisis, Themistoklis; Brueckner, David B.; Brandstaetter, Tom; Siow, Wei Xiong; d'Alessandro, Joseph; Vollmar, Angelika M.; Broedersz, Chase P. und Zahler, Stefan
(2022):
Disentangling cadherin-mediated cell-cell interactions in collective cancer cell migration.
In: Biophysical Journal, Bd. 121, Nr. 1: S. 44-60
Zisis, Themistoklis; Schwarz, Jan; Balles, Miriam; Kretschmer, Maibritt; Nemethova, Maria; Chait, Remy; Hauschild, Robert; Lange, Janina; Guet, Calin; Sixt, Michael und Zahler, Stefan
(2021):
Sequential and Switchable Patterning for Studying Cellular Processes under Spatiotemporal Control.
In: ACS Applied Materials & Interfaces, Bd. 13, Nr. 30: S. 35545-35560
Zwillinger, Marton; Reddy, Post Sai; Wicher, Barbara; Mandal, Pradeep K.; Csekei, Marton; Fischer, Lucile; Kotschy, Andras und Huc, Ivan
(2020):
Aromatic Foldamer Helices as alpha-Helix Extended Surface Mimetics.
In: Chemistry-A European Journal, Bd. 26, Nr. 72: S. 17366-17370
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