Data on specificity of [F-18]GE180 uptake for TSPO expression in rodent brain and myocardium

Deussing, Maximilian; Blume, Tanja; Vomacka, Lena; Mahler, Christoph; Focke, Carola; Todica, Andrei; Unterrainer, Marcus; Albert, Nathalie L. ; Lindner, Simon; Ungern-Sternberg, Barbara von; Baumann, Karlheinz; Zwergal, Andreas; Bartenstein, Peter; Herms, Jochen; Rominger, Axel und Brendel, Matthias (2018): Data on specificity of [F-18]GE180 uptake for TSPO expression in rodent brain and myocardium. In: Data in Brief, Bd. 19: S. 331-336

Abstract

Data in this article show radioligand uptake (to gamma counter and positron-emission-tomography) as well as polymerase chain reaction analyses of 18 kDa translocator protein (TSPO) quantification. We confirmed specificity of [F-18]GE180 binding of rodent brain and myocardium by blocking experiments with prior application of non-radioactive GE180, using dynamic in vivo positron emission-tomography and ex vivo gamma counter measurements. Expression of TSPO was compared between rodent brain and myocardium by quantitative polymerase chain reaction.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Medizin > Munich Cluster for Systems Neurology (SyNergy)
• Themengebiete: 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 2352-3409
• Sprache: Englisch
• DFG: Gefördert durch die Deutsche Forschungsgemeinschaft (DFG) - 390857198