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Anzahl der Publikationen: 49
Zeitschriftenartikel
Gottschlich, Adrian; Thomas, Moritz; Gruenmeier, Ruth; Lesch, Stefanie; Rohrbacher, Lisa; Igl, Veronika; Briukhovetska, Daria; Benmebarek, Mohamed-Reda; Vick, Binje; Dede, Sertac; Mueller, Katharina; Xu, Tao; Dhoqina, Dario; Maerkl, Florian; Robinson, Sophie; Sendelhofert, Andrea; Schulz, Heiko; Umut, Oeykue; Kavaka, Vladyslav; Tsiverioti, Christina Angeliki; Carlini, Emanuele; Nandi, Sayantan; Strzalkowski, Thaddaeus; Lorenzini, Theo; Stock, Sophia; Mueller, Philipp Jie; Doerr, Janina; Seifert, Matthias; Cadilha, Bruno L.; Brabenec, Ruben; Roeder, Natalie; Rataj, Felicitas; Nueesch, Manuel; Modemann, Franziska; Wellbrock, Jasmin; Fiedler, Walter; Kellner, Christian; Beltran, Eduardo; Herold, Tobias; Paquet, Dominik; Jeremias, Irmela; von Baumgarten, Louisa; Endres, Stefan; Subklewe, Marion; Marr, Carsten und Kobold, Sebastian
(2023):
Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia.
In: Nature Biotechnology, Bd. 41, Nr. 11:
1618-+
[PDF, 7MB]
Janjic, Aleksandar; Wange, Lucas E.; Bagnoli, Johannes W.; Geuder, Johanna; Nguyen, Phong; Richter, Daniel; Vieth, Beate; Vick, Binje; Jeremias, Irmela; Ziegenhain, Christoph; Hellmann, Ines und Enard, Wolfgang
(31. März 2022):
Prime-seq, efficient and powerful bulk RNA sequencing.
In: Genome Biology, Bd. 23
[PDF, 2MB]
Carlet, Michela; Schmelz, Karin; Vergalli, Jenny; Herold, Tobias; Senft, Daniela; Jurinovic, Vindi; Hoffmann, Thomas; Proba, Jutta; Weichert, Nina; Junghanss, Christian; Roth, Mareike; Eschenburg, Georg; Barz, Malwine; Henze, Guenter; Eckert, Cornelia; Eggert, Angelika; Zuber, Johannes; Hundsdoerfer, Patrick und Jeremias, Irmela
(2022):
X-linked inhibitor of apoptosis protein represents a promising therapeutic target for relapsed/refractory ALL.
In: EMBO Molecular Medicine, Bd. 15, Nr. 1, e14557
Janssen, Maike; Schmidt, Christina; Bruch, Peter-Martin; Blank, Maximilian F.; Rohde, Christian; Waclawiczek, Alexander; Heid, Daniel; Renders, Simon; Goellner, Stefanie; Vierbaum, Lisa; Besenbeck, Birgit; Herbst, Sophie A.; Knoll, Mareike; Kolb, Carolin; Przybylla, Adriana; Weidenauer, Katharina; Ludwig, Anne Kathrin; Fabre, Margarete; Gu, Muxin; Schlenk, Richard F.; Stoelzel, Friedrich; Bornhaeuser, Martin; Roellig, Christoph; Platzbecker, Uwe; Baldus, Claudia; Serve, Hubert; Sauer, Tim; Raffel, Simon; Pabst, Caroline; Vassiliou, George; Vick, Binje; Jeremias, Irmela; Trumpp, Andreas; Krijgsveld, Jeroen; Mueller-Tidow, Carsten und Dietrich, Sascha
(2022):
Venetoclax synergizes with gilteritinib in FLT3 wild-type high-risk acute myeloid leukemia by suppressing MCL-1.
In: Blood, Bd. 140, Nr. 24: S. 2594-2610
Wirth, Anna-Katharina; Wange, Lucas; Vosberg, Sebastian; Henrich, Kai-Oliver; Rausch, Christian; Oezdemir, Erbey; Zeller, Christina M.; Richter, Daniel; Feuchtinger, Tobias; Kaller, Markus; Hermeking, Heiko; Greif, Philipp A.; Senft, Daniela; Jurinovic, Vindi; Bahrami, Ehsan; Jayavelu, Ashok Kumar; Westermann, Frank; Mann, Matthias; Enard, Wolfgang; Herold, Tobias und Jeremias, Irmela
(2022):
In vivo PDX CRISPR/Cas9 screens reveal mutual therapeutic targets to overcome heterogeneous acquired chemo-resistance.
In: Leukemia, Bd. 36: S. 2863-2874
Koschade, Sebastian E.; Klann, Kevin; Shaid, Shabnam; Vick, Binje; Stratmann, Jan A.; Thölken, Marlyn; Meyer, Laura M.; Duy Nguyen, The; Campe, Julia; Moser, Laura M.; Hock, Susanna; Baker, Fatima; Meyer, Christian T.; Wempe, Frank; Serve, Hubert; Ullrich, Evelyn; Jeremias, Irmela; Muench, Christian und Brandts, Christian H.
(2022):
Translatome proteomics identifies autophagy as a resistance mechanism to on-target FLT3 inhibitors in acute myeloid leukemia.
In: Leukemia, Bd. 36, Nr. 10: S. 2396-2407
Philipp, Nora; Kazerani, Maryam; Nicholls, Alyssa; Vick, Binje; Wulf, Jan; Straub, Tobias; Scheurer, Michaela; Muth, Amelie; Hänel, Gerulf; Nixdorf, Daniel; Sponheimer, Monika; Ohlmeyer, Malte; Lacher, Sonja M.; Brauchle, Bettina; Marcinek, Anetta; Rohrbacher, Lisa; Leutbecher, Alexandra; Rejeski, Kai; Weigert, Oliver; Bergwelt-Baildon, Michael von; Theurich, Sebastian; Kischel, Roman; Jeremias, Irmela; Bücklein, Veit und Subklewe, Marion
(2022):
T-cell exhaustion induced by continuous bispecific molecule exposure is ameliorated by treatment-free intervals.
In: Blood, Bd. 140, Nr. 10: S. 1104-1118
Zanetti, Samanta Romina; Velasco-Hernandez, Talia; Gutierrez-Aguera, Francisco; Diaz, Victor M.; Romecin, Paola Alejandra; Roca-Ho, Heleia; Sanchez-Martinez, Diego; Tirado, Nestor; Baroni, Matteo Libero; Petazzi, Paolo; Torres-Ruiz, Raul; Molina, Oscar; Bataller, Alex; Fuster, Jose Luis; Ballerini, Paola; Juan, Manel; Jeremias, Irmela; Bueno, Clara und Menendez, Pablo
(2022):
A novel and efficient tandem CD19-and CD22-directed CAR for B cell ALL.
In: Molecular Therapy, Bd. 30, Nr. 2: S. 550-563
Kellner, Markus; Neubeck, Bettina von; Czogalla, Bastian; Feederle, Regina; Vick, Binje; Jeremias, Irmela und Zeidler, Reinhard
(2022):
A Novel Anti-CD73 Antibody That Selectively Inhibits Membrane CD73 Shows Antitumor Activity and Induces Tumor Immune Escape.
In: Biomedicines, Bd. 10, Nr. 4
[PDF, 5MB]
Heinrich, Kathrin; Miller-Phillips, Lisa; Ziemann, Frank; Hasselmann, Korbinian; Rühlmann, Katharina; Flach, Madeleine; Biro, Dorottya; Bergwelt-Baildon, Michael von; Holch, Julian; Herold, Tobias; Baumgarten, Louisa von; Greif, Philip A. 
ORCID: https://orcid.org/0000-0002-3744-7936; Jeremias, Irmela; Wuerstlein, Rachel; Casuscelli, Jozefina; Spitzweg, Christine; Seidensticker, Max; Renz, Bernhard; Corradini, Stefanie; Baumeister, Philipp; Goni, Elisabetta; Tufman, Amanda; Jung, Andreas; Kumbrink, Jörg; Kirchner, Thomas; Klauschen, Frederick; Metzeler, Klaus H.; Heinemann, Volker und Westphalen, C. Benedikt ORCID: https://orcid.org/0000-0002-5310-3754
(2022):
Lessons learned: the first consecutive 1000 patients of the CCCMunich(LMU) Molecular Tumor Board.
In: Journal of Cancer Research and Clinical Oncology, Bd. 149, Nr. 5: S. 1905-1915
[PDF, 728kB]
ORCID: https://orcid.org/0000-0002-3744-7936; Jeremias, Irmela; Wuerstlein, Rachel; Casuscelli, Jozefina; Spitzweg, Christine; Seidensticker, Max; Renz, Bernhard; Corradini, Stefanie; Baumeister, Philipp; Goni, Elisabetta; Tufman, Amanda; Jung, Andreas; Kumbrink, Jörg; Kirchner, Thomas; Klauschen, Frederick; Metzeler, Klaus H.; Heinemann, Volker und Westphalen, C. Benedikt ORCID: https://orcid.org/0000-0002-5310-3754
(2022):
Lessons learned: the first consecutive 1000 patients of the CCCMunich(LMU) Molecular Tumor Board.
In: Journal of Cancer Research and Clinical Oncology, Bd. 149, Nr. 5: S. 1905-1915
[PDF, 728kB]
Zeller, Christina ORCID: https://orcid.org/0000-0003-1834-965X; Richter, Daniel ORCID: https://orcid.org/0000-0003-1302-9083; Jurinovic, Vindi; Valtierra-Gutiérrez, Ilse A. ORCID: https://orcid.org/0000-0003-4128-5914; Jayavelu, Ashok Kumar; Mann, Matthias; Bagnoli, Johannes W. ORCID: https://orcid.org/0000-0003-0393-6157; Hellmann, Ines ORCID: https://orcid.org/0000-0003-0588-1313; Herold, Tobias ORCID: https://orcid.org/0000-0002-9615-9432; Enard, Wolfgang ORCID: https://orcid.org/0000-0002-4056-0550; Vick, Binje ORCID: https://orcid.org/0000-0003-1956-2778 und Jeremias, Irmela ORCID: https://orcid.org/0000-0003-1773-7677
(2022):
Adverse stem cell clones within a single patient’s tumor predict clinical outcome in AML patients.
In: Journal of Hematology & Oncology, Bd. 15, 25
[PDF, 1MB]
ORCID: https://orcid.org/0000-0003-1834-965X; Richter, Daniel ORCID: https://orcid.org/0000-0003-1302-9083; Jurinovic, Vindi; Valtierra-Gutiérrez, Ilse A. ORCID: https://orcid.org/0000-0003-4128-5914; Jayavelu, Ashok Kumar; Mann, Matthias; Bagnoli, Johannes W. ORCID: https://orcid.org/0000-0003-0393-6157; Hellmann, Ines ORCID: https://orcid.org/0000-0003-0588-1313; Herold, Tobias ORCID: https://orcid.org/0000-0002-9615-9432; Enard, Wolfgang ORCID: https://orcid.org/0000-0002-4056-0550; Vick, Binje ORCID: https://orcid.org/0000-0003-1956-2778 und Jeremias, Irmela ORCID: https://orcid.org/0000-0003-1773-7677
(2022):
Adverse stem cell clones within a single patient’s tumor predict clinical outcome in AML patients.
In: Journal of Hematology & Oncology, Bd. 15, 25
[PDF, 1MB]
Tahk, Siret; Vick, Binje; Hiller, Björn; Schmitt, Saskia; Marcinek, Anetta; Perini, Enrico D.; Leutbecher, Alexandra; Augsberger, Christian; Reischer, Anna; Tast, Benjamin; Humpe, Andreas; Jeremias, Irmela; Subklewe, Marion; Fenn, Nadja C. und Hopfner, Karl-Peter
(2021):
SIRP alpha-alpha CD123 fusion antibodies targeting CD123 in conjunction with CD47 blockade enhance the clearance of AML-initiating cells.
In: Journal of Hematology & Oncology, Bd. 14, Nr. 1, 155
Tahk, Siret; Vick, Binje; Hiller, Björn; Schmitt, Saskia; Marcinek, Anetta; Perini, Enrico D.; Leutbecher, Alexandra; Augsberger, Christian; Reischer, Anna; Tast, Benjamin; Humpe, Andreas; Jeremias, Irmela; Subklewe, Marion; Fenn, Nadja C. und Hopfner, Karl-Peter ORCID: https://orcid.org/0000-0002-4528-8357
(2021):
SIRPα-αCD123 fusion antibodies targeting CD123 in conjunction with CD47 blockade enhance the clearance of AML-initiating cells.
In: Journal of hematology & oncology, Bd. 14, 155
[PDF, 3MB]
ORCID: https://orcid.org/0000-0002-4528-8357
(2021):
SIRPα-αCD123 fusion antibodies targeting CD123 in conjunction with CD47 blockade enhance the clearance of AML-initiating cells.
In: Journal of hematology & oncology, Bd. 14, 155
[PDF, 3MB]
Augsberger, Christian; Hanel, Gerulf; Xu, Wei; Pulko, Vesna; Hanisch, Lydia Jasmin; Augustin, Angelique; Challier, John; Hunt, Katharina; Vick, Binje; Rovatti, Pier Eduardo; Krupka, Christina; Rothe, Maurine; Schonle, Anne; Sam, Johannes; Lezan, Emmanuelle; Ducret, Axel; Ortiz-Franyuti, Daniela; Walz, Antje-Christine; Benz, Jorg; Bujotzek, Alexander; Lichtenegger, Felix S.; Gassner, Christian; Carpy, Alejandro; Lyamichev, Victor; Patel, Jigar; Konstandin, Nikola; Tunger, Antje; Schmitz, Marc; Bergwelt-Baildon, Michael von; Spiekermann, Karsten; Vago, Luca; Jeremias, Irmela; Marrer-Berger, Estelle; Umana, Pablo; Klein, Christian und Subklewe, Marion
(2021):
Targeting intracellular WT1 in AML with a novel RMF-peptide-MHC-specific T-cell bispecific antibody.
In: Blood, Bd. 138, Nr. 25: S. 2655-2669
Kempf, Julia M.; Weser, Sabrina; Bartoschek, Michael D.; Metzeler, Klaus H.; Vick, Binje; Herold, Tobias; Voelse, Kerstin; Mattes, Raphael; Scholz, Manuela; Wange, Lucas E.; Festini, Moreno; Ugur, Enes; Roas, Maike; Weigert, Oliver; Bultmann, Sebastian; Leonhardt, Heinrich; Schotta, Gunnar; Hiddemann, Wolfgang; Jeremias, Irmela und Spiekermann, Karsten
(2021):
Loss-of-function mutations in the histone methyltransferase EZH2 promote chemotherapy resistance in AML.
In: Scientific Reports, Bd. 11, Nr. 1, 5838
Lenk, Lennart; Carlet, Michela; Vogiatzi, Fotini; Spory, Lea; Winterberg, Dorothee; Cousins, Antony; Vossen-Gajcy, Michaela; Ibruli, Olta; Vokuhl, Christian; Cario, Gunnar; El Ayoubi, Omar; Kramer, Lisa; Ritgen, Matthias; Bruggemann, Monika; Hasler, Robert; Schrappe, Martin; Fuhrmann, Stephan; Halsey, Christina; Jeremias, Irmela; Hobeika, Elias; Jumaa, Hassan; Alsadeq, Ameera und Schewe, Denis M.
(2021):
CD79a promotes CNS-infiltration and leukemia engraftment in pediatric B-cell precursor acute lymphoblastic leukemia.
In: Communications Biology, Bd. 4, Nr. 1, 73
Liu, Wen-Hsin; Völse, Kerstin; Senft, Daniela und Jeremias, Irmela
(2021):
A reporter system for enriching CRISPR/Cas9 knockout cells in technically challenging settings like patient models.
In: Scientific Reports, Bd. 11, Nr. 1, 12649
Messner, Martina; Mandl, Melanie M.; Hackl, Mathias W.; Reinhardt, Till; Ardelt, Maximilian A.; Szczepanowska, Karolina; Fraedrich, Julian E.; Waschke, Jens; Jeremias, Irmela; Fux, Anja; Stahl, Matthias; Vollmar, Angelika M.; Sieber, Stephan A. und Pachmayr, Johanna
(2021):
Small molecule inhibitors of the mitochondrial ClpXP protease possess cytostatic potential and re-sensitize chemo-resistant cancers.
In: Scientific Reports, Bd. 11, Nr. 1, 11185
Sanchez-Martinez, Diego; Gutierrez-Aguera, Francisco; Romecin, Paola; Vinyoles, Meritxell; Palomo, Marta; Tirado, Nestor; Romina Zanetti, Samanta; Juan, Manel; Carlet, Michela; Jeremias, Irmela und Menendez, Pablo
(2021):
Enforced sialyl-Lewis-X (sLeX) display in E-selectin ligands by exofucosylation is dispensable for CD19-CAR T-cell activity and bone marrow homing.
In: Clinical and Translational Medicine, Bd. 11, Nr. 2, e280
Yankova, Eliza; Blackaby, Wesley; Albertella, Mark; Rak, Justyna; De Braekeleer, Etienne; Tsagkogeorga, Georgia; Pilka, Ewa S.; Aspris, Demetrios; Leggate, Dan; Hendrick, Alan G.; Webster, Natalie A.; Andrews, Byron; Fosbeary, Richard; Guest, Patrick; Irigoyen, Nerea; Eleftheriou, Maria; Gozdecka, Malgorzata; Dias, Joao M. L.; Bannister, Andrew J.; Vick, Binje; Jeremias, Irmela; Vassiliou, George S.; Rausch, Oliver; Tzelepis, Konstantinos und Kouzarides, Tony
(2021):
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia.
In: Nature, Bd. 593, Nr. 7860: S. 597-601
Jensen, Patrizia; Carlet, Michela; Schlenk, Richard F.; Weber, Andrea; Kress, Jana; Brunner, Ines; Slabicki, Mikolaj; Grill, Gregor; Weisemann, Simon; Cheng, Ya-Yun; Jeremias, Irmela; Scholl, Claudia und Froehling, Stefan
(2020):
Requirement for LIM kinases in acute myeloid leukemia.
In: Leukemia, Bd. 34, Nr. 12: S. 3173-3185
Stief, Sophie M.; Hanneforth, Anna-Li; Weser, Sabrina; Mattes, Raphael; Carlet, Michela; Liu, Wen-Hsin; Bartoschek, Michael D.; Moreno, Helena Dominguez; Oettle, Matthias; Kempf, Julia; Vick, Binje; Ksienzyk, Bianka; Tizazu, Belay; Rothenberg-Thurley, Maja; Quentmeier, Hilmar; Hiddemann, Wolfgang; Vosberg, Sebastian; Greif, Philipp A.; Metzeler, Klaus H.; Schotta, Gunnar; Bultmann, Sebastian; Jeremias, Irmela; Leonhardt, Heinrich und Spiekermann, Karsten
(2020):
Loss of KDM6A confers drug resistance in acute myeloid leukemia.
In: Leukemia, Bd. 34, Nr. 1: S. 50-62
Liu, Wen-Hsin; Mrozek-Gorska, Paulina; Wirth, Anna-Katharina; Herold, Tobias; Schwarzkopf, Larissa; Pich, Dagmar; Voelse, Kerstin; Melo-Narvaez, M. Camila; Carlet, Michela; Hammerschmidt, Wolfgang und Jeremias, Irmela
(2020):
Inducible transgene expression in PDX models in vivo identifies KLF4 as a therapeutic target for B-ALL.
In: Biomarker Research, Bd. 8, Nr. 1, 46
Stenger, Dana; Stief, Tanja A.; Kaeuferle, Theresa; Willier, Semjon; Rataj, Felicitas; Schober, Kilian; Vick, Binje; Lotfi, Ramin; Wagner, Beate; Grünewald, Thomas G. P.; Kobold, Sebastian; Busch, Dirk H.; Jeremias, Irmela; Blaeschke, Franziska und Feuchtinger, Tobias
(2020):
Endogenous TCR promotes in vivo persistence of CD19-CAR-T cells compared to a CRISPR/Cas9-mediated TCR knockout CAR.
In: Blood, Bd. 136, Nr. 12: S. 1407-1418
Becker, Martin; Noll-Puchta, Heidi; Amend, Diana; Nolte, Florian; Fuchs, Christiane; Jeremias, Irmela und Braun, Christian J.
(2020):
CLUE: a bioinformatic and wet-lab pipeline for multiplexed cloning of custom sgRNA libraries.
In: Nucleic Acids Research, Bd. 48, Nr. 13, e78
Bamezai, Shiva; Demir, Deniz; Pulikkottil, Alex Jose; Ciccarone, Fabio; Fischbein, Elena; Sinha, Amit; Borga, Chiara; te Kronnie, Geertruy; Meyer, Lueder-Hinrich; Mohr, Fabian; Goetze, Maria; Caiafa, Paola; Debatin, Klaus-Michael; Doehner, Konstanze; Doehner, Hartmut; Gonzalez-Menendez, Irene; Quintanilla-Fend, Leticia; Herold, Tobias; Jeremias, Irmela; Feuring-Buske, Michaela; Buske, Christian und Rawat, Vijay P. S.
(2020):
TET1 promotes growth of T-cell acute lymphoblastic leukemia and can be antagonized via PARP inhibition.
In: Leukemia, Bd. 35, Nr. 2: S. 389-403
Ruzicka, Michael; König, Lars M.; Formisano, Simone; Boehmer, Daniel F. R.; Vick, Binje; Heuer, Eva-M.; Meinl, Hanna; Kocheise, Lorenz; Zeitlhoefler, Marcus; Ahlfeld, Julia; Kobold, Sebastian; Endres, Stefan; Subklewe, Marion; Duewell, Peter; Schnurr, Max; Jeremias, Irmela; Lichtenegger, Felix S. und Rothenfusser, Simon
(2020):
RIG-I-based immunotherapy enhances survival in preclinical AML models and sensitizes AML cells to checkpoint blockade.
In: Leukemia, Bd. 34, Nr. 4: S. 1017-1026
Salik, Basit; Yi, Hangyu; Hassan, Nunki; Santiappillai, Nancy; Vick, Binje; Connerty, Patrick; Duly, Alastair; Trahair, Toby; Woo, Andrew J.; Beck, Dominik; Liu, Tao; Spiekermann, Karsten; Jeremias, Irmela; Wang, Jianlong; Kavallaris, Maria; Haber, Michelle; Norris, Murray D.; Liebermann, Dan A.; D'Andrea, Richard J.; Murriel, Christopher und Wang, Jenny Y.
(2020):
Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia.
In: Cancer Cell, Bd. 38, Nr. 2: S. 263-278
Redondo Monte, Enric; Wilding, Anja; Leubolt, Georg; Kerbs, Paul; Bagnoli, Johannes W.; Hartmann, Luise; Hiddemann, Wolfgang; Chen-Wichmann, Linping; Krebs, Stefan; Blum, Helmut; Cusan, Monica; Vick, Binje; Jeremias, Irmela; Enard, Wolfgang; Theurich, Sebastian; Wichmann, Christian und Greif, Philipp A.
(2020):
ZBTB7A prevents RUNX1-RUNX1T1-dependent clonal expansion of human hematopoietic stem and progenitor cells.
In: Oncogene, Bd. 39: S. 3195-3205
[PDF, 1MB]
Koczian, Fabian; Naglo, Olga; Vomacka, Jan; Vick, Binje; Servatius, Phil; Zisis, Themistoklis; Hettich, Britta; Kazmaier, Uli; Sieber, Stephan A.; Jeremias, Irmela; Zahler, Stefan und Braig, Simone
(2019):
Targeting the endoplasmic reticulum-mitochondria interface sensitizes leukemia cells to cytostatics.
In: Haematologica, Bd. 104, Nr. 3: S. 546-555
Senft, Daniela und Jeremias, Irmela
(2019):
A rare subgroup of leukemia stem cells harbors relapse-inducing potential in acute lymphoblastic leukemia.
In: Experimental Hematology, Bd. 69: S. 1-10
Lynch, Jennifer R.; Salik, Basit; Connerty, Patrick; Vick, Binje; Leung, Halina; Pijning, Aster; Jeremias, Irmela; Spiekermann, Karsten; Trahair, Toby; Liu, Tao; Haber, Michelle; Norris, Murray D.; Woo, Andrew J.; Hogg, Philip; Wang, Jianlong und Wang, Jenny Y.
(2019):
JMJD1C-mediated metabolic dysregulation contributes to HOXA9-dependent leukemogenesis.
In: Leukemia, Bd. 33, Nr. 6: S. 1400-1410
Gaiser, Ann-Kathrin; Hafner, Susanne; Schmiech, Michael; Buchele, Berthold; Schafer, Patrick; Arnim, Christine A. von; Calzia, Enrico; Feuring-Buske, Michaela; Buske, Christian; Vick, Binje; Jeremias, Irmela; Syrovets, Tatiana und Simmet, Thomas
(2019):
Gold Nanoparticles with Selective Antileukemic Activity In Vitro and In Vivo Target Mitochondrial Respiration.
In: Advanced Therapeutics, Bd. 2, Nr. 6, UNSP 1800149
Pan, Chenchen; Schoppe, Oliver; Parra-Damas, Arnaldo; Cai, Ruiyao; Todorov, Mihail Ivilinov; Gondi, Gabor; Neubeck, Bettina von; Boeguercue-Seidel, Nuray; Seidel, Sascha; Sleiman, Katia; Veltkamp, Christian; Foerstera, Benjamin; Mai, Hongcheng; Rong, Zhouyi; Trompak, Omelyan; Ghasemigharagoz, Alireza; Reimer, Madita Alice; Cuesta, Angel M.; Coronel, Javier; Jeremias, Irmela; Saur, Dieter; Acker-Palmer, Amparo; Acker, Till; Garvalov, Boyan K.; Menze, Björn; Zeidler, Reinhard und Ertuerk, Ali
(2019):
Deep Learning Reveals Cancer Metastasis and Therapeutic Antibody Targeting in the Entire Body.
In: Cell, Bd. 179, Nr. 7
[PDF, 1MB]
Kirsch, Volker C.; Orgler, Christina; Braig, Simone; Jeremias, Irmela; Auerbach, David; Müller, Rolf; Vollmar, Angelika M. und Sieber, Stephan A.
(2019):
The Cytotoxic Natural Product Vioprolide A Targets Nucleolar Protein 14, which is Essential for Ribosome Biogenesis.
In: Angewandte Chemie-International Edition, Bd. 59, Nr. 4: S. 1595-1600
Sarrach, Sannia; Huang, Yuanchi; Niedermeyer, Sebastian; Hachmeister, Matthias; Fischer, Laura; Gille, Sebastian; Pan, Min; Mack, Brigitte; Kranz, Gisela; Libl, Darko; Merl-Pham, Juliane; Hauck, Stefanie M.; Tomada, Elisa Paoluzzi; Kieslinger, Matthias; Jeremias, Irmela; Scialdone, Antonio und Gires, Olivier
(2018):
Spatiotemporal patterning of EpCAM is important for murine embryonic endo- and mesodermal differentiation.
In: Scientific Reports, Bd. 8, 1801
[PDF, 9MB]
Tzelepis, Konstantinos; De Braekeleer, Etienne; Aspris, Demetrios; Barbieri, Isaia; Vijayabaskar, M. S.; Liu, Wen-Hsin; Gozdecka, Malgorzata; Metzakopian, Emmanouil; Toop, Hamish D.; Dudek, Monika; Robson, Samuel C.; Hermida-Prado, Francisco; Yang, Yu Hsuen; Babaei-Jadidi, Roya; Garyfallos, Dimitrios A.; Ponstingl, Hannes; Dias, Joao M. L.; Gallipoli, Paolo; Seiler, Michael; Buonamici, Silvia; Vick, Binje; Bannister, Andrew J.; Rad, Roland; Prinjha, Rab K.; Marioni, John C.; Huntly, Brian; Batson, Jennifer; Morris, Jonathan C.; Pina, Cristina; Bradley, Allan; Jeremias, Irmela; Bates, David O.; Yusa, Kosuke; Kouzarides, Tony und Vassiliou, George S.
(2018):
SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4.
In: Nature Communications, Bd. 9, 5378
[PDF, 2MB]
Göllner, Stefanie; öllerich, Thomas; Agrawal-Singh, Shuchi; Schenk, Tino; Klein, Hans-Ulrich; Rohde, Christian; Pabst, Caroline; Sauer, Tim; Lerdrup, Mads; Tavor, Sigal; Stölzel, Friedrich; Herold, Sylvia; Ehninger, Gerhard; Köhler, Gabriele; Pan, Kuan-Ting; Urlaub, Henning; Serve, Hubert; Dugas, Martin; Spiekermann, Karsten; Vick, Binje; Jeremias, Irmela; Berdel, Wolfgang E.; Hansen, Klaus; Zelent, Arthur; Wickenhauser, Claudia; Müller, Lutz P.; Thiede, Christian und Müller-Tidow, Carsten
(2017):
Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia.
In: Nature Medicine, Bd. 23, Nr. 1: S. 69-78
Finkenzeller, Cornelia; Carlet, Michela; Vosberg, Sebastian; Neumann, Martin; Riecken, Kristoffer; Cornils, Kerstin; Fehse, Boris; Baldus, Claudia D.; Greif, Philipp A. und Jeremias, Irmela
(2017):
Clones with and without Sensitivity towards Treatment in Vivo Co-Exist within a Single Sample of a Patient with ALL.
In: Annals of Hematology, Bd. 96:
S75-S75
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The target landscape of clinical kinase drugs.
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Characterization of Rare, Dormant, and Therapy-Resistant Cells in Acute Lymphoblastic Leukemia.
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(2016):
Novel genetically engineered patient-derived xenograft (GEPDX) models reveal that XIAP plays an essential role for patients’ all growing in mice.
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Characterization of covariables modulating CD33/CD3 BITE antibody construct mediated cytotoxicity against primary AML cells.
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An Advanced Preclinical Mouse Model for Acute Myeloid Leukemia Using Patients' Cells of Various Genetic Subgroups and In Vivo Bioluminescence Imaging.
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In: PLOS ONE 10(3), e0120925 [PDF, 3MB]
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[PDF, 443kB]
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In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice.
In: PLOS ONE 7(12), e52798 [PDF, 1MB]
In: PLOS ONE 7(12), e52798 [PDF, 1MB]
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Efficient RNA interference in patients' acute lymphoblastic leukemia cells amplified as xenografts in mice.
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[PDF, 1MB]
Buchbeitrag
Jeremias, Irmela und Schewe, Denis M.
(2018):
Characteristics and Therapeutic Targeting of Minimal Residual Disease in Childhood Acute Lymphoblastic Leukemia.
In:
Springer. S. 127-139