Optimizing aromatic oligoamide foldamer side-chains for ribosomal translation initiation

Tsiamantas, Christos; Kwon, Sunbum; Douat, Celine; Huc, Ivan und Suga, Hiroaki (2019): Optimizing aromatic oligoamide foldamer side-chains for ribosomal translation initiation. In: Chemical Communications, Bd. 55, Nr. 51: S. 7366-7369

Abstract

The tolerance of ribosomal peptide translation for helical aromatic oligoamide foldamers appended as initiators has been investigated. Small cationic foldamer side-chains were shown to expand the range of foldamer-peptide hybrids that can be produced by the ribosome to more rigid sequences.

• Dokumententyp: Zeitschriftenartikel
• Fakultät: Chemie und Pharmazie > Department für Pharmazie - Zentrum für Pharmaforschung
• Themengebiete: 500 Naturwissenschaften und Mathematik > 540 Chemie
• ISSN: 1359-7345
• Sprache: Englisch