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Anzahl der Publikationen: 9
Zeitschriftenartikel
Feng, Ruoqing; Spieth, Lena; Liu, Lu; Berghoff, Stefan 
ORCID: https://orcid.org/0000-0002-3794-7295; Franz, Jonas; Liu, Qian; Wang, Zhen; Tiwari, Vini; Vitale, Simona; Frerich, Simon ORCID: https://orcid.org/0000-0002-8275-6113; Florensa, Sergi; Junker, Niklas; Huber, Ludwig; Keller, Marco; Müller, Christoph ORCID: https://orcid.org/0000-0002-1163-2527; Bracher, Franz ORCID: https://orcid.org/0000-0003-0009-8629; Ge, Xiaoke; Rensen, Patrick C.N.; Kooij, Gijs; Hosang, Leon; Chornyi, Serhii; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Gokce, Ozgun; Saher, Gesine; Stadelmann, Christine; Giera, Martin; Groh, Janos ORCID: https://orcid.org/0000-0002-7628-0163 und Simons, Mikael ORCID: https://orcid.org/0000-0001-5329-192X
(2025):
Single-cell spatial transcriptomic profiling defines a pathogenic inflammatory niche in chronic active multiple sclerosis lesions.
In: Immunity [Forthcoming]
ORCID: https://orcid.org/0000-0002-3794-7295; Franz, Jonas; Liu, Qian; Wang, Zhen; Tiwari, Vini; Vitale, Simona; Frerich, Simon ORCID: https://orcid.org/0000-0002-8275-6113; Florensa, Sergi; Junker, Niklas; Huber, Ludwig; Keller, Marco; Müller, Christoph ORCID: https://orcid.org/0000-0002-1163-2527; Bracher, Franz ORCID: https://orcid.org/0000-0003-0009-8629; Ge, Xiaoke; Rensen, Patrick C.N.; Kooij, Gijs; Hosang, Leon; Chornyi, Serhii; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Gokce, Ozgun; Saher, Gesine; Stadelmann, Christine; Giera, Martin; Groh, Janos ORCID: https://orcid.org/0000-0002-7628-0163 und Simons, Mikael ORCID: https://orcid.org/0000-0001-5329-192X
(2025):
Single-cell spatial transcriptomic profiling defines a pathogenic inflammatory niche in chronic active multiple sclerosis lesions.
In: Immunity [Forthcoming]
Scotto Rosato, Anna; Krogsaeter, Einar K; Jaślan, Dawid; Abrahamian, Carla; Montefusco, Sandro; Soldati, Chiara; Spix, Barbara; Pizzo, Maria Teresa; Grieco, Giuseppina; Böck, Julia; Wyatt, Amanda; Wünkhaus, Daniela; Passon, Marcel; Stieglitz, Marc; Keller, Marco; Hermey, Guido; Markmann, Sandra; Gruber‐Schoffnegger, Doris; Cotman, Susan; Johannes, Ludger; Crusius, Dennis; Boehm, Ulrich; Wahl-Schott, Christian; Biel, Martin; Bracher, Franz; De Leonibus, Elvira; Polishchuk, Elena; Medina, Diego L; Paquet, Dominik und Grimm, Christian
(5. August 2022):
TPC2 rescues lysosomal storage in mucolipidosis type IV , Niemann–Pick type C1, and Batten disease.
In: EMBO Molecular Medicine, Bd. 14, Nr. 9
[PDF, 27MB]
Yuan, Yu; Jaslan, Dawid; Rahman, Taufiq; Bolsover, Stephen R.; Arige, Vikas; Wagner, Larry E.; Abrahamian, Carla; Tang, Rachel; Keller, Marco; Hartmann, Jonas; Rosato, Anna S.; Weiden, Eva-Maria; Bracher, Franz; Yule, David I.; Grimm, Christian und Patel, Sandip
(2022):
Segregated cation flux by TPC2 biases Ca2+ signaling through lysosomes.
In: Nature Communications, Bd. 13, Nr. 1, 4481
Keller, Marco; Sauvageot-Witzku, Karl; Geisslinger, Franz; Urban, Nicole; Schaefer, Michael; Bartel, Karin und Bracher, Franz
(2021):
The ethoxycarbonyl group as both activating and protective group in N-acyl-Pictet-Spengler reactions using methoxystyrenes. A short approach to racemic 1-benzyltetrahydroisoquinoline alkaloids.
In: Beilstein Journal of Organic Chemistry, Bd. 17: S. 2716-2725
Leser, Charlotte; Keller, Marco; Gerndt, Susanne; Urban, Nicole; Chen, Cheng-Chang; Schaefer, Michael; Grimm, Christian und Bracher, Franz
(2021):
Chemical and pharmacological characterization of the TRPML calcium channel blockers ML-SI1 and ML-SI3.
In: European Journal of Medicinal Chemistry, Bd. 210, 112966
Gerndt, Susanne; Chen, Cheng-Chang; Chao, Yu-Kai; Yuan, Yu; Burgstaller, Sandra; Rosato, Anna Scotto; Krogsaeter, Einar; Urban, Nicole; Jacob, Katharina; Ong, Nam Phuong Nguyen; Miller, Meghan T.; Keller, Marco; Vollmar, Angelika M.; Gudermann, Thomas; Zierler, Susanna; Schredelseker, Johann; Schaefer, Michael; Biel, Martin; Malli, Roland; Wahl-Schott, Christian; Bracher, Franz; Patel, Sandip und Grimm, Christian
(2020):
Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function.
In: eLife, Bd. 9, e54712
[PDF, 4MB]
Plesch, Eva; Chen, Cheng-Chang; Butz, Elisabeth; Rosato, Anna Scotto; Krogsaeter, Einar K.; Yinan, Hua; Bartel, Karin; Keller, Marco; Robaa, Dina; Teupser, Daniel; Holdt, Lesca M.; Vollmar, Angelika M.; Sippl, Wolfgang; Puertollano, Rosa; Medina, Diego; Biel, Martin; Wahl-Schott, Christian; Bracher, Franz und Grimm, Christian
(2018):
Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells.
In: eLife, Bd. 7, e39720
[PDF, 4MB]
Keller, Marco; Wolfgardt, Annette; Müller, Christoph; Wilcken, Rainer; Böckler, Frank M.; Oliaro-Bosso, Simonetta; Ferrante, Terenzio; Balliano, Gianni und Bracher, Franz
(2016):
Arylpiperidines as a new class of oxidosqualene cyclase inhibitors.
In: European Journal of Medicinal Chemistry, Bd. 109: S. 13-22
Chen, Cheng-Chang; Keller, Marco; Hess, Martin; Schiffmann, Raphael; Urban, Nicole; Wolfgardt, Annette; Schaefer, Michael; Bracher, Franz; Biel, Martin; Wahl-Schott, Christian und Grimm, Christian
(2014):
A small molecule restores function to TRPML1 mutant isoforms responsible for mucolipidosis type IV.
In: Nature Communications, Bd. 5, 4681
[PDF, 1MB]