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Veröffentlichungsdatum
Anzahl der Publikationen: 8
2022
Glas, Carina; Naydenova, Eli; Lechner, Severin; Woessner, Nathalie; Yang, Liu; Dietschreit, Johannes C. B.; Sun, Hongyan; Jung, Manfred; Kuster, Bernhard; Ochsenfeld, Christian und Bracher, Franz
(2022):
Development of hetero-triaryls as a new chemotype for subtype-selective and potent Sirt5 inhibition.
In: European Journal of Medicinal Chemistry, Bd. 240, 114594
2021
Fuhrmann, Lars; Lindner, Saskia; Hauser, Alexander-Thomas; Hoese, Clemens; Kretz, Oliver; Cohen, Clemens D.; Lindenmeyer, Maja T.; Sippl, Wolfgang; Jung, Manfred; Huber, Tobias B. und Wanner, Nicola
(2021):
Effects of Environmental Conditions on Nephron Number: Modeling Maternal Disease and Epigenetic Regulation in Renal Development.
In: International Journal of Molecular Sciences, Bd. 22, Nr. 8, 4157
2020
Glas, Carina; Dietschreit, Johannes C. B.; Woessner, Nathalie; Urban, Lars; Ghazy, Ehab; Sippl, Wolfgang; Jung, Manfred; Ochsenfeld, Christian und Bracher, Franz
(2020):
Identification of the subtype-selective Sirt5 inhibitor balsalazide through systematic SAR analysis and rationalization via theoretical investigations.
In: European Journal of Medicinal Chemistry, Bd. 206, 112676
2019
Metzger, Eric; Wang, Sheng; Urban, Sylvia; Willmann, Dominica; Schmidt, Andreas; Offermann, Anne; Allen, Anita; Sum, Manuela; Obier, Nadine; Cottard, Felicie; Ulferts, Svenja; Preca, Bogdan-Tiberius; Hermann, Bianca; Maurer, Jochen; Greschik, Holger; Hornung, Veit; Einsle, Oliver; Perner, Sven; Imhof, Axel; Jung, Manfred und Schuele, Roland
(2019):
KMT9 monomethylates histone H4 lysine 12 and controls proliferation of prostate cancer cells.
In: Nature Structural & Molecular Biology, Bd. 26, Nr. 5
Voegerl, Katharina; Ong, Nghia; Senger, Johanna; Herp, Daniel; Schmidtkunz, Karin; Marek, Martin; Müller, Martin; Bartel, Karin; Shaik, Tajith B.; Porter, Nicholas J.; Robaa, Dina; Christianson, David W.; Romier, Christophe; Sippl, Wolfgang; Jung, Manfred und Bracher, Franz
(2019):
Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors.
In: Journal of Medicinal Chemistry, Bd. 62, Nr. 3: S. 1138-1166
2017
Ong, Duc Nghia; Dittrich, Sebastian; Swyter, Sören; Jung, Manfred und Bracher, Franz
(2017):
Synthesis of highly substituted 3-arylideneindolin-2-ones.
In: Tetrahedron, Bd. 73, Nr. 38: S. 5668-5679
2016
Metzger, Eric; Willmann, Dominica; McMillan, Joel; Forne, Ignasi; Metzger, Philipp; Gerhardt, Stefan; Petroll, Kerstin; Maessenhausen, Anne von; Urban, Sylvia; Schott, Anne-Kathrin; Espejo, Alexsandra; Eberlin, Adrien; Wohlwend, Daniel; Schüle, Katrin M.; Schleicher, Michael; Perner, Sven; Bedford, Mark T.; Jung, Manfred; Dengjel, Jörn; Flaig, Ralf; Imhof, Axel; Einsle, Oliver und Schüle, Roland
(2016):
Assembly of methylated KDM1A and CHD1 drives androgen receptor-dependent transcription and translocation.
In: Nature Structural & Molecular Biology, Bd. 23, Nr. 2: S. 132-139
2014
Schmitt, Martin L.; Ladwein, Kathrin I.; Carlino, Luca; Schulz-Fincke, Johannes; Willmann, Dominica; Metzger, Eric; Schilcher, Pierre; Imhof, Axel; Schüle, Roland; Sippl, Wolfgang und Jung, Manfred
(2014):
Heterogeneous Antibody-Based Activity Assay for Lysine Specific Demethylase 1 (LSD1) on a Histone Peptide Substrate.
In: SLAS Discovery, Bd. 19, Nr. 6: S. 973-978
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