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Veröffentlichungsdatum
Anzahl der Publikationen: 24
2024
Tamalunas, Alexander 
ORCID: https://orcid.org/0000-0002-4659-2262; Wendt, Amin; Springer, Florian; Vigodski, Victor; Trieb, Moritz; Eitelberger, Nikolaus; Poth, Henrik; Ciotkowska, Anna; Rutz, Beata; Hu, Sheng; Schulz, Heiko; Ledderose, Stephan ORCID: https://orcid.org/0000-0001-7313-2088; Rogenhofer, Nina; Kolben, Thomas; Nössner, Elfriede; Stief, Christian G. ORCID: https://orcid.org/0000-0003-3291-9460 und Hennenberg, Martin ORCID: https://orcid.org/0000-0003-1305-6727
(2024):
Immunomodulatory imide drugs inhibit human detrusor smooth muscle contraction and growth of human detrusor smooth muscle cells, and exhibit vaso-regulatory functions.
In: Biomedicine & Pharmacotherapy, Bd. 177, 117066
[PDF, 7MB]
ORCID: https://orcid.org/0000-0002-4659-2262; Wendt, Amin; Springer, Florian; Vigodski, Victor; Trieb, Moritz; Eitelberger, Nikolaus; Poth, Henrik; Ciotkowska, Anna; Rutz, Beata; Hu, Sheng; Schulz, Heiko; Ledderose, Stephan ORCID: https://orcid.org/0000-0001-7313-2088; Rogenhofer, Nina; Kolben, Thomas; Nössner, Elfriede; Stief, Christian G. ORCID: https://orcid.org/0000-0003-3291-9460 und Hennenberg, Martin ORCID: https://orcid.org/0000-0003-1305-6727
(2024):
Immunomodulatory imide drugs inhibit human detrusor smooth muscle contraction and growth of human detrusor smooth muscle cells, and exhibit vaso-regulatory functions.
In: Biomedicine & Pharmacotherapy, Bd. 177, 117066
[PDF, 7MB]
2022
Tamalunas, Alexander; Wendt, Amin; Springer, Florian; Vigodski, Victor; Ciotkowska, Anna; Rutz, Beata; Wang, Ruixiao; Huang, Ru; Liu, Yuhan; Schulz, Heiko; Ledderose, Stephan; Kolben, Thomas; Magistro, Giuseppe; Stief, Christian G. und Hennenberg, Martin
(2022):
Permixon (R), hexane-extracted Serenoa repens, inhibits human prostate and bladder smooth muscle contraction and exerts growth-related functions in human prostate stromal cells.
In: Life Sciences, Bd. 308, 120931
Tamalunas, Alexander; Wendt, Amin; Springer, Florian; Ciotkowska, Anna; Rutz, Beata; Wang, Ruixiao; Huang, Ru; Liu, Yuhan; Schulz, Heiko; Ledderose, Stephan; Magistro, Giuseppe; Stief, Christian G. und Hennenberg, Martin
(2022):
Inhibition of Human Prostate and Bladder Smooth Muscle Contraction, Vasoconstriction of Porcine Renal and Coronary Arteries, and Growth-Related Functions of Prostate Stromal Cells by Presumed Small Molecule G alpha(q/11) Inhibitor, YM-254890.
In: Frontiers in Physiology, Bd. 13
[PDF, 3MB]
2021
Wang, Ruixiao; Schneider, Stephanie; Keppler, Oliver T.; Li, Bingsheng; Rutz, Beata; Ciotkowska, Anna; Stief, Christian G. und Hennenberg, Martin
(2021):
ADP Ribosylation Factor 6 Promotes Contraction and Proliferation, Suppresses Apoptosis and Is Specifically Inhibited by NAV2729 in Prostate Stromal Cells.
In: Molecular Pharmacology, Bd. 100, Nr. 4: S. 356-371
Tamalunas, Alexander; Sauckel, Cora; Ciotkowska, Anna; Rutz, Beata; Wang, Ruixiao; Huang, Ru; Li, Bingsheng; Stief, Christian G.; Gratzke, Christian und Hennenberg, Martin
(2021):
Inhibition of human prostate stromal cell growth and smooth muscle contraction by thalidomide: A novel remedy in LUTS?
In: Prostate, Bd. 81, Nr. 7: S. 377-389
Tamalunas, Alexander; Sauckel, Cora; Ciotkowska, Anna; Rutz, Beata; Wang, Ruixiao; Huang, Ru; Li, Bingsheng; Stief, Christian G.; Gratzke, Christian und Hennenberg, Martin
(2021):
Lenalidomide and pomalidomide inhibit growth of prostate stromal cells and human prostate smooth muscle contraction.
In: Life Sciences, Bd. 281, 119771
Spek, Annabel; Li, Bingsheng; Rutz, Beata; Ciotkowska, Anna; Huang, Ru; Liu, Yuhan; Wang, Ruixiao; Strittmatter, Frank; Waidelich, Raphaela; Stief, Christian G. und Hennenberg, Martin
(2021):
Purinergic smooth muscle contractions in the human prostate: estimation of relevance and characterization of different agonists.
In: Naunyn-Schmiedebergs Archives of Pharmacology, Bd. 394, Nr. 6: S. 1113-1131
Spek, Annabel; Li, Bingsheng; Rutz, Beata; Ciotkowska, Anna; Huang, Ru; Liu, Yuhan; Wang, Ruixiao; Strittmatter, Frank; Waidelich, Raphaela; Stief, Christian G. und Hennenberg, Martin
(2021):
Purinergic smooth muscle contractions in the human prostate: estimation of relevance and characterization of different agonists.
In: Naunyn-Schmiedeberg's archives of pharmacology, Bd. 394, Nr. 6: S. 1113-1131
[PDF, 2MB]
2020
Wang, Ruixiao; Yu, Qingfeng; Wang, Xiaolong; Li, Bingsheng; Ciotkowska, Anna; Rutz, Beata; Wang, Yiming; Stief, Christian G. und Hennenberg, Martin
(2020):
Rac1 silencing, NSC23766 and EHT1864 reduce growth and actin organization of bladder smooth muscle cells.
In: Life Sciences, Bd. 261, 118468
Li, Bingsheng; Wang, Xiaolong; Rutz, Beata; Wang, Ruixiao; Tamalunas, Alexander; Strittmatter, Frank; Waidelich, Raphaela; Stief, Christian G. und Hennenberg, Martin
(2020):
The STK16 inhibitor STK16-IN-1 inhibits non-adrenergic and non-neurogenic smooth muscle contractions in the human prostate and the human male detrusor.
In: Naunyn-Schmiedebergs Archives of Pharmacology, Bd. 393, Nr. 5: S. 829-842
Li, Bingsheng; Wang, Xiaolong; Wang, Ruixiao; Rutz, Beata; Ciotkowska, Anna; Gratzke, Christian; Herlemann, Annika; Spek, Annabel; Tamalunas, Alexander; Waidelich, Raphaela; Stief, Christian G. und Hennenberg, Martin
(2020):
Inhibition of neurogenic and thromboxane A(2)-induced human prostate smooth muscle contraction by the integrin alpha 2 beta 1 inhibitor BTT-3033 and the integrin-linked kinase inhibitor Cpd22.
In: Prostate, Bd. 80, Nr. 11: S. 831-849
2019
Wang, Xiaolong; Wang, Yiming; Gratzke, Christian; Sterr, Christian; Yu, Qingfeng; Li, Bingsheng; Strittmatter, Frank; Herlemann, Annika; Tamalunas, Alexander; Rutz, Beata; Ciotkowska, Anna; Waidelich, Raphaela; Liu, Chunxiao; Stief, Christian G. und Hennenberg, Martin
(2019):
Ghrelin Aggravates Prostate Enlargement in Rats with Testosterone-Induced Benign Prostatic Hyperplasia, Stromal Cell Proliferation, and Smooth Muscle Contraction in Human Prostate Tissues.
In: Oxidative Medicine and Cellular Longevity, Bd. 2019, 4748312
[PDF, 2MB]
Yu, Qingfeng; Gratzke, Christian; Wang, Ruixiao; Li, Bingsheng; Kuppermann, Paul; Herlemann, Annika; Tamalunas, Alexander; Wang, Yiming; Rutz, Beata; Ciotkowska, Anna; Wang, Xiaolong; Strittmatter, Frank; Waidelich, Raphaela; Stief, Christian G. und Hennenberg, Martin
(2019):
A NAV2729-sensitive mechanism promotes adrenergic smooth muscle contraction and growth of stromal cells in the human prostate.
In: Journal of Biological Chemistry, Bd. 294, Nr. 32: S. 12231-12249
2018
Herlemann, Annika; Keller, Patrick; Schott, Melanie; Tamalunas, Alexander; Ciotkowska, Anna; Rutz, Beata; Wang, Yiming; Yu, Qingfeng; Waidelich, Raphaela; Strittmatter, Frank; Stief, Christian G.; Gratzke, Christian und Hennenberg, Martin
(2018):
Inhibition of smooth muscle contraction and ARF6 activity by the inhibitor for cytohesin GEFs, secinH3, in the human prostate.
In: American Journal of Physiology-Renal Physiology, Bd. 314, Nr. 1:
F47-F57
Yu, Qingfeng; Gratzke, Christian; Wang, Yiming; Herlemann, Annika; Strittmatter, Frank; Rutz, Beata; Stief, Christian G. und Hennenberg, Martin
(2018):
Inhibition of prostatic smooth muscle contraction by the inhibitor of G protein-coupled receptor kinase 2/3, CMPD101.
In: European Journal of Pharmacology, Bd. 831: S. 9-19
Hennenberg, Martin; Kuppermann, Paul; Yu, Qingfeng; Herlemann, Annika; Tamalunas, Alexander; Wang, Yiming; Rutz, Beata; Ciotkowska, Anna; Strittmatter, Frank; Stief, Christian G. und Gratzke, Christian
(2018):
Inhibition of Prostate Smooth Muscle Contraction by Inhibitors of Polo-Like Kinases.
In: Frontiers in Physiology, Bd. 9, 734
[PDF, 5MB]
Yu, Qingfeng; Gratzke, Christian; Wang, Yiming; Herlemann, Annika; Sterr, Christian Maximilian; Rutz, Beata; Ciotkowska, Anna; Wang, Xiaolong; Strittmatter, Frank; Stief, Christian G. und Hennenberg, Martin
(2018):
Inhibition of human prostate smooth muscle contraction by the LIM kinase inhibitors, SR7826 and LIMKi3.
In: British Journal of Pharmacology, Bd. 175, Nr. 11: S. 2077-2096
2017
Hennenberg, Martin; Acevedo, Alice; Wiemer, Nicolas; Kan, Aysenur; Tamalunas, Alexander; Wang, Yiming; Yu, Qingfeng; Rutz, Beata; Ciotkowska, Anna; Herlemann, Annika; Strittmatter, Frank; Stief, Christian G. und Gratzke, Christian
(2017):
Non-Adrenergic, Tamsulosin-Insensitive Smooth Muscle Contraction Is Sufficient to Replace alpha(1)-Adrenergic Tension in the Human Prostate.
In: Prostate, Bd. 77, Nr. 7: S. 697-707
Hennenberg, Martin; Tamalunas, Alexander; Wang, Yiming; Keller, Patrick; Schott, Melanie; Strittmatter, Frank; Herlemann, Annika; Yu, Qingfeng; Rutz, Beata; Ciotkowska, Anna; Stief, Christian G. und Gratzke, Christian
(2017):
Inhibition of agonist-induced smooth muscle contraction by picotamide in the male human lower urinary tract outflow region.
In: European Journal of Pharmacology, Bd. 803: S. 39-47
2016
Hennenberg, Martin; Schott, Melanie; Kan, Aysenur; Keller, Patrick; Tamalunas, Alexander; Ciotkowska, Anna; Rutz, Beata; Wang, Yiming; Strittmatter, Frank; Herlemann, Annika; Yu, Qingfeng; Stief, Christian G. und Gratzke, Christian
(2016):
Inhibition of Adrenergic and Non-Adrenergic Smooth Muscle Contraction in the Human Prostate by the Phosphodiesterase 10-Selective Inhibitor TC-E 5005.
In: Prostate, Bd. 76, Nr. 15: S. 1364-1374
Wang, Yiming; Gratzke, Christian; Tamalunas, Alexander; Rutz, Beata; Ciotkowska, Anna; Strittmatter, Frank; Herlemann, Annika; Janich, Sophie; Waidelich, Raphaela; Liu, Chunxiao; Stief, Christian G. und Hennenberg, Martin
(2016):
Smooth muscle contraction and growth of stromal cells in the human prostate are both inhibited by the Src family kinase inhibitors, AZM475271 and PP2.
In: British Journal of Pharmacology, Bd. 173, Nr. 23: S. 3342-3358
Wang, Yiming; Gratzke, Christian; Tamalunas, Alexander; Wiemer, Nicolas; Ciotkowska, Anna; Rutz, Beata; Waidelich, Raphaela; Strittmatter, Frank; Liu, Chunxiao; Stief, Christian G. und Hennenberg, Martin
(2016):
P21-Activated Kinase Inhibitors FRAX486 and IPA3: Inhibition of Prostate Stromal Cell Growth and Effects on Smooth Muscle Contraction in the Human Prostate.
In: PLOS ONE 11(4), e0153312 [PDF, 5MB]
In: PLOS ONE 11(4), e0153312 [PDF, 5MB]
2013
Hennenberg, Martin; Strittmatter, Frank; Schmetkamp, Henning; Rutz, Beata; Walther, Sebastian; Stief, Christian G. und Gratzke, Christian
(2013):
The cAMP effector EPAC activates Elk1 transcription factor in prostate smooth muscle, and is a minor regulator of alpha 1-adrenergic contraction.
In: Journal of Biomedical Science
20:46
[PDF, 2MB]
2012
Hennenberg, Martin; Strittmatter, Frank; Beckmann, Christer; Rutz, Beata; Füllhase, Claudius; Waidelich, Raphaela; Montorsi, Francesco; Hedlund, Petter; Andersson, Karl-Erik; Stief, Christian Georg und Gratzke, Christian
(2012):
Silodosin inhibits noradrenaline-activated transcription factors Elk1 and SRF in human prostate smooth muscle.
In: PLOS ONE 7(11), e50904 [PDF, 1MB]
In: PLOS ONE 7(11), e50904 [PDF, 1MB]