Anzahl der Publikationen: 39
Zeitschriftenartikel
Rossi, Matteo; Altea-Manzano, Patricia; Demicco, Margherita; Doglioni, Ginevra; Bornes, Laura; Fukano, Marina; Vandekeere, Anke; Cuadros, Alejandro M.; Fernandez-Garcia, Juan; Riera-Domingo, Carla; Jauset, Cristina; Planque, Melanie; Alkan, H. Furkan; Nittner, David; Zuo, Dongmei; Broadfield, Lindsay A.; Parik, Sweta; Pane, Antonino Alejandro; Rizzollo, Francesca; Rinaldi, Gianmarco; Zhang, Tao; Teoh, Shao Thing; Aurora, Arin B.; Karras, Panagiotis; Vermeire, Ines; Broekaert, Dorien; Elsen, Joke van; Knott, Maximilian M. L.; Orth, Martin F.; Demeyer, Sofie; Eelen, Guy; Dobrolecki, Lacey E.; Bassez, Ayse; Brussel, Thomas van; Sotlar, Karl; Lewis, Michael T.; Bartsch, Harald; Wuhrer, Manfred; Veelen, Peter van; Carmeliet, Peter; Cools, Jan; Morrison, Sean J.; Marine, Jean-Christophe; Lambrechts, Diether; Mazzone, Massimiliano; Hannon, Gregory J.; Lunt, Sophia Y.; Grünewald, Thomas G. P.; Park, Morag; Rheenen, Jacco van und Fendt, Sarah-Maria
(2022):
PHGDH heterogeneity potentiates cancer cell dissemination and metastasis.
In: Nature, Bd. 605, Nr. 7911: S. 747-753
Kommoss, Felix K. F.; Stichel, Damian; Schrimpf, Daniel; Kriegsmann, Mark; Tessier-Cloutier, Basile; Talhouk, Aline; McAlpine, Jessica N.; Chang, Kenneth T. E.; Sturm, Dominik; Pfister, Stefan M.; Romero-Perez, Laura; Kirchner, Thomas; Grünewald, Thomas G. P.; Buslei, Rolf; Sinn, Hans-Peter; Mechtersheimer, Gunhild; Schirmacher, Peter; Schmidt, Dietmar; Lehr, Hans-Anton; Sahm, Felix; Huntsman, David G.; Gilks, C. Blake; Kommoss, Friedrich; Deimling, Andreas von und Koelsche, Christian
(2020):
DNA methylation-based profiling of uterine neoplasms: a novel tool to improve gynecologic cancer diagnostics.
In: Journal of Cancer Research and Clinical Oncology, Bd. 146, Nr. 1: S. 97-104
Rodríguez‐Núñez, Pablo; Romero‐Pérez, Laura; Amaral, Ana T.; Puerto‐Camacho, Pilar; Jordán, Carmen; Marcilla, David; Grünewald, Thomas G. P.; Alonso, Javier; Alava, Enrique de und Díaz‐Martín, Juan
(2020):
Hippo pathway effectors YAP1/TAZ induce an EWS–FLI1‐opposing gene signature and associate with disease progression in Ewing sarcoma.
In: Journal of Pathology, Bd. 250, Nr. 4: S. 374-386
[PDF, 3MB]
Gerke, Julia S.; Orth, Martin F.; Tolkach, Yuri; Romero‐Pérez, Laura; Wehweck, Fabienne S.; Stein, Stefanie; Musa, Julian; Knott, Maximilian M.L.; Hölting, Tilman L.B.; Li, Jing; Sannino, Giuseppina; Marchetto, Aruna; Ohmura, Shunya; Cidre‐Aranaz, Florencia; Müller‐Nurasyid, Martina; Strauch, Konstantin; Stief, Christian; Kristiansen, Glen; Kirchner, Thomas; Buchner, Alexander und Grünewald, Thomas G. P.
(2020):
Integrative clinical transcriptome analysis reveals TMPRSS2‐ERG dependency of prognostic biomarkers in prostate adenocarcinoma.
In: International Journal of Cancer, Bd. 146, Nr. 7: S. 2036-2046
[PDF, 10MB]
Aynaud, Marie-Ming; Mirabeau, Olivier; Gruel, Nadege; Grossetete, Sandrine; Boeva, Valentina; Durand, Simon; Surdez, Didier; Saulnier, Olivier; Zaidi, Sakina; Gribkova, Svetlana; Fouche, Aziz; Kairov, Ulykbek; Raynal, Virginie; Tirode, Franck; Grünewald, Thomas G. P.; Bohec, Mylene; Baulande, Sylvain; Janoueix-Lerosey, Isabelle; Vert, Jean-Philippe; Barillot, Emmanuel; Delattre, Olivier und Zinovyev, Andrei
(2020):
Transcriptional Programs Define Intratumoral Heterogeneity of Ewing Sarcoma at Single-Cell Resolution.
In: Cell Reports, Bd. 30, Nr. 6: S. 1767-1779
Triki, Mouna; Rinaldi, Gianmarco; Planque, Melanie; Broekaert, Dorien; Winkelkotte, Alina M.; Maier, Carina R.; Raman, Sudha Janaki; Vandekeere, Anke; Elsen, Joke van; Orth, Martin F.; Grünewald, Thomas G. P.; Schulze, Almut und Fendt, Sarah-Maria
(2020):
mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.
In: Cell Reports, Bd. 31, Nr. 12, 107806
Marchetto, Aruna; Ohmura, Shunya; Orth, Martin F.; Knott, Maximilian M. L.; Colombo, Maria V.; Arrigoni, Chiara; Bardinet, Victor; Saucier, David; Wehweck, Fabienne S.; Li, Jing; Stein, Stefanie; Gerke, Julia S.; Baldauf, Michaela C.; Musa, Julian; Dallmayer, Marlene; Romero-Perez, Laura; Hoelting, Tilman L. B.; Amatruda, James F.; Cossarizza, Andrea; Henssen, Anton G.; Kirchner, Thomas; Moretti, Matteo; Cidre-Aranaz, Florencia; Sannino, Giuseppina und Grünewald, Thomas G. P.
(2020):
Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma.
In: Nature Communications, Bd. 11, Nr. 1, 2423
[PDF, 2MB]
Stenger, Dana; Stief, Tanja A.; Kaeuferle, Theresa; Willier, Semjon; Rataj, Felicitas; Schober, Kilian; Vick, Binje; Lotfi, Ramin; Wagner, Beate; Grünewald, Thomas G. P.; Kobold, Sebastian; Busch, Dirk H.; Jeremias, Irmela; Blaeschke, Franziska und Feuchtinger, Tobias
(2020):
Endogenous TCR promotes in vivo persistence of CD19-CAR-T cells compared to a CRISPR/Cas9-mediated TCR knockout CAR.
In: Blood, Bd. 136, Nr. 12: S. 1407-1418
Lin, Shu-Hong; Sampson, Joshua N.; Grünewald, Thomas G. P.; Surdez, Didier; Reynaud, Stephanie; Mirabeau, Olivier; Karlins, Eric; Rubio, Rebeca Alba; Zaidi, Sakina; Grossetete-Lalami, Sandrine; Ballet, Stelly; Lapouble, Eve; Laurence, Valerie; Michon, Jean; Pierron, Gaelle; Kovar, Heinrich; Kontny, Udo; Gonzalez-Neira, Anna; Alonso, Javier; Patino-Garcia, Ana; Corradini, Nadege; Berard, Perrine Marec; Miller, Jeremy; Freedman, Neal D.; Rothman, Nathaniel; Carter, Brian D.; Dagnall, Casey L.; Burdett, Laurie; Jones, Kristine; Manning, Michelle; Wyatt, Kathleen; Zhou, Weiyin; Yeager, Meredith; Cox, David G.; Hoover, Robert N.; Khan, Javed; Armstrong, Gregory T.; Leisenring, Wendy M.; Bhatia, Smita; Robison, Leslie L.; Kulozik, Andreas E.; Kriebel, Jennifer; Meitinger, Thomas; Metzler, Markus; Krumbholz, Manuela; Hartmann, Wolfgang; Strauch, Konstantin; Kirchner, Thomas; Dirksen, Uta; Mirabello, Lisa; Tucker, Margaret A.; Tirode, Franck; Morton, Lindsay M.; Chanock, Stephen J.; Delattre, Olivier und Machiela, Mitchell J.
(2020):
Low-frequency variation near common germline susceptibility loci are associated with risk of Ewing sarcoma.
In: PLOS One
15(9), e0237792
[PDF, 1MB]
Orth, Martin F.; Hoelting, Tilman L. B.; Dallmayer, Marlene; Wehweck, Fabienne S.; Paul, Tanja; Musa, Julian; Baldauf, Michaela C.; Surdez, Didier; Delattre, Olivier; Knott, Maximilian M. L.; Romero-Perez, Laura; Kasan, Merve; Cidre-Aranaz, Florencia; Gerke, Julia S.; Ohmura, Shunya; Li, Jing; Marchetto, Aruna; Henssen, Anton G.; Oezen, Oezlem; Sugita, Shintaro; Hasegawa, Tadashi; Kanaseki, Takayuki; Bertram, Stefanie; Dirksen, Uta; Hartmann, Wolfgang; Kirchner, Thomas und Grünewald, Thomas G. P.
(2020):
High Specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG Positive Ewing Sarcoma.
In: Cancers, Bd. 12, Nr. 3, 644
Galai, Geut; Ben-David, Hila; Levin, Liron; Orth, Martin F.; Grünewald, Thomas G. P.; Pilosof, Shai; Bershtein, Shimon und Rotblat, Barak
(2020):
Pan-Cancer Analysis of Mitochondria Chaperone-Client Co-Expression Reveals Chaperone Functional Partitioning.
In: Cancers, Bd. 12, Nr. 4, 825
Steinestel, Konrad; Trautmann, Marcel; Jansen, Esther-Pia; Dirksen, Uta; Rehkaemper, Jan; Mikesch, Jan-Henrik; Gerke, Julia S.; Orth, Martin F.; Sannino, Giuseppina; Arteaga, Maria-Francisca; Rossig, Claudia; Wardelmann, Eva; Grünewald, Thomas G. P. und Hartmann, Wolfgang
(2019):
Focal adhesion kinase confers pro-migratory and antiapoptotic properties and is a potential therapeutic target in Ewing sarcoma.
In: Molecular Oncology, Bd. 14, Nr. 2: S. 248-260
Koelsche, Christian; Kriegsmann, Mark; Kommoss, Felix K. F.; Stichel, Damian; Kriegsmann, Katharina; Vokuhl, Christian; Grünewald, Thomas G. P.; Romero-Perez, Laura; Kirchner, Thomas; de Alava, Enrique; Diaz-Martin, Juan; Hartmann, Wolfgang; Baumhoer, Daniel; Antonescu, Cristina R.; Szuhai, Karoly; Flucke, Uta; Dirksen, Uta; Pfister, Stefan M.; Jones, David T. W.; Mechtersheimer, Gunhild und Deimling, Andreas von
(2019):
DNA methylation profiling distinguishes Ewing-like sarcoma with EWSR1-NFATc2 fusion from Ewing sarcoma.
In: Journal of Cancer Research and Clinical Oncology, Bd. 145, Nr. 5: S. 1273-1281
Dallmayer, Marlene; Li, Jing; Ohmura, Shunya; Rubio, Rebeca Alba; Baldauf, Michaela C.; Hoelting, Tilman L. B.; Musa, Julian; Knott, Max M. L.; Stein, Stefanie; Cidre-Aranaz, Florencia; Wehweck, Fabienne S.; Romero-Perez, Laura; Gerke, Julia S.; Orth, Martin F.; Marchetto, Aruna; Kirchner, Thomas; Bach, Horacio; Sannino, Giuseppina und Grünewald, Thomas G. P.
(2019):
Targeting the CALCB/RAMP1 axis inhibits growth of Ewing sarcoma.
In: Cell Death & Disease, Bd. 10, 116
Orth, Martin F.; Gerke, Julia S.; Knoesel, Thomas; Altendorf-Hofmann, Annelore; Musa, Julian; Alba-Rubio, Rebeca; Stein, Stefanie; Hoelting, Tilman L. B.; Cidre-Aranaz, Florencia; Romero-Perez, Laura; Dallmayer, Marlene; Baldauf, Michaela C.; Marchetto, Aruna; Sannino, Giuseppina; Knott, Maximilian M. L.; Wehweck, Fabienne; Ohmura, Shunya; Li, Jing; Hakozaki, Michiyuki; Kirchner, Thomas; Dandekar, Thomas; Butt, Elke und Grünewald, Thomas G. P.
(2019):
Functional genomics identifies AMPD2 as a new prognostic marker for undifferentiated pleomorphic sarcoma.
In: International Journal of Cancer, Bd. 144, Nr. 4: S. 859-867
Vriens, Kim; Christen, Stefan; Parik, Sweta; Broekaert, Dorien; Yoshinaga, Kazuaki; Talebi, Ali; Dehairs, Jonas; Escalona-Noguero, Carmen; Schmieder, Roberta; Cornfield, Thomas; Charlton, Catriona; Romero-Perez, Laura; Rossi, Matteo; Rinaldi, Gianmarco; Orth, Martin F.; Boon, Ruben; Kerstens, Axelle; Kwan, Suet Ying; Faubert, Brandon; Mendez-Lucas, Andres; Kopitz, Charlotte C.; Chen, Ting; Fernandez-Garcia, Juan; Duarte, Joao A. G.; Schmitz, Arndt A.; Steigemann, Patrick; Najimi, Mustapha; Haegebarth, Andrea; Van Ginderachter, Jo A.; Sokal, Etienne; Gotoh, Naohiro; Wong, Kwok-Kin; Verfaillie, Catherine; Derua, Rita; Munck, Sebastian; Yuneva, Mariia; Beretta, Laura; DeBerardinis, Ralph J.; Swinnen, Johannes V.; Hodson, Leanne; Cassiman, David; Verslype, Chris; Christian, Sven; Grünewald, Sylvia; Grünewald, Thomas G. P. und Fendt, Sarah-Maria
(2019):
Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity.
In: Nature, Bd. 566, Nr. 7744
Jones, David T. W.; Banito, Ana; Grünewald, Thomas G. P.; Haber, Michelle; Jaeger, Natalie; Kool, Marcel; Milde, Till; Molenaar, Jan J.; Nabbi, Arash; Pugh, Trevor J.; Schleiermacher, Gudrun; Smith, Malcolm A.; Westermann, Frank und Pfister, Stefan M.
(2019):
Molecular characteristics and therapeutic vulnerabilities across paediatric solid tumours.
In: Nature Reviews Cancer, Bd. 19, Nr. 8: S. 420-438
Romero-Perez, Laura; Surdez, Didier; Brunet, Erika; Delattre, Olivier und Grünewald, Thomas G. P.
(2019):
STAG Mutations in Cancer.
In: Trends in Cancer, Bd. 5, Nr. 8: S. 506-520
Sannino, Giuseppina; Marchetto, Aruna; Ranft, Andreas; Jabar, Susanne; Zacherl, Constanze; Alba-Rubio, Rebeca; Stein, Stefanie; Wehweck, Fabienne S.; Kiran, Merve M.; Hoelting, Tilman L. B.; Musa, Julian; Romero-Perez, Laura; Cidre-Aranaz, Florencia; Knott, Maximilian M. L.; Li, Jing; Jürgens, Heribert; Sastre, Ana; Alonso, Javier; Da Silveira, Willian; Hardiman, Gary; Gerke, Julia S.; Orth, Martin F.; Hartmann, Wolfgang; Kirchner, Thomas; Ohmura, Shunya; Dirksen, Uta und Grünewald, Thomas G. P.
(2019):
Gene expression and immunohistochemical analyses identify SOX2 as major risk factor for overall survival and relapse in Ewing sarcoma patients.
In: Ebiomedicine, Bd. 47: S. 156-162
Musa, Julian; Cidre-Aranaz, Florencia; Aynaud, Marie-Ming; Orth, Martin F.; Knott, Maximilian M. L.; Mirabeau, Olivier; Mazor, Gal; Varon, Mor; Hoelting, Tilman L. B.; Grossetete, Sandrine; Gartlgruber, Moritz; Surdez, Didier; Gerke, Julia S.; Ohmura, Shunya; Marchetto, Aruna; Dallmayer, Marlene; Baldauf, Michaela C.; Stein, Stefanie; Sannino, Giuseppina; Li, Jing; Romero-Perez, Laura; Westermann, Frank; Hartmann, Wolfgang; Dirksen, Uta; Gymrek, Melissa; Anderson, Nathaniel D.; Shlien, Adam; Rotblat, Barak; Kirchner, Thomas; Delattre, Olivier und Grünewald, Thomas G. P.
(2019):
Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes.
In: Nature Communications, Bd. 10, 4128
[PDF, 2MB]
Lamprecht, Sebastian; Kaller, Markus; Schmidt, Eva Marina; Blaj, Cristina; Schiergens, Tobias S.; Engel, Jutta; Jung, Andreas; Hermeking, Heiko; Grünewald, Thomas G. P.; Kirchner, Thomas und Horst, David
(2018):
PBX3 Is Part of an EMT Regulatory Network and Indicates Poor Outcome in Colorectal Cancer.
In: Clinical cancer research, Bd. 24, Nr. 8: S. 1974-1986
Froelich, Matthias F.; Stintzing, Sebastian; Kumbrink, Jörg; Grünewald, Thomas G. P.; Mansmann, Ulrich; Heinemann, Volker; Kirchner, Thomas und Jung, Andreas
(2018):
The DNA-polymorphism rs849142 is associated with skin toxicity induced by targeted anti-EGFR therapy using cetuximab.
In: OncoTarget, Bd. 9, Nr. 54: S. 30279-30288
[PDF, 3MB]
Boeva, Valentina; Louis-Brennetot, Caroline; Peltier, Agathe; Durand, Simon; Pierre-Eugene, Cecile; Raynal, Virginie; Etchevers, Heather C.; Thomas, Sophie; Lermine, Alban; Daudigeos-Dubus, Estelle; Geoerger, Birgit; Orth, Martin F.; Grünewald, Thomas G. P.; Diaz, Elise; Ducos, Bertrand; Surdez, Didier; Carcaboso, Angel M.; Medvedeva, Irina; Deller, Thomas; Combaret, Valerie; Lapouble, Eve; Pierron, Gaelle; Grossetete-Lalami, Sandrine; Baulande, Sylvain; Schleiermacher, Gudrun; Barillot, Emmanuel; Rohrer, Hermann; Delattre, Olivier und Janoueix-Lerosey, Isabelle
(2017):
Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries.
In: Nature Genetics, Bd. 49, Nr. 9: S. 1408-1413
Elia, Ilaria; Brökärt, Dorien; Christen, Stefan; Boon, Ruben; Radaelli, Enrico; Orth, Martin F.; Verfaillie, Catherine; Grünewald, Thomas G. P. und Fendt, Sarah-Maria
(2017):
Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells.
In: Nature Communications, Bd. 8, 15267
[PDF, 2MB]
Kirschner, Andreas; Thiede, Melanie; Grünewald, Thomas G. P.; Rubio, Rebeca Alba; Richter, Günther H. S.; Kirchner, Thomas; Busch, Dirk H.; Burdach, Stefan und Thiel, Uwe
(2017):
Pappalysin-1 T cell receptor transgenic allo-restricted T cells kill Ewing sarcoma in vitro and in vivo.
In: Oncoimmunology, Bd. 6, Nr. 2, e1273301
Schirmer, David; Grünewald, Thomas G. P.; Klar, Richard; Schmidt, Oxana; Wohlleber, Dirk; Rubio, Rebeca Alba; Uckert, Wolfgang; Thiel, Uwe; Bohne, Felix; Busch, Dirk H.; Krackhardt, Angela M.; Burdach, Stefan und Richter, Günther H. S.
(2016):
Transgenic antigen-specific, HLA-A*02:01-allo-restricted cytotoxic T cells recognize tumor-associated target antigen STEAP1 with high specificity.
In: Oncoimmunology, Bd. 5, Nr. 6, e1175795
Sannino, Giuseppina; Pasqualini, Lorenza; Ricciardelli, Eugenia; Montilla, Patricia; Soverchia, Laura; Ruggeri, Barbara; Falcinelli, Silvia; Renzi, Alessandra; Ludka, Colleen; Kirchner, Thomas; Grünewald, Thomas G. P.; Ciccocioppo, Roberto; Ubaldi, Massimo und Hardiman, Gary
(2016):
Acute stress enhances the expression of neuroprotection- and neurogenesis-associated genes in the hippocampus of a mouse restraint model.
In: Oncotarget, Bd. 7, Nr. 8: S. 8455-8465
Kovar, Heinrich; Amatruda, James; Brunet, Erika; Burdach, Stefan; Cidre-Aranaz, Florencia; de Alava, Enrique; Dirksen, Uta; Ent, Wietske van der; Grohar, Patrick; Grünewald, Thomas G. P.; Helman, Lee; Houghton, Peter; Iljin, Kristiina; Korsching, Eberhard; Ladanyi, Marc; Lawlor, Elizabeth; Lessnick, Stephen; Ludwig, Joseph; Meltzer, Paul; Metzler, Markus; Mora, Jaume; Moriggl, Richard; Nakamura, Takuro; Papamarkou, Theodore; Sarikas, Branka Radic; Rédini, Francoise; Richter, Guenther H. S.; Rossig, Claudia; Schadler, Keri; Schäfer, Beat W.; Scotlandi, Katia; Sheffield, Nathan C.; Shelat, Anang; Snaar-Jagalska, Ewa; Sorensen, Poul; Stegmaier, Kimberly; Stewart, Elizabeth; Sweet-Cordero, Alejandro; Szuhai, Karoly; Tirado, Oscar M.; Tirode, Franck; Toretsky, Jeffrey; Tsafou, Kalliopi; Üren, Aykut; Zinovyev, Andrei und Delattre, Olivier
(2016):
The second European interdisciplinary Ewing sarcoma research summit - A joint effort to deconstructing the multiple layers of a complex disease.
In: Oncotarget, Bd. 7, Nr. 8: S. 8613-8624
Kirschner, Andreas; Thiede, Melanie; Blaeschke, Franziska; Richter, Günther H. S.; Gerke, Julia S.; Baldauf, Michaela C.; Grünewald, Thomas G. P.; Busch, Dirk H.; Burdach, Stefan und Thiel, Uwe
(2016):
Lysosome-associated membrane glycoprotein 1 predicts fratricide amongst T cell receptor transgenic CD8(+) T cells directed against tumor-associated antigens.
In: Oncotarget, Bd. 7, Nr. 35: S. 56584-56597
Buchbeitrag
Diese Liste wurde am
Sat Jan 18 20:29:23 2025 CET
erstellt.