Anzahl der Publikationen: 49
2022
Stirm, Michael; Fonteyne, Lina Marie; Shashikadze, Bachuki; Stoeckl, Jan B.; Kurome, Mayuko; Kessler, Barbara; Zakhartchenko, Valeri; Kemter, Elisabeth; Blum, Helmut; Arnold, Georg J.; Matiasek, Kaspar; Wanke, Ruediger; Wurst, Wolfgang; Nagashima, Hiroshi; Knieling, Ferdinand; Walter, Maggie C.; Kupatt, Christian; Froehlich, Thomas; Klymiuk, Nikolai; Blutke, Andreas und Wolf, Eckhard
(2022):
Pig models for Duchenne muscular dystrophy-from disease mechanisms to validation of new diagnostic and therapeutic concepts.
In: Neuromuscular Disorders, Bd. 32, Nr. 7: S. 543-556
2021
Flenkenthaler, Florian; Laendstroem, Erik; Shashikadze, Bachuki; Backman, Mattias; Blutke, Andreas; Philippou-Massier, Julia; Renner, Simone; Hrabe de Angelis, Martin; Wanke, Ruediger; Blum, Helmut; Arnold, Georg J.; Wolf, Eckhard und Froehlich, Thomas
(23. November 2021):
Differential Effects of Insulin-Deficient Diabetes Mellitus on Visceral vs. Subcutaneous Adipose Tissue-Multi-omics Insights From the Munich MIDY Pig Model.
In: Frontiers in Medicine, Bd. 8, 751277
[PDF, 2MB]
Stirm, Michael; Fonteyne, Lina Marie; Shashikadze, Bachuki; Lindner, Magdalena; Chirivi, Maila; Lange, Andreas; Kaufhold, Clara; Mayer, Christian; Medugorac, Ivica; Kessler, Barbara; Kurome, Mayuko; Zakhartchenko, Valeri; Hinrichs, Arne; Kemter, Elisabeth; Krause, Sabine; Wanke, Rüdiger; Arnold, Georg J.; Wess, Gerhard; Nagashima, Hiroshi; de Angelis, Marin Hrabe; Flenkenthaler, Florian; Kobelke, Levin Arne; Bearzi, Claudia; Rizzi, Roberto; Bähr, Andreas; Reese, Sven ORCID: https://orcid.org/0000-0002-4605-9791; Matiasek, Kaspar; Walter, Maggie C.; Kupatt, Christian; Ziegler, Sibylle; Bartenstein, Peter; Fröhlich, Thomas; Klymiuk, Nikolai; Blutke, Andreas und Wolf, Eckhard
(19. November 2021):
A scalable, clinically severe pig model for Duchenne muscular dystrophy.
In: Disease Models & Mechanisms, Bd. 14, Nr. 12
[PDF, 3MB]
Stirm, Michael; Fonteyne, Lina Marie; Shashikadze, Bachuki; Lindner, Magdalena; Chirivi, Maila; Lange, Andreas; Kaufhold, Clara; Mayer, Christian; Medugorac, Ivica; Kessler, Barbara; Kurome, Mayuko; Zakhartchenko, Valeri; Hinrichs, Arne; Kemter, Elisabeth; Krause, Sabine; Wanke, Rudiger; Arnold, Georg J.; Wess, Gerhard; Nagashima, Hiroshi; de Angelis, Martin Hrabe; Flenkenthaler, Florian; Kobelke, Levin Arne; Bearzi, Claudia; Rizzi, Roberto; Baehr, Andrea; Reese, Sven; Matiasek, Kaspar; Walter, Maggie C.; Kupatt, Christian; Ziegler, Sibylle; Bartenstein, Peter; Froehlich, Thomas; Klymiuk, Nikolai; Blutke, Andreas und Wolf, Eckhard
(2021):
A scalable, clinically severe pig model for Duchenne muscular dystrophy.
In: Disease Models & Mechanisms, Bd. 14, Nr. 12, dmm049285
Trotter, Benjamin; Wilde, Magdalena; Brehm, Julian; Dafni, Evdokia; Aliu, Arlinda; Arnold, Georg J.; Fröhlich, Thomas und Laforsch, Christian
(2021):
Long-term exposure of Daphnia magna to polystyrene microplastic (PS-MP) leads to alterations of the proteome, morphology and life-history.
In: Science of the Total Environment, Bd. 795, 148822
Stöckl, Jan B.; Schmid, Nina; Flenkenthaler, Florian; Drummer, Charis; Behr, Rüdiger; Mayerhofer, Artur; Arnold, Georg J. und Fröhlich, Thomas
(2021):
Age-Related Alterations in the Testicular Proteome of a Non-Human Primate.
In: Cells, Bd. 10, Nr. 6, 1306
2020
Riedel, Evamaria O.; Hinrichs, Arne; Kemter, Elisabeth; Dahlhoff, Maik; Backman, Mattias; Rathkolb, Birgit; Prehn, Cornelia; Adamski, Jerzy; Renner, Simone; Blutke, Andreas; Hrabe de Angelis, Martin; Bidlingmaier, Martin; Schopohl, Jochen; Arnold, Georg J.; Fröhlich, Thomas und Wolf, Eckhard
(2020):
Functional changes of the liver in the absence of growth hormone (GH) action - Proteomic and metabolomic insights from a GH receptor deficient pig model.
In: Molecular Metabolism, Bd. 36, 100978
Tamiyakul, Hathaichanok; Kemter, Elisabeth; Kösters, Miwako; Ebner, Stefanie; Blutke, Andreas; Klymiuk, Nikolai; Flenkenthaler, Florian; Wolf, Eckhard; Arnold, Georg J. und Fröhlich, Thomas
(2020):
Progressive Proteome Changes in the Myocardium of a Pig Model for Duchenne Muscular Dystrophy.
In: Iscience, Bd. 23, Nr. 9, 101516
Schmid, Nina; Missel, Annika; Petkov, Stoyan; Stöckl, Jan B.; Flenkenthaler, Florian; Arnold, Georg J.; Fröhlich, Thomas; Behr, Rüdiger und Mayerhofer, Artur
(2020):
A translational cellular model for the study of peritubular cells of the testis.
In: Reproduction, Bd. 160, Nr. 2: S. 259-268
Gegenfurtner, Katrin; Fröhlich, Thomas; Flenkenthaler, Florian; Koesters, Miwako; Fritz, Sebastien; Desnoes, Olivier; Le Bourhis, Daniel; Salvetti, Pascal; Sandra, Olivier; Charpigny, Gilles; Mermillod, Pascal; Lonergan, Patrick; Wolf, Eckhard und Arnold, Georg J.
(2020):
Genetic merit for fertility alters the bovine uterine luminal fluid proteome.
In: Biology of Reproduction, Bd. 102, Nr. 3: S. 730-739
Messner, Martina; Schmitt, Sabine; Ardelt, Maximilian A.; Fröhlich, Thomas; Müller, Martin; Pein, Helmut; Huber-Cantonati, Petra; Ortler, Carina; König, Lars M.; Zobel, Lena; Koeberle, Andreas; Arnold, Georg J.; Rothenfusser, Simon; Kiemer, Alexandra K.; Gerbes, Alexander L.; Zischka, Hans; Vollmar, Angelika M. und Pachmayr, Johanna
(2020):
Metabolic implication of tigecycline as an efficacious second-line treatment for sorafenib-resistant hepatocellular carcinoma.
In: FASEB Journal, Bd. 34, Nr. 9: S. 11860-11882
Stöckl, Jan B.; Schmid, Nina; Flenkenthaler, Florian; Drummer, Charis; Behr, Rüdiger; Mayerhofer, Artur; Arnold, Georg J. und Fröhlich, Thomas
(2020):
Proteomic Insights into Senescence of Testicular Peritubular Cells from a Nonhuman Primate Model.
In: Cells, Bd. 9, Nr. 11, 2498
Hinrichs, Arne; Riedel, Evamaria O.; Klymiuk, Nikolai; Blutke, Andreas; Kemter, Elisabeth; Laengin, Matthias; Dahlhoff, Maik; Kessler, Barbara; Kurome, Mayuko; Zakhartchenko, Valeri; Jemiller, Eva-Maria; Ayares, David; Bidlingmaier, Martin; Flenkenthaler, Florian; Hrabe de Angelis, Martin; Arnold, Georg J.; Reichart, Bruno; Fröhlich, Thomas und Wolf, Eckhard
(2020):
Growth hormone receptor knockout to reduce the size of donor pigs for preclinical xenotransplantation studies.
In: Xenotransplantation, Bd. 28, Nr. 2, e12664
2019
Schmid, Nina; Flenkenthaler, Florian; Stöckl, Jan B.; Dietrich, Kim-Gwendolyn; Koehn, Frank M.; Schwarzer, J. Ullrich; Kunz, Lars; Luckner, Manja; Wanner, Gerhard; Arnold, Georg J.; Fröhlich, Thomas und Mayerhofer, Artur
(2019):
Insights into replicative senescence of human testicular peritubular cells.
In: Scientific Reports, Bd. 9, 15052
[PDF, 7MB]
Sommer, Ann-Katrin; Falcenberg, Mathias; Ljepoja, Bojan; Fröhlich, Thomas; Arnold, Georg J.; Wagner, Ernst und Roidl, Andreas
(2019):
Downregulation of GRK5 hampers the migration of breast cancer cells.
In: Scientific Reports, Bd. 9, 15548
[PDF, 5MB]
Ardelt, Maximilian A.; Fröhlich, Thomas; Martini, Emanuele; Müller, Martin; Kanitz, Veronika; Atzberger, Carina; Cantonati, Petra; Messner, Martina; Posselt, Laura; Lehr, Thorsten; Wojtyniak, Jan-Georg; Ulrich, Melanie; Arnold, Georg J.; König, Lars; Parazzoli, Dario; Zahler, Stefan; Rothenfusser, Simon; Mayr, Doris; Gerbes, Alexander; Scita, Giorgio; Vollmar, Angelika M. und Pachmayr, Johanna
(2019):
Inhibition of Cyclin-Dependent Kinase 5: A Strategy to Improve Sorafenib Response in Hepatocellular Carcinoma Therapy.
In: Hepatology, Bd. 69, Nr. 1: S. 376-393
Papp, Sophie M.; Fröhlich, Thomas; Radefeld, Karina; Havlicek, Viterslav; Koesters, Miwako; Yu, Hans; Mayrhofer, Corina; Brem, Gottfried; Arnold, Georg J. und Besenfelder, Urban
(2019):
A novel approach to study the bovine oviductal fluid proteome using transvaginal endoscopy.
In: Theriogenology, Bd. 132: S. 53-61
Backman, Mattias; Flenkenthaler, Florian; Blutke, Andreas; Dahlhoff, Maik; Laendstroem, Erik; Renner, Simone; Philippou-Massier, Julia; Krebs, Stefan; Rathkolb, Birgit; Prehn, Cornelia; Grzybek, Michal; Coskun, Uenal; Rothe, Michael; Adamski, Jerzy; de Angelis, Martin Hrabe; Wanke, Rüdiger; Fröhlich, Thomas; Arnold, Georg J.; Blum, Helmut und Wolf, Eckhard
(2019):
Multi-omics insights into functional alterations of the liver in insulin-deficient diabetes mellitus.
In: Molecular Metabolism, Bd. 26: S. 30-44
Gegenfurtner, Katrin; Fröhlich, Thomas; Koesters, Miwako; Mermillod, Pascal; Locatelli, Yann; Fritz, Sebastien; Salvetti, P.; Forde, Niamh; Lonergan, Patrick; Wolf, Eckhard und Arnold, Georg J.
(2019):
Influence of metabolic status and genetic merit for fertility on proteomic composition of bovine oviduct fluid.
In: Biology of Reproduction, Bd. 101, Nr. 5: S. 893-905
Pfeiler, Susanne; Thakur, Manovriti; Grünauer, Petra; Megens, Remco T. A.; Joshi, Urjita; Coletti, Raffaele; Samara, Verena; Müller-Stoy, Geraldine; Ishikawa-Ankerhold, Hellen; Stark, Konstantin; Klingl, Andreas; Fröhlich, Thomas; Arnold, Georg J.; Woermann, Sonja; Bruns, Christiane J.; Alguel, Hana; Weber, Christian; Massberg, Steffen und Engelmann, Bernd
(2019):
CD36-triggered cell invasion and persistent tissue colonization by tumor microvesicles during metastasis.
In: Faseb Journal, Bd. 33, Nr. 2: S. 1860-1872
Ye, Yao; Kuhn, Christina; Koesters, Miwako; Arnold, Georg J.; Ishikawa-Ankerhold, Hellen; Schulz, Christian; Rogenhofer, Nina; Thaler, Christian J.; Mahner, Sven; Fröhlich, Thomas; Jeschke, Udo und Schönfeldt, Viktoria von
(2019):
Anti alpha-enolase antibody is a novel autoimmune biomarker for unexplained recurrent miscarriages.
In: Ebiomedicine, Bd. 41: S. 610-622
2018
Ljepoja, Bojan; Garcia-Roman, Jonathan; Sommer, Ann-Katrin; Frohlich, Thomas; Arnold, Georg J.; Wagner, Ernst und Roidl, Andreas
(2018):
A proteomic analysis of an in vitro knock-out of miR-200c.
In: Scientific Reports, Bd. 8, 6927
[PDF, 3MB]
Walenta, Lena; Fleck, David; Fröhlich, Thomas; Eysmondt, Hendrik von; Arnold, Georg J.; Spehr, Jennifer; Schwarzer, J. Ullrich; Köhn, Frank-Michael; Spehr, Marc und Mayerhofer, Artur
(2018):
ATP-mediated Events in Peritubular Cells Contribute to Sterile Testicular Inflammation.
In: Scientific Reports, Bd. 8, 1431
[PDF, 2MB]
2017
Ayoubian, Hiresh; Fröhlich, Thomas; Pogodski, Dagmar; Flatley, Andrew; Kremmer, Elisabeth; Schepers, Aloys; Feederle, Regina; Arnold, Georg J. und Grässer, Friedrich A.
(2017):
Antibodies against the mono-methylated arginine-glycine repeat (MMA-RG) of the Epstein-Barr virus nuclear antigen 2 (EBNA2) identify potential cellular proteins targeted in viral transformation.
In: Journal of General Virology, Bd. 98, Nr. 8: S. 2128-2142
Blutke, Andreas; Renner, Simone; Flenkenthaler, Florian; Backman, Mattias; Häsner, Serena; Kemter, Elisabeth; Ländström, Erik; Braun-Reichhart, Christina; Albl, Barbara; Streckel, Elisabeth; Rathkolb, Birgit; Prehn, Cornelia; Palladini, Alessandra; Grzybek, Michal; Krebs, Stefan; Bauersachs, Stefan; Bähr, Andrea; Brühschwein, Andreas ORCID: https://orcid.org/0000-0002-7833-8031; Deeg, Cornelia A.; Monte, Erica de; Dmochewitz, Michaela; Eberle, Caroline; Emrich, Daniela; Fux, Robert; Groth, Frauke; Gumbert, Sophie; Heitmann, Antonia; Hinrichs, Arne; Kessler, Barbara; Kurome, Mayuko; Leipig-Rudolph, Miriam; Matiasek, Kaspar; Öztürk, Hazal; Otzdorff, Christiane; Reichenbach, Myriam; Reichenbach, Horst Dieter; Rieger, Alexandra; Rieseberg, Birte; Rosati, Marco; Saucedo, Manuel Nicolas; Schleicher, Anna; Schneider, Marlon R.; Simmet, Kilian; Steinmetz, Judith; Übel, Nicole; Zehetmaier, Patrizia; Jung, Andreas; Adamski, Jerzy; Coskun, Ünal; Hrabe de Angelis, Martin; Simmet, Christian; Ritzmann, Mathias; Meyer-Lindenberg, Andrea; Blum, Helmut; Arnold, Georg J.; Fröhlich, Thomas; Wanke, Rüdiger und Wolf, Eckhard
(2017):
The Munich MIDY Pig Biobank - A unique resource for studying organ crosstalk in diabetes.
In: Molecular Metabolism, Bd. 6, Nr. 8: S. 931-940
Blaj, Cristina; Bringmann, Agnes; Schmidt, Eva Marina; Urbischek, Manuela; Lamprecht, Sebastian; Fröhlich, Thomas; Arnold, Georg J.; Krebs, Stefan; Blum, Helmut; Hermeking, Heiko; Jung, Andreas; Kirchner, Thomas und Horst, David
(2017):
ADNP Is a Therapeutically Inducible Repressor of WNT Signaling in Colorectal Cancer.
In: Clinical Cancer Research, Bd. 23, Nr. 11: S. 2769-2780
2016
Trapphoff, Tom; Heiligentag, Martyna; Simon, Jenny; Staubach, Nora; Seidel, Thorsten; Otte, Kathrin; Fröhlich, Thomas; Arnold, Georg J. und Eichenlaub-Ritter, Ursula
(2016):
Improved cryotolerance and developmental potential of in vitro and in vivo matured mouse oocytes by supplementing with a glutathione donor prior to vitrification.
In: Molecular Human Reproduction, Bd. 22, Nr. 12: S. 867-881
Kovacs, Izabella; Holzmeister, Christian; Wirtz, Markus; Geerlof, Arie; Fröhlich, Thomas; Römling, Gaby; Kuruthukulangarakoola, Gitto T.; Linster, Eric; Hell, Rüdiger; Arnold, Georg J.; Durner, Joerg und Lindermayr, Christian
(2016):
ROS-Mediated Inhibition of S-nitrosoglutathione Reductase Contributes to the Activation of Anti-oxidative Mechanisms.
In: Frontiers in Plant Science, Bd. 7, 1669
[PDF, 3MB]
Fröhlich, Thomas; Kemter, Elisabeth; Flenkenthaler, Florian; Klymiuk, Nikolai; Otte, Kathrin A.; Blutke, Andreas; Krause, Sabine; Walter, Maggie C.; Wanke, Rüdiger; Wolf, Eckhard und Arnold, Georg J.
(2016):
Progressive muscle proteome changes in a clinically relevant pig model of Duchenne muscular dystrophy.
In: Scientific Reports, Bd. 6, 33362
[PDF, 2MB]
Herzog, Julia; Ehrlich, Sandra M.; Pfitzer, Lisa; Liebl, Johanna; Fröhlich, Thomas; Arnold, Georg J.; Mikulits, Wolfgang; Haider, Christine; Vollmar, Angelika M. und Zahler, Stefan
(2016):
Cyclin-dependent kinase 5 stabilizes hypoxia-inducible factor-1 alpha: a novel approach for inhibiting angiogenesis in hepatocellular carcinoma.
In: Oncotarget, Bd. 7, Nr. 19: S. 27108-27121
2014
2013
2011
2010
Habermann, Felix A.; Matthiesen, Marieke; Reichenbach, Horst-Dieter; Zakhartchenko, Valeri; Reichenbach, M.; Arnold, Georg J.; Demant, M. und Wolf, E.
(2010):
In vitro studies on the developmental competence of oocytes from heifers, young and old cows.
43. Jahrestagung Physiologie u. Pathologie der Fortpflanzung, gleichzeitig 35. Veterinär-Humanmedizinische Gemeinschaftstagung, München, Deutschland, 24. – 26. Februar 2010.
Reproduction in domestic animals / Supplement.
Bd. 45, Nr. 1
S. 17-18
Matthiesen, Marieke; Reichenbach, Horst-Dieter; Habermann, Felix A.; Zakhartchenko, Valeri; Reichenbach, M.; Arnold, Georg J.; Demant, M. und Wolf, E.
(2010):
Maturation and developmental competence of bovine oocytes at different life cycle stages: Ovum Pick Up and functional in vitro studies - preliminary results.
43. Jahrestagung Physiologie u. Pathologie der Fortpflanzung, gleichzeitig 35. Veterinär-Humanmedizinische Gemeinschaftstagung, München, Deutschland, 24. – 26. Februar 2010.
Reproduction in domestic animals / Supplement.
Bd. 45, Nr. 1
S. 31-32
2009
Berendt, Frank J.; Fröhlich, Thomas; Bolbrinker, Patrick; Boelhauve, Marc; Güngör, Tuna; Habermann, Felix A.; Wolf, Eckhard und Arnold, Georg J.
(2009):
Highly sensitive saturation labeling reveals changes in abundance of cell cycle-associated proteins and redox enzyme variants during oocyte maturation in vitro.
In: Proteomics, Bd. 9, Nr. 3: S. 550-564
Fröhlich, Thomas; Berendt, F.; Bolbrinker, Patrick; Habermann, Felix A.; Boelhauve, Marc; Güngör, Tuna; Wolf, E. und Arnold, Georg J.
(2009):
Oocyte maturation in vitro: Proteome alterations analysed by ultra sensitive fluorochrome labeling and nano-ESI-MS/MS.
42. Jahrestagung über Physiologie und Pathologie der Fortpflanzung, gleichzeitig 34. Veterinär-humanmedizinische Gemeinschaftstagung, Leipzig, Deutschland, 26. - 27. Februar 2009.
Reproduction in domestic animals / Supplement.
Bd. 44, Nr. 1
S. 10
Matthiesen, Marieke; Arnold, Georg J.; Demant, M.; Zakhartchenko, Valeri; Habermann, Felix A.; Reichenbach, Horst-Dieter; Reichenbach, M. und Wolf, E.
(2009):
Developmental competence of bovine oocytes obtained from animals at different ages: structural, molecular and functional analyses - preliminary results.
42. Jahrestagung über Physiologie und Pathologie der Fortpflanzung, gleichzeitig 34. Veterinär-humanmedizinische Gemeinschaftstagung, Leipzig, Deutschland, 26. - 27. Februar 2009.
Reproduction in domestic animals / Supplement.
Bd. 44, Nr. 1
S. 23-24
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