Publikationen von Lichtenthaler, Stefan F.

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Anzahl der Publikationen: 52

Zeitschriftenartikel

Biechele, Gloria; Monasor, Laura Sebastian; Wind, Karin; Blume, Tanja; Parhizkar, Samira; Arzberger, Thomas; Sacher, Christian; Beyer, Leonie; Eckenweber, Florian; Gildehaus, Franz-Josef; Ungern-Sternberg, Barbara von; Willem, Michael; Bartenstein, Peter; Cumming, Paul; Rominger, Axel; Herms, Jochen; Lichtenthaler, Stefan F.; Haass, Christian; Tahirovic, Sabina und Brendel, Matthias (2022): Glitter in the Darkness? Nonfibrillar beta-Amyloid Plaque Components Significantly Impact the beta-Amyloid PET Signal in Mouse Models of Alzheimer Disease. In: Journal of Nuclear Medicine, Bd. 63, Nr. 1: S. 117-124

Guener, Goekhan; Assfalg, Marlene; Zhao, Kai; Dreyer, Tobias; Lahiri, Shibojyoti; Lo, Yun; Slivinschi, Bianca Ionela; Imhof, Axel; Jocher, Georg; Strohm, Laura; Behrends, Christian; Langosch, Dieter; Bronger, Holger; Nimsky, Christopher; Bartsch, Joerg W.; Riddell, Stanley R.; Steiner, Harald und Lichtenthaler, Stefan F. (2022): Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for gamma-secretase activity. In: EMBO Molecular Medicine, Bd. 14, Nr. 10, e16084

Jocher, Georg; Grass, Vincent; Tschirner, Sarah K.; Riepler, Lydia; Breimann, Stephan; Kaya, Tugberk; Oelsner, Madlen; Hamad, M. Sabri; Hofmann, Laura I.; Blobel, Carl P.; Schmidt-Weber, Carsten B.; Gökce, Özgün; Jakwerth, Constanze A.; Trimpert, Jakob; Kimpel, Janine; Pichlmair, Andreas und Lichtenthaler, Stefan F. (2022): ADAM10 and ADAM17 promote SARS-CoV-2 cell entry and spike protein-mediated lung cell fusion. In: EMBO Reports, Bd. 23, Nr. 6, e54305

Lichtenthaler, Stefan F.; Tschirner, Sarah K. und Steiner, Harald (2022): Secretases in Alzheimer's disease: Novel insights into proteolysis of APP and TREM2. In: Current Opinion in Neurobiology, Bd. 72: S. 101-110

Papadopoulou, Alkmini A.; Stelzer, Walter; Silber, Mara; Schlosser, Christine; Spitz, Charlotte; Haug-Kröper, Martina; Straub, Tobias; Mueller, Stephan A.; Lichtenthaler, Stefan F.; Muhle-Goll, Claudia; Langosch, Dieter und Fluhrer, Regina (2022): Helical stability of the GnTV transmembrane domain impacts on SPPL3 dependent cleavage. In: Scientific Reports, Bd. 12, Nr. 1, 20987

Eninger, Timo; Mueller, Stephan A.; Bacioglu, Mehtap; Schweighauser, Manuel; Lambert, Marius; Maia, Luis F.; Neher, Jonas J.; Hornfeck, Sarah M.; Obermueller, Ulrike; Kleinberger, Gernot; Haass, Christian; Kahle, Philipp J.; Staufenbiel, Matthias; Ping, Lingyan; Duong, Duc M.; Levey, Allan I.; Seyfried, Nicholas T.; Lichtenthaler, Stefan F.; Jucker, Mathias und Kaeser, Stephan A. (2022): Signatures of glial activity can be detected in the CSF proteome. In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 119, Nr. 24, e2119804119

Martin-de-Saavedra, M. Dolores; Dos Santos, Marc; Culotta, Lorenza; Varea, Olga; Spielman, Benjamin P.; Parnell, Euan; Forrest, Marc P.; Gao, Ruoqi; Yoon, Sehyoun; McCoig, Emmarose; Jalloul, Hiba A.; Myczek, Kristoffer; Khalatyan, Natalia; Hall, Elizabeth A.; Turk, Liam S.; Sanz-Clemente, Antonio; Comoletti, Davide; Lichtenthaler, Stefan F.; Burgdorf, Jeffrey S.; Barbolina, Maria V.; Savas, Jeffrey N. und Penzes, Peter (2022): Shed CNTNAP2 ectodomain is detectable in CSF and regulates Ca2+ homeostasis and network synchrony via PMCA2/ATP2B2. In: Neuron, Bd. 110, Nr. 4, E9: S. 627-643

Schneider, Marius F.; Müller, Veronika; Müller, Stephan A.; Lichtenthaler, Stefan F.; Becker, Peter B. und Scheuermann, Johanna C. (2022): LncRNA RUS shapes the gene expression program towards neurogenesis. In: Life Science Alliance, Bd. 5, Nr. 10 [PDF, 3MB]

Zellner, Andreas; Müller, Stephan A.; Lindner, Barbara; Beaufort, Nathalie; Rozemuller, Annemieke J. M.; Arzberger, Thomas; Gassen, Nils C.; Lichtenthaler, Stefan F.; Kuster, Bernhard; Haffner, Christof und Dichgans, Martin (2022): Proteomic profiling in cerebral amyloid angiopathy reveals an overlap with CADASIL highlighting accumulation of HTRA1 and its substrates. In: Acta neuropathologica communications, Bd. 10, 6 [PDF, 37MB]

Boehmer, Daniel F. R.; Formisano, Simone; Mann, Carina C. de Oliveira; Mueller, Stephan A.; Kluge, Michael; Metzger, Philipp; Rohlfs, Meino; Hoerth, Christine; Kocheise, Lorenz; Lichtenthaler, Stefan F.; Hopfner, Karl-Peter; Endres, Stefan; Rothenfusser, Simon; Friedel, Caroline C.; Duewell, Peter; Schnurr, Max und Koenig, Lars M. (2021): OAS1/RNase L executes RIG-I ligand-dependent tumor cell apoptosis. In: Science Immunology, Bd. 6, Nr. 61, eabe2550

Colombo, Alessio; Dinkel, Lina; Mueller, Stephan A.; Monasor, Laura Sebastian; Schifferer, Martina; Cantuti-Castelvetri, Ludovico; Koenig, Jasmin; Vidatic, Lea; Bremova-Ertl, Tatiana; Lieberman, Andrew P.; Hecimovic, Silva; Simons, Mikael; Lichtenthaler, Stefan F.; Strupp, Michael; Schneider, Susanne A. und Tahirovic, Sabina (2021): Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia. In: Nature Communications, Bd. 12, Nr. 1, 1158 [PDF, 7MB]

Macrini, Caterina; Gerhards, Ramona; Winklmeier, Stephan; Bergmann, Lena; Mader, Simone; Spadaro, Melania; Vural, Atay; Smolle, Michaela; Hohlfeld, Reinhard; Kuempfel, Tania; Lichtenthaler, Stefan F.; Franquelim, Henri G.; Jenne, Dieter und Meinl, Edgar (2021): Features of MOG required for recognition by patients with MOG antibody-associated disorders. In: Brain, Bd. 144: S. 2375-2389

Ong-Palsson, Emma; Njavro, Jasenka Rudan; Wilson, Yvette; Pigoni, Martina; Schmidt, Andree; Mueller, Stephan A.; Meyer, Michael; Hartmann, Jana; Busche, Marc Aurel; Gunnersen, Jenny M.; Munro, Kathryn M. und Lichtenthaler, Stefan F. (2021): The beta-Secretase Substrate Seizure 6-Like Protein (SEZ6L) Controls Motor Functions in Mice. In: Molecular Neurobiology, Bd. 59, Nr. 2: S. 1183-1198

Tueshaus, Johanna; Mueller, Stephan A.; Shrouder, Joshua; Arends, Martina; Simons, Mikael; Plesnila, Nikolaus; Blobel, Carl P. und Lichtenthaler, Stefan F. (2021): The pseudoprotease iRhom1 controls ectodomain shedding of membrane proteins in the nervous system. In: Faseb Journal, Bd. 35, Nr. 11, e21962

Kumar, Rohit; Tang, Qilin; Müller, Stephan A.; Gao, Pan; Mahlstedt, Diana; Zampagni, Sofia; Tan, Yi; Klingl, Andreas; Bötzel, Kai; Lichtenthaler, Stefan F.; Höglinger, Günter U. und Köglsperger, Thomas (2020): Fibroblast Growth Factor 2-Mediated Regulation of Neuronal Exosome Release Depends on VAMP3/Cellubrevin in Hippocampal Neurons. In: Advanced Science, Bd. 7, Nr. 6, 1902372

Monasor, Laura Sebastian; Müller, Stephan A.; Colombo, Alessio Vittorio; Tanrioever, Gaye; König, Jasmin; Roth, Stefan; Liesz, Arthur; Berghofer, Anna; Piechotta, Anke; Prestel, Matthias; Saito, Takashi; Saido, Takaomi C.; Herms, Jochen; Willem, Michael; Haass, Christian; Lichtenthaler, Stefan F. und Tahirovic, Sabina (2020): Fibrillar Aβ (beta) triggers microglial proteome alterations and dysfunction in Alzheimer mouse models. In: eLife, Bd. 9, e54083 [PDF, 14MB]

Pigoni, Martina; Hsia, Hung-En; Hartmann, Jana; Rudan Njavro, Jasenka; Shmueli, Merav D.; Müller, Stephan A.; Guener, Goekhan; Tueshaus, Johanna; Kuhn, Peer-Hendrik; Kumar, Rohit; Gao, Pan; Tran, Mai Ly; Ramazanov, Bulat; Blank, Birgit; Hipgrave Ederveen, Agnes L.; Blume, Julia von; Mulle, Christophe; Gunnersen, Jenny M.; Wuhrer, Manfred; Rammes, Gerhard; Busche, Marc Aurel; Köglsperger, Thomas und Lichtenthaler, Stefan F. (2020): Seizure protein 6 controls glycosylation and trafficking of kainate receptor subunits GluK2 and GluK3. In: EMBO Journal, Bd. 39, Nr. 15, e103457

Gerhards, Ramona; Pfeffer, Lena Kristina; Lorenz, Jessica; Starost, Laura; Nowack, Luise; Thaler, Franziska S.; Schlueter, Miriam; Ruebsamen, Heike; Macrini, Caterina; Winklmeier, Stephan; Mader, Simone; Bronge, Mattias; Groenlund, Hans; Feederle, Regina; Hsia, Hung-En; Lichtenthaler, Stefan F.; Merl-Pham, Juliane; Hauck, Stefanie M.; Kuhlmann, Tanja; Bauer, Isabel J.; Beltran, Eduardo; Gerdes, Lisa Ann; Mezydlo, Aleksandra; Bar-Or, Amit; Banwell, Brenda; Khademi, Mohsen; Olsson, Tomas; Hohlfeld, Reinhard; Lassmann, Hans; Kuempfel, Tania; Kawakami, Naoto und Meinl, Edgar (2020): Oligodendrocyte myelin glycoprotein as a novel target for pathogenic autoimmunity in the CNS. In: Acta Neuropathologica Communications, Bd. 8, Nr. 1, 207

Cunha, Maria Ines; Su, Minhui; Cantuti-Castelvetri, Ludovico; Müller, Stephan A.; Schifferer, Martina; Djannatian, Minou; Alexopoulos, Ioannis; Meer, Franziska van der; Winkler, Anne; Ham, Tjakko J. van; Schmid, Bettina; Lichtenthaler, Stefan F.; Stadelmann, Christine und Simons, Mikael (2020): Pro-inflammatory activation following demyelination is required for myelin clearance and oligodendrogenesis. In: Journal of Experimental Medicine, Bd. 217, Nr. 5, e20191390

Kumar, Rohit; Donakonda, Sainitin; Müller, Stephan A.; Lichtenthaler, Stefan F.; Bötzel, Kai; Höglinger, Günter U. und Köglsperger, Thomas (2020): Basic Fibroblast Growth Factor 2-Induced Proteome Changes Endorse Lewy Body Pathology in Hippocampal Neurons. In: Iscience, Bd. 23, Nr. 8, 101349

Bartels, Martin; Weckbecker, Daniel; Kuhn, Peer-Hendrik; Ryazanov, Sergey; Leonov, Andrei; Griesinger, Christian; Lichtenthaler, Stefan F.; Boetzel, Kai und Giese, Armin (2019): Iron-mediated aggregation and toxicity in a novel neuronal cell culture model with inducible alpha-synuclein expression. In: Scientific Reports, Bd. 9, 9100 [PDF, 7MB]

Fecher, Caroline; Trovo, Laura; Müller, Stephan A.; Snaidero, Nicolas; Wettmarshausen, Jennifer; Heink, Sylvia; Ortiz, Oskar; Wagner, Ingrid; Kühn, Ralf; Hartmann, Jana; Karl, Rosa Maria; Konnerth, Arthur; Korn, Thomas; Wurst, Wolfgang; Merkler, Doron; Lichtenthaler, Stefan F.; Perocchi, Fabiana und Misgeld, Thomas (2019): Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity. In: Nature Neuroscience, Bd. 22, Nr. 10

Parhizkar, Samira; Arzberger, Thomas; Brendel, Matthias; Kleinberger, Gernot; Deussing, Maximilian; Focke, Carola; Nuscher, Brigitte; Xiong, Monica; Ghasemigharagoz, Alireza; Katzmarski, Natalie; Krasemann, Susanne; Lichtenthaler, Stefan F.; Müller, Stephan A.; Colombo, Alessio; Monasor, Laura Sebastian; Tahirovic, Sabina; Herms, Jochen; Willem, Michael; Pettkus, Nadine; Butovsky, Oleg; Bartenstein, Peter; Edbauer, Dieter; Rominger, Axel; Ertuerk, Ali; Grathwohl, Stefan A.; Neher, Jonas J.; Holtzman, David M.; Meyer-Luehmann, Melanie und Haass, Christian (2019): Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE. In: Nature Neuroscience, Bd. 22, Nr. 2

Papadopoulou, Alkmini A.; Müller, Stephan A.; Mentrup, Torben; Shmueli, Merav D.; Niemeyer, Johannes; Haug-Kroeper, Martina; Blume, Julia von; Mayerhofer, Artur; Feederle, Regina; Schröder, Bernd; Lichtenthaler, Stefan F. und Fluhrer, Regina (2019): Signal Peptide Peptidase-Like 2c (SPPL2c) impairs vesicular transport and cleavage of SNARE proteins. In: EMBO Reports, Bd. 20, Nr. 3, e46451

Niemeyer, Johannes; Mentrup, Torben; Heidasch, Ronny; Müller, Stephan A.; Biswas, Uddipta; Meyer, Rieke; Papadopoulou, Alkmini A.; Dederer, Verena; Haug-Kroeper, Martina; Adamski, Vivian; Luellmann-Rauch, Renate; Bergmann, Martin; Mayerhofer, Artur; Saftig, Paul; Wennemuth, Gunther; Jessberger, Rolf; Fluhrer, Regina; Lichtenthaler, Stefan F.; Lemberg, Marius K. und Schröder, Bernd (2019): The intramembrane protease SPPL2c promotes male germ cell development by cleaving phospholamban. In: EMBO Reports, Bd. 20, Nr. 3, e46449

Brummer, Tobias; Müller, Stephan A.; Pan-Montojo, Francisco; Yoshida, Fumiaki; Fellgiebel, Andreas; Tomita, Taisuke; Endres, Kristina und Lichtenthaler, Stefan F. (2019): NrCAM is a marker for substrate-selective activation of ADAM10 in Alzheimer's disease. In: EMBO Molecular Medicine, Bd. 11, Nr. 4, e9695

Peters, Finn; Salihoglu, Hazal; Pratsch, Katrin; Herzog, Etienne; Pigoni, Martina; Sgobio, Carmelo; Lichtenthaler, Stefan F.; Neumann, Ulf und Herms, Jochen (2019): Tau deletion reduces plaque-associated BACE1 accumulation and decelerates plaque formation in a mouse model of Alzheimer's disease. In: EMBO Journal, Bd. 38, Nr. 23, e102345

Rudan Njavro, Jasenka; Klotz, Jakob; Dislich, Bastian; Wanngren, Johanna; Shmueli, Merav D.; Herber, Julia; Kuhn, Peer-Hendrik; Kumar, Rohit; Koeglsperger, Thomas; Conrad, Marcus; Wurst, Wolfgang; Feederle, Regina; Vlachos, Andreas; Michalakis, Stylianos; Jedlicka, Peter; Müller, Stephan A. und Lichtenthaler, Stefan F. (2019): Mouse brain proteomics establishes MDGA1 and CACHD1 as in vivo substrates of the Alzheimer protease BACE1. In: Faseb Journal, Bd. 34, Nr. 2: S. 2465-2482

Montagna, Elena; Crux, Sophie; Luckner, Manja; Herber, Julia; Colonnbo, Alessio; Marinkovic, Petar; Tahirovic, Sabina; Lichtenthaler, Stefan F.; Wanner, Gerhard; Müller, Ulrike C.; Sgobio, Carmelo und Herms, Jochen (2019): In vivo Ca2+ imaging of astrocytic microdomains reveals a critical role of the amyloid precursor protein for mitochondria. In: Glia, Bd. 67, Nr. 5: S. 985-998

Blume, Tanja; Filser, Severin; Jaworska, Anna; Blain, Jean-Francois; König, Gerhard; Moschke, Katrin; Lichtenthaler, Stefan F. und Herms, Jochen (2018): BACE1 Inhibitor MK-8931 Alters Formation but Not Stability of Dendritic Spines. In: Frontiers in Aging Neuroscience, Bd. 10, 229 [PDF, 1MB]

Zhu, Kaichuan; Xiang, Xianyuan; Filser, Severin; Marinkovic, Petar; Dorostkar, Mario M.; Crux, Sophie; Neumann, Ulf; Shimshek, Derya R.; Rammes, Gerhard; Haass, Christian

; Lichtenthaler, Stefan F.; Gunnersen, Jenny M. und Herms, Jochen (2018): Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibition Impairs Synaptic Plasticity via Seizure Protein 6. In: Biological Psychiatry, Bd. 83, Nr. 5: S. 428-437

Zellner, Andreas; Scharrer, Eva; Arzberger, Thomas; Oka, Chio; Domenga-Denier, Valerie; Joutel, Anne; Lichtenthaler, Stefan F.; Müller, Stephan A.; Dichgans, Martin und Haffner, Christof (2018): CADASIL brain vessels show a HTRA1 loss-of-function profile. In: Acta Neuropathologica, Bd. 136, Nr. 1: S. 111-125

Abdullahi, Sarah; Jaekel, Melanie; Behrend, Sabine J.; Steiger, Katja; Topping, Geoffrey; Krabbe, Teresa; Colombo, Alessio; Sandig, Volker; Schiergens, Tobias S.; Thasler, Wolfgang E.; Werner, Jens; Lichtenthaler, Stefan F.; Schmid, Roland M.; Ebert, Oliver und Altomonte, Jennifer (2018): A Novel Chimeric Oncolytic Virus Vector for Improved Safety and Efficacy as a Platform for the Treatment of Hepatocellular Carcinoma. In: Journal of Virology, Bd. 92, Nr. 23, e01386-18

Scilabra, Simone D.; Pigoni, Martina; Pravata, Veronica; Schätzl, Tobias; Müller, Stephan A.; Troeberg, Linda und Lichtenthaler, Stefan F. (2018): Increased TIMP-3 expression alters the cellular secretome through dual inhibition of the metalloprotease ADAM10 and ligand-binding of the LRP-1 receptor. In: Scientific Reports, Bd. 8, 14697 [PDF, 3MB]

Herber, Julia; Njavro, Jasenka; Feederle, Regina; Schepers, Ute; Müller, Ulrike C.; Braese, Stefan; Müller, Stephan A. und Lichtenthaler, Stefan F. (2018): Click Chemistry-mediated Biotinylation Reveals a Function for the Protease BACE1 in Modulating the Neuronal Surface Glycoproteome. In: Molecular & Cellular Proteomics, Bd. 17, Nr. 8: S. 1487-1501

Causevic, Mirsada; Dominko, Kristina; Malnar, Martina; Vidatic, Lea; Cermak, Stjepko; Pigoni, Martina; Kuhn, Peer-Hendrik; Colombo, Alessio; Havas, Daniel; Flunkert, Stefanie; McDonald, Jessica; Gunnersen, Jenny M.; Hutter-Paier, Birgit; Tahirovic, Sabina; Windisch, Manfred; Krainc, Dimitri; Lichtenthaler, Stefan F. und Hecimovic, Silva (2018): BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains.
In: PLOS One 13(7), e0200344 [PDF, 74MB]

Hartlage-Ruebsamen, Maike; Bluhm, Alexandra; Piechotta, Anke; Linnert, Miriam; Rahfeld, Jens-Ulrich; Demuth, Hans-Ulrich; Lues, Inge; Kuhn, Peer-Hendrik; Lichtenthaler, Stefan F.; Rossner, Steffen und Hoefling, Corinna (2018): Immunohistochemical Evidence from APP-Transgenic Mice for Glutaminyl Cyclase as Drug Target to Diminish pE-Abeta Formation. In: Molecules, Bd. 23, Nr. 4, 924 [PDF, 48MB]

Lichtenthaler, Stefan F.; Lemberg, Marius K. und Fluhrer, Regina (2018): Proteolytic ectodomain shedding of membrane proteins in mammals-hardware, concepts, and recent developments. In: EMBO Journal, Bd. 37, Nr. 15, e99456

Duernberger, Yvonne; Liu, Shu; Riemschoss, Katrin; Paulsen, Lydia; Bester, Romina; Kuhn, Peer-Hendrik; Schölling, Manuel; Lichtenthaler, Stefan F. und Vorberg, Ina (2018): Prion Replication in the Mammalian Cytosol: Functional Regions within a Prion Domain Driving Induction, Propagation, and Inheritance. In: Molecular and Cellular Biology, Bd. 38, Nr. 15 [PDF, 8MB]

Colombo, Alessio; Hsia, Hung-En; Wang, Mengzhe; Kuhn, Peer-Hendrik; Brill, Monika S.; Canevazzi, Paolo; Feederle, Regina; Taveggia, Carla; Misgeld, Thomas und Lichtenthaler, Stefan F. (2018): Non-cell-autonomous function of DR6 in Schwann cell proliferation. In: EMBO Journal, Bd. 37, Nr. 7, e97390

Schlepckow, Kai; Kleinberger, Gernot; Fukumori, Akio; Feederle, Regina; Lichtenthaler, Stefan F.; Steiner, Harald und Haass, Christian

(2017): An Alzheimer-associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function. In: Embo Molecular Medicine, Bd. 9, Nr. 10: S. 1356-1365 [PDF, 1MB]

Scilabra, Simone D.; Yamamoto, Kazuhiro; Pigoni, Martina; Sakamoto, Kazuma; Müller, Stephan A.; Papadopoulou, Alkmini; Lichtenthaler, Stefan F.; Tröberg, Linda; Nagase, Hideaki und Kadomatsu, Kenji (2017): Dissecting the interaction between tissue inhibitor of metalloproteinases-3 (TIMP-3) and low density lipoprotein receptor-related protein-1 (LRP-1): Development of a "TRAP" to increase levels of TIMP-3 in the tissue. In: Matrix Biology, Bd. 59: S. 69-79

Bruch, Julius; Xu, Hong; Rösler, Thomas W.; Andrade, Anderson de; Kuhn, Peer-Hendrik; Lichtenthaler, Stefan F.; Arzberger, Thomas; Winklhofer, Konstanze F.; Müller, Ulrich und Höglinger, Günter U. (2017): PERK activation mitigates tau pathology in vitro and in vivo. In: Embo Molecular Medicine, Bd. 9, Nr. 3: S. 371-384

Kretner, Benedikt; Trambauer, Johannes; Fukumori, Akio; Mielke, Janina; Kuhn, Peer-Hendrik; Kremmer, Elisabeth; Giese, Armin; Lichtenthaler, Stefan F.; Haass, Christian

; Arzberger, Thomas und Steiner, Harald (2016): Generation and deposition of A43 by the virtually inactive presenilin-1 L435F mutant contradicts the presenilin loss-of-function hypothesis of Alzheimer's disease. In: Embo Molecular Medicine, Bd. 8, Nr. 5: S. 458-465

Kuhn, Peer-Hendrik; Colombo, Alessio Vittorio; Schusser, Benjamin; Dreymueller, Daniela; Wetzel, Sebastian; Schepers, Ute; Herber, Julia; Ludwig, Andreas; Kremmer, Elisabeth; Montag, Dirk; Müller, Ulrike; Schweizer, Michaels; Saftig, Paul; Bräse, Stefan und Lichtenthaler, Stefan F. (2016): Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function. In: eLife, Bd. 5, e12748 [PDF, 6MB]

Kretner, Benedikt; Trambauer, Johannes; Fukumori, Akio; Mielke, Janina; Kuhn, Peer-Hendrik; Kremmer, Elisabeth; Giese, Armin; Lichtenthaler, Stefan F.; Haass, Christian

Höfling, Corinna; Morawski, Markus; Zeitschel, Ulrike; Zanier, Elisa R.; Moschke, Katrin; Serdaroglu, Alperen; Canneva, Fabio; Hörsten, Stephan von; De Simoni, Maria-Grazia; Forloni, Gianluigi; Jäger, Carsten; Kremmer, Elisabeth; Rossner, Steffen; Lichtenthaler, Stefan F. und Kuhn, Peer-Hendrik (2016): Differential transgene expression patterns in Alzheimer mouse models revealed by novel human amyloid precursor protein-specific antibodies. In: Aging Cell, Bd. 15, Nr. 5: S. 953-963 [PDF, 1MB]

Laurent, Sarah A.; Hoffmann, Franziska S.; Kuhn, Peer-Hendrik; Cheng, Qingyu; Chu, Yuanyuan; Schmidt-Supprian, Marc; Hauck, Stefanie M.; Schuh, Elisabeth; Krumbholz, Markus; Ruebsamen, Heike; Wanngren, Johanna; Khademi, Mohsen; Olsson, Tomas; Alexander, Tobias; Hiepe, Falk; Pfister, Hans-Walter; Weber, Frank; Jenne, Dieter; Wekerle, Hartmut; Hohlfeld, Reinhard; Lichtenthaler, Stefan F. und Meinl, Edgar (2015): gamma-secretase directly sheds the survival receptor BCMA from plasma cells. In: Nature Communications, Bd. 6, 7333 [PDF, 1MB]

Hogl, Sebastian; Kuhn, Peer-Hendrik; Colombo, Alessio und Lichtenthaler, Stefan F. (2011): Determination of the proteolytic cleavage sites of the amyloid precursor-like protein 2 by the proteases ADAM10, BACE1 and γ-secretase.
In: PLOS ONE 6(6), e21337 [PDF, 2MB]

Leuchtenberger, Stefanie; Maler, Juan; Czirr, Eva; Ness, Julia; Lichtenthaler, Stefan F.; Esselmann, Hermann; Pietrzik, Claus U.; Wiltfang, Jens und Weggen, Sascha (2009): Nonsteroidal Anti-Inflammatory Drugs and Ectodomain Shedding of the Amyloid Precursor Protein. In: Neurodegenerative Diseases, Nr. 1-2: S. 1-8 [PDF, 377kB]

Naus, Silvia; Reipschläger, Simone; Wildeboer, Dirk; Lichtenthaler, Stefan F.; Mitterreiter, Stefan; Guan, Ziqiang; Moss, Marcia L. und Bartsch, Jörg W. (2006): Identification of candidate substrates for ectodomain shedding by the metalloprotease-disintegrin ADAM8. In: Biological Chemistry, Bd. 387, Nr. 3: S. 337-346 [PDF, 272kB]

Lichtenthaler, Stefan F. (2006): Ectodomain shedding of the amyloid precursor protein: Cellular control mechanisms and novel modifiers. In: Neurodegenerative Diseases, Nr. 4-5: S. 262-269 [PDF, 163kB]

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