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Eine Ebene höherGruppiert nach: Dokumententyp |
Veröffentlichungsdatum
Anzahl der Publikationen: 19
2023
Gottschlich, Adrian; Thomas, Moritz; Gruenmeier, Ruth; Lesch, Stefanie; Rohrbacher, Lisa; Igl, Veronika; Briukhovetska, Daria; Benmebarek, Mohamed-Reda; Vick, Binje; Dede, Sertac; Mueller, Katharina; Xu, Tao; Dhoqina, Dario; Maerkl, Florian; Robinson, Sophie; Sendelhofert, Andrea; Schulz, Heiko; Umut, Oeykue; Kavaka, Vladyslav; Tsiverioti, Christina Angeliki; Carlini, Emanuele; Nandi, Sayantan; Strzalkowski, Thaddaeus; Lorenzini, Theo; Stock, Sophia; Mueller, Philipp Jie; Doerr, Janina; Seifert, Matthias; Cadilha, Bruno L.; Brabenec, Ruben; Roeder, Natalie; Rataj, Felicitas; Nueesch, Manuel; Modemann, Franziska; Wellbrock, Jasmin; Fiedler, Walter; Kellner, Christian; Beltran, Eduardo; Herold, Tobias; Paquet, Dominik; Jeremias, Irmela; von Baumgarten, Louisa; Endres, Stefan; Subklewe, Marion; Marr, Carsten und Kobold, Sebastian
(2023):
Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia.
In: Nature Biotechnology, Bd. 41, Nr. 11:
1618-+
[PDF, 7MB]
Lorenzini, Theo 
ORCID: https://orcid.org/0000-0003-3377-032X; Cadilha, Bruno L. ORCID: https://orcid.org/0000-0001-7045-3898; Obeck, Hannah; Benmebarek, Mohamed-Reda; Märkl, Florian ORCID: https://orcid.org/0000-0003-4285-0380; Michaelides, Stefanos; Strzalkowski, Thaddäus; Briukhovetska, Daria; Müller, Philipp Jie; Nandi, Sayantan; Winter, Pia; Majed, Lina; Grünmeier, Ruth ORCID: https://orcid.org/0000-0002-9044-3600; Seifert, Matthias ORCID: https://orcid.org/0000-0002-6581-6196; Rausch, Svenja; Feuchtinger, Tobias ORCID: https://orcid.org/0000-0002-8517-9681; Endres, Stefan ORCID: https://orcid.org/0000-0002-4703-537X und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2023):
Rational design of PD-1-CD28 immunostimulatory fusion proteins for CAR T cell therapy.
In: British Journal of Cancer, Bd. 129, Nr. 4: S. 696-705
[PDF, 2MB]
ORCID: https://orcid.org/0000-0003-3377-032X; Cadilha, Bruno L. ORCID: https://orcid.org/0000-0001-7045-3898; Obeck, Hannah; Benmebarek, Mohamed-Reda; Märkl, Florian ORCID: https://orcid.org/0000-0003-4285-0380; Michaelides, Stefanos; Strzalkowski, Thaddäus; Briukhovetska, Daria; Müller, Philipp Jie; Nandi, Sayantan; Winter, Pia; Majed, Lina; Grünmeier, Ruth ORCID: https://orcid.org/0000-0002-9044-3600; Seifert, Matthias ORCID: https://orcid.org/0000-0002-6581-6196; Rausch, Svenja; Feuchtinger, Tobias ORCID: https://orcid.org/0000-0002-8517-9681; Endres, Stefan ORCID: https://orcid.org/0000-0002-4703-537X und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2023):
Rational design of PD-1-CD28 immunostimulatory fusion proteins for CAR T cell therapy.
In: British Journal of Cancer, Bd. 129, Nr. 4: S. 696-705
[PDF, 2MB]
2022
Hoelting, Tilman L. B.; Cidre-Aranaz, Florencia; Matzek, Dana; Popper, Bastian; Jacobi, Severin J.; Funk, Cornelius M.; Geyer, Florian H.; Li, Jing; Piseddu, Ignazio; Cadilha, Bruno L.; Ledderose, Stephan; Zwilling, Jennifer; Ohmura, Shunya; Anz, David; Kuenkele, Annette; Klauschen, Frederick; Gruenewald, Thomas G. P. und Knott, Maximilian M. L.
(2022):
Neomorphic DNA-binding enables tumor-specific therapeutic gene expression in fusion-addicted childhood sarcoma.
In: Molecular Cancer, Bd. 21, Nr. 1, 199
Tokarew, Nicholas J.A.; Gosálvez, Javier Suárez; Nottebrock, Alessia; Briukhovestka, Daria; Endres, Stefan ORCID: https://orcid.org/0000-0002-4703-537X; Cadilha, Bruno L. und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2022):
Flow cytometry detection and quantification of CAR T cells into solid tumors.
In: Methods in Cell Biology, Bd. 167: S. 99-122
ORCID: https://orcid.org/0000-0002-4703-537X; Cadilha, Bruno L. und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2022):
Flow cytometry detection and quantification of CAR T cells into solid tumors.
In: Methods in Cell Biology, Bd. 167: S. 99-122
Seifert, Matthias; Benmebarek, Mohamed-Reda; Briukhovetska, Daria; Märkl, Florian; Dörr, Janina; Cadilha, Bruno L.; Jobst, Jakob; Stock, Sophia ORCID: https://orcid.org/0000-0002-5072-5013; Andreu-Sanz, David; Lorenzini, Theo; Grünmeier, Ruth ORCID: https://orcid.org/0000-0002-9044-3600; Oner, Arman; Obeck, Hannah; Majed, Lina; Dhoqina, Dario; Feinendegen, Manouk; Gottschlich, Adrian ORCID: https://orcid.org/0000-0002-2898-4182; Zhang, Jin; Schindler, Ulrike; Endres, Stefan ORCID: https://orcid.org/0000-0002-4703-537X und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2022):
Impact of the selective A2(A)R and A2(B)R dual antagonist AB928/etrumadenant on CAR T cell function.
In: British Journal of Cancer, Bd. 127, Nr. 12: S. 2175-2185
[PDF, 845kB]
ORCID: https://orcid.org/0000-0002-5072-5013; Andreu-Sanz, David; Lorenzini, Theo; Grünmeier, Ruth ORCID: https://orcid.org/0000-0002-9044-3600; Oner, Arman; Obeck, Hannah; Majed, Lina; Dhoqina, Dario; Feinendegen, Manouk; Gottschlich, Adrian ORCID: https://orcid.org/0000-0002-2898-4182; Zhang, Jin; Schindler, Ulrike; Endres, Stefan ORCID: https://orcid.org/0000-0002-4703-537X und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2022):
Impact of the selective A2(A)R and A2(B)R dual antagonist AB928/etrumadenant on CAR T cell function.
In: British Journal of Cancer, Bd. 127, Nr. 12: S. 2175-2185
[PDF, 845kB]
2021
Benmebarek, Mohamed-Reda; Cadilha, Bruno L.; Herrmann, Monika; Lesch, Stefanie; Schmitt, Saskia; Stoiber, Stefan; Darwich, Abbass; Augsberger, Christian; Brauchle, Bettina; Rohrbacher, Lisa; Oner, Arman; Seifert, Matthias; Schwerdtfeger, Melanie; Gottschlich, Adrian; Rataj, Felicitas; Fenn, Nadja C.; Klein, Christian; Subklewe, Marion; Endres, Stefan; Hopfner, Karl-Peter und Kobold, Sebastian
(2021):
A modular and controllable T cell therapy platform for acute myeloid leukemia.
In: Leukemia, Bd. 35, Nr. 8: S. 2243-2257
Prokopi, Anastasia; Tripp, Christoph H.; Tummers, Bart; Hornsteiner, Florian; Spoeck, Sarah; Crawford, Jeremy Chase; Clements, Derek R.; Efremova, Mirjana; Hutter, Katharina; Bellmann, Lydia; Cappellano, Giuseppe; Cadilha, Bruno L.; Kobold, Sebastian; Boon, Louis; Ortner, Daniela; Trajanoski, Zlatko; Chen, Suzie; de Gruijl, Tanja D.; Idoyaga, Juliana; Green, Douglas R. und Stoitzner, Patrizia
(2021):
Skin dendritic cells in melanoma are key for successful checkpoint blockade therapy.
In: Journal for Immunotherapy of Cancer, Bd. 9, Nr. 1, e000832
Lesch, Stefanie; Blumenberg, Viktoria; Stoiber, Stefan; Gottschlich, Adrian; Ogonek, Justyna; Cadilha, Bruno L.; Dantes, Zahra; Rataj, Felicitas; Dorman, Klara; Lutz, Johannes; Karches, Clara H.; Heise, Constanze; Kurzay, Mathias; Larimer, Benjamin M.; Grassmann, Simon; Rapp, Moritz; Nottebrock, Alessia; Kruger, Stephan; Tokarew, Nicholas; Metzger, Philipp; Hoerth, Christine; Benmebarek, Mohamed-Reda; Dhoqina, Dario; Grunmeier, Ruth; Seifert, Matthias; Oener, Arman; Umut, Oyku; Joaquina, Sandy; Vimeux, Lene; Tran, Thi; Hank, Thomas; Baba, Taisuke; Huynh, Duc; Megens, Remco T. A.; Janssen, Klaus-Peter; Jastroch, Martin; Lamp, Daniel; Ruehland, Svenja; Di Pilato, Mauro; Pruessmann, Jasper N.; Thomas, Moritz; Marr, Carsten; Ormanns, Steffen; Reischer, Anna; Hristov, Michael; Tartour, Eric; Donnadieu, Emmanuel; Rothenfusser, Simon; Duewell, Peter; Konig, Lars M.; Schnurr, Max; Subklewe, Marion; Liss, Andrew S.; Halama, Niels; Reichert, Maximilian; Mempel, Thorsten R.; Endres, Stefan und Kobold, Sebastian
(2021):
T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours.
In: Nature Biomedical Engineering, Bd. 5, Nr. 11
Di Pilato, Mauro; Kfuri-Rubens, Raphael; Pruessmann, Jasper N.; Ozga, Aleksandra J.; Messemaker, Marius; Cadilha, Bruno L.; Sivakumar, Ramya; Cianciaruso, Chiara; Warner, Ross D.; Marangoni, Francesco; Carrizosa, Esteban; Lesch, Stefanie; Billingsley, James; Perez-Ramos, Daniel; Zavala, Fidel; Rheinbay, Esther; Luster, Andrew D.; Gerner, Michael Y.; Kobold, Sebastian; Pittet, Mikael J. und Mempel, Thorsten R.
(2021):
CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment.
In: Cell, Bd. 184, Nr. 17, e22: S. 4512-4530
Cadilha, Bruno L.; Benmebarek, Mohamed-Reda; Dorman, Klara; Oner, Arman; Lorenzini, Theo; Obeck, Hannah; Vaenttinen, Mira; Di Pilato, Mauro; Pruessmann, Jasper N.; Stoiber, Stefan; Duc, Huynh; Maerkl, Florian; Seifert, Matthias; Manske, Katrin; Suarez-Gosalvez, Javier; Zeng, Yi; Lesch, Stefanie; Karches, Clara H.; Heise, Constanze; Gottschlich, Adrian; Thomas, Moritz; Marr, Carsten; Zhang, Jin; Pandey, Dharmendra; Feuchtinger, Tobias; Subklewe, Marion; Mempel, Thorsten R.; Endres, Stefan und Kobold, Sebastian
(2021):
Combined tumor-directed recruitment and protection from immune suppression enable CAR T cell efficacy in solid tumors.
In: Science Advances, Bd. 7, Nr. 24, eabi5781
Benmebarek, Mohamed-Reda; Cadilha, Bruno L.; Herrmann, Monika; Lesch, Stefanie; Schmitt, Saskia; Stoiber, Stefan; Darwich, Abbass; Augsberger, Christian; Brauchle, Bettina; Rohrbacher, Lisa; Oner, Arman; Seifert, Matthias; Schwerdtfeger, Melanie; Gottschlich, Adrian; Rataj, Felicitas; Fenn, Nadja C.; Klein, Christian ORCID: https://orcid.org/0000-0001-7594-7280; Subklewe, Marion; Endres, Stefan; Hopfner, Karl-Peter ORCID: https://orcid.org/0000-0002-4528-8357 und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2021):
A modular and controllable T cell therapy platform for acute myeloid leukemia.
In: Leukemia, Bd. 35: S. 2243-2257
[PDF, 5MB]
ORCID: https://orcid.org/0000-0001-7594-7280; Subklewe, Marion; Endres, Stefan; Hopfner, Karl-Peter ORCID: https://orcid.org/0000-0002-4528-8357 und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2021):
A modular and controllable T cell therapy platform for acute myeloid leukemia.
In: Leukemia, Bd. 35: S. 2243-2257
[PDF, 5MB]
2020
Lesch, Stefanie; Benmebarek, Mohamed-Reda; Cadilha, Bruno L.; Stoiber, Stefan; Subklewe, Marion; Endres, Stefan und Kobold, Sebastian
(2020):
Determinants of response and resistance to CAR T cell therapy.
In: Seminars in Cancer Biology, Bd. 65: S. 80-90
Kruger, Stephan F.; Cadilha, Bruno L.; Bergwelt‐Baildon, Michael von; Endres, Stefan und Kobold, Sebastian
(2020):
Challenges in Clinical Trial Design for T Cell‐Based Cancer Immunotherapy.
In: Clinical Pharmacology & Therapeutics, Bd. 107, Nr. 1: S. 47-49
[PDF, 236kB]
2019
Rataj, Felicitas; Jacobi, Severin J.; Stoiber, Stefan; Asang, Florian; Ogonek, Justyna; Tokarew, Nicholas; Cadilha, Bruno L.; van Puijenbroek, Erwin; Heise, Constanze; Duewell, Peter; Endres, Stefan; Klein, Christian und Kobold, Sebastian
(2019):
High-affinity CD16-polymorphism and Fc-engineered antibodies enable activity of CD16-chimeric antigen receptor-modified T cells for cancer therapy.
In: British Journal of Cancer, Bd. 120, Nr. 1: S. 79-87
Wiedemann, Gabriela M.; Aithal, Celina; Kraechan, Angelina; Heise, Constanze; Cadilha, Bruno L.; Zhang, Jin; Duewell, Peter; Ballotti, Robert; Endres, Stefan; Bertolotto, Corine und Kobold, Sebastian
(2019):
Microphthalmia-Associated Transcription Factor (MITF) Regulates Immune Cell Migration into Melanoma.
In: Translational Oncology, Bd. 12, Nr. 2: S. 350-360
Stoiber, Stefan; Cadilha, Bruno L.; Benmebarek, Mohamed-Reda; Lesch, Stefanie; Endres, Stefan und Kobold, Sebastian
(2019):
Limitations in the Design of Chimeric Antigen Receptors for Cancer Therapy.
In: Cells, Bd. 8, Nr. 5, 472
Krüger, Stephan; Ilmer, Matthias; Kobold, Sebastian; Cadilha, Bruno L.; Endres, Stefan; Ormanns, Steffen; Schuebbe, Gesa; Renz, Bernhard W.; D'Haese, Jan G.; Schloesser, Hans; Heinemann, Volker; Subklewe, Marion; Böck, Stefan; Werner, Jens und Bergwelt-Baildon, Michael von
(2019):
Advances in cancer immunotherapy 2019-latest trends.
In: Journal of Experimental & Clinical Cancer Research, Bd. 38, 268
Karches, Clara H.; Benmebarek, Mohamed-Reda; Schmidbauer, Moritz L.; Kurzay, Mathias; Klaus, Richard; Geiger, Martina; Rataj, Felicitas; Cadilha, Bruno L.; Lesch, Stefanie; Heise, Constanze; Murr, Ramona; vom Berg, Johannes; Jastroch, Martin; Lamp, Daniel; Ding, Jian; Duewell, Peter; Niederfellner, Gerhard; Sustmann, Claudio; Endres, Stefan; Klein, Christian und Kobold, Sebastian
(2019):
Bispecific Antibodies Enable Synthetic Agonistic Receptor-Transduced T Cells for Tumor Immunotherapy.
In: Clinical Cancer Research, Bd. 25, Nr. 19: S. 5890-5900
2018
Rataj, Felicitas; Kraus, Fabian B. T.; Chaloupka, Michael; Grassmann, Simon; Heise, Constanze; Cadilha, Bruno L.; Duewell, Peter; Endres, Stefan und Kobold, Sebastian
(2018):
PD1-CD28 Fusion Protein Enables CD4+ T Cell Help for Adoptive T Cell Therapy in Models of Pancreatic Cancer and Non-hodgkin Lymphoma.
In: Frontiers in Immunology, Bd. 9, 1955
[PDF, 600kB]