A short and divergent route to 2-alkenyl-4-quinolones

Lohrer, Bernhard und Bracher, Franz (2018): A short and divergent route to 2-alkenyl-4-quinolones. In: Tetrahedron Letters, Bd. 59, Nr. 40: S. 3632-3635

Abstract

2-alkenyl-4-quinolones were accessed via a high-yielding, three-step synthesis starting from 2-methyl-4-quinolones using a one-pot phosphorylation-olefination sequence as the key step and SEM as a convenient protecting group. This protocol tolerates various functional groups and gives the target olefins with complete (E)-selectivity.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Chemie und Pharmazie > Department für Pharmazie - Zentrum für Pharmaforschung
• Themengebiete: 500 Naturwissenschaften und Mathematik > 540 Chemie
• ISSN: 0040-4039
• Sprache: Englisch