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Anzahl der Publikationen: 11
Zeitschriftenartikel
Todorov-Voelgyi, Katalin; Gonzalez-Gallego, Judit; Mueller, Stephan A.; Beaufort, Nathalie; Malik, Rainer; Schifferer, Martina; Todorov, Mihail Ivilinov; Crusius, Dennis; Robinson, Sophie; Schmidt, Andree; Koerbelin, Jakob; Bareyre, Florence; Ertuerk, Ali; Haass, Christian; Simons, Mikael; Paquet, Dominik; Lichtenthaler, Stefan F. und Dichgans, Martin 
ORCID: https://orcid.org/0000-0002-0654-387X
(2024):
Proteomics of mouse brain endothelium uncovers dysregulation of vesicular transport pathways during aging.
In: Nature Aging, Bd. 4, Nr. 4
[PDF, 170MB]
ORCID: https://orcid.org/0000-0002-0654-387X
(2024):
Proteomics of mouse brain endothelium uncovers dysregulation of vesicular transport pathways during aging.
In: Nature Aging, Bd. 4, Nr. 4
[PDF, 170MB]
Beaufort, Nathalie ORCID: https://orcid.org/0000-0002-7088-4206; Ingendahl, Linda; Merdanovic, Melisa; Schmidt, Andree ORCID: https://orcid.org/0000-0002-8254-0777; Podlesainski, David ORCID: https://orcid.org/0000-0002-1111-8042; Richter, Tim ORCID: https://orcid.org/0009-0003-8310-6803; Neumann, Thorben; Kuszner, Michael; Vetter, Ingrid R.; Stege, Patricia; Burston, Steven G. ORCID: https://orcid.org/0000-0003-1848-1853; Filipovic, Anto; Ruiz-Blanco, Yasser B.; Bravo-Rodriguez, Kenny; Mieres-Perez, Joel ORCID: https://orcid.org/0000-0002-7875-0886; Beuck, Christine ORCID: https://orcid.org/0000-0001-7513-7384; Uebel, Stephan ORCID: https://orcid.org/0000-0002-3726-3942; Zobawa, Monika; Schillinger, Jasmin; Malik, Rainer ORCID: https://orcid.org/0000-0001-9212-2520; Todorov-Völgyi, Katalin ORCID: https://orcid.org/0009-0007-8073-9524; Rey, Juliana; Roberti, Annabell; Hagemeier, Birte; Wefers, Benedikt ORCID: https://orcid.org/0000-0002-2492-9389; Müller, Stephan A. ORCID: https://orcid.org/0000-0003-3414-307X; Wurst, Wolfgang ORCID: https://orcid.org/0000-0003-4422-7410; Sanchez-Garcia, Elsa; Zimmermann, Alexander; Hu, Xiao-Yu ORCID: https://orcid.org/0000-0002-9634-315X; Clausen, Tim ORCID: https://orcid.org/0000-0003-1582-6924; Huber, Robert; Lichtenthaler, Stefan F. ORCID: https://orcid.org/0000-0003-2211-2575; Schmuck, Carsten ORCID: https://orcid.org/0000-0001-6062-0357; Giese, Michael; Kaiser, Markus ORCID: https://orcid.org/0000-0002-6540-8520; Ehrmann, Michael ORCID: https://orcid.org/0000-0002-1927-260X und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2024):
Rational correction of pathogenic conformational defects in HTRA1.
In: Nature Communications, Bd. 15, 5944
[PDF, 3MB]
ORCID: https://orcid.org/0000-0002-7088-4206; Ingendahl, Linda; Merdanovic, Melisa; Schmidt, Andree ORCID: https://orcid.org/0000-0002-8254-0777; Podlesainski, David ORCID: https://orcid.org/0000-0002-1111-8042; Richter, Tim ORCID: https://orcid.org/0009-0003-8310-6803; Neumann, Thorben; Kuszner, Michael; Vetter, Ingrid R.; Stege, Patricia; Burston, Steven G. ORCID: https://orcid.org/0000-0003-1848-1853; Filipovic, Anto; Ruiz-Blanco, Yasser B.; Bravo-Rodriguez, Kenny; Mieres-Perez, Joel ORCID: https://orcid.org/0000-0002-7875-0886; Beuck, Christine ORCID: https://orcid.org/0000-0001-7513-7384; Uebel, Stephan ORCID: https://orcid.org/0000-0002-3726-3942; Zobawa, Monika; Schillinger, Jasmin; Malik, Rainer ORCID: https://orcid.org/0000-0001-9212-2520; Todorov-Völgyi, Katalin ORCID: https://orcid.org/0009-0007-8073-9524; Rey, Juliana; Roberti, Annabell; Hagemeier, Birte; Wefers, Benedikt ORCID: https://orcid.org/0000-0002-2492-9389; Müller, Stephan A. ORCID: https://orcid.org/0000-0003-3414-307X; Wurst, Wolfgang ORCID: https://orcid.org/0000-0003-4422-7410; Sanchez-Garcia, Elsa; Zimmermann, Alexander; Hu, Xiao-Yu ORCID: https://orcid.org/0000-0002-9634-315X; Clausen, Tim ORCID: https://orcid.org/0000-0003-1582-6924; Huber, Robert; Lichtenthaler, Stefan F. ORCID: https://orcid.org/0000-0003-2211-2575; Schmuck, Carsten ORCID: https://orcid.org/0000-0001-6062-0357; Giese, Michael; Kaiser, Markus ORCID: https://orcid.org/0000-0002-6540-8520; Ehrmann, Michael ORCID: https://orcid.org/0000-0002-1927-260X und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2024):
Rational correction of pathogenic conformational defects in HTRA1.
In: Nature Communications, Bd. 15, 5944
[PDF, 3MB]
Malik, Rainer ORCID: https://orcid.org/0000-0001-9212-2520; Beaufort, Nathalie ORCID: https://orcid.org/0000-0002-7088-4206; Li, Jiang; Tanaka, Koki; Georgakis, Marios K. ORCID: https://orcid.org/0000-0003-3507-3659; He, Yunye ORCID: https://orcid.org/0000-0001-8581-7826; Koido, Masaru ORCID: https://orcid.org/0000-0002-0348-0666; Terao, Chikashi ORCID: https://orcid.org/0000-0002-6452-4095; Japan, BioBank; Anderson, Christopher D.; Kamatani, Yoichiro; Zand, Ramin und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2024):
Genetically proxied HTRA1 protease activity and circulating levels independently predict risk of ischemic stroke and coronary artery disease.
In: Nature Cardiovascular Research, Bd. 3, Nr. 6: S. 701-713
ORCID: https://orcid.org/0000-0001-9212-2520; Beaufort, Nathalie ORCID: https://orcid.org/0000-0002-7088-4206; Li, Jiang; Tanaka, Koki; Georgakis, Marios K. ORCID: https://orcid.org/0000-0003-3507-3659; He, Yunye ORCID: https://orcid.org/0000-0001-8581-7826; Koido, Masaru ORCID: https://orcid.org/0000-0002-0348-0666; Terao, Chikashi ORCID: https://orcid.org/0000-0002-6452-4095; Japan, BioBank; Anderson, Christopher D.; Kamatani, Yoichiro; Zand, Ramin und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2024):
Genetically proxied HTRA1 protease activity and circulating levels independently predict risk of ischemic stroke and coronary artery disease.
In: Nature Cardiovascular Research, Bd. 3, Nr. 6: S. 701-713
Zellner, Andreas; Müller, Stephan A.; Lindner, Barbara; Beaufort, Nathalie; Rozemuller, Annemieke J. M.; Arzberger, Thomas; Gassen, Nils C.; Lichtenthaler, Stefan F.; Kuster, Bernhard; Haffner, Christof und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2022):
Proteomic profiling in cerebral amyloid angiopathy reveals an overlap with CADASIL highlighting accumulation of HTRA1 and its substrates.
In: Acta neuropathologica communications, Bd. 10, 6
[PDF, 37MB]
ORCID: https://orcid.org/0000-0002-0654-387X
(2022):
Proteomic profiling in cerebral amyloid angiopathy reveals an overlap with CADASIL highlighting accumulation of HTRA1 and its substrates.
In: Acta neuropathologica communications, Bd. 10, 6
[PDF, 37MB]
Asare, Yaw ORCID: https://orcid.org/0000-0002-8946-5650; Shnipova, Margarita; Živković, Luka; Schlegl, Christina ORCID: https://orcid.org/0000-0001-7314-5954; Tosato, Federica ORCID: https://orcid.org/0000-0002-2783-4764; Aronova, Arailym ORCID: https://orcid.org/0000-0002-1337-2415; Brandhofer, Markus; Strohm, Laura; Beaufort, Nathalie; Malik, Rainer; Weber, Christian ORCID: https://orcid.org/0000-0003-4610-8714; Bernhagen, Jürgen ORCID: https://orcid.org/0000-0003-2996-2652 und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2022):
IKKβ binds NLRP3 providing a shortcut to inflammasome activation for rapid immune responses.
In: Signal Transduction and Targeted Therapy, Bd. 7, 355
[PDF, 1MB]
ORCID: https://orcid.org/0000-0002-8946-5650; Shnipova, Margarita; Živković, Luka; Schlegl, Christina ORCID: https://orcid.org/0000-0001-7314-5954; Tosato, Federica ORCID: https://orcid.org/0000-0002-2783-4764; Aronova, Arailym ORCID: https://orcid.org/0000-0002-1337-2415; Brandhofer, Markus; Strohm, Laura; Beaufort, Nathalie; Malik, Rainer; Weber, Christian ORCID: https://orcid.org/0000-0003-4610-8714; Bernhagen, Jürgen ORCID: https://orcid.org/0000-0003-2996-2652 und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2022):
IKKβ binds NLRP3 providing a shortcut to inflammasome activation for rapid immune responses.
In: Signal Transduction and Targeted Therapy, Bd. 7, 355
[PDF, 1MB]
Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Beaufort, Nathalie; Debette, Stephanie und Anderson, Christopher D.
(2021):
Stroke Genetics Turning Discoveries into Clinical Applications.
In: Stroke, Bd. 52, Nr. 9: S. 2974-2982
[PDF, 91kB]
ORCID: https://orcid.org/0000-0002-0654-387X; Beaufort, Nathalie; Debette, Stephanie und Anderson, Christopher D.
(2021):
Stroke Genetics Turning Discoveries into Clinical Applications.
In: Stroke, Bd. 52, Nr. 9: S. 2974-2982
[PDF, 91kB]
Malik, Rainer; Beaufort, Nathalie; Frerich, Simon; Gesierich, Benno; Georgakis, Marios K.; Rannikmae, Kristiina; Ferguson, Amy C.; Haffner, Christof; Traylor, Matthew; Ehrmann, Michael; Sudlow, Cathie L. M. und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2021):
Whole-exome sequencing reveals a role of HTRA1 and EGFL8 in brain white matter hyperintensities.
In: Brain, Bd. 144: S. 2670-2682
[PDF, 1MB]
ORCID: https://orcid.org/0000-0002-0654-387X
(2021):
Whole-exome sequencing reveals a role of HTRA1 and EGFL8 in brain white matter hyperintensities.
In: Brain, Bd. 144: S. 2670-2682
[PDF, 1MB]
Soelch, Susanne; Beaufort, Nathalie; Loessner, Daniela; Kotzsch, Matthias; Reuning, Ute; Luther, Thomas; Kirchner, Thomas und Magdolen, Viktor
(2021):
Rab31-dependent regulation of transforming growth factor ss expression in breast cancer cells.
In: Molecular Medicine, Bd. 27, Nr. 1, 158
Malik, Rainer; Dau, Therese; Gonik, Maria; Sivakumar, Anirudh; Deredge, Daniel J.; Edeleva, Evgeniia V.; Götzfried, Jessica; Laan, Sander W. van der; Pasterkamp, Gerard; Beaufort, Nathalie; Seixas, Susana; Bevan, Steve; Lincz, Lisa F.; Holliday, Elizabeth G.; Burgess, Annette I.; Rannikmae, Kristiina; Minnerup, Jens; Kriebel, Jennifer; Waldenberger, Melanie; Müller-Nurasyid, Martina; Lichtner, Peter; Saleheen, Danish; Rothwell, Peter M.; Levi, Christopher; Attia, John; Sudlow, Cathie L. M.; Braun, Dieter; Markus, Hugh S.; Wintrode, Patrick L.; Berger, Klaus; Jenne, Dieter E. und Dichgans, Martin
(2017):
Common coding variant in SERPINA1 increases the risk for large artery stroke.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 114, Nr. 14: S. 3613-3618
[PDF, 1MB]
Kast, Jessica; Hanecker, Patrizia; Beaufort, Nathalie; Giese, Armin; Joutel, Anne; Dichgans, Martin; Opherk, Christian und Haffner, Christof
(2014):
Sequestration of latent TGF-β binding protein 1 into CADASIL-related Notch3-ECD deposits.
In: Acta Neuropathologica Communications
2:96
[PDF, 2MB]
Beaufort, Nathalie; Plaza, Karolina; Utzschneider, Daniel; Schwarz, Amelie; Burkhart, Julia M.; Creutzburg, Sabine; Debela, Mekdes; Schmitt, Manfred; Ries, Christian und Magdolen, Viktor
(2010):
Interdependence of kallikrein-related peptidases in proteolytic networks.
In: Biological Chemistry, Bd. 391, Nr. 5: S. 581-587
[PDF, 252kB]