Anzahl der Publikationen: 84
Zeitschriftenartikel
Levin, Johannes ORCID: https://orcid.org/0000-0001-5092-4306; Baiardi, Simone; Quadalti, Corinne; Rossi, Marcello; Mammana, Angela; Vöglein, Jonathan; Bernhardt, Alexander; Perrin, Richard J.; Jucker, Mathias; Preische, Oliver; Hofmann, Anna; Höglinger, Günter U.; Cairns, Nigel J.; Franklin, Erin E.; Chrem, Patricio; Cruchaga, Carlos; Berman, Sarah B.; Chhatwal, Jasmeer P.; Daniels, Alisha; Day, Gregory S.; Ryan, Natalie S.; Goate, Alison M.; Gordon, Brian A.; Huey, Edward D.; Ibanez, Laura; Karch, Celeste M.; Lee, Jae‐Hong; Llibre‐Guerra, Jorge; Lopera, Francisco; Masters, Colin L.; Morris, John C.; Noble, James M.; Renton, Alan E.; Roh, Jee Hoon; Frosch, Matthew P.; Keene, C. Dirk; McLean, Catriona; Sanchez‐Valle, Raquel; Schofield, Peter R.; Supnet‐Bell, Charlene; Xiong, Chengjie; Giese, Armin; Hansson, Oskar; Bateman, Randall J.; McDade, Eric und Parchi, Piero ORCID: https://orcid.org/0000-0002-9444-9524
(2024):
α‐Synuclein seed amplification assay detects Lewy body co‐pathology in autosomal dominant Alzheimer's disease late in the disease course and dependent on Lewy pathology burden.
In: Alzheimer's & Dementia [Forthcoming]
[PDF, 1MB]
Dening, Yanina; Straßl, Theresa; Ruf, Viktoria; Dirscherl, Petra; Chovsepian, Alexandra; Stievenard, Alicia; Khairnar, Amit; Schmidt, Felix; Giesert, Florian; Herms, Jochen; Levin, Johannes; Dieterich, Marianne; Falkai, Peter; Weisenhorn, Daniela Vogt; Wurst, Wolfgang; Giese, Armin und Pan-Montojo, Francisco
(19. Dezember 2022):
Toxicity of extracellular alpha-synuclein is independent of intracellular alpha-synuclein.
In: Scientific Reports, Bd. 12, Nr. 1
[PDF, 9MB]
Franzmeier, Nicolai; Brendel, Matthias; Beyer, Leonie; Slemann, Luna; Kovacs, Gabor G.; Arzberger, Thomas; Kurz, Carolin; Respondek, Gesine; Lukic, Milica J.; Biel, Davina; Rubinski, Anna; Frontzkowski, Lukas; Hummel, Selina; Müller, Andre; Finze, Anika; Palleis, Carla; Joseph, Emanuel; Weidinger, Endy; Katzdobler, Sabrina; Song, Mengmeng; Biechele, Gloria; Kern, Maike; Scheifele, Maximilian; Rauchmann, Boris-Stephan; Perneczky, Robert; Rullman, Michael; Patt, Marianne; Schildan, Andreas; Barthel, Henryk; Sabri, Osama; Rumpf, Jost J.; Schroeter, Matthias L.; Classen, Joseph; Villemagne, Victor; Seibyl, John; Stephens, Andrew W.; Lee, Edward B.; Coughlin, David G.; Giese, Armin; Grossman, Murray; McMillan, Corey T.; Gelpi, Ellen; Molina-Porcel, Laura; Compta, Yaroslau; van Swieten, John C.; Laat, Laura Donker; Troakes, Claire; Al-Sarraj, Safa; Robinson, John L.; Xie, Sharon X.; Irwin, David J.; Roeber, Sigrun; Herms, Jochen; Simons, Mikael; Bartenstein, Peter; Lee, Virginia M.; Trojanowski, John Q.; Levin, Johannes; Höglinger, Günter und Ewers, Michael
(15. März 2022):
Tau deposition patterns are associated with functional connectivity in primary tauopathies.
In: Nature Communications, Bd. 13
[PDF, 7MB]
Lukic, Milica Jecmenica; Respondek, Gesine; Kurz, Carolin; Compta, Yaroslau; Gelpi, Ellen; Ferguson, Leslie W.; Rajput, Alex; Troakes, Claire; Swieten, John C. van; Giese, Armin; Roeber, Sigrun; Herms, Jochen; Arzberger, Thomas und Höglinger, Günter
(2022):
Long-Duration Progressive Supranuclear Palsy: Clinical Course and Pathological Underpinnings.
In: Annals of Neurology, Bd. 92, Nr. 4: S. 637-649
[PDF, 2MB]
Halbgebauer, Steffen; Steinacker, Petra; Riedel, Daniel; Oeckl, Patrick; Anderl-Straub, Sarah; Lombardi, Jolina; Arnim, Christine A. F. von; Nagl, Magdalena; Giese, Armin; Ludolph, Albert C. und Otto, Markus
(2022):
Visinin-like protein 1 levels in blood and CSF as emerging markers for Alzheimer's and other neurodegenerative diseases.
In: Alzheimer'S Research & Therapy, Bd. 14, Nr. 1, 175
Antonschmidt, Leif; Matthes, Dirk; Dervisoglu, Riza; Frieg, Benedikt; Dienemann, Christian; Leonov, Andrei; Nimerovsky, Evgeny; Sant, Vrinda; Ryazanov, Sergey; Giese, Armin; Schroeder, Gunnar F.; Becker, Stefan; de Groot, Bert L.; Griesinger, Christian und Andreas, Loren B.
(2022):
The clinical drug candidate anle138b binds in a cavity of lipidic alpha-synuclein fibrils.
In: Nature Communications, Bd. 13, Nr. 1, 5385
Halbgebauer, Steffen; Abu-Rumeileh, Samir; Oeckl, Patrick; Steinacker, Petra; Roselli, Francesco; Wiesner, Diana; Mammana, Angela; Beekes, Michael; Kortazar-Zubizarreta, Izaro; Perez de Nanclares, Guiomar; Capellari, Sabina; Giese, Armin; Castilla, Joaquin; Ludolph, Albert C.; Zakova, Dana; Parchi, Piero und Otto, Markus
(2022):
Blood beta-Synuclein and Neurofilament Light Chain During the Course of Prion Disease.
In: Neurology, Bd. 98, Nr. 14, E1434-E1445
Levin, Johannes; Sing, Nand; Melbourne, Sue; Morgan, Amber; Mariner, Carla; Spillantini, Maria Grazia; Wegrzynowicz, Michal; Dalley, Jeffrey W.; Langer, Simon; Ryazanov, Sergey; Leonov, Andrei; Griesinger, Christian; Schmidt, Felix; Weckbecker, Daniel; Prager, Kai; Matthias, Torsten und Giese, Armin
(2022):
Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised, double-blind placebo-controlled phase 1a trial.
In: eBioMedicine, Bd. 80, 104021
[PDF, 612kB]
Halbgebauer, Steffen; Steinacker, Petra ORCID: https://orcid.org/0000-0001-6697-6522; Hengge, Sophie; Oeckl, Patrick ORCID: https://orcid.org/0000-0002-7652-7023; Abu Rumeileh, Samir ORCID: https://orcid.org/0000-0003-0631-8506; Anderl-Straub, Sarah; Lombardi, Jolina; Arnim, Christine A. F. von; Giese, Armin; Ludolph, Albert C. und Otto, Markus ORCID: https://orcid.org/0000-0003-4273-4267
(2022):
CSF levels of SNAP-25 are increased early in Creutzfeldt-Jakob and Alzheimer’s disease.
In: Journal of Neurology, Neurosurgery & Psychiatry, Bd. 93, Nr. 10: S. 1059-1065
Smith, Rebecca G.; Pishva, Ehsan; Shireby, Gemma; Smith, Adam R.; Roubroeks, Janou A. Y.; Hannon, Eilis; Wheildon, Gregory; Mastroeni, Diego; Gasparoni, Gilles; Riemenschneider, Matthias; Giese, Armin; Sharp, Andrew J.; Schalkwyk, Leonard; Haroutunian, Vahram; Viechtbauer, Wolfgang; Hove, Daniel L. A. van den; Weedon, Michael; Brokaw, Danielle; Francis, Paul T.; Thomas, Alan J.; Love, Seth; Morgan, Kevin; Walter, Joern; Coleman, Paul D.; Bennett, David A.; Jager, Philip L. de; Mill, Jonathan und Lunnon, Katie
(2021):
A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex.
In: Nature Communications, Bd. 12, Nr. 1, 3517
Siller, Sebastian; Lauseker, Michael; Karschnia, Philipp; Niyazi, Maximilian; Eigenbrod, Sabina; Giese, Armin und Tonn, Joerg-Christian
(2021):
The number of methylated CpG sites within the MGMT promoter region linearly correlates with outcome in glioblastoma receiving alkylating agents.
In: Acta neuropathologica communications, Bd. 9, Nr. 1: S. 35
[PDF, 1MB]
Siller, Sebastian; Lauseker, Michael; Karschnia, Philipp; Niyazi, Maximilian; Eigenbrod, Sabina; Giese, Armin und Tonn, Joerg-Christian
(2021):
The number of methylated CpG sites within the MGMT promoter region linearly correlates with outcome in glioblastoma receiving alkylating agents.
In: Acta Neuropathologica Communications, Bd. 9, Nr. 35
[PDF, 1MB]
Baiardi, Simone; Rossi, Marcello; Mammana, Angela; Appleby, Brian S.; Barria, Marcelo A.; Cali, Ignazio; Gambetti, Pierluigi; Gelpi, Ellen; Giese, Armin; Ghetti, Bernardino; Herms, Jochen; Ladogana, Anna; Mikol, Jacqueline; Pal, Suvankar; Ritchie, Diane L.; Ruf, Viktoria; Windl, Otto; Capellari, Sabina und Parchi, Piero
(2021):
Phenotypic diversity of genetic Creutzfeldt-Jakob disease: a histo-molecular-based classification.
In: Acta Neuropathologica, Bd. 142, Nr. 4: S. 707-728
Romano, Mariele; Bravin, Alberto; Mittone, Alberto; Eckhardt, Alicia; Barbone, Giacomo E.; Sancey, Lucie; Dinkel, Julien; Bartzsch, Stefan; Ricke, Jens; Alunni-Fabbroni, Marianna; Hirner-Eppeneder, Heidrun; Karpov, Dmitry; Giannini, Cinzia; Bunk, Oliver; Bouchet, Audrey; Ruf, Viktoria; Giese, Armin und Coan, Paola
(2021):
A Multi-Scale and Multi-Technique Approach for the Characterization of the Effects of Spatially Fractionated X-ray Radiation Therapies in a Preclinical Model.
In: Cancers, Bd. 13, Nr. 19, 4953
Schuller, Ulrich; Iglauer, Peter; Dorostkar, Mario M.; Mawrin, Christian; Herms, Jochen; Giese, Armin; Glatzel, Markus und Neumann, Julia E.
(2021):
Mutations within FGFR1 are associated with superior outcome in a series of 83 diffuse midline gliomas with H3F3A K27M mutations.
In: Acta Neuropathologica, Bd. 141, Nr. 2: S. 323-325
Siller, Sebastian; Lauseker, Michael; Karschnia, Philipp; Niyazi, Maximilian; Eigenbrod, Sabina; Giese, Armin und Tonn, Jörg-Christian
(2021):
The number of methylated CpG sites within the MGMT promoter region linearly correlates with outcome in glioblastoma receiving alkylating agents.
In: Acta Neuropathologica Communications, Bd. 9, Nr. 1, 35
Vöglein, Jonathan; Kostova, Irena; Arzberger, Thomas; Noachtar, Soheyl; Dieterich, Marianne; Herms, Jochen; Schmitz, Peer; Ruf, Viktoria; Windl, Otto; Roeber, Sigrun; Simons, Mikael; Höglinger, Günter U.; Danek, Adrian; Giese, Armin und Levin, Johannes
(2021):
Seizure prevalence in neurodegenerative diseases-a study of autopsy proven cases.
In: European Journal of Neurology, Bd. 29, Nr. 1: S. 12-18
[PDF, 296kB]
Vöglein, Jonathan; Kostova, Irena; Arzberger, Thomas; Roeber, Sigrun; Schmitz, Peer; Simons, Mikael; Ruf, Viktoria; Windl, Otto; Herms, Jochen; Dieterich, Marianne; Danek, Adrian; Höglinger, Günter U.; Giese, Armin und Levin, Johannes
(2021):
First symptom guides diagnosis and prognosis in neurodegenerative diseases-a retrospective study of autopsy proven cases.
In: European Journal of Neurology, Bd. 28, Nr. 6: S. 1801-1811
[PDF, 375kB]
Ruf, Viktoria C.; Shi, Song; Schmidt, Felix; Weckbecker, Daniel; Nübling, Georg S.; Ködel, Uwe; Mollenhauer, Brit und Giese, Armin
(2020):
Potential sources of interference with the highly sensitive detection and quantification of alpha‐synuclein seeds by qRT‐QuIC.
In: FEBS Open Bio, Bd. 10, Nr. 5: S. 883-893
[PDF, 2MB]
Osterman, Andreas; Ruf, Viktoria C.; Domingo, Cristina; Nitsche, Andreas; Eichhorn, Peter; Zimmermann, Hanna; Seelos, Klaus; Zange, Sabine; Dimitriadis, Konstantinos; Pfister, Hans-Walter; Thye, THorsten; Giese, Armin; Tappe, Dennis und Böhm, Stephan
(2020):
Travel-associated neurological disease terminated in a postmortem diagnosed atypical HSV-1 encephalitis after high-dose steroid therapy - a case report.
In: BMC Infectious Diseases
20:150
[PDF, 1MB]
Stöcklein, Veit Michael; Kellert, Lars; Patzig, Maximilian; Küpper, Clemens; Giese, Armin; Ruf, Viktoria; Weller, Jonathan; Kreth, Friedrich-Wilhelm und Schöberl, Florian
(2020):
Extended stereotactic brain biopsy in suspected primary central nervous system angiitis: good diagnostic accuracy and high safety.
In: Journal of neurology, Bd. 268: S. 367-376
[PDF, 576kB]
Maurer, Andreas; Leonov, Andrei; Ryazanov, Sergey; Herfert, Kristina; Kuebler, Laura; Buss, Sabrina; Schmidt, Felix; Weckbecker, Daniel; Linder, Ruth; Bender, Dirk; Giese, Armin; Pichler, Bernd J. und Griesinger, Christian
(2020):
C-11 Radiolabeling of anle253b: a Putative PET Tracer for Parkinson's Disease That Binds to alpha-Synuclein Fibrils in vitro and Crosses the Blood-Brain Barrier.
In: Chemmedchem, Bd. 15, Nr. 5: S. 411-415
Jecmenica Lukic, Milica; Kurz, Carolin; Respondek, Gesine; Grau-Rivera, Oriol; Compta, Yaroslau; Gelpi, Ellen; Troakes, Claire; Swieten, John C. van; Giese, Armin; Roeber, Sigrun; Arzberger, Thomas und Höglinger, Günter
(2020):
Copathology in Progressive Supranuclear Palsy: Does It Matter?
In: Movement Disorders, Bd. 35, Nr. 6: S. 984-993
[PDF, 829kB]
Kovacs, Gabor G.; Lukic, Milica Jecmenica; Irwin, David J.; Arzberger, Thomas; Respondek, Gesine; Lee, Edward B.; Coughlin, David; Giese, Armin; Grossman, Murray; Kurz, Carolin; McMillan, Corey T.; Gelpi, Ellen; Compta, Yaroslau; Swieten, John C. van; Donker-Kaat, Laura; Troakes, Claire; Al-Sarraj, Safa; Robinson, John L.; Roeber, Sigrun; Xie, Sharon X.; Lee, Virginia M.-Y.; Trojanowski, John Q. und Höglinger, Günter U.
(2020):
Distribution patterns of tau pathology in progressive supranuclear palsy.
In: Acta Neuropathologica, Bd. 140, Nr. 2: S. 99-119
[PDF, 13MB]
Camilleri, Angelique; Ghio, Stephanie; Caruana, Mario; Weckbecker, Daniel; Schmidt, Felix; Kamp, Frits; Leonov, Andrei; Ryazanov, Sergey; Griesinger, Christian; Giese, Armin; Cauchi, Ruben J. und Vassallo, Neville
(2020):
Tau-induced mitochondrial membrane perturbation is dependent upon cardiolipin.
In: Biochimica et Biophysica Acta-Biomembranes, Bd. 1862, Nr. 2, 183064
Grimm, Max-Joseph; Respondek, Gesine; Stamelou, Maria; Arzberger, Thomas; Ferguson, Leslie; Gelpi, Ellen; Giese, Armin; Grossman, Murray; Irwin, David J.; Pantelyat, Alexander; Rajput, Alex; Roeber, Sigrun; Swieten, John C. van; Troakes, Claire; Meissner, Wassilios G.; Nilsson, Christer; Piot, Ines; Compta, Yaroslau; Rowe, James B. und Höglinger, Günter U.
(2020):
Clinical Conditions "Suggestive of Progressive Supranuclear Palsy"-Diagnostic Performance.
In: Movement Disorders, Bd. 35, Nr. 12: S. 2301-2313
Noerenberg, Dominik; Schmidt, Felix; Schinke, Karin; Frenzel, Thomas; Pietsch, Hubertus; Giese, Armin; Ertl-Wagner, Birgit und Levin, Johannes
(2020):
Investigation of potential adverse central nervous system effects after long term oral administration of gadolinium in mice.
In: PLOS One
15(4), e0231495
[PDF, 1MB]
Lemos, Miguel; Venezia, Serena; Refolo, Violetta; Heras-Garvin, Antonio; Schmidhuber, Sabine; Giese, Armin; Leonov, Andrei; Ryazanov, Sergey; Griesinger, Christian; Galabova, Gergana; Staffler, Guenther; Wenning, Gregor Karl und Stefanova, Nadia
(2020):
Targeting alpha-synuclein by PD03 AFFITOPE (R) and Anle138b rescues neurodegenerative pathology in a model of multiple system atrophy: clinical relevance.
In: Translational Neurodegeneration, Bd. 9, Nr. 1, 38
Nuebling, Georg S.; Plesch, Eva; Ruf, Viktoria C.; Hoegen, Tobias; Lorenzl, Stefan; Kamp, Frits; Giese, Armin und Levin, Johannes
(2020):
Binding of Metal-Ion-Induced Tau Oligomers to Lipid Surfaces Is Enhanced by GSK-3 beta-Mediated Phosphorylation.
In: ACS Chemical Neuroscience, Bd. 11, Nr. 6: S. 880-887
Palleis, Carla; Morenas-Rodriguez, Estrella; Martinez Murcia, Francisco Jesus; Giese, Armin; Nuscher, Brigitte; Haass, Christian; Höglinger, Günter; Bötzel, Kai und Levin, Johannes
(2020):
Longitudinal correlation between neurofilament light chain and UMSARS in Multiple System Atrophy.
In: Clinical Neurology and Neurosurgery, Bd. 195, 105924
[PDF, 345kB]
Levin, Johannes; Maaß, Sylvia; Schuberth, Madeleine; Giese, Armin; Bötzel, Kai; Ertl-Wagner, Birgit und Höglinger, Günter ORCID: https://orcid.org/0000-0001-7587-6187
(2019):
Safety and efficacy of epigallocatechin gallate in multiple system atrophy (PROMESA): a randomised, double-blind, placebo-controlled trial.
In: The Lancet Neurology, Bd. 18, Nr. 8: S. 724-735
Saravanan, Manikam S.; Ryazanov, Sergey; Leonov, Andrei; Nicolai, Janine; Praest, Patrique; Giese, Armin; Winter, Roland; Khemtemourian, Lucie; Griesinger, Christian und Killian, J. Antoinette
(2019):
The small molecule inhibitor anle145c thermodynamically traps human islet amyloid peptide in the form of non-cytotoxic oligomers.
In: Scientific Reports, Bd. 9, 19023
[PDF, 1MB]
Wegrzynowici, Michal; Bar-On, Dana; Calo, Laura; Anichtchik, Oleg; Iovino, Mariangela; Xia, Jing; Ryazanov, Sergey; Leonov, Andrei; Giese, Armin; Dalley, Jeffrey W.; Griesinger, Christian; Ashery, Uri und Spillantini, Maria Grazia
(2019):
Depopulation of dense alpha-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson's disease model.
In: Acta Neuropathologica, Bd. 138, Nr. 4: S. 575-595
Respondek, Gesine; Grimm, Max-Joseph; Piot, Ines; Arzberger, Thomas; Compta, Yaroslau; Englund, Elisabet; Ferguson, Leslie W.; Gelpi, Ellen; Roeber, Sigrun; Giese, Armin; Grossman, Murray; Irwin, David J.; Meissner, Wassilios G.; Nilsson, Christer; Pantelyat, Alexander; Rajput, Alex; van Swieten, John C.; Troakes, Claire; Höglinger, Guenter U.; Aiba, Ikuko; Antonini, Angelo; Barone, Paolo; Bhatia, Kailash P.; Boxer, Adam K.; Colosimo, Carlo; Corvol, Jean Christophe; Dickson, Dennis W.; Golbe, Lawrence; Hopfner, Franziska; Josephs, Keith A.; Kassubek, Jan; Kovacs, Gabor G.; Lang, Anthony E.; Levin, Johannes; Litvan, Irene; Hollerhage, Matthias; McFarland, Nikolaus; Morris, Huw R.; Müller, Ulrich; Oertel, Wolfgang H.; Rowe, James B.; Sakakibara, Ruji; Schellenberg, Gerard; Stamelou, Maria; van Eimeren, Thilo; Wenning, Gregor K. und Whitwell, Jennifer L.
(2019):
Validation of the movement disorder society criteria for the diagnosis of 4-repeat tauopathies.
In: Movement Disorders, Bd. 35, Nr. 1: S. 171-176
Ghio, Stephanie; Camilleri, Angelique; Caruana, Mario; Ruf, Viktoria C.; Schmidt, Felix; Leonov, Andrei; Ryazanov, Sergey; Griesinger, Christian; Cauchi, Ruben J.; Kamp, Frits; Giese, Armin und Vassallo, Neville
(2019):
Cardiolipin Promotes Pore-Forming Activity of Alpha-Synuclein Oligomers in Mitochondrial Membranes.
In: ACS Chemical Neuroscience, Bd. 10, Nr. 8: S. 3815-3829
Grimm, Max-Joseph; Respondek, Gesine; Stamelou, Maria; Arzberger, Thomas; Ferguson, Leslie; Gelpi, Ellen; Giese, Armin; Grossman, Murray; Irwin, David J.; Pantelyat, Alexander; Rajput, Alex; Roeber, Sigrun; van Swieten, John C.; Troakes, Claire; Antonini, Angelo; Bhatia, Kailash P.; Colosimo, Carlo; van Eimeren, Thilo; Kassubek, Jan; Levin, Johannes; Meissner, Wassilios G.; Nilsson, Christer; Oertel, Wolfgang H.; Piot, Ines; Poewe, Werner; Wenning, Gregor K.; Boxer, Adam; Golbe, Lawrence I.; Josephs, Keith A.; Litvan, Irene; Morris, Huw R.; Whitwell, Jennifer L.; Compta, Yaroslau; Corvol, Jean-Christophe; Lang, Anthony E.; Rowe, James B.; Höglinger, Guenter U.; Boxer, Adam L.; Rajput, Alex; Pantelyat, Alexander; Antonini, Angelo; Lang, Anthony E.; Giese, Armin; Colosimo, Carlo; Nilsson, Christer; Troakes, Claire; Irwin, David J.; Dickson, Dennis W.; Gelpi, Ellen; Respondek, Gesine; Wenning, Gregor K.; Höglinger, Guenter U.; Morris, Huw R.; Aiba, Ikuko; Litvan, Irene; Rowe, James B.; Kassubek, Jan; Corvol, Jean-Christophe; Whitwell, Jennifer L.; Levin, Johannes; van Swieten, John; Bhatia, Kailash P.; Josephs, Keith A.; Golbe, Lawrence I.; Stamelou, Maria; Grossman, Murray; van Eimeren, Thilo; Arzberger, Thomas; Müller, Ulrich; Meissner, Wassilios G.; Poewe, Werner; Oertel, Wolfgang H. und Compta, Yaroslau
(2019):
How to apply the movement disorder society criteria for diagnosis of progressive supranuclear palsy.
In: Movement Disorders, Bd. 34, Nr. 8: S. 1228-1232
Brendel, Matthias; Deussing, Maximilian; Blume, Tanja; Kaiser, Lena; Probst, Federico; Overhoff, Felix; Peters, Finn; Ungern-Sternberg, Barbara von; Ryazanov, Sergey; Leonov, Andrei; Griesinger, Christian; Zwergal, Andreas; Levin, Johannes; Bartenstein, Peter; Yakushev, Igor; Cumming, Paul; Boening, Guido; Ziegler, Sibylle; Herms, Jochen; Giese, Armin und Rominger, Axel
(2019):
Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer's disease tau.
In: Alzheimer's Research & Therapy, Bd. 11, 67
[PDF, 7MB]
Bartels, Martin; Weckbecker, Daniel; Kuhn, Peer-Hendrik; Ryazanov, Sergey; Leonov, Andrei; Griesinger, Christian; Lichtenthaler, Stefan F.; Boetzel, Kai und Giese, Armin
(2019):
Iron-mediated aggregation and toxicity in a novel neuronal cell culture model with inducible alpha-synuclein expression.
In: Scientific Reports, Bd. 9, 9100
[PDF, 7MB]
Ruf, Viktoria C.; Nuebling, Georg S.; Willikens, Sophia; Shi, Son; Schmidt, Felix; Levin, Johannes; Boetzel, Kai; Kamp, Frits und Giese, Armin
(2019):
Different Effects of alpha-Synuclein Mutants on Lipid Binding and Aggregation Detected by Single Molecule Fluorescence Spectroscopy and ThT Fluorescence-Based Measurements.
In: ACS Chemical Neuroscience, Bd. 10, Nr. 3: S. 1649-1659
Borggraefe, Ingo; Tacke, Moritz; Gerstl, Lucia; Leiz, Steffen; Coras, Roland; Blumcke, Ingmar; Giese, Armin; Ertl-Wagner, Birgit; Thiel, Christian T.; Noachtar, Soheyl und Peraud, Aurelia
(2019):
Epilepsy surgery in the first months of life: a large type IIb focal cortical dysplasia causing neonatal drug-resistant epilepsy.
In: Epileptic Disorders, Bd. 21, Nr. 1: S. 122-127
Suchorska, Bogdana; Schueller, Ulrich; Biczok, Annamaria; Lenski, Markus; Albert, Nathalie L. ORCID: https://orcid.org/0000-0003-0953-7624; Giese, Armin; Kreth, Friedrich-Wilhelm; Ertl-Wagner, Birgit; Tonn, Jörg-Christian und Ingrisch, Michael
(2019):
Contrast enhancement is a prognostic factor in IDH1/2 mutant, but not in wild-type WHO grade II/III glioma as confirmed by machine learning.
In: European Journal of Cancer, Bd. 107: S. 15-27
Reiner, Anne M.; Schmidt, Felix; Ryazanov, Sergey; Leonov, Andrei; Weckbecker, Daniel; Deeg, Andreas A.; Griesinger, Christian; Giese, Armin und Zinth, Wolfgang
(2018):
Photophysics of diphenyl-pyrazole compounds in solutions and alpha-synuclein aggregates.
In: Biochimica et Biophysica Acta-General Subjects, Bd. 1862, Nr. 4: S. 800-807
Gasparoni, Gilles; Bultmann, Sebastian; Lutsik, Pavlo; Kraus, Theo F. J.; Sordon, Sabrina; Vlcek, Julia; Dietinger, Vanessa; Steinmaurer, Martina; Haider, Melanie; Mulholland, Christopher B.; Arzberger, Thomas; Röber, Sigrun; Riemenschneider, Matthias; Kretzschmar, Hans A.; Giese, Armin; Leonhardt, Heinrich und Walter, Jörn
(2018):
DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
In: Epigenetics & Chromatin
11:41
[PDF, 6MB]
Böck, Julia; Remmele, Christian W.; Dittrich, Marcus; Müller, Tobias; Kondova, Ivanela; Persengiev, Stephan; Bontrop, Ronald E.; Ade, Carsten P.; Kraus, Theo F. J.; Giese, Armin; El Hajj, Nady; Schneider, Eberhard und Haaf, Thomas
(2018):
Cell Type and Species-specific Patterns in Neuronal and Non-neuronal Methylomes of Human and Chimpanzee Cortices.
In: Cerebral Cortex, Bd. 28, Nr. 10: S. 3724-3739
Schnell, Oliver; Albrecht, Valerie; Pfirrmann, David; Eigenbrod, Sabina; Krebs, Bjarne; Romagna, Alexander; Siller, Sebastian; Giese, Armin; Tonn, Jörg-Christian und Schichor, Christian
(2018):
MGMT promoter methylation is not correlated with integrin expression in malignant gliomas: clarifying recent clinical trial results.
In: Medical Oncology, Bd. 35, Nr. 7, 103
Steinacker, Petra; Verde, Federico; Fang, Lubin; Feneberg, Emily; Oeckl, Patrick; Roeber, Sigrun; Anderl-Straub, Sarah; Danek, Adrian; Diehl-Schmid, Janine; Fassbender, Klaus; Fliessbach, Klaus; Foerstl, Hans; Giese, Armin; Jahn, Holger; Kassubek, Jan; Kornhuber, Johannes; Landwehrmeyer, G. Bernhard; Lauer, Martin; Pinkhardt, Elmar Hans; Prudlo, Johannes; Rosenbohm, Angela; Schneider, Anja; Schröter, Matthias L.; Tumani, Hayrettin; Arnim, Christine A. F. von; Weishaupt, Jochen; Weydt, Patrick; Ludolph, Albert C.; Yilmazer Hanke, Deniz und Otto, Markus
(2018):
Chitotriosidase (CHIT1) is increased in microglia and macrophages in spinal cord of amyotrophic lateral sclerosis and cerebrospinal fluid levels correlate with disease severity and progression.
In: Journal of Neurology Neurosurgery and Psychiatry, Bd. 89, Nr. 3: S. 239-247
[PDF, 2MB]
Biczok, Annamaria; Kraus, Theo; Suchorska, Bogdana; Terpolilli, Nicole A.; Thorsteinsdottir, Jun; Giese, Armin; Tonn, Jörg C. und Schichor, Christian
(2018):
TERT promoter mutation is associated with worse prognosis in WHO grade II and III meningiomas.
In: Journal of Neuro-Oncology, Bd. 139, Nr. 3: S. 671-678
Suchorska, Bogdana; Giese, Armin; Biczok, Annamaria; Unterrainer, Marcus; Weller, Michael; Drexler, Mark; Bartenstein, Peter; Schüller, Ulrich; Tonn, Jörg-Christian und Albert, Nathalie L. ORCID: https://orcid.org/0000-0003-0953-7624
(2018):
Identification of time-to-peak on dynamic F-18-FET-PET as a prognostic marker specifically in IDH1/2 mutant diffuse astrocytoma.
In: Neuro-Oncology, Bd. 20, Nr. 2: S. 279-288
Hernandez, Ana Martinez; Urbanke, Hendrik; Gillman, Alan L.; Lee, Joon; Ryazanov, Sergey; Agbemenyah, Hope Y.; Benito, Eva; Jain, Gaurav; Kaurani, Lalit; Grigorian, Gayane; Leonov, Andrei; Rezaei-Ghaleh, Nasrollah; Wilken, Petra; Arce, Fernando Teran; Wagner, Jens; Fuhrman, Martin; Caruana, Mario; Camilleri, Angelique; Vassallo, Neville; Zweckstetter, Markus; Benz, Roland; Giese, Armin; Schneider, Anja; Korte, Martin; Lal, Ratnesh; Griesinger, Christian; Eichele, Gregor und Fischer, Andre
(2018):
The diphenylpyrazole compound anle138b blocks A beta channels and rescues disease phenotypes in a mouse model for amyloid pathology.
In: EMBO Molecular Medicine, Bd. 10, Nr. 1: S. 32-47
[PDF, 1MB]
Baiardi, Simone; Redaelli, Veronica; Ripellino, Paolo; Rossi, Marcello; Franceschini, Alessia; Moggio, Maurizio; Sola, Patrizia; Ladogana, Anna; Fociani, Paolo; Magherini, Anna; Capellari, Sabina; Giese, Armin; Caughey, Byron; Caroppo, Paola und Parchi, Piero
(2018):
Prion-related peripheral neuropathy in sporadic Creutzfeldt-Jakob disease.
In: Journal of neurology, neurosurgery, and psychiatry
[PDF, 3MB]
Winkelmann, Isabel; Unterrainer, Marcus; Suchorska, Bogdana; Wenter, Vera; Sosnova, Marketa; Tonn, Jörg; Giese, Armin; Bartenstein, Peter und Albert, Nathalie L. ORCID: https://orcid.org/0000-0003-0953-7624
(2017):
F-18-FET PET-based biological tumor volume of glioma: comparison of early vs. standard summation images.
In: Journal of Nuclear Medicine, Bd. 58
Dietrich, Olaf; Levin, Johannes; Ahmadi, Seyed-Ahmad; Plate, Annika; Reiser, Maximilian F.; Bötzel, Kai; Giese, Armin und Ertl-Wagner, Birgit
(2017):
MR imaging differentiation of Fe2+ and Fe3+ based on relaxation and magnetic susceptibility properties.
In: Neuroradiology, Bd. 59, Nr. 4: S. 403-409
Blumenstock, Sonja; Rodrigues, Eva F.; Peters, Finn; Blazquez-Llorca, Lidia; Schmidt, Felix; Giese, Armin und Herms, Jochen
(2017):
Seeding and transgenic overexpression of alpha-synuclein triggers dendritic spine pathology in the neocortex.
In: Embo Molecular Medicine, Bd. 9, Nr. 5: S. 716-731
[PDF, 2MB]
Eigenbrod, Sabina; Frick, Petra; Bertsch, Uwe; Mitteregger-Kretzschmar, Gerda; Mielke, Janina; Maringer, Marko; Piening, Niklas; Hepp, Alexander; Daude, Nathalie; Windl, Otto; Levin, Johannes; Giese, Armin; Sakthivelu, Vignesh; Tatzelt, Jörg; Kretzschmar, Hans und Westaway, David
(2017):
Substitutions of PrP N-terminal histidine residues modulate scrapie disease pathogenesis and incubation time in transgenic mice.
In: PLOS One
12(12), e0188989
[PDF, 16MB]
Höglinger, Günter U.; Respondek, Gesine; Stamelou, Maria; Kurz, Carolin; Josephs, Keith A.; Lang, Anthony E.; Mollenhauer, Brit; Müller, Ulrich; Nilsson, Christer; Whitwell, Jennifer L.; Arzberger, Thomas; Englund, Elisabet; Gelpi, Ellen; Giese, Armin; Irwin, David J.; Meissner, Wassilios G.; Pantelyat, Alexander; Rajput, Alex; Swieten, John C. van; Troakes, Claire; Antonini, Angelo; Bhatia, Kailash P.; Bordelon, Yvette; Compta, Yaroslau; Corvol, Jean-Christophe; Colosimo, Carlo; Dickson, Dennis W.; Dodel, Richard; Ferguson, Leslie; Grossman, Murray; Kassubek, Jan; Krismer, Florian; Levin, Johannes; Lorenzl, Stefan; Morris, Huw R.; Nestor, Peter; Örtel, Wolfgang H.; Pöwe, Werner; Rabinovici, Gil; Rowe, James B.; Schellenberg, Gerard D.; Seppi, Klaus; Eimeren, Thilo van; Wenning, Gregor K.; Boxer, Adam L.; Golbe, Lawrence I. und Litvan, Irene
(2017):
Clinical Diagnosis of Progressive Supranuclear Palsy: The Movement Disorder Society Criteria.
In: Movement Disorders, Bd. 32, Nr. 6: S. 853-864
Albert, Nathalie L. ORCID: https://orcid.org/0000-0003-0953-7624; Suchorska, Bogdana; Unterrainer, Marcus; Giese, Armin; Biczok, Annamaria; Weller, Michael; Schaaller, Ulrich; Bartenstein, Peter und Tonn, Jörg
(2017):
Prognostic value of dynamic F-18-FET PET in the light of the updated 2016 WHO classification for gliomas.
In: Journal of Nuclear Medicine, Bd. 58
Respondek, Gesine; Kurz, Carolin; Arzberger, Thomas; Compta, Yaroslau; Englund, Elisabet; Ferguson, Leslie W.; Gelpi, Ellen; Giese, Armin; Irwin, David J.; Meissner, Wassilios G.; Nilsson, Christer; Pantelyat, Alexander; Rajput, Alex; Swieten, John C. van; Troakes, Claire; Josephs, Keith A.; Lang, Anthony E.; Mollenhauer, Brit; Müller, Ulrich; Whitwell, Jennifer L.; Antonini, Angelo; Bhatia, Kailash P.; Bordelon, Yvette; Corvol, Jean-Christophe; Colosimo, Carlo; Dodel, Richard; Grossman, Murray; Kassubek, Jan; Krismer, Florian; Levin, Johannes; Lorenzl, Stefan; Morris, Huw; Nestor, Peter; Oertel, Wolfgang H.; Rabinovici, Gil D.; Rowe, James B.; Eimeren, Thilo van; Wenning, Gregor K.; Boxer, Adam; Golbe, Lawrence I.; Litvan, Irene; Stamelou, Maria und Höglinger, Günter U.
(2017):
Which Ante Mortem Clinical Features Predict Progressive Supranuclear Palsy Pathology?
In: Movement Disorders, Bd. 32, Nr. 7: S. 995-1005
Turriani, Elisa; Lazaro, Diana F.; Ryazanov, Sergey; Leonov, Andrei; Giese, Armin; Schön, Margarete; Schön, Michael P.; Griesinger, Christian; Outeiro, Tiago F.; Arndt-Jovin, Donna J. und Becker, Dorothea
(2017):
Treatment with diphenyl-pyrazole compound anle138b/c reveals that alpha-synuclein protects melanoma cells from autophagic cell death.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 114, Nr. 25, E4971-E4977
Hagel, Christian; Buslei, Rolf; Buchfelder, Michael; Fahlbusch, Rudolf; Bergmann, Markus; Giese, Armin; Flitsch, Jörg; Luedecke, Dieter K.; Glatzel, Markus und Säger, Wolfgang
(2017):
Immunoprofiling of glial tumours of the neurohypophysis suggests a common pituicytic origin of neoplastic cells.
In: Pituitary, Bd. 20, Nr. 2: S. 211-217
Cescatti, Maura; Saverioni, Daniela; Capellari, Sabina; Tagliavini, Fabrizio; Kitamoto, Tetsuyuki; Ironside, James W.; Giese, Armin und Parchi, Piero
(Juli 2016):
Analysis of Conformational Stability of Abnormal Prion Protein Aggregates across the Spectrum of Creutzfeldt-Jakob Disease Prions.
In: Journal of Virology, Bd. 90, Nr. 14: S. 6244-6254
Füllhase, Claudius; Schreiber, Andrea; Giese, Armin; Schmidt, Michael; Montorsi, Francesco; Gratzke, Christian; La Croce, Giovanni; Castiglione, Fabio; Stief, Christian und Hedlund, Petter
(2016):
Spinal neuronal cannabinoid receptors mediate urodynamic effects of systemic fatty acid amide hydrolase (FAAH) inhibition in rats.
In: Neurourology and Urodynamics, Bd. 35, Nr. 4: S. 464-470
Steinacker, Petra; Blennow, Kaj; Halbgebauer, Steffen; Shi, Song; Ruf, Viktoria; Oeckl, Patrick; Giese, Armin; Kuhle, Jens; Slivarichova, Dana; Zetterberg, Henrik und Otto, Markus
(2016):
Neurofilaments in blood and CSF for diagnosis and prediction of onset in Creutzfeldt-Jakob disease.
In: Scientific Reports, Bd. 6, 38737
[PDF, 583kB]
Kretner, Benedikt; Trambauer, Johannes; Fukumori, Akio; Mielke, Janina; Kuhn, Peer-Hendrik; Kremmer, Elisabeth; Giese, Armin; Lichtenthaler, Stefan F.; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Arzberger, Thomas und Steiner, Harald
(2016):
Generation and deposition of A43 by the virtually inactive presenilin-1 L435F mutant contradicts the presenilin loss-of-function hypothesis of Alzheimer's disease.
In: Embo Molecular Medicine, Bd. 8, Nr. 5: S. 458-465
[PDF, 1MB]
Fellner, Lisa; Kuzdas-Wood, Daniela; Levin, Johannes; Ryazanov, Sergey; Leonov, Andrei; Griesinger, Christian; Giese, Armin; Wenning, Gregor K. und Stefanova, Nadia
(2016):
Anle138b Partly Ameliorates Motor Deficits Despite Failure of Neuroprotection in a Model of Advanced Multiple System Atrophy.
In: Frontiers in Neuroscience, Bd. 10, 99
[PDF, 5MB]
Vallabh Minikel, Eric; Vallabh, Sonia M.; Lek, Monkol; Estrada, Karol; Samocha, Kaitlin E.; Sathirapongsasuti, J. Fah; McLean, Cory Y.; Tung, Joyce Y.; Yu, Linda P. C.; Gambetti, Pierluigi; Blevins, Janis; Zhang, Shulin; Cohen, Yvonne; Chen, Wei; Yamada, Masahito; Hamaguchi, Tsuyoshi; Sanjo, Nobuo; Mizusawa, Hidehiro; Nakamura, Yosikazu; Kitamoto, Tetsuyuki; Collins, Steven J.; Boyd, Alison; Will, Robert G.; Knight, Richard; Ponto, Claudia; Zerr, Inga; Kraus, Theo F. J.; Eigenbrod, Sabina; Giese, Armin; Calero, Miguel; de Pedro-Cuesta, Jesus; HaiK, Stephane; Laplanche, Jean-Louis; Bouaziz-Amar, Elodie; Brandel, Jean-Philippe; Capellari, Sabina; Parchi, Piero; Poleggi, Anna; Ladogana, Anna; O'Donnell-Luria, Anne H.; Karczewski, Konrad J.; Marshall, Jamie L.; Boehnke, Michael; Laakso, Markku; Mohlke, Karen L.; Kähler, Anna; Chambert, Kimberly; McCarroll, Steven; Sullivan, Patrick F.; Hultman, Christina M.; Purcell, Shaun M.; Sklar, Pamela; Lee, Sven J. van der; Rozemuller, Annemieke; Jansen, Casper; Hofman, Albert; Kraaij, Robert; Rooij, Jeroen G. J. van; Ikram, M. Arfan; Uitterlinden, Andre G.; Duijn, Cornelia M. van; Daly, Mark J. und MacArthur, Daniel G.
(2016):
Quantifying prion disease penetrance using large population control cohorts.
In: Science Translational Medicine, Bd. 8, Nr. 322, 322ra9
Kretner, Benedikt; Trambauer, Johannes; Fukumori, Akio; Mielke, Janina; Kuhn, Peer-Hendrik; Kremmer, Elisabeth; Giese, Armin; Lichtenthaler, Stefan F.; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Arzberger, Thomas und Steiner, Harald
(2016):
Generation and deposition of A43 by the virtually inactive presenilin-1 L435F mutant contradicts the presenilin loss-of-function hypothesis of Alzheimer's disease.
In: Embo Molecular Medicine, Bd. 8, Nr. 5: S. 458-465
Sadasivam, Saravanan Manikam; Ryazanov, Sergey; Leonov, Andrei; Roeters, Steven; Wouterson, Sander; Giese, Armin; Griesinger, Christian und Killian, J. Antoinette
(2016):
Effect of the Novel Amyloid Inhibitor "anle145c" on Aggregation of Islet Amyloid Polypeptide and how it is Modulated by Membranes.
In: Biophysical Journal, Bd. 110, Nr. 3:
420A-420A
Tatura, Roman; Kraus, Theo; Giese, Armin; Arzberger, Thomas; Buchholz, Malte; Höglinger, Guenter und Müller, Ulrich
(2016):
Parkinson's disease: SNCA-, PARK2-, and LRRK2- targeting microRNAs elevated in cingulate gyrus.
In: Parkinsonism & Related Disorders, Bd. 33: S. 115-121
Suchorska, Bogdana; Kraus, Theo; Biczok, Annamaria; Weller, Michael; Unterrainer, Marcus; Schüller, Ulrich; Schmid-Tannwald, Christine; Bartenstein, Peter; Giese, Armin; Albert, Nathalie L. ORCID: https://orcid.org/0000-0003-0953-7624 und Tonn, Joerg-Christian
(2016):
18FET-PET uptake dynamics serves as an additional imaging biomarker in astrocytomas with IDH1/2 mutation and no LOH1p/19q.
In: Neuro-Oncology, Bd. 18: S. 131-132
Schnell, Oliver; Thorsteinsdottir, Jun; Fleischmann, Daniel Felix; Lenski, Markus; Abenhardt, Wolfgang; Giese, Armin; Tonn, Jörg-Christian; Belka, Claus; Kreth, Friedrich Wilhelm und Niyazi, Maximilian
(2016):
Re-irradiation strategies in combination with bevacizumab for recurrent malignant glioma.
In: Journal of Neuro-Oncology, Bd. 130, Nr. 3: S. 591-599
Spadaro, Melania; Gerdes, Lisa Ann; Mayer, Marie C.; Ertl-Wagner, Birgit; Laurent, Sarah; Krumbholz, Markus; Breithaupt, Constanze; Högen, Tobias; Straube, Andreas; Giese, Armin; Hohlfeld, Reinhard; Lassmann, Hans; Meinl, Edgar und Kümpfel, Tania
(2015):
Histopathology and clinical course of MOG-antibody-associated encephalomyelitis.
In: Annals of Clinical and Translational Neurology, Bd. 2, Nr. 3: S. 295-301
Nübling, Georg Sebastian; Levin, Johannes; Bader, Benedikt; Lorenzl, Stefan; Hillmer, Andreas; Högen, Tobias; Kamp, Frits und Giese, Armin
(2014):
Modelling Ser129 Phosphorylation Inhibits Membrane Binding of Pore-Forming Alpha-Synuclein Oligomers.
In: PLOS ONE
9(6), e98906
[PDF, 691kB]
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