Anzahl der Publikationen: 25
2022
Brech, Dorothee; Herbstritt, Anna S.; Diederich, Sarah; Straub, Tobias; Kokolakis, Evangelos; Irmler, Martin; Beckers, Johannes; Buettner, Florian A.; Schaeffeler, Elke; Winter, Stefan; Schwab, Matthias; Nelson, Peter J. und Noessner, Elfriede
(2022):
Dendritic Cells or Macrophages? The Microenvironment of Human Clear Cell Renal Cell Carcinoma Imprints a Mosaic Myeloid Subtype Associated with Patient Survival.
In: Cells, Bd. 11, Nr. 20, 3289
Sanchez-Gonzalez, Rosario; Koupourtidou, Christina; Lepko, Tjasa; Zambusi, Alessandro; Novoselc, Klara Tereza; Durovic, Tamara; Aschenbroich, Sven; Schwarz, Veronika; Breunig, Christopher T.; Straka, Hans; Huttner, Hagen B.; Irmler, Martin; Beckers, Johannes; Wurst, Wolfgang; Zwergal, Andreas; Schauer, Tamas; Straub, Tobias; Czopka, Tim; Trümbach, Dietrich; Götz, Magdalena; Stricker, Stefan H. und Ninkovic, Jovica
(2022):
Innate Immune Pathways Promote Oligodendrocyte Progenitor Cell Recruitment to the Injury Site in Adult Zebrafish Brain.
In: Cells, Bd. 11, Nr. 3, 520
[PDF, 9MB]
2021
Trefzer, Anne; Kadam, Pallavi; Wang, Shu-Hung; Pennavaria, Stefanie; Lober, Benedikt; Akcabozan, Batuhan; Kranich, Jan; Brocker, Thomas; Nakano, Naoko; Irmler, Martin; Beckers, Johannes; Straub, Tobias und Obst, Reinhard
(2021):
Dynamic adoption of anergy by antigen-exhausted CD4(+) T cells.
In: Cell Reports, Bd. 34, Nr. 6, 108748
Giroud, Maude; Tsokanos, Foivos-Filippos; Caratti, Giorgio; Kotschi, Stefan; Khani, Sajjad; Jouffe, Celine; Vogl, Elena S.; Irmler, Martin; Glantschnig, Christina; Gil-Lozano, Manuel; Hass, Daniela; Khan, Asrar Ali; Garcia, Marcos Rios; Mattijssen, Frits; Maida, Adriano; Tews, Daniel; Fischer-Posovszky, Pamela; Feuchtinger, Annette; Virtanen, Kirsi A.; Beckers, Johannes; Wabitsch, Martin; Uhlenhaut, Henriette; Bluher, Matthias; Tuckermann, Jan; Scheideler, Marcel; Bartelt, Alexander und Herzig, Stephan
(2021):
HAND2 is a novel obesity-linked adipogenic transcription factor regulated by glucocorticoid signalling.
In: Diabetologia, Bd. 64, Nr. 8: S. 1850-1865
Gerckens, Michael; Schorpp, Kenji; Pelizza, Francesco; Woegrath, Melanie; Reichau, Kora; Ma, Huilong; Dworsky, Armando-Marco; Sengupta, Arunima; Stoleriu, Mircea Gabriel; Heinzelmann, Katharina; Merl-Pham, Juliane; Irmler, Martin; Alsafadi, Hani N.; Trenkenschuh, Eduard; Sarnova, Lenka; Jirouskova, Marketa; Friess, Wolfgang; Hauck, Stefanie M.; Beckers, Johannes; Kneidinger, Nikolaus; Behr, Jürgen; Hilgendorff, Anne; Hadian, Kamyar; Lindner, Michael; Koenigshoff, Melanie; Eickelberg, Oliver; Gregor, Martin; Plettenburg, Oliver; Yildirim, Ali Oender und Burgstaller, Gerald
(2021):
Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics.
In: Science Advances, Bd. 7, Nr. 52, eabb3673
Dreher, Simon I.; Hoeckele, Selina; Huypens, Peter; Irmler, Martin; Hoffmann, Christoph; Jeske, Tim; Hastreiter, Maximilian; Moller, Anja; Birkenfeld, Andreas L.; Haering, Hans-Ulrich; Peter, Andreas; Beckers, Johannes; Hrabe de Angelis, Martin und Weigert, Cora
(2021):
TGF-beta Induction of miR-143/145 Is Associated to Exercise Response by Influencing Differentiation and Insulin Signaling Molecules in Human Skeletal Muscle.
In: Cells, Bd. 10, Nr. 12, 3443
Boettcher, Anika; Buettner, Maren; Tritschler, Sophie; Sterr, Michael; Aliluev, Alexandra; Oppenlaender, Lena; Burtscher, Ingo; Sass, Steffen; Irmler, Martin; Beckers, Johannes; Ziegenhain, Christoph; Enard, Wolfgang; Schamberger, Andrea C.; Verhamme, Fien M.; Eickelberg, Oliver; Theis, Fabian J. und Lickert, Heiko
(2021):
Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates.
In: Nature Cell Biology, Bd. 23, Nr. 1
2020
Schriever, Sonja C. ORCID: https://orcid.org/0000-0001-5461-3214; Kabra, Dhiraj G.; Pfuhlmann, Katrin; Baumann, Peter ORCID: https://orcid.org/0000-0002-7009-1580; Baumgart, Emily V.; Nagler, Joachim; Seebacher, Fabian ORCID: https://orcid.org/0000-0003-2211-8723; Harrison, Luke; Irmler, Martin ORCID: https://orcid.org/0000-0003-3169-479X; Kullmann, Stephanie; Corrêa-da-Silva, Felipe ORCID: https://orcid.org/0000-0002-7333-367X; Giesert, Florian; Jain, Ruchi; Schug, Hannah; Castel, Julien; Martinez, Sarah; Wu, Moya; Häring, Hans-Ulrich; de Angelis, Martin Hrabe ORCID: https://orcid.org/0000-0002-7898-2353; Beckers, Johannes ORCID: https://orcid.org/0000-0001-7874-3822; Müller, Timo D. ORCID: https://orcid.org/0000-0002-0624-9339; Stemmer, Kerstin; Wurst, Wolfgang; Rozman, Jan ORCID: https://orcid.org/0000-0002-8035-8904; Nogueiras, Ruben; De Angelis, Meri; Molkentin, Jeffery D. ORCID: https://orcid.org/0000-0002-3558-6529; Krahmer, Natalie; Yi, Chun-Xia ORCID: https://orcid.org/0000-0003-1184-4615; Schmidt, Mathias V.; Luquet, Serge; Heni, Martin ORCID: https://orcid.org/0000-0002-8462-3832; Tschöp, Matthias H. und Pfluger, Paul T. ORCID: https://orcid.org/0000-0002-8118-7588
(2020):
Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity.
In: Journal of Clinical Investigation, Bd. 130, Nr. 11: S. 6093-6108
Nouri, Parivash; Goetz, Sebastian; Rauser, Benedict; Irmler, Martin; Peng, Changgeng; Truembach, Dietrich; Kempny, Christian; Lechermeier, Carina G.; Bryniok, Agnes; Dlugos, Andrea; Euchner, Ellen; Beckers, Johannes; Brodski, Claude; Kluemper, Claudia; Wurst, Wolfgang und Prakash, Nilima
(2020):
Dose-Dependent and Subset-Specific Regulation of Midbrain Dopaminergic Neuron Differentiation by LEF1-Mediated WNT1/b-Catenin Signaling.
In: Frontiers in Cell and Developmental Biology, Bd. 8, 587778
[PDF, 13MB]
Ruschil, Christoph; Gabernet, Gisela; Lepennetier, Gildas; Heumos, Simon; Kaminski, Miriam; Hracsko, Zsuzsanna; Irmler, Martin; Beckers, Johannes; Ziemann, Ulf; Nahnsen, Sven; Owens, Gregory P.; Bennett, Jeffrey L.; Hemmer, Bernhard und Kowarik, Markus C.
(2020):
Specific Induction of Double Negative B Cells During Protective and Pathogenic Immune Responses.
In: Frontiers in Immunology, Bd. 11, 606338
[PDF, 2MB]
Chhabra, Nirav Florian; Amarie, Oana Veronica; Wu, Moya; Amend, Anna-Lena; Rubey, Marina; Gradinger, Daniel; Irmler, Martin; Beckers, Johannes; Rathkolb, Birgit; Wolf, Eckhard; Feuchtinger, Annette; Huypens, Peter; Teperino, Raffaele; Rozman, Jan; Przemeck, Gerhard K. H. und Hrabe de Angelis, Martin
(2020):
PAX6 mutation alters circadian rhythm and beta cell function in mice without affecting glucose tolerance.
In: Communications Biology, Bd. 3, Nr. 1, 628
2019
Wang, Xianming; Sterr, Michael; Burtscher, Ingo; Böttcher, Anika; Beckenbauer, Julia; Siehler, Johanna; Meitinger, Thomas; Haering, Hans-Ulrich; Staiger, Harald; Cernilogar, Filippo M.; Schotta, Gunnar; Irmler, Martin; Beckers, Johannes; Wright, Christopher V. E.; Bakhti, Mostafa und Lickert, Heiko
(2019):
Point mutations in the PDX1 transactivation domain impair human beta-cell development and function.
In: Molecular Metabolism, Bd. 24: S. 80-97
Vetrivel, Sharmilee; Tiso, Natascia; Kuegler, Andrea; Irmler, Martin; Horsch, Marion; Beckers, Johannes; Hladik, Daniela; Giesert, Florian; Gailus-Durner, Valerie; Fuchs, Helmut; Sabrautzki, Sibylle; Angelis, Martin Hrabe de; Graw, Jochen; Adler, Thure; Treise, Irina; Busch, Dirk H.; Aguilar-Pimentel, Antonio; Ollert, Markus; Götz, Alexander; Amarie, Oana; Stoeger, Tobias; Schulz, Holger; Becker, Lore; Klopstock, Thomas; Schrewe, Anja; Spielmann, Nadine; Bekeredjian, Raffi; Garrett, Lillian; Hoelter, Sabine M.; Zimprich, Annemarie; Wurst, Wolfgang; Mayer-Kuckuk, Philipp; Hans, Wolfgang; Rozman, Jan; Klingenspor, Martin; Neff, Frauke; Silva-Buttkus, Patricia da; Calzada-Wack, Julia; Racz, Ildiko; Zimmer, Andreas; Rathkolb, Birgit; Wolf, Eckhard; Prehn, Cornelia; Adamski, Jerzy; Oestereicher, Manuela; Miller, Gregor; Steinkamp, Ralph; Lengger, Christoph; Maier, Holger; Stoeger, Claudia und Leuchtenberger, Stefanie
(2019):
Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia.
In: Experimental Eye Research, Bd. 188, UNSP 107632
[PDF, 7MB]
2018
Di Giaimo, Rossella; Durovic, Tamara; Barquin, Pablo; Kociaj, Anita; Lepko, Tjasa; Aschenbroich, Sven; Breunig, Christopher T.; Irmler, Martin; Cernilogar, Filippo M.; Schotta, Gunnar; Barbosa, Joana S.; Trümbach, Dietrich; Baumgart, Emily Violette; Neuner, Andrea M.; Beckers, Johannes; Wurst, Wolfgang; Stricker, Stefan H. und Ninkovic, Jovica
(2018):
The Aryl Hydrocarbon Receptor Pathway Defines the Time Frame for Restorative Neurogenesis.
In: Cell Reports, Bd. 25, Nr. 12: S. 3241-3251
[PDF, 4MB]
Dehmel, Stefan; Nathan, Petra; Bartel, Sabine; El-Merhie, Natalia; Scherb, Hagen; Milger, Katrin; John-Schuster, Gerrit; Yildirim, Ali Oender; Hylkema, Machteld; Irmler, Martin; Beckers, Johannes; Schaub, Bianca; Eickelberg, Oliver und Krauss-Etschmann, Susanne
(2018):
Intrauterine smoke exposure deregulates lung function, pulmonary transcriptomes, and in particular insulin-like growth factor (IGF)-1 in a sex-specific manner.
In: Scientific Reports, Bd. 8, 7547
[PDF, 2MB]
Heppt, Markus V.; Wang, Joshua X.; Hristova, Denitsa M.; Wei, Zhi; Li, Ling; Evans, Brianna; Beqiri, Marilda; Zaman, Samir; Zhang, Jie; Irmler, Martin; Berking, Carola; Besch, Robert; Beckers, Johannes; Rauscher, Frank J.; Sturm, Rick A.; Fisher, David E.; Herlyn, Meenhard und Fukunaga-Kalabis, Mizuho
(2018):
MSX1-Induced Neural Crest-Like Reprogramming Promotes Melanoma Progression.
In: Journal of Investigative Dermatology, Bd. 138, Nr. 1: S. 141-149
Fuchs, Helmut; Aguilar-Pimentel, Juan Antonio; Amarie, Oana V.; Becker, Lore; Calzada-Wack, Julia; Cho, Yi-Li; Garrett, Lillian; Hölter, Sabine M.; Irmler, Martin; Kistler, Martin; Kraiger, Markus; Mayer-Kuckuk, Philipp; Moreth, Kristin; Rathkolb, Birgit; Rozman, Jan; Silva Buttkus, Patricia da; Treise, Irina; Zimprich, Annemarie; Gampe, Kristine; Hutterer, Christine; Stoeger, Claudia; Leuchtenberger, Stefanie; Maier, Holger; Miller, Manuel; Scheideler, Angelika; Wu, Moya; Beckers, Johannes; Bekeredjian, Raffi; Brielmeier, Markus; Busch, Dirk H.; Klingenspor, Martin; Klopstock, Thomas; Ollert, Markus; Schmidt-Weber, Carsten; Stoeger, Tobias; Wolf, Eckhard; Wurst, Wolfgang; Yildirim, Ali Oender; Zimmer, Andreas; Gailus-Durner, Valerie und Hrabe de Angelis, Martin
(2018):
Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.
In: Behavioural Brain Research, Bd. 352: S. 187-196
2017
Sattler, Christine; Moritz, Franco; Chen, Shanze; Steer, Beatrix; Kutschke, David; Irmler, Martin; Beckers, Johannes; Eickelberg, Oliver; Schmitt-Kopplin, Philippe; Adler, Heiko und Stoeger, Tobias
(2017):
Nanoparticle exposure reactivates latent herpesvirus and restores a signature of acute infection.
In: Particle and Fibre Toxicology
14:2
[PDF, 8MB]
Milger, Katrin; Yu, Yingyan; Brudy, Eva; Irmler, Martin; Skapenko, Alla; Mayinger, Michael; Lehmann, Mareike; Beckers, Johannes; Reichenberger, Frank; Behr, Jürgen; Eickelberg, Oliver; Königshoff, Melanie und Krauss-Etschmann, Susanne
(2017):
Pulmonary CCR2(+)CD4(+) T cells are immune regulatory and attenuate lung fibrosis development.
In: Thorax, Bd. 72, Nr. 11: S. 1007-1020
[PDF, 9MB]
Kästle, Marc; Bartel, Sabine; Geillinger-Kästle, Kerstin; Irmler, Martin; Beckers, Johannes; Ryffel, Bernhard; Eickelberg, Oliver und Krauss-Etschmann, Susanne
(2017):
microRNA cluster 106a similar to 363 is involved in T helper 17 cell differentiation.
In: Immunology, Bd. 152, Nr. 3: S. 402-413
Altmae, Signe; Segura, Maria T.; Esteban, Francisco J.; Bartel, Sabine; Brandi, Pilar; Irmler, Martin; Beckers, Johannes; Demmelmair, Hans; Lopez-Sabater, Carmen; Koletzko, Berthold; Krauss-Etschmann, Susanne und Campoy, Cristina
(2017):
Maternal Pre-Pregnancy Obesity Is Associated with Altered Placental Transcriptome.
In: PLOS ONE
12(1), e0169223
[PDF, 2MB]
2016
Franko, Andras; Huypens, Peter; Neschen, Susanne; Irmler, Martin; Rozman, Jan; Rathkolb, Birgit; Neff, Frauke; Prehn, Cornelia; Dubois, Guillaume; Baumann, Martina; Massinger, Rebecca; Gradinger, Daniel; Przemeck, Gerhard K. H.; Repp, Birgit; Aichler, Michaela; Feuchtinger, Annette; Schommers, Philipp; Stöhr, Oliver; Sanchez-Lasheras, Carmen; Adamski, Jerzy; Peter, Andreas; Prokisch, Holger; Beckers, Johannes; Walch, Axel K.; Fuchs, Helmut; Wolf, Eckhard; Schubert, Markus; Wiesner, Rudolf J. und de Angelis, Martin Hrabe
(2016):
Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice.
In: Diabetes, Bd. 65, Nr. 9: S. 2540-2552
Gascón, Sergio; Murenu, Elisa; Masserdotti, Giacomo; Ortega, Felipe; Russo, Gianluca L.; Petrik, David; Deshpande, Aditi; Heinrich, Christophe; Karow, Marisa; Robertson, Stephen P.; Schroeder, Timm; Beckers, Johannes; Irmler, Martin; Berndt, Carsten; Angeli, José P. Friedmann; Conrad, Marcus; Berninger, Benedikt und Götz, Magdalena
(2016):
Identification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogramming.
In: Cell Stem Cell, Bd. 18, Nr. 3: S. 396-409
2015
Oehrle, Bettina; Burgstaller, Gerald; Irmler, Martin; Dehmel, Stefan; Gruen, Jessica; Hwang, Tiffany; Krauss-Etschmann, Susanne; Beckers, Johannes; Meiners, Silke und Eickelberg, Oliver
(2015):
Validated prediction of pro-invasive growth factors using a transcriptome-wide invasion signature derived from a complex 3D invasion assay.
In: Scientific Reports, Bd. 5, 12673
[PDF, 1MB]
Schmidt, Johanna M.; Panzilius, Elena; Bartsch, Harald S.; Irmler, Martin; Beckers, Johannes; Kari, Vijayalakshmi; Linnemann, Jelena R.; Dragoi, Diana; Hirschi, Benjamin; Kloos, Uwe J.; Sass, Steffen; Theis, Fabian; Kahlert, Steffen; Johnsen, Steven A.; Sotlar, Karl und Scheel, Christina H.
(2015):
Stem-Cell-like Properties and Epithelial Plasticity Arise as Stable Traits after Transient Twist1 Activation.
In: Cell Reports, Bd. 10, Nr. 2: S. 131-139
[PDF, 3MB]
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