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Anzahl der Publikationen: 10
Zeitschriftenartikel
Arifi, Silvia; Zaienne, Daniel; Heering, Jan; Wein, Thomas; Zhubi, Rezart; Chaikuad, Apirat; Knapp, Stefan; Marschner, Julian A. und Merk, Daniel
(2022):
Fragment-based discovery of orphan nuclear receptor Nur77/NGFI-B ligands.
In: Bioorganic Chemistry, Bd. 129, 106164
Faudone, Giuseppe; Zhubi, Rezart; Celik, Fatih; Knapp, Stefan; Chaikuad, Apirat; Heering, Jan und Merk, Daniel
(2022):
Design of a Potent TLX Agonist by Rational Fragment Fusion.
In: Journal of Medicinal Chemistry, Bd. 65, Nr. 3: S. 2288-2296
Isigkeit, Laura; Chaikuad, Apirat und Merk, Daniel
(2022):
A Consensus Compound/Bioactivity Dataset for Data-Driven Drug Design and Chemogenomics.
In: Molecules, Bd. 27, Nr. 8, 2513
Heering, Jan; Jores, Nathalie; Kilu, Whitney; Schallmayer, Espen; Peelen, Evelyn; Muehler, Andreas; Kohlhof, Hella; Vitt, Daniel; Linhard, Verena; Gande, Santosh L.; Chaikuad, Apirat; Sreeramulu, Sridhar; Schwalbe, Harald und Merk, Daniel
(2022):
Mechanistic Impact of Different Ligand Scaffolds on FXR Modulation Suggests Avenues to Selective Modulators.
In: ACS Chemical Biology, Bd. 17, Nr. 11: S. 3159-3168
Adouvi, Gustave; Isigkeit, Laura; Lopez-Garcia, Ursula; Chaikuad, Apirat; Marschner, Julian A.; Schubert-Zsilavecz, Manfred und Merk, Daniel
(2022):
Rational Design of a New RXR Agonist Scaffold Enabling Single-Subtype Preference for RXR alpha, RXR beta, and RXR gamma.
In: Journal of Medicinal Chemistry, Bd. 66, Nr. 1: S. 333-344
Faudone, Giuseppe; Kilu, Whitney; Ni, Xiaomin; Chaikuad, Apirat; Sreeramulu, Sridhar; Heitel, Pascal; Schwalbe, Harald; Knapp, Stefan; Schubert-Zsilavecz, Manfred; Heering, Jan und Merk, Daniel
(2021):
The Transcriptional Repressor Orphan Nuclear Receptor TLX Is Responsive to Xanthines.
In: ACS Pharmacology & Translational Science, Bd. 4, Nr. 6: S. 1794-1807
Mueller, Susanne; Ackloo, Suzanne; Al Chawaf, Arij; Al-Lazikani, Bissan; Antolin, Albert; Baell, Jonathan B.; Beck, Hartmut; Beedie, Shaunna; Betz, Ulrich A. K.; Bezerra, Gustavo Arruda; Brennan, Paul E.; Brown, David; Brown, Peter J.; Bullock, Alex N.; Carter, Adrian J.; Chaikuad, Apirat; Chaineau, Mathilde; Ciulli, Alessio; Collins, Ian; Dreher, Jan; Drewry, David; Edfeldt, Kristina; Edwards, Aled M.; Egner, Ursula; Frye, Stephen V.; Fuchs, Stephen M.; Hall, Matthew D.; Hartung, Ingo V.; Hillisch, Alexander; Hitchcock, Stephen H.; Homan, Evert; Kannan, Natarajan; Kiefer, James R.; Knapp, Stefan; Kostic, Milka; Kubicek, Stefan; Leach, Andrew R.; Lindemann, Sven; Marsden, Brian D.; Matsui, Hisanori; Meier, Jordan L.; Merk, Daniel; Michel, Maurice; Morgan, Maxwell R.; Mueller-Fahrnow, Anke; Owen, Dafydd R.; Perry, Benjamin G.; Rosenberg, Saul H.; Saikatendu, Kumar Singh; Schapira, Matthieu; Scholten, Cora; Sharma, Sujata; Simeonov, Anton; Sundstrom, Michael; Superti-Furga, Giulio; Todd, Matthew H.; Tredup, Claudia; Vedadi, Masoud; Delft, Frank von; Willson, Timothy M.; Winter, Georg E.; Workman, Paul und Arrowsmith, Cheryl H.
(2021):
Target 2035-update on the quest for a probe for every protein.
In: Rsc Medicinal Chemistry, Bd. 13, Nr. 1: S. 13-21
Reynders, Martin; Chaikuad, Apirat; Berger, Benedict-Tilman; Bauer, Katharina; Koch, Pierre; Laufer, Stefan; Knapp, Stefan und Trauner, Dirk
(2021):
Controlling the Covalent Reactivity of a Kinase Inhibitor with Light.
In: Angewandte Chemie-International Edition, Bd. 60, Nr. 37: S. 20178-20183
Schroeder, Martin; Bullock, Alex N.; Fedorov, Oleg; Bracher, Franz; Chaikuad, Apirat und Knapp, Stefan
(2020):
DFG-1 Residue Controls Inhibitor Binding Mode and Affinity, Providing a Basis for Rational Design of Kinase Inhibitor Selectivity.
In: Journal of Medicinal Chemistry, Bd. 63, Nr. 18: S. 10224-10234
Wurzlbauer, Anne; Rueben, Katharina; Guerdal, Ece; Chaikuad, Apirat; Knapp, Stefan; Sippl, Wolfgang; Becker, Walter und Bracher, Franz
(2020):
How to Separate Kinase Inhibition from Undesired Monoamine Oxidase A Inhibition-The Development of the DYRK1A Inhibitor AnnH75 from the Alkaloid Harmine.
In: Molecules, Bd. 25, Nr. 24, 5962