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Tsiamantas, Christos; Kwon, Sunbum; Douat, Celine; Huc, Ivan; Suga, Hiroaki (2019): Optimizing aromatic oligoamide foldamer side-chains for ribosomal translation initiation. In: Chemical Communications, Vol. 55, No. 51: pp. 7366-7369
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Abstract

The tolerance of ribosomal peptide translation for helical aromatic oligoamide foldamers appended as initiators has been investigated. Small cationic foldamer side-chains were shown to expand the range of foldamer-peptide hybrids that can be produced by the ribosome to more rigid sequences.