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Anzahl der Publikationen: 30
Zeitschriftenartikel
Leidescher, Susanne; Ribisel, Johannes; Ullrich, Simon; Feodorova, Yana; Hildebrand, Erica; Galitsyna, Alexandra; Bultmann, Sebastian; Link, Stephanie; Thanisch, Katharina; Mulholland, Christopher; Dekker, Job; Leonhardt, Heinrich; Mirny, Leonid und Solovei, Irina
(2022):
Spatial organization of transcribed eukaryotic genes.
In: Nature Cell Biology, Bd. 24, Nr. 3: S. 327-339
Stolz, Paul; Mantero, Angelo Salazar; Tvardovskiy, Andrey; Ugur, Enes; Wange, Lucas E.; Mulholland, Christopher B.; Cheng, Yuying; Wierer, Michael; Enard, Wolfgang; Schneider, Robert; Bartke, Till; Leonhardt, Heinrich; Elsasser, Simon J. und Bultmann, Sebastian
(2022):
TET1 regulates gene expression and repression of endogenous retroviruses independent of DNA demethylation.
In: Nucleic Acids Research, Bd. 50, Nr. 15: S. 8491-8511
[PDF, 4MB]
Qin, Weihua; Ugur, Enes; Mulholland, Christopher B.; Bultmann, Sebastian; Solovei, Irina; Modic, Miha; Smets, Martha; Wierer, Michael; Forne, Ignasi; Imhof, Axel; Cardoso, M. Cristina und Leonhardt, Heinrich
(2021):
Phosphorylation of the HP1 beta hinge region sequesters KAP1 in heterochromatin and promotes the exit from naive pluripotency.
In: Nucleic Acids Research, Bd. 49, Nr. 13: S. 7406-7423
Petryk, Nataliya; Bultmann, Sebastian; Bartke, Till und Defossez, Pierre-Antoine
(2021):
Staying true to yourself: mechanisms of DNA methylation maintenance in mammals.
In: Nucleic Acids Research, Bd. 49, Nr. 6: S. 3020-3032
Kempf, Julia M.; Weser, Sabrina; Bartoschek, Michael D.; Metzeler, Klaus H.; Vick, Binje; Herold, Tobias; Voelse, Kerstin; Mattes, Raphael; Scholz, Manuela; Wange, Lucas E.; Festini, Moreno; Ugur, Enes; Roas, Maike; Weigert, Oliver; Bultmann, Sebastian; Leonhardt, Heinrich; Schotta, Gunnar; Hiddemann, Wolfgang; Jeremias, Irmela und Spiekermann, Karsten
(2021):
Loss-of-function mutations in the histone methyltransferase EZH2 promote chemotherapy resistance in AML.
In: Scientific Reports, Bd. 11, Nr. 1, 5838
Gavins, Georgina C.; Groger, Katharina; Reimann, Marc; Bartoschek, Michael D.; Bultmann, Sebastian und Seitz, Oliver
(2021):
Orthogonal coiled coils enable rapid covalent labelling of two distinct membrane proteins with peptide nucleic acid barcodes.
In: Rsc Chemical Biology, Bd. 2, Nr. 4: S. 1291-1295
Bartoschek, Michael D.; Ugur, Enes; Nguyen, Tuan-Anh; Rodschinka, Geraldine; Wierer, Michael; Lang, Kathrin und Bultmann, Sebastian
(2021):
Identification of permissive amber suppression sites for efficient non-canonical amino acid incorporation in mammalian cells.
In: Nucleic Acids Research, Bd. 49, Nr. 11, e62
Ignatova, Valentina V.; Stolz, Paul; Kaiser, Steffen; Gustafsson, Tobias H.; Lastres, Palma Rico; Sanz-Moreno, Adrian; Cho, Yi-Li; Amarie, Oana V.; Aguilar-Pimentel, Antonio; Klein-Rodewald, Tanja; Calzada-Wack, Julia; Becker, Lore; Marschall, Susan; Kraiger, Markus; Garrett, Lillian; Seisenberger, Claudia; Hoelter, Sabine M.; Borland, Kayla; Logt, Erik van de; Jansen, Pascal W. T. C.; Baltissen, Marijke P.; Valenta, Magdalena; Vermeulen, Michiel; Wurst, Wolfgang; Gailus-Durner, Valerie; Fuchs, Helmut; Hrabe de Angelis, Martin; Rando, Oliver J.; Kellner, Stefanie M.; Bultmann, Sebastian und Schneider, Robert
(2020):
The rRNA m(6)A methyltransferase METTL5 is involved in pluripotency and developmental programs.
In: Genes & Development, Bd. 34: S. 715-729
[PDF, 4MB]
Bararia, Deepak; Hildebrand, Johannes A.; Stolz, Sebastian; Haebe, Sarah; Alig, Stefan; Trevisani, Christopher P.; Osorio-Barrios, Francisco; Bartoschek, Michael D.; Mentz, Michael; Pastore, Alessandro; Gaitzsch, Erik; Heide, Michael; Jurinovic, Vindi; Rautter, Katharina; Gunawardana, Jay; Sabdia, Muhammed B.; Szczepanowski, Monika; Richter, Julia; Klapper, Wolfram; Louissaint, Abner; Ludwig, Christina; Bultmann, Sebastian; Leonhardt, Heinrich; Eustermann, Sebastian; Hopfner, Karl-Peter; Hiddemann, Wolfgang; Bergwelt-Baildon, Michael von; Steidl, Christian; Kridel, Robert; Tobin, Joshua W. D.; Gandhi, Maher K.; Weinstock, David M.; Schmidt-Supprian, Marc; Sarosi, Menyhart B.; Rudelius, Martina; Passerini, Verena; Mautner, Josef und Weigert, Oliver
(2020):
Cathepsin S Alterations Induce a Tumor-Promoting Immune Microenvironment in Follicular Lymphoma.
In: Cell Reports, Bd. 31, Nr. 5, 107522
Gavins, Georgina C.; Gröger, Katharina; Bartoschek, Michael D.; Wolf, Philipp; Beck-Sickinger, Annette G.; Bultmann, Sebastian und Seitz, Oliver
(2020):
Live cell PNA labelling enables erasable fluorescence imaging of membrane proteins.
In: Nature Chemistry, Bd. 13, Nr. 1: S. 15-23
Nishiyama, Atsuya; Mulholland, Christopher B.; Bultmann, Sebastian; Kori, Satomi; Endo, Akinori; Saeki, Yasushi; Qin, Weihua; Trummer, Carina; Chiba, Yoshie; Yokoyama, Haruka; Kumamoto, Soichiro; Kawakami, Toru; Hojo, Hironobu; Nagae, Genta; Aburatani, Hiroyuki; Tanaka, Keiji; Arita, Kyohei; Leonhardt, Heinrich und Nakanishi, Makoto
(2020):
Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation.
In: Nature Communications, Bd. 11, Nr. 1, 1222
[PDF, 3MB]
Stief, Sophie M.; Hanneforth, Anna-Li; Weser, Sabrina; Mattes, Raphael; Carlet, Michela; Liu, Wen-Hsin; Bartoschek, Michael D.; Moreno, Helena Dominguez; Oettle, Matthias; Kempf, Julia; Vick, Binje; Ksienzyk, Bianka; Tizazu, Belay; Rothenberg-Thurley, Maja; Quentmeier, Hilmar; Hiddemann, Wolfgang; Vosberg, Sebastian; Greif, Philipp A.; Metzeler, Klaus H.; Schotta, Gunnar; Bultmann, Sebastian; Jeremias, Irmela; Leonhardt, Heinrich und Spiekermann, Karsten
(2020):
Loss of KDM6A confers drug resistance in acute myeloid leukemia.
In: Leukemia, Bd. 34, Nr. 1: S. 50-62
Mulholland, Christopher B.; Traube, Franziska R.; Ugur, Enes; Parsa, Edris; Eckl, Eva-Maria; Schoenung, Maximilian; Modic, Miha; Bartoschek, Michael D.; Stolz, Paul; Ryan, Joel; Carell, Thomas; Leonhardt, Heinrich und Bultmann, Sebastian
(2020):
Distinct and stage-specific contributions of TET1 and TET2 to stepwise cytosine oxidation in the transition from naive to primed pluripotency.
In: Scientific Reports, Bd. 10, Nr. 1, 12066
[PDF, 1MB]
Ignatova, Valentina V.; Kaiser, Steffen; Ho, Jessica Sook Yuin; Bing, Xinyang; Stolz, Paul; Tan, Ying Xim; Lee, Chee Leng; Gay, Florence Pik Hoon; Lastres, Palma Rico; Gerlini, Raffaele; Rathkolb, Birgit; Aguilar-Pimentel, Antonio; Sanz-Moreno, Adrian; Klein-Rodewald, Tanja; Calzada-Wack, Julia; Ibragimov, Emil; Valenta, Magdalena; Lukauskas, Saulius; Pavesi, Andrea; Marschall, Susan; Leuchtenberger, Stefanie; Fuchs, Helmut; Gailus-Durner, Valerie; De Angelis, Martin Hrabe; Bultmann, Sebastian; Rando, Oliver J.; Guccione, Ernesto; Kellner, Stefanie M. und Schneider, Robert
(2020):
METTL6 is a tRNA m(3)C methyltransferase that regulates pluripotency and tumor cell growth.
In: Science Advances, Bd. 6, Nr. 35, eaaz4551
Mulholland, Christopher B.; Nishiyama, Atsuya; Ryan, Joel; Nakamura, Ryohei; Yigit, Merve; Glueck, Ivo M.; Trummer, Carina; Qin, Weihua; Bartoschek, Michael D.; Traube, Franziska R.; Parsa, Edris; Ugur, Enes; Modic, Miha; Acharya, Aishwarya; Stolz, Paul; Ziegenhain, Christoph; Wierer, Michael; Enard, Wolfgang; Carell, Thomas; Lamb, Don C.; Takeda, Hiroyuki; Nakanashi, Makoto; Bultmann, Sebastian und Leonhardt, Heinrich
(2020):
Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals.
In: Nature Communications, Bd. 11, Nr. 1, 5972
[PDF, 8MB]
Götzl, Julia K.; Brendel, Matthias; Werner, Georg; Parhizkar, Samira; Monasor, Laura Sebastian; Kleinberger, Gernot; Colombo, Alessio‐Vittorio; Deussing, Maximilian; Wagner, Matias; Winkelmann, Juliane; Diehl‐Schmid, Janine; Levin, Johannes; Fellerer, Katrin; Reifschneider, Anika; Bultmann, Sebastian; Bartenstein, Peter; Rominger, Axel; Tahirovic, Sabina; Smith, Scott T.; Madore, Charlotte; Butovsky, Oleg; Capell, Anja und Haass, Christian
(2019):
Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism.
In: Embo Molecular Medicine, Bd. 11, Nr. 6
[PDF, 1MB]
Gasparoni, Gilles; Bultmann, Sebastian; Lutsik, Pavlo; Kraus, Theo F. J.; Sordon, Sabrina; Vlcek, Julia; Dietinger, Vanessa; Steinmaurer, Martina; Haider, Melanie; Mulholland, Christopher B.; Arzberger, Thomas; Röber, Sigrun; Riemenschneider, Matthias; Kretzschmar, Hans A.; Giese, Armin; Leonhardt, Heinrich und Walter, Jörn
(2018):
DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
In: Epigenetics & Chromatin
11:41
[PDF, 6MB]
Foster, Benjamin M.; Stolz, Paul; Mulholland, Christopher B.; Montoya, Alex; Kramer, Holger; Bultmann, Sebastian und Bartke, Till
(2018):
Critical Role of the UBL Domain in Stimulating the E3 Ubiquitin Ligase Activity of UHRF1 toward Chromatin.
In: Molecular Cell, Bd. 72, Nr. 4: S. 739-752
Bultmann, Sebastian und Stricker, Stefan H.
(2018):
Entering the post-epigenomic age: back to epigenetics.
In: Open Biology, Bd. 8, Nr. 3, 180013
Hinrichs, Arne; Kessler, Barbara; Kurome, Mayuko; Blutke, Andreas; Kemter, Elisabeth; Bernau, Maren; Scholz, Armin M.; Rathkolb, Birgit; Renner, Simone; Bultmann, Sebastian; Leonhardt, Heinrich; Hrabe de Angelis, Martin; Nagashima, Hiroshi; Hoeflich, Andreas; Blum, Werner F.; Bidlingmaier, Martin; Wanke, Rüdiger; Dahlhoff, Maik und Wolf, Eckhard
(2018):
Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liver.
In: Molecular Metabolism, Bd. 11: S. 113-128
[PDF, 3MB]
Anton, Tobias und Bultmann, Sebastian
(2017):
Site-specific recruitment of epigenetic factors with a modular CRISPR/Cas system.
In: Nucleus, Bd. 8, Nr. 3: S. 279-286
[PDF, 1MB]
Dahlhoff, Maik; Gaborit, Nadege; Bultmann, Sebastian; Leonhardt, Heinrich; Yarden, Yosef und Schneider, Marlon R.
(2017):
CRISPR-assisted receptor deletion reveals distinct roles for ERBB2 and ERBB3 in skin keratinocytes.
In: FEBS Journal, Bd. 284, Nr. 19: S. 3339-3349
Mazaheri, Fargol; Snaidero, Nicolas; Kleinberger, Gernot; Madore, Charlotte; Daria, Anna; Werner, Georg; Krasemann, Susanne; Capell, Anja; Trümbach, Dietrich; Wurst, Wolfgang; Brunner, Bettina; Bultmann, Sebastian; Tahirovic, Sabina; Kerschensteiner, Martin; Misgeld, Thomas; Butovsky, Oleg und Haass, Christian 
ORCID: https://orcid.org/0000-0002-4869-1627
(2017):
TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.
In: Embo Reports, Bd. 18, Nr. 7: S. 1186-1198
ORCID: https://orcid.org/0000-0002-4869-1627
(2017):
TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.
In: Embo Reports, Bd. 18, Nr. 7: S. 1186-1198
Sellou, Hafida; Lebeaupin, Théo; Chapuis, Catherine; Smith, Rebecca; Hegele, Anna; Singh, Hari R.; Kozlowski, Marek; Bultmann, Sebastian; Ladurner, Andreas G.; Timinszky, Gyula und Huet, Sébastien
(2016):
The poly(ADP-ribose)-dependent chromatin remodeler Alc1 induces local chromatin relaxation upon DNA damage.
In: Molecular Biology of the Cell, Bd. 27, Nr. 24: S. 3791-3799
Mulholland, Christopher B.; Smets, Martha; Schmidtmann, Elisabeth; Leidescher, Susanne; Markaki, Yolanda; Hofweber, Mario; Qin, Weihua; Manzo, Massimiliano; Kremmer, Elisabeth; Thanisch, Katharina; Bauer, Christina; Rombaut, Pascaline; Herzog, Franz; Leonhardt, Heinrich und Bultmann, Sebastian
(2015):
A modular open platform for systematic functional studies under physiological conditions.
In: Nucleic Acids Research, Bd. 43, Nr. 17, e112
[PDF, 15MB]
Thanisch, Katharina; Schneider, Katrin; Morbitzer, Robert; Solovei, Irina; Lahaye, Thomas; Bultmann, Sebastian und Leonhardt, Heinrich
(2014):
Targeting and tracing of specific DNA sequences with dTALEs in living cells.
In: Nucleic Acids Research, Bd. 42, Nr. 6, e38
[PDF, 13MB]
Schmidt, Christine S.; Bultmann, Sebastian; Meilinger, Daniela; Zacher, Benedikt; Tresch, Achim; Maier, Kerstin C.; Peter, Christian; Martin, Dietmar E.; Leonhardt, Heinrich und Spada, Fabio
(2012):
Global DNA hypomethylation prevents consolidation of differentiation programs and allows reversion to the embryonic stem cell state.
In: PLOS ONE 7(12), e52629 [PDF, 1MB]
In: PLOS ONE 7(12), e52629 [PDF, 1MB]
Szwagierczak, Aleksandra; Brachmann, Andreas ORCID: https://orcid.org/0000-0001-7980-8173; Schmidt, Christine S.; Bultmann, Sebastian; Leonhardt, Heinrich und Spada, Fabio ORCID: https://orcid.org/0000-0002-7148-9013
(1. Juli 2011):
Characterization of PvuRts1I endonuclease as a tool to investigate genomic 5–hydroxymethylcytosine.
In: Nucleic Acids Research, Bd. 39, Nr. 12: S. 5149-5156
[PDF, 3MB]
ORCID: https://orcid.org/0000-0001-7980-8173; Schmidt, Christine S.; Bultmann, Sebastian; Leonhardt, Heinrich und Spada, Fabio ORCID: https://orcid.org/0000-0002-7148-9013
(1. Juli 2011):
Characterization of PvuRts1I endonuclease as a tool to investigate genomic 5–hydroxymethylcytosine.
In: Nucleic Acids Research, Bd. 39, Nr. 12: S. 5149-5156
[PDF, 3MB]
Frauer, Carina; Rottach, Andrea; Meilinger, Daniela; Bultmann, Sebastian; Fellinger, Karin; Hasenöder, Stefan; Wang, Mengxi; Qin, Weihua; Söding, Johannes; Spada, Fabio und Leonhardt, Heinrich
(2011):
Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1.
In: PLOS ONE 6(2), e16627 [PDF, 2MB]
In: PLOS ONE 6(2), e16627 [PDF, 2MB]
Frauer, Carina; Hoffmann, Thomas; Bultmann, Sebastian; Casa, Valentina; Cardoso, M. Cristina; Antes, Iris und Leonhardt, Heinrich
(2011):
Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain.
In: PLOS ONE 6(6), e21306 [PDF, 648kB]
In: PLOS ONE 6(6), e21306 [PDF, 648kB]