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Anzahl der Publikationen: 112
Zeitschriftenartikel
Prapiadou, Savvina; Živković, Luka 
ORCID: https://orcid.org/0000-0002-9979-890X; Thorand, Barbara ORCID: https://orcid.org/0000-0002-8416-6440; George, Marc J. ORCID: https://orcid.org/0000-0003-0313-893X; Laan, Sander W. van der ORCID: https://orcid.org/0000-0001-6888-1404; Malik, Rainer ORCID: https://orcid.org/0000-0001-9212-2520; Herder, Christian ORCID: https://orcid.org/0000-0002-2050-093X; Koenig, Wolfgang ORCID: https://orcid.org/0000-0002-2064-9603; Ueland, Thor ORCID: https://orcid.org/0000-0001-5005-0784; Kleveland, Ola; Aukrust, Pål; Gullestad, Lars; Bernhagen, Jürgen ORCID: https://orcid.org/0000-0003-2996-2652; Pasterkamp, Gerard ORCID: https://orcid.org/0000-0001-5345-1022; Peters, Annette ORCID: https://orcid.org/0000-0001-6645-0985; Hingorani, Aroon D.; Rosand, Jonathan ORCID: https://orcid.org/0000-0002-1014-9138; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Anderson, Christopher D. ORCID: https://orcid.org/0000-0002-0053-2002 und Georgakis, Marios K. ORCID: https://orcid.org/0000-0003-3507-3659
(2024):
Proteogenomic Data Integration Reveals CXCL10 as a Potentially Downstream Causal Mediator for IL-6 Signaling on Atherosclerosis.
In: Circulation, Bd. 149, Nr. 9: S. 669-683
ORCID: https://orcid.org/0000-0002-9979-890X; Thorand, Barbara ORCID: https://orcid.org/0000-0002-8416-6440; George, Marc J. ORCID: https://orcid.org/0000-0003-0313-893X; Laan, Sander W. van der ORCID: https://orcid.org/0000-0001-6888-1404; Malik, Rainer ORCID: https://orcid.org/0000-0001-9212-2520; Herder, Christian ORCID: https://orcid.org/0000-0002-2050-093X; Koenig, Wolfgang ORCID: https://orcid.org/0000-0002-2064-9603; Ueland, Thor ORCID: https://orcid.org/0000-0001-5005-0784; Kleveland, Ola; Aukrust, Pål; Gullestad, Lars; Bernhagen, Jürgen ORCID: https://orcid.org/0000-0003-2996-2652; Pasterkamp, Gerard ORCID: https://orcid.org/0000-0001-5345-1022; Peters, Annette ORCID: https://orcid.org/0000-0001-6645-0985; Hingorani, Aroon D.; Rosand, Jonathan ORCID: https://orcid.org/0000-0002-1014-9138; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Anderson, Christopher D. ORCID: https://orcid.org/0000-0002-0053-2002 und Georgakis, Marios K. ORCID: https://orcid.org/0000-0003-3507-3659
(2024):
Proteogenomic Data Integration Reveals CXCL10 as a Potentially Downstream Causal Mediator for IL-6 Signaling on Atherosclerosis.
In: Circulation, Bd. 149, Nr. 9: S. 669-683
Kopczak, Anna; Stringer, Michael S.; Brink, Hilde van den; Kerkhofs, Danielle; Blair, Gordon W.; Dinther, Maud van; Reyes, Carmen Arteaga; Garcia, Daniela Jaime; Wartolowska, Karolina A.; Thrippleton, Michael J.; Kampaite, Agniete; Duering, Marco; Staals, Julie; Lesnik-Oberstein, Saskia; Muir, Keith W.; Middeke, Martin; Norrving, Bo; Bousser, Marie-Germaine; Mansmann, Ulrich ORCID: https://orcid.org/0000-0002-9955-8906; Rothwell, Peter M.; Doubal, Fergus N.; Oostenbrugge, Robert van; Biessels, Geert Jan; Webb, Alastair J. S.; Wardlaw, Joanna M.; Dichgans, Martin; Jaime Garcia, Daniela; Onkenhout, Laurien; André, Elisabeth; Kääb, Stefan ORCID: https://orcid.org/0000-0001-8824-3581; Anders, Hans-Joachim; Hack, Remco; Kaffe, Maria; Dewenter, Anna und Malik, Rainer
(2023):
Effect of blood pressure-lowering agents on microvascular function in people with small vessel diseases (TREAT-SVDs): a multicentre, open-label, randomised, crossover trial.
In: Lancet Neurology, Bd. 22, Nr. 11: S. 991-1004
ORCID: https://orcid.org/0000-0002-9955-8906; Rothwell, Peter M.; Doubal, Fergus N.; Oostenbrugge, Robert van; Biessels, Geert Jan; Webb, Alastair J. S.; Wardlaw, Joanna M.; Dichgans, Martin; Jaime Garcia, Daniela; Onkenhout, Laurien; André, Elisabeth; Kääb, Stefan ORCID: https://orcid.org/0000-0001-8824-3581; Anders, Hans-Joachim; Hack, Remco; Kaffe, Maria; Dewenter, Anna und Malik, Rainer
(2023):
Effect of blood pressure-lowering agents on microvascular function in people with small vessel diseases (TREAT-SVDs): a multicentre, open-label, randomised, crossover trial.
In: Lancet Neurology, Bd. 22, Nr. 11: S. 991-1004
Georgakis, Marios K. ORCID: https://orcid.org/0000-0003-3507-3659; Parodi, Livia ORCID: https://orcid.org/0000-0003-0605-2381; Frerich, Simon ORCID: https://orcid.org/0000-0002-8275-6113; Mayerhofer, Ernst; Tsivgoulis, Georgios ORCID: https://orcid.org/0000-0002-0640-3797; Pirruccello, James P.; Slowik, Agnieszka; Rundek, Tatjana; Malik, Rainer; Dichgans, Martin; Rosand, Jonathan und Anderson, Christopher D.
(2022):
Genetic Architecture of Stroke of Undetermined Source: Overlap with Known Stroke Etiologies and Associations with Modifiable Risk Factors.
In: Annals of Neurology, Bd. 91, Nr. 5: S. 640-651
[PDF, 1MB]
ORCID: https://orcid.org/0000-0003-3507-3659; Parodi, Livia ORCID: https://orcid.org/0000-0003-0605-2381; Frerich, Simon ORCID: https://orcid.org/0000-0002-8275-6113; Mayerhofer, Ernst; Tsivgoulis, Georgios ORCID: https://orcid.org/0000-0002-0640-3797; Pirruccello, James P.; Slowik, Agnieszka; Rundek, Tatjana; Malik, Rainer; Dichgans, Martin; Rosand, Jonathan und Anderson, Christopher D.
(2022):
Genetic Architecture of Stroke of Undetermined Source: Overlap with Known Stroke Etiologies and Associations with Modifiable Risk Factors.
In: Annals of Neurology, Bd. 91, Nr. 5: S. 640-651
[PDF, 1MB]
Rubinski, Anna; Frerich, Simon ORCID: https://orcid.org/0000-0002-8275-6113; Malik, Rainer; Franzmeier, Nicolai ORCID: https://orcid.org/0000-0001-9736-2283; Ramirez, Alfredo ORCID: https://orcid.org/0000-0003-4991-763X; Dichgans, Martin und Ewers, Michael ORCID: https://orcid.org/0000-0001-5231-1714
(2022):
Polygenic Effect on Tau Pathology Progression in Alzheimer's Disease.
In: Annals of Neurology, Bd. 93, Nr. 4: S. 819-829
[PDF, 1MB]
ORCID: https://orcid.org/0000-0002-8275-6113; Malik, Rainer; Franzmeier, Nicolai ORCID: https://orcid.org/0000-0001-9736-2283; Ramirez, Alfredo ORCID: https://orcid.org/0000-0003-4991-763X; Dichgans, Martin und Ewers, Michael ORCID: https://orcid.org/0000-0001-5231-1714
(2022):
Polygenic Effect on Tau Pathology Progression in Alzheimer's Disease.
In: Annals of Neurology, Bd. 93, Nr. 4: S. 819-829
[PDF, 1MB]
Mishra, Aniket; Malik, Rainer; Hachiya, Tsuyoshi; Jürgenson, Tuuli; Namba, Shinichi; Posner, Daniel C.; Kamanu, Frederick K.; Koido, Masaru; Le Grand, Quentin; Shi, Mingyang; He, Yunye; Georgakis, Marios K.; Caro, Ilana; Krebs, Kristi; Liaw, Yi-Ching; Vaura, Felix C.; Lin, Kuang; Winsvold, Bendik Slagsvold; Srinivasasainagendra, Vinodh; Parodi, Livia; Bae, Hee-Joon; Chauhan, Ganesh; Chong, Michael R.; Tomppo, Liisa; Akinyemi, Rufus; Roshchupkin, Gennady V.; Habib, Naomi; Jee, Yon Ho; Thomassen, Jesper Qvist; Abedi, Vida; Carcel-Marquez, Jara; Nygaard, Marianne; Leonard, Hampton L.; Yang, Chaojie; Yonova-Doing, Ekaterina; Knol, Maria J.; Lewis, Adam J.; Judy, Renae L.; Ago, Tetsuro; Amouyel, Philippe; Armstrong, Nicole D.; Bakker, Mark K.; Bartz, Traci M.; Bennett, David A.; Bis, Joshua C.; Bordes, Constance; Borte, Sigrid; Cain, Anael; Ridker, Paul M.; Cho, Kelly; Chen, Zhengming; Cruchaga, Carlos; Cole, John W.; Jager, Phil L. de; Cid, Rafael de; Endres, Matthias; Ferreira, Leslie E.; Geerlings, Mirjam I.; Gasca, Natalie C.; Gudnason, Vilmundur; Hata, Jun; He, Jing; Heath, Alicia K.; Ho, Yuk-Lam; Havulinna, Aki S.; Hopewell, Jemma C.; Hyacinth, Hyacinth I.; Inouye, Michael; Jacob, Mina A.; Jeon, Christina E.; Jern, Christina; Kamouchi, Masahiro; Keene, Keith L.; Kitazono, Takanari; Kittner, Steven J.; Konuma, Takahiro; Kumar, Amit; Lacaze, Paul; Launer, Lenore J.; Lee, Keon-Joo; Lepik, Kaido; Li, Jiang; Li, Liming; Manichaikul, Ani; Markus, Hugh S.; Marston, Nicholas A.; Meitinger, Thomas; Mitchell, Braxton D.; Montellano, Felipe A.; Morisaki, Takayuki; Mosley, Thomas H.; Nalls, Mike A.; Nordestgaard, Borge G.; O'Donnell, Martin J.; Okada, Yukinori; Onland-Moret, N. Charlotte; Ovbiagele, Bruce; Peters, Annette; Psaty, Bruce M.; Rich, Stephen S.; Rosand, Jonathan; Sabatine, Marc S.; Sacco, Ralph L.; Saleheen, Danish; Sandset, Else Charlotte; Salomaa, Veikko; Sargurupremraj, Muralidharan; Sasaki, Makoto; Satizabal, Claudia L.; Schmidt, Carsten O.; Shimizu, Atsushi; Smith, Nicholas L.; Sloane, Kelly L.; Sutoh, Yoichi; Sun, Yan V.; Tanno, Kozo; Tiedt, Steffen; Tatlisumak, Turgut; Torres-Aguila, Nuria P.; Tiwari, Hemant K.; Tregouet, David-Alexandre; Trompet, Stella; Tuladhar, Anil Man; Tybjaerg-Hansen, Anne; Vugt, Marion van; Vibo, Riina; Verma, Shefali S.; Wiggins, Kerri L.; Wennberg, Patrik; Woo, Daniel; Wilson, Peter W. F.; Xu, Huichun; Yang, Qiong; Yoon, Kyungheon; Bis, Joshua C.; Bis, Joshua C.; Lee, Jin-Moo; Cheng, Yu-Ching; Meschia, James F.; Chen, Wei Min; Sale, Michele M.; Zonderman, Alan B.; Evans, Michele K.; Wilson, James G.; Correa, Adolfo; Traylor, Matthew; Lewis, Cathryn M.; Carty, Cara L.; Reiner, Alexander; Haessler, Jeffrey; Langefeld, Carl D.; Gottesman, Rebecca F.; Yaffe, Kristine; Liu, Yong Mei; Kooperberg, Charles; Lange, Leslie A.; Furie, Karen L.; Arnett, Donna K.; Benavente, Oscar R.; Grewal, Raji P.; Peddareddygari, Leema Reddy; Kooperberg, Charles; Kooperberg, Charles; Hveem, Kristian; Lindstrom, Sara; Wang, Lu; Smith, Erin N.; Gordon, William; Hylckama Vlieg, Astrid van; de Andrade, Mariza; Brody, Jennifer A.; Pattee, Jack W.; Haessler, Jeffrey; Brumpton, Ben M.; Suchon, Pierre; Chen, Ming-Huei; Frazer, Kelly A.; Turman, Constance; Germain, Marine; MacDonald, James; Braekkan, Sigrid K.; Armasu, Sebastian M.; Pankratz, Nathan; Jackson, Rebecca D.; Nielsen, Jonas B.; Giulianini, Franco; Puurunen, Marja K.; Ibrahim, Manal; Heckbert, Susan R.; Bammler, Theo K.; McCauley, Bryan M.; Taylor, Kent D.; Pankow, James S.; Reiner, Alexander P.; Gabrielsen, Maiken E.; Deleuze, Jean-Francois; O'Donnell, Chris J.; Kim, Jihye; McKnight, Barbara; Kraft, Peter; Hansen, John-Bjarne; Rosendaal, Frits R.; Heit, John A.; Tang, Weihong; Morange, Pierre-Emmanuel; Johnson, Andrew D.; Kabrhel, Christopher; Dijk, Ewoud J. van; Dijk, Ewoud J. van; Koudstaal, Peter J.; Luijckx, Gert-Jan; Nederkoorn, Paul J.; Oostenbrugge, Robert J. van; Visser, Marieke C.; Wermer, Marieke J. H.; Kappelle, L. Jaap; Esko, Tonu; Esko, Tonu; Metspalu, Andres; Magi, Reedik; Nelis, Mari; Irvin, Marguerite R.; Irvin, Marguerite R.; de Leeuw, Frank-Erik; Levi, Christopher R.; Maguire, Jane; Jimenez-Conde, Jordi; Sharma, Pankaj; Sudlow, Cathie L. M.; Rannikmae, Kristiina; Schmidt, Reinhold; Slowik, Agnieszka; Pera, Joanna; Thijs, Vincent N. S.; Lindgren, Arne G.; Ilinca, Andreea; Melander, Olle; Engstrom, Gunnar; Rexrode, Kathryn M.; Rothwell, Peter M.; Stanne, Tara M.; Johnson, Julie A.; Danesh, John; Butterworth, Adam S.; Heitsch, Laura; Boncoraglio, Giorgio B.; Kubo, Michiaki; Pezzini, Alessandro; Rolfs, Arndt; Giese, Anne-Katrin; Weir, David; Jackson, Rebecca D.; Ross, Owen A.; Lemmons, Robin; Soderholm, Martin; Cushman, Mary; Jood, Katarina; McDonough, Caitrin W.; Bell, Steven; Linkohr, Birgit; Lee, Tsong-Hai; Putaala, Jukka; Anderson, Christopher D.; Anderson, Christopher D.; Lopez, Oscar L.; Jian, Xueqiu; Schminke, Ulf; Cullell, Natalia; Delgado, Pilar; Ibanez, Laura; Krupinski, Jerzy; Lioutas, Vasileios; Matsuda, Koichi; Montaner, Joan; Muino, Elena; Roquer, Jaume; Sarnowski, Chloe; Sattar, Naveed; Sibolt, Gerli; Teumer, Alexander; Rutten-Jacobs, Loes; Kanai, Masahiro; Giese, Anne-Katrin; Gretarsdottir, Solveig; Rost, Natalia S.; Yusuf, Salim; Almgren, Peter; Ay, Hakan; Bevan, Steve; Brown, Robert D.; Carrera, Caty; Buring, Julie E.; Chen, Wei-Min; Cotlarciuc, Ioana; de Bakker, Paul I. W.; DeStefano, Anita L.; Hoed, Marcel den; Duan, Qing; Engelter, Stefan T.; Falcone, Guido J.; Gottesman, Rebecca F.; Gustafsson, Stefan; Hassan, Ahamad; Holliday, Elizabeth G.; Howard, George; Hsu, Fang-Chi; Ingelsson, Erik; Harris, Tamara B.; Kissela, Brett M.; Kleindorfer, Dawn O.; Langenberg, Claudia; Lemmens, Robin; Leys, Didier; Lin, Wei-Yu; Lorentzen, Erik; Magnusson, Patrik K.; McArdle, Patrick F.; Pulit, Sara L.; Rice, Kenneth; Sakaue, Saori; Sapkota, Bishwa R.; Tanislav, Christian; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Tzourio, Christophe; Duijn, Cornelia M. van; Walters, Matthew; Wareham, Nicholas J.; Amin, Najaf; Aparicio, Hugo J.; Attia, John; Beiser, Alexa S.; Berr, Claudine; Bustamante, Mariana; Caso, Valeria; Choi, Seung Hoan; Chowhan, Ayesha; Dartigues, Jean-Francois; Delavaran, Hossein; Dorr, Marcus; Ford, Ian; Gurpreet, Wander S.; Hamsten, Anders; Hozawa, Atsushi; Ingelsson, Martin; Iwasaki, Motoki; Kaffashian, Sara; Kalra, Lalit; Kjartansson, Olafur; Kloss, Manja; Labovitz, Daniel L.; Laurie, Cathy C.; Li, Linxin; Lind, Lars; Lindgren, Cecilia M.; Makoto, Hirata; Minegishi, Naoko; Morris, Andrew P.; Müller-Nurasyid, Martina; Norrving, Bo; Ogishima, Soichi; Parati, Eugenio A.; Pedersen, Nancy L.; Perola, Markus; Jousilahti, Pekka; Pileggi, Silvana; Rabionet, Raquel; Riba-Llena, Iolanda; Ribases, Marta; Romero, Jose R.; Rudd, Anthony G.; Sarin, Antti-Pekka; Sarju, Ralhan; Satoh, Mamoru; Sawada, Norie; Sigurdsson, Asgeir; Smith, Albert; Stine, O. Colin; Stott, David J.; Strauch, Konstantin; Takai, Takako; Tanaka, Hideo; Touze, Emmanuel; Tsugane, Shoichiro; Uitterlinden, Andre G.; Valdimarsson, Einar M.; Lee, Sven J. van der; Wakai, Kenji; Williams, Stephen R.; Wolfe, Charles D. A.; Wong, Quenna; Yamaji, Taiki; Sanghera, Dharambir K.; Stefansson, Kari; Taylor, Kent D.; Martinez-Majander, Nicolas; Sobue, Kenji; Soriano-Tarraga, Carolina; Volzke, Henry; Akpa, Onoja; Akpa, Onoja; Sarfo, Fred S.; Akpalu, Albert; Obiako, Reginald; Wahab, Kolawole; Osaigbovo, Godwin; Owolabi, Lukman; Komolafe, Morenikeji; Jenkins, Carolyn; Arulogun, Oyedunni; Ogbole, Godwin; Adeoye, Abiodun M.; Akinyemi, Joshua; Agunloye, Atinuke; Fakunle, Adekunle G.; Uvere, Ezinne; Olalere, Abimbola; Adebajo, Olayinka J.; Chen, Junshi; Chen, Junshi; Clarke, Robert; Collins, Rory; Guo, Yu; Wang, Chen; Lv, Jun; Peto, Richard; Chen, Yiping; Fairhurst-Hunter, Zammy; Hill, Michael; Pozarickij, Alfred; Schmidt, Dan; Stevens, Becky; Turnbull, Iain; Yu, Canqing; Le Grand, Quentin; Le Grand, Quentin; Ferreira, Leslie E.; Nagai, Akiko; Nagai, Akiko; Murakami, Yoishinori; Geerlings, Mirjam I.; Geerlings, Mirjam I.; Gasca, Natalie C.; Gudnason, Vilmundur; Vugt, Marion van; Gottesman, Rebecca F.; Shiroma, Eric J.; Sigurdsson, Sigurdur; Ghanbari, Mohsen; Boerwinkle, Eric; Beiser, Alexa S.; Fongang, Bernard; Wang, Ruiqi; Ikram, Mohammad K.; Volker, Uwe; de Jager, Phil L.; de Jager, Phil L.; de Cid, Rafael; Nordestgaard, Borge G.; Sargurupremraj, Muralidharan; Verma, Shefali S.; de Laat, Karlijn F.; de Laat, Karlijn F.; Norden, Anouk G. W. van; de Kort, Paul L.; Vermeer, Sarah E.; Brouwers, Paul J. A. M.; Gons, Rob A. R.; Nederkoorn, Paul J.; den Heijer, Tom; Dijk, Gert W. van; Rooij, Frank G. W. van; Aamodt, Anne H.; Aamodt, Anne H.; Skogholt, Anne H.; Brumpton, Ben M.; Willer, Cristen J.; Heuch, Ingrid; Hagen, Knut; Fritsche, Lars G.; Pedersen, Linda M.; Gabrielsen, Maiken E.; Ellekjaer, Hanne; Zhou, Wei; Martinsen, Amy E.; Kristoffersen, Espen S.; Nielsen, Jonas B.; Hveem, Kristian; Thomas, Laurent F.; Kleinschnitz, Christoph; Kleinschnitz, Christoph; Frantz, Stefan; Ungethum, Kathrin; Gallego-Fabrega, Cristina; Gallego-Fabrega, Cristina; Lledos, Miquel; Llucia-Carol, Laia; Sobrino, Tomas; Campos, Francisco; Castillo, Jose; Freijo, Marimar; Arenillas, Juan Francisco; Obach, Victor; Alvarez-Sabin, Jose; Molina, Carlos A.; Ribo, Marc; Munoz-Narbona, Lucia; Lopez-Cancio, Elena; Millan, Monica; Diaz-Navarro, Rosa; Vives-Bauza, Cristofol; Serrano-Heras, Gemma; Segura, Tomas; Delgado, Pilar; Dhar, Rajat; Delgado-Mederos, Raquel; Prats-Sanchez, Luis; Camps-Renom, Pol; Blay, Natalia; Sumoy, Lauro; Marti-Fabregas, Joan; Schnohr, Peter; Schnohr, Peter; Jensen, Gorm B.; Benn, Marianne; Afzal, Shoaib; Kamstrup, Pia R.; Setten, Jessica van; Laan, Sander W. van der; Vonk, Jet M. J.; Kim, Bong-Jo; Kim, Bong-Jo; Curtze, Sami; Curtze, Sami; Tiainen, Marjaana; Kinnunen, Janne; Menon, Vilas; Menon, Vilas; Sung, Yun Ju; Yang, Chengran; Saillour-Glenisson, Florence; Gravel, Simon; Onland-Moret, N. Charlotte; Onland-Moret, N. Charlotte; Heath, Alicia K.; Millwood, Iona Y.; Gieger, Christian; Ninomiya, Toshiharu; Grabe, Hans J.; Jukema, J. Wouter; Rissanen, Ina L.; Strbian, Daniel; Kim, Young Jin; Chen, Pei-Hsin; Mayerhofer, Ernst; Howson, Joanna M. M.; Irvin, Marguerite R.; Adams, Hieab; Wassertheil-Smoller, Sylvia; Christensen, Kaare; Ikram, Mohammad A.; Rundek, Tatjana; Worrall, Bradford B.; Lathrop, G. Mark; Riaz, Moeen; Simonsick, Eleanor M.; Korv, Janika; Franca, Paulo H. C.; Zand, Ramin; Prasad, Kameshwar; Frikke-Schmidt, Ruth; de Leeuw, Frank-Erik; Liman, Thomas; Haeusler, Karl Georg; Ruigrok, Ynte M.; Heuschmann, Peter Ulrich; Longstreth, W. T.; Jung, Keum Ji; Bastarache, Lisa; Pare, Guillaume; Damrauer, Scott M.; Chasman, Daniel I.; Rotter, Jerome I.; Anderson, Christopher D.; Zwart, John-Anker; Niiranen, Teemu J.; Fornage, Myriam; Liaw, Yung-Po; Seshadri, Sudha; Fernandez-Cadenas, Israel; Walters, Robin G.; Ruff, Christian T.; Owolabi, Mayowa O.; Huffman, Jennifer E.; Milani, Lili; Kamatani, Yoichiro; Dichgans, Martin und Debette, Stephanie
(2022):
Stroke genetics informs drug discovery and risk prediction across ancestries.
In: Nature, Bd. 611, Nr. 7934: S. 115-123
Hautakangas, Heidi; Winsvold, Bendik S.; Ruotsalainen, Sanni E.; Bjornsdottir, Gyda; Harder, Aster V. E.; Kogelman, Lisette J. A.; Thomas, Laurent F.; Noordam, Raymond; Benner, Christian; Gormley, Padhraig; Artto, Ville; Banasik, Karina; Bjornsdottir, Anna; Boomsma, Dorret I.; Brumpton, Ben M.; Burgdorf, Kristoffer Solvsten; Buring, Julie E.; Chalmer, Mona Ameri; Boer, Irene de; Dichgans, Martin; Erikstrup, Christian; Farkkila, Markus; Garbrielsen, Maiken Elvestad; Ghanbari, Mohsen; Hagen, Knut; Happola, Paavo; Hottenga, Jouke-Jan; Hrafnsdottir, Maria G.; Hveem, Kristian; Johnsen, Marianne Bakke; Kahonen, Mika; Kristoffersen, Espen S.; Kurth, Tobias; Lehtimaki, Terho; Lighart, Lannie; Magnusson, Sigurdur H.; Malik, Rainer; Pedersen, Ole Birger; Pelzer, Nadine; Penninx, Brenda W. J. H.; Ran, Caroline; Ridker, Paul M.; Rosendaal, Frits R.; Sigurdardottir, Gudrun R.; Skogholt, Anne Heidi; Sveinsson, Olafur A.; Thorgeirsson, Thorgeir E.; Ullum, Henrik; Vijfhuizen, Lisanne S.; Widen, Elisabeth; Dijk, Ko Willems van; Aromaa, Arpo; Belin, Andrea Carmine; Freilinger, Tobias; Ikram, M. Arfan; Jarvelin, Marjo-Riitta; Raitakari, Olli T.; Terwindt, Gisela M.; Kallela, Mikko; Wessman, Maija; Olesen, Jes; Chasman, Daniel I.; Nyholt, Dale R.; Stefansson, Hreinn; Stefansson, Kari; Maagdenberg, Arn M. J. M. van den; Hansen, Thomas Folkmann; Ripatti, Samuli; Zwart, John-Anker; Palotie, Aarno und Pirinen, Matti
(2022):
Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles.
In: Nature Genetics, Bd. 54, Nr. 2: S. 152-160
Frerich, Simon; Malik, Rainer; Georgakis, Marios K.; Sinner, Moritz F.; Kittner, Steven J.; Mitchell, Braxton D. und Dichgans, Martin
(2022):
Cardiac Risk Factors for Stroke: A Comprehensive Mendelian Randomization Study.
In: Stroke, Bd. 53, Nr. 4, E130-E135
Georgakis, Marios K. und Malik, Rainer
(2022):
Integrating Genetics Into Stroke Research and Care.
In: Stroke, Bd. 53, Nr. 12, E527-E530
Parodi, Livia; Myserlis, Evangelos Pavlos; Chung, Jaeyoon; Georgakis, Marios K.; Mayerhofer, Ernst; Henry, Jonathan; Montgomery, Bailey E.; Moy, Mandy; Xu, Huichun; Malik, Rainer; Langefeld, Carl D.; Dichgans, Martin; Woo, Daniel; Rosand, Jonathan und Anderson, Christopher D.
(2022):
Shared genetic background between SARS-CoV-2 infection and large artery stroke.
In: International Journal of Stroke, Bd. 17, Nr. 8: S. 873-880
Daghals, Iyas; Sargurupremraj, Muralidharan; Danning, Rebecca; Gormley, Padhraig; Malik, Rainer; Amouyel, Philippe; Metso, Tiina; Pezzini, Alessandro; Kurth, Tobias; Debette, Stephanie und Chasman, Daniel
(2022):
Migraine, Stroke, and Cervical Arterial Dissection Shared Genetics for a Triad of Brain Disorders With Vascular Involvement.
In: Neurology - Genetics, Bd. 8, Nr. 1, e653
Ferguson, Amy Christina; Thrippleton, Sophie; Henshall, David; Whittaker, Ed; Conway, Bryan; MacLeod, Malcolm; Malik, Rainer; Rawlik, Konrad; Tenesa, Albert; Sudlow, Cathie und Rannikmae, Kristiina
(2022):
Frequency and Phenotype Associations of Rare Variants in 5 Monogenic Cerebral Small Vessel Disease Genes in 200,000 UK Biobank Participants.
In: Neurology - Genetics, Bd. 8, Nr. 5, e200015
Jaworek, Thomas; Xu, Huichun; Gaynor, Brady J.; Cole, John W.; Rannikmae, Kristiina; Stanne, Tara M.; Tomppo, Liisa; Abedi, Vida; Amouyel, Philippe; Armstrong, Nicole D.; Attia, John; Bell, Steven; Benavente, Oscar R.; Boncoraglio, Giorgio B.; Butterworth, Adam; Carcel-Marquez, Jara; Chen, Zhengming; Chong, Michael; Cruchaga, Carlos; Cushman, Mary; Danesh, John; Debette, Stephanie; Duggan, David J.; Durda, Jon Peter; Engstrom, Gunnar; Enzinger, Chris; Faul, Jessica D.; Fecteau, Natalie S.; Fernandez-Cadenas, Israel; Gieger, Christian; Giese, Anne-Katrin; Grewal, Raji P.; Grittner, Ulrike; Havulinna, Aki S.; Heitsch, Laura; Hochberg, Marc C.; Holliday, Elizabeth; Hu, Jie; Ilinca, Andreea; Irvin, Marguerite R.; Jackson, Rebecca D.; Jacob, Mina A.; Rabionet, Raquel; Jimenez-Conde, Jordi; Johnson, Julie A.; Kamatani, Yoichiro; Kardia, Sharon L. R.; Koido, Masaru; Kubo, Michiaki; Lange, Leslie; Lee, Jin-Moo; Lemmens, Robin; Levi, Christopher R.; Li, Jiang; Li, Liming; Lin, Kuang; Lopez, Haley; Luke, Sothear; Maguire, Jane; McArdle, Patrick F.; McDonough, Caitrin W.; Meschia, James F.; Metso, Tiina; Müller-Nurasyid, Martina; O'Connor, Timothy D.; O'Donnell, Martin; Peddareddygari, Leema R.; Pera, Joanna; Perry, James A.; Peters, Annette; Putaala, Jukka; Ray, Debashree; Rexrode, Kathryn; Ribases, Marta; Rosand, Jonathan; Rothwell, Peter M.; Rundek, Tatjana; Ryan, Kathleen A.; Sacco, Ralph L.; Salomaa, Veikko; Sanchez-Mora, Cristina; Schmidt, Reinhold; Sharma, Pankaj; Slowik, Agnieszka; Smith, Jennifer A.; Smith, Nicholas L.; Wassertheil-Smoller, Sylvia; Soderholm, Martin; Stine, O. Colin; Strbian, Daniel; Sudlow, Cathie L. M.; Tatlisumak, Turgut; Terao, Chikashi; Thijs, Vincent; Torres-Aguila, Nuria P.; Tregouet, David-Alexandre; Tuladhar, Anil M.; Veldink, Jan H.; Walters, Robin G.; Weir, David R.; Woo, Daniel; Worrall, Bradford B.; Hong, Charles C.; Ross, Owen A.; Zand, Ramin; Leeuw, Frank-Erik de; Lindgren, Arne G.; Pare, Guillaume; Anderson, Christopher D.; Markus, Hugh S.; Jern, Christina; Malik, Rainer; Dichgans, Martin; Mitchell, Braxton D. und Kittner, Steven J.
(2022):
Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke.
In: Neurology, Bd. 99, Nr. 16, E1738-E1754
Rannikmae, Kristiina; Rawlik, Konrad; Ferguson, Amy C.; Avramidis, Nikos; Jiang, Muchen; Pirastu, Nicola; Shen, Xia; Davidson, Emma; Woodfield, Rebecca; Malik, Rainer; Dichgans, Martin; Tenesa, Albert und Sudlow, Cathie
(2022):
Physician-Confirmed and Administrative Definitions of Stroke in UK Biobank Reflect the Same Underlying Genetic Trait.
In: Frontiers in Neurology, Bd. 12, 787107
Mayerhofer, Ernst; Malik, Rainer; Parodi, Livia; Burgess, Stephen; Harloff, Andreas; Dichgans, Martin; Rosand, Jonathan; Anderson, Christopher D. und Georgakis, Marios K.
(2022):
Genetically predicted on-statin LDL response is associated with higher intracerebral haemorrhage risk.
In: Brain, Bd. 145, Nr. 8: S. 2677-2686
Georgakis, Marios K.; Malik, Rainer; Burgess, Stephen und Dichgans, Martin
(2022):
Additive Effects of Genetic Interleukin-6 Signaling Downregulation and Low-Density Lipoprotein Cholesterol Lowering on Cardiovascular Disease: A 2x2 Factorial Mendelian Randomization Analysis.
In: Journal of the American Heart Association, Bd. 11, Nr. 1, e023277
Georgakis, Marios K.; Malik, Rainer; Richardson, Tom G.; Howson, Joanna M. M.; Anderson, Christopher D.; Burgess, Stephen; Hovingh, G. Kees; Dichgans, Martin und Gill, Dipender
(2022):
Associations of genetically predicted IL-6 signaling with cardiovascular disease risk across population subgroups.
In: BMC Medicine, Bd. 20, Nr. 1, 245
Taylor-Bateman, Victoria; Gill, Dipender; Georgakis, Marios; Malik, Rainer; Munroe, Patricia und Traylor, Matthew
(2022):
Cardiovascular Risk Factors and MRI Markers of Cerebral Small Vessel Disease A Mendelian Randomization Study.
In: Neurology, Bd. 98, Nr. 4, E343-E351
Marchis, Gian Marco De; Dittrich, Tolga D.; Malik, Rainer; Zietz, Annaelle V.; Kriemler, Lilian F.; Ference, Brian A.; Dichgans, Martin und Georgakis, Marios K.
(2022):
Genetic proxies for PCSK9 inhibition associate with lipoprotein(a): Effects on coronary artery disease and ischemic stroke.
In: Atherosclerosis, Bd. 361: S. 41-46
Kopczak, Anna; Schindler, Andreas; Sepp, Dominik; Bayer-Karpinska, Anna; Malik, Rainer; Koch, Mia L.; Zeller, Julia; Strecker, Christoph; Janowitz, Daniel; Wollenweber, Frank A.; Hempel, Johann-Martin; Böckh-Behrens, Tobias; Cyran, Clemens C.; Helck, Andreas; Harloff, Andreas; Ziemann, Ulf; Poli, Sven; Poppert, Holger; Saam, Tobias und Dichgans, Martin
(2022):
Complicated Carotid Artery Plaques and Risk of Recurrent Ischemic Stroke or TIA.
In: Journal of the American College of Cardiology, Bd. 79, Nr. 22: S. 2189-2199
Fani, Lana ORCID: https://orcid.org/0000-0003-4961-5631; Georgakis, Marios; Ikram, M. Arfan ORCID: https://orcid.org/0000-0003-0372-8585; Ikram, M. Kamran; Malik, Rainer und Dichgans, Martin
(17. Mai 2021):
Circulating biomarkers of immunity and inflammation, risk of Alzheimer’s disease, and hippocampal volume: a Mendelian randomization study.
In: Translational Psychiatry, Bd. 11, 291
[PDF, 875kB]
ORCID: https://orcid.org/0000-0003-4961-5631; Georgakis, Marios; Ikram, M. Arfan ORCID: https://orcid.org/0000-0003-0372-8585; Ikram, M. Kamran; Malik, Rainer und Dichgans, Martin
(17. Mai 2021):
Circulating biomarkers of immunity and inflammation, risk of Alzheimer’s disease, and hippocampal volume: a Mendelian randomization study.
In: Translational Psychiatry, Bd. 11, 291
[PDF, 875kB]
Neitzel, Julia; Franzmeier, Nicolai; Rubinski, Anna; Dichgans, Martin; Brendel, Matthias ORCID: https://orcid.org/0000-0002-9247-2843; Malik, Rainer und Ewers, Michael
(2021):
KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer's disease.
In: Nature Communications, Bd. 12, Nr. 1, 3825
[PDF, 1MB]
ORCID: https://orcid.org/0000-0002-9247-2843; Malik, Rainer und Ewers, Michael
(2021):
KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer's disease.
In: Nature Communications, Bd. 12, Nr. 1, 3825
[PDF, 1MB]
Burgess, Stephen; Malik, Rainer; Liu, Bowen; Mason, Amy M.; Georgakis, Marios K.; Dichgans, Martin und Gill, Dipender
(2021):
Dose-response relationship between genetically proxied average blood glucose levels and incident coronary heart disease in individuals without diabetes mellitus.
In: Diabetologia, Bd. 64, Nr. 4: S. 845-849
Fani, Lana; Georgakis, Marios K.; Ikram, M. Arfan; Ikram, M. Kamran; Malik, Rainer und Dichgans, Martin
(2021):
Circulating biomarkers of immunity and inflammation, risk of Alzheimer's disease, and hippocampal volume: a Mendelian randomization study.
In: Translational Psychiatry, Bd. 11, Nr. 1, 291
Georgakis, Marios K.; Harshfield, Eric L.; Malik, Rainer; Franceschini, Nora; Langenberg, Claudia; Wareham, Nicholas J.; Markus, Hugh S. und Dichgans, Martin
(2021):
Diabetes Mellitus, Glycemic Traits, and Cerebrovascular Disease A Mendelian Randomization Study.
In: Neurology, Bd. 96, Nr. 13, E1732-E1742
Harshfield, Eric L.; Georgakis, Marios K.; Malik, Rainer; Dichgans, Martin und Markus, Hugh S.
(2021):
Modifiable Lifestyle Factors and Risk of Stroke A Mendelian Randomization Analysis.
In: Stroke, Bd. 52, Nr. 3: S. 931-936
Konieczny, Marek J.; Dewenter, Anna; Telgte, Annemieke ter; Gesierich, Benno; Wiegertjes, Kim; Finsterwalder, Sofia; Kopczak, Anna; Huebner, Mathias; Malik, Rainer; Tuladhar, Anil M.; Marques, Jose P.; Norris, David G.; Koch, Alexandra; Dietrich, Olaf; Ewers, Michael; Schmidt, Reinhold; Leeuw, Frank-Erik de und Duering, Marco
(2021):
Multi-shell Diffusion MRI Models for White Matter Characterization in Cerebral Small Vessel Disease.
In: Neurology, Bd. 96, Nr. 5, E698-E708
Levin, Michael G.; Zuber, Verena; Walker, Venexia M.; Klarin, Derek; Lynch, Julie; Malik, Rainer; Aday, Aaron W.; Bottolo, Leonardo; Pradhan, Aruna D.; Dichgans, Martin; Chang, Kyong-Mi; Rader, Daniel J.; Tsao, Philip S.; Voight, Benjamin F.; Gill, Dipender; Burgess, Stephen und Damrauer, Scott M.
(2021):
Prioritizing the Role of Major Lipoproteins and Subfractions as Risk Factors for Peripheral Artery Disease.
In: Circulation, Bd. 144, Nr. 5: S. 353-364
Malik, Rainer; Beaufort, Nathalie; Frerich, Simon; Gesierich, Benno; Georgakis, Marios K.; Rannikmae, Kristiina; Ferguson, Amy C.; Haffner, Christof; Traylor, Matthew; Ehrmann, Michael; Sudlow, Cathie L. M. und Dichgans, Martin
(2021):
Whole-exome sequencing reveals a role of HTRA1 and EGFL8 in brain white matter hyperintensities.
In: Brain, Bd. 144: S. 2670-2682
Malik, Rainer; Georgakis, Marios K.; Neitzel, Julia; Rannikmae, Kristiina; Ewers, Michael; Seshadri, Sudha; Sudlow, Cathie L. M. und Dichgans, Martin
(2021):
Midlife vascular risk factors and risk of incident dementia: Longitudinal cohort and Mendelian randomization analyses in the UK Biobank.
In: Alzheimers & Dementia, Bd. 17, Nr. 9: S. 1422-1431
Malik, Rainer; Georgakis, Marios K.; Vujkovic, Marijana; Damrauer, Scott M.; Elliott, Paul; Karhunen, Ville; Giontella, Alice; Fava, Cristiano; Hellwege, Jacklyn N.; Shuey, Megan M.; Edwards, Todd L.; Rogne, Tormod; Asvold, Bjorn O.; Brumpton, Ben M.; Burgess, Stephen; Dichgans, Martin und Gill, Dipender
(2021):
Relationship Between Blood Pressure and Incident Cardiovascular Disease Linear and Nonlinear Mendelian Randomization Analyses.
In: Hypertension, Bd. 77, Nr. 6: S. 2004-2013
Neitzel, Julia; Franzmeier, Nicolai; Rubinski, Anna; Dichgans, Martin; Brendel, Matthias; Malik, Rainer und Ewers, Michael
(2021):
KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer's disease.
In: Nature Communications, Bd. 12, Nr. 1, 3825
Roth, Stefan; Yang, Jun; Cramer, Julia; Malik, Rainer und Liesz, Arthur
(2021):
Detection of cytokine-induced sickness behavior after ischemic stroke by an optimized behavioral assessment battery.
In: Brain Behavior and Immunity, Bd. 91: S. 668-672
Traylor, Matthew; Malik, Rainer; Gesierich, Benno und Dichgans, Martin
(2021):
The BS variant of C4 protects against age-related loss of white matter microstructural integrity.
In: Brain, Bd. 145, Nr. 1: S. 295-304
Weisheit, Isabel; Kroeger, Joseph A.; Malik, Rainer; Wefers, Benedikt; Lichtner, Peter; Wurst, Wolfgang; Dichgans, Martin und Paquet, Dominik
(2021):
Simple and reliable detection of CRISPR-induced on-target effects by qgPCR and SNP genotyping.
In: Nature Protocols, Bd. 16, Nr. 3: S. 1714-1739
Asare, Y.; Campbell-James, T. A.; Bokov, Y.; Yu, L. L.; Prestel, M.; El Bounkari, O.; Roth, S.; Megens, Remco; Straub, T.; Thomas, K.; Yan, G.; Schneider, M.; Ziesch, N.; Tiedt, Steffen; Silvestre-Roig, Carlos; Braster, Quinte; Huang, Y.; Schneider, M.; Malik, Rainer; Haffner, Christof; Liesz, Arthur; Soehnlein, Oliver; Bernhagen, Jürgen und Dichgans, Martin
(17. Juni 2020):
Histone Deacetylase 9 Activates IKK to Regulate Atherosclerotic Plaque Vulnerability.
In: Circulation Research
[PDF, 18MB]
Georgakis, Marios K.; Malik, Rainer; Gillor, D.; Franceschini, Nora; Sudlow, Cathie L. M. und Dichgans, Martin
(17. Juni 2020):
Interleukin-6 Signaling Effects on Ischemic Stroke and Other Cardiovascular Outcomes: A Mendelian Randomization Study.
In: Circulation: Genomic and Precision Medicine, Bd. 13, Nr. 3
[PDF, 273kB]
Georgakis, Marios K.; Malik, Rainer; Anderson, Christopher D.; Parhofer, Klaus G.; Hopewell, Jemma C. und Dichgans, Martin
(1. Februar 2020):
Genetic determinants of blood lipids and cerebral small vessel disease: role of high-density lipoprotein cholesterol.
In: Brain, Bd. 143, Nr. 2: S. 597-610
[PDF, 1MB]
Georgakis, Marios K.; de Lemos, James A.; Ayers, Colby; Wang, Biqi; Bjorkbacka, Harry; Pana, Tiberiu A.; Thorand, Barbara; Sun, Caroline; Fani, Lana; Malik, Rainer; Dupuis, Josee; Engstrom, Gunnar; Orho-Melander, Marju; Melander, Olle; Boekholdt, S. Matthijs; Zierer, Astrid; Elhadad, Mohamed A.; König, Wolfgang; Herder, Christian; Hoogeveen, Ron C.; Kavousi, Maryam; Ballantyne, Christie M.; Peters, Annette ORCID: https://orcid.org/0000-0001-6645-0985; Myint, Phyo K.; Nilsson, Jan; Benjamin, Emelia J. und Dichgans, Martin
(2020):
Association of Circulating Monocyte Chemoattractant Protein-1 Levels With Cardiovascular Mortality A Meta-analysis of Population-Based Studies.
In: Jama Cardiology, Bd. 6, Nr. 5: S. 587-592
ORCID: https://orcid.org/0000-0001-6645-0985; Myint, Phyo K.; Nilsson, Jan; Benjamin, Emelia J. und Dichgans, Martin
(2020):
Association of Circulating Monocyte Chemoattractant Protein-1 Levels With Cardiovascular Mortality A Meta-analysis of Population-Based Studies.
In: Jama Cardiology, Bd. 6, Nr. 5: S. 587-592
Marini, Sandro; Merino, Jordi; Montgomery, Bailey E.; Malik, Rainer; Sudlow, Catherine L.; Dichgans, Martin; Florez, Jose C.; Rosand, Jonathan; Gill, Dipender und Anderson, Christopher D.
(2020):
Mendelian Randomization Study of Obesity and Cerebrovascular Disease.
In: Annals of Neurology, Bd. 87, Nr. 4: S. 516-524
Weisheit, Isabel; Kroeger, Joseph A.; Malik, Rainer; Klimmt, Julien; Crusius, Dennis; Dannert, Angelika; Dichgans, Martin und Paquet, Dominik
(2020):
Detection of Deleterious On-Target Effects after HDR-Mediated CRISPR Editing.
In: Cell Reports, Bd. 31, Nr. 8, 107689
Kopczak, Anna; Schindler, Andreas; Bayer-Karpinska, Anna; Koch, Mia L.; Sepp, Dominik; Zeller, Julia; Strecker, Christoph; Hempel, Johann-Martin; Yuan, Chun; Malik, Rainer; Wollenweber, Frank A.; Boeckh-Behrens, Tobias; Cyran, Clemens C.; Helck, Andreas; Harloff, Andreas; Ziemann, Ulf; Poli, Sven; Poppert, Holger; Dichgans, Martin und Saam, Tobias
(2020):
Complicated Carotid Artery Plaques as a Cause of Cryptogenic Stroke.
In: Journal of the American College of Cardiology, Bd. 76, Nr. 19: S. 2212-2222
Berg, Joanna von; Laan, Sander W. van der; McArdle, Patrick F.; Malik, Rainer; Kittner, Steven J.; Mitchell, Braxton D.; Worrall, Bradford B.; Ridder, Jeroen de und Pulit, Sara L.
(2020):
Alternate approach to stroke phenotyping identifies a genetic risk locus for small vessel stroke.
In: European Journal of Human Genetics, Bd. 28, Nr. 7: S. 963-972
Bakker, Mark K.; Spek, Rick A. A. van der; Rheenen, Wouter van; Morel, Sandrine; Bourcier, Romain; Hostettler, Isabel C.; Alg, Varinder S.; Eijk, Kristel R. van; Koido, Masaru; Akiyama, Masato; Terao, Chikashi; Matsuda, Koichi; Walters, Robin G.; Lin, Kuang; Li, Liming; Millwood, Iona Y.; Chen, Zhengming; Rouleau, Guy A.; Zhou, Sirui; Rannikmae, Kristiina; Sudlow, Cathie L. M.; Houlden, Henry; Berg, Leonard H. van den; Dina, Christian; Naggara, Olivier; Gentric, Jean-Christophe; Shotar, Eimad; Eugene, Francois; Desal, Hubert; Winsvold, Bendik S.; Borte, Sigrid; Johnsen, Marianne Bakke; Brumpton, Ben M.; Sandvei, Marie Softeland; Willer, Cristen J.; Hveem, Kristian; Zwart, John-Anker; Verschuren, W. M. Monique; Friedrich, Christoph M.; Hirsch, Sven; Schilling, Sabine; Dauvillier, Jerome; Martin, Olivier; Winsvold, Bendik S.; Winsvold, Bendik S.; Borte, Sigrid; Johnsen, Marianne Bakke; Brumpton, Ben M.; Sandvei, Marie Softeland; Willer, Cristen J.; Hveem, Kristian; Zwart, John-Anker; Bian, Zheng; Chen, Junshi; Chen, Yiping; Chen, Zhengming; Clarke, Robert; Collins, Rory; Guo, Yu; Han, Xiao; Hill, Michael; Li, Liming; Lin, Kuang; Liu, Depei; Lv, Jun; Millwood, Iona; Peto, Richard; Sansome, Sam; Walters, Robin; Yang, Xiaoming; Yu, Canqing; Koido, Masaru; Koido, Masaru; Akiyama, Masato; Terao, Chikashi; Matsuda, Koichi; Kamatani, Yoichiro; Desal, Hubert; Desal, Hubert; Bourcier, Romain; Redon, Richard; Dina, Christian; Naggara, Olivier; Eugene, Francois; Gentric, Jean-Christophe; Shotar, Eimad; Sargurupremraj, Muralidharan; Tatlisumak, Turgut; Debette, Stephanie; Werring, David J.; Houlden, Henry; Alg, Varinder S.; Hostettler, Isabel C.; Bonner, Stephen; Walsh, Daniel; Bulters, Diederik; Kitchen, Neil; Brown, Martin; Grieve, Joan; Bakker, Mark K.; Bourcier, Romain; Walters, Robin G.; Malik, Rainer; Dichgans, Martin; Sargurupremraj, Muralidharan; Tatlisumak, Turgut; Debette, Stephanie; Rinkel, Gabriel J. E.; Worrall, Bradford B.; Pera, Joanna; Slowik, Agnieszka; Broderick, Joseph P.; Werring, David J.; Woo, Daniel; Bijlenga, Philippe; Kamatani, Yoichiro; Ruigrok, Ynte M.; Jones, Gregory T.; Bown, Matthew J.; Ko, Nerissa U.; Kim, Helen; Coleman, Jonathan R. I.; Breen, Gerome; Zaroff, Jonathan G.; Klijn, Catharina J. M.; Malik, Rainer; Dichgans, Martin; Sargurupremraj, Muralidharan; Tatlisumak, Turgut; Amouyel, Philippe; Debette, Stephanie; Rinkel, Gabriel J. E.; Worrall, Bradford B.; Pera, Joanna; Slowik, Agnieszka; Gaal-Paavola, Emilia I.; Niemela, Mika; Jaaskelainen, Juha E.; Fraunberg, Mikael von und zu; Lindgren, Antti; Broderick, Joseph P.; Werring, David J.; Woo, Daniel; Redon, Richard; Bijlenga, Philippe; Kamatani, Yoichiro; Veldink, Jan H. und Ruigrok, Ynte M.
(2020):
Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors.
In: Nature Genetics, Bd. 52, Nr. 12: S. 1303-1313
Traylor, Matthew; Al Olama, Ali Amin; Lyytikainen, Leo-Pekka; Marini, Sandro; Chung, Jaeyoon; Malik, Rainer; Dichgans, Martin; Kahonen, Mika; Lehtimaki, Terho; Anderson, Christopher D.; Raitakari, Olli T. und Markus, Hugh S.
(2020):
Influence of Genetic Variation in PDE3A on Endothelial Function and Stroke.
In: Hypertension, Bd. 75, Nr. 2: S. 365-371
Georgakis, Marios K.; Gill, Dipender; Malik, Rainer; Protogerou, Athanase D.; Webb, Alastair J. S. und Dichgans, Martin
(2020):
Genetically Predicted Blood Pressure Across the Lifespan Differential Effects of Mean and Pulse Pressure on Stroke Risk.
In: Hypertension, Bd. 76, Nr. 3: S. 953-961
Gill, Dipender; Georgakis, Marios K.; Zuber, Verena; Karhunen, Ville; Burgess, Stephen; Malik, Rainer und Dichgans, Martin
(2020):
Genetically Predicted Midlife Blood Pressure and Coronary Artery Disease Risk: Mendelian Randomization Analysis.
In: Journal of the American Heart Association, Bd. 9, Nr. 14, e016773
[PDF, 1MB]
Armstrong, Nicola J.; Mather, Karen A.; Sargurupremraj, Muralidharan; Knol, Maria J.; Malik, Rainer; Satizabal, Claudia L.; Yanek, Lisa R.; Wen, Wei; Gudnason, Vilmundur G.; Dueker, Nicole D.; Elliott, Lloyd T.; Hofer, Edith; Bis, Joshua; Jahanshad, Neda; Li, Shuo; Logue, Mark A.; Luciano, Michelle; Scholz, Markus; Smith, Albert V.; Trompet, Stella; Vojinovic, Dina; Xia, Rui; Alfaro-Almagro, Fidel; Ames, David; Amin, Najaf; Amouyel, Philippe; Beiser, Alexa S.; Brodaty, Henry; Deary, Ian J.; Fennema-Notestine, Christine; Gampawar, Piyush G.; Gottesman, Rebecca; Griffanti, Ludovica; Jack, Clifford R.; Jenkinson, Mark; Jiang, Jiyang; Kral, Brian G.; Kwok, John B.; Lampe, Leonie; Liewald, David C. M.; Maillard, Pauline; Marchini, Jonathan; Bastin, Mark E.; Mazoyer, Bernard; Pirpamer, Lukas; Rafael Romero, Jose; Roshchupkin, Gennady V.; Schofield, Peter R.; Schroeter, Matthias L.; Stott, David J.; Thalamuthu, Anbupalam; Trollor, Julian; Tzourio, Christophe; Grond, Jeroen van der; Vernooij, Meike W.; Witte, Veronica A.; Wright, Margaret J.; Yang, Qiong; Morris, Zoe; Siggurdsson, Siggi; Psaty, Bruce; Villringer, Arno; Schmidt, Helena; Haberg, Asta K.; Duijn, Cornelia M. van; Jukema, J. Wouter; Dichgans, Martin; Sacco, Ralph L.; Wright, Clinton B.; Kremen, William S.; Becker, Lewis C.; Thompson, Paul M.; Mosley, Thomas H.; Wardlaw, Joanna M.; Ikram, M. Arfan; Adams, Hieab H. H.; Seshadri, Sudha; Sachdev, Perminder S.; Smith, Stephen M.; Launer, Lenore; Longstreth, William; DeCarli, Charles; Schmidt, Reinhold; Fornage, Myriam; Debette, Stephanie und Nyquist, Paul A.
(2020):
Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities.
In: Stroke, Bd. 51, Nr. 7: S. 2111-2121
Keene, Keith L.; Hyacinth, Hyacinth I.; Bis, Joshua C.; Kittner, Steven J.; Mitchell, Braxton D.; Cheng, Yu-Ching; Pare, Guillaume; Chong, Michael; O'Donnell, Martin; Meschia, James F.; Chen, Wei-Min; Sale, Michele M.; Rich, Stephen S.; Nalls, Mike A.; Zonderman, Alan B.; Evans, Michele K.; Wilson, James G.; Correa, Adolfo; Markus, Hugh S.; Traylor, Matthew; Lewis, Cathryn M.; Carty, Cara L.; Reiner, Alexander; Haessler, Jeff; Langefeld, Carl D.; Gottesman, Rebecca; Mosley, Thomas H.; Woo, Daniel; Yaffe, Kristine; Liu, YongMei; Longstreth, William T.; Psaty, Bruce M.; Kooperberg, Charles; Lange, Leslie A.; Sacco, Ralph; Rundek, Tatjana; Lee, Jin-Moo; Cruchaga, Carlos; Furie, Karen L.; Arnett, Donna K.; Benavente, Oscar R.; Grewal, Raji P.; Peddareddygari, Leema Reddy; Dichgans, Martin; Malik, Rainer; Worrall, Bradford B. und Fornage, Myriam
(2020):
Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke.
In: Stroke, Bd. 51, Nr. 8: S. 2454-2463
Marini, Sandro; Georgakis, Marios K.; Chung, Jaeyoon; Henry, Jonathan Q. A.; Dichgans, Martin; Rosand, Jonathan; Malik, Rainer und Anderson, Christopher D.
(2020):
Genetic overlap and causal inferences between kidney function and cerebrovascular disease.
In: Neurology, Bd. 94, Nr. 24, E2581-E2591
Georgakis, Marios K.; Gill, Dipender; Webb, Alastair J. S.; Evangelou, Evangelos; Elliott, Paul; Sudlow, Cathie L. M.; Dehghan, Abbas; Malik, Rainer; Tzoulaki, Ioanna und Dichgans, Martin
(2020):
Genetically determined blood pressure, antihypertensive drug classes, and risk of stroke subtypes.
In: Neurology, Bd. 95, Nr. 4, E353-E361
Rutten, Julie W.; Hack, Remco J.; Duering, Marco; Gravesteijn, Gido; Dauwerse, Johannes G.; Overzier, Maurice; Akker, Erik B. van den; Slagboom, Eline; Holstege, Henne; Nho, Kwangsik; Saykin, Andrew; Dichgans, Martin; Malik, Rainer und Oberstein, Saskia A. J. Lesnik
(2020):
Broad phenotype of cysteine-alteringNOTCH3variants in UK Biobank CADASIL to nonpenetrance.
In: Neurology, Bd. 95, Nr. 13, E1835-E1843
Sadler, Rebecca; Cramer, Julia V.; Heindl, Steffanie; Kostidis, Sarantos; Betz, Dene; Zuurbier, Kielen R.; Northoff, Bernd H.; Heijink, Marieke; Goldberg, Mark P.; Plautz, Erik J.; Roth, Stefan; Malik, Rainer; Dichgans, Martin; Holdt, Lesca M.; Benakis, Corinne; Giera, Martin; Stowe, Ann M. und Liesz, Arthur
(2020):
Short-Chain Fatty Acids Improve Poststroke Recovery via Immunological Mechanisms.
In: Journal of Neuroscience, Bd. 40, Nr. 5: S. 1162-1173
Abraham, G.; Malik, Rainer; Yonova-Doing, E.; Salim, Agus; Wang, T.; Danesh, John; Butterworth, Adam S.; Howson, Joanna M. M.; Inouye, M. und Dichgans, Martin
(20. Dezember 2019):
Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke.
In: Nature Communications, 5819
[PDF, 1MB]
Georgakis, Marios K.; Malik, Rainer und Dichgans, Martin
(27. September 2019):
Circulating Monocyte Chemoattractant Protein-1 and Risk of Stroke. Meta-Analysis of Population-Based Studies Involving 17 180 Individuals.
In: Circulation Research, Bd. 125, Nr. 8
[PDF, 500kB]
Catak, Cihan; Zedde, Marialuisa; Malik, Rainer; Janowitz, Daniel; Soric, Vivian; Seegerer, Anna; Krebs, Alexander; During, Marco; Opherk, Christian; Linn, Jennifer und Wollenweber, Frank A.
(26. April 2019):
Decreased CSF Levels of beta-Amyloid in Patients With Cortical Superficial Siderosis.
In: Frontiers in Neurology, Bd. 10, 439: S. 1-7
[PDF, 882kB]
Wollenweber, Frank A.; Opherk, Christian; Zedde, Marialuisa; Catak, Cihan; Malik, Rainer; Duering, Marco; Konieczny, Marek J.; Pascarella, R.; Samões, R.; Correia, M.; Martí-Fàbregas, J.; Linn, Jennifer und Dichgans, Martin
(19. Februar 2019):
Prognostic relevance of cortical superficial siderosis in cerebral amyloid angiopathy.
In: Neurology, Bd. 92, Nr. 8, e792-e801
[PDF, 536kB]
Chauhan, Ganesh; Malik, Rainer und Dichgans, Martin
(16. Januar 2019):
Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.
In: Neurology, Bd. 92, Nr. 5, e486-e503
[PDF, 372kB]
Georgakis, Marios K.; Gill, Dipender; Rannikmae, Kristiina; Traylor, Matthew; Anderson, Christopher D.; Lee, Jin-Moo; Kamatani, Yoichiro; Hopewell, Jemma C.; Worrall, Bradford B.; Bernhagen, Jürgen; Sudlow, Cathie L. M.; Malik, Rainer und Dichgans, Martin
(Januar 2019):
Genetically Determined Levels of Circulating Cytokines and Risk of Stroke. Role of Monocyte Chemoattractant Protein-1.
In: Circulation, Bd. 139, Nr. 2
[PDF, 772kB]
Chung, Jaeyoon; Marini, Sandro; Pera, Joanna; Norrving, Bo; Jimenez-Conde, Jordi; Roquer, Jaume; Fernandez-Cadenas, Israel; Tirschwell, David L.; Selim, Magdy; Brown, Devin L.; Silliman, Scott L.; Worrall, Bradford B.; Meschia, James F.; Demel, Stacie; Greenberg, Steven M.; Slowik, Agnieszka; Lindgren, Arne; Schmidt, Reinhold; Traylor, Matthew; Sargurupremraj, Muralidharan; Tiedt, Steffen; Malik, Rainer; Debette, Stephanie; Dichgans, Martin; Langefeld, Carl D.; Woo, Daniel; Rosand, Jonathan und Anderson, Christopher D.
(2019):
Genome-wide association study of cerebral small vessel disease reveals established and novel loci.
In: Brain, Bd. 142: S. 3176-3189
Prestel, Matthias; Prell-Schicker, Caroline; Webb, Tom; Malik, Rainer; Lindner, Barbara; Ziesch, Natalie; Rex-Haffner, Monika; Roeh, Simone; Viturawong, Thanatip; Lehm, Manuel; Mokry, Michal; den Ruijter, Hester; Haitjema, Saskia; Asare, Yaw; Soellner, Flavia; Najafabadi, Maryam Ghaderi; Aherrahrou, Redouane; Civelek, Mete; Samani, Nilesh J.; Mann, Matthias; Haffner, Christof und Dichgans, Martin
(2019):
The Atherosclerosis Risk Variant rs2107595 Mediates Allele-Specific Transcriptional Regulation of HDAC9 via E2F3 and Rb1.
In: Stroke, Bd. 50, Nr. 10: S. 2651-2660
Traylor, Matthew; Anderson, Christopher D.; Rutten-Jacobs, Loes C. A.; Falcone, Guido J.; Comeau, Mary E.; Ay, Hakan; Sudlow, Cathie L. M.; Xu, Huichun; Mitchell, Braxton D.; Cole, John W.; Rexrode, Kathryn; Jimenez-Conde, Jordi; Schmidt, Reinhold; Grewal, Raji P.; Sacco, Ralph; Ribases, Marta; Rundek, Tatjana; Rosand, Jonathan; Dichgans, Martin; Lee, Jin-Moo; Langefeld, Carl D.; Kittner, Steven J.; Markus, Hugh S.; Woo, Daniel und Malik, Rainer
(2019):
Subtype Specificity of Genetic Loci Associated With Stroke in 16 664 Cases and 32 792 Controls.
In: Circulation-Genomic and Precision Medicine, Bd. 12, Nr. 7, e002338
Carter, Alice R.; Gill, Dipender; Davies, Neil M.; Taylor, Amy E.; Tillmann, Taavi; Vaucher, Julien; Wootton, Robyn E.; Munafo, Marcus R.; Hemani, Gibran; Malik, Rainer; Seshadri, Sudha; Woo, Daniel; Burgess, Stephen; Smith, George Davey; Holmes, Michael V.; Tzoulaki, Ioanna; Howe, Laura D. und Dehghan, Abbas
(2019):
Understanding the consequences of education inequality on cardiovascular disease: mendelian randomisation study.
In: BMJ-British Medical Journal, Bd. 365, l1855
[PDF, 605kB]
Valdes-Marquez, Elsa; Parish, Sarah; Clarke, Robert; Stari, Traiani; Worrall, Bradford B.; Hopewell, Jemma C.; Slowik, Agnieszka; Hofman, Albert; Algra, Ale; Reiner, Alex P.; Doney, Alexander S. F.; Gschwendtner, Andreas; Ilinca, Andreea; Giese, Anne-Katrin; Lindgren, Arne; Vicente, Astrid M.; Norrving, Bo; Nordestgaard, Borge G.; Mitchell, Braxton D.; Psaty, Bruce M.; Carty, Cara L.; Sudlow, Cathie L. M.; Anderson, Christopher; Levi, Christopher R.; Satizabal, Claudia L.; Palmer, Colin N. A.; Gamble, Dale M.; Woo, Daniel; Saleheen, Danish; Ringelstein, E. Bernd; Valdimarsson, Einar M.; Holliday, Elizabeth G.; Davies, Gail; Chauhan, Ganesh; Pasterkamp, Gerard; Boncoraglio, Giorgio B.; Kuhlenbaeumer, Gregor; Thorleifsson, Gudmar; Falcone, Guido J.; Pare, Guillaume; Schmidt, Helena; Delavaran, Hossein; Markus, Hugh S.; Aparicio, Hugo J.; Deary, Ian; Cotlarciuc, Ioana; Fernandez-Cadenas, Israel; Meschia, James F.; Liu, Jingmin; Montaner, Joan; Pera, Joanna; Cole, John; Attia, John R.; Rosand, Jonathan; Ferro, Jose M.; Bis, Joshua C.; Furie, Karen; Stefansson, Kari; Berger, Klaus; Kostulas, Konstantinos; Rannikmae, Kristiina; Ikram, M. Arfan; Benn, Marianne; Dichgans, Martin; Pandolfo, Massimo; Traylor, Matthew; Walters, Matthew; Sale, Michele; Nalls, Michael A.; Fornage, Myriam; van Zuydam, Natalie R.; Sharma, Pankaj; Abrantes, Patricia; de Bakker, Paul I. W.; Higgins, Peter; Lichtner, Peter; Rothwell, Peter M.; Amouyel, Philippe; Yang, Qiong; Malik, Rainer; Schmidt, Reinhold; Lemmens, Robin; van der Laan, Sander W.; Pulit, Sara L.; Abboud, Sherine; Oliveira, Sofia A.; Gretarsdottir, Solveig; Debette, Stephanie; Williams, Stephen R.; Bevan, Steve; Kittner, Steven J.; Seshadri, Sudha; Mosley, Thomas; Battey, Thomas W. K.; Tatlisumak, Turgut; Thorsteinsdottir, Unnur; Thijs, Vincent N. S.; Longstreth, W. T.; Zhao, Wei; Chen, Wei-Min und Cheng, Yu-Ching
(2019):
Relative effects of LDL-C on ischemic stroke and coronary disease A Mendelian randomization study.
In: Neurology, Bd. 92, Nr. 11, E1176-E1187
Kogelman, Lisette J. A.; Esserlind, Ann-Louise; Christensen, Anne Francke; Awasthi, Swapnil; Ripke, Stephan; Ingason, Andres; Davidsson, Olafur B.; Erikstrup, Christian; Hjalgrim, Henrik; Ullum, Henrik; Olesen, Jes; Hansen, Thomas Folkmann; Gudbjartsson, Daniel; Gastafsson, Omar; Stefansson, Kari; Stefansson, Hreinn; Porsteinsdottir, Unnur; Andersen, Steffen; Banasik, Karina; Brunak, Soren; Buil, Alfonso; Burgdorf, Kristoffer; Gregor, Jemec; Jennum, Poul; Nielsen, Kasper Rene; Nyegaard, Mette; Paarup, Helene Mariana; Pedersen, Ole Birger; Sorensen, Erik; Werge, Thomas; Anttila, Verneri; Artto, Ville; Belin, Andrea Carmine; de Boer, Irene; Boomsma, Dorret; Borte, Sigrid; Chasman, Daniel; Cherkas, Lynn; Cormand, Bru; Cuenca-Leon, Ester; Davey-Smith, George; Dichgans, Martin; van Duijn, Cornelia; Esko, Tonu; Ferrari, Michel; Frants, Rune R.; Freilinger, Tobias; Furlotte, Nick; Gormley, Padhraig; Griffiths, Lyn; Hamalainen, Eija; Hiekkala, Marjo; Ikram, M. Arfan; Jarvelin, Marjo-Riitta; Kajanne, Risto; Kallela, Mikko; Kaprio, Jaakko; Kaunisto, Mari; Kubisch, Christian; Kurki, Mitja; Kurth, Tobias; Launer, Lenore; Lehtimaki, Terho; Lessel, Davor; Ligthart, Lannie; Litterman, Nadia; van den Maagdenberg, Arn; Macaya, Alfons; Malik, Rainer; Mangino, Massimo; McMahon, George; Muller-Myhsok, Bertram; Neale, Benjamin M.; Northover, Carrie; Nyholt, Dale R.; Palotie, Aarno; Palta, Priit; Pedersen, Linda; Pedersen, Nancy; Posthuma, Danielle; Pozo-Rosich, Patricia; Pressman, Alice; Raitakari, Olli; Schurks, Markus; Sintas, Celia; Steinberg, Stacy; Strachan, David; Terwindt, Gisela; Vila-Pueyo, Marta; Wessman, Maija; Winsvold, Bendik S.; Zhao, Huiying und Zwart, John-Anker
(2019):
Migraine polygenic risk score associates with efficacy of migraine-specific drugs.
In: Neurology-Genetics, Bd. 5, Nr. 6, e364
Gill, Dipender; Georgakis, Marios K.; Koskeridis, Fotios; Jiang, Lan; Feng, Qiping; Wei, Wei-Qi; Theodoratou, Evropi; Elliott, Paul; Denny, Joshua C.; Malik, Rainer; Evangelou, Evangelos; Dehghan, Abbas; Dichgans, Martin und Tzoulaki, Ioanna
(2019):
Use of Genetic Variants Related to Antihypertensive Drugs to Inform on Efficacy and Side Effects.
In: Circulation, Bd. 140, Nr. 4: S. 270-279
Marini, Sandro; Crawford, Katherine; Morotti, Andrea; Lee, Myung J.; Pezzini, Alessandro; Moomaw, Charles J.; Flaherty, Matthew L.; Montaner, Joan; Roquer, Jaume; Jimenez-Conde, Jordi; Giralt-Steinhauer, Eva; Elosua, Roberto; Cuadrado-Godia, Elisa; Soriano-Tarraga, Carolina; Slowik, Agnieszka; Jagiella, Jeremiasz M.; Pera, Joanna; Urbanik, Andrzej; Pichler, Alexander; Hansen, Bjorn M.; McCauley, Jacob L.; Tirschwell, David L.; Selim, Magdy; Brown, Devin L.; Silliman, Scott L.; Worrall, Bradford B.; Meschia, James F.; Kidwell, Chelsea S.; Testai, Fernando D.; Kittner, Steven J.; Schmidt, Helena; Enzinger, Christian; Deary, Lan J.; Rannikmae, Kristiina; Samarasekera, Neshika; Salman, Rustam Al-Shahi; Sudlow, Catherine L.; Klijn, Catharina J. M.; van Nieuwenhuizen, Koen M.; Fernandez-Cadenas, Israel; Delgado, Pilar; Nonving, Bo; Lindgren, Ame; Goldstein, Joshua N.; Viswanathan, Anand; Greenberg, Steven M.; Falcone, Guido J.; Biffi, Alessandro; Langefeld, Carl D.; Woo, Daniel; Rosand, Jonathan; Anderson, Christopher D.; Smoller, Sylvia; Sorkin, John; Wang, Xingwu; Selim, Magdy; Pikula, Aleksandra; Wolf, Philip; Debette, Stephanie; Seshadri, Sudha; de Bakker, Paul; Chasman, Daniel; Rexrode, Kathryn; Chen, Ida; Rotter, Jerome; Luke, May; Sale, Michelle; Lee, Tsong-Hai; Chang, Ku-Chou; Elkind, Mitchell; Goldstein, Larry; James, Michael (Luke); Breteler, Monique; O'Donnell, Chris; Leys, Didier; Carty, Cara; Kidwell, Chelsea; Olesen, Jes; Sharma, Pankaj; Rich, Stephen; Tatlisumak, Turgot; Happola, Olli; Bijlenga, Philippe; Soriano, Carolina; Giralt, Eva; Roquer, Jaume; Jimenez-Conde, Jordi; Cotlarcius, Loana; Hardy, John; Korostynski, Michal; Boncoraglio, Giorgio; Ballabio, Elena; Parati, Eugenio; Mateusz, Adamski; Urbanik, Andrzej; Dziedzic, Tomasz; Jagiella, Jeremiasz; Gasowski, Jerzy; Wnuk, Marcin; Olszanecki, Rafaf; Pera, Joanna; Slowik, Agnieszka; Juchniewicz, Karol Jozef; Levi, Christopher; Nyquist, Paul; Cendes, Iscia; Cabral, Norberto; Franca, Paulo; Goncalves, Anderson; Keller, Lina; Crisby, Milita; Kostulas, Konstantinos; Lennnnens, Robin; Ahmadi, Kourosh; Opherk, Christian; Duering, Marco; Dichgans, Martin; Malik, Rainer; Gonik, Mariya; Staals, Julie; Melander, Olle; Burri, Philippe; Sadr-Nabavi, Ariane; Romero, Javier; Biffi, Alessandro; Anderson, Chris; Falcone, Guido; Brouwers, Bart; Rosand, Jonathan; Rost, Natalia; Du, Rose; Kourkoulis, Christina; Battey, Thomas; Lubitz, Steven; Müller-Myhsok, Bertram; Meschia, James; Brott, Thomas; Pare, Guillaume; Pichler, Alexander; Enzinger, Christian; Schmidt, Helena; Schmidt, Reinhold; Seiler, Stephan; Blanton, Susan; Yamada, Yoshiji; Bersano, Anna; Rundek, Tatiana; Sacco, Ralph; Chan, Yu-Feng Yvonne; Gschwendtner, Andreas; Deng, Zhen; Barr, Taura; Gwinn, Katrina; Corriveau, Roderick; Singleton, Andrew; Waddy, Salina; Launer, Lenore; Chen, Christopher; Le, Kim En; Lee, Wei Ling; Tan, Eng King; Olugbodi, Akintomi; Rothwell, Peter; Schilling, Sabrina; Mok, Vincent; Lebedeva, Elena; Jem, Christina; Jood, Katarina; Olsson, Sandra; Kim, Helen; Lee, Chaeyoung; Kilarski, Laura; Markus, Hugh; Peycke, Jennifer; Bevan, Steve; Sheu, Wayne; Chiou, Hung Yi; Chern, Joseph; Giraldo, Elias; Taqi, Muhammad; Jain, Vivek; Lam, Olivia; Howard, George; Woo, Daniel; Kittner, Steven; Mitchell, Braxton; Cole, John; O'Connell, Jeff; Milewicz, Dianna; Illoh, Kachikwu; Worrall, Bradford; Stine, Colin; Karaszewski, Bartosz; Werring, David; Sofat, Reecha; Smalley, June; Lindgren, Arne; Hansen, Bjorn; Norrving, Bo; Smith, Gustav; Martin, Juan Jose; Thijs, Vincent; Klijn, Karin; van't Hof, Femke; Algra, Ale; Macleod, Mary; Perry, Rodney; Arnett, Donna; Pezzini, Alessandro; Padovani, Alessandro; Cramer, Steve; Fisher, Marl; Saleheen, Danish; Broderick, Joseph; Kissela, Brett; Doney, Alex; Sudlow, Cathie; Rannikmae, Kristiina; Silliman, Scott; McDonough, Caitrin; Walters, Matthew; Pedersen, Annie; Nakagawa, Kazuma; Chang, Christy; Dobbins, Mark; McArdle, Patrick; Chang, Yu-Ching; Brown, Robert; Brown, Devin; Holliday, Elizabeth; Kalaria, Raj; Maguire, Jane; Hunter, John; Attia, John; Farrall, Martin; Giese, Anne-Katrin; Fomage, Myriam; Majersik, Jennifer; Cushman, Maly; Keene, Keith; Bennett, Siiri; Tirschwell, David; Psaty, Bruce; Reiner, Alex; Longstreth, Will; Spence, David; Montaner, Joan; Fernandez-Cadenas, Israel; Langefeld, Carl; Bushnell, Cheryl; Heitsch, Laura; Lee, Jin-Moo und Sheth, Kevin
(2019):
Association of Apolipoprotein E With Intracerebral Hemorrhage Risk by Race/Ethnicity A Meta-analysis.
In: Jama Neurology, Bd. 76, Nr. 4: S. 480-491
Cole, John W.; Xu, Huichun; Ryan, Kathleen; Jaworek, Thomas; Dueker, Nicole; McArdle, Patrick; Gaynor, Brady; Cheng, Yu-Ching; O'Connell, Jeffrey; Bevan, Steve; Malik, Rainer; Ahmed, Naveed Uddin; Amouyel, Philippe; Anjum, Sheraz; Bis, Joshua C.; Crosslin, David; Danesh, John; Engelter, Stefan T.; Fornage, Myriam; Frossard, Philippe; Gieger, Christian; Giese, Anne-Katrin; Grond-Ginsbach, Caspar; Ho, Weang Kee; Holliday, Elizabeth; Hopewell, Jemma; Hussain, M.; Iqbal, W.; Jabeen, S.; Jannes, Jim; Kamal, Ayeesha; Kamatani, Yoichiro; Kanse, Sandip; Kloss, Manja; Lathrop, Mark; Leys, Didier; Lindgren, Arne; Longstreth, W. T.; Mahmood, Khalid; Meisinger, Christa; Metso, Tiina M.; Mosley, Thomas; Müller-Nurasyid, Martina; Norrving, Bo; Parati, Eugenio; Peters, Annette; Pezzini, Alessandro; Quereshi, I.; Rasheed, Asif; Rauf, A.; Salam, T.; Shen, Jess; Slowik, Agnieszka; Stanne, Tara; Strauch, Konstantin; Tatlisumak, Turgut; Thijs, Vincent N.; Tiedt, Steffen; Traylor, Matthew; Waldenberger, Melanie; Walters, Matthew; Zhao, Wei; Boncoraglio, Giorgio; Debette, Stephanie; Jern, Christina; Levi, Christopher; Markus, Hugh; Meschia, James; Rolfs, Arndt; Rothwell, Peter; Saleheen, Danish; Seshadri, Sudha; Sharma, Pankaj; Sudlow, Cathie; Worrall, Bradford; Stine, O. Colin; Kittner, Steven J. und Mitchell, Braxton D.
(2018):
Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke.
In: PloS one 13(11), e0206554 [PDF, 779kB]
In: PloS one 13(11), e0206554 [PDF, 779kB]
Malik, Rainer und Dichgans, Martin
(2018):
Challenges and opportunities in stroke genetics.
In: Cardiovascular Research, Bd. 114, Nr. 9: S. 1226-1240
Duering, Marco; Finsterwalder, Sofia; Baykara, Ebru; Tuladhar, Anil Man; Gesierich, Benno; Konieczny, Marek J.; Malik, Rainer; Franzmeier, Nicolai; Ewers, Michael; Jouvent, Eric; Biessels, Geert Jan; Schmidt, Reinhold; Leeuw, Frank-Erik de; Pasternak, Ofer und Dichgans, Martin
(2018):
Free water determines diffusion alterations and clinical status in cerebral small vessel disease.
In: Alzheimers & Dementia, Bd. 14, Nr. 6: S. 764-774
Malik, Rainer; Rannikmaee, Kristiina; Traylor, Matthew; Georgakis, Marios K.; Sargurupremraj, Muralidharan; Markus, Hugh S.; Hopewell, Jemma C.; Debette, Stephanie; Sudlow, Cathie L. M. und Dichgans, Martin
(2018):
Genome-wide meta-analysis identifies 3 novel loci associated with stroke.
In: Annals of Neurology, Bd. 84, Nr. 6: S. 934-939
Malik, Rainer; Chauhan, Ganesh; Traylor, Matthew; Sargurupremraj, Muralidharan; Okada, Yukinori; Mishra, Aniket; Rutten-Jacobs, Loes; Giese, Anne-Katrin; Laan, Sander W. van der; Gretarsdottir, Solveig; Anderson, Christopher D.; Chong, Michael; Adams, Hieab H. H.; Ago, Tetsuro; Almgren, Peter; Amouyel, Philippe; Ay, Hakan; Bartz, Traci M.; Benavente, Oscar R.; Bevan, Steve; Boncoraglio, Giorgio B.; Brown, Robert D. Jr.; Butterworth, Adam S.; Carrera, Caty; Carty, Cara L.; Chasman, Daniel I.; Chen, Wei-Min; Cole, John W.; Correa, Adolfo; Cotlarciuc, Ioana; Cruchaga, Carlos; Danesh, John; Bakker, Paul I. W. de; DeStefano, Anita L.; Hoed, Marcel den; Duan, Qing; Engelter, Stefan T.; Falcone, Guido J.; Gottesman, Rebecca F.; Grewal, Raji P.; Gudnason, Vilmundur; Gustafsson, Stefan; Haessler, Jeffrey; Harris, Tamara B.; Hassan, Ahamad; Havulinna, Aki S.; Heckbert, Susan R.; Holliday, Elizabeth G.; Howard, George; Hsu, Fang-Chi; Hyacinth, Hyacinth I.; Ikram, M. Arfan; Ingelsson, Erik; Irvin, Marguerite R.; Jian, Xueqiu; Jimenez-Conde, Jordi; Johnson, Julie A.; Jukema, J. Wouter; Kanai, Masahiro; Keene, Keith L.; Kissela, Brett M.; Kleindorfer, Dawn O.; Kooperberg, Charles; Kubo, Michiaki; Lange, Leslie A.; Langefeld, Carl D.; Langenberg, Claudia; Launer, Lenore J.; Lee, Jin-Moo; Lemmens, Robin; Leys, Didier; Lewis, Cathryn M.; Lin, Wei-Yu; Lindgren, Arne G.; Lorentzen, Erik; Magnusson, Patrik K.; Maguire, Jane; Manichaikul, Ani; McArdle, Patrick F.; Meschia, James F.; Mitchell, Braxton D.; Mosley, Thomas H.; Nalls, Michael A.; Ninomiya, Toshiharu; O'Donnell, Martin J.; Psaty, Bruce M.; Pulit, Sara L.; Rannikmae, Kristiina; Reiner, Alexander P.; Rexrode, Kathryn M.; Rice, Kenneth; Rich, Stephen S.; Ridker, Paul M.; Rost, Natalia S.; Rothwell, Peter M.; Rotter, Jerome I.; Rundek, Tatjana; Sacco, Ralph L.; Sakaue, Saori; Sale, Michele M.; Salomaa, Veikko; Sapkota, Bishwa R.; Schmidt, Reinhold; Schmidt, Carsten O.; Schminke, Ulf; Sharma, Pankaj; Slowik, Agnieszka; Sudlow, Cathie L. M.; Tanislav, Christian; Tatlisumak, Turgut; Taylor, Kent D.; Thijs, Vincent N. S.; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Tiedt, Steffen; Trompet, Stella; Tzourio, Christophe; van Duijn, Cornelia M.; Walters, Matthew; Wareham, Nicholas J.; Wassertheil-Smoller, Sylvia; Wilson, James G.; Wiggins, Kerri L.; Yang, Qiong; Yusuf, Salim; Bis, Joshua C.; Pastinen, Tomi; Ruusalepp, Arno; Schadt, Eric E.; Koplev, Simon; Bjorkegren, Johan L. M.; Codoni, Veronica; Civelek, Mete; Smith, Nicholas L.; Trégouët, David-Alexandre ORCID: https://orcid.org/0000-0001-9084-7800; Christophersen, Ingrid E.; Roselli, Carolina; Lubitz, Steven A.; Ellinor, Patrick T.; Tai, E. Shyong; Kooner, Jaspal S.; Kato, Norihiro; He, Jiang; Harst, Pim van der; Elliott, Paul; Chambers, John C.; Takeuchi, Fumihiko; Johnson, Andrew D.; Sanghera, Dharambir K.; Melander, Olle; Jern, Christina; Strbian, Daniel; Fernandez-Cadenas, Israel; Longstreth, W. T. Jr.; Rolfs, Arndt; Hata, Jun; Woo, Daniel; Rosand, Jonathan; Pare, Guillaume; Hopewell, Jemma C.; Saleheen, Danish; Stefansson, Kari; Worrall, Bradford B.; Kittner, Steven J.; Seshadri, Sudha; Fornage, Myriam; Markus, Hugh S.; Howson, Joanna M. M.; Kamatani, Yoichiro; Debette, Stephanie und Dichgans, Martin
(2018):
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
In: Nature Genetics, Bd. 50, Nr. 4: S. 524-537
ORCID: https://orcid.org/0000-0001-9084-7800; Christophersen, Ingrid E.; Roselli, Carolina; Lubitz, Steven A.; Ellinor, Patrick T.; Tai, E. Shyong; Kooner, Jaspal S.; Kato, Norihiro; He, Jiang; Harst, Pim van der; Elliott, Paul; Chambers, John C.; Takeuchi, Fumihiko; Johnson, Andrew D.; Sanghera, Dharambir K.; Melander, Olle; Jern, Christina; Strbian, Daniel; Fernandez-Cadenas, Israel; Longstreth, W. T. Jr.; Rolfs, Arndt; Hata, Jun; Woo, Daniel; Rosand, Jonathan; Pare, Guillaume; Hopewell, Jemma C.; Saleheen, Danish; Stefansson, Kari; Worrall, Bradford B.; Kittner, Steven J.; Seshadri, Sudha; Fornage, Myriam; Markus, Hugh S.; Howson, Joanna M. M.; Kamatani, Yoichiro; Debette, Stephanie und Dichgans, Martin
(2018):
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
In: Nature Genetics, Bd. 50, Nr. 4: S. 524-537
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(2018):
Multi-ethnic genome-wide association study for atrial fibrillation.
In: Nature Genetics, Bd. 50, Nr. 9: S. 1225-1233
Rutten-Jacobs, Loes Ca; Larsson, Susanna C.; Malik, Rainer; Rannikmae, Kristiina; Sudlow, Cathie L.; Dichgans, Martin; Markus, Hugh S. und Traylor, Matthew
(2018):
Genetic risk, incident stroke, and the benefits of adhering to a healthy lifestyle: cohort study of 306 473 UK Biobank participants.
In: BMJ-British Medical Journal, Bd. 363, k4168
[PDF, 420kB]
Laan, Sander W. van der; Siemelink, Marten A.; Haitjema, Saskia; Asl, Hassan Foroughi; Perisic, Ljubica; Mokry, Michal; Setten, Jessica van; Malik, Rainer; Dichgans, Martin; Worrall, Bradford B.; Samani, Nilesh J.; Schunkert, Heribert; Erdmann, Jeanette; Hedin, Ulf; Paulsson-Berne, Gabrielle; Bjorkegrenn, Johan L. M.; Borst, Gert J. de; Asselbergs, Folkert W.; Ruijter, Hester M. den; Bakker, Paul I. W. de und Pasterkamp, Gerard
(2018):
Genetic Susceptibility Loci for Cardiovascular Disease and Their Impact on Atherosclerotic Plaques.
In: Circulation-Genomic and Precision Medicine, Bd. 11, Nr. 9, e002115
Rutten-Jacobs, Loes C. A.; Tozer, Daniel J.; Düring, Marco; Malik, Rainer; Dichgans, Martin; Markus, Hugh S. und Traylor, Matthew
(2018):
Genetic Study of White Matter Integrity in UK Biobank (N=8448) and the Overlap With Stroke, Depression, and Dementia.
In: Stroke, Bd. 49, Nr. 6: S. 1340-1347
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(2018):
Genetic correlations among psychiatric and immune-related phenotypes based on genome-wide association data.
In: American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, Bd. 177, Nr. 7: S. 641-657
Wierer, Michael; Prestel, Matthias; Schiller, Herbert B.; Yan, Guangyao; Schaab, Christoph; Azghandi, Sepiede; Werner, Julia; Kessler, Thorsten; Malik, Rainer; Murgia, Marta; Aherrahrou, Zouhair; Schunkert, Heribert; Dichgans, Martin und Mann, Matthias
(2018):
Compartment-resolved Proteomic Analysis of Mouse Aorta during Atherosclerotic Plaque Formation Reveals Osteoclast-specific Protein Expression.
In: Molecular & Cellular Proteomics, Bd. 17, Nr. 2: S. 321-334
Hopewell, Jemma C.; Malik, Rainer; Valdes-Marquez, Elsa; Worrall, Bradford B. und Collins, Rory
(2018):
Differential effects of PCSK9 variants on risk of coronary disease and ischaemic stroke.
In: European Heart Journal, Bd. 39, Nr. 5: S. 354-359
Crawford, Katherine M.; Gallego-Fabrega, Cristina; Kourkoulis, Christina; Miyares, Laura; Marini, Sandro; Flannick, Jason; Burtt, Noel P.; Grotthuss, Marcin von; Alexander, Benjamin; Costanzo, Maria C.; Vaishnav, Neil H.; Malik, Rainer; Hall, Jennifer L.; Chong, Michael; Rosand, Jonathan und Falcone, Guido J.
(2018):
Cerebrovascular Disease Knowledge Portal An Open-Access Data Resource to Accelerate Genomic Discoveries in Stroke.
In: Stroke, Bd. 49, Nr. 2: S. 470-475
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Gill, Dipender; Georgakis, Marios K.; Laffan, Mike; Sabater-Lleal, Maria; Malik, Rainer; Tzoulaki, Ioanna; Veltkamp, Roland und Dehghan, Abbas
(2018):
Genetically Determined FXI (Factor XI) Levels and Risk of Stroke.
In: Stroke, Bd. 49, Nr. 11: S. 2761-2763
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Karbalai, Nazanin; Czamara, Darina; Moll, Kristina; Ramus, Franck; Malik, Rainer; Scerri, Thomas S.; Schumacher, Johannes; Morris, Andrew P.; Bourgeron, Thomas; Monaco, Anthony P.; Paracchini, Silvia; Fisher, Simon E.; Nöthen, Markus M.; Schulte-Körne, Gerd und Müller-Myhsok, Bertram
(2017):
Identification of genetic interactions involved in dyslexia pathogenesis.
In: European Neuropsychopharmacology, Bd. 27, Nr. Suppl. 2:
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Malik, Rainer; Dau, Therese; Gonik, Maria; Sivakumar, Anirudh; Deredge, Daniel J.; Edeleva, Evgeniia V.; Götzfried, Jessica; Laan, Sander W. van der; Pasterkamp, Gerard; Beaufort, Nathalie; Seixas, Susana; Bevan, Steve; Lincz, Lisa F.; Holliday, Elizabeth G.; Burgess, Annette I.; Rannikmae, Kristiina; Minnerup, Jens; Kriebel, Jennifer; Waldenberger, Melanie; Müller-Nurasyid, Martina; Lichtner, Peter; Saleheen, Danish; Rothwell, Peter M.; Levi, Christopher; Attia, John; Sudlow, Cathie L. M.; Braun, Dieter; Markus, Hugh S.; Wintrode, Patrick L.; Berger, Klaus; Jenne, Dieter E. und Dichgans, Martin
(2017):
Common coding variant in SERPINA1 increases the risk for large artery stroke.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 114, Nr. 14: S. 3613-3618
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Tiedt, Steffen; Prestel, Matthias; Malik, Rainer; Schieferdecker, Nicola; Düring, Marco; Kautzky, Veronika; Stoycheva, Ivelina; Boeck, Julia; Northoff, Bernd H.; Klein, Matthias; Dorn, Franziska; Krohn, Knut; Teupser, Daniel; Liesz, Arthur; Plesnila, Nikolaus; Holdt, Lesca Miriam und Dichgans, Martin
(2017):
RNA-Seq Identifies Circulating miR-125a-5p, miR-125b-5p, and miR-143-3p as Potential Biomarkers for Acute Ischemic Stroke.
In: Circulation Research, Bd. 121, Nr. 8: S. 970-980
Llovera, Gemma; Benakis, Corinne; Enzmann, Gaby; Cai, Ruiyao; Arzberger, Thomas; Ghasemigharagoz, Alireza; Mao, Xiang; Malik, Rainer; Lazarevic, Ivana; Liebscher, Sabine; Ertürk, Ali; Meissner, Lilja; Vivien, Denis; Haffner, Christof; Plesnila, Nikolaus; Montaner, Joan; Engelhardt, Britta und Liesz, Arthur
(2017):
The choroid plexus is a key cerebral invasion route for T cells after stroke.
In: Acta Neuropathologica, Bd. 134, Nr. 6: S. 851-868
Christophersen, Ingrid E.; Rienstra, Michiel; Roselli, Carolina; Yin, Xiaoyan; Geelhöd, Bastiaan; Barnard, John; Lin, Honghuang; Arking, Dan E.; Smith, Albert V.; Albert, Christine M.; Chaffin, Mark; Tucker, Nathan R.; Li, Molong; Klarin, Derek; Bihlmeyer, Nathan A.; Low, Siew-Kee; Weeke, Peter E.; Müller-Nurasyid, Martina; Smith, J. Gustav; Brody, Jennifer A.; Niemeijer, Maartje N.; Dörr, Marcus; Trompet, Stella; Huffman, Jennifer; Gustafsson, Stefan; Schurmann, Claudia; Kleber, Marcus E.; Lyytikainen, Leo-Pekka; Seppala, Ilkka; Malik, Rainer; Horimoto, Andrea R. V. R.; Perez, Marco; Sinisalo, Juha; äschbacher, Stefanie; Theriault, Sebastien; Yao, Jie; Radmanesh, Farid; Weiss, Stefan; Teumer, Alexander; Choi, Seung Hoan; Weng, Lu-Chen; Clauss, Sebastian; Deo, Rajat; Rader, Daniel J.; Shah, Svati H.; Sun, Albert; Hopewell, Jemma C.; Debette, Stephanie; Chauhan, Ganesh; Yang, Qiong; Worrall, Bradford B.; Pare, Guillaume; Kamatani, Yoichiro; Hagemeijer, Yanick P.; Verweij, Niek; Siland, Joylene E.; Kubo, Michiaki; Smith, Jonathan D.; Wagoner, David R. van; Bis, Joshua C.; Perz, Siegfried; Psaty, Bruce M.; Ridker, Paul M.; Magnani, Jared W.; Harris, Tamara B.; Launer, Lenore J.; Shömaker, M. Benjamin; Padmanabhan, Sandosh; Hässler, Jeffrey; Bartz, Traci M.; Waldenberger, Melanie; Lichtner, Peter; Arendt, Marina; Krieger, Jose E.; Kähönen, Mika; Risch, Lorenz; Mansur, Alfredo J.; Peters, Annette; Smith, Blair H.; Lind, Lars; Scott, Stuart A.; Lu, Yingchang; Bottinger, Erwin B.; Hernesniemi, Jussi; Lindgren, Cecilia M.; Wong, Jörge A.; Huang, Jie; Eskola, Markku; Morris, Andrew P.; Ford, Ian; Reiner, Alex P.; Delgado, Graciela; Chen, Lin Y.; Chen, Yii-Der Ida; Sandhu, Roopinder K.; Li, Man; Börwinkle, Eric; Eisele, Lewin; Lannfelt, Lars; Rost, Natalia; Anderson, Christopher D.; Taylor, Kent D.; Campbell, Archie; Magnusson, Patrik K.; Porteous, David; Hocking, Lynne J.; Vlachopoulou, Efthymia; Pedersen, Nancy L.; Nikus, Kjell; Orho-Melander, Marju; Hamsten, Anders; Heeringa, Jan; Denny, Joshua C.; Kriebel, Jennifer; Darbar, Dawood; Newton-Cheh, Christopher; Shaffer, Christian; Macfarlane, Peter W.; Heilmann-Heimbach, Stefanie; Almgren, Peter; Huang, Paul L.; Sotoodehnia, Nona; Soliman, Elsayed Z.; Uitterlinden, Andre G.; Hofman, Albert; Franco, Oscar H.; Völker, Uwe; Jöckel, Karl-Heinz; Sinner, Moritz F.; Lin, Henry J.; Guo, Xiuqing; Dichgans, Martin; Ingelsson, Erik; Kooperberg, Charles; Melander, Olle; Loos, Ruth J. F.; Laurikka, Jari; Conen, David; Rosand, Jonathan; Harst, Pim van der; Lokki, Marja-Liisa; Kathiresan, Sekar; Pereira, Alexandre; Jukema, J. Wouter; Hayward, Caroline; Rotter, Jerome I.; März, Winfried; Lehtimaki, Terho; Stricker, Bruno H.; Chung, Mina K.; Felix, Stephan B.; Gudnason, Vilmundur; Alonso, Alvaro; Roden, Dan M.; Kääb, Stefan; Chasman, Daniel I.; Heckbert, Susan R.; Benjamin, Emelia J.; Tanaka, Toshihiro; Lunetta, Kathryn L.; Lubitz, Steven A. und Ellinor, Patrick T.
(2017):
Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.
In: Nature Genetics, Bd. 49, Nr. 6: S. 946-952
Traylor, Matthew; Malik, Rainer; Nalls, Mike A.; Cotlarciuc, Ioana; Radmanesh, Farid; Thorleifsson, Gudmar; Hanscombe, Ken B.; Langefeld, Carl; Saleheen, Danish; Rost, Natalia S.; Yet, Idil; Spector, Tim D.; Bell, Jordana T.; Hannon, Eilis; Mill, Jonathan; Chauhan, Ganesh; Debette, Stephanie; Bis, Joshua C.; Longstreth, W. T.; Ikram, M. Arfan; Launer, Lenore J.; Seshadri, Sudha; Hamilton-Bruce, Monica Anne; Jimenez-Conde, Jordi; Cole, John W.; Schmidt, Reinhold; Slowik, Agnieszka; Lemmens, Robin; Lindgren, Arne; Melander, Olle; Grewal, Raji P.; Sacco, Ralph L.; Rundek, Tatjana; Rexrode, Kathryn; Arnett, Donna K.; Johnson, Julie A.; Benavente, Oscar R.; Wasssertheil-Smoller, Sylvia; Lee, Jin-Moo; Pulit, Sara L.; Wong, Quenna; Rich, Stephen S.; Bakker, Paul I. W. de; McArdle, Patrick F.; Woo, Daniel; Anderson, Christopher D.; Xu, Huichun; Heitsch, Laura; Fornage, Myriam; Jern, Christina; Stefansson, Kari; Thorsteinsdottir, Unnur; Gretarsdottir, Solveig; Lewis, Cathryn M.; Sharma, Pankaj; Sudlow, Cathie L. M.; Rothwell, Peter M.; Boncoraglio, Giorgio B.; Thijs, Vincent; Levi, Chris; Meschia, James F.; Rosand, Jonathan; Kittner, Steven J.; Mitchell, Braxton D.; Dichgans, Martin; Worrall, Bradford B. und Markus, Hugh S.
(2017):
Genetic Variation at 16q24.2 Is Associated With Small Vessel Stroke.
In: Annals of Neurology, Bd. 81, Nr. 3: S. 383-394
[PDF, 532kB]
Larsson, Susanna C.; Traylor, Matthew; Malik, Rainer; Dichgans, Martin; Burgess, Stephen und Markus, Hugh S.
(2017):
Modifiable pathways in Alzheimer's disease: Mendelian randomisation analysis.
In: BMJ British Medical Journal, Bd. 359, j5375
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Rannikmäe, Kristiina; Sivakumaran, Vhinoth; Millar, Henry; Malik, Rainer; Anderson, Christopher D.; Chong, Mike; Dave, Tushar; Falcone, Guido J.; Fernandez-Cadenas, Israel; Jimenez-Conde, Jordi; Lindgren, Arne; Montaner, Joan; O'Donnell, Martin; Pare, Guillaume; Radmanesh, Farid; Rost, Natalia S.; Slowik, Agnieszka; Söderholm, Martin; Traylor, Matthew; Pulit, Sara L.; Seshadri, Sudha; Worrall, Brad B.; Woo, Daniel; Markus, Hugh S.; Mitchell, Braxton D.; Dichgans, Martin; Rosand, Jonathan und Sudlow, Cathie L. M.
(2017):
COL4A2 is associated with lacunar ischemic stroke and deep ICH Meta-analyses among 21,500 cases and 40,600 controls.
In: Neurology, Bd. 89, Nr. 17: S. 1829-1839
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Phuah, Chia-Ling; Dave, Tushar; Malik, Rainer; Raffeld, Miriam R.; Ayres, Alison M.; Goldstein, Joshua N.; Viswanathan, Anand; Greenberg, Steven M.; Jagiella, Jeremiasz M.; Hansen, Björn M.; Norrving, Bo; Jimenez-Conde, Jordi; Roquer, Jaume; Pichler, Alexander; Enzinger, Christian; Montaner, Joan; Fernandez-Cadenas, Israel; Lindgren, Arne; Slowik, Agnieszka; Schmidt, Reinhold; Biffi, Alessandro; Rost, Natalia; Langefeld, Carl D.; Markus, Hugh S.; Mitchell, Braxton D.; Worra, Brad B.; Kittner, Steven J.; Woo, Daniel; Dichgans, Martin; Rosand, Jonathan und Anderson, Christopher D.
(2017):
Genetic variants influencing elevated myeloperoxidase levels increase risk of stroke.
In: Brain, Bd. 140: S. 2663-2672
Lubitz, Steven A.; Parsons, Owen E.; Anderson, Christopher D.; Benjamin, Emelia J.; Malik, Rainer; Weng, Lu-Chen; Dichgans, Martin; Sudlow, Cathie L.; Rothwell, Peter M.; Rosand, Jonathan; Ellinor, Patrick T.; Markus, Hugh S. und Traylor, Matthew
(2017):
Atrial Fibrillation Genetic Risk and Ischemic Stroke Mechanisms.
In: Stroke, Bd. 48, Nr. 6: S. 1451-1456
Traylor, Matthew; Malik, Rainer und Dichgans, Martin
(2017):
Genetic variation at 16q24.2 is associated with small vessel stroke.
In: Annals of Neurology, Bd. 81, Nr. 3: S. 383-394
[PDF, 502kB]
Keenan, Tanya; Zhao, Wei; Rasheed, Asif; Ho, Weang K.; Malik, Rainer; Felix, Janine F.; Young, Robin; Shah, Nabi; Samuel, Maria; Sheikh, Nasir; Mucksavage, Megan L.; Shah, Omar; Li, Jin; Morley, Michael; Laser, Annika; Mallick, Nadeem Hayat; Zaman, Khan Shah; Ishaq, Mohammad; Rasheed, Syed Zahed; Memon, Fazal-ur-Rehman; Ahmed, Faisal; Hanif, Bashir; Lakhani, Muhammad Shakir; Fahim, Muhammad; Ishaq, Madiha; Shardha, Naresh Kumar; Ahmed, Naveeduddin; Mahmood, Khalid; Iqbal, Waseem; Akhtar, Saba; Raheel, Rabia; O'Donnell, Christopher J.; Hengstenberg, Christian; Maerz, Winifred; Kathiresan, Sekar; Samani, Nilesh; Goel, Anuj; Hopewell, Jemma C.; Chambers, John; Cheng, Yu-Ching; Sharma, Pankaj; Yang, Qiong; Rosand, Jonathan; Boncoraglio, Giorgio B.; Kazmi, Shahana Urooj; Hakonarson, Hakon; Köttgen, Anna; Kalogeropoulos, Andreas; Frossard, Philippe; Kamal, Ayeesha; Dichgans, Martin; Cappola, Thomas; Reilly, Muredach P.; Danesh, John; Rader, Daniel J.; Voight, Benjamin F. und Saleheen, Danish
(2016):
Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study.
In: Journal of the American College of Cardiology, Bd. 67, Nr. 4: S. 407-416
Laan, Sander W. van der; Fall, Tove; Soumaré, Aicha; Teumer, Alexander; Sedaghat, Sanaz; Baumert, Jens; Zabaneh, Delilah; Setten, Jessica van; Isgum, Ivana; Galesloot, Tessel E.; Arpegard, Johannes; Amouyel, Philippe; Trompet, Stella; Waldenberger, Melanie; Dörr, Marcus; Magnusson, Patrik K.; Giedraitis, Vilmantas; Larsson, Anders; Morris, Andrew P.; Felix, Janine F.; Morrison, Alanna C.; Franceschini, Nora; Bis, Joshua C.; Kavousi, Maryam; O'Donnell, Christopher; Drenos, Fotios; Tragante, Vinicius; Munroe, Patricia B.; Malik, Rainer; Dichgans, Martin; Worrall, Bradford B.; Erdmann, Jeanette; Nelson, Christopher P.; Samani, Nilesh J.; Schunkert, Heribert; Marchini, Jonathan; Patel, Riyaz S.; Hingorani, Aroon D.; Lind, Lars; Pedersen, Nancy L.; Graaf, Jacqueline de; Kiemeney, Lambertus A. L. M.; Baumeister, Sebastian E.; Franco, Oscar H.; Hofman, Albert; Uitterlinden, Andre G.; Koenig, Wolfgang; Meisinger, Christa; Peters, Annette; Thorand, Barbara; Jukema, J. Wouter; Eriksen, Bjorn Odvar; Toft, Ingrid; Wilsgaard, Tom; Onland-Moret, N. Charlotte; Schouw, Yvonne T. van der; Debette, Stéphanie; Kumari, Meena; Svensson, Per; Harst, Pim van der; Kivimaki, Mika; Keating, Brendan J.; Sattar, Naveed; Dehghan, Abbas; Reiner, Alex P.; Ingelsson, Erik; Ruijter, Hester M. den; dBakker, Paul I. W. de; Pasterkamp, Gerard; Arnlov, Johan; Holmes, Michael V. und Asselbergs, Folkert W.
(2016):
Cystatin C and Cardiovascular Disease A Mendelian Randomization Study.
In: Journal of the American College of Cardiology, Bd. 68, Nr. 9: S. 934-945
Dichgans, Martin; Wardlaw, Joanna; Smith, Eric; Zietemann, Vera; Seshadri, Sudha; Sachdev, Perminder; Biessels, Geert Jan; Fazekas, Franz; Benavente, Oscar; Pantoni, Leonardo; Deeuw, Frankerik de; Norrving, Bo; Matthews, Paul; Chen, Christopher; Mok, Vincent; Duering, Marco; Whiteley, Will; Shuler, Kirsten; Alonso, Alvaro; Black, Sandra E.; Brayne, Carol; Chabriat, Hugues; Cordonnier, Charlotte; Doubal, Fergus; Duzel, Emrah; Ewers, Michael; Frayne, Richard; Hachinski, Vladimir; Ikram, Mohammad Arfan; Jessen, Frank; Jouvent, Eric; Linn, Jennifer; O'Brien, John; Oostenbrugge, Robert van; Malik, Rainer; Mazoyer, Bernard; Schmidt, Reinhold; Sposato, Luciano A.; Stephan, Blossom; Swartz, Richard H.; Vernooij, Meike; Viswanathan, Anand; Werring, David; Abe, Koji; Allan, Louise; Arba, Francesco; Bae, Hee-Joon; Bath, Philip M. W.; Bordet, Regis; Breteler, Monique; Choi, Seong; Deary, Ian; DeCarli, Charles; Ebmeier, Klaus; Feng, Lei; Greenberg, Steven M.; Ihara, Masafumi; Kalaria, Rajesh; Kim, SanYun; Lim, Jae-Sung; Lindley, Richard I.; Mead, Gillian; Murray, Alison; Quinn, Terry; Ritchie, Craig; Sacco, Ralph; Salman, Rustam Al-Shahi; Sprigg, Nikola; Sudlow, Cathie; Thomas, Alan; Boxtel, Martin van; Grond, Jeroen van der; Lugt, Aad van der und Yang, Yuan-Han
(2016):
METACOHORTS for the study of vascular disease and its contribution to cognitive decline and neurodegeneration: An initiative of the Joint Programme for Neurodegenerative Disease Research.
In: Alzheimers & Dementia, Bd. 12, Nr. 12: S. 1235-1249
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Wollenweber, Frank Arne; Därr, Sonja; Müller, Claudia; Duering, Marco; Buerger, Katharina; Zietemann, Vera; Malik, Rainer; Brendel, Matthias; Ertl-Wagner, Birgit; Bartenstein, Peter; Rominger, Axel und Dichgans, Martin
(2016):
Prevalence of Amyloid Positron Emission Tomographic Positivity in Poststroke Mild Cognitive Impairment.
In: Stroke, Bd. 47, Nr. 10: S. 2645-2648
Harris, Sarah E.; Malik, Rainer; Marioni, Riccardo; Campbell, Archie; Seshadri, Sudha; Worrall, Bradford B.; Sudlow, Cathie L. M.; Hayward, Caroline; Bastin, Mark E.; Starr, John M.; Porteous, David J.; Wardlaw, Joanna M. und Deary, Ian J.
(2016):
Polygenic risk of ischemic stroke is associated with cognitive ability.
In: Neurology, Bd. 86, Nr. 7: S. 611-618
Williams, Stephen R.; Hsu, Fang-Chi; Keene, Keith L.; Chen, Wei-Min; Nelson, Sarah; Southerland, Andrew M.; Madden, Ebony B.; Coull, Bruce; Gogarten, Stephanie M.; Furie, Karen L.; Dzhivhuho, Godfrey; Rowles, Joe L.; Mehndiratta, Prachi; Malik, Rainer; Dupuis, Josée; Lin, Honghuang; Seshadri, Sudha; Rich, Stephen S.; Sale, Michèle M. und Worrall, Bradford B.
(2016):
Shared genetic susceptibility of vascular-related biomarkers with ischemic and recurrent stroke.
In: Neurology, Bd. 86, Nr. 4: S. 351-359
Malik, Rainer; Traylor, Matthew; Pulit, Sara L.; Bevan, Steve; Hopewell, Jemma C.; Holliday, Elizabeth G.; Zhao, Wei; Abrantes, Patricia; Amouyel, Philippe; Attia, John R.; Battey, Thomas W. K.; Berger, Klaus; Boncoraglio, Giorgio B.; Chauhan, Ganesh; Cheng, Yu-Ching; Chen, Wei-Min; Clarke, Robert; Cotlarciuc, Ioana; Debette, Stephanie; Falcone, Guido J.; Ferro, Jose M.; Gamble, Dale M.; Ilinca, Andreea; Kittner, Steven J.; Kourkoulis, Christina E.; Lemmens, Robin; Levi, Christopher R.; Lichtner, Peter; Lindgren, Arne; Liu, Jingmin; Meschia, James F.; Mitchell, Braxton D.; Oliveira, Sofia A.; Pera, Joana; Reiner, Alex P.; Rothwell, Peter M.; Sharma, Pankaj; Slowik, Agnieszka; Sudlow, Cathie L. M.; Tatlisumak, Turgut; Thijs, Vincent; Vicente, Astrid M.; Woo, Daniel; Seshadri, Sudha; Saleheen, Danish; Rosand, Jonathan; Markus, Hugh S.; Worrall, Bradford B. und Dichgans, Martin
(2016):
Low-frequency and common genetic variation in ischemic stroke The METASTROKE collaboration.
In: Neurology, Bd. 86, Nr. 13: S. 1217-1226
Gormley, Padhraig; Anttila, Verneri; Winsvold, Bendik S.; Palta, Priit; Esko, Tonu; Pers, Tune H.; Farh, Kai-How; Cuenca-Leon, Ester; Muona, Mikko; Furlotte, Nicholas A.; Kurth, Tobias; Ingason, Andres; McMahon, George; Ligthart, Lannie; Terwindt, Gisela M.; Kallela, Mikko; Freilinger, Tobias M.; Ran, Caroline; Gordon, Scott G.; Stam, Anine H.; Steinberg, Stacy; Borck, Guntram; Koiranen, Markku; Quaye, Lydia; Adams, Hieab H. H.; Lehtimäki, Terho; Sarin, Antti-Pekka; Wedenoja, Juho; Hinds, David A.; Buring, Julie E.; Schürks, Markus; Ridker, Paul M.; Hrafnsdottir, Maria Gudlaug; Stefansson, Hreinn; Ring, Susan M.; Hottenga, Jouke-Jan; Penninx, Brenda W. J. H.; Färkkilä, Markus; Artto, Ville; Kaunisto, Mari; Vepsäläinen, Salli; Malik, Rainer; Heath, Andrew C.; Madden, Pamela A. F.; Martin, Nicholas G.; Montgomery, Grant W.; Kurki, Mitja I.; Kals, Mart; Mägi, Reedik; Pärn, Kalle; Hämäläinen, Eija; Huang, Hailiang; Byrnes, Andrea E.; Franke, Lude; Huang, Jie; Stergiakouli, Evie; Lee, Phil H.; Sandor, Cynthia; Webber, Caleb; Cader, Zameel; Müller-Myhsok, Bertram; Schreiber, Stefan; Meitinger, Thomas; Eriksson, Johan G.; Salomaa, Veikko; Heikkila, Kauko; Loehrer, Elizabeth; Uitterlinden, Andre G.; Hofman, Albert; Duijn, Cornelia M. van; Cherkas, Lynn; Pedersen, Linda M.; Stubhaug, Audun; Nielsen, Christopher S.; Männikkö, Minna; Mihailov, Evelin; Milani, Lili; Göbel, Hartmut; Esserlind, Ann-Louise; Christensen, Anne Francke; Hansen, Thomas Folkmann; Werge, Thomas; Kaprio, Jaakko; Aromaa, Arpo J.; Raitakari, Olli; Ikram, M. Arfan; Spector, Tim; Järvelin, Marjo-Riitta; Metspalu, Andres; Kubisch, Christian; Strachan, David P.; Ferrari, Michel D.; Belin, Andrea C.; Dichgans, Martin; Wessman, Maija; Maagdenberg, Arn M. J. M. van den; Zwart, John-Anker; Boomsma, Dorret I.; Smith, George Davey; Stefansson, Kari; Eriksson, Nicholas; Daly, Mark J.; Neale, Benjamin M.; Olesen, Jes; Chasman, Daniel I.; Nyholt, Dale R. und Palotie, Aarno
(2016):
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.
In: Nature Genetics, Bd. 48, Nr. 8: S. 856-866
Pasterkamp, Gerard; Laan, Sander W. van der; Haitjema, Saskia; Asl, Hassan Foroughi; Siemelink, Marten A.; Bezemer, Tim; Setten, Jessica van; Dichgans, Martin; Malik, Rainer; Worrall, Bradford B.; Schunkert, Heribert; Samani, Nilesh J.; Kleijn, Dominique P. V. de; Markus, Hugh S.; Hoefer, Imo E.; Michoel, Tom; Jager, Saskia C. A. de; Björkegren, Johan L. M.; Ruijter, Hester M. den und Asselbergs, Folkert W.
(2016):
Human Validation of Genes Associated With a Murine Atherosclerotic Phenotype.
In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 36, Nr. 6: S. 1240-1246
Cheng, Yu-Ching; Stanne, Tara M.; Giese, Anne-Katrin; Ho, Weang Kee; Traylor, Matthew; Amouyel, Philippe; Holliday, Elizabeth G.; Malik, Rainer; Xu, Huichun; Kittner, Steven J.; Cole, John W.; O'Connell, Jeffrey R.; Danesh, John; Rasheed, Asif; Zhao, Wei; Engelter, Stefan; Grond-Ginsbach, Caspar; Kamatani, Yoichiro; Lathrop, Mark; Leys, Didier; Thijs, Vincent; Metso, Tiina M.; Tatlisumak, Turgut; Pezzini, Alessandro; Parati, Eugenio A.; Norrving, Bo; Bevan, Steve; Rothwell, Peter M.; Sudlow, Cathie; Slowik, Agnieszka; Lindgren, Arne; Walters, Matthew R.; Jannes, Jim; Shen, Jess; Crosslin, David; Doheny, Kimberly; Laurie, Cathy C.; Kanse, Sandip M.; Bis, Joshua C.; Fornage, Myriam; Mosley, Thomas H.; Hopewell, Jemma C.; Strauch, Konstantin; Müller-Nurasyid, Martina; Gieger, Christian; Waldenberger, Melanie; Peters, Annette; Meisinger, Christine; Ikram, M. Arfan; Longstreth, W. T.; Meschia, James F.; Seshadri, Sudha; Sharma, Pankaj; Worrall, Bradford; Jern, Christina; Levi, Christopher; Dichgans, Martin; Boncoraglio, Giorgio B.; Markus, Hugh S.; Debette, Stephanie; Rolfs, Arndt; Saleheen, Danish und Mitchell, Braxton D.
(2016):
Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2.
In: Stroke, Bd. 47, Nr. 2: S. 307-316
Traylor, Matthew; Rutten-Jacobs, Loes C. A.; Thijs, Vincent; Holliday, Elizabeth G.; Levi, Chris; Bevan, Steve; Malik, Rainer; Boncoraglio, Giorgio; Sudlow, Cathie; Rothwell, Peter M.; Dichgans, Martin und Markus, Hugh S.
(2016):
Genetic Associations With White Matter Hyperintensities Confer Risk of Lacunar Stroke.
In: Stroke, Bd. 47, Nr. 5: S. 1174-1179
Haffner, Christof; Malik, Rainer und Dichgans, Martin
(2016):
Genetic factors in cerebral small vessel disease and their impact on stroke and dementia.
In: Journal of Cerebral Blood Flow and Metabolism, Bd. 36, Nr. 1: S. 158-171
Gesierich, Benno; Opherk, Christian; Rosand, Jonathan; Gonik, Mariya; Malik, Rainer; Jouvent, Eric; Herve, Dominique; Adib-Samii, Poneh; Bevan, Steve; Pianese, Luigi; Silvestri, Serena; Dotti, Maria T.; De Stefano, Nicola; Grond, Jeroen van der; Boon, Elles M. J.; Pescini, Francesca; Rost, Natalia; Pantoni, Leonardo; Oberstein, Saskia A. Lesnik; Federico, Antonio; Ragno, Michele; Markus, Hugh S.; Tournier-Lasserve, Elisabeth; Chabriat, Hugues; Dichgans, Martin; Duering, Marco und Ewers, Michael
(2016):
APOE 2 is associated with white matter hyperintensity volume in CADASIL.
In: Journal of Cerebral Blood Flow and Metabolism, Bd. 36, Nr. 1: S. 199-203
Hinds, David A.; Buil, Alfonso; Ziemek, Daniel; Martinez-Perez, Angel; Malik, Rainer; Folkersen, Lasse; Germain, Marine; Mälarstig, Anders; Brown, Andrew; Manuel Soria, Jose; Dichgans, Martin; Bing, Nan; Franco-Cereceda, Anders; Carlos Souto, Juan; Dermitzakis, Emmanouil T.; Hamsten, Anders; Worrall, Bradford B.; Tung, Joyce Y. und Sabater-Lleal, Maria
(2016):
Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis.
In: Human Molecular Genetics, Bd. 25, Nr. 9: S. 1867-1874
Carrera, Caty; Jiménez-Conde, Jordi; Derdak, Sophia; Rabionet, Kelly; Vives-Bauza, Cristofol; Soriano-Tarrega, Carolina; Giralt-Steinhauer, Eva; Mola-Caminal, Marina; Diaz-Navarro, Rosa M.; Tur, Silvia; Muiño, Elena; Gallego-Fabrega, Cristina; Beltran, Sergi; Roquer, Jaume; Ruiz, Agustin; Sotolongo-Grau, Oscar; Krupinski, Jurek; Lee, Jin-Moo; Cruchaga, Carlos; Delgado, Pilar; Malik, Rainer; Worrall, Brad B.; Seshadri, Sudha; Montaner, Joan und Fernández-Cadenas, Israel
(2016):
Whole exome sequencing analysis reveals TRPV3 as a risk factor for cardioembolic stroke.
In: Thrombosis and Haemostasis, Bd. 116, Nr. 6: S. 1165-1171
Zhao, Huiying; Eising, Else; Vries, Boukje de; Vijfhuizen, Lisanne S.; Anttila, Verneri; Winsvold, Bendik S.; Kurth, Tobias; Stefansson, Hreinn; Kallela, Mikko; Malik, Rainer; Stam, Anine H.; Ikram, M. Arfan; Ligthart, Lannie; Freilinger, Tobias; Alexander, Michael; Müller-Myhsok, Bertram; Schreiber, Stefan; Meitinger, Thomas; Aromas, Arpo; Eriksson, Johan G.; Boomsma, Dorret I.; Duijn, Cornelia M. van; Zwart, John-Anker; Quaye, Lydia; Kubisch, Christian; Dichgans, Martin; Wessman, Maija; Stefansson, Kari; Chasman, Daniel I.; Palotie, Aarno; Martin, Nicholas G.; Montgomery, Grant W.; Ferrari, Michel D.; Terwindt, Gisela M.; Maagdenberg, Arn M. J. M. van den und Nyholt, Dale R.
(2016):
Gene-based pleiotropy across migraine with aura and migraine without aura patient groups.
In: Cephalalgia, Bd. 36, Nr. 7: S. 648-657
[PDF, 179kB]
Malik, Rainer; Winsvold, Bendik; Auffenberg, Eva; Dichgans, Martin und Freilinger, Tobias
(2016):
The migraine–stroke connection: A genetic perspective.
In: Cephalalgia, Bd. 36, Nr. 7: S. 658-668
[PDF, 188kB]
Nyholt, Dale R.; Anttila, Verneri; Winsvold, Bendik S.; Kurth, Tobias; Stefansson, Hreinn; Kallela, Mikko; Malik, Rainer; Vries, Boukje de; Terwindt, Gisela M.; Arfan Ikram, M.; Stam, Anine H.; Ligthart, Lannie; Freilinger, Tobias; Alexander, Michael; Müller-Myhsok, Bertram; Schreiber, Stefan; Meitinger, Thomas; Aromaa, Arpo J.; Eriksson, Johan G.; Kaprio, Jaakko; Boomsma, Dorret I.; Duijn, Cornelia van; Raitakari, Olli; Jarvelin, Marjo-Riitta; Zwart, John-Anker; Quaye, Lydia; Strachan, David P.; Kubisch, Christian; Ferrari, Michel D.; Maagdenberg, Arn M. J. M. van den; Dichgans, Martin; Wessman, Maija; Smith, George Davey; Stefansson, Kari; Chasman, Daniel I. und Palotie, Aarno
(Mai 2015):
Concordance of genetic risk across migraine subgroups: Impact on current and future genetic association studies.
In: Cephalalgia, Bd. 35, Nr. 6: S. 489-499
[PDF, 178kB]
Leong, Aaron; Rehman, Waheed; Dastani, Zari; Greenwood, Celia; Timpson, Nicholas; Langsetmo, Lisa; Berger, Claudie; Fu, Lei; Wong, Betty Y. L.; Malik, Suneil; Malik, Rainer; Hanley, David A.; Cole, David E. C.; Goltzman, David und Richards, J. Brent
(2014):
The Causal Effect of Vitamin D Binding Protein (DBP) Levels on Calcemic and Cardiometabolic Diseases: A Mendelian Randomization Study.
In: PLOS Medicine 11(10), e1001751 [PDF, 265kB]
In: PLOS Medicine 11(10), e1001751 [PDF, 265kB]
Traylor, Matthew; Mäkelä, Kari-Matti; Kilarski, Laura L.; Holliday, Elizabeth G.; Devan, William J.; Nalls, Mike A.; Wiggins, Kerri L.; Zhao, Wei; Cheng, Yu-Ching; Achterberg, Sefanja; Malik, Rainer; Sudlow, Cathie; Bevan, Steve; Raitoharju, Emma; Oksala, Niku; Thijs, Vincent; Lemmens, Robin; Lindgren, Arne; Slowik, Agnieszka; Maguire, Jane M.; Walters, Matthew; Algra, Ale; Sharma, Pankaj; Attia, John R.; Boncoraglio, Giorgio B.; Rothwell, Peter M.; Bakker, Paul I. W. de; Bis, Joshua C.; Saleheen, Danish; Kittner, Steven J.; Mitchell, Braxton D.; Rosand, Jonathan; Meschia, James F.; Levi, Christopher; Dichgans, Martin; Lehtimäki, Terho; Lewis, Cathryn M. und Markus, Hugh S.
(2014):
A Novel MMP12 Locus Is Associated with Large Artery Atherosclerotic Stroke Using a Genome-Wide Age-at-Onset Informed Approach.
In: PLOS Genetics 10(7), e1004469 [PDF, 1MB]
In: PLOS Genetics 10(7), e1004469 [PDF, 1MB]
de Vries, Boukje; Freilinger, Tobias; Anttila, Verneri; Malik, Rainer; Kallela, Mikko; Terwindt, Gisela M.; Pozo-Rosich, Patricia; Winsvold, Bendik; Nyholt, Dale R.; van Oosterhout, Willebrordus P. J.; Artto, Ville; Todt, Unda; Hamalainen, Eija; Fernandez-Morales, Jessica; Louter, Mark A.; Kaunisto, Mari A.; Schoenen, Jean; Raitakari, Olli; Lehtimaki, Terho; Vila-Pueyo, Marta; Goebel, Hartmut; Wichmann, Erich; Sintas, Celia; Uitterlinden, Andre G.; Hofman, Albert; Rivadeneira, Fernando; Heinze, Axel; Tronvik, Erling; Van Duijn, Cornelia M.; Kaprio, Jaakko; Cormand, Bru; Wessman, Maija; Frants, Rune R.; Meitinger, Thomas; Mueller-Myhsok, Bertram; Zwart, John-Anker; Farkkila, Markus; Macaya, Alfons; Ferrari, Michel D.; Kubisch, Christian; Palotie, Aarno; Dichgans, Martin und van den Maagdenberg, Arn M. J. M.
(2013):
Migraine without aura: genome-wide association analysis identifies several novel susceptibility.
In: The Journal of Headache and Pain, Bd. 14, P18
[PDF, 134kB]