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Anzahl der Publikationen: 18
Zeitschriftenartikel
Biel, Davina; Suarez-Calvet, Marc; Hager, Paul; Rubinski, Anna; Dewenter, Anna; Steward, Anna; Roemer, Sebastian; Ewers, Michael; Haass, Christian; Brendel, Matthias und Franzmeier, Nicolai
(2023):
sTREM2 is associated with amyloid-related p-tau increases and glucose hypermetabolism in Alzheimer's disease.
In: EMBO Molecular Medicine, Bd. 15, Nr. 2
[PDF, 1MB]
Morenas-Rodriguez, Estrella; Li, Yan; Nuscher, Brigitte; Franzmeier, Nicolai; Xiong, Chengjie; Suarez-Calvet, Marc; Fagan, Anne M.; Schultz, Stephanie; Gordon, Brian A.; Benzinger, Tammie L. S.; Hassenstab, Jason; McDade, Eric; Feederle, Regina; Karch, Celeste M.; Schlepckow, Kai; Morris, John C.; Kleinberger, Gernot; Nellgard, Bengt; Voglein, Jonathan; Blennow, Kaj; Zetterberg, Henrik; Ewers, Michael; Jucker, Mathias; Levin, Johannes; Bateman, Randall J. und Haass, Christian
(2022):
Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study.
In: Lancet Neurology, Bd. 21, Nr. 4: S. 329-341
[PDF, 761kB]
Ali, Muhammad M.; Sung, Yun Ju; Wang, Fengxian; Fernandez, Maria; Morris, John M.; Fagan, Anne; Blennow, Kaj; Zetterberg, Henrik; Heslegrave, Amanda; Johansson, Per; Svensson, Johan; Nellgard, Bengt; Lleo, Alberto; Alcolea, Daniel; Clarimon, Jordi; Rami, Lorena; Molinuevo, Jose Luis; Suarez-Calvet, Marc; Morenas-Rodriguez, Estrella R.; Kleinberger, Gernot J.; Haass, Christian; Ewers, Michael; Levin, Johannes; Farlow, Martin; Perrin, Richard und Cruchaga, Carlos
(2022):
Leveraging large multi-center cohorts of Alzheimer disease endophenotypes to understand the role of Klotho heterozygosity on disease risk.
In: PLOS One 17(5), e0267298 [PDF, 1MB]
In: PLOS One 17(5), e0267298 [PDF, 1MB]
Franzmeier, Nicolai; Ren, Jinyi; Damm, Alexander; Monte-Rubio, Gemma; Boada, Merce; Ruiz, Agustin; Ramirez, Alfredo; Jessen, Frank; Duezel, Emrah; Rodriguez Gomez, Octavio; Benzinger, Tammie; Goate, Alison; Karch, Celeste M.; Fagan, Anne M.; McDade, Eric; Buerger, Katharina; Levin, Johannes; Duering, Marco; Dichgans, Martin 
ORCID: https://orcid.org/0000-0002-0654-387X; Suarez-Calvet, Marc; Haass, Christian; Gordon, Brian A.; Lim, Yen Ying; Masters, Colin L.; Janowitz, Daniel; Catak, Cihan; Wolfsgruber, Steffen; Wagner, Michael; Milz, Esther; Moreno-Grau, Sonia; Teipel, Stefan; Grothe, Michel J.; Kilimann, Ingo; Rossor, Martin; Fox, Nick; Laske, Christoph; Chhatwal, Jasmeer; Falkai, Peter; Perneczky, Robert; Lee, Jae-Hong; Spottke, Annika; Boecker, Henning; Brosseron, Frederic; Fliessbach, Klaus; Heneka, Michael T.; Nestor, Peter; Peters, Oliver; Fuentes, Manuel; Menne, Felix; Priller, Josef; Spruth, Eike J.; Franke, Christiana; Schneider, Anja; Westerteicher, Christine; Speck, Oliver; Wiltfang, Jens; Bartels, Claudia; Araque Caballero, Miguel angel; Metzger, Coraline; Bittner, Daniel; Salloway, Stephen; Danek, Adrian; Hassenstab, Jason; Yakushev, Igor; Schofield, Peter R.; Morris, John C.; Bateman, Randall J. und Ewers, Michael
(2021):
The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease.
In: Molecular Psychiatry, Bd. 26, Nr. 2: S. 614-628
[PDF, 2MB]
ORCID: https://orcid.org/0000-0002-0654-387X; Suarez-Calvet, Marc; Haass, Christian; Gordon, Brian A.; Lim, Yen Ying; Masters, Colin L.; Janowitz, Daniel; Catak, Cihan; Wolfsgruber, Steffen; Wagner, Michael; Milz, Esther; Moreno-Grau, Sonia; Teipel, Stefan; Grothe, Michel J.; Kilimann, Ingo; Rossor, Martin; Fox, Nick; Laske, Christoph; Chhatwal, Jasmeer; Falkai, Peter; Perneczky, Robert; Lee, Jae-Hong; Spottke, Annika; Boecker, Henning; Brosseron, Frederic; Fliessbach, Klaus; Heneka, Michael T.; Nestor, Peter; Peters, Oliver; Fuentes, Manuel; Menne, Felix; Priller, Josef; Spruth, Eike J.; Franke, Christiana; Schneider, Anja; Westerteicher, Christine; Speck, Oliver; Wiltfang, Jens; Bartels, Claudia; Araque Caballero, Miguel angel; Metzger, Coraline; Bittner, Daniel; Salloway, Stephen; Danek, Adrian; Hassenstab, Jason; Yakushev, Igor; Schofield, Peter R.; Morris, John C.; Bateman, Randall J. und Ewers, Michael
(2021):
The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease.
In: Molecular Psychiatry, Bd. 26, Nr. 2: S. 614-628
[PDF, 2MB]
Ende, Emma L. van der; Morenas-Rodriguez, Estrella; McMillan, Corey; Grossman, Murray; Irwin, David; Sanchez-Valle, Raquel; Graff, Caroline; Vandenberghe, Rik; Pijnenburg, Yolande A. L.; Laforce, Robert; Le Ber, Isabelle; Lleo, Alberto; Haass, Christian; Suarez-Calvet, Marc; Swieten, John C. van und Seelaar, Harro
(2021):
CSF sTREM2 is elevated in a subset in GRN-related frontotemporal dementia.
In: Neurobiology of Aging, Bd. 103
[PDF, 513kB]
Ewers, Michael; Biechele, Gloria; Suarez-Calvet, Marc; Sacher, Christian; Blume, Tanja; Morenas-Rodriguez, Estrella; Deming, Yuetiva; Piccio, Laura; Cruchaga, Carlos; Kleinberger, Gernot; Shaw, Leslie; Trojanowski, John Q.; Herms, Jochen; Dichgans, Martin; Brendel, Matthias; Haass, Christian und Franzmeier, Nicolai
(2020):
Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation.
In: EMBO Molecular Medicine, Bd. 12, Nr. 9, e12308
Abdelhak, Ahmed; Hottenrott, Tilman; Morenas-Rodriguez, Estrella; Suarez-Calvet, Marc; Zettl, Uwe K.; Haass, Christian; Meuth, Sven G.; Rauer, Sebastian; Otto, Markus; Tumani, Hayrettin und Huss, Andre
(März 2019):
Glial Activation Markers in CSF and Serum From Patients With Primary Progressive Multiple Sclerosis: Potential of Serum GFAP as Disease Severity Marker?
In: Frontiers in Neurology, Bd. 10, 280: S. 1-9
[PDF, 1MB]
Deming, Yuetiva; Filipello, Fabia; Cignarella, Francesca; Cantoni, Claudia; Hsu, Simon; Mikesell, Robert; Li, Zeran; Del-Aguila, Jörge L.; Dube, Umber; Farias, Fabiana Geraldo; Bradley, Joseph; Budde, John; Ibanez, Laura; Fernandez, Maria Victoria; Blennow, Kaj; Zetterberg, Henrik; Heslegrave, Amanda; Johansson, Per M.; Svensson, Johan; Nellgard, Bengt; Lleo, Alberto; Alcolea, Daniel; Clarimon, Jordi; Rami, Lorena; Molinuevo, Jose Luis; Suarez-Calvet, Marc; Morenas-Rodriguez, Estrella; Kleinberger, Gernot; Ewers, Michael; Harari, Oscar; Haass, Christian; Brett, Thomas J.; Benitez, Bruno A.; Karch, Celeste M.; Piccio, Laura und Cruchaga, Carlos
(2019):
The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk.
In: Science Translational Medicine, Bd. 11, Nr. 505, eaau2291
[PDF, 1MB]
Morenas-Rodriguez, Estrella; Alcolea, Daniel; Suarez-Calvet, Marc; Munoz-Llahuna, Laia; Vilaplana, Eduard; Sala, Isabel; Subirana, Andrea; Querol-Vilaseca, Marta; Carmona-Iragui, Maria; Illan-Gala, Ignacio; Ribosa-Nogue, Roser; Blesa, Rafael; Haass, Christian; Fortea, Juan und Lleo, Alberto
(2019):
Different pattern of CSF glial markers between dementia with Lewy bodies and Alzheimer's disease.
In: Scientific Reports, Bd. 9, 7803
[PDF, 2MB]
Suarez-Calvet, Marc; Morenas-Rodriguez, Estrella; Kleinberger, Gernot; Schlepckow, Kai; Caballero, Miguel Angel Araque; Franzmeier, Nicolai; Capell, Anja; Fellerer, Katrin; Nuscher, Brigitte; Eren, Erden; Levin, Johannes; Deming, Yuetiva; Piccio, Laura; Karch, Celeste M.; Cruchaga, Carlos; Shaw, Leslie M.; Trojanowski, John Q.; Weiner, Michael; Ewers, Michael und Haass, Christian
(2019):
Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid- pathology.
In: Molecular Neurodegeneration, Bd. 14, 1
[PDF, 1MB]
Falcon, Caries; Monte-Rubio, Gemma C.; Grau-Rivera, Oriol; Suarez-Calvet, Marc; Sanchez-Valle, Raquel; Rami, Lorena; Bosch, Beatriz; Haass, Christian; Domingo Gispert, Juan und Luis Molinuevo, Jose
(2019):
CSF glial biomarkers YKL40 and sTREM2 are associated with longitudinal volume and diffusivity changes in cognitively unimpaired individuals.
In: Neuroimage-Clinical, Bd. 23, UNSP 101801
[PDF, 2MB]
Ewers, Michael; Franzmeier, Nicolai; Suarez-Calvet, Marc; Morenas-Rodriguez, Estrella; Caballero, Miguel Angel Araque; Kleinberger, Gernot; Piccio, Laura; Cruchaga, Carlos; Deming, Yuetiva; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Trojanowski, John Q.; Shaw, Leslie M.; Weiner, Michael W. und Haass, Christian
(2019):
Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer's disease.
In: Science Translational Medicine, Bd. 11, Nr. 507, eaav6221
[PDF, 786kB]
ORCID: https://orcid.org/0000-0002-0654-387X; Trojanowski, John Q.; Shaw, Leslie M.; Weiner, Michael W. und Haass, Christian
(2019):
Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer's disease.
In: Science Translational Medicine, Bd. 11, Nr. 507, eaav6221
[PDF, 786kB]
Suarez-Calvet, Marc; Capell, Anja; Caballero, Miguel Angel Araque; Morenas-Rodriguez, Estrella; Fellerer, Katrin; Franzmeier, Nicolai; Kleinberger, Gernot; Eren, Erden; Deming, Yuetiva; Piccio, Laura; Karch, Celeste M.; Cruchaga, Carlos; Paumier, Katrina; Bateman, Randall J.; Fagan, Anne M.; Morris, John C.; Levin, Johannes; Danek, Adrian; Jucker, Mathias; Masters, Colin L.; Rossor, Martin N.; Ringman, John M.; Shaw, Leslie M.; Trojanowski, John Q.; Weiner, Michael; Ewers, Michael und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2018):
CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline.
In: EMBO Molecular Medicine, Bd. 10, Nr. 12, e9712
ORCID: https://orcid.org/0000-0002-4869-1627
(2018):
CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline.
In: EMBO Molecular Medicine, Bd. 10, Nr. 12, e9712
Caballero, Miguel Angel Araque; Suarez-Calvet, Marc; Duering, Marco; Franzmeier, Nicolai; Benzinger, Tammie; Fagan, Anne M.; Bateman, Randall J.; Jack, Clifford R.; Levin, Johannes; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Jucker, Mathias; Karch, Celeste; Masters, Colin L.; Morris, John C.; Weiner, Michael; Rossor, Martin; Fox, Nick C.; Lee, Jae-Hong; Salloway, Stephen; Danek, Adrian; Goate, Alison; Yakushev, Igor; Hassenstab, Jason; Schofield, Peter R.; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627 und Ewers, Michael
(2018):
White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer’s disease.
In: Brain, Bd. 141: S. 3065-3080
ORCID: https://orcid.org/0000-0002-0654-387X; Jucker, Mathias; Karch, Celeste; Masters, Colin L.; Morris, John C.; Weiner, Michael; Rossor, Martin; Fox, Nick C.; Lee, Jae-Hong; Salloway, Stephen; Danek, Adrian; Goate, Alison; Yakushev, Igor; Hassenstab, Jason; Schofield, Peter R.; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627 und Ewers, Michael
(2018):
White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer’s disease.
In: Brain, Bd. 141: S. 3065-3080
Franzmeier, Nicolai; Düzel, Emrah; Jessen, Frank; Bürger, Katharina; Levin, Johannes; Duering, Marco; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Suarez-Calvet, Marc; Fagan, Anne M.; Paumier, Katrina; Benzinger, Tammie; Masters, Colin L.; Morris, John C.; Perneczky, Robert; Janowitz, Daniel; Catak, Cihan; Wolfsgruber, Steffen; Wagner, Michael; Teipel, Stefan; Kilimann, Ingo; Ramirez, Alfredo; Rossor, Martin; Jucker, Mathias; Chhatwal, Jasmeer; Spottke, Annika; Böcker, Henning; Brosseron, Frederic; Falkai, Peter ORCID: https://orcid.org/0000-0003-2873-8667; Fliessbach, Klaus; Heneka, Michael T.; Laske, Christoph; Nestor, Peter; Peters, Oliver; Fuentes, Manuel; Menne, Felix; Priller, Josef; Spruth, Eike J.; Franke, Christiana; Schneider, Anja; Kofler, Barbara; Westerteicher, Christine; Speck, Oliver; Wiltfang, Jens; Bartels, Claudia; Caballero, Miguel Angel Araque; Metzger, Coraline; Bittner, Daniel; Weiner, Michael; Lee, Jae-Hong; Salloway, Stephen; Danek, Adrian; Goate, Alison; Schofield, Peter R.; Bateman, Randall J. und Ewers, Michael
(2018):
Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer’s disease.
In: Brain, Bd. 141: S. 1186-1200
ORCID: https://orcid.org/0000-0002-0654-387X; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Suarez-Calvet, Marc; Fagan, Anne M.; Paumier, Katrina; Benzinger, Tammie; Masters, Colin L.; Morris, John C.; Perneczky, Robert; Janowitz, Daniel; Catak, Cihan; Wolfsgruber, Steffen; Wagner, Michael; Teipel, Stefan; Kilimann, Ingo; Ramirez, Alfredo; Rossor, Martin; Jucker, Mathias; Chhatwal, Jasmeer; Spottke, Annika; Böcker, Henning; Brosseron, Frederic; Falkai, Peter ORCID: https://orcid.org/0000-0003-2873-8667; Fliessbach, Klaus; Heneka, Michael T.; Laske, Christoph; Nestor, Peter; Peters, Oliver; Fuentes, Manuel; Menne, Felix; Priller, Josef; Spruth, Eike J.; Franke, Christiana; Schneider, Anja; Kofler, Barbara; Westerteicher, Christine; Speck, Oliver; Wiltfang, Jens; Bartels, Claudia; Caballero, Miguel Angel Araque; Metzger, Coraline; Bittner, Daniel; Weiner, Michael; Lee, Jae-Hong; Salloway, Stephen; Danek, Adrian; Goate, Alison; Schofield, Peter R.; Bateman, Randall J. und Ewers, Michael
(2018):
Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer’s disease.
In: Brain, Bd. 141: S. 1186-1200
Brendel, Matthias; Kleinberger, Gernot; Probst, Federico; Jaworska, Anna; Overhoff, Felix; Blume, Tanja; Albert, Nathalie L.; Carlsen, Janette; Lindner, Simon; Gildehaus, Franz Josef; Ozmen, Laurence; Suarez-Calvet, Marc; Bartenstein, Peter; Baumann, Karlheinz; Ewers, Michael; Herms, Jochen; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627 und Rominger, Axel
(Januar 2017):
Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis.
In: Frontiers in aging neuroscience, Bd. 9, 8
[PDF, 2MB]
ORCID: https://orcid.org/0000-0002-4869-1627 und Rominger, Axel
(Januar 2017):
Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis.
In: Frontiers in aging neuroscience, Bd. 9, 8
[PDF, 2MB]
Kleinberger, Gernot; Brendel, Matthias; Mracsko, Eva; Wefers, Benedikt; Groeneweg, Linda; Xiang, Xianyuan; Focke, Carola; Deußing, Maximilian; Suarez-Calvet, Marc; Mazaheri, Fargol; Parhizkar, Samira; Pettkus, Nadine; Wurst, Wolfgang; Feederle, Regina; Bartenstein, Peter; Mueggler, Thomas; Arzberger, Thomas; Knuesel, Irene; Rominger, Axel und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2017):
The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.
In: Embo Journal, Bd. 36, Nr. 13: S. 1837-1853
ORCID: https://orcid.org/0000-0002-4869-1627
(2017):
The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.
In: Embo Journal, Bd. 36, Nr. 13: S. 1837-1853
Suarez-Calvet, Marc; Kleinberger, Gernot; Araque Caballero, Miguel Angel; Brendel, Matthias; Rominger, Axel; Alcolea, Daniel; Fortea, Juan; Lleo, Alberto; Blesa, Rafael; Gispert, Juan Domingo; Sanchez-Valle, Raquel; Antonell, Anna; Rami, Lorena; Molinuevo, Jose L.; Brosseron, Frederic; Traschutz, Andreas; Heneka, Michael T.; Struyfs, Hanne; Engelborghs, Sebastiaan; Sleegers, Kristel; Broeckhoven, Christine van; Zetterberg, Henrik; Nellgard, Bengt; Blennow, Kaj; Crispin, Alexander; Ewers, Michael und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2016):
sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers.
In: EMBO Molecular Medicine, Bd. 8, Nr. 5: S. 466-476
ORCID: https://orcid.org/0000-0002-4869-1627
(2016):
sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers.
In: EMBO Molecular Medicine, Bd. 8, Nr. 5: S. 466-476