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Anzahl der Publikationen: 47
Zeitschriftenartikel
Pastore, Friederike 
ORCID: https://orcid.org/0000-0002-2220-2346; Pastore, Alessandro; Rothenberg-Thurley, Maja; Metzeler, Klaus H.; Ksienzyk, Bianka; Schneider, Stephanie; Bohlander, Stefan K.; Braess, Jan; Sauerland, Maria C.; Görlich, Dennis; Berdel, Wolfgang E.; Wörmann, Bernhard; Bergwelt-Baildon, Michael von; Hiddemann, Wolfgang und Spiekermann, Karsten
(2022):
Molecular profiling of patients with cytogenetically normal acute myeloid leukemia and hyperleukocytosis.
In: Cancer, Bd. 128, Nr. 24: S. 4213-4222
[PDF, 1MB]
ORCID: https://orcid.org/0000-0002-2220-2346; Pastore, Alessandro; Rothenberg-Thurley, Maja; Metzeler, Klaus H.; Ksienzyk, Bianka; Schneider, Stephanie; Bohlander, Stefan K.; Braess, Jan; Sauerland, Maria C.; Görlich, Dennis; Berdel, Wolfgang E.; Wörmann, Bernhard; Bergwelt-Baildon, Michael von; Hiddemann, Wolfgang und Spiekermann, Karsten
(2022):
Molecular profiling of patients with cytogenetically normal acute myeloid leukemia and hyperleukocytosis.
In: Cancer, Bd. 128, Nr. 24: S. 4213-4222
[PDF, 1MB]
Schaenzer, Anne; Achleitner, Melanie T.; Truembach, Dietrich; Hubert, Laurence; Munnich, Arnold; Ahlemeyer, Barbara; AlAbdulrahim, Maha M.; Greif, Philipp A.; Vosberg, Sebastian; Hummer, Blake; Feichtinger, Rene G.; Mayr, Johannes A.; Wortmann, Saskia B.; Aichner, Heidi; Rudnik-Schoeneborn, Sabine; Ruiz, Anna; Gabau, Elisabeth; Sanchez, Jacobo Perez; Ellard, Sian; Homfray, Tessa; Stals, Karen L.; Wurst, Wolfgang; Neubauer, Bernd A.; Acker, Till; Bohlander, Stefan K.; Asensio, Cedric; Besmond, Claude; Alkuraya, Fowzan S.; AlSayed, Moenaldeen D.; Hahn, Andreas und Weber, Axel
(2021):
Mutations in HID1 Cause Syndromic Infantile Encephalopathy and Hypopituitarism.
In: Annals of Neurology, Bd. 90, Nr. 1: S. 143-158
[PDF, 7MB]
Opatz, Sabrina; Bamopoulos, Stefanos A.; Metzeler, Klaus H.; Herold, Tobias; Ksienzyk, Bianka; Braeundl, Kathrin; Tschuri, Sebastian; Vosberg, Sebastian; Konstandin, Nikola P.; Wang, Christine; Hartmann, Luise; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Schneider, Stephanie; Thiede, Christian; Middeke, Jan Moritz; Stoelzel, Friedrich; Roellig, Christoph; Schetelig, Johannes; Ehninger, Gerhard; Kraemer, Alwin; Braess, Jan; Goerlich, Dennis; Sauerland, Maria Cristina; Berdel, Wolfgang E.; Woermann, Bernhard J.; Hiddemann, Wolfgang; Spiekermann, Karsten; Bohlander, Stefan K. und Greif, Philipp A.
(2020):
The clinical mutatome of core binding factor leukemia.
In: Leukemia, Bd. 34, Nr. 6: S. 1553-1562
Herold, Tobias ORCID: https://orcid.org/0000-0002-9615-9432; Rothenberg-Thurley, Maja; Grunwald, Victoria V.; Janke, Hanna; Goerlich, Dennis; Sauerland, Maria C.; Konstandin, Nikola P.; Dufour, Annika; Schneider, Stephanie; Neusser, Michaela; Ksienzyk, Bianka; Greif, Philipp A.; Subklewe, Marion; Faldum, Andreas; Bohlander, Stefan K.; Braess, Jan; Wörmann, Bernhard; Krug, Utz; Berdel, Wolfgang E.; Hiddemann, Wolfgang; Spiekermann, Karsten und Metzeler, Klaus H.
(2020):
Validation and refinement of the revised 2017 European LeukemiaNet genetic risk stratification of acute myeloid leukemia.
In: Leukemia, Bd. 34: S. 3161-3172
[PDF, 2MB]
ORCID: https://orcid.org/0000-0002-9615-9432; Rothenberg-Thurley, Maja; Grunwald, Victoria V.; Janke, Hanna; Goerlich, Dennis; Sauerland, Maria C.; Konstandin, Nikola P.; Dufour, Annika; Schneider, Stephanie; Neusser, Michaela; Ksienzyk, Bianka; Greif, Philipp A.; Subklewe, Marion; Faldum, Andreas; Bohlander, Stefan K.; Braess, Jan; Wörmann, Bernhard; Krug, Utz; Berdel, Wolfgang E.; Hiddemann, Wolfgang; Spiekermann, Karsten und Metzeler, Klaus H.
(2020):
Validation and refinement of the revised 2017 European LeukemiaNet genetic risk stratification of acute myeloid leukemia.
In: Leukemia, Bd. 34: S. 3161-3172
[PDF, 2MB]
Bamopoulos, Stefanos A.; Batcha, Aarif M. N.; Jurinovic, Vindi; Rothenberg-Thurley, Maja; Janke, Hanna; Ksienzyk, Bianka; Philippou-Massier, Julia; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Schneider, Stephanie; Konstandin, Nikola; Sauerland, Maria Cristina; Görlich, Dennis; Berdel, Wolfgang E.; Woermann, Bernhard J.; Bohlander, Stefan K.; Canzar, Stefan; Mansmann, Ulrich; Hiddemann, Wolfgang; Braess, Jan; Spiekermann, Karsten; Metzeler, Klaus H. und Herold, Tobias
(2020):
Clinical presentation and differential splicing of SRSF2, U2AF1 and SF3B1 mutations in patients with acute myeloid leukemia.
In: Leukemia, Bd. 34, Nr. 10: S. 2621-2634
Barbosa, Karina; Deshpande, Anagha; Chen, Bo-Rui; Ghosh, Anwesha; Sun, Younguk; Dutta, Sayantanee; Weetall, Marla; Dixon, Jesse; Armstrong, Scott A.; Bohlander, Stefan K. und Deshpande, Aniruddha J.
(2019):
Acute myeloid leukemia driven by the CALM-AF10 fusion gene is dependent on BMI1.
In: Experimental Hematology, Bd. 74: S. 42-51
Angenendt, Linus; Bormann, Eike; Pabst, Caroline; Alla, Vijay; Goerlich, Dennis; Braun, Leonie; Dohlich, Kim; Schwoeppe, Christian; Bohlander, Stefan K.; Arteaga, Maria Francisca; Wethmar, Klaus; Hartmann, Wolfgang; Angenendt, Adrian; Kessler, Torsten; Mesters, Rolf M.; Stelljes, Matthias; Rothenberg-Thurley, Maja; Spiekermann, Karsten; Hebert, Josee; Sauvageau, Guy; Valk, Peter J. M.; Loewenberg, Bob; Serve, Hubert; Müller-Tidow, Carsten; Lenz, Georg; Woermann, Bernhard J.; Sauerland, M. Christina; Hiddemann, Wolfgang; Berdel, Wolfgang E.; Krug, Utz; Metzeler, Klaus H.; Mikesch, Jan-Henrik; Herold, Tobias und Schliemann, Christoph
(2019):
The neuropeptide receptor calcitonin receptor-like (CALCRL) is a potential therapeutic target in acute myeloid leukemia.
In: Leukemia, Bd. 33, Nr. 12: S. 2830-2841
Batcha, Aarif M. N.; Bamopoulos, Stefanos A.; Kerbs, Paul; Kumar, Ashwini; Jurinovic, Vindi; Rothenberg-Thurley, Maja; Ksienzyk, Bianka; Philippou-Massier, Julia; Krebs, Stefan; Blum, Helmut; Schneider, Stephanie; Konstandin, Nikola; Bohlander, Stefan K.; Heckman, Caroline; Kontro, Mika; Hiddemann, Wolfgang; Spiekermann, Karsten; Braess, Jan; Metzeler, Klaus H.; Greif, Philipp A.; Mansmann, Ulrich und Herold, Tobias
(2019):
Allelic Imbalance of Recurrently Mutated Genes in Acute Myeloid Leukaemia.
In: Scientific Reports, Bd. 9, Nr. 11796
[PDF, 1MB]
Herold, Tobias; Jurinovic, Vindi; Batcha, Aarif Mohamed Nazeer; Bamopoulos, Stefanos A.; Rothenberg-Thurley, Maja; Ksienzyk, Bianka; Hartmann, Luise; Greif, Philipp A.; Phillippou-Massier, Julia; Krebs, Stefan; Blum, Helmut; Amler, Susanne; Schneider, Stephanie; Konstandin, Nikola P.; Sauerland, Maria Cristina; Görlich, Dennis; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Tischer, Johanna; Subklewe, Marion; Bohlander, Stefan K.; Braess, Jan; Hiddemann, Wolfgang; Metzeler, Klaus H.; Mansmann, Ulrich und Spiekermann, Karsten
(März 2018):
A 29-gene and cytogenetic score for the prediction of resistance to induction treatment in acute myeloid leukemia.
In: Haematologica, Bd. 103, Nr. 3: S. 456-65
Rothenberg-Thurley, Maja; Amler, Susanne; Goerlich, Dennis; Köhnke, Thomas; Konstandin, Nikola P.; Schneider, Stephanie; Sauerland, Maria C.; Herold, Tobias; Hubmann, Max; Ksienzyk, Bianka; Zellmeier, Evelyn; Bohlander, Stefan K.; Subklewe, Marion; Faldum, Andreas; Hiddemann, Wolfgang; Braess, Jan; Spiekermann, Karsten und Metzeler, Klaus H.
(2018):
Persistence of pre-leukemic clones during first remission and risk of relapse in acute myeloid leukemia.
In: Leukemia, Bd. 32, Nr. 7: S. 1598-1608
Prassek, Victoria V.; Rothenberg-Thurley, Maja; Sauerland, Maria C.; Herold, Tobias; Janke, Hanna; Ksienzyk, Bianka; Konstandin, Nikola P.; Goerlich, Dennis; Krug, Utz; Faldum, Andreas; Berdel, Wolfgang E.; Wörmann, Bernhard; Braess, Jan; Schneider, Stephanie; Subklewe, Marion; Bohlander, Stefan K.; Hiddemann, Wolfgang; Spiekermann, Karsten und Metzeler, Klaus H.
(2018):
Genetics of acute myeloid leukemia in the elderly: mutation spectrum and clinical impact in intensively treated patients aged 75 years or older.
In: Haematologica, Bd. 103, Nr. 11: S. 1853-1861
[PDF, 1MB]
Bräss, Jan; Amler, Susanne; Kreuzer, Karl-Anton; Spiekermann, Karsten; Lindemann, Hans Walter; Lengfelder, Eva; Graeven, Ullrich; Staib, Peter; Ludwig, Wolf-Dieter; Biersack, Harald; Ko, Yon-Dschun; Uppenkamp, Michael J.; Wit, Maike de; Korsten, Stefan; Peceny, Rudolf; Gaska, Tobias; Schiel, Xaver; Behringer, Dirk M.; Kiehl, Michael G.; Zinngrebe, Bettina; Meckenstock, Gerald; Römer, Eva; Medgenberg, Dirk; Spaeth-Schwalbe, Ernst; Massenkeil, Gero; Hindahl, Heidrun; Schwerdtfeger, Rainer; Trenn, Guido; Sauerland, Cristina; Koch, Raphael; Lablans, Martin; Faldum, Andreas; Görlich, Dennis; Bohlander, Stefan K.; Schneider, Stephanie; Dufour, Annika; Buske, Christian; Fiegl, Michael; Subklewe, Marion; Bräss, Birgit; Unterhalt, Michael; Baumgartner, Anja; Wörmann, Bernhard; Beelen, Dietrich und Hiddemann, Wolfgang
(2018):
Sequential high-dose cytarabine and mitoxantrone (S-HAM) versus standard double induction in acute myeloid leukemia-a phase 3 study.
In: Leukemia, Bd. 32, Nr. 12: S. 2558-2571
Konstandin, Nikola P.; Pastore, Friederike; Herold, Tobias; Dufour, Annika; Rothenberg-Thurley, Maja; Hinrichsen, Tanja; Ksienzyk, Bianka; Tschuri, Sebastian; Schneider, Stephanie; Hoster, Eva; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Sauerland, Maria C.; Braess, Jan; Bohlander, Stefan K.; Klein, Hanns-Georg; Hiddemann, Wolfgang; Metzeler, Klaus H. und Spiekermann, Karsten
(2018):
Genetic heterogeneity of cytogenetically normal AML with mutations of CEBPA.
In: Blood Advances, Bd. 2, Nr. 20: S. 2724-2731
Schranz, Katrin; Hubmann, Max; Harin, Egor; Vosberg, Sebastian; Herold, Tobias; Metzeler, Klaus H.; Rothenberg-Thurley, Maja; Janke, Hanna; Bräundl, Kathrin; Ksienzyk, Bianka; Batcha, Aarif M. N.; Schaaf, Sebastian; Schneider, Stephanie; Bohlander, Stefan K.; Görlich, Dennis; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Braess, Jan; Krebs, Stefan; Hiddemann, Wolfgang; Mansmann, Ulrich; Spiekermann, Karsten und Greif, Philipp A.
(2018):
Clonal heterogeneity of FLT3-ITD detected by high-throughput amplicon sequencing correlates with adverse prognosis in acute myeloid leukemia.
In: Oncotarget, Bd. 9, Nr. 53: S. 30128-30145
[PDF, 2MB]
Hornung, Roman; Jurinovic, Vindi; Batcha, Aarif M. N.; Bamopoulos, Stefanos A.; Rothenberg-Thurley, Maja; Amler, Susanne; Sauerland, Maria Cristina; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Bohlander, Stefan K.; Braess, Jan; Hiddemann, Wolfgang; Lehmann, Sören; Mareschal, Sylvain; Spiekermann, Karsten; Metzeler, Klaus H.; Herold, Tobias und Boulesteix, Anne-Laure
(2018):
Mediation analysis reveals common mechanisms of RUNX1 point mutations and RUNX1/RUNX1T1 fusions influencing survival of patients with acute myeloid leukemia.
In: Scientific Reports, Bd. 8, Nr. 1: S. 1-13
[PDF, 1MB]
Greif, Philipp A.; Hartmann, Luise; Vosberg, Sebastian; Stief, Sophie M.; Mattes, Raphael; Hellmann, Ines; Metzeler, Klaus H.; Herold, Tobias; Bamopoulos, Stefanos A.; Kerbs, Paul; Jurinovic, Vindi; Schumacher, Daniela; Pastore, Friederike; Bräundl, Kathrin; Zellmeier, Evelyn; Ksienzyk, Bianka; Konstandin, Nikola P.; Schneider, Stephanie; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Neumann, Martin; Baldus, Claudia D.; Bohlander, Stefan K.; Wolf, Stephan; Görlich, Dennis; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Hiddemann, Wolfgang und Spiekermann, Karsten
(2018):
Evolution of Cytogenetically Normal Acute Myeloid Leukemia During Therapy and Relapse: An Exome Sequencing Study of 50 Patients.
In: Clinical Cancer Research, Bd. 24, Nr. 7: S. 1716-1726
Herold, Tobias; Schneider, S.; Metzeler, Klaus H.; Neumann, Martin; Hartmann, Luise; Roberts, Kathryn G.; Konstandin, Nikola P.; Greif, Philipp A.; Bräundl, Kathrin; Ksienzyk, Bianka; Huk, Natalia; Schneider, Irene; Zellmeier, Evelyn; Jurinovic, Vindi; Mansmann, Ulrich; Hiddemann, Wolfgang; Mullighan, Charles G.; Bohlander, Stefan K.; Spiekermann, Karsten; Hölzel, Dieter; Brüggemann, Monika; Baldus, Claudia D.; Dreyling, Martin und Gökbuget, Nicola
(2017):
Adults with Philadelphia chromosome–like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis.
In: Haematologica, Bd. 102, Nr. 1: S. 130-138
[PDF, 1MB]
Bogen, Anja; Buske, Christian; Hiddemann, Wolfgang; Bohlander, Stefan K. und Christ, Oliver
(2017):
Variable aldehyde dehydrogenase activity and effects on chemosensitivity of primitive human leukemic cells.
In: Experimental Hematology, Bd. 47: S. 54-63
Herold, Tobias; Metzeler, Klaus H.; Vosberg, Sebastian; Hartmann, Luise; Jurinovic, Vindi; Opatz, Sabrina; Konstandin, Nikola P.; Schneider, S.; Zellmeier, Evelyn; Ksienzyk, Bianka; Graf, A.; Krebs, S.; Blum, H.; Sauerland, Maria Cristina; Büchner, T.; Berdel, W. E.; Wörmann, Bernhard; Mansmann, Ulrich; Hiddemann, Wolfgang; Bohlander, Stefan K.; Spiekermann, Karsten und Greif, Philipp A.
(2017):
Acute Myeloid Leukemia with Del(9q) is Characterized by Frequent Mutations of NPM1, DNMT3A, WT1 and Low Expression of TLE4.
In: Genes, Chromosomes and Cancer, Bd. 56, Nr. 1: S. 75-86
Sandhöfer, Nadine; Metzeler, Klaus H.; Kakadia, Purvi M.; Pasalic, Zlatana; Hiddemann, Wolfgang; Neusser, Michaela; Steinlein, Ortrud; Fiegl, Michael; Subklewe, Marion; Spiekermann, Karsten; Bohlander, Stefan K.; Schneider, Stephanie und Bräss, Jan
(2017):
A fluorescence in situ hybridization-based screen allows rapid detection of adverse cytogenetic alterations in patients with acute myeloid leukemia.
In: Genes Chromosomes & Cancer, Bd. 56, Nr. 8: S. 632-638
Niavarani, Ahmadreza; Herold, Tobias; Reyal, Yasmin; Sauerland, Maria C.; Buchner, Thomas; Hiddemann, Wolfgang; Bohlander, Stefan K.; Valk, Peter J. M. und Bonnet, Dominique
(2016):
A 4-gene expression score associated with high levels of Wilms Tumor-1 (WT1) expression is an adverse prognostic factor in acute myeloid leukaemia.
In: British Journal of Haematology, Bd. 172, Nr. 3: S. 401-411
Laverdière, Isabelle; Boileau, Meaghan; Herold, Tobias; Rak, Janusz; Berdel, Wolfgang E.; Wörmann, Bernhard; Hiddemann, Wolfgang; Spiekermann, Karsten; Bohlander, Stefan K. und Eppert, Kolja
(2016):
Complement cascade gene expression defines novel prognostic subgroups of acute myeloid leukemia.
In: Experimental Hematology, Bd. 44, Nr. 11: S. 1039-1043
Metzeler, Klaus H.; Herold, Tobias; Rothenberg-Thurley, Maja; Amler, Susanne; Sauerland, Maria C.; Görlich, Dennis; Schneider, Stephanie; Konstandin, Nikola P.; Dufour, Annika; Bräundl, Kathrin; Ksienzyk, Bianka; Zellmeier, Evelyn; Hartmann, Luise; Greif, Philipp A.; Fiegl, Michael; Subklewe, Marion; Bohlander, Stefan K.; Krug, Utz; Faldum, Andreas; Berdel, Wolfgang E.; Wörmann, Bernhard; Büchner, Thomas; Hiddemann, Wolfgang; Braess, Jan und Spiekermann, Karsten
(2016):
Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia.
In: Blood, Bd. 128, Nr. 5: S. 686-698
Pabst, Caroline; Bergeron, Anne; Lavallée, Vincent-Philippe; Yeh, Jonathan; Gendron, Patrick; Norddahl, Gudmundur L.; Krosl, Jana; Boivin, Isabel; Deneault, Eric; Simard, Jessica; Imren, Suzan; Boucher, Geneviève; Eppert, Kolja; Herold, Tobias; Bohlander, Stefan K.; Humphries, Keith; Lemieux, Sebastien; Hebert, Josée; Sauvageau, Guy und Barabé, Frédéric
(2016):
GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo.
In: Blood, Bd. 127, Nr. 16: S. 2018-2027
Jiang, Xi; Hu, Chao; Arnovitz, Stephen; Bugno, Jason; Yu, Miao; Zuo, Zhixiang; Chen, Ping; Huang, Hao; Ulrich, Bryan; Gurbuxani, Sandeep; Weng, Hengyou; Strong, Jennifer; Wang, Yungui; Li, Yuanyuan; Salat, Justin; Li, Shenglai; Elkahloun, Abdel G.; Yang, Yang; Neilly, Mary Beth; Larson, Richard A.; Le Beau, Michelle M.; Herold, Tobias; Bohlander, Stefan K.; Liu, Paul P.; Zhang, Jiwang; Li, Zejuan; He, Chuan; Jin, Jie; Hong, Seungpyo und Chen, Jianjun
(2016):
miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia.
In: Nature Communications, Bd. 7, 11452
[PDF, 3MB]
Hartmann, Luise; Dutta, Sayantanee; Opatz, Sabrina; Vosberg, Sebastian; Reiter, Katrin; Leubolt, Georg; Metzeler, Klaus H.; Herold, Tobias; Bamopoulos, Stefanos A.; Bräundl, Kathrin; Zellmeier, Evelyn; Ksienzyk, Bianka; Konstandin, Nikola P.; Schneider, Stephanie; Hopfner, Karl-Peter; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Middeke, Jan Moritz; Stölzel, Friedrich; Thiede, Christian; Wolf, Stephan; Bohlander, Stefan K.; Preiss, Caroline; Chen-Wichmann, Linping; Wichmann, Christian; Sauerland, Maria Cristina; Büchner, Thomas; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Braess, Jan; Hiddemann, Wolfgang; Spiekermann, Karsten und Greif, Philipp A.
(2016):
ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation.
In: Nature Communications, Bd. 7, 11733
[PDF, 1MB]
Vosberg, Sebastian; Herold, Tobias; Hartmann, Luise; Neumann, Martin; Opatz, Sabrina; Metzeler, Klaus H.; Schneider, S.; Graf, A.; Krebs, S.; Blum, H.; Baldus, Claudia D.; Hiddemann, Wolfgang; Spiekermann, Karsten; Bohlander, Stefan K.; Mansmann, Ulrich und Greif, Philipp A.
(2016):
Close Correlation of Copy Number Aberrations Detected by Close correlation of copy number aberrations detected by next-generation sequencing with results from routine cytogenetics in acute myeloid leukemia.
In: Genes, Chromosomes and Cancer, Bd. 55, Nr. 7: S. 553-567
Jiang, Xi; Bugno, Jason; Hu, Chao; Yang, Yang; Herold, Tobias; Qi, Jun; Chen, Ping; Gurbuxani, Sandeep; Arnovitz, Stephen; Strong, Jennifer; Ferchen, Kyle; Ulrich, Bryan; Weng, Hengyou; Wang, Yungui; Huang, Hao; Li, Shenglai; Neilly, Mary Beth; Larson, Richard A.; Le Beau, Michelle M.; Bohlander, Stefan K.; Jin, Jie; Li, Zejuan; Bradner, James E.; Hong, Seungpyo und Chen, Jianjun
(2016):
Eradication of Acute Myeloid Leukemia with FLT3 Ligand-Targeted miR-150 Nanoparticles.
In: Cancer Research, Bd. 76, Nr. 15: S. 4470-4480
Janke, Hanna; Pastore, Friederike; Schumacher, Daniela; Herold, Tobias; Hopfner, Karl-Peter; Schneider, Stephanie; Berdel, Wolfgang E.; Büchner, Thomas; Woermann, Bernhard J.; Subklewe, Marion; Bohlander, Stefan K.; Hiddemann, Wolfgang; Spiekermann, Karsten und Polzer, Harald
(2014):
Activating FLT3 Mutants Show Distinct Gain-of-Function Phenotypes In Vitro and a Characteristic Signaling Pathway Profile Associated with Prognosis in Acute Myeloid Leukemia.
In: PLOS ONE 9(3), e89560 [PDF, 2MB]
In: PLOS ONE 9(3), e89560 [PDF, 2MB]
Hubmann, Max; Köhnke, Thomas; Hoster, Eva; Schneider, Stephanie; Dufour, Annika; Zellmeier, Evelyn; Fiegl, Michael; Braess, Jan; Bohlander, Stefan K.; Subklewe, Marion; Sauerland, Maria-Cristina; Berdel, Wolfgang E.; Büchner, Thomas; Woermann, Bernhard; Hiddemann, Wolfgang und Spiekermann, Karsten
(2014):
Molecular response assessment by quantitative real-time polymerase chain reaction after induction therapy in NPM1-mutated patients identifies those at high risk of relapse.
In: Haematologica, Bd. 99, Nr. 8: S. 1317-1325
[PDF, 838kB]
Krause, Luciana M. Fontanari; Japp, Anna Sophia; Krause, Alexandre; Mooster, Jana; Chopra, Martin; Müschen, Markus und Bohlander, Stefan K.
(2014):
Identification and characterization of OSTL (RNF217) encoding a RING-IBR-RING protein adjacent to a translocation breakpoint involving ETV6 in childhood ALL.
In: Scientific Reports, Bd. 4, 6565
[PDF, 1MB]
Li, Z.; Herold, Tobias; He, C.; Valk, P. J.; Chen, P.; Jurinovic, Vindi; Mansmann, Ulrich; Radmacher, M. D.; Maharry, K. S.; Sun, M.; Yang, X.; Huang, H.; Jiang, X.; Sauerland, M. C.; Büchner, T.; Hiddemann, Wolfgang; Elkahloun, A.; Neilly, M. B.; Zhang, Y.; Larson, R. A.; Le Beau, M. M.; Caligiuri, M. A.; Dohner, K.; Bullinger, L.; Liu, P. P.; Delwel, R.; Marcucci, G.; Lowenberg, B.; Bloomfield, C. D.; Rowley, J. D.; Bohlander, Stefan K. und Chen, J.
(2013):
Identification of a 24-Gene Prognostic Signature That Improves the European LeukemiaNet Risk Classification of Acute Myeloid Leukemia: An International Collaborative Study.
In: Journal of Clinical Oncology, Bd. 31, Nr. 9: S. 1172-1181
Herold, Tobias; Mulaw, M. A.; Jurinovic, Vindi; Seiler, T.; Metzeler, Klaus H.; Dufour, A.; Schneider, S.; Kakadia, P. M.; Spiekermann, Karsten; Mansmann, Ulrich; Hiddemann, Wolfgang; Buske, C.; Dreyling, Martin und Bohlander, Stefan K.
(2012):
High expression of MZB1 predicts adverse prognosis in chronic lymphocytic leukemia, follicular lymphoma and diffuse large B-cell lymphoma and is associated with a unique gene expression signature.
In: Leukemia & Lymphoma, Bd. 54, Nr. 8: S. 1652-1657
Greif, Philipp A.; Dufour, A.; Konstandin, Nikola P.; Ksienzyk, Bianka; Zellmeier, Evelyn; Tizazu, B.; Sturm, J.; Benthaus, T.; Herold, Tobias; Yaghmaie, M.; Dorge, P.; Hopfner, K. P.; Hauser, A.; Graf, A.; Krebs, S.; Blum, H.; Kakadia, P. M.; Schneider, S.; Hoster, Eva; Schneider, F.; Stanulla, M.; Braess, J.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Hiddemann, Wolfgang; Spiekermann, Karsten und Bohlander, Stefan K.
(2012):
GATA2 zinc finger 1 mutations associated with biallelic CEBPA mutations define a unique genetic entity of acute myeloid leukemia.
In: Blood, Bd. 120, Nr. 2: S. 395-403
Dufour, A.; Schneider, F.; Hoster, Eva; Benthaus, T.; Ksienzyk, Bianka; Schneider, S.; Kakadia, P. M.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Braess, J.; Subklewe, M.; Hiddemann, Wolfgang; Bohlander, Stefan K. und Spiekermann, Karsten
(2012):
Monoallelic CEBPA mutations in normal karyotype acute myeloid leukemia: independent favorable prognostic factor within NPM1 mutated patients.
In: Annals of Hematology, Bd. 91, Nr. 7: S. 1051-1063
Schneider, F.; Hoster, Eva; Unterhalt, Michael; Schneider, S.; Dufour, A.; Benthaus, T.; Mellert, G.; Zellmeier, Evelyn; Kakadia, P. M.; Bohlander, Stefan K.; Feuring-Buske, M.; Buske, C.; Braess, J.; Heinecke, A.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Hiddemann, Wolfgang und Spiekermann, Karsten
(2012):
The FLT3ITD level has a high prognostic impact in NPM1 mutated, but not NPM1 unmutated AML with a normal karyotype.
In: Blood, Bd. 119, Nr. 19: S. 4383-4386
Schneider, F.; Hoster, Eva; Schneider, S.; Dufour, A.; Benthaus, T.; Kakadia, P. M.; Bohlander, Stefan K.; Braess, J.; Heinecke, A.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Feuring-Buske, M.; Buske, C.; Creutzig, U.; Thiede, C.; Zwaan, M. C.; Heuvel-Eibrink, M. M. van den; Reinhardt, D.; Hiddemann, Wolfgang und Spiekermann, Karsten
(2012):
Age-dependent frequencies of NPM1 mutations and FLT3-ITD in patients with normal karyotype AML (NK-AML).
In: Annals of Hematology, Bd. 91, Nr. 1: S. 9-18
Herold, Tobias; Jurinovic, Vindi; Mulaw, M.; Seiler, T.; Dufour, A.; Schneider, S.; Kakadia, P. M.; Feuring-Buske, M.; Braess, J.; Spiekermann, Karsten; Mansmann, Ulrich; Hiddemann, Wolfgang; Buske, C. und Bohlander, Stefan K.
(2011):
Expression analysis of genes located in the minimally deleted regions of 13q14 and 11q22-23 in chronic lymphocytic leukemia-unexpected expression pattern of the RHO GTPase activator ARHGAP20.
In: Genes, Chromosomes and Cancer, Bd. 50, Nr. 7: S. 546-558
Herold, Tobias; Jurinovic, Vindi; Metzeler, Klaus H.; Boulesteix, Anne-Laure; Bergmann, M.; Seiler, T.; Mulaw, M.; Thoene, S.; Dufour, A.; Pasalic, Z.; Schmidberger, Markus; Schmidt, M.; Schneider, S.; Kakadia, P. M.; Feuring-Buske, M.; Braess, J.; Spiekermann, Karsten; Mansmann, Ulrich; Hiddemann, Wolfgang; Buske, C. und Bohlander, Stefan K.
(2011):
An eight-gene expression signature for the prediction of survival and time to treatment in chronic lymphocytic leukemia.
In: Leukemia, Bd. 25, Nr. 10: S. 1639-1645
Dufour, A.; Schneider, F.; Metzeler, Klaus H.; Hoster, Eva; Schneider, S.; Zellmeier, Evelyn; Benthaus, T.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Braess, J.; Hiddemann, Wolfgang; Bohlander, Stefan K. und Spiekermann, Karsten
(2010):
Acute myeloid leukemia with biallelic CEBPA gene mutations and normal karyotype represents a distinct genetic entity associated with a favorable clinical outcome.
In: Journal of Clinical Oncology, Bd. 28, Nr. 4: S. 570-577
Schneider, F.; Hoster, Eva; Unterhalt, Michael; Schneider, S.; Dufour, A.; Benthaus, T.; Mellert, G.; Zellmeier, Evelyn; Bohlander, Stefan K.; Feuring-Buske, M.; Buske, C.; Braess, J.; Fritsch, S.; Heinecke, A.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Hiddemann, Wolfgang und Spiekermann, Karsten
(2009):
NPM1, but not FLT3-ITD mutations predict early blast cell clearance and CR rate in patients with normal karyotype AML (NK-AML) or high risk myelodysplastic syndrome (MDS).
In: Blood, Bd. 113, Nr. 21: S. 5250-5253
Reiff, T.; Stingele, R.; Eckstein, H. H.; Fraedrich, G.; Jansen, O.; Mudra, H.; Mansmann, Ulrich; Hacke, W.; Ringleb, P. A.; Metzeler, Klaus H.; Dufour, A.; Benthaus, T.; Hummel, Martina; Sauerland, M. C.; Heinecke, A.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Braess, J.; Spiekermann, Karsten; Hiddemann, Wolfgang; Buske, C.; Bohlander, Stefan K.; Nagel, J. M.; Wegscheider, K.; Rohmel, J.; Fleckenstein, M.; Adrion, Christine ORCID: https://orcid.org/0000-0003-2408-2533; Schmitz-Valckenberg, S.; Gobel, A. P.; Bindewald-Wittich, A.; Scholl, H. und Holz, F.
(2009):
Stent-Protected Angioplasty in Asymptomatic Carotid Artery Stenosis vs. Endarterectomy: SPACE2 – a Three-Arm Randomised-Controlled Clinical Trial.
In: International Journal of Stroke, Bd. 4, Nr. 4: S. 294-299
ORCID: https://orcid.org/0000-0003-2408-2533; Schmitz-Valckenberg, S.; Gobel, A. P.; Bindewald-Wittich, A.; Scholl, H. und Holz, F.
(2009):
Stent-Protected Angioplasty in Asymptomatic Carotid Artery Stenosis vs. Endarterectomy: SPACE2 – a Three-Arm Randomised-Controlled Clinical Trial.
In: International Journal of Stroke, Bd. 4, Nr. 4: S. 294-299
Thoene, S.; Rawat, V. P.; Heilmeier, B.; Hoster, Eva; Metzeler, Klaus H.; Herold, Tobias; Hiddemann, Wolfgang; Gökbuget, Nicola; Hoelzer, D.; Bohlander, Stefan K.; Feuring-Buske, M. und Buske, C.
(2009):
The homeobox gene CDX2 is aberrantly expressed and associated with an inferior prognosis in patients with acute lymphoblastic leukemia.
In: Leukemia, Bd. 23, Nr. 4: S. 649-655
Metzeler, Klaus H.; Dufour, A.; Benthaus, T.; Hummel, Martina; Sauerland, M. C.; Heinecke, A.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Mansmann, Ulrich; Braess, J.; Spiekermann, Karsten; Hiddemann, Wolfgang; Buske, C. und Bohlander, Stefan K.
(2009):
ERG Expression Is an Independent Prognostic Factor and Allows Refined Risk Stratification in Cytogenetically Normal Acute Myeloid Leukemia: A Comprehensive Analysis of ERG, MN1, and BAALC Transcript Levels Using Oligonucleotide Microarrays.
In: Journal of Clinical Oncology, Bd. 27, Nr. 30: S. 5031-5038
Metzeler, Klaus H.; Dufour, Annika; Benthaus, Tobias; Hummel, Manuela; Sauerland, Maria-Cristina; Heinecke, Achim; Berdel, Wolfgang E.; Büchner, Thomas; Woermann, Bernhard; Mansmann, Ulrich; Braess, Jan; Spiekermann, Karsten; Hiddemann, Wolfgang; Buske, Christian und Bohlander, Stefan K.
(2009):
ERG expression is an independent prognostic factor and allows refined risk stratification in cytogenetically normal acute myeloid leukemia: A comprehensive analysis of ERG, MN1, and BAALC transcript levels using oligonucleotide microarrays.
In: Journal of Clinical Oncology, Bd. 27, Nr. 30: S. 5031-5038
Hummel, Manuela; Metzeler, Klaus H.; Buske, C.; Bohlander, Stefan K. und Mansmann, Ulrich
(2008):
Association between a Prognostic Gene Signature and Functional Gene Sets.
In: Bioinformatics and Biology Insights, Bd. 2: S. 329-341
Metzeler, Klaus H.; Hummel, Martina; Bloomfield, C. D.; Spiekermann, Karsten; Braess, J.; Sauerland, M. C.; Heinecke, A.; Radmacher, M. D.; Marcucci, G.; Whitman, SP.; Maharry, K.; Paschka, P.; Larson, RA.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Mansmann, Ulrich; Hiddemann, Wolfgang; Bohlander, Stefan K. und Buske, C.
(2008):
An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia.
In: Blood, Bd. 112, Nr. 10: S. 4193-4201