Publikationen von Brand, Stephan

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Anzahl der Publikationen: 37

Zeitschriftenartikel

Stallhofer, Johannes; Veith, Lisa; Diegelmann, Julia; Probst, Philipp; Brand, Stephan; Schnitzler, Fabian; Olszak, Torsten; Toeroek, Helga; Mayerle, Julia; Stallmach, Andreas und Beigel, Florian (2022): Iron Deficiency in Inflammatory Bowel Disease Is Associated With Low Levels of Vitamin D Modulating Serum Hepcidin and Intestinal Ceruloplasmin Expression. In: Clinical and Translational Gastroenterology, Bd. 13, Nr. 1, e00450

Woelfel, Simon; Duetschler, Joel; Koenig, Marius; Graf, Nicole; Oikonomou, Vasileios; Krieger, Claudia; Truniger, Samuel; Franke, Annett; Eckhold, Annika; Forsch, Kristina; Wyss, Jacqueline; Krupka, Niklas; Albrich, Werner; Frei, Nicola; Geissler, Nora; Schaub, Peter; Friedrich, Matthias; Misselwitz, Benjamin; Korte, Wolfgang; Burgi, Justus J. und Brand, Stephan (2022): Systemic and T cell-associated responses to SARS-CoV-2 immunisation in gut inflammation (STAR SIGN study): effects of biologics on vaccination efficacy of the third dose of mRNA vaccines against SARS-CoV-2. In: Alimentary Pharmacology & Therapeutics, Bd. 57, Nr. 1: S. 103-116

Schnitzler, Fabian; Friedrich, Matthias; Angelberger, Marianne; Diegelmann, Julia; Stallhofer, Johannes; Wolf, Christiane; Dütschler, Joel; Truniger, Samuel; Olszak, Torsten; Beigel, Florian; Tillack, Cornelia; Lohse, Peter und Brand, Stephan (2020): Development of a uniform, very aggressive disease phenotype in all homozygous carriers of the NOD2 mutation p.Leu1007fsX1008 with Crohn's disease and active smoking status resulting in ileal stenosis requiring surgery.
In: PLOS One 15(7), e0236421 [PDF, 881kB]

Serra, Eva Goncalves; Schwerd, Tobias; Moutsianas, Loukas; Cavounidis, Athena; Fachal, Laura; Pandey, Sumeet; Kammermeier, Jochen; Croft, Nicholas M.; Posovszky, Carsten; Rodrigues, Astor; Russell, Richard K.; Barakat, Farah; Auth, Marcus K. H.; Heuschkel, Robert; Zilbauer, Matthias; Fyderek, Krzysztof; Braegger, Christian; Travis, Simon P.; Satsangi, Jack; Parkes, Miles; Thapar, Nikhil; Ferry, Helen; Matte, Julie C.; Gilmour, Kimberly C.; Wedrychowicz, Andrzej; Sullivan, Peter; Moore, Carmel; Sambrook, Jennifer; Ouwehand, Willem; Roberts, David; Danesh, John; Baeumler, Toni A.; Fulga, Tudor A.; Karaminejadranjbar, Mohammad; Ahmed, Ahmed; Wilson, Rachel; Barrett, Jeffrey C.; Elkadri, Abdul; Griffiths, Anne M.; Snapper, Scott B.; Shah, Neil; Muise, Aleixo M.; Wilson, David C.; Uhlig, Holm H.; Anderson, Carl A.; Zurek, Marlen; Strisciuglio, Caterina; Elawad, Mamoun; Lo, Bernice; Arancibia-Carcamo, Carolina; Bailey, Adam; Barnes, Ellie; Bird-Lieberman, Elizabeth Louise; Brain, Oliver; Braden, Barbara; Collier, Jane; East, James; Howarth, Lucy; Keshav, Satish; Klenerman, Paul; Leedham, Simon; Palmer, Rebecca; Powrie, Fiona; Simmons, Alison; Walker, Matthew; Tolkien, Zoe; Kaptoge, Stephen; Allen, David; Mehenny, Susan; Mant, Jonathan; Di Angelantonio, Emanuele; Thompson, Simon G.; Yilmaz, Bahtiyar; Juillerat, Pascal; Geuking, Markus; Wiest, Reiner; Macpherson, Andrew J.; Bravo, Francisco Damian; Brugger, Lukas; Carstens, Ove; Bigler, Ulrike Graf; Heimgartner, Benjamin; Rusticeanu, Monica; Schmid-Uebelhart, Sybille; Strebel, Bruno; Tatu, Aurora; Tutuian, Radu; Wiest, Reiner; Oyas, Ove; Ramon, Charlotte; Stelling, Jorg; Franc, Yannick; Fournier, Nicolas; Pittet, Valerie E. H.; Burnand, Bernard; Egger, Mara; Franc, Yannick; Golay, Delphine; Marot, Astrid; Musso, Leilla; Pittet, Valerie; Rossel, Jean-Benoit; Seematter, Vivianne; Sommer, Joachim; Vulliamy, Rachel; Michetti, Pierre; Maillard, Michel H.; Keller, Celine; Maillard, Michel H.; Nydegger, Andreas; Schoepfe, Alain; Archanioti, Eva; Ezri, Jessica; Fraga, Montserrat; Schoepfer, Alain; Müller, Christoph; Rogler, Gerhard; Biedermann, Luc; Blattmann, Mirjam; Burk, Sabine; Dora, Barbara; Fried, Michael; Misselwitz, Benjamin; Mullhaupt, Beat; Obialo, Nicole; Pohl, Daniel; Raschle, Nadia; Rogler, Gerhard; Scharl, Michael; Vavricka, Stephan; Kanel, Roland von; Zeitz, Jonas; Abdelrahman, Karim; Ademi, Gentiana; Borovicka, Jan; Brand, Stephan; Frei, Remus; Haarer, Johannes; Grieger, Christina Knellwolf; Krieger-Grubel, Claudia; Kunzler, Patrizia; Meyenberger, Christa; Meyer, Pamela; Rohrich, Nina; Sawatzki, Mikael; Schelling, Martin; Semadeni, Gian-Marco; Sulz, Michael; Zimmermann, Dorothee; Aepli, Patrick; Criblez, Dominique H.; Hess, Cyrill; Richterich, Jean-Pierre; Spalinger, Johannes; Staudenmann, Dominic; Stulz, Andreas; Wohrle, Stefanie; Thomas, Amman; Anderegg, Claudia; Kohler, Henrik; Kusche, Rachel; Antonino, Anca-Teodora; Arrigoni, Eviano; Bengoa, Jose M.; Cunningham, Sophie; de Saussure, Philippe; Girard, Laurent; Bakker de Jong, Diana; Basturk, Polat; Brunner, Simon; Degen, Lukas; Hruz, Petr; Khalid-de Bakker, Carolina; Niess, Jan; Balsiger, Bruno; Haldemann, Janine; Saner, Gaby; Seibold, Frank; Bauerfeind, Peter; Becocci, Andrea; Belli, Dominique; Binek, Janek; Hengstler, Peter; Boehm, Stephan; Boldanov, Tujana; Buhr, Patrick; Koller, Rebekka; Rueger, Vanessa; Senning, Arne; Burri, Emanuel; Buyse, Sophie; Cao, Dahlia-Thao; D'Angelo, Fabrizia; Delarive, Joakim; Doerig, Christopher; Hessler, Roxane; Preissler, Claudia; Rentsch, Ronald; Risti, Branislav; Ritz, Marc Alain; Steuerwald, Michael; Vogtlin, Jurg; Sagmeister, Markus; Sauter, Bernhard; Schibli, Susanne; Sokollik, Christiane; Spalinger, Johannes; Schlauri, Hugo; Schnegg, Jean-Francois; Seirafi, Mariam; Spangenberger, Holger; Stadler, Philippe; Staub, Peter; Stenz, Volker; Tempia-Caliera, Michela; Thorens, Joel; Truninger, Kaspar; Urfer, Patrick; Viani, Francesco; Vouillamoz, Dominique; Zander, Silvan; Wyli, Tina; Jostins, L.; Kennedy, N. A.; Ahmad, T.; Lamb, C. A.; Edwards, C.; Hart, A.; Hawkey, C.; Mansfield, J. C.; Mowat, C.; Newman, W. G.; Simmons, A.; Tremelling, M.; Lee, J. C.; Prescott, N. J.; Mathew, C. G.; Lees, C. W.; McGovern, D. P. B.; Targan, S. R.; Botwin, G.; Mengesha, E.; Fleshner, P.; Landers, C.; Li, D.; Rioux, J. D.; Bitton, A.; Cote-Daigneault, J.; Daly, M. J.; Xavier, R.; Morris, K.; Boucher, G.; Cho, J. H.; Abraham, C.; Merad, M.; Sands, B.; Peter, I.; Hao, K.; Itan, Y.; Duerr, R. H.; Konnikova, L.; Schwartz, M. B.; Proksell, S.; Johnston, E.; Miladinova, V.; Chen, W.; Brant, S. R.; Datta, L.; Silverberg, M. S.; Schumm, L. P.; Birch, S.; Giri, M.; Gettler, K.; Sharma, Y.; Stevens, C.; Lazarev, M. und Haritunians, T. (2020): Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease. In: Nature Communications, Bd. 11, Nr. 1, 995 [PDF, 1MB]

Momozawa, Yukihide; Dmitrieva, Julia; Theatre, Emilie; Deffontaine, Valerie; Brand, Stephan; Glas, Jürgen und Winkelmann, Juliane (2018): IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes. In: Nature Communications, Bd. 9, 2427 [PDF, 1MB]

Török, Helga Paula; Bellon, Victor; Konrad, Astrid; Lacher, Martin; Tonenchi, Laurian; Siebeck, Matthias; Brand, Stephan und Toni, Enrico Narciso de (2017): Functional Toll-Like Receptor (TLR) 2 polymorphisms in the susceptibility to inflammatory bowel disease.
In: PLOS One 12(4), e0175180 [PDF, 1MB]

Flachsbart, Friederike; Ellinghaus, David; Gentschew, Liljana; Heinsen, Femke-Anouska; Caliebe, Amke; Christiansen, Lene; Nygaard, Marianne; Christensen, Kaare; Blanche, Helene; Deleuze, Jean-Francois; Derbois, Celine; Galan, Pilar; Büning, Carsten; Brand, Stephan; Peters, Annette

; Strauch, Konstantin; Müller-Nurasyid, Martina; Hoffmann, Per; Nöthen, Markus M.; Lieb, Wolfgang; Franke, Andre; Schreiber, Stefan und Nebel, Almut (2016): Immunochip analysis identifies association of the RAD50/IL13 region with human longevity. In: Aging Cell, Bd. 15, Nr. 3: S. 585-588 [PDF, 187kB]

Cleynen, Isabelle; Boucher, Gabrielle; Jostins, Luke; Schumm, L. Philip; Zeissig, Sebastian; Ahmad, Tariq; Andersen, Vibeke; Andrews, Jane M.; Annese, Vito; Brand, Stephan; Brant, Steven R.; Cho, Judy H.; Daly, Mark J.; Dubinsky, Marla; Duerr, Richard H.; Ferguson, Lynnette R.; Franke, Andre; Gearry, Richard B.; Goyette, Philippe; Hakonarson, Hakon; Halfvarson, Jonas; Hov, Johannes R.; Huang, Hailang; Kennedy, Nicholas A.; Kupcinskas, Limas; Lawrance, Ian C.; Lee, James C.; Satsangi, Jack; Schreiber, Stephan; Théâtre, Emilie; Meulen-de Jong, Andrea E. van der; Weersma, Rinse K.; Wilson, David C.; Parkes, Miles; Vermeire, Severine; Rioux, John D.; Mansfield, John; Silverberg, Mark S.; Radford-Smith, Graham; McGovern, Dermot P. B.; Barrett, Jeffrey C. und Lees, Charlie W. (2016): Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study. In: Lancet, Bd. 387, Nr. 10014: S. 156-167

Li, Dalin; Achkar, Jean-Paul; Haritunians, Talin; Jacobs, Jonathan P.; Hui, Ken Y.; D'Amato, Mauro; Brand, Stephan; Radford-Smith, Graham; Halfvarson, Jonas; Niess, Jan-Hendrik; Kugathasan, Subra; Büning, Carsten; Schumm, L. Philip; Klei, Lambertus; Ananthakrishnan, Ashwin; Aumais, Guy; Baidoo, Leonard; Dubinsky, Marla; Fiocchi, Claudio; Glas, Jürgen; Milgrom, Raquel; Proctor, Deborah D.; Regueiro, Miguel; Simms, Lisa A.; Stempak, Joanne M.; Targan, Stephan R.; Torkvist, Leif; Sharma, Yashoda; Devlin, Bernie; Borneman, James; Hakonarson, Hakon; Xavier, Ramnik J.; Daly, Mark; Brant, Steven R.; Rioux, John D.; Silverberg, Mark S.; Cho, Judy H.; Braun, Jonathan; McGovern, Dermot P. B. und Duerr, Richard H. (2016): A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition. In: Gastroenterology, Bd. 151, Nr. 4: S. 724-732

Li, Jin; Jørgensen, Silje F.; Maggadottir, S. Melkorka; Bakay, Marina; Warnatz, Klaus; Glessner, Joseph; Pandey, Rahul; Salzer, Ulrich; Schmidt, Reinhold E.; Perez, Elena; Resnick, Elena; Goldacker, Sigune; Buchta, Mary; Witte, Torsten; Padyukov, Leonid; Videm, Vibeke; Folseraas, Trine; Atschekzei, Faranaz; Elder, James T.; Nair, Rajan P.; Winkelmann, Juliane; Gieger, Christian; Nöthen, Markus M.; Büning, Carsten; Brand, Stephan; Sullivan, Kathleen E.; Orange, Jordan S.; Fevang, Børre; Schreiber, Stefan; Lieb, Wolfgang; Aukrust, Pål; Chapel, Helen; Cunningham-Rundles, Charlotte; Franke, Andre; Karlsen, Tom H.; Grimbacher, Bodo; Hakonarson, Hakon; Hammarström, Lennart und Ellinghaus, Eva (2015): Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells. In: Nature Communications, Bd. 6, 6804 [PDF, 807kB]

Schnitzler, Fabian; Friedrich, Matthias; Wolf, Christiane; Stallhofer, Johannes; Angelberger, Marianne; Diegelmann, Julia; Olszak, Torsten; Tillack, Cornelia; Beigel, Florian; Goeke, Burkhard; Glas, Jürgen; Lohse, Peter und Brand, Stephan (2015): The NOD2 Single Nucleotide Polymorphism rs72796353 (IVS4+10 A > C) Is a Predictor for Perianal Fistulas in Patients with Crohn's Disease in the Absence of Other NOD2 Mutations.
In: PLOS ONE 10(7), e0116044 [PDF, 233kB]

Schnitzler, Fabian; Friedrich, Matthias; Stallhofer, Johannes; Schoenermarck, Ulf; Fischereder, Michael; Habicht, Antje; Karbalai, Nazanin; Wolf, Christiane; Angelberger, Marianne; Olszak, Torsten; Beigel, Florian; Tillack, Cornelia; Goeke, Burkhard; Zachoval, Reinhart; Denk, Gerald; Guba, Markus; Rust, Christian; Gruener, Norbert und Brand, Stephan (2015): Solid Organ Transplantation in Patients with Inflammatory Bowel Diseases (IBD): Analysis of Transplantation Outcome and IBD Activity in a Large Single Center Cohort.
In: PLOS ONE 10(8), e0135807 [PDF, 545kB]

Tillack, Cornelia; Ehmann, Laura Maximiliane; Friedrich, Matthias; Laubender, Ruediger P.; Papay, Pavol; Vogelsang, Harald; Stallhofer, Johannes; Beigel, Florian; Bedynek, Andrea; Wetzke, Martin; Maier, Harald; Koburger, Maria; Wagner, Johanna; Glas, Jürgen; Diegelmann, Julia; Koglin, Sarah; Dombrowski, Yvonne; Schauber, Jürgen; Wollenberg, Andreas und Brand, Stephan (2014): Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-gamma-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment. In: Gut, Bd. 63, Nr. 4: S. 567-577 [PDF, 1MB]

Beigel, Florian; Friedrich, Matthias; Probst, Corina; Sotlar, Karl; Göke, Burkhard; Diegelmann, Julia und Brand, Stephan (2014): Oncostatin M Mediates STAT3-Dependent Intestinal Epithelial Restitution via Increased Cell Proliferation, Decreased Apoptosis and Upregulation of SERPIN Family Members.
In: PLOS ONE 9(4), e93498 [PDF, 3MB]

Beigel, Florian; Deml, Matthias; Schnitzler, Fabian; Breiteneicher, Simone; Göke, Burkhard; Ochsenkühn, Thomas und Brand, Stephan (2014): Rate and Predictors of Mucosal Healing in Patients with Inflammatory Bowel Disease Treated with Anti-TNF-Alpha Antibodies.
In: PLOS ONE 9(6), e99293 [PDF, 509kB]

Schnitzler, Fabian; Friedrich, Matthias; Wolf, Christiane; Angelberger, Marianne; Diegelmann, Julia; Olszak, Torsten; Beigel, Florian; Tillack, Cornelia; Stallhofer, Johannes; Göke, Burkhard; Glas, Jürgen; Lohse, Peter und Brand, Stephan (2014): The NOD2 p.Leu1007fsX1008 Mutation (rs2066847) Is a Stronger Predictor of the Clinical Course of Crohn's Disease than the FOXO3A Intron Variant rs12212067.
In: PLOS ONE 9(11), e108503 [PDF, 220kB]

Tillack, Cornelia; Ehmann, Laura Maximiliane; Friedrich, Matthias; Laubender, Rüdiger P.; Papay, Pavol; Vogelsang, Harald; Stallhofer, Johannes; Beigel, Florian; Bedynek, Andrea; Wetzke, Martin; Maier, Harald; Koburger, Maria; Wagner, Johanna; Glas, Jürgen; Diegelmann, Julia; Koglin, Sarah; Dombrowski, Yvonne; Schauber, Jürgen; Wollenberg, Andreas und Brand, Stephan (2014): Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-gamma-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment. In: Gut, Bd. 63, Nr. 4: S. 567-577

Brand, Stephan (November 2013): Moving the genetics of inflammatory bowel diseases from bench to bedside: first steps towards personalised medicine. In: Gut, Bd. 62, Nr. 11: S. 1531-1533 [PDF, 666kB]

Glas, Jürgen; Seiderer, Julia; Bues, Stephanie; Stallhofer, Johannes; Fries, Christoph; Olszak, Torsten; Tsekeri, Eleni; Wetzke, Martin; Beigel, Florian; Steib, Christian; Friedrich, Matthias; Göke, Burkhard; Diegelmann, Julia; Czamara, Darina und Brand, Stephan (2013): IRGM variants and susceptibility to inflammatory bowel disease in the German population.
In: PLOS ONE 8(1), e54338 [PDF, 214kB]

Beigel, Florian; Löhr, Beate; Laubender, Rüdiger P.; Tillack, Cornelia; Schnitzler, Fabian; Breiteneicher, Simone; Weidinger, Maria; Göke, Burkhard; Seiderer, Julia; Ochsenkühn, Thomas und Brand, Stephan (2012): Iron Status and Analysis of Efficacy and Safety of Ferric Carboxymaltose Treatment in Patients with Inflammatory Bowel Disease. In: Digestion, Nr. 1: S. 47-54 [PDF, 464kB]

Glas, Jürgen; Seiderer, Julia; Czamara, Darina; Pasciuto, Giulia; Diegelmann, Julia; Wetzke, Martin; Olszak, Torsten; Wolf, Christiane; Müller-Myhsok, Bertram; Balschun, Tobias; Achkar, Jean-Paul; Kamboh, M. Ilyas; Franke, Andre; Duerr, Richard H. und Brand, Stephan (2012): PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites.
In: PLOS ONE 7(12), e52873 [PDF, 206kB]

Glas, Jürgen; Wagner, Johanna; Seiderer, Julia; Olszak, Torsten; Wetzke, Martin; Beigel, Florian; Tillack, Cornelia; Stallhofer, Johannes; Friedrich, Matthias; Steib, Christian; Göke, Burkhard; Ochsenkühn, Thomas; Karbalai, Nazanin; Diegelmann, Julia; Czamara, Darina und Brand, Stephan (2012): PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background.
In: PLOS ONE 7(3), e33682 [PDF, 145kB]

Glas, Jürgen; Seiderer, Julia; Wagner, Johanna; Olszak, Torsten; Fries, Christoph; Tillack, Cornelia; Friedrich, Matthias; Beigel, Florian; Stallhofer, Johannes; Steib, Christian; Wetzke, Martin; Göke, Burkhard; Ochsenkühn, Thomas; Diegelmann, Julia; Czamara, Darina und Brand, Stephan (2012): Analysis of IL12B gene variants in inflammatory bowel disease.
In: PLOS ONE 7(3), e34349 [PDF, 136kB]

Rust, Christian und Brand, Stephan (September 2011): PSC: Protect and serve with colitis: does it help the liver to have severe ulcerative colitis? In: Gut, Bd. 60, Nr. 9: S. 1165-1166 [PDF, 78kB]

Stallhofer, Johannes; Denk, Gerald Ulrich; Glas, Jürgen; Laubender, Rüdiger Paul; Göke, Burkhard; Rust, Christian; Brand, Stephan und Pusl, Thomas (2011): Analysis of IL2/IL21 Gene Variants in Cholestatic Liver Diseases Reveals an Association with Primary Sclerosing Cholangitis. In: Digestion, Nr. 1: S. 29-35 [PDF, 156kB]

Glas, Jürgen; Seiderer, Julia; Bayrle, Corinna; Wetzke, Martin; Fries, Christoph; Tillack, Cornelia; Olszak, Torsten; Beigel, Florian; Steib, Christian; Friedrich, Matthias; Diegelmann, Julia; Czamara, Darina und Brand, Stephan (2011): The role of osteopontin (OPN/SPP1) haplotypes in the susceptibility to Crohn's disease.
In: PLOS ONE 6(12), e29309 [PDF, 129kB]

Glas, Jürgen; Seiderer, Julia; Fries, Christoph; Tillack, Cornelia; Pfennig, Simone; Weidinger, Maria; Beigel, Florian; Olszak, Torsten; Lass, Ulrich; Göke, Burkhard; Ochsenkühn, Thomas; Wolf, Christiane; Lohse, Peter; Müller-Myhsok, Bertram; Diegelmann, Julia; Czamara, Darina und Brand, Stephan (2011): CEACAM6 gene variants in inflammatory bowel disease.
In: PLOS ONE 6(4), e19319 [PDF, 214kB]

Jürgens, Matthias; Laubender, Rüdiger P.; Hartl, F.; Weidinger, M.; Seiderer, Julia; Wagner, J.; Wetzke, M.; Beigel, Florian; Pfennig, S.; Stallhofer, J.; Schnitzler, Fabian; Tillack, Cornelia; Lohse, Peter; Göke, Burkhard; Glas, Jürgen; Ochsenkühn, Thomas und Brand, Stephan (2010): Disease Activity, ANCA, and IL23R Genotype Status Determine Early Response to Infliximab in Patients With Ulcerative Colitis. In: American Journal of Gastroenterology, Bd. 105, Nr. 8: S. 1811-1819

Glas, Jürgen; Seiderer, Julia; Nagy, Melinda; Fries, Christoph; Beigel, Florian; Weidinger, Maria; Pfennig, Simone; Klein, Wolfram; Epplen, Jörg T.; Lohse, Peter; Folwaczny, Matthias; Göke, Burkhard; Ochsenkühn, Thomas; Diegelmann, Julia; Müller-Myhsok, Bertram; Roeske, Darina und Brand, Stephan (2010): Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset.
In: PLOS ONE 5(4), e10373 [PDF, 128kB]

Diegelmann, Julia; Beigel, Florian; Zitzmann, Kathrin; Kaul, Artur; Göke, Burkhard; Auernhammer, Christoph J.; Bartenschlager, Ralf; Diepolder, Helmut M. und Brand, Stephan (2010): Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus.
In: PLOS ONE 5(12), e15200 [PDF, 572kB]

Glas, Jürgen; Seiderer, Julia; Tillack, Cornelia; Pfennig, Simone; Beigel, Florian; Jürgens, Matthias; Olszak, Torsten; Laubender, Rüdiger P.; Weidinger, Maria; Müller-Myhsok, Bertram; Göke, Burkhard; Ochsenkühn, Thomas; Lohse, Peter; Diegelmann, Julia; Czamara, Darina und Brand, Stephan (2010): The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants.
In: PLOS ONE 5(12), e14466 [PDF, 125kB]

Storr, Martin; Emmerdinger, Dominik; Diegelmann, Julia; Pfennig, Simone; Ochsenkühn, Thomas; Göke, Burkhard; Lohse, Peter und Brand, Stephan (2010): The cannabinoid 1 receptor (CNR1) 1359 G/A polymorphism modulates susceptibility to ulcerative colitis and the phenotype in Crohn's disease.
In: PLOS ONE 5(2), e9453 [PDF, 106kB]

Brand, Stephan (2009): Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease. In: Gut, Bd. 58, Nr. 8: S. 1152-1167 [PDF, 1MB]

Dambacher, J.; Beigel, Florian; Zitzmann, K.; Toni, Enrico N. de; Göke, Burkhard; Diepolder, Helmut M.; Auernhammer, Christoph J. und Brand, Stephan (2009): The role of the novel Th17 cytokine IL-26 in intestinal inflammation. In: Gut, Bd. 58, Nr. 9: S. 1207-1217 [PDF, 4MB]

Glas, Jürgen; Seiderer, Julia; Wetzke, Martin; Konrad, Astrid; Török, Helga-Paula; Schmechel, Silke; Tonenchi, Laurian; Grassl, Christine; Dambacher, Julia; Pfennig, Simone; Maier, Kerstin; Griga, Thomas; Klein, Wolfram; Epplen, Jörg T.; Schiemann, Uwe; Folwaczny, Christian; Lohse, Peter; Göke, Burkhard; Ochsenkühn, Thomas; Müller-Myhsok, Bertram; Folwaczny, Matthias; Mussack, Thomas und Brand, Stephan (2007): rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants.
In: PLOS ONE (9), e819 [PDF, 133kB]

Dambacher, Julia; Beigel, Florian; Seiderer, Julia; Haller, Dirk; Göke, Burkhard; Auernhammer, Christoph J. und Brand, Stephan (2007): Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease. In: Gut, Bd. 56, Nr. 9: S. 1257-1265 [PDF, 559kB]

Zitzmann, Kathrin; De Toni, Enrico N.; Brand, Stephan; Göke, Burkhard; Meinecke, Jennifer; Spoettl, Gerald; Meyer, Heinrich H. D. und Auernhammer, Christoph J. (2007): The novel mTOR inhibitor RAD001 (Everolimus) induces antiproliferative effects in human pancreatic neuroendocrine tumor cells. In: Neuroendocrinology, Nr. 1: S. 54-60 [PDF, 222kB]

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