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Eine Ebene höherGruppiert nach: Dokumententyp |
Veröffentlichungsdatum
Anzahl der Publikationen: 79
2023
Gottschlich, Adrian; Thomas, Moritz; Gruenmeier, Ruth; Lesch, Stefanie; Rohrbacher, Lisa; Igl, Veronika; Briukhovetska, Daria; Benmebarek, Mohamed-Reda; Vick, Binje; Dede, Sertac; Mueller, Katharina; Xu, Tao; Dhoqina, Dario; Maerkl, Florian; Robinson, Sophie; Sendelhofert, Andrea; Schulz, Heiko; Umut, Oeykue; Kavaka, Vladyslav; Tsiverioti, Christina Angeliki; Carlini, Emanuele; Nandi, Sayantan; Strzalkowski, Thaddaeus; Lorenzini, Theo; Stock, Sophia; Mueller, Philipp Jie; Doerr, Janina; Seifert, Matthias; Cadilha, Bruno L.; Brabenec, Ruben; Roeder, Natalie; Rataj, Felicitas; Nueesch, Manuel; Modemann, Franziska; Wellbrock, Jasmin; Fiedler, Walter; Kellner, Christian; Beltran, Eduardo; Herold, Tobias; Paquet, Dominik; Jeremias, Irmela; von Baumgarten, Louisa; Endres, Stefan; Subklewe, Marion; Marr, Carsten und Kobold, Sebastian
(2023):
Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia.
In: Nature Biotechnology, Bd. 41, Nr. 11:
1618-+
[PDF, 7MB]
Batcha, Aarif M. N. 
ORCID: https://orcid.org/0000-0002-7972-7506; Buckup, Nele; Bamopoulos, Stefanos A ORCID: https://orcid.org/0000-0002-5997-7735; Jurinovic, Vindi; Rothenberg-Thurley, Maja; Gittinger, Hanna; Ksienzyk, Bianka; Dufour, Annika; Schneider, Stephanie; Kontro, Mika; Saad, Joseph ORCID: https://orcid.org/0000-0001-7701-0328; Heckman, Caroline A. ORCID: https://orcid.org/0000-0002-4324-8706; Sauerland, Cristina M.; Görlich, Dennis ORCID: https://orcid.org/0000-0002-2574-9419; Berdel, Wolfgang E. ORCID: https://orcid.org/0000-0002-3030-6567; Wörmann, Bernhard; Krug, Utz; Braess, Jan; Mansmann, Ulrich Robert ORCID: https://orcid.org/0000-0002-9955-8906; Hiddemann, Wolfgang; Spiekermann, Karsten ORCID: https://orcid.org/0000-0002-5139-4957; Metzeler, Klaus H. ORCID: https://orcid.org/0000-0003-3920-7490 und Herold, Tobias ORCID: https://orcid.org/0000-0002-9615-9432
(2023):
Germline SNPs previously implicated as prognostic biomarkers do not associate with outcomes in intensively treated AML.
In: Blood Advances, Bd. 7, Nr. 6: S. 1040-1044
ORCID: https://orcid.org/0000-0002-7972-7506; Buckup, Nele; Bamopoulos, Stefanos A ORCID: https://orcid.org/0000-0002-5997-7735; Jurinovic, Vindi; Rothenberg-Thurley, Maja; Gittinger, Hanna; Ksienzyk, Bianka; Dufour, Annika; Schneider, Stephanie; Kontro, Mika; Saad, Joseph ORCID: https://orcid.org/0000-0001-7701-0328; Heckman, Caroline A. ORCID: https://orcid.org/0000-0002-4324-8706; Sauerland, Cristina M.; Görlich, Dennis ORCID: https://orcid.org/0000-0002-2574-9419; Berdel, Wolfgang E. ORCID: https://orcid.org/0000-0002-3030-6567; Wörmann, Bernhard; Krug, Utz; Braess, Jan; Mansmann, Ulrich Robert ORCID: https://orcid.org/0000-0002-9955-8906; Hiddemann, Wolfgang; Spiekermann, Karsten ORCID: https://orcid.org/0000-0002-5139-4957; Metzeler, Klaus H. ORCID: https://orcid.org/0000-0003-3920-7490 und Herold, Tobias ORCID: https://orcid.org/0000-0002-9615-9432
(2023):
Germline SNPs previously implicated as prognostic biomarkers do not associate with outcomes in intensively treated AML.
In: Blood Advances, Bd. 7, Nr. 6: S. 1040-1044
Pastore, Friederike ORCID: https://orcid.org/0000-0002-2220-2346; Gittinger, Hanna; Raab, Susanne; Tschuri, Sebastian; Ksienzyk, Bianka; Konstandin, Nikola P.; Schneider, Stephanie; Rothenberg‐Thurley, Maja; Horny, Hans‐Peter; Werner, Martin; Sauerland, Maria C. ORCID: https://orcid.org/0000-0002-8748-8218; Amler, Susanne ORCID: https://orcid.org/0000-0001-6903-2906; Görlich, Dennis ORCID: https://orcid.org/0000-0002-2574-9419; Berdel, Wolfgang E. ORCID: https://orcid.org/0000-0002-3030-6567; Wörmann, Bernhard ORCID: https://orcid.org/0000-0003-2273-5502; Braess, Jan; Hiddemann, Wolfgang; Tischer, Johanna ORCID: https://orcid.org/0000-0003-1821-1976; Herold, Tobias ORCID: https://orcid.org/0000-0002-9615-9432; Metzeler, Klaus H. ORCID: https://orcid.org/0000-0003-3920-7490 und Spiekermann, Karsten ORCID: https://orcid.org/0000-0002-5139-4957
(2023):
Acute megakaryoblastic leukaemia shows high frequency of chromosome 1q aberrations and dismal outcome.
In: British Journal of Haematology, Bd. 202, Nr. 6: S. 1165-1177
[PDF, 1MB]
ORCID: https://orcid.org/0000-0002-2220-2346; Gittinger, Hanna; Raab, Susanne; Tschuri, Sebastian; Ksienzyk, Bianka; Konstandin, Nikola P.; Schneider, Stephanie; Rothenberg‐Thurley, Maja; Horny, Hans‐Peter; Werner, Martin; Sauerland, Maria C. ORCID: https://orcid.org/0000-0002-8748-8218; Amler, Susanne ORCID: https://orcid.org/0000-0001-6903-2906; Görlich, Dennis ORCID: https://orcid.org/0000-0002-2574-9419; Berdel, Wolfgang E. ORCID: https://orcid.org/0000-0002-3030-6567; Wörmann, Bernhard ORCID: https://orcid.org/0000-0003-2273-5502; Braess, Jan; Hiddemann, Wolfgang; Tischer, Johanna ORCID: https://orcid.org/0000-0003-1821-1976; Herold, Tobias ORCID: https://orcid.org/0000-0002-9615-9432; Metzeler, Klaus H. ORCID: https://orcid.org/0000-0003-3920-7490 und Spiekermann, Karsten ORCID: https://orcid.org/0000-0002-5139-4957
(2023):
Acute megakaryoblastic leukaemia shows high frequency of chromosome 1q aberrations and dismal outcome.
In: British Journal of Haematology, Bd. 202, Nr. 6: S. 1165-1177
[PDF, 1MB]
2022
Zeller, Tobias; Lutz, Sebastian; Münnich, Ira A.; Windisch, Roland; Hilger, Patricia; Herold, Tobias; Tahiri, Natyra; Banck, Jan C.; Weigert, Oliver; Moosmann, Andreas; von Bergwelt-Baildon, Michael; Flamann, Cindy; Bruns, Heiko; Wichmann, Christian; Baumann, Niklas; Valerius, Thomas; Schewe, Denis M.; Peipp, Matthias; Rösner, Thies; Humpe, Andreas und Kellner, Christian
(27. Oktober 2022):
Dual checkpoint blockade of CD47 and LILRB1 enhances CD20 antibody-dependent phagocytosis of lymphoma cells by macrophages.
In: Frontiers in Immunology, Bd. 13
[PDF, 21MB]
Kerbs, Paul; Vosberg, Sebastian; Krebs, Stefan; Graf, Alexander; Blum, Helmut; Swoboda, Anja; Batcha, Aarif M. N.; Mansmann, Ulrich; Metzler, Dirk; Heckman, Caroline A.; Herold, Tobias und Greif, Philipp A.
(2022):
Fusion gene detection by RNA-sequencing complements diagnostics of acute myeloid leukemia and identifies recurring NRIP1-MIR99AHG rearrangements.
In: Haematologica, Bd. 107, Nr. 1: S. 100-111
[PDF, 1MB]
Zeller, Christina ORCID: https://orcid.org/0000-0003-1834-965X; Richter, Daniel ORCID: https://orcid.org/0000-0003-1302-9083; Jurinovic, Vindi; Valtierra-Gutiérrez, Ilse A. ORCID: https://orcid.org/0000-0003-4128-5914; Jayavelu, Ashok Kumar; Mann, Matthias; Bagnoli, Johannes W. ORCID: https://orcid.org/0000-0003-0393-6157; Hellmann, Ines ORCID: https://orcid.org/0000-0003-0588-1313; Herold, Tobias ORCID: https://orcid.org/0000-0002-9615-9432; Enard, Wolfgang ORCID: https://orcid.org/0000-0002-4056-0550; Vick, Binje ORCID: https://orcid.org/0000-0003-1956-2778 und Jeremias, Irmela ORCID: https://orcid.org/0000-0003-1773-7677
(2022):
Adverse stem cell clones within a single patient’s tumor predict clinical outcome in AML patients.
In: Journal of Hematology & Oncology, Bd. 15, 25
[PDF, 1MB]
ORCID: https://orcid.org/0000-0003-1834-965X; Richter, Daniel ORCID: https://orcid.org/0000-0003-1302-9083; Jurinovic, Vindi; Valtierra-Gutiérrez, Ilse A. ORCID: https://orcid.org/0000-0003-4128-5914; Jayavelu, Ashok Kumar; Mann, Matthias; Bagnoli, Johannes W. ORCID: https://orcid.org/0000-0003-0393-6157; Hellmann, Ines ORCID: https://orcid.org/0000-0003-0588-1313; Herold, Tobias ORCID: https://orcid.org/0000-0002-9615-9432; Enard, Wolfgang ORCID: https://orcid.org/0000-0002-4056-0550; Vick, Binje ORCID: https://orcid.org/0000-0003-1956-2778 und Jeremias, Irmela ORCID: https://orcid.org/0000-0003-1773-7677
(2022):
Adverse stem cell clones within a single patient’s tumor predict clinical outcome in AML patients.
In: Journal of Hematology & Oncology, Bd. 15, 25
[PDF, 1MB]
Heinrich, Kathrin; Miller-Phillips, Lisa; Ziemann, Frank; Hasselmann, Korbinian; Rühlmann, Katharina; Flach, Madeleine; Biro, Dorottya; Bergwelt-Baildon, Michael von; Holch, Julian; Herold, Tobias; Baumgarten, Louisa von; Greif, Philip A. ORCID: https://orcid.org/0000-0002-3744-7936; Jeremias, Irmela; Wuerstlein, Rachel; Casuscelli, Jozefina; Spitzweg, Christine; Seidensticker, Max; Renz, Bernhard; Corradini, Stefanie; Baumeister, Philipp; Goni, Elisabetta; Tufman, Amanda; Jung, Andreas; Kumbrink, Jörg; Kirchner, Thomas; Klauschen, Frederick; Metzeler, Klaus H.; Heinemann, Volker und Westphalen, C. Benedikt ORCID: https://orcid.org/0000-0002-5310-3754
(2022):
Lessons learned: the first consecutive 1000 patients of the CCCMunich(LMU) Molecular Tumor Board.
In: Journal of Cancer Research and Clinical Oncology, Bd. 149, Nr. 5: S. 1905-1915
[PDF, 728kB]
ORCID: https://orcid.org/0000-0002-3744-7936; Jeremias, Irmela; Wuerstlein, Rachel; Casuscelli, Jozefina; Spitzweg, Christine; Seidensticker, Max; Renz, Bernhard; Corradini, Stefanie; Baumeister, Philipp; Goni, Elisabetta; Tufman, Amanda; Jung, Andreas; Kumbrink, Jörg; Kirchner, Thomas; Klauschen, Frederick; Metzeler, Klaus H.; Heinemann, Volker und Westphalen, C. Benedikt ORCID: https://orcid.org/0000-0002-5310-3754
(2022):
Lessons learned: the first consecutive 1000 patients of the CCCMunich(LMU) Molecular Tumor Board.
In: Journal of Cancer Research and Clinical Oncology, Bd. 149, Nr. 5: S. 1905-1915
[PDF, 728kB]
Alcazer, Vincent; Bonaventura, Paola; Tonon, Laurie; Michel, Emilie; Mutez, Virginie; Fabres, Clementine; Chuvin, Nicolas; Boulos, Rasha; Estornes, Yann; Maguer-Satta, Veronique; Geistlich, Kevin; Viari, Alain; Metzeler, Klaus H.; Hiddemann, Wolfgang; Batch, Aarif M. N.; Herold, Tobias; Caux, Christophe und Depil, Stephane
(2022):
HERVs characterize normal and leukemia stem cells and represent a source of shared epitopes for cancer immunotherapy.
In: American Journal of Hematology, Bd. 97, Nr. 9: S. 1200-1214
Rausch, Christian; Hiddemann, Wolfgang; Bergwelt-Baildon, Michael von; Spiekermann, Karsten und Herold, Tobias
(2022):
Akute Myeloische Leukämien – Update 2022.
In: Deutsche Medizinische Wochenschrift, Bd. 147, Nr. 17: S. 1108-1113
Middeke, Jan M.; Metzeler, Klaus H.; Roellig, Christoph; Kraemer, Michael; Eckardt, Jan-Niklas; Stasik, Sebastian; Greif, Philipp A.; Spiekermann, Karsten; Rothenberg-Thurley, Maja; Krug, Utz; Braess, Jan; Kraemer, Alwin; Hochhaus, Andreas; Bruemmendorf, Tim H.; Naumann, Ralph; Steffen, Bjoern; Einsele, Hermann; Schaich, Markus; Burchert, Andreas; Neubauer, Andreas; Goerlich, Dennis; Sauerland, Cristina; Schaefer-Eckart, Kerstin; Schliemann, Christoph; Krause, Stefan W.; Haenel, Mathias; Frickhofen, Norbert; Noppeney, Richard; Kaiser, Ulrich; Kaufmann, Martin; Kunadt, Desiree; Woermann, Bernhard; Sockel, Katja; Bonin, Malte von; Herold, Tobias; Mueller-Tidow, Carsten; Platzbecker, Uwe; Berdel, Wolfgang E.; Serve, Hubert; Baldus, Claudia D.; Ehninger, Gerhard; Schetelig, Johannes; Hiddemann, Wolfgang; Bornhaeuser, Martin; Stoelzel, Friedrich und Thiede, Christian
(2022):
Differential impact of IDH1/2 mutational subclasses on outcome in adult AML: results from a large multicenter study.
In: Blood Advances, Bd. 6, Nr. 5: S. 1394-1405
Kunadt, Desiree; Stasik, Sebastian; Metzeler, Klaus H.; Roellig, Christoph; Schliemann, Christoph; Greif, Philipp A.; Spiekermann, Karsten; Rothenberg-Thurley, Maja; Krug, Utz; Braess, Jan; Kraemer, Alwin; Hochhaus, Andreas; Scholl, Sebastian; Hilgendorf, Inken; Bruemmendorf, Tim H.; Jost, Edgar; Steffen, Bjoern; Bug, Gesine; Einsele, Hermann; Goerlich, Dennis; Sauerland, Cristina; Schaefer-Eckart, Kerstin; Krause, Stefan W.; Haenel, Mathias; Hanoun, Maher; Kaufmann, Martin; Woermann, Bernhard; Kramer, Michael; Sockel, Katja; Egger-Heidrich, Katharina; Herold, Tobias; Ehninger, Gerhard; Burchert, Andreas; Platzbecker, Uwe; Berdel, Wolfgang E.; Mueller-Tidow, Carsten; Hiddemann, Wolfgang; Serve, Hubert; Stelljes, Matthias; Baldus, Claudia D.; Neubauer, Andreas; Schetelig, Johannes; Thiede, Christian; Bornhaeuser, Martin; Middeke, Jan M. und Stoelzel, Friedrich
(2022):
Impact of IDH1 and IDH2 mutational subgroups in AML patients after allogeneic stem cell transplantation.
In: Journal of Hematology & Oncology, Bd. 15, Nr. 1, 126
Papaioannou, Dimitrios; Ozer, Hatice G.; Nicolet, Deedra; Urs, Amog P.; Herold, Tobias; Mrozek, Krzysztof; Batcha, Aarif M. N.; Metzeler, Klaus H.; Yilmaz, Ayse S.; Volinia, Stefano; Bill, Marius; Kohlschmidt, Jessica; Pietrzak, Maciej; Walker, Christopher J.; Carroll, Andrew J.; Bräss, Jan; Powell, Bayard L.; Eisfeld, Ann-Kathrin; Uy, Geoffrey L.; Wang, Eunice S.; Kolitz, Jonathan E.; Stone, Richard M.; Hiddemann, Wolfgang; Byrd, John C.; Bloomfield, Clara D. und Garzon, Ramiro
(2022):
Clinical and molecular relevance of genetic variants in the non-coding transcriptome of patients with cytogenetically normal acute myeloid leukemia.
In: Haematologica, Bd. 107, Nr. 5: S. 1034-1044
Huang, Han-ying; Wang, Yun; Herold, Tobias; Gale, Robert Peter; Wang, Jing-zi; Li, Liang; Lin, Huan-xin und Liang, Yang
(2022):
A survival prediction model and nomogram based on immune-related gene expression in chronic lymphocytic leukemia cells.
In: Frontiers in Medicine, Bd. 9, 1026812
Antic, Darko; Milic, Natasa; Chatzikonstantinou, Thomas; Scarfo, Lydia; Otasevic, Vladimir; Rajovic, Nina; Allsup, David; Cabrero, Alejandro Alonso; Andres, Martin; Gonzales, Monica Baile; Capasso, Antonella; Collado, Rosa; Cordoba, Raul; Cuellar-Garcia, Carolina; Correa, Juan Gonzalo; De Paoli, Lorenzo; De Paolis, Maria Rosaria; Del Poeta, Giovanni; Dimou, Maria; Doubek, Michael; Efstathopoulou, Maria; El-Ashwah, Shaimaa; Enrico, Alicia; Espinet, Blanca; Farina, Lucia; Ferrari, Angela; Foglietta, Myriam; Lopez-Garcia, Alberto; Garcia-Marco, Jose A.; Garcia-Serra, Rocio; Gentile, Massimo; Gimeno, Eva; da Silva, Maria Gomes; Gutwein, Odit; Hakobyan, Yervand K.; Herishanu, Yair; Hernandez-Rivas, Jose Angel; Herold, Tobias; Itchaki, Gilad; Jaksic, Ozren; Janssens, Ann; Kalashnikova, Olga B.; Kalicinska, Elzbieta; Kater, Arnon P.; Kersting, Sabina; Koren-Michowitz, Maya; Labrador, Jorge; Lad, Deepesh; Laurenti, Luca; Fresa, Alberto; Levin, Mark-David; Bastida, Carlota Mayor; Malerba, Lara; Marasca, Roberto; Marchetti, Monia; Marquet, Juan; Mihaljevic, Biljana; Milosevic, Ivana; Miras, Fatima; Morawska, Marta; Motta, Marina; Munir, Talha; Murru, Roberta; Nunes, Raquel; Olivieri, Jacopo; Pavlovsky, Miguel Arturo; Piskunova, Inga; Popov, Viola Maria; Quaglia, Francesca Maria; Quaresmini, Giulia; Reda, Gianluigi; Rigolin, Gian Matteo; Shrestha, Amit; Simkovic, Martin; Smirnova, Svetlana; Spacek, Martin; Sportoletti, Paolo; Stanca, Oana; Stavroyianni, Niki; Te Raa, Doreen; Tomic, Kristina; Tonino, Sanne; Trentin, Livio; Spek, Ellen van der; Gelder, Michel van; Varettoni, Marzia; Visentin, Andrea; Vitale, Candida; Vukovic, Vojin; Wasik-Szczepanek, Ewa; Wrobel, Tomasz; San Segundo, Lucrecia Yanez; Yassin, Mohamed; Coscia, Marta; Rambaldi, Alessandro; Montserrat, Emili; Foa, Robin; Cuneo, Antonio; Carrier, Marc; Ghia, Paolo und Stamatopoulos, Kostas
(2022):
Thrombotic and bleeding complications in patients with chronic lymphocytic leukemia and severe COVID-19: a study of ERIC, the European Research Initiative on CLL.
In: Journal of Hematology & Oncology, Bd. 15, Nr. 1, 116
Wirth, Anna-Katharina; Wange, Lucas; Vosberg, Sebastian; Henrich, Kai-Oliver; Rausch, Christian; Oezdemir, Erbey; Zeller, Christina M.; Richter, Daniel; Feuchtinger, Tobias; Kaller, Markus; Hermeking, Heiko; Greif, Philipp A.; Senft, Daniela; Jurinovic, Vindi; Bahrami, Ehsan; Jayavelu, Ashok Kumar; Westermann, Frank; Mann, Matthias; Enard, Wolfgang; Herold, Tobias und Jeremias, Irmela
(2022):
In vivo PDX CRISPR/Cas9 screens reveal mutual therapeutic targets to overcome heterogeneous acquired chemo-resistance.
In: Leukemia, Bd. 36: S. 2863-2874
Leubolt, Georg; Windisch, Roland; Kerbs, Paul; Dutta, Sayantanee; Landspersky, Theresa; Istvanffy, Rouzanna; Chen-Wichmann, Linping; Herold, Tobias; Cusan, Monica; Schotta, Gunnar; Wichmann, Christian; Greif, Philipp A. A.; Monte, Enric Redondo und Oostendorp, Robert A. J.
(2022):
Specific effects of somatic GATA2 zinc finger mutations on erythroid differentiation.
In: Experimental Hematology, Bd. 108: S. 26-35
Grasedieck, Sarah; Cabantog, Ariene; MacPhee, Liam; Im, Junbum; Ruess, Christoph; Demir, Burcu; Sperb, Nadine; Ruecker, Frank G.; Doehner, Konstanze; Herold, Tobias; Pollack, Jonathan R.; Bullinger, Lars; Rouhi, Arefeh und Kuchenbauer, Florian
(2022):
The retinoic acid receptor co-factor NRIP1 is uniquely upregulated and represents a therapeutic target in acute myeloid leukemia with chromosome 3q rearrangements.
In: Haematologica, Bd. 107, Nr. 8: S. 1758-1772
Carlet, Michela; Schmelz, Karin; Vergalli, Jenny; Herold, Tobias; Senft, Daniela; Jurinovic, Vindi; Hoffmann, Thomas; Proba, Jutta; Weichert, Nina; Junghanss, Christian; Roth, Mareike; Eschenburg, Georg; Barz, Malwine; Henze, Guenter; Eckert, Cornelia; Eggert, Angelika; Zuber, Johannes; Hundsdoerfer, Patrick und Jeremias, Irmela
(2022):
X-linked inhibitor of apoptosis protein represents a promising therapeutic target for relapsed/refractory ALL.
In: EMBO Molecular Medicine, Bd. 15, Nr. 1, e14557
2021
Kerbs, Paul; Vosberg, Sebastian; Krebs, Stefan; Graf, Alexander; Blum, Helmut; Swoboda, Anja; Batcha, Aarif M. N.; Mansmann, Ulrich ORCID: https://orcid.org/0000-0002-9955-8906; Metzler, Dirk; Heckman, Caroline A.; Herold, Tobias und Greif, Philipp A.
(2021):
Fusion gene detection by RNA sequencing complements diagnostics of acute myeloid leukemia and identifies recurring NRIP1-MIR99AHG rearrangements.
In: Haematologica
ORCID: https://orcid.org/0000-0002-9955-8906; Metzler, Dirk; Heckman, Caroline A.; Herold, Tobias und Greif, Philipp A.
(2021):
Fusion gene detection by RNA sequencing complements diagnostics of acute myeloid leukemia and identifies recurring NRIP1-MIR99AHG rearrangements.
In: Haematologica
Papaioannou, Dimitrios; Ozer, Hatice G.; Nicolet, Deedra; Urs, Amog P.; Herold, Tobias; Mrózek, Krzysztof; Batcha, Aarif M. N.; Metzeler, Klaus H.; Yilmaz, Ayse S.; Volinia, Stefano; Bill, Marius; Kohlschmidt, Jessica; Pietrzak, Maciej; Walker, Christopher J.; Carroll, Andrew J.; Braess, Jan; Powell, Bayard L.; Eisfeld, Ann-Kathrin; Uy, Geoffrey L.; Wang, Eunice S.; Kolitz, Jonathan E.; Stone, Richard M.; Hiddemann, Wolfgang; Byrd, John C.; Bloomfield, Clara D. und Garzon, Ramiro
(2021):
Clinical and molecular relevance of genetic variants in the non-coding transcriptome of patients with cytogenetically normal acute myeloid leukemia.
In: Haematologica
Moser, Christian; Jurinovic, Vindi; Sagebiel-Kohler, Sabine; Ksienzyk, Bianka; Batcha, Aarif M. N.; Dufour, Annika; Schneider, Stephanie; Rothenberg-Thurley, Maja; Sauerland, Cristina M.; Görlich, Dennis und Herold, Tobias
(2021):
A clinically applicable gene expression-based score predicts resistance to induction treatment in acute myeloid leukemia.
In: Blood Advances, Bd. 5, Nr. 22: S. 4752-4761
Chatzikonstantinou, Thomas; Kapetanakis, Anargyros; Scarfo, Lydia; Karakatsoulis, Georgios; Allsup, David; Alonso Cabrero, Alejandro; Andres, Martin; Antic, Darko; Baile, Monica; Baliakas, Panagiotis; Bron, Dominique; Capasso, Antonella; Chatzileontiadou, Sofia; Cordoba, Raul; Correa, Juan-Gonzalo; Cuellar-Garcia, Carolina; De Paoli, Lorenzo; De Paolis, Maria Rosaria; Del Poeta, Giovanni; Demosthenous, Christos; Dimou, Maria; Donaldson, David; Doubek, Michael; Efstathopoulou, Maria; Eichhorst, Barbara; El-Ashwah, Shaimaa; Enrico, Alicia; Espinet, Blanca; Farina, Lucia; Ferrari, Angela; Foglietta, Myriam; Frederiksen, Henrik; Furstenau, Moritz; Garcia-Marco, Jose A.; Garcia-Serra, Rocio; Gentile, Massimo; Gimeno, Eva; Glenthoj, Andreas; da Silva, Maria Gomes; Gutwein, Odit; Hakobyan, Yervand K.; Herishanu, Yair; Angel Hernandez-Rivas, Jose; Herold, Tobias; Innocenti, Idanna; Itchaki, Gilad; Jaksic, Ozren; Janssens, Ann; Kalashnikova, Olga B.; Kalicinska, Elzbieta; Karlsson, Linda Katharina; Kater, Arnon P.; Kersting, Sabina; Labrador, Jorge; Lad, Deepesh; Laurenti, Luca; Levin, Mark-David; Lista, Enrico; Lopez-Garcia, Alberto; Malerba, Lara; Marasca, Roberto; Marchetti, Monia; Marquet, Juan; Mattsson, Mattias; Mauro, Francesca R.; Milosevic, Ivana; Miras, Fatima; Morawska, Marta; Motta, Marina; Munir, Talha; Murru, Roberta; Niemann, Carsten U.; Rodrigues, Raquel Nunes; Olivieri, Jacopo; Orsucci, Lorella; Papaioannou, Maria; Arturo Pavlovsky, Miguel; Piskunova, Inga; Popov, Viola Maria; Quaglia, Francesca Maria; Quaresmini, Giulia; Qvist, Kristian; Reda, Gianluigi; Rigolin, Gian Matteo; Ruchlemer, Rosa; Saghumyan, Gevorg; Shrestha, Amit; Simkovic, Martin; Spacek, Martin; Sportoletti, Paolo; Stanca, Oana; Stavroyianni, Niki; Tadmor, Tamar; Te Raa, Doreen; Tonino, Sanne H.; Trentin, Livio; Spek, Ellen van der; Gelder, Michel van; Kampen, Roel van; Varettoni, Marzia; Visentin, Andrea; Vitale, Candida; Wasik-Szczepanek, Ewa; Wrobel, Tomasz; Yanez San Segundo, Lucrecia; Yassin, Mohamed; Coscia, Marta; Rambaldi, Alessandro; Montserrat, Emili; Foa, Robin; Cuneo, Antonio; Stamatopoulos, Kostas und Ghia, Paolo
(2021):
COVID-19 severity and mortality in patients with CLL: an update of the international ERIC and Campus CLL study.
In: Leukemia, Bd. 35, Nr. 12: S. 3444-3454
Kempf, Julia M.; Weser, Sabrina; Bartoschek, Michael D.; Metzeler, Klaus H.; Vick, Binje; Herold, Tobias; Voelse, Kerstin; Mattes, Raphael; Scholz, Manuela; Wange, Lucas E.; Festini, Moreno; Ugur, Enes; Roas, Maike; Weigert, Oliver; Bultmann, Sebastian; Leonhardt, Heinrich; Schotta, Gunnar; Hiddemann, Wolfgang; Jeremias, Irmela und Spiekermann, Karsten
(2021):
Loss-of-function mutations in the histone methyltransferase EZH2 promote chemotherapy resistance in AML.
In: Scientific Reports, Bd. 11, Nr. 1, 5838
Moser, Christian; Jurinovic, Vindi; Sagebiel-Kohler, Sabine; Ksienzyk, Bianka; Batcha, Aarif M. N.; Dufour, Annika; Schneider, Stephanie; Rothenberg-Thurley, Maja; Sauerland, Cristina M.; Gorlich, Dennis; Berdel, Wolfgang E.; Krug, Utz; Mansmann, Ulrich; Hiddemann, Wolfgang; Braess, Jan; Spiekermann, Karsten; Greif, Philipp A.; Vosberg, Sebastian; Metzeler, Klaus H.; Kumbrink, Joerg und Herold, Tobias
(2021):
A clinically applicable gene expression-based score predicts resistance to induction treatment in acute myeloid leukemia.
In: Blood Advances, Bd. 5, Nr. 22: S. 4752-4761
Munker, Dieter; Osterman, Andreas; Stubbe, Hans; Muenchhoff, Maximilian; Veit, Tobias; Weinberger, Tobias; Barnikel, Michaela; Mumm, Jan-Niclas; Milger, Katrin; Khatamzas, Elham; Klauss, Sarah; Scherer, Clemens; Hellmuth, Johannes C.; Giessen-Jung, Clemens; Zoller, Michael; Herold, Tobias; Stecher, Stephanie; De Toni, Enrico N.; Schulz, Christian; Kneidinger, Nikolaus; Keppler, Oliver T.; Behr, Jürgen; Mayerle, Julia und Munker, Stefan
(2021):
Dynamics of SARS-CoV-2 shedding in the respiratory tract depends on the severity of disease in COVID-19 patients.
In: European Respiratory Journal, Bd. 58, Nr. 1, 2002724
Wang, Xin; Ros, Uris; Agrawal, Deepti; Keller, Eva C.; Slotta-Huspenina, Julia; Dill, Veronika; Shen, Bo; Shi, Run; Herold, Tobias; Belka, Claus; Misra, Ritu; Bassermann, Florian; Garcia-Saez, Ana J. und Jost, Philipp J.
(2021):
MLKL promotes cellular differentiation in myeloid leukemia by facilitating the release of G-CSF.
In: Cell Death and Differentiation, Bd. 28, Nr. 12: S. 3235-3250
Wang, Yun; Cai, Yan-yu; Herold, Tobias; Nie, Run-cong; Zhang, Yu; Gale, Robert Peter; Metzeler, Klaus H.; Zeng, Yun; Wang, Shun-qing; Pan, Xue-yi; Yang, Tong-hua; Wu, Yuan-bin; Zhang, Qing; Wuxiao, Zhi-jun; Du, Xin; Liang, Zhi-wei; Su, Yong-zhong; Xu, Jing-bo; Wang, Yong-qing; Liu, Ze-lin; Wu, Jian-wei; Zhang, Xiong; Wu, Bing-yi; Xiao, Ruo-zhi; Wang, San-bin; Li, Jin-yuan; Chi, Pei-dong; Zhang, Qian-yi; Chen, Si-liang; Qin, Zhe-yuan; Zhang, Xin-mei; Zhong, Na; Hiddemann, Wolfgang; Liu, Qi-fa; Zhang, Bei und Liang, Yang
(2021):
An Immune Risk Score Predicts Survival of Patients with Acute Myeloid Leukemia Receiving Chemotherapy.
In: Clinical Cancer Research, Bd. 27, Nr. 1: S. 255-266
2020
Anande, G.; Deshpande, Nandan P.; Mareschal, Sylvain; Batcha, Aarif M. N.; Hampton, Henry R.; Herold, Tobias ORCID: https://orcid.org/0000-0002-9615-9432; Lehmann, Sören; Wilkins, Marc R.; Wong, Jason W.H.; Unnikrishnan, Ashwin und Pimanda, John E.
(15. Juli 2020):
RNA Splicing Alterations Induce a Cellular Stress Response Associated with Poor Prognosis in Acute Myeloid Leukemia.
In: Clinical Cancer Research, Bd. 26, Nr. 14: S. 3597-3607
ORCID: https://orcid.org/0000-0002-9615-9432; Lehmann, Sören; Wilkins, Marc R.; Wong, Jason W.H.; Unnikrishnan, Ashwin und Pimanda, John E.
(15. Juli 2020):
RNA Splicing Alterations Induce a Cellular Stress Response Associated with Poor Prognosis in Acute Myeloid Leukemia.
In: Clinical Cancer Research, Bd. 26, Nr. 14: S. 3597-3607
Vaikari, Vijaya Pooja; Du, Yang; Wu, Sharon; Zhang, Tian; Metzeler, Klaus H.; Batcha, Aarif M. N.; Herold, Tobias; Hiddemann, Wolfgang; Akhtari, Mojtaba und Alachkar, Houda
(April 2020):
Clinical and preclinical characterization of CD99 isoforms in acute myeloid leukemia.
In: Haematologica, Bd. 105, Nr. 4
[PDF, 4MB]
Liu, Wen-Hsin; Mrozek-Gorska, Paulina; Wirth, Anna-Katharina; Herold, Tobias; Schwarzkopf, Larissa; Pich, Dagmar; Voelse, Kerstin; Melo-Narvaez, M. Camila; Carlet, Michela; Hammerschmidt, Wolfgang und Jeremias, Irmela
(2020):
Inducible transgene expression in PDX models in vivo identifies KLF4 as a therapeutic target for B-ALL.
In: Biomarker Research, Bd. 8, Nr. 1, 46
Floeth, Matthias; Elges, Sandra; Gerss, Joachim; Schwoeppe, Christian; Kessler, Torsten; Herold, Tobias; Wardelmann, Eva; Berdel, Wolfgang E.; Lenz, Georg; Mikesch, Jan-Henrik; Hartmann, Wolfgang; Schliemann, Christoph und Angenendt, Linus
(2020):
Low-density lipoprotein receptor (LDLR) is an independent adverse prognostic factor in acute myeloid leukaemia.
In: British Journal of Haematology, Bd. 192, Nr. 3: S. 494-503
Herold, Tobias; Wörnle, Markus und Schelling, Jörg
(2020):
COVID-19 aus Sicht der Praxen und Notaufnahmen.
In: Deutsche Medizinische Wochenschrift, Bd. 145, Nr. 15: S. 1080-1085
Rothenburger, Tamara; McLaughlin, Katie-May; Herold, Tobias; Schneider, Constanze; Oellerich, Thomas; Rothweiler, Florian; Feber, Andrew; Fenton, Tim R.; Wass, Mark N.; Keppler, Oliver T.; Michaelis, Martin und Cinatl, Jindrich
(2020):
SAMHD1 is a key regulator of the lineage-specific response of acute lymphoblastic leukaemias to nelarabine.
In: Communications Biology, Bd. 3, Nr. 1
Bamopoulos, Stefanos A.; Batcha, Aarif M. N.; Jurinovic, Vindi; Rothenberg-Thurley, Maja; Janke, Hanna; Ksienzyk, Bianka; Philippou-Massier, Julia; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Schneider, Stephanie; Konstandin, Nikola; Sauerland, Maria Cristina; Görlich, Dennis; Berdel, Wolfgang E.; Woermann, Bernhard J.; Bohlander, Stefan K.; Canzar, Stefan; Mansmann, Ulrich; Hiddemann, Wolfgang; Braess, Jan; Spiekermann, Karsten; Metzeler, Klaus H. und Herold, Tobias
(2020):
Clinical presentation and differential splicing of SRSF2, U2AF1 and SF3B1 mutations in patients with acute myeloid leukemia.
In: Leukemia, Bd. 34, Nr. 10: S. 2621-2634
Herold, Tobias ORCID: https://orcid.org/0000-0002-9615-9432; Rothenberg-Thurley, Maja; Grunwald, Victoria V.; Janke, Hanna; Goerlich, Dennis; Sauerland, Maria C.; Konstandin, Nikola P.; Dufour, Annika; Schneider, Stephanie; Neusser, Michaela; Ksienzyk, Bianka; Greif, Philipp A.; Subklewe, Marion; Faldum, Andreas; Bohlander, Stefan K.; Braess, Jan; Wörmann, Bernhard; Krug, Utz; Berdel, Wolfgang E.; Hiddemann, Wolfgang; Spiekermann, Karsten und Metzeler, Klaus H.
(2020):
Validation and refinement of the revised 2017 European LeukemiaNet genetic risk stratification of acute myeloid leukemia.
In: Leukemia, Bd. 34: S. 3161-3172
[PDF, 2MB]
ORCID: https://orcid.org/0000-0002-9615-9432; Rothenberg-Thurley, Maja; Grunwald, Victoria V.; Janke, Hanna; Goerlich, Dennis; Sauerland, Maria C.; Konstandin, Nikola P.; Dufour, Annika; Schneider, Stephanie; Neusser, Michaela; Ksienzyk, Bianka; Greif, Philipp A.; Subklewe, Marion; Faldum, Andreas; Bohlander, Stefan K.; Braess, Jan; Wörmann, Bernhard; Krug, Utz; Berdel, Wolfgang E.; Hiddemann, Wolfgang; Spiekermann, Karsten und Metzeler, Klaus H.
(2020):
Validation and refinement of the revised 2017 European LeukemiaNet genetic risk stratification of acute myeloid leukemia.
In: Leukemia, Bd. 34: S. 3161-3172
[PDF, 2MB]
Scarfo, Lydia; Chatzikonstantinou, Thomas; Rigolin, Gian Matteo; Quaresmini, Giulia; Motta, Marina; Vitale, Candida; Antonio Garcia-Marco, Jose; Angel Hernandez-Rivas, Jose; Miras, Fatima; Baile, Monica; Marquet, Juan; Niemann, Carsten U.; Reda, Gianluigi; Munir, Talha; Gimeno, Eva; Marchetti, Monia; Quaglia, Francesca Maria; Varettoni, Marzia; Delgado, Julio; Iyengar, Sunil; Janssens, Ann; Marasca, Roberto; Ferrari, Angela; Cuellar-Garcia, Carolina; Itchaki, Gilad; Spacek, Martin; De Paoli, Lorenzo; Laurenti, Luca; Levin, Mark-David; Lista, Enrico; Mauro, Francesca R.; Simkovic, Martin; Spek, Ellen van der; Vandenberghe, Elisabeth; Trentin, Livio; Wasik-Szczepanek, Ewa; Ruchlemer, Rosa; Bron, Dominique; De Paolis, Maria Rosaria; Del Poeta, Giovanni; Farina, Lucia; Foglietta, Myriam; Gentile, Massimo; Herishanu, Yair; Herold, Tobias; Jaksic, Ozren; Kater, Arnon P.; Kersting, Sabina; Malerba, Lara; Orsucci, Lorella; Popov, Viola Maria; Sportoletti, Paolo; Yassin, Mohamed; Pocali, Barbara; Barna, Gabor; Chiarenza, Annalisa; dos Santos, Gimena; Nikitin, Eugene; Andres, Martin; Dimou, Maria; Doubek, Michael; Enrico, Alicia; Hakobyan, Yervand; Kalashnikova, Olga; Ortiz Pareja, Macarena; Papaioannou, Maria; Rossi, Davide; Shah, Nimish; Shrestha, Amit; Stanca, Oana; Stavroyianni, Niki; Strugov, Vladimir; Tam, Constantine; Zdrenghea, Mihnea; Coscia, Marta; Stamatopoulos, Kostas; Rossi, Giuseppe; Rambaldi, Alessandro; Montserrat, Emili; Foa, Robin; Cuneo, Antonio und Ghia, Paolo
(2020):
COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus.
In: Leukemia, Bd. 34, Nr. 9: S. 2354-2363
Bamezai, Shiva; Demir, Deniz; Pulikkottil, Alex Jose; Ciccarone, Fabio; Fischbein, Elena; Sinha, Amit; Borga, Chiara; te Kronnie, Geertruy; Meyer, Lueder-Hinrich; Mohr, Fabian; Goetze, Maria; Caiafa, Paola; Debatin, Klaus-Michael; Doehner, Konstanze; Doehner, Hartmut; Gonzalez-Menendez, Irene; Quintanilla-Fend, Leticia; Herold, Tobias; Jeremias, Irmela; Feuring-Buske, Michaela; Buske, Christian und Rawat, Vijay P. S.
(2020):
TET1 promotes growth of T-cell acute lymphoblastic leukemia and can be antagonized via PARP inhibition.
In: Leukemia, Bd. 35, Nr. 2: S. 389-403
Opatz, Sabrina; Bamopoulos, Stefanos A.; Metzeler, Klaus H.; Herold, Tobias; Ksienzyk, Bianka; Braeundl, Kathrin; Tschuri, Sebastian; Vosberg, Sebastian; Konstandin, Nikola P.; Wang, Christine; Hartmann, Luise; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Schneider, Stephanie; Thiede, Christian; Middeke, Jan Moritz; Stoelzel, Friedrich; Roellig, Christoph; Schetelig, Johannes; Ehninger, Gerhard; Kraemer, Alwin; Braess, Jan; Goerlich, Dennis; Sauerland, Maria Cristina; Berdel, Wolfgang E.; Woermann, Bernhard J.; Hiddemann, Wolfgang; Spiekermann, Karsten; Bohlander, Stefan K. und Greif, Philipp A.
(2020):
The clinical mutatome of core binding factor leukemia.
In: Leukemia, Bd. 34, Nr. 6: S. 1553-1562
Herold, Tobias; Jurinovic, Vindi; Arnreich, Chiara; Lipworth, Brian J.; Hellmuth, Johannes C.; Bergwelt-Baildon, Michael von; Klein, Matthias und Weinberger, Tobias
(2020):
Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19.
In: Journal of Allergy and Clinical Immunology, Bd. 146, Nr. 1: S. 128-136
2019
Jilg, Stefanie; Hauch, Richard T.; Kauschinger, Johanna; Buschhorn, Lars; Odinius, Timo O.; Dill, Veronika; Müller-Thomas, Catharina; Herold, Tobias; Prodinger, Peter M.; Schmidt, Burkhard; Hempel, Dirk; Bassermann, Florian; Peschel, Christian; Götze, Katharina S.; Hoeckendorf, Ulrike; Haferlach, Torsten und Jost, Philipp J.
(2019):
Venetoclax with azacitidine targets refractory MDS but spares healthy hematopoiesis at tailored dose.
In: Experimental Hematology & Oncology, Bd. 8, 9
Solovey, Maria; Wang, Ying; Michel, Christian; Metzeler, Klaus H.; Herold, Tobias; Goethert, Joachim R.; Ellenrieder, Volker; Hessmann, Elisabeth; Gattenloehner, Stefan; Neubauer, Andreas; Pavlinic, Dinko; Benes, Vladimir; Rupp, Oliver und Burchert, Andreas
(2019):
Nuclear factor of activated T-cells, NFATC1, governs FLT3(ITD)-driven hematopoietic stem cell transformation and a poor prognosis in AML.
In: Journal of Hematology & Oncology, Bd. 12, 72
Thoene, Silvia; Mandal, Tamoghna; Vegi, Naidu M.; Quintanilla-Martinez, Leticia; Roesler, Reinhild; Wiese, Sebastian; Metzeler, Klaus H.; Herold, Tobias; Haferlach, Torsten; Doehner, Konstanze; Doehner, Hartmut; Schwarzmüller, Luisa; Klingmüller, Ursula; Buske, Christian; Rawat, Vijay P. S. und Feuring-Buske, Michaela
(2019):
The ParaHox gene Cdx4 induces acute erythroid leukemia in mice.
In: Blood Advances, Bd. 3, Nr. 22: S. 3729-3739
Angenendt, Linus; Bormann, Eike; Pabst, Caroline; Alla, Vijay; Goerlich, Dennis; Braun, Leonie; Dohlich, Kim; Schwoeppe, Christian; Bohlander, Stefan K.; Arteaga, Maria Francisca; Wethmar, Klaus; Hartmann, Wolfgang; Angenendt, Adrian; Kessler, Torsten; Mesters, Rolf M.; Stelljes, Matthias; Rothenberg-Thurley, Maja; Spiekermann, Karsten; Hebert, Josee; Sauvageau, Guy; Valk, Peter J. M.; Loewenberg, Bob; Serve, Hubert; Müller-Tidow, Carsten; Lenz, Georg; Woermann, Bernhard J.; Sauerland, M. Christina; Hiddemann, Wolfgang; Berdel, Wolfgang E.; Krug, Utz; Metzeler, Klaus H.; Mikesch, Jan-Henrik; Herold, Tobias und Schliemann, Christoph
(2019):
The neuropeptide receptor calcitonin receptor-like (CALCRL) is a potential therapeutic target in acute myeloid leukemia.
In: Leukemia, Bd. 33, Nr. 12: S. 2830-2841
Batcha, Aarif M. N.; Bamopoulos, Stefanos A.; Kerbs, Paul; Kumar, Ashwini; Jurinovic, Vindi; Rothenberg-Thurley, Maja; Ksienzyk, Bianka; Philippou-Massier, Julia; Krebs, Stefan; Blum, Helmut; Schneider, Stephanie; Konstandin, Nikola; Bohlander, Stefan K.; Heckman, Caroline; Kontro, Mika; Hiddemann, Wolfgang; Spiekermann, Karsten; Braess, Jan; Metzeler, Klaus H.; Greif, Philipp A.; Mansmann, Ulrich und Herold, Tobias
(2019):
Allelic Imbalance of Recurrently Mutated Genes in Acute Myeloid Leukaemia.
In: Scientific Reports, Bd. 9, Nr. 11796
[PDF, 1MB]
2018
Herold, Tobias; Jurinovic, Vindi; Batcha, Aarif Mohamed Nazeer; Bamopoulos, Stefanos A.; Rothenberg-Thurley, Maja; Ksienzyk, Bianka; Hartmann, Luise; Greif, Philipp A.; Phillippou-Massier, Julia; Krebs, Stefan; Blum, Helmut; Amler, Susanne; Schneider, Stephanie; Konstandin, Nikola P.; Sauerland, Maria Cristina; Görlich, Dennis; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Tischer, Johanna; Subklewe, Marion; Bohlander, Stefan K.; Braess, Jan; Hiddemann, Wolfgang; Metzeler, Klaus H.; Mansmann, Ulrich und Spiekermann, Karsten
(März 2018):
A 29-gene and cytogenetic score for the prediction of resistance to induction treatment in acute myeloid leukemia.
In: Haematologica, Bd. 103, Nr. 3: S. 456-65
Greif, Philipp A.; Hartmann, Luise; Vosberg, Sebastian; Stief, Sophie M.; Mattes, Raphael; Hellmann, Ines; Metzeler, Klaus H.; Herold, Tobias; Bamopoulos, Stefanos A.; Kerbs, Paul; Jurinovic, Vindi; Schumacher, Daniela; Pastore, Friederike; Bräundl, Kathrin; Zellmeier, Evelyn; Ksienzyk, Bianka; Konstandin, Nikola P.; Schneider, Stephanie; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Neumann, Martin; Baldus, Claudia D.; Bohlander, Stefan K.; Wolf, Stephan; Görlich, Dennis; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Hiddemann, Wolfgang und Spiekermann, Karsten
(2018):
Evolution of Cytogenetically Normal Acute Myeloid Leukemia During Therapy and Relapse: An Exome Sequencing Study of 50 Patients.
In: Clinical Cancer Research, Bd. 24, Nr. 7: S. 1716-1726
Konstandin, Nikola P.; Pastore, Friederike; Herold, Tobias; Dufour, Annika; Rothenberg-Thurley, Maja; Hinrichsen, Tanja; Ksienzyk, Bianka; Tschuri, Sebastian; Schneider, Stephanie; Hoster, Eva; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Sauerland, Maria C.; Braess, Jan; Bohlander, Stefan K.; Klein, Hanns-Georg; Hiddemann, Wolfgang; Metzeler, Klaus H. und Spiekermann, Karsten
(2018):
Genetic heterogeneity of cytogenetically normal AML with mutations of CEBPA.
In: Blood Advances, Bd. 2, Nr. 20: S. 2724-2731
Hornung, Roman; Jurinovic, Vindi; Batcha, Aarif M. N.; Bamopoulos, Stefanos A.; Rothenberg-Thurley, Maja; Amler, Susanne; Sauerland, Maria Cristina; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Bohlander, Stefan K.; Braess, Jan; Hiddemann, Wolfgang; Lehmann, Sören; Mareschal, Sylvain; Spiekermann, Karsten; Metzeler, Klaus H.; Herold, Tobias und Boulesteix, Anne-Laure
(2018):
Mediation analysis reveals common mechanisms of RUNX1 point mutations and RUNX1/RUNX1T1 fusions influencing survival of patients with acute myeloid leukemia.
In: Scientific Reports, Bd. 8, Nr. 1: S. 1-13
[PDF, 1MB]
Rothenberg-Thurley, Maja; Amler, Susanne; Goerlich, Dennis; Köhnke, Thomas; Konstandin, Nikola P.; Schneider, Stephanie; Sauerland, Maria C.; Herold, Tobias; Hubmann, Max; Ksienzyk, Bianka; Zellmeier, Evelyn; Bohlander, Stefan K.; Subklewe, Marion; Faldum, Andreas; Hiddemann, Wolfgang; Braess, Jan; Spiekermann, Karsten und Metzeler, Klaus H.
(2018):
Persistence of pre-leukemic clones during first remission and risk of relapse in acute myeloid leukemia.
In: Leukemia, Bd. 32, Nr. 7: S. 1598-1608
Prassek, Victoria V.; Rothenberg-Thurley, Maja; Sauerland, Maria C.; Herold, Tobias; Janke, Hanna; Ksienzyk, Bianka; Konstandin, Nikola P.; Goerlich, Dennis; Krug, Utz; Faldum, Andreas; Berdel, Wolfgang E.; Wörmann, Bernhard; Braess, Jan; Schneider, Stephanie; Subklewe, Marion; Bohlander, Stefan K.; Hiddemann, Wolfgang; Spiekermann, Karsten und Metzeler, Klaus H.
(2018):
Genetics of acute myeloid leukemia in the elderly: mutation spectrum and clinical impact in intensively treated patients aged 75 years or older.
In: Haematologica, Bd. 103, Nr. 11: S. 1853-1861
[PDF, 1MB]
Stecher, Stephanie-Susanne; Beyer, Georg; Goni, Elisabetta; Tischer, Johanna; Herold, Tobias; Schulz, Christoph; op den Winkel, Mark; Stemmler, H. Joachim und Lippl, Stephanie
(2018):
Extracorporeal Membrane Oxygenation in Predominantly Leuco- and Thrombocytopenic Haematologic/Oncologic Patients with Acute Respiratory Distress Syndrome a Single-Centre Experience.
In: Oncology Research and Treatment, Bd. 41, Nr. 9: S. 539-543
Norgaard, Caroline Holm; Jakobsen, Lasse Hjort; Gentles, Andrew J.; Dybkaer, Karen; El-Galaly, Tarec Christoffer; Bodker, Julie Stove; Schmitz, Alexander; Johansen, Preben; Herold, Tobias; Spiekermann, Karsten; Brown, Jennifer R.; Klitgaard, Josephine L.; Johnsen, Hans Erik und Bogsted, Martin
(2018):
Subtype assignment of CLL based on B-cell subset associated gene signatures from normal bone marrow - A proof of concept study.
In: PLOS One 13(3), e0193249 [PDF, 2MB]
In: PLOS One 13(3), e0193249 [PDF, 2MB]
Klau, Simon; Jurinovic, Vindi; Hornung, Roman; Herold, Tobias und Boulesteix, Anne-Laure
(2018):
Priority-Lasso: a simple hierarchical approach to the prediction of clinical outcome using multi-omics data.
In: BMC Bioinformatics
:19:322
[PDF, 1MB]
Schranz, Katrin; Hubmann, Max; Harin, Egor; Vosberg, Sebastian; Herold, Tobias; Metzeler, Klaus H.; Rothenberg-Thurley, Maja; Janke, Hanna; Bräundl, Kathrin; Ksienzyk, Bianka; Batcha, Aarif M. N.; Schaaf, Sebastian; Schneider, Stephanie; Bohlander, Stefan K.; Görlich, Dennis; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Braess, Jan; Krebs, Stefan; Hiddemann, Wolfgang; Mansmann, Ulrich; Spiekermann, Karsten und Greif, Philipp A.
(2018):
Clonal heterogeneity of FLT3-ITD detected by high-throughput amplicon sequencing correlates with adverse prognosis in acute myeloid leukemia.
In: Oncotarget, Bd. 9, Nr. 53: S. 30128-30145
[PDF, 2MB]
2017
Klau, Simon; Jurinovic, Vindi; Hornung, Roman; Herold, Tobias und Boulesteix, Anne-Laure
(23. November 2017):
Priority-Lasso: a simple hierarchical approach to the prediction of clinical outcome using multi-omics data.
Department of Statistics: Technical Reports, Nr. 213
[PDF, 528kB]
Herold, Tobias und Gökbuget, Nicola
(2017):
Philadelphia-Like Acute Lymphoblastic Leukemia in Adults.
In: Current Oncology Reports, Bd. 19, Nr. 5, 31
Herold, Tobias; Schneider, S.; Metzeler, Klaus H.; Neumann, Martin; Hartmann, Luise; Roberts, Kathryn G.; Konstandin, Nikola P.; Greif, Philipp A.; Bräundl, Kathrin; Ksienzyk, Bianka; Huk, Natalia; Schneider, Irene; Zellmeier, Evelyn; Jurinovic, Vindi; Mansmann, Ulrich; Hiddemann, Wolfgang; Mullighan, Charles G.; Bohlander, Stefan K.; Spiekermann, Karsten; Hölzel, Dieter; Brüggemann, Monika; Baldus, Claudia D.; Dreyling, Martin und Gökbuget, Nicola
(2017):
Adults with Philadelphia chromosome–like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis.
In: Haematologica, Bd. 102, Nr. 1: S. 130-138
[PDF, 1MB]
Herold, Tobias; Metzeler, Klaus H.; Vosberg, Sebastian; Hartmann, Luise; Jurinovic, Vindi; Opatz, Sabrina; Konstandin, Nikola P.; Schneider, S.; Zellmeier, Evelyn; Ksienzyk, Bianka; Graf, A.; Krebs, S.; Blum, H.; Sauerland, Maria Cristina; Büchner, T.; Berdel, W. E.; Wörmann, Bernhard; Mansmann, Ulrich; Hiddemann, Wolfgang; Bohlander, Stefan K.; Spiekermann, Karsten und Greif, Philipp A.
(2017):
Acute Myeloid Leukemia with Del(9q) is Characterized by Frequent Mutations of NPM1, DNMT3A, WT1 and Low Expression of TLE4.
In: Genes, Chromosomes and Cancer, Bd. 56, Nr. 1: S. 75-86
Herold, Tobias; Jurinovic, V.; Metzeler, K. H.; Batcha, A. M. N.; Bamopoulos, S. A.; Rothenberg-Thurley, M.; Ksienzyk, B.; Hartmann, L.; Greif, P. A.; Phillippou-Massier, J.; Krebs, S.; Blum, H.; Amler, S.; Schneider, S.; Konstandin, N.; Sauerland, M. C.; Berdel, W. E.; Wörmann, B. J.; Subklewe, M.; Fiegl, M.; Bohlander, S. K.; Braess, J.; Hiddemann, W.; Mansmann, Ulrich und Spiekermann, K.
(2017):
Prediction of Primary Refractory Acute Myeloid Leukemia.
In: Annals of Hematology, Bd. 96:
S25-S25
2016
Höckendorf, Ulrike; Yabal, Monica; Herold, Tobias; Munkhbaatar, Enkhtsetseg; Rott, Stephanie; Jilg, Stefanie; Kauschinger, Johanna; Magnani, Giovanni; Reisinger, Florian; Heuser, Michael; Kreipe, Hans; Sotlar, Karl; Engleitner, Thomas; Rad, Roland; Weichert, Wilko; Peschel, Christian; Ruland, Jürgen; Heikenwalder, Mathias; Spiekermann, Karsten; Slotta-Huspenina, Julia; Groß, Olaf und Jost, Philipp J.
(2016):
RIPK3 Restricts Myeloid Leukemogenesis by Promoting Cell Death and Differentiation of Leukemia Initiating Cells.
In: Cancer Cell, Bd. 30, Nr. 1: S. 75-91
Metzeler, Klaus H.; Herold, Tobias; Rothenberg-Thurley, Maja; Amler, Susanne; Sauerland, Maria C.; Görlich, Dennis; Schneider, Stephanie; Konstandin, Nikola P.; Dufour, Annika; Bräundl, Kathrin; Ksienzyk, Bianka; Zellmeier, Evelyn; Hartmann, Luise; Greif, Philipp A.; Fiegl, Michael; Subklewe, Marion; Bohlander, Stefan K.; Krug, Utz; Faldum, Andreas; Berdel, Wolfgang E.; Wörmann, Bernhard; Büchner, Thomas; Hiddemann, Wolfgang; Braess, Jan und Spiekermann, Karsten
(2016):
Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia.
In: Blood, Bd. 128, Nr. 5: S. 686-698
Pabst, Caroline; Bergeron, Anne; Lavallée, Vincent-Philippe; Yeh, Jonathan; Gendron, Patrick; Norddahl, Gudmundur L.; Krosl, Jana; Boivin, Isabel; Deneault, Eric; Simard, Jessica; Imren, Suzan; Boucher, Geneviève; Eppert, Kolja; Herold, Tobias; Bohlander, Stefan K.; Humphries, Keith; Lemieux, Sebastien; Hebert, Josée; Sauvageau, Guy und Barabé, Frédéric
(2016):
GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo.
In: Blood, Bd. 127, Nr. 16: S. 2018-2027
Jiang, Xi; Bugno, Jason; Hu, Chao; Yang, Yang; Herold, Tobias; Qi, Jun; Chen, Ping; Gurbuxani, Sandeep; Arnovitz, Stephen; Strong, Jennifer; Ferchen, Kyle; Ulrich, Bryan; Weng, Hengyou; Wang, Yungui; Huang, Hao; Li, Shenglai; Neilly, Mary Beth; Larson, Richard A.; Le Beau, Michelle M.; Bohlander, Stefan K.; Jin, Jie; Li, Zejuan; Bradner, James E.; Hong, Seungpyo und Chen, Jianjun
(2016):
Eradication of Acute Myeloid Leukemia with FLT3 Ligand-Targeted miR-150 Nanoparticles.
In: Cancer Research, Bd. 76, Nr. 15: S. 4470-4480
Ng, Stanley W. K.; Mitchell, Amanda; Kennedy, James A.; Chen, Weihsu C.; McLeod, Jessica; Ibrahimova, Narmin; Arruda, Andrea; Popescu, Andreea; Gupta, Vikas; Schimmer, Aaron D.; Schuh, Andre C.; Yee, Karen W.; Bullinger, Lars; Herold, Tobias; Görlich, Dennis; Büchner, Thomas; Hiddemann, Wolfgang; Berdel, Wolfgang E.; Wörmann, Bernhard; Cheok, Meyling; Preudhomme, Claude; Dombret, Hervé; Metzeler, Klaus; Buske, Christian; Löwenberg, Bob; Valk, Peter J. M.; Zandstra, Peter W.; Minden, Mark D. .; Dick, John E. und Wang, Jean C. Y.
(2016):
A 17-gene stemness score for rapid determination of risk in acute leukaemia.
In: Nature, Bd. 540, Nr. 7633: S. 433-437
Niavarani, Ahmadreza; Herold, Tobias; Reyal, Yasmin; Sauerland, Maria C.; Buchner, Thomas; Hiddemann, Wolfgang; Bohlander, Stefan K.; Valk, Peter J. M. und Bonnet, Dominique
(2016):
A 4-gene expression score associated with high levels of Wilms Tumor-1 (WT1) expression is an adverse prognostic factor in acute myeloid leukaemia.
In: British Journal of Haematology, Bd. 172, Nr. 3: S. 401-411
Jiang, Xi; Hu, Chao; Arnovitz, Stephen; Bugno, Jason; Yu, Miao; Zuo, Zhixiang; Chen, Ping; Huang, Hao; Ulrich, Bryan; Gurbuxani, Sandeep; Weng, Hengyou; Strong, Jennifer; Wang, Yungui; Li, Yuanyuan; Salat, Justin; Li, Shenglai; Elkahloun, Abdel G.; Yang, Yang; Neilly, Mary Beth; Larson, Richard A.; Le Beau, Michelle M.; Herold, Tobias; Bohlander, Stefan K.; Liu, Paul P.; Zhang, Jiwang; Li, Zejuan; He, Chuan; Jin, Jie; Hong, Seungpyo und Chen, Jianjun
(2016):
miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia.
In: Nature Communications, Bd. 7, 11452
[PDF, 3MB]
Hartmann, Luise; Dutta, Sayantanee; Opatz, Sabrina; Vosberg, Sebastian; Reiter, Katrin; Leubolt, Georg; Metzeler, Klaus H.; Herold, Tobias; Bamopoulos, Stefanos A.; Bräundl, Kathrin; Zellmeier, Evelyn; Ksienzyk, Bianka; Konstandin, Nikola P.; Schneider, Stephanie; Hopfner, Karl-Peter; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Middeke, Jan Moritz; Stölzel, Friedrich; Thiede, Christian; Wolf, Stephan; Bohlander, Stefan K.; Preiss, Caroline; Chen-Wichmann, Linping; Wichmann, Christian; Sauerland, Maria Cristina; Büchner, Thomas; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Braess, Jan; Hiddemann, Wolfgang; Spiekermann, Karsten und Greif, Philipp A.
(2016):
ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation.
In: Nature Communications, Bd. 7, 11733
[PDF, 1MB]
Laverdière, Isabelle; Boileau, Meaghan; Herold, Tobias; Rak, Janusz; Berdel, Wolfgang E.; Wörmann, Bernhard; Hiddemann, Wolfgang; Spiekermann, Karsten; Bohlander, Stefan K. und Eppert, Kolja
(2016):
Complement cascade gene expression defines novel prognostic subgroups of acute myeloid leukemia.
In: Experimental Hematology, Bd. 44, Nr. 11: S. 1039-1043
Vosberg, Sebastian; Herold, Tobias; Hartmann, Luise; Neumann, Martin; Opatz, Sabrina; Metzeler, Klaus H.; Schneider, S.; Graf, A.; Krebs, S.; Blum, H.; Baldus, Claudia D.; Hiddemann, Wolfgang; Spiekermann, Karsten; Bohlander, Stefan K.; Mansmann, Ulrich und Greif, Philipp A.
(2016):
Close Correlation of Copy Number Aberrations Detected by Close correlation of copy number aberrations detected by next-generation sequencing with results from routine cytogenetics in acute myeloid leukemia.
In: Genes, Chromosomes and Cancer, Bd. 55, Nr. 7: S. 553-567
2015
Kuett, Alexander; Rieger, Christina; Perathoner, Deborah; Herold, Tobias; Wagner, Michaela; Sironi, Silvia; Sotlar, Karl; Horny, Hans-Peter; Deniffel, Christian; Drolle, Heidrun und Fiegl, Michael
(2015):
IL-8 as mediator in the microenvironment-leukaemia network in acute myeloid leukaemia.
In: Scientific Reports, Bd. 5, 18411
[PDF, 1MB]
2014
De Bin, Riccardo; Herold, Tobias und Boulesteix, Anne-Laure
(18. Februar 2014):
Added predictive value of omics data: specific
issues related to validation illustrated by two
case studies.
Department of Statistics: Technical Reports, Nr. 154
[PDF, 542kB]
De Bin, Riccardo; Herold, Tobias und Boulesteix, Anne-Laure
(2014):
Added predictive value of omics data: specific issues related to validation illustrated by two case studies.
In: BMC Medical Research Methodology
14:117
[PDF, 765kB]
Janke, Hanna; Pastore, Friederike; Schumacher, Daniela; Herold, Tobias; Hopfner, Karl-Peter; Schneider, Stephanie; Berdel, Wolfgang E.; Büchner, Thomas; Woermann, Bernhard J.; Subklewe, Marion; Bohlander, Stefan K.; Hiddemann, Wolfgang; Spiekermann, Karsten und Polzer, Harald
(2014):
Activating FLT3 Mutants Show Distinct Gain-of-Function Phenotypes In Vitro and a Characteristic Signaling Pathway Profile Associated with Prognosis in Acute Myeloid Leukemia.
In: PLOS ONE 9(3), e89560 [PDF, 2MB]
In: PLOS ONE 9(3), e89560 [PDF, 2MB]
2013
Li, Z.; Herold, Tobias; He, C.; Valk, P. J.; Chen, P.; Jurinovic, Vindi; Mansmann, Ulrich; Radmacher, M. D.; Maharry, K. S.; Sun, M.; Yang, X.; Huang, H.; Jiang, X.; Sauerland, M. C.; Büchner, T.; Hiddemann, Wolfgang; Elkahloun, A.; Neilly, M. B.; Zhang, Y.; Larson, R. A.; Le Beau, M. M.; Caligiuri, M. A.; Dohner, K.; Bullinger, L.; Liu, P. P.; Delwel, R.; Marcucci, G.; Lowenberg, B.; Bloomfield, C. D.; Rowley, J. D.; Bohlander, Stefan K. und Chen, J.
(2013):
Identification of a 24-Gene Prognostic Signature That Improves the European LeukemiaNet Risk Classification of Acute Myeloid Leukemia: An International Collaborative Study.
In: Journal of Clinical Oncology, Bd. 31, Nr. 9: S. 1172-1181
2012
Greif, Philipp A.; Dufour, A.; Konstandin, Nikola P.; Ksienzyk, Bianka; Zellmeier, Evelyn; Tizazu, B.; Sturm, J.; Benthaus, T.; Herold, Tobias; Yaghmaie, M.; Dorge, P.; Hopfner, K. P.; Hauser, A.; Graf, A.; Krebs, S.; Blum, H.; Kakadia, P. M.; Schneider, S.; Hoster, Eva; Schneider, F.; Stanulla, M.; Braess, J.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Hiddemann, Wolfgang; Spiekermann, Karsten und Bohlander, Stefan K.
(2012):
GATA2 zinc finger 1 mutations associated with biallelic CEBPA mutations define a unique genetic entity of acute myeloid leukemia.
In: Blood, Bd. 120, Nr. 2: S. 395-403
Herold, Tobias; Mulaw, M. A.; Jurinovic, Vindi; Seiler, T.; Metzeler, Klaus H.; Dufour, A.; Schneider, S.; Kakadia, P. M.; Spiekermann, Karsten; Mansmann, Ulrich; Hiddemann, Wolfgang; Buske, C.; Dreyling, Martin und Bohlander, Stefan K.
(2012):
High expression of MZB1 predicts adverse prognosis in chronic lymphocytic leukemia, follicular lymphoma and diffuse large B-cell lymphoma and is associated with a unique gene expression signature.
In: Leukemia & Lymphoma, Bd. 54, Nr. 8: S. 1652-1657
2011
Herold, Tobias; Jurinovic, Vindi; Metzeler, Klaus H.; Boulesteix, Anne-Laure; Bergmann, M.; Seiler, T.; Mulaw, M.; Thoene, S.; Dufour, A.; Pasalic, Z.; Schmidberger, Markus; Schmidt, M.; Schneider, S.; Kakadia, P. M.; Feuring-Buske, M.; Braess, J.; Spiekermann, Karsten; Mansmann, Ulrich; Hiddemann, Wolfgang; Buske, C. und Bohlander, Stefan K.
(2011):
An eight-gene expression signature for the prediction of survival and time to treatment in chronic lymphocytic leukemia.
In: Leukemia, Bd. 25, Nr. 10: S. 1639-1645
Herold, Tobias; Jurinovic, Vindi; Mulaw, M.; Seiler, T.; Dufour, A.; Schneider, S.; Kakadia, P. M.; Feuring-Buske, M.; Braess, J.; Spiekermann, Karsten; Mansmann, Ulrich; Hiddemann, Wolfgang; Buske, C. und Bohlander, Stefan K.
(2011):
Expression analysis of genes located in the minimally deleted regions of 13q14 and 11q22-23 in chronic lymphocytic leukemia-unexpected expression pattern of the RHO GTPase activator ARHGAP20.
In: Genes, Chromosomes and Cancer, Bd. 50, Nr. 7: S. 546-558
2009
Thoene, S.; Rawat, V. P.; Heilmeier, B.; Hoster, Eva; Metzeler, Klaus H.; Herold, Tobias; Hiddemann, Wolfgang; Gökbuget, Nicola; Hoelzer, D.; Bohlander, Stefan K.; Feuring-Buske, M. und Buske, C.
(2009):
The homeobox gene CDX2 is aberrantly expressed and associated with an inferior prognosis in patients with acute lymphoblastic leukemia.
In: Leukemia, Bd. 23, Nr. 4: S. 649-655