Anzahl der Publikationen: 24
2022
Wang, Jingyuan; Xiao, Yi; Loupakis, Fotios; Stintzing, Sebastian; Yang, Yan; Arai, Hiroyuki; Battaglin, Francesca; Kawanishi, Natsuko; Jayachandran, Priya; Soni, Shivani; Zhang, Wu; Mancao, Christoph; Cremolini, Chiara; Liu, Tianshu; Heinemann, Volker; Falcone, Alfredo; Shen, Lin; Millstein, Joshua und Lenz, Heinz-Josef
(2022):
Genetic variants involved in the cGAS-STING pathway predict outcome in patients with metastatic colorectal cancer: Data from FIRE-3 and TRIBE trials.
In: European Journal of Cancer, Bd. 172: S. 22-30
2021
Yin, Jun; Cohen, Romain; Jin, Zhaohui; Liu, Heshan; Pederson, Levi; Adams, Richard; Grothey, Axel; Maughan, Timothy S.; Venook, Alan; Cutsem, Eric van; Punt, Cornelis; Koopman, Miriam; Falcone, Alfredo; Tebbutt, Niall C.; Seymour, Matthew T.; Bokemeyer, Carsten; Rubio, Eduardo Diaz; Kaplan, Richard; Heinemann, Volker; Chibaudel, Benoist; Yoshino, Takayuki; Zalcberg, John; Andre, Thierry; Gramont, Aimery de; Shi, Qian und Lenz, Heinz-Josef
(2021):
Prognostic and Predictive Impact of Primary Tumor Sidedness for Previously Untreated Advanced Colorectal Cancer.
In: Jnci-Journal of the National Cancer Institute, Bd. 113, Nr. 12: S. 1705-1713
Naseem, Madiha; Cao, Shu; Yang, Dongyun; Millstein, Joshua; Puccini, Alberto; Loupakis, Fotios; Stintzing, Sebastian; Cremolini, Chiara; Tokunaga, Ryuma; Battaglin, Francesca; Soni, Shivani; Berger, Martin D.; Barzi, Afsaneh; Zhang, Wu; Falcone, Alfredo; Heinemann, Volker und Lenz, Heinz-Josef
(2021):
Random survival forests identify pathways with polymorphisms predictive of survival in KRAS mutant and KRAS wild-type metastatic colorectal cancer patients.
In: Scientific Reports, Bd. 11, Nr. 1, 12191
Cohen, Romain; Liu, Heshan; Fiskum, Jack; Adams, Richard; Chibaudel, Benoist; Maughan, Timothy S.; Cutsem, Eric van; Venook, Alan; Douillard, Jean-Yves; Heinemann, Volker; Punt, Cornelis Ja; Falcone, Alfredo; Bokemeyer, Carsten; Kaplan, Richard; Lenz, Heinz-Josef; Koopman, Miriam; Yoshino, Takayuki; Zalcberg, John; Grothey, Alex; Gramont, Aimery de; Shi, Qian und Andre, Thierry
(2021):
BRAF(V600E) Mutation in First-Line Metastatic Colorectal Cancer: An Analysis of Individual Patient Data From the ARCAD Database.
In: Jnci-Journal of the National Cancer Institute, Bd. 113, Nr. 10, djab042: S. 1386-1395
Arai, Hiroyuki; Millstein, Joshua; Loupakis, Fotios; Stintzing, Sebastian; Wang, Jingyuan; Battaglin, Francesca; Kawanishi, Natsuko; Jayachandran, Priya; Soni, Shivani; Zhang, Wu; Mumenthaler, Shannon M.; Cremolini, Chiara; Heinemann, Volker; Falcone, Alfredo und Lenz, Heinz-Josef
(2021):
Germ line polymorphisms of genes involved in pluripotency transcription factors predict efficacy of cetuximab in metastatic colorectal cancer.
In: European Journal of Cancer, Bd. 150: S. 133-142
Arai, Hiroyuki; Cao, Shu; Battaglin, Francesca; Wang, Jingyuan; Kawanishi, Natsuko; Tokunaga, Ryuma; Loupakis, Fotios; Stintzing, Sebastian; Soni, Shivani; Zhang, Wu; Mancao, Christoph; Salhia, Bodour; Mumenthaler, Shannon M.; Cremolini, Chiara; Heinemann, Volker; Falcone, Alfredo; Millstein, Joshua und Lenz, Heinz-Josef
(2021):
RNA-Binding Protein Polymorphisms as Novel Biomarkers to Predict Outcomes of Metastatic Colorectal Cancer: A Meta-analysis from TRIBE, FIRE-3, and MAVERICC.
In: Molecular Cancer Therapeutics, Bd. 20, Nr. 6: S. 1153-1160
2020
Volz, Nico B.; Hanna, Diana L.; Stintzing, Sebastian; Zhang, Wu; Yang, Dongyun; Cao, Shu; Ning, Yan; Matsusaka, Satoshi; Sunakawa, Yu; Berger, Martin D.; Cremolini, Chiara; Loupakis, Fotios; Falcone, Alfredo und Lenz, Heinz-Josef
(2020):
Polymorphisms within Immune Regulatory Pathways Predict Cetuximab Efficacy and Survival in Metastatic Colorectal Cancer Patients.
In: Cancers, Bd. 12, Nr. 10, 2947
Berger, Martin D.; Ning, Yan; Stintzing, Sebastian; Heinemann, Volker; Cao, Shu; Zhang, Wu; Yang, Dongyun; Miyamoto, Yuji; Suenaga, Mitsukuni; Schirripa, Marta; Hanna, Diana L.; Soni, Shivani; Puccini, Alberto; Tokunaga, Ryuma; Naseem, Madiha; Battaglin, Francesca; Cremolini, Chiara; Falcone, Alfredo; Loupakis, Fotios und Lenz, Heinz-Josef
(2020):
A polymorphism within the R-spondin 2 gene predicts outcome in metastatic colorectal cancer patients treated with FOLFIRI/bevacizumab: data from FIRE-3 and TRIBE trials.
In: European Journal of Cancer, Bd. 131: S. 89-97
2019
Puccini, Alberto; Loupakis, Fotios; Stintzing, Sebastian; Cao, Shu; Battaglin, Francesca; Togunaka, Ryuma; Naseem, Madiha; Berger, Martin D.; Soni, Shivani; Zhang, Wu; Mancao, Christoph; Salhia, Bodour; Mumenthaler, Shannon M.; Weisenberger, Daniel J.; Liang, Gangning; Cremolini, Chiara; Heinemann, Volker; Falcone, Alfredo; Millstein, Joshua und Lenz, Heinz-Josef
(2019):
Impact of polymorphisms within genes involved in regulating DNA methylation in patients with metastatic colorectal cancer enrolled in three independent, randomised, open-label clinical trials: a meta-analysis from TRIBE, MAVERICC and FIRE-3.
In: European Journal of Cancer, Bd. 111: S. 138-147
Tokunaga, Ryuma; Cao, Shu; Naseem, Madiha; Lo, Jae Ho; Battaglin, Francesca; Puccini, Alberto; Berger, Martin D.; Soni, Shivani; Millstein, Joshua; Zhang, Wu; Stintzing, Sebastian; Loupakis, Fotios; Cremolini, Chiara; Heinemann, Volker; Falcone, Alfredo und Lenz, Heinz-Josef
(2019):
Prognostic Effect of Adenosine-related Genetic Variants in Metastatic Colorectal Cancer Treated With Bevacizumab-based Chemotherapy.
In: Clinical Colorectal Cancer, Bd. 18, Nr. 1, E8-E19
Burzykowski, Tomasz; Coart, Elisabeth; Saad, Everardo D.; Shi, Qian; Sommeijer, Dirkje W.; Bokemeyer, Carsten; Diaz-Rubio, Eduardo; Douillard, Jean-Yves; Falcone, Alfredo; Fuchs, Charles S.; Goldberg, Richard M.; Hecht, J. Randolph; Hoff, Paulo M.; Hurwitz, Herbert; Kabbinavar, Fairooz F.; Koopman, Miriam; Maughan, Timothy S.; Punt, Cornelis J. A.; Saltz, Leonard; Schmoll, Hans-Joachim; Seymour, Matthew T.; Tebbutt, Niall C.; Tournigand, Christophe; Van Cutsem, Eric; de Gramont, Aimery; Zalcberg, John R.; Buyse, Marc; Adam, Rene; Adams, Richard; Ajani, Jaffer; Allegra, Carmen Joseph; Andre, Thierry; Arnold, Dirk; Bachet, Jean-Baptiste; Benson, Al Bowen; Berlin, Jordan; Bleiberg, Harry; Bodoky, Gyorgy; Buyse, Marc; Chibaudel, Benoist; Diaz-Rubio, Eduardo; Douillard, Jean-Yves; Ellis, Lee; Eng, Cathy; Falcone, Alfredo; Franko, Jan; Fuchs, Charles S.; Fujii, Masashi; Giantonio, Bruce J.; Goldberg, Richard M.; de Gramont, Aimery; Grothey, Axel; Haller, Daniel; Hamilton, Stan R.; Hausner, Petr F.; Hecht, J. Randolph; Heinemann, Volker; Herrera, Alain; Hochster, Howard S.; Hoff, Paulo M.; Jonker, Derek J.; Kaplan, Rick; Koeberle, Dieter; Kopetz, Scott; Labianca, Roberto F.; Larsen, Annette K.; Lenz, Heinz-Joseph; Lieu, Christopher; Louvet, Christophe; Loupakis, Fotios; Marshall, John; Maughan, Timothy S.; Mayer, Robert J.; Meropol, Neal J.; Mitchell, Edith P.; O'Connell, Michael J.; Peeters, Marc; Porschen, Rainer; Price, Timothy; Punt, Cornelis J. A.; Salem, Mohamed E.; Saltz, Leonard; Schilsky, Richard; Schmoll, Hans-Joachim; Seymour, Matthew T.; Shmueli, Einat Shacham; Shi, Qian; Sobrero, Alberto; Souglakos, John; Tabernero, Josep; Taieb, Julien; Tebbutt, Niall C.; Tejpar, Sabine; Tempero, Margaret; Tournigand, Christophe; Tsuji, Yasushi; Van Cutsem, Eric; Venook, Alan P.; Yoshino, Takayuki; Weinberg, Benjamin A.; Wolmark, Norman und Zalcberg, John R.
(2019):
Evaluation of Continuous Tumor-Size-Based End Points as Surrogates for Overall Survival in Randomized Clinical Trials in Metastatic Colorectal Cancer.
In: Jama Network Open, Bd. 2, Nr. 9, e1911750
2018
Schirripa, Marta; Zhang, Wu; Yang, Dongyun; Cao, Shu; Okazaki, Satoshi; Loupakis, Fotios; Berger, Martin D.; Ning, Yan; Miyamoto, Yuji; Suenaga, Mitsukuni; Alberti, Giulia; West, Jordan D.; Lonardi, Sara; Khoukaz, Taline; Bergamo, Francesca; Battaglin, Francesca; Antoniotti, Carlotta; Falcone, Alfredo; Stintzing, Sebastian; Heinemann, Volker und Lenz, Heinz-Josef
(2018):
NOS2 polymorphisms in prediction of benefit from first-line chemotherapy in metastatic colorectal cancer patients.
In: PLOS One
13(3), e0193640
[PDF, 2MB]
Berger, Martin D.; Stintzing, Sebastian; Heinemann, Volker; Cao, Shu; Yang, Dongyun; Sunakawa, Yu; Matsusaka, Satoshi; Ning, Yan; Okazaki, Satoshi; Miyamoto, Yuji; Suenaga, Mitsukuni; Schirripa, Marta; Hanna, Diana L.; Soni, Shivani; Puccini, Alberto; Zhang, Wu; Cremolini, Chiara; Falcone, Alfredo; Loupakis, Fotios und Lenz, Heinz-Josef
(2018):
A Polymorphism within the Vitamin D Transporter Gene Predicts Outcome in Metastatic Colorectal Cancer Patients Treated with FOLFIRI/Bevacizumab or FOLFIRI/Cetuximab.
In: Clinical Cancer Research, Bd. 24, Nr. 4: S. 784-793
Goey, Kaitlyn K. H.; Sorbye, Halfdan; Glimelius, Bengt; Adams, Richard A.; Andre, Thierry; Arnold, Dirk; Berlin, Jordan D.; Bodoky, Gyorgy; de Gramont, Aimery; Diaz-Rubio, Eduardo; Eng, Cathy; Falcone, Alfredo; Grothey, Axel; Heineman, Volker; Hochster, Howard S.; Kaplan, Richard S.; Kopetz, Scott; Labianca, Roberto; Lieu, Christopher H.; Meropol, Neal J.; Price, Timothy J.; Schilsky, Richard L.; Schmoll, Hans-Joachim; Shacham-Shmueli, Einat; Shi, Qian; Sobrero, Alberto F.; Souglakos, John; Cutsem, Eric van; Zalcberg, John; Oijen, Martijn G. H. van; Punt, Cornelis J. A. und Koopman, Miriam
(2018):
Consensus statement on essential patient characteristics in systemic treatment trials for metastatic colorectal cancer: Supported by the ARCAD Group.
In: European Journal of Cancer, Bd. 100: S. 35-45
Suenaga, Mitsukuni; Schirripa, Marta; Cao, Shu; Zhang, Wu; Yang, Dongyun; Cremolini, Chiara; Lonardi, Sara; Bergamo, Francesca; Ning, Yang; Yamamoto, Noriko; Okazaki, Satoshi; Berger, Martin D.; Miyamoto, Yuji; Gopez, Roel; Barzi, Afsaneh; Yamaguchi, Toshiharu; Stintzing, Sebastian; Heinemann, Volker; Loupakis, Fotios; Falcone, Alfredo und Lenz, Heinz-Josef
(2018):
Potential role of PIN1 genotypes in predicting benefit from oxaliplatin-based and irinotecan-based treatment in patients with metastatic colorectal cancer.
In: Pharmacogenomics Journal, Bd. 18, Nr. 5: S. 623-632
Salem, Mohamed E.; Yin, Jun; Weinberg, Benjamin A.; Renfro, Lindsay A.; Pederson, Levi D.; Maughan, Timothy S.; Adams, Richard A.; Cutsem, Eric van; Falcone, Alfredo; Tebbutt, Niall C.; Seymour, Matthew T.; Diaz-Rubio, Eduardo; Aranda, Enrique; Bokemeyer, Carsten; Heinemann, Volker; Wasan, Harpreet; Gramont, Aimery de; Grothey, Axel; Shi, Qian; Sargent, Daniel J. und Marshall, John L.
(2018):
Clinicopathological differences and survival outcomes with first-line therapy in patients with left-sided colon cancer and rectal cancer: Pooled analysis of 2879 patients from AGITG (MAX), COIN, FOCUS2, OPUS, CRYSTAL and COIN-B trials in the ARCAD database.
In: European Journal of Cancer, Bd. 103: S. 205-213
2017
Renfro, Lindsay A.; Goldberg, Richard M.; Grothey, Axel; Sobrero, Alberto; Adams, Richard; Seymour, Matthew T.; Heinemann, Volker; Schmoll, Hans-Joachim; Douillard, Jean-Yves; Hurwitz, Herbert; Fuchs, Charles S.; Diaz-Rubio, Eduardo; Porschen, Rainer; Tournigand, Christophe; Chibaudel, Benoist; Hoff, Paulo M.; Kabbinavar, Fairooz F.; Falcone, Alfredo; Tebbutt, Niall C.; Punt, Cornelis J. A.; Hecht, J. Randolph; Souglakos, John; Bokemeyer, Carsten; Cutsem, Eric van; Saltz, Leonard; Gramont, Aimery de und Sargent, Daniel J.
(2017):
Clinical Calculator for Early Mortality in Metastatic Colorectal Cancer: An Analysis of Patients From 28 Clinical Trials in the Aide et Recherche en Cancerologie Digestive Database.
In: Journal of Clinical Oncology, Bd. 35, Nr. 17: S. 1929-1937
Schirripa, Marta; Zhang, Wu; Heinemann, Volker; Cao, Shu; Okazaki, Satoshi; Yang, Dongyun; Loupakis, Fotios; Berger, Martin D.; Ning, Yan; Miyamoto, Yuji; Suenaga, Mitsukuni; Gopez, Roel F.; West, Jordan D.; Hanna, Diana; Barzi, Afsaneh; Falcone, Alfredo; Stintzing, Sebastian und Lenz, Heinz-Josef
(2017):
Single nucleotide polymorphisms in the IGF-IRS pathway are associated with outcome in mCRC patients enrolled in the FIRE-3 trial.
In: International Journal of Cancer, Bd. 141, Nr. 2: S. 383-392
Berger, Martin D.; Yamauchi, Shinichi; Cao, Shu; Hanna, Diana L.; Sunakawa, Yu; Schirripa, Marta; Matsusaka, Satoshi; Yang, Dongyun; Groshen, Susan; Zhang, Wu; Ning, Yan; Okazaki, Satoshi; Miyamoto, Yuji; Suenaga, Mitsukuni; Lonardi, Sara; Cremolini, Chiara; Falcone, Alfredo; Heinemann, Volker; Loupakis, Fotios; Stintzing, Sebastian und Lenz, Heinz-Josef
(2017):
Autophagy-related polymorphisms predict hypertension in patients with metastatic colorectal cancer treated with FOLFIRI and bevacizumab: Results from TRIBE and FIRE-3 trials.
In: European Journal of Cancer, Bd. 77: S. 13-20
2016
Okazaki, Satoshi; Loupakis, Fotios; Stintzing, Sebastian; Cao, Shu; Zhang, Wu; Yang, Dongyun; Ning, Yan; Sunakawa, Yu; Stremitzer, Stefan; Matsusaka, Satoshi; Berger, Martin D.; Parekh, Anish; West, Jordan D.; Miyamoto, Yuji; Suenaga, Mitsukuni; Schirripa, Marta; Cremolini, Chiara; Falcone, Alfredo; Heinemann, Volker; DePaolo, R. William und Lenz, Heinz-Josef
(2016):
Clinical Significance of TLR1 I602S Polymorphism for Patients with Metastatic Colorectal Cancer Treated with FOLFIRI plus Bevacizumab.
In: Molecular Cancer therapeutics, Bd. 15, Nr. 7: S. 1740-1745
Franko, Jan; Shi, Qian; Meyers, Jeffrey P.; Maughan, Timothy S.; Adams, Richard A.; Seymour, Matthew T.; Saltz, Leonard; Punt, Cornelis J. A.; Koopman, Miriam; Tournigand, Christophe; Tebbutt, Niall C.; Diaz-Rubio, Eduardo; Souglakos, John; Falcone, Alfredo; Chibaudel, Benoist; Heinemann, Volker; Moen, Joseph; Gramont, Aimery de; Sargent, Daniel J. und Grothey, Axel
(2016):
Prognosis of patients with peritoneal metastatic colorectal cancer given systemic therapy: an analysis of individual patient data from prospective randomised trials from the Analysis and Research in Cancers of the Digestive System (ARCAD) database.
In: Lancet Oncology, Bd. 17, Nr. 12: S. 1709-1719
Koopman, Miriam; Shi, Qian; Goey, Kaitlyn K. H.; Green, Erin; Heinemann, Volker; Diaz-Rubio, Eduardo; Aranda, Enrique; Falcone, Alfredo; Gramont, Aimery de; Sargent, Daniel J. und Punt, Cornelis J. A.
(2016):
Prognostic value of primary tumor resection in synchronous metastatic colorectal cancer (mCRC): Individual patient data (IPD) analysis of first-line randomized trials from the ARCAD database.
In: Journal of Clinical Oncology, Bd. 34, Nr. 4
Franko, Jan; Shi, Qian; Meyers, Jeffrey P.; Heinemann, Volker; Falcone, Alfredo; Tebbutt, Niall C.; Maughan, Tim; Seymour, Matthew; Saltz, Leonard; Tournigand, Christophe; Diaz-Rubio, Eduardo; Sougklakos, Ioannis; Chibaudel, Benoist; Moen, Joseph; Gramont, Aimery de; Adams, Richard A.; Sargent, Daniel J. und Grothey, Axel
(2016):
Prognostic value of isolated peritoneal versus other metastatic sites in colorectal cancer (CRC) patients treated by systemic chemotherapy: Findings from 9,265 pts in the ARCAD database.
In: Journal of Clinical Oncology, Bd. 34, Nr. 4
Renfro, Lindsay A.; Loupakis, Fotios; Adams, Richard A.; Seymour, Matthew T.; Heinemann, Volker; Schmoll, Hans-Joachim; Douillard, Jean-Yves; Hurwitz, Herbert; Fuchs, Charles S.; Diaz-Rubio, Eduardo; Porschen, Rainer; Tournigand, Christophe; Chibaudel, Benoist; Falcone, Alfredo; Tebbutt, Niall C.; Punt, Cornelis J. A.; Hecht, J. Randolph; Bokemeyer, Carsten; Cutsem, Eric van; Goldberg, Richard M.; Saltz, Leonard B.; Gramont, Aimery de; Sargent, Daniel J. und Lenz, Heinz-Josef
(2016):
Body Mass Index Is Prognostic in Metastatic Colorectal Cancer: Pooled Analysis of Patients From First-Line Clinical Trials in the ARCAD Database.
In: Journal of Clinical Oncology, Bd. 34, Nr. 2: S. 144-150
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