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Eine Ebene höherGruppiert nach: Dokumententyp |
Veröffentlichungsdatum
Anzahl der Publikationen: 5
2020
Sellmer, Andreas; Pilsl, Bernadette; Beyer, Mandy; Pongratz, Herwig; Wirth, Lukas; Elz, Sigurd; Dove, Stefan; Henninger, Sven Julian; Spiekermann, Karsten; Polzer, Harald; Klaeger, Susan; Kuster, Bernhard; Boehmer, Frank D.; Fiebig, Heinz-Herbert; Kraemer, Oliver H. und Mahboobi, Siavosh
(2020):
A series of novel aryl-methanone derivatives as inhibitors of FMS-like tyrosine kinase 3 (FLT3) in FLT3-ITD-positive acute myeloid leukemia.
In: European Journal of Medicinal Chemistry, Bd. 193, 112232
2017
Kläger, Susan; Heinzlmeir, Stephanie; Wilhelm, Mathias; Polzer, Harald; Vick, Binje; König, Paul-Albert; Reinecke, Maria; Ruprecht, Benjamin; Petzoldt, Svenja; Meng, Chen; Zecha, Jana; Reiter, Katrin; Qiao, Huichao; Helm, Dominic; Koch, Heiner; Schoof, Melanie; Canevari, Giulia; Casale, Elena; Depaolini, Stefania Re; Feuchtinger, Annette; Wu, Zhixiang; Schmidt, Tobias; Rückert, Lars; Becker, Wilhelm; Hünges, Jan; Garz, Anne-Kathrin; Gohlke, Björn-Oliver; Zolg, Daniel Paul; Kayser, Gian; Vooder, Tonu; Preissner, Robert; Hahne, Hannes; Tonisson, Neeme; Kramer, Karl; Götze, Katharina; Bassermann, Florian; Schlegl, Judith; Ehrlich, Hans-Christian; Aiche, Stephan; Walch, Axel; Greif, Philipp A.; Schneider, Sabine; Felder, Eduard Rudolf; Ruland, Jürgen; Medard, Guillaume; Jeremias, Irmela; Spiekermann, Karsten und Kuster, Bernhard
(2017):
The target landscape of clinical kinase drugs.
In: Science, Bd. 358, Nr. 6367, eaan4368
2016
Sandhöfer, Nadine; Bauer, Julia; Reiter, Katrin; Dufour, Annika; Rothenberg, Maja; Konstandin, Nikola P.; Zellmeier, Evelyn; Tizazu, Belay; Greif, Philipp A.; Metzeler, Klaus H.; Hiddemann, Wolfgang; Polzer, Harald und Spiekermann, Karsten
(2016):
The new and recurrent FLT3 juxtamembrane deletion mutation shows a dominant negative effect on the wild-type FLT3 receptor.
In: Scientific Reports, Bd. 6, 28032
[PDF, 846kB]
2015
Sironi, Silvia; Wagner, Michaela; Kuett, Alexander; Drolle, Heidrun; Polzer, Harald; Spiekermann, Karsten; Rieger, Christina und Fiegl, Michael
(2015):
Microenvironmental Hypoxia regulates FLT3 expression and biology in AML.
In: Scientific Reports, Bd. 5, 17550
[PDF, 1MB]
2014
Janke, Hanna; Pastore, Friederike; Schumacher, Daniela; Herold, Tobias; Hopfner, Karl-Peter; Schneider, Stephanie; Berdel, Wolfgang E.; Büchner, Thomas; Woermann, Bernhard J.; Subklewe, Marion; Bohlander, Stefan K.; Hiddemann, Wolfgang; Spiekermann, Karsten und Polzer, Harald
(2014):
Activating FLT3 Mutants Show Distinct Gain-of-Function Phenotypes In Vitro and a Characteristic Signaling Pathway Profile Associated with Prognosis in Acute Myeloid Leukemia.
In: PLOS ONE 9(3), e89560 [PDF, 2MB]
In: PLOS ONE 9(3), e89560 [PDF, 2MB]