Anzahl der Publikationen: 23
2017
Rothenberg-Thurley, M.; Amler, S.; Goerlich, D.; Sauerland, M. C.; Schneider, S.; Konstandin, N. P.; Batcha, A. M.; Ksienzyk, B.; Zellmeier, E.; Mansmann, Ulrich; Subklewe, Marion; Bohlander, S. K.; Faldum, A.; Hiddemann, W.; Spiekermann, K.; Braess, J. und Metzeler, Klaus H.
(2017):
Persistence of Driver Mutations during Complete Remission Associates with Shorter Survival and Contributes to the Inferior Outcomes of Elderly Patients with Acute Myeloid Leukemia.
In: Annals of Hematology, Bd. 96:
S31-S32
Reiter, K.; Hubmann, M.; Harin, E.; Vosberg, S.; Braeundl, K.; Ksienzyk, B.; Schneider, S.; Dufour, A.; Zellmeier, E.; Bohlander, S. K.; Sauerland, C.; Berdel, W. E.; Woermann, B.; Buechner, T.; Braess, J.; Hiddemann, W.; Spiekermann, K. und Greif, A.
(2017):
Comparison of FLT3-ITD Detection of High-Throughput Amplicon Sequencing to Routine Diagnostics - A Retrospective Analysis of AMLCG Study Patients.
In: Annals of Hematology, Bd. 96:
S62-S62
Prassek, V. V.; Rothenberg-Thurley, M.; Herold, T.; Amler, S.; Sauerland, M. C.; Goerlich, D.; Janke, H.; Schneider, S.; Subklewe, Marion; Krug, U.; Faldum, A.; Berdel, W. E.; Woermann, B.; Buechner, T.; Braess, J.; Hiddemann, W.; Spiekermann, K. und Metzeler, K. H.
(2017):
AML Patients Aged >= 75 Years Enrolled into AMLCG Trials: Do Gene Mutations Impact Clinical Outcome in Very Old, Intensively Treated Patients?
In: Annals of Hematology, Bd. 96:
S63-S63
Bamopoulos, S. A.; Batcha, A. M. N.; Jurinovic, V.; Metzeler, K. H.; Thurley, M. Rothenberg; Ksienzyk, B.; Hartmann, L.; Greif, P. A.; Phillippou-Massier, J.; Krebs, S.; Blum, H.; Amler, S.; Schneider, S.; Konstandin, N.; Sauerland, M. C.; Berdel, W. E.; Woermann, B. J.; Bohlander, S. K.; Braess, J.; Hiddemann, W.; Mansmann, Ulrich; Spiekermann, K. und Herold, T.
(2017):
Characterization of Spliceosome Mutations in Patients with Acute Myeloid Leukemia.
In: Annals of Hematology, Bd. 96:
S60-S60
Prassek, V.; Rothenberg-Thurley, M.; Sauerland, M. C.; Amler, S.; Görlich, D.; Herold, T.; Janke, H.; Schneider, S.; Subklewe, M.; Krug, U.; Faldum, A.; Berdel, W. E.; Wörmann, B.; Braess, J.; Hiddemann, W.; Spiekermann, K. und Metzeler, K. H.
(2017):
AML patients aged >= 75 years enrolled into AMLCG trials: do genetic alterations impact clinical outcome in very old, intensively treated patients?
In: Haematologica, Bd. 102: S. 209-210
Herold, Tobias; Jurinovic, V.; Metzeler, K. H.; Batcha, A. M. N.; Bamopoulos, S. A.; Rothenberg-Thurley, M.; Ksienzyk, B.; Hartmann, L.; Greif, P. A.; Phillippou-Massier, J.; Krebs, S.; Blum, H.; Amler, S.; Schneider, S.; Konstandin, N.; Sauerland, M. C.; Berdel, W. E.; Wörmann, B. J.; Subklewe, M.; Fiegl, M.; Bohlander, S. K.; Braess, J.; Hiddemann, W.; Mansmann, Ulrich und Spiekermann, K.
(2017):
Prediction of Primary Refractory Acute Myeloid Leukemia.
In: Annals of Hematology, Bd. 96:
S25-S25
2016
Krug, U.; Berdel, W. E.; Gale, R. P.; Haferlach, C.; Schnittger, S.; Müller-Tidow, C.; Braess, J.; Spiekermann, K.; Staib, P.; Beelen, D.; Serve, H.; Schliemann, C.; Stelljes, M.; Balleisen, L.; Maschmeyer, G.; Grüneisen, A.; Eimermacher, H.; Giagounidis, A.; Rasche, H.; Hehlmann, R.; Lengfelder, E.; Thiel, E.; Reichle, A.; Aul, C.; Ludwig, W.-D.; Kern, W.; Haferlach, T.; Köpcke, W.; Görlich, D.; Sauerland, M. C.; Heinecke, A.; Wörmann, B. J.; Hiddemann, W. und Büchner, T.
(2016):
Increasing intensity of therapies assigned at diagnosis does not improve survival of adults with acute myeloid leukemia.
In: Leukemia, Bd. 30, Nr. 6: S. 1230-1236
Rothenberg-Thurley, M.; Amler, S.; Görlich, D.; Sauerland, M. C.; Schneider, S.; Konstandin, N. P.; Schaaf, S.; Nazeer Batcha, A. M.; Bräundl, K.; Ksienzyk, B.; Zellmaier, E.; Mansmann, Ulrich; Fiegl, M.; Subklewe, M.; Bohlander, S. K.; Faldum, A.; Hiddemann, W.; Spiekermann, K.; Braess, J. und Metzeler, K. H.
(2016):
Persistence of driver mutations during complete remission associates with shorter survival and contributes to the inferior outcomes of elderly patients with acute myeloid leukemia.
In: Oncology Research and Treatment, Bd. 39: S. 110-111
Pohlen, M.; Braess, J.; Thudium, J.; Schmid, C.; Kochanek, M.; Kreuzer, K.-A.; Görlich, D.; Gerth, U.; Rhode, C.; Müller-Tidow, C.; Stelljes, M.; Büchner, T.; Schlimok, G.; Hallek, M.; Waltenberger, J.; Hiddemann, W.; Berdel, W. E.; Heilmeier, B. und Krug, U.
(2016):
Patients with acute myeloid leukemia admitted to intensive care units: Scores predicting outcome and post-ICU survival.
In: Oncology Research and Treatment, Bd. 39: S. 51
Rothenberg-Thurley, M.; Amler, S.; Goerlich, D.; Sauerland, M. C.; Schneider, S.; Konstandin, N. P.; Schaaf, S.; Batcha, A. M. Nazeer; Bräundl, K.; Ksienzyk, B.; Zellmeier, E.; Mansmann, Ulrich; Fiegl, M.; Subklewe, M.; Bohlander, S. K.; Faldum, A.; Hiddemann, W.; Spiekermann, K.; Braess, J. und Metzeler, K. H.
(2016):
Persistence of driver mutations during complete remission associates with shorter survival and contributes to the inferior outcomes of elderly patients with acute myeloid leukemia.
In: Haematologica, Bd. 101: S. 23
Hartmann, L.; Dutta, S.; Opatz, S.; Vosberg, S.; Reiter, K.; Leubolt, G.; Metzeler, K. H.; Herold, T.; Bamopoulos, S. A.; Bräundl, K.; Zellmeier, E.; Ksienzyk, B.; Konstandin, N. P.; Schneider, S.; Hopfner, K. P.; Graf, A.; Krebs, S.; Blum, H.; Middeke, J. M.; Stölzel, F.; Thiede, C.; Wolf, S.; Bohlander, S. K.; Preiss, C.; Chen-Wichmann, L.; Wichmann, C.; Sauerland, M. C.; Büchner, T.; Berdel, W. E.; Wörmann, B. J.; Braess, J.; Hiddemann, W.; Spiekermann, K. und Greif, P. A.
(2016):
Frequent recurring mutations disrupt the anti-proliferative function of ZBTB7A in acute myeloid leukemia with t(8;21) translocation.
In: Haematologica, Bd. 101: S. 11
Büchner, T.; Krug, U. O.; Gale, R. Peter; Heinecke, A.; Sauerland, M. C.; Haferlach, C.; Schnittger, S.; Haferlach, T.; Müller-Tidow, C.; Stelljes, M.; Mesters, R. M.; Serve, H. L.; Braess, J.; Spiekermann, K.; Staib, P.; Grüneisen, A.; Reichle, A.; Balleisen, L.; Eimermacher, H.; Giagounidis, A.; Rasche, H.; Lengfelder, E.; Görlich, D.; Faldum, A.; Köpcke, W.; Hehlmann, R.; Wörmann, B. J.; Berdel, W. E. und Hiddemann, W.
(2016):
Age, not therapy intensity, determines outcomes of adults with acute myeloid leukemia.
In: Leukemia, Bd. 30, Nr. 8: S. 1781-1784
2012
Greif, Philipp A.; Dufour, A.; Konstandin, Nikola P.; Ksienzyk, Bianka; Zellmeier, Evelyn; Tizazu, B.; Sturm, J.; Benthaus, T.; Herold, Tobias; Yaghmaie, M.; Dorge, P.; Hopfner, K. P.; Hauser, A.; Graf, A.; Krebs, S.; Blum, H.; Kakadia, P. M.; Schneider, S.; Hoster, Eva; Schneider, F.; Stanulla, M.; Braess, J.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Hiddemann, Wolfgang; Spiekermann, Karsten und Bohlander, Stefan K.
(2012):
GATA2 zinc finger 1 mutations associated with biallelic CEBPA mutations define a unique genetic entity of acute myeloid leukemia.
In: Blood, Bd. 120, Nr. 2: S. 395-403
Dufour, A.; Schneider, F.; Hoster, Eva; Benthaus, T.; Ksienzyk, Bianka; Schneider, S.; Kakadia, P. M.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Braess, J.; Subklewe, M.; Hiddemann, Wolfgang; Bohlander, Stefan K. und Spiekermann, Karsten
(2012):
Monoallelic CEBPA mutations in normal karyotype acute myeloid leukemia: independent favorable prognostic factor within NPM1 mutated patients.
In: Annals of Hematology, Bd. 91, Nr. 7: S. 1051-1063
Schneider, F.; Hoster, Eva; Unterhalt, Michael; Schneider, S.; Dufour, A.; Benthaus, T.; Mellert, G.; Zellmeier, Evelyn; Kakadia, P. M.; Bohlander, Stefan K.; Feuring-Buske, M.; Buske, C.; Braess, J.; Heinecke, A.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Hiddemann, Wolfgang und Spiekermann, Karsten
(2012):
The FLT3ITD level has a high prognostic impact in NPM1 mutated, but not NPM1 unmutated AML with a normal karyotype.
In: Blood, Bd. 119, Nr. 19: S. 4383-4386
Schneider, F.; Hoster, Eva; Schneider, S.; Dufour, A.; Benthaus, T.; Kakadia, P. M.; Bohlander, Stefan K.; Braess, J.; Heinecke, A.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Feuring-Buske, M.; Buske, C.; Creutzig, U.; Thiede, C.; Zwaan, M. C.; Heuvel-Eibrink, M. M. van den; Reinhardt, D.; Hiddemann, Wolfgang und Spiekermann, Karsten
(2012):
Age-dependent frequencies of NPM1 mutations and FLT3-ITD in patients with normal karyotype AML (NK-AML).
In: Annals of Hematology, Bd. 91, Nr. 1: S. 9-18
2011
Herold, Tobias; Jurinovic, Vindi; Mulaw, M.; Seiler, T.; Dufour, A.; Schneider, S.; Kakadia, P. M.; Feuring-Buske, M.; Braess, J.; Spiekermann, Karsten; Mansmann, Ulrich; Hiddemann, Wolfgang; Buske, C. und Bohlander, Stefan K.
(2011):
Expression analysis of genes located in the minimally deleted regions of 13q14 and 11q22-23 in chronic lymphocytic leukemia-unexpected expression pattern of the RHO GTPase activator ARHGAP20.
In: Genes, Chromosomes and Cancer, Bd. 50, Nr. 7: S. 546-558
Herold, Tobias; Jurinovic, Vindi; Metzeler, Klaus H.; Boulesteix, Anne-Laure; Bergmann, M.; Seiler, T.; Mulaw, M.; Thoene, S.; Dufour, A.; Pasalic, Z.; Schmidberger, Markus; Schmidt, M.; Schneider, S.; Kakadia, P. M.; Feuring-Buske, M.; Braess, J.; Spiekermann, Karsten; Mansmann, Ulrich; Hiddemann, Wolfgang; Buske, C. und Bohlander, Stefan K.
(2011):
An eight-gene expression signature for the prediction of survival and time to treatment in chronic lymphocytic leukemia.
In: Leukemia, Bd. 25, Nr. 10: S. 1639-1645
2010
Dufour, A.; Schneider, F.; Metzeler, Klaus H.; Hoster, Eva; Schneider, S.; Zellmeier, Evelyn; Benthaus, T.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Braess, J.; Hiddemann, Wolfgang; Bohlander, Stefan K. und Spiekermann, Karsten
(2010):
Acute myeloid leukemia with biallelic CEBPA gene mutations and normal karyotype represents a distinct genetic entity associated with a favorable clinical outcome.
In: Journal of Clinical Oncology, Bd. 28, Nr. 4: S. 570-577
2009
Metzeler, Klaus H.; Dufour, A.; Benthaus, T.; Hummel, Martina; Sauerland, M. C.; Heinecke, A.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Mansmann, Ulrich; Braess, J.; Spiekermann, Karsten; Hiddemann, Wolfgang; Buske, C. und Bohlander, Stefan K.
(2009):
ERG Expression Is an Independent Prognostic Factor and Allows Refined Risk Stratification in Cytogenetically Normal Acute Myeloid Leukemia: A Comprehensive Analysis of ERG, MN1, and BAALC Transcript Levels Using Oligonucleotide Microarrays.
In: Journal of Clinical Oncology, Bd. 27, Nr. 30: S. 5031-5038
Schneider, F.; Hoster, Eva; Unterhalt, Michael; Schneider, S.; Dufour, A.; Benthaus, T.; Mellert, G.; Zellmeier, Evelyn; Bohlander, Stefan K.; Feuring-Buske, M.; Buske, C.; Braess, J.; Fritsch, S.; Heinecke, A.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Hiddemann, Wolfgang und Spiekermann, Karsten
(2009):
NPM1, but not FLT3-ITD mutations predict early blast cell clearance and CR rate in patients with normal karyotype AML (NK-AML) or high risk myelodysplastic syndrome (MDS).
In: Blood, Bd. 113, Nr. 21: S. 5250-5253
Reiff, T.; Stingele, R.; Eckstein, H. H.; Fraedrich, G.; Jansen, O.; Mudra, H.; Mansmann, Ulrich; Hacke, W.; Ringleb, P. A.; Metzeler, Klaus H.; Dufour, A.; Benthaus, T.; Hummel, Martina; Sauerland, M. C.; Heinecke, A.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Braess, J.; Spiekermann, Karsten; Hiddemann, Wolfgang; Buske, C.; Bohlander, Stefan K.; Nagel, J. M.; Wegscheider, K.; Rohmel, J.; Fleckenstein, M.; Adrion, Christine ORCID: https://orcid.org/0000-0003-2408-2533; Schmitz-Valckenberg, S.; Gobel, A. P.; Bindewald-Wittich, A.; Scholl, H. und Holz, F.
(2009):
Stent-Protected Angioplasty in Asymptomatic Carotid Artery Stenosis vs. Endarterectomy: SPACE2 – a Three-Arm Randomised-Controlled Clinical Trial.
In: International Journal of Stroke, Bd. 4, Nr. 4: S. 294-299
2008
Metzeler, Klaus H.; Hummel, Martina; Bloomfield, C. D.; Spiekermann, Karsten; Braess, J.; Sauerland, M. C.; Heinecke, A.; Radmacher, M. D.; Marcucci, G.; Whitman, SP.; Maharry, K.; Paschka, P.; Larson, RA.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Mansmann, Ulrich; Hiddemann, Wolfgang; Bohlander, Stefan K. und Buske, C.
(2008):
An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia.
In: Blood, Bd. 112, Nr. 10: S. 4193-4201
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