Anzahl der Publikationen: 108
2024
Vinnakota, Janaki Manoja; Biavasco, Francesca; Schwabenland, Marius ORCID: https://orcid.org/0000-0003-2205-5427; Chhatbar, Chintan; Adams, Rachael C.; Erny, Daniel ORCID: https://orcid.org/0000-0001-6000-8838; Duquesne, Sandra; El Khawanky, Nadia; Schmidt, Dominik ORCID: https://orcid.org/0000-0002-7744-1248; Fetsch, Viktor; Zähringer, Alexander; Salié, Henrike ORCID: https://orcid.org/0000-0002-2993-3782; Athanassopoulos, Dimitrios; Braun, Lukas M. ORCID: https://orcid.org/0000-0003-0770-4994; Javorniczky, Nora R.; Ho, Jenny N. H. G.; Kierdorf, Katrin ORCID: https://orcid.org/0000-0002-9272-4780; Marks, Reinhard; Wäsch, Ralph ORCID: https://orcid.org/0000-0002-0813-3444; Simonetta, Federico; Andrieux, Geoffroy ORCID: https://orcid.org/0000-0002-5389-9481; Pfeifer, Dietmar; Monaco, Gianni; Capitini, Christian ORCID: https://orcid.org/0000-0002-2276-6731; Fry, Terry J. ORCID: https://orcid.org/0000-0001-8044-5226; Blank, Thomas ORCID: https://orcid.org/0000-0002-3969-405X; Blazar, Bruce R. ORCID: https://orcid.org/0000-0002-9608-9841; Wagner, Eva ORCID: https://orcid.org/0000-0002-0728-2253; Theobald, Matthias; Sommer, Clemens; Stelljes, Matthias; Reicherts, Christian; Jeibmann, Astrid; Schittenhelm, Jens; Monoranu, Camelia-Maria; Rosenwald, Andreas; Kortüm, Martin ORCID: https://orcid.org/0000-0002-7011-0286; Rasche, Leo ORCID: https://orcid.org/0000-0002-9536-9649; Einsele, Hermann ORCID: https://orcid.org/0000-0002-7680-0819; Meyer, Philipp T.; Brumberg, Joachim; Völkl, Simon; Mackensen, Andreas; Coras, Roland; Bergwelt-Baildon, Michael von ORCID: https://orcid.org/0000-0002-1952-052X; Albert, Nathalie L.; Bartos, Laura M.; Brendel, Matthias ORCID: https://orcid.org/0000-0002-9247-2843; Holzgreve, Adrien ORCID: https://orcid.org/0000-0002-9566-8438; Mack, Matthias ORCID: https://orcid.org/0000-0002-3157-7262; Boerries, Melanie ORCID: https://orcid.org/0000-0002-3670-0602; Mackall, Crystal L. ORCID: https://orcid.org/0000-0001-6323-4304; Duyster, Justus; Henneke, Philipp; Priller, Josef; Köhler, Natalie ORCID: https://orcid.org/0000-0002-7502-0431; Strübing, Felix ORCID: https://orcid.org/0000-0002-9436-6294; Bengsch, Bertram ORCID: https://orcid.org/0000-0003-2552-740X; Ruella, Marco ORCID: https://orcid.org/0000-0003-4301-5811; Subklewe, Marion ORCID: https://orcid.org/0000-0001-9154-9469; Baumgarten, Louisa von ORCID: https://orcid.org/0000-0002-6634-0927; Gill, Saar; Prinz, Marco ORCID: https://orcid.org/0000-0002-0349-1955 und Zeiser, Robert ORCID: https://orcid.org/0000-0001-6565-3393
(2024):
Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome.
In: Nature Cancer [Forthcoming]
Hänel, Gerulf ORCID: https://orcid.org/0000-0003-4685-6499; Schöne, Anne; Neumann, Anne-Sophie; Nixdorf, Daniel ORCID: https://orcid.org/0000-0003-1612-9952; Philipp, Nora ORCID: https://orcid.org/0000-0002-3918-7795; Sponheimer, Monika; Leutbecher, Alexandra; Emhardt, Alica-Joana; Magno, Giulia; Bücklein, Veit ORCID: https://orcid.org/0000-0001-7391-7280; Eckmann, Jan; Dunshee, Diana; Kramar, Vesna; Korfi, Koorosh; Colombetti, Sara; Umaña, Pablo ORCID: https://orcid.org/0000-0001-8206-2771; Klein, Christian ORCID: https://orcid.org/0000-0001-7594-7280 und Subklewe, Marion ORCID: https://orcid.org/0000-0001-9154-9469
(2024):
Combining venetoclax and azacytidine with T-cell bispecific antibodies for treatment of acute myeloid leukemia: a preclinical assessment.
In: Leukemia, Nr. 38: S. 348-402
[PDF, 1MB]
2023
Bücklein, Veit; Perez, Ariel; Rejeski, Kai; Iacoboni, Gloria; Jurinovic, Vindi; Holtick, Udo; Penack, Olaf; Kharboutli, Soraya; Blumenberg, Viktoria; Ackermann, Josephine; Frölich, Lisa; Johnson, Grace; Patel, Kedar; Arciola, Brian; Mhaskar, Rahul; Wood, Anthony; Schmidt, Christian; Albanyan, Omar; Gödel, Philipp; Hoster, Eva ORCID: https://orcid.org/0000-0002-0749-1389; Bullinger, Lars; Mackensen, Andreas; Locke, Frederick; Bergwelt-Baildon, Michael von ORCID: https://orcid.org/0000-0002-1952-052X; Barba, Pere; Subklewe, Marion und Jain, Michael D.
(2023):
Inferior Outcomes of EU Versus US Patients Treated With CD19 CAR-T for Relapsed/Refractory Large B-cell Lymphoma: Association With Differences in Tumor Burden, Systemic Inflammation, Bridging Therapy Utilization, and CAR-T Product Use.
In: HemaSphere, Bd. 7, Nr. 8, e907
Blumenberg, Viktoria ORCID: https://orcid.org/0000-0003-1379-0876; Galina, Busch; Baumann, Stephan ORCID: https://orcid.org/0009-0001-2804-2072; Jitschin, Regina; Iacoboni, Gloria ORCID: https://orcid.org/0000-0003-0805-9288; Hoster, Eva ORCID: https://orcid.org/0000-0002-0749-1389; Gallur, Laura ORCID: https://orcid.org/0000-0001-6293-9281; Iraola-Truchuelo, Josu ORCID: https://orcid.org/0000-0002-9909-3715; Winkelmann, Michael; Hellwig, Konstantin ORCID: https://orcid.org/0000-0001-9001-2176; Schmidt, Christian; Frölich, Lisa; Tast, Benjamin; Hildebrand, Friederike; Rejeski, Kai ORCID: https://orcid.org/0000-0003-3905-0251; Dekorsy, Franziska J.; Schmidkonz, Christian; Bäuerle, Tobias; Kunz, Wolfgang G. ORCID: https://orcid.org/0000-0002-5021-1952; Mougiakakos, Dimitrios ORCID: https://orcid.org/0000-0002-2817-6660; Müller, Fabian ORCID: https://orcid.org/0000-0001-5487-5839; Bergwelt-Baildon, Michael von ORCID: https://orcid.org/0000-0002-1952-052X; Barba, Pere; Bücklein, Veit L. ORCID: https://orcid.org/0000-0001-7391-7280; Mackensen, Andreas ORCID: https://orcid.org/0000-0002-0685-4483; Völkl, Simon und Subklewe, Marion ORCID: https://orcid.org/0000-0001-9154-9469
(2023):
Early quantification of anti-CD19 CAR T-cells by flow cytometry predicts response in R/R DLBCL.
In: Blood Advances, Bd. 7, Nr. 22: S. 6844-6849
[PDF, 498kB]
Kuhl, Niklas ORCID: https://orcid.org/0000-0003-4970-4677; Linder, Andreas ORCID: https://orcid.org/0000-0002-0623-5105; Philipp, Nora ORCID: https://orcid.org/0000-0002-3918-7795; Nixdorf, Daniel ORCID: https://orcid.org/0000-0003-1612-9952; Fischer, Hannah ORCID: https://orcid.org/0000-0003-0540-1930; Veth, Simon; Kuut, Gunnar; Xu, Teng Teng ORCID: https://orcid.org/0000-0001-9129-913X; Theurich, Sebastian ORCID: https://orcid.org/0000-0001-5706-8258; Carell, Thomas; Subklewe, Marion ORCID: https://orcid.org/0000-0001-9154-9469 und Hornung, Veit ORCID: https://orcid.org/0000-0002-4150-194X
(2023):
STING agonism turns human T cells into interferon‐producing cells but impedes their functionality.
In: EMBO reports, Bd. 24, Nr. 3
[PDF, 1MB]
Stock, Sophia ORCID: https://orcid.org/0000-0002-5072-5013; Klüver, Anna‐Kristina; Fertig, Luisa; Menkhoff, Vivien D.; Subklewe, Marion; Endres, Stefan und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2023):
Mechanisms and strategies for safe chimeric antigen receptor T‐cell activity control.
In: International Journal of Cancer, Bd. 153, Nr. 10: S. 1706-1725
[PDF, 4MB]
Rejeski, Kai ORCID: https://orcid.org/0000-0003-3905-0251; Wang, Yucai ORCID: https://orcid.org/0000-0002-1576-8341; Albanyan, Omar; Munoz, Javier; Sesques, Pierre ORCID: https://orcid.org/0000-0001-8264-822X; Iacoboni, Gloria; Lopez‐Corral, Lucia; Ries, Isabelle; Bücklein, Veit L.; Mohty, Razan; Dreyling, Martin; Baluch, Aliyah; Shah, Bijal ORCID: https://orcid.org/0000-0003-4328-6021; Locke, Frederick L.; Hess, Georg; Barba, Pere; Bachy, Emmanuel; Lin, Yi; Subklewe, Marion ORCID: https://orcid.org/0000-0001-9154-9469 und Jain, Michael D. ORCID: https://orcid.org/0000-0002-7789-1257
(2023):
The CAR‐HEMATOTOX score identifies patients at high risk for hematological toxicity, infectious complications, and poor treatment outcomes following brexucabtagene autoleucel for relapsed or refractory MCL.
In: American Journal of Hematology, Bd. 98, Nr. 11: S. 1699-1710
[PDF, 2MB]
Marcinek, Anetta; Brauchle, Bettina; Rohrbacher, Lisa; Hänel, Gerulf; Philipp, Nora; Märkl, Florian; Strzalkowski, Thaddäus; Lacher, Sonja M.; Udiljak, Dragica; Spiekermann, Karsten ORCID: https://orcid.org/0000-0002-5139-4957; Theurich, Sebastian; Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673; Kischel, Roman; James, John R.; Bücklein, Veit L. und Subklewe, Marion ORCID: https://orcid.org/0000-0001-9154-9469
(2023):
CD33 BiTE® molecule-mediated immune synapse formation and subsequent T-cell activation is determined by the expression profile of activating and inhibitory checkpoint molecules on AML cells.
In: Cancer Immunology, Immunotherapy, Bd. 72, Nr. 7: S. 2499-2512
[PDF, 1MB]
Weiss, L.; Dorman, K.; Boukovala, M.; Schwinghammer, F.; Jordan, P.; Fey, T.; Hasselmann, K.; Subklewe, Marion; Bücklein, V.; Bargou, R.; Goebeler, M.; Sayehli, C.; Spoerl, S.; Lüke, F.; Heudobler, D.; Claus, R.; Luettichau, I. von; Lorenzen, S.; Lange, S.; Westphalen, C. B.; Bergwelt-Baildon, Michael von ORCID: https://orcid.org/0000-0002-1952-052X; Heinemann, V. und Gießen-Jung, Clemens ORCID: https://orcid.org/0000-0003-0537-1727
(2023):
Early clinical trial unit tumor board: a real-world experience in a national cancer network.
In: Journal of Cancer Research and Clinical Oncology, Bd. 149, Nr. 14: S. 13383-13390
[PDF, 889kB]
Ruzicka, Michael ORCID: https://orcid.org/0000-0002-2451-1070; Ibarra Fonseca, Gerardo Jesus; Sachenbacher, Simone; Heimkes, Fides; Grosse-Wentrup, Fabienne; Wunderlich, Nora; Benesch, Christopher; Pernpruner, Anna; Valdinoci, Elisabeth; Rueb, Mike ORCID: https://orcid.org/0000-0002-2057-383X; Uebleis, Aline Olivia; Karch, Susanne ORCID: https://orcid.org/0000-0002-1542-1110; Bogner, Johannes R. ORCID: https://orcid.org/0000-0001-8628-1533; Mayerle, Julia ORCID: https://orcid.org/0000-0002-3666-6459; Bergwelt-Baildon, Michael von ORCID: https://orcid.org/0000-0002-1952-052X; Subklewe, Marion ORCID: https://orcid.org/0000-0001-9154-9469; Heindl, Bernhard; Stubbe, Hans Christian ORCID: https://orcid.org/0000-0002-7873-996X und Adorjan, Kristina ORCID: https://orcid.org/0000-0001-7501-9556
(2023):
Substantial differences in perception of disease severity between post COVID-19 patients, internists, and psychiatrists or psychologists: the Health Perception Gap and its clinical implications.
In: European Archives of Psychiatry and Clinical Neuroscience [Forthcoming]
Nixdorf, D. ORCID: https://orcid.org/0000-0003-1612-9952; Sponheimer, M.; Berghammer, D.; Engert, F. ORCID: https://orcid.org/0000-0002-2795-2402; Bader, U.; Philipp, N. ORCID: https://orcid.org/0000-0002-3918-7795; Kazerani, M. ORCID: https://orcid.org/0000-0002-5803-4807; Straub, T.; Rohrbacher, L.; Wange, L. ORCID: https://orcid.org/0000-0002-3275-9156; Dapa, S.; Atar, D.; Seitz, C. M.; Brandstetter, K.; Linder, A.; Bergwelt-Baildon, Michael von ORCID: https://orcid.org/0000-0002-1952-052X; Leonhardt, H. ORCID: https://orcid.org/0000-0002-5086-6449; Mittelstaet, J.; Kaiser, A.; Bücklein, V. ORCID: https://orcid.org/0000-0001-7391-7280 und Subklewe, Marion ORCID: https://orcid.org/0000-0001-9154-9469
(2023):
Adapter CAR T cells to counteract T-cell exhaustion and enable flexible targeting in AML.
In: Leukemia, Bd. 37, Nr. 6: S. 1298-1310
[PDF, 3MB]
Gottschlich, Adrian; Thomas, Moritz; Gruenmeier, Ruth; Lesch, Stefanie; Rohrbacher, Lisa; Igl, Veronika; Briukhovetska, Daria; Benmebarek, Mohamed-Reda; Vick, Binje; Dede, Sertac; Mueller, Katharina; Xu, Tao; Dhoqina, Dario; Maerkl, Florian; Robinson, Sophie; Sendelhofert, Andrea; Schulz, Heiko; Umut, Oeykue; Kavaka, Vladyslav; Tsiverioti, Christina Angeliki; Carlini, Emanuele; Nandi, Sayantan; Strzalkowski, Thaddaeus; Lorenzini, Theo; Stock, Sophia; Mueller, Philipp Jie; Doerr, Janina; Seifert, Matthias; Cadilha, Bruno L.; Brabenec, Ruben; Roeder, Natalie; Rataj, Felicitas; Nueesch, Manuel; Modemann, Franziska; Wellbrock, Jasmin; Fiedler, Walter; Kellner, Christian; Beltran, Eduardo; Herold, Tobias; Paquet, Dominik; Jeremias, Irmela; von Baumgarten, Louisa; Endres, Stefan; Subklewe, Marion; Marr, Carsten und Kobold, Sebastian
(2023):
Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia.
In: Nature Biotechnology, Bd. 41, Nr. 11:
1618-+
[PDF, 7MB]
2022
Khatamzas, Elham; Antwerpen, Markus H.; Rehn, Alexandra; Graf, Alexander; Hellmuth, Johannes Christian; Hollaus, Alexandra; Mohr, Anne-Wiebe; Gaitzsch, Erik; Weiglein, Tobias; Georgi, Enrico; Scherer, Clemens; Stecher, Stephanie-Susanne; Gruetzner, Stefanie; Blum, Helmut; Krebs, Stefan; Reischer, Anna; Leutbecher, Alexandra; Subklewe, Marion; Dick, Andrea; Zange, Sabine; Girl, Philipp; Müller, Katharina; Weigert, Oliver; Hopfner, Karl-Peter; Stemmler, Hans-Joachim; Bergwelt-Baildon, Michael von; Keppler, Oliver T.; Wölfel, Roman; Muenchhoff, Maximilian und Moosmann, Andreas
(23. September 2022):
Accumulation of mutations in antibody and CD8 T cell epitopes in a B cell depleted lymphoma patient with chronic SARS-CoV-2 infection.
In: Nature Communications, Bd. 13
[PDF, 3MB]
Winkelmann, Michael; Bücklein, Veit L.; Blumenberg, Viktoria; Rejeski, Kai; Ruzicka, Michael; Unterrainer, Marcus; Schmidt, Christian; Dekorsy, Franziska J.; Bartenstein, Peter; Ricke, Jens; von Bergwelt-Baildon, Michael; Subklewe, Marion und Kunz, Wolfgang G.
(8. September 2022):
Lymphoma tumor burden before chimeric antigen receptor T-Cell treatment: RECIL vs. Lugano vs. metabolic tumor assessment.
In: Frontiers in Oncology, Bd. 12
[PDF, 2MB]
Köhnke, Thomas; Liu, Xilong; Haubner, Sascha; Bücklein, Veit; Hänel, Gerulf; Krupka, Christina; Solis-Mezarino, Victor; Herzog, Franz und Subklewe, Marion
(10. Juni 2022):
Integrated multiomic approach for identification of novel immunotherapeutic targets in AML.
In: Biomarker Research, Bd. 10
[PDF, 5MB]
Rejeski, Kai ORCID: https://orcid.org/0000-0003-3905-0251; Perez, Ariel; Iacoboni, Gloria; Penack, Olaf; Bücklein, Veit; Jentzsch, Liv; Mougiakakos, Dimitrios; Johnson, Grace; Arciola, Brian; Carpio, Cecilia; Blumenberg, Viktoria; Hoster, Eva ORCID: https://orcid.org/0000-0002-0749-1389; Bullinger, Lars; Locke, Frederick L; Bergwelt-Baildon, Michael von ORCID: https://orcid.org/0000-0002-1952-052X; Mackensen, Andreas; Bethge, Wolfgang; Barba, Pere; Jain, Michael D ORCID: https://orcid.org/0000-0002-7789-1257 und Subklewe, Marion
(2022):
The CAR-HEMATOTOX risk-stratifies patients for severe infections and disease progression after CD19 CAR-T in R/R LBCL.
In: Journal for ImmunoTherapy of Cancer, Bd. 10, e004475
[PDF, 5MB]
Ruzicka, Michael ORCID: https://orcid.org/0000-0002-2451-1070; Wurm, Sonja ORCID: https://orcid.org/0000-0002-7540-737X; Lindner, Lars H. ORCID: https://orcid.org/0000-0003-3708-8264; Dreyling, Martin ORCID: https://orcid.org/0000-0002-0358-5249; Bergwelt-Baildon, Michael von ORCID: https://orcid.org/0000-0002-1952-052X; Boeck, Stefan ORCID: https://orcid.org/0000-0002-1922-2127; Giessen-Jung, Clemens; Milani, Valeria; Stemmler, Joachim H. ORCID: https://orcid.org/0000-0001-8751-8555; Subklewe, Marion ORCID: https://orcid.org/0000-0001-9154-9469; Weigert, Oliver ORCID: https://orcid.org/0000-0002-0987-7373 und Spiekermann, Karsten ORCID: https://orcid.org/0000-0002-5139-4957
(2022):
Treatment, outcome and re-vaccination of patients with SARS-CoV-2 vaccine-associated immune thrombocytopenia.
In: Infection, Bd. 51, Nr. 1: S. 231-238
[PDF, 723kB]
Stock, Sophia ORCID: https://orcid.org/0000-0002-5072-5013; Benmebarek, Mohamed-Reda ORCID: https://orcid.org/0000-0002-1201-7067; Kluever, Anna-Kristina ORCID: https://orcid.org/0000-0001-6246-6082; Darowski, Diana ORCID: https://orcid.org/0000-0002-8778-7920; Jost, Christian ORCID: https://orcid.org/0000-0002-4169-5879; Stubenrauch, Kay-Gunnar; Benz, Joerg; Freimoser-Grundschober, Anne ORCID: https://orcid.org/0000-0001-5715-3639; Moessner, Ekkehard; Umana, Pablo; Subklewe, Marion ORCID: https://orcid.org/0000-0001-9154-9469; Endres, Stefan ORCID: https://orcid.org/0000-0002-4703-537X; Klein, Christian ORCID: https://orcid.org/0000-0001-7594-7280 und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2022):
Chimeric antigen receptor T cells engineered to recognize the P329G-mutated Fc part of effector-silenced tumor antigen-targeting human IgG1 antibodies enable modular targeting of solid tumors.
In: Journal for ImmunoTherapy of Cancer, Bd. 10, Nr. 7, e005054
[PDF, 17MB]
Winkelmann, Michael; Blumenberg, Viktoria; Rejeski, Kai; Buecklein, Veit L.; Ruzicka, Michael; Unterrainer, Marcus; Schmidt, Christian; Dekorsy, Franziska J.; Bartenstein, Peter; Ricke, Jens; Bergwelt-Baildon, Michael von; Subklewe, Marion und Kunz, Wolfgang G.
(2022):
Prognostic value of the International Metabolic Prognostic Index for lymphoma patients receiving chimeric antigen receptor T-cell therapy.
In: European Journal of Nuclear Medicine and Molecular Imaging, Bd. 50: S. 1406-1413
Fahrmann, Johannes F.; Saini, Neeraj Y.; Chia-Chi, Chang; Irajizad, Ehsan; Strati, Paolo; Nair, Ranjit; Fayad, Luis E.; Ahmed, Sairah; Lee, Hun Ju; Iyer, Swaminathan; Steiner, Raphael; Vykoukal, Jody; Wu, Ranran; Dennison, Jennifer B.; Nastoupil, Loretta; Jain, Preetesh; Wang, Michael; Green, Michael; Westin, Jason; Blumenberg, Viktoria; Davila, Marco; Champlin, Richard; Shpall, Elizabeth J.; Kebriaei, Partow; Flowers, Christopher R.; Jain, Michael; Jenq, Robert; Stein-Thoeringer, Christoph K.; Subklewe, Marion; Neelapu, Sattva S. und Hanash, Sam
(2022):
A polyamine-centric, blood-based metabolite panel predictive of poor response to CAR-T cell therapy in B cell lymphoma.
In: Cell Reports Medicine, Bd. 3, Nr. 11, 100720
Tettero, Jesse M.; Freeman, Sylvie; Buecklein, Veit; Venditti, Adriano; Maurillo, Luca; Kern, Wolfgang; Walter, Roland B.; Wood, Brent L.; Roumier, Christophe; Philippe, Jan; Denys, Barbara; Jorgensen, Jeffrey L.; Bene, Marie C.; Lacombe, Francis; Plesa, Adriana; Guzman, Monica L.; Wierzbowska, Agnieszka; Czyz, Anna; Ngai, Lok Lam; Schwarzer, Adrian; Bachas, Costa; Cloos, Jacqueline; Subklewe, Marion; Fuering-Buske, Michaela und Buccisano, Francesco
(2022):
Technical Aspects of Flow Cytometry-based Measurable Residual Disease Quantification in Acute Myeloid Leukemia: Experience of the European LeukemiaNet MRD Working Party.
In: Hemasphere, Bd. 6, Nr. 1, e676
Philipp, Nora; Kazerani, Maryam; Nicholls, Alyssa; Vick, Binje; Wulf, Jan; Straub, Tobias; Scheurer, Michaela; Muth, Amelie; Hänel, Gerulf; Nixdorf, Daniel; Sponheimer, Monika; Ohlmeyer, Malte; Lacher, Sonja M.; Brauchle, Bettina; Marcinek, Anetta; Rohrbacher, Lisa; Leutbecher, Alexandra; Rejeski, Kai; Weigert, Oliver; Bergwelt-Baildon, Michael von; Theurich, Sebastian; Kischel, Roman; Jeremias, Irmela; Bücklein, Veit und Subklewe, Marion
(2022):
T-cell exhaustion induced by continuous bispecific molecule exposure is ameliorated by treatment-free intervals.
In: Blood, Bd. 140, Nr. 10: S. 1104-1118
Schoeberl, Florian; Tiedt, Steffen; Schmitt, Anita; Blumenberg, Viktoria; Karschnia, Philipp; Burbano, Vanessa Granja; Bucklein, Veit L.; Rejeski, Kai; Schmidt, Christian; Busch, Galina; Bergwelt-Baildon, Michael von; Tonn, Jörg-Christian; Schmitt, Michael; Subklewe, Marion und Baumgarten, Louisa von
(2022):
Neurofilament light chain serum levels correlate with the severity of neurotoxicity after CAR T-cell treatment.
In: Blood Advances, Bd. 6, Nr. 10: S. 3022-3026
Shah, Bijal D.; Ghobadi, Armin; Oluwole, Olalekan O.; Logan, Aaron C.; Boissel, Nicolas; Cassaday, Ryan D.; Leguay, Thibaut; Bishop, Michael R.; Topp, Max S.; Tzachanis, Dimitrios; O'Dwyer, Kristen M.; Arellano, Martha L.; Lin, Yi; Baer, Maria R.; Schiller, Gary J.; Park, Jae H.; Subklewe, Marion; Abedi, Mehrdad; Minnema, Monique C.; Wierda, William G.; DeAngelo, Daniel J.; Stiff, Patrick; Jeyakumar, Deepa; Dong, Jinghui; Adhikary, Sabina; Zhou, Lang; Schuberth, Petra C.; Faghmous, Imi; Masouleh, Behzad Kharabi und Houot, Roch
(2022):
Two-year follow-up of KTE-X19 in patients with relapsed or refractory adult B-cell acute lymphoblastic leukemia in ZUMA-3 and its contextualization with SCHOLAR-3, an external historical control study.
In: Journal of Hematology & Oncology, Bd. 15, Nr. 1, 170
Santos, David M. Cordas dos; Rejeski, Kai; Winkelmann, Michael; Liu, Lian; Trinkner, Paul; Guenther, Sophie; Buecklein, Veit L.; Blumenberg, Viktoria; Schmidt, Christian; Kunz, Wolfgang G.; Bergwelt-Baildon, Michael von; Theurich, Sebastian und Subklewe, Marion
(2022):
Increased visceral fat distribution and body composition impact cytokine release syndrome onset and severity after CD19 chimeric antigen receptor T-cell therapy in advanced B-cell malignancies.
In: Haematologica, Bd. 107, Nr. 9: S. 2096-2107
2021
Benmebarek, Mohamed-Reda; Cadilha, Bruno L.; Herrmann, Monika; Lesch, Stefanie; Schmitt, Saskia; Stoiber, Stefan; Darwich, Abbass; Augsberger, Christian; Brauchle, Bettina; Rohrbacher, Lisa; Oner, Arman; Seifert, Matthias; Schwerdtfeger, Melanie; Gottschlich, Adrian; Rataj, Felicitas; Fenn, Nadja C.; Klein, Christian ORCID: https://orcid.org/0000-0001-7594-7280; Subklewe, Marion; Endres, Stefan; Hopfner, Karl-Peter ORCID: https://orcid.org/0000-0002-4528-8357 und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2021):
A modular and controllable T cell therapy platform for acute myeloid leukemia.
In: Leukemia, Bd. 35: S. 2243-2257
[PDF, 5MB]
Rejeski, Kai; Kunz, Wolfgang G.; Rudelius, Martina; Bücklein, Veit; Blumenberg, Viktoria; Schmidt, Christian; Karschnia, Philipp; Schöberl, Florian; Dimitriadis, Konstantin; Baumgarten, Louisa von; Stemmler, Joachim; Weigert, Oliver; Dreyling, Martin; Bergwelt-Baildon, Michael von und Subklewe, Marion
(2021):
Severe Candida glabrata pancolitis and fatal Aspergillus fumigatus pulmonary infection in the setting of bone marrow aplasia after CD19-directed CAR T-cell therapy - a case report.
In: BMC infectious diseases, Bd. 21, Nr. 1, 121
[PDF, 7MB]
Tahk, Siret; Vick, Binje; Hiller, Björn; Schmitt, Saskia; Marcinek, Anetta; Perini, Enrico D.; Leutbecher, Alexandra; Augsberger, Christian; Reischer, Anna; Tast, Benjamin; Humpe, Andreas; Jeremias, Irmela; Subklewe, Marion; Fenn, Nadja C. und Hopfner, Karl-Peter ORCID: https://orcid.org/0000-0002-4528-8357
(2021):
SIRPα-αCD123 fusion antibodies targeting CD123 in conjunction with CD47 blockade enhance the clearance of AML-initiating cells.
In: Journal of hematology & oncology, Bd. 14, 155
[PDF, 3MB]
Augsberger, Christian; Hanel, Gerulf; Xu, Wei; Pulko, Vesna; Hanisch, Lydia Jasmin; Augustin, Angelique; Challier, John; Hunt, Katharina; Vick, Binje; Rovatti, Pier Eduardo; Krupka, Christina; Rothe, Maurine; Schonle, Anne; Sam, Johannes; Lezan, Emmanuelle; Ducret, Axel; Ortiz-Franyuti, Daniela; Walz, Antje-Christine; Benz, Jorg; Bujotzek, Alexander; Lichtenegger, Felix S.; Gassner, Christian; Carpy, Alejandro; Lyamichev, Victor; Patel, Jigar; Konstandin, Nikola; Tunger, Antje; Schmitz, Marc; Bergwelt-Baildon, Michael von; Spiekermann, Karsten; Vago, Luca; Jeremias, Irmela; Marrer-Berger, Estelle; Umana, Pablo; Klein, Christian und Subklewe, Marion
(2021):
Targeting intracellular WT1 in AML with a novel RMF-peptide-MHC-specific T-cell bispecific antibody.
In: Blood, Bd. 138, Nr. 25: S. 2655-2669
Benmebarek, Mohamed-Reda; Cadilha, Bruno L.; Herrmann, Monika; Lesch, Stefanie; Schmitt, Saskia; Stoiber, Stefan; Darwich, Abbass; Augsberger, Christian; Brauchle, Bettina; Rohrbacher, Lisa; Oner, Arman; Seifert, Matthias; Schwerdtfeger, Melanie; Gottschlich, Adrian; Rataj, Felicitas; Fenn, Nadja C.; Klein, Christian; Subklewe, Marion; Endres, Stefan; Hopfner, Karl-Peter und Kobold, Sebastian
(2021):
A modular and controllable T cell therapy platform for acute myeloid leukemia.
In: Leukemia, Bd. 35, Nr. 8: S. 2243-2257
Cadilha, Bruno L.; Benmebarek, Mohamed-Reda; Dorman, Klara; Oner, Arman; Lorenzini, Theo; Obeck, Hannah; Vaenttinen, Mira; Di Pilato, Mauro; Pruessmann, Jasper N.; Stoiber, Stefan; Duc, Huynh; Maerkl, Florian; Seifert, Matthias; Manske, Katrin; Suarez-Gosalvez, Javier; Zeng, Yi; Lesch, Stefanie; Karches, Clara H.; Heise, Constanze; Gottschlich, Adrian; Thomas, Moritz; Marr, Carsten; Zhang, Jin; Pandey, Dharmendra; Feuchtinger, Tobias; Subklewe, Marion; Mempel, Thorsten R.; Endres, Stefan und Kobold, Sebastian
(2021):
Combined tumor-directed recruitment and protection from immune suppression enable CAR T cell efficacy in solid tumors.
In: Science Advances, Bd. 7, Nr. 24, eabi5781
Gaitzsch, Erik; Passerini, Verena; Khatamzas, Elham; Strobl, Carolin D.; Muenchhoff, Maximilian; Scherer, Clemens; Osterman, Andreas; Heide, Michael; Reischer, Anna; Subklewe, Marion; Leutbecher, Alexandra; Tast, Benjamin; Ruhle, Adrian; Weiglein, Tobias; Stecher, Stephanie-Susanne; Stemmler, Hans J.; Dreyling, Martin; Girl, Philipp; Georgi, Enrico; Woelfel, Roman; Mateyka, Laura; D'Ippolito, Elvira; Schober, Kilian; Busch, Dirk H.; Kager, Juliane; Spinner, Christoph D.; Treiber, Matthias; Rasch, Sebastian; Lahmer, Tobias; Iakoubov, Roman; Schneider, Jochen; Protzer, Ulrike; Winter, Christof; Ruland, Jürgen; Quante, Michael; Keppler, Oliver T.; Bergwelt-Baildon, Michael von; Hellmuth, Johannes und Weigert, Oliver
(2021):
COVID-19 in Patients Receiving CD20-depleting Immunochemotherapy for B-cell Lymphoma.
In: Hemasphere, Bd. 5, Nr. 7, e603
Heuser, Michael; Freeman, Sylvie D.; Ossenkoppele, Gert J.; Buccisano, Francesco; Hourigan, Christopher S.; Ngai, Lok Lam; Tettero, Jesse M.; Bachas, Costa; Baer, Constance; Bene, Marie-Christine; Bucklein, Veit; Czyz, Anna; Denys, Barbara; Dillon, Richard; Feuring-Buske, Michaela; Guzman, Monica L.; Haferlach, Torsten; Han, Lina; Herzig, Julia K.; Jorgensen, Jeffrey L.; Kern, Wolfgang; Konopleva, Marina Y.; Lacombe, Francis; Libura, Marta; Majchrzak, Agata; Maurillo, Luca; Ofran, Yishai; Philippe, Jan; Plesa, Adriana; Preudhomme, Claude; Ravandi, Farhad; Roumier, Christophe; Subklewe, Marion; Thol, Felicitas; Loosdrecht, Arjan A. van de; Reijden, Bert A. van der; Venditti, Adriano; Wierzbowska, Agnieszka; Valk, Peter J. M.; Wood, Brent L.; Walter, Roland B.; Thiede, Christian; Dohner, Konstanze; Roboz, Gail J. und Cloos, Jacqueline
(2021):
2021 Update on MRD in acute myeloid leukemia: a consensus document from the European LeukemiaNet MRD Working Party.
In: Blood, Bd. 138, Nr. 26: S. 2753-2767
Karschnia, Philipp; Blobner, Jens; Teske, Nico; Schöberl, Florian; Fitzinger, Esther; Dreyling, Martin; Tonn, Jörg-Christian; Thon, Niklas; Subklewe, Marion und Baumgarten, Louisa von
(2021):
CAR T-Cells for CNS Lymphoma: Driving into New Terrain?
In: Cancers, Bd. 13, Nr. 10, 2503
Karschnia, Philipp; Strübing, Felix; Teske, Nico; Blumenberg, Viktoria; Bücklein, Veit L.; Schmidt, Christian; Schöberl, Florian; Dimitriadis, Konstantinos; Forbrig, Robert; Stemmler, Hans-Joachim; Tonn, Jörg-Christian; Von Bergwelt-Baildon, Michael; Subklewe, Marion und Baumgarten, Louisa von
(2021):
Clinicopathologic Findings in Fatal Neurotoxicity After Adoptive Immunotherapy With CD19-Directed CAR T-Cells.
In: Hemasphere, Bd. 5, Nr. 3, e533
Karschnia, Philipp; Teske, Nico; Thon, Niklas; Subklewe, Marion; Tonn, Joerg-Christian; Dietrich, Jorg und Baumgarten, Louisa von
(2021):
Chimeric Antigen Receptor T Cells for Glioblastoma Current Concepts, Challenges, and Future Perspectives.
In: Neurology, Bd. 97, Nr. 5: S. 218-230
Lesch, Stefanie; Blumenberg, Viktoria; Stoiber, Stefan; Gottschlich, Adrian; Ogonek, Justyna; Cadilha, Bruno L.; Dantes, Zahra; Rataj, Felicitas; Dorman, Klara; Lutz, Johannes; Karches, Clara H.; Heise, Constanze; Kurzay, Mathias; Larimer, Benjamin M.; Grassmann, Simon; Rapp, Moritz; Nottebrock, Alessia; Kruger, Stephan; Tokarew, Nicholas; Metzger, Philipp; Hoerth, Christine; Benmebarek, Mohamed-Reda; Dhoqina, Dario; Grunmeier, Ruth; Seifert, Matthias; Oener, Arman; Umut, Oyku; Joaquina, Sandy; Vimeux, Lene; Tran, Thi; Hank, Thomas; Baba, Taisuke; Huynh, Duc; Megens, Remco T. A.; Janssen, Klaus-Peter; Jastroch, Martin; Lamp, Daniel; Ruehland, Svenja; Di Pilato, Mauro; Pruessmann, Jasper N.; Thomas, Moritz; Marr, Carsten; Ormanns, Steffen; Reischer, Anna; Hristov, Michael; Tartour, Eric; Donnadieu, Emmanuel; Rothenfusser, Simon; Duewell, Peter; Konig, Lars M.; Schnurr, Max; Subklewe, Marion; Liss, Andrew S.; Halama, Niels; Reichert, Maximilian; Mempel, Thorsten R.; Endres, Stefan und Kobold, Sebastian
(2021):
T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours.
In: Nature Biomedical Engineering, Bd. 5, Nr. 11
Rejeski, Kai; Kunz, Wolfgang G.; Rudelius, Martina; Bücklein, Veit; Blumenberg, Viktoria; Schmidt, Christian; Karschnia, Philipp; Schöberl, Florian; Dimitriadis, Konstantin; von Baumgarten, Louisa; Stemmler, Joachim; Weigert, Oliver; Dreyling, Martin; von Bergwelt-Baildon, Michael und Subklewe, Marion
(2021):
Severe Candida glabrata pancolitis and fatal Aspergillus fumigatus pulmonary infection in the setting of bone marrow aplasia after CD19-directed CAR T-cell therapy - a case report.
In: BMC Infectious Diseases, Bd. 21, Nr. 1, 121
Shah, Bijal D.; Ghobadi, Armin; Oluwole, Olalekan O.; Logan, Aaron C.; Boissel, Nicolas; Cassaday, Ryan D.; Leguay, Thibaut; Bishop, Michael R.; Topp, Max S.; Tzachanis, Dimitrios; O'Dwyer, Kristen M.; Arellano, Martha L.; Lin, Yi; Baer, Maria R.; Schiller, Gary J.; Park, Jae H.; Subklewe, Marion; Abedi, Mehrdad; Minnema, Monique C.; Wierda, William G.; DeAngelo, Daniel J.; Stiff, Patrick; Jeyakumar, Deepa; Feng, Chaoling; Dong, Jinghui; Shen, Tong; Milletti, Francesca; Rossi, John M.; Vezan, Remus; Masouleh, Behzad Kharabi und Houot, Roch
(2021):
KTE-X19 for relapsed or refractory adult B-cell acute lymphoblastic leukaemia: phase 2 results of the single-arm, open-label, multicentre ZUMA-3 study.
In: Lancet, Bd. 398, Nr. 10299: S. 491-502
Tahk, Siret; Vick, Binje; Hiller, Björn; Schmitt, Saskia; Marcinek, Anetta; Perini, Enrico D.; Leutbecher, Alexandra; Augsberger, Christian; Reischer, Anna; Tast, Benjamin; Humpe, Andreas; Jeremias, Irmela; Subklewe, Marion; Fenn, Nadja C. und Hopfner, Karl-Peter
(2021):
SIRP alpha-alpha CD123 fusion antibodies targeting CD123 in conjunction with CD47 blockade enhance the clearance of AML-initiating cells.
In: Journal of Hematology & Oncology, Bd. 14, Nr. 1, 155
Willier, Semjon; Rothamel, Paula; Hastreiter, Maximilian; Wilhelm, Jonas; Stenger, Dana; Blaeschke, Franziska; Rohlfs, Meino; Kaeuferle, Theresa; Schmid, Irene; Albert, Michael H.; Binder, Vera; Subklewe, Marion; Klein, Christoph und Feuchtinger, Tobias
(2021):
CLEC12A and CD33 coexpression as a preferential target for pediatric AML combinatorial immunotherapy.
In: Blood, Bd. 137, Nr. 8: S. 1037-1049
Winheim, Elena ORCID: https://orcid.org/0000-0002-0364-662X; Rinke, Linus ORCID: https://orcid.org/0000-0002-7563-7116; Lutz, Konstantin ORCID: https://orcid.org/0000-0002-6263-467X; Reischer, Anna; Leutbecher, Alexandra; Wolfram, Lina; Rausch, Lisa; Kranich, Jan ORCID: https://orcid.org/0000-0002-9928-4132; Wratil, Paul R.; Huber, Johanna E.; Baumjohann, Dirk ORCID: https://orcid.org/0000-0001-8385-8288; Rothenfusser, Simon ORCID: https://orcid.org/0000-0003-1151-7614; Schubert, Benjamin; Hilgendorff, Anne; Hellmuth, Johannes C.; Scherer, Clemens ORCID: https://orcid.org/0000-0003-2816-6793; Münchhoff, Maximilian ORCID: https://orcid.org/0000-0001-7016-0470; Bergwelt-Baildon, Michael von; Stark, Konstantin; Straub, Tobias ORCID: https://orcid.org/0000-0002-0547-0453; Brocker, Thomas; Keppler, Oliver T. ORCID: https://orcid.org/0000-0002-1384-8946; Subklewe, Marion und Krug, Anne B. ORCID: https://orcid.org/0000-0002-9556-7207
(2021):
Impaired function and delayed regeneration of dendritic cells in COVID-19.
In: PLOS Pathogens
17(10), e1009742
[PDF, 5MB]
2020
Schmitt, Saskia; Tahk, Siret; Lohner, Alina; Haenel, Gerulf; Maiser, Andreas; Hauke, Martina; Patel, Lubna; Rothe, Maurine; Josenhans, Christine; Leonhardt, Heinrich; Griffioen, Marieke; Deiser, Katrin; Fenn, Nadja C.; Hopfner, Karl-Peter und Subklewe, Marion
(12. November 2020):
Fusion of Bacterial Flagellin to a Dendritic Cell-Targeting αCD40 Antibody Construct Coupled With Viral or Leukemia-Specific Antigens Enhances Dendritic Cell Maturation and Activates Peptide-Responsive T Cells.
In: Frontiers in Immunology, Bd. 11, 602802: S. 1-16
[PDF, 3MB]
Lichtenegger, Felix S.; Schnorfeil, Frauke M.; Rothe, Maurine; Deiser, Katrin; Altmann, Torben; Bücklein, Veit L.; Köhnke, Thomas; Augsberger, Christian; Konstandin, Nikola P.; Spiekermann, Karsten; Moosmann, Andreas; Boehm, Stephan; Boxberg, Melanie; Heemskerk, Mirjam H. M.; Goerlich, Dennis; Wittmann, Georg; Wagner, Beate; Hiddemann, Wolfgang; Schendel, Dolores J.; Kvalheim, Gunnar; Bigalke, Iris und Subklewe, Marion
(2020):
Toll‐like receptor 7/8‐matured RNA‐transduced dendritic cells as post‐remission therapy in acute myeloid leukaemia: results of a phase I trial.
In: Clinical & Translational Immunology, Bd. 9, Nr. 3, e1117
[PDF, 1MB]
Herold, Tobias ORCID: https://orcid.org/0000-0002-9615-9432; Rothenberg-Thurley, Maja; Grunwald, Victoria V.; Janke, Hanna; Goerlich, Dennis; Sauerland, Maria C.; Konstandin, Nikola P.; Dufour, Annika; Schneider, Stephanie; Neusser, Michaela; Ksienzyk, Bianka; Greif, Philipp A.; Subklewe, Marion; Faldum, Andreas; Bohlander, Stefan K.; Braess, Jan; Wörmann, Bernhard; Krug, Utz; Berdel, Wolfgang E.; Hiddemann, Wolfgang; Spiekermann, Karsten und Metzeler, Klaus H.
(2020):
Validation and refinement of the revised 2017 European LeukemiaNet genetic risk stratification of acute myeloid leukemia.
In: Leukemia, Bd. 34: S. 3161-3172
[PDF, 2MB]
Winkelmann, Michael; Rejeski, Kai; Unterrainer, Marcus; Schmidt, Christian; Ruzicka, Michael; Ricke, Jens; Rudelius, Martina; Subklewe, Marion und Kunz, Wolfgang G. ORCID: https://orcid.org/0000-0002-5021-1952
(2020):
Transformation of diffuse large B cell lymphoma into dendritic sarcoma under CAR T cell therapy detected on 18F-FDG PET/CT.
In: European journal of nuclear medicine and molecular imaging
[PDF, 382kB]
Orth, Martin F.; Buecklein, Veit Leonhard; Kampmann, Eric; Subklewe, Marion; Noessner, Elfriede; Cidre-Aranaz, Florencia; Romero-Perez, Laura; Wehweck, Fabienne Sophie; Lindner, Lars; Issels, Rolf; Kirchner, Thomas; Altendorf-Hofmann, Annelore; Grunewald, Thomas G. P. und Knösel, Thomas
(2020):
A comparative view on the expression patterns of PD-L1 and PD-1 in soft tissue sarcomas.
In: Cancer Immunology Immunotherapy, Bd. 69, Nr. 7: S. 1353-1362
Ruzicka, Michael; König, Lars M.; Formisano, Simone; Boehmer, Daniel F. R.; Vick, Binje; Heuer, Eva-M.; Meinl, Hanna; Kocheise, Lorenz; Zeitlhoefler, Marcus; Ahlfeld, Julia; Kobold, Sebastian; Endres, Stefan; Subklewe, Marion; Duewell, Peter; Schnurr, Max; Jeremias, Irmela; Lichtenegger, Felix S. und Rothenfusser, Simon
(2020):
RIG-I-based immunotherapy enhances survival in preclinical AML models and sensitizes AML cells to checkpoint blockade.
In: Leukemia, Bd. 34, Nr. 4: S. 1017-1026
Montesinos, Pau; Roboz, Gail J.; Bulabois, Claude-Eric; Subklewe, Marion; Platzbecker, Uwe; Ofran, Yishai; Papayannidis, Cristina; Wierzbowska, Agnieszka; Shin, Ho Jin; Doronin, Vadim; Deneberg, Stefan; Yeh, Su-Peng; Ozcan, Mehmet Ali; Knapper, Steven; Cortes, Jorge; Pollyea, Daniel A.; Ossenkoppele, Gert; Giralt, Sergio; Doehner, Hartmut; Heuser, Michael; Xiu, Liang; Singh, Indrajeet; Huang, Fei; Larsen, Julie S. und Wei, Andrew H.
(2020):
Safety and efficacy of talacotuzumab plus decitabine or decitabine alone in patients with acute myeloid leukemia not eligible for chemotherapy: results from a multicenter, randomized, phase 2/3 study.
In: Leukemia, Bd. 35, Nr. 1: S. 62-74
Brauchle, Bettina; Goldstein, Rebecca L.; Karbowski, Christine M.; Henn, Anja; Li, Chi-Ming; Buecklein, Veit L.; Krupka, Christina; Boyle, Michael C.; Koppikar, Priya; Haubner, Sascha; Wahl, Joachim; Dahlhoff, Christoph; Raum, Tobias; Rardin, Matthew J.; Sastri, Christine; Rock, Dan A.; Bergwelt-Baildon, Michael von; Frank, Brendon; Metzeler, Klaus H.; Case, Ryan; Friedrich, Matthias; Balazs, Mercedesz; Spiekermann, Karsten; Coxon, Angela; Subklewe, Marion und Arvedson, Tara
(2020):
Characterization of a Novel FLT3 BITE Molecule for the Treatment of Acute Myeloid Leukemia.
In: Molecular Cancer Therapeutics, Bd. 19, Nr. 9: S. 1875-1888
Einsele, Hermann; Borghaei, Hossein; Orlowski, Robert Z.; Subklewe, Marion; Roboz, Gail J.; Zugmaier, Gerhard; Kufer, Peter; Iskander, Karim und Kantarjian, Hagop M.
(2020):
The BiTE (Bispecific T-Cell engager) platform: development and future potential of a targeted immuno-oncology therapy across Tumor Types.
In: Cancer, Bd. 126, Nr. 14: S. 3192-3201
2019
Grunwald, Victoria V.; Hentrich, Marcus; Schiel, Xaver; Dufour, Annika; Schneider, Stephanie; Neusser, Michaela; Subklewe, Marion; Fiegl, Michael; Hiddemann, Wolfgang; Spiekermann, Karsten; Rothenberg-Thurley, Maja und Metzeler, Klaus H.
(2019):
Patients with spontaneous remission of high-risk MDS and AML show persistent preleukemic clonal hematopoiesis.
In: Blood Advances, Bd. 3, Nr. 18: S. 2696-2699
Krüger, Stephan; Ilmer, Matthias; Kobold, Sebastian; Cadilha, Bruno L.; Endres, Stefan; Ormanns, Steffen; Schuebbe, Gesa; Renz, Bernhard W.; D'Haese, Jan G.; Schloesser, Hans; Heinemann, Volker; Subklewe, Marion; Böck, Stefan; Werner, Jens und Bergwelt-Baildon, Michael von
(2019):
Advances in cancer immunotherapy 2019-latest trends.
In: Journal of Experimental & Clinical Cancer Research, Bd. 38, 268
Van Acker, Heleen H.; Versteven, Maarten; Lichtenegger, Felix S.; Roex, Gils; Campillo-Davo, Diana; Lion, Eva; Subklewe, Marion; Van Tendeloo, Viggo F.; Berneman, Zwi N. und Anguille, Sebastien
(2019):
Dendritic Cell-Based Immunotherapy of Acute Myeloid Leukemia.
In: Journal of Clinical Medicine, Bd. 8, Nr. 5, 579
Thaler, Franziska S.; Thaller, Anna L.; Biljecki, Michelle; Schuh, Elisabeth; Winklmeier, Stephan; Mahler, Christoph F.; Gerhards, Ramona; Voelk, Stefanie; Schnorfeil, Frauke; Subklewe, Marion; Hohlfeld, Reinhard; Kuempfel, Tania und Meinl, Edgar
(2019):
Abundant glutamic acid decarboxylase (GAD)-reactive B cells in gad-antibody-associated neurological disorders.
In: Annals of Neurology, Bd. 85, Nr. 3: S. 448-454
[PDF, 2MB]
2018
Herold, Tobias; Jurinovic, Vindi; Batcha, Aarif Mohamed Nazeer; Bamopoulos, Stefanos A.; Rothenberg-Thurley, Maja; Ksienzyk, Bianka; Hartmann, Luise; Greif, Philipp A.; Phillippou-Massier, Julia; Krebs, Stefan; Blum, Helmut; Amler, Susanne; Schneider, Stephanie; Konstandin, Nikola P.; Sauerland, Maria Cristina; Görlich, Dennis; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Tischer, Johanna; Subklewe, Marion; Bohlander, Stefan K.; Braess, Jan; Hiddemann, Wolfgang; Metzeler, Klaus H.; Mansmann, Ulrich und Spiekermann, Karsten
(März 2018):
A 29-gene and cytogenetic score for the prediction of resistance to induction treatment in acute myeloid leukemia.
In: Haematologica, Bd. 103, Nr. 3: S. 456-65
Herrmann, Monika; Krupka, Christina; Deiser, Katrin; Brauchle, Bettina; Marcinek, Anetta; Wagner, Ana Ogrinc; Rataj, Felicitas; Mocikat, Ralph; Metzeler, Klaus H.; Spiekermann, Karsten; Kobold, Sebastian; Fenn, Nadja C.; Hopfner, Karl-Peter und Subklewe, Marion
(2018):
Bifunctional PD-1 x alpha CD3 x alpha CD33 fusion protein reverses adaptive immune escape in acute myeloid leukemia.
In: Blood, Bd. 132, Nr. 23: S. 2484-2494
Lichtenegger, Felix S.; Rothe, Maurine; Schnorfeil, Frauke M.; Deiser, Katrin; Krupka, Christina; Augsberger, Christian; Schlueter, Miriam; Neitz, Julia und Subklewe, Marion
(2018):
Targeting LAG-3 and PD-1 to Enhance T Cell Activation by Antigen-Presenting Cells.
In: Frontiers in Immunology, Bd. 9, 385
[PDF, 1MB]
Braciak, Todd A.; Roskopf, Claudia C.; Wildenhain, Sarah; Fenn, Nadja C.; Schiller, Christian B.; Schubert, Ingo A.; Jacob, Uwe; Honegger, Annemarie; Krupka, Christina; Subklewe, Marion; Spiekermann, Karsten; Hopfner, Karl-Peter; Fey, Georg H.; Aigner, Michael; Krause, Stefan; Mackensen, Andreas und Oduncu, Fuat S.
(2018):
Dual-targeting triplebody 33-16-123 (SPM-2) mediates effective redirected lysis of primary blasts from patients with a broad range of AML subtypes in combination with natural killer cells.
In: Oncoimmunology, Bd. 7, Nr. 9, e1472195
Bräss, Jan; Amler, Susanne; Kreuzer, Karl-Anton; Spiekermann, Karsten; Lindemann, Hans Walter; Lengfelder, Eva; Graeven, Ullrich; Staib, Peter; Ludwig, Wolf-Dieter; Biersack, Harald; Ko, Yon-Dschun; Uppenkamp, Michael J.; Wit, Maike de; Korsten, Stefan; Peceny, Rudolf; Gaska, Tobias; Schiel, Xaver; Behringer, Dirk M.; Kiehl, Michael G.; Zinngrebe, Bettina; Meckenstock, Gerald; Römer, Eva; Medgenberg, Dirk; Spaeth-Schwalbe, Ernst; Massenkeil, Gero; Hindahl, Heidrun; Schwerdtfeger, Rainer; Trenn, Guido; Sauerland, Cristina; Koch, Raphael; Lablans, Martin; Faldum, Andreas; Görlich, Dennis; Bohlander, Stefan K.; Schneider, Stephanie; Dufour, Annika; Buske, Christian; Fiegl, Michael; Subklewe, Marion; Bräss, Birgit; Unterhalt, Michael; Baumgartner, Anja; Wörmann, Bernhard; Beelen, Dietrich und Hiddemann, Wolfgang
(2018):
Sequential high-dose cytarabine and mitoxantrone (S-HAM) versus standard double induction in acute myeloid leukemia-a phase 3 study.
In: Leukemia, Bd. 32, Nr. 12: S. 2558-2571
Zimmermann, Heiner; Babel, Nina; Dierickx, Daan; Morschhauser, Franck; Mollee, Peter; Zaucha, Jan M.; Dreyling, Martin H.; Dührsen, Ulrich; Reinke, Petra; Verhöf, Gregor; Subklewe, Marion; Hüttmann, Andreas; Tousseyn, Thomas; Bachy, Emmanuel; Hauser, Ingeborg A.; Tarella, Corrado; Van den Neste, Eric; Gheysens, Olivier; Anagnostopoulos, Ioannis; Leblond, Veronique; Riess, Hanno; Choquet, Sylvain und Trappe, Ralf U.
(2018):
Immunosuppression Is Associated With Clinical Features and Relapse Risk of B Cell Posttransplant Lymphoproliferative Disorder: A Retrospective Analysis Based on the Prospective, International, Multicenter PTLD-1 Trials.
In: Transplantation, Bd. 102, Nr. 11: S. 1914-1923
[PDF, 0B]
Zimmermann, Heiner; Denecke, Timm; Dreyling, Martin H.; Franzius, Christiane; Reinke, Petra; Subklewe, Marion; Amthauer, Holger; Kneba, Michael; Riess, Hanno und Trappe, Ralf U.
(2018):
End-of-Treatment Positron Emission Tomography After Uniform First-Line Therapy of B-Cell Posttransplant Lymphoproliferative Disorder Identifies Patients at Low Risk of Relapse in the Prospective German PTLD Registry.
In: Transplantation, Bd. 102, Nr. 5: S. 868-875
[PDF, 0B]
Prassek, Victoria V.; Rothenberg-Thurley, Maja; Sauerland, Maria C.; Herold, Tobias; Janke, Hanna; Ksienzyk, Bianka; Konstandin, Nikola P.; Goerlich, Dennis; Krug, Utz; Faldum, Andreas; Berdel, Wolfgang E.; Wörmann, Bernhard; Braess, Jan; Schneider, Stephanie; Subklewe, Marion; Bohlander, Stefan K.; Hiddemann, Wolfgang; Spiekermann, Karsten und Metzeler, Klaus H.
(2018):
Genetics of acute myeloid leukemia in the elderly: mutation spectrum and clinical impact in intensively treated patients aged 75 years or older.
In: Haematologica, Bd. 103, Nr. 11: S. 1853-1861
[PDF, 1MB]
Rothenberg-Thurley, Maja; Amler, Susanne; Goerlich, Dennis; Köhnke, Thomas; Konstandin, Nikola P.; Schneider, Stephanie; Sauerland, Maria C.; Herold, Tobias; Hubmann, Max; Ksienzyk, Bianka; Zellmeier, Evelyn; Bohlander, Stefan K.; Subklewe, Marion; Faldum, Andreas; Hiddemann, Wolfgang; Braess, Jan; Spiekermann, Karsten und Metzeler, Klaus H.
(2018):
Persistence of pre-leukemic clones during first remission and risk of relapse in acute myeloid leukemia.
In: Leukemia, Bd. 32, Nr. 7: S. 1598-1608
Shimabukuro-Vornhagen, Alexander; Gödel, Philipp; Subklewe, Marion; Stemmler, Hans Joachim; Schlößer, Hans Anton; Schlaak, Max; Kochanek, Matthias; Böll, Boris und Bergwelt-Baildon, Michael S. von
(2018):
Cytokine release syndrome.
In: Journal for Immunotherapy of Cancer
6:56
[PDF, 1MB]
2017
Ponce, Laia Pascual; Fenn, Nadja C.; Moritz, Nadine; Krupka, Christina; Kozik, Jan-Hendrik; Lauber, Kirsten; Subklewe, Marion und Hopfner, Karl-Peter
(2017):
SIRP alpha-antibody fusion proteins stimulate phagocytosis and promote elimination of acute myeloid leukemia cells.
In: Oncotarget, Bd. 8, Nr. 7: S. 11284-11301
[PDF, 6MB]
Köhnke, Thomas; Wittmann, Veronika K.; Bücklein, Veit L.; Lichtenegger, Felix; Pasalic, Zlatana; Hiddemann, Wolfgang; Spiekermann, Karsten und Subklewe, Marion
(2017):
Diagnosis of CLL revisited: increased specificity by a modified five-marker scoring system including CD200.
In: British Journal of Haematology, Bd. 179, Nr. 3: S. 480-487
Krupka, Christina; Lichtenegger, Felix S.; Kohnke, Thomas; Bogeholz, Jan; Bucklein, Veit; Roiss, Michael; Altmann, Torben; Do, To Uyen; Dusek, Rachel; Wilson, Keith; Bisht, Arnima; Terrett, Jon; Aud, Dee; Pombo-Villar, Esteban; Rohlff, Christian; Hiddemann, Wolfgang und Subklewe, Marion
(2017):
Targeting CD157 in AML using a novel, Fc-engineered antibody construct.
In: Oncotarget, Bd. 8, Nr. 22: S. 35707-35717
[PDF, 1MB]
Sandhöfer, Nadine; Metzeler, Klaus H.; Kakadia, Purvi M.; Pasalic, Zlatana; Hiddemann, Wolfgang; Neusser, Michaela; Steinlein, Ortrud; Fiegl, Michael; Subklewe, Marion; Spiekermann, Karsten; Bohlander, Stefan K.; Schneider, Stephanie und Bräss, Jan
(2017):
A fluorescence in situ hybridization-based screen allows rapid detection of adverse cytogenetic alterations in patients with acute myeloid leukemia.
In: Genes Chromosomes & Cancer, Bd. 56, Nr. 8: S. 632-638
Gaidt, Moritz M.; Ebert, Thomas S.; Chauhan, Dhruv; Ramshorn, Katharina; Pinci, Francesca; Zuber, Sarah; O'Duill, Fionan; Schmid-Burgk, Jonathan L.; Hoss, Florian; Buhmann, Raymund; Wittmann, Georg; Latz, Eicke; Subklewe, Marion und Hornung, Veit
(2017):
The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3.
In: Cell, Bd. 171, Nr. 5: S. 1110-1124
Trappe, Ralf U.; Dierickx, Daan; Zimmermann, Heiner; Morschhauser, Franck; Mollee, Peter; Zaucha, Jan M.; Dreyling, Martin H.; Dührsen, Ulrich; Reinke, Petra; Verhoef, Gregor; Subklewe, Marion; Hüttmann, Andreas; Tousseyn, Thomas; Salles, Gilles; Kliem, Volker; Hauser, Ingeborg A.; Tarella, Corrado; Neste, Eric van den; Gheysens, Olivier; Anagnostopoulos, Ioannis; Leblond, Veronique; Riess, Hanno und Choquet, Sylvain
(2017):
Response to Rituximab Induction Is a Predictive Marker in B-Cell Post-Transplant Lymphoproliferative Disorder and Allows Successful Stratification Into Rituximab or R-CHOP Consolidation in an International, Prospective, Multicenter Phase II Trial.
In: Journal of Clinical Oncology, Bd. 35, Nr. 5:
536-+
Braciak, T.; Fenn, N.; Wildenhain, S.; Schiller, C.; Roskopf, C.; Schubert, I.; Jacob, U.; Hopfner, K. P.; Aigner, M.; Mackensen, A.; Subklewe, Marion; Spiekermann, K.; Fey, G. H. und Oduncu, F.
(2017):
Elimination of Cells from Patients with Different Subtypes of AML by Dual-Targeting Triplebody 33-16-123 (SPM-2).
In: Annals of Hematology, Bd. 96:
S81-S81
Krupka, C.; Lindl, B.; Kischel, R.; Kufer, P.; Lichtenegger, F. S.; Köhnke, T.; Augsberger, C.; Altmann, T.; Spiekermann, K.; Hiddemann, W. und Subklewe, Marion
(2017):
Influence of Cytoreductive and Immunmodulatory Drugs on Bispecific T-Cell Engager-Based Approaches in AML.
In: Annals of Hematology, Bd. 96:
S81-S82
Prassek, V. V.; Rothenberg-Thurley, M.; Herold, T.; Amler, S.; Sauerland, M. C.; Goerlich, D.; Janke, H.; Schneider, S.; Subklewe, Marion; Krug, U.; Faldum, A.; Berdel, W. E.; Woermann, B.; Buechner, T.; Braess, J.; Hiddemann, W.; Spiekermann, K. und Metzeler, K. H.
(2017):
AML Patients Aged >= 75 Years Enrolled into AMLCG Trials: Do Gene Mutations Impact Clinical Outcome in Very Old, Intensively Treated Patients?
In: Annals of Hematology, Bd. 96:
S63-S63
Rothenberg-Thurley, M.; Amler, S.; Goerlich, D.; Sauerland, M. C.; Schneider, S.; Konstandin, N. P.; Batcha, A. M.; Ksienzyk, B.; Zellmeier, E.; Mansmann, Ulrich; Subklewe, Marion; Bohlander, S. K.; Faldum, A.; Hiddemann, W.; Spiekermann, K.; Braess, J. und Metzeler, Klaus H.
(2017):
Persistence of Driver Mutations during Complete Remission Associates with Shorter Survival and Contributes to the Inferior Outcomes of Elderly Patients with Acute Myeloid Leukemia.
In: Annals of Hematology, Bd. 96:
S31-S32
2016
Herhaus, Peter; Habringer, Stefan; Philipp-Abbrederis, Kathrin; Vag, Tibor; Gerngross, Carlos; Schottelius, Margret; Slotta-Huspenina, Julia; Steiger, Katja; Altmann, Torben; Weisser, Tanja; Steidle, Sabine; Schick, Markus; Jacobs, Laura; Slawska, Jolanta; Müller-Thomas, Catharina; Verbeek, Mareike; Subklewe, Marion; Peschel, Christian; Wester, Hans-Jürgen; Schwaiger, Markus; Götze, Katharina und Keller, Ulrich
(2016):
Targeted positron emission tomography imaging of CXCR4 expression in patients with acute myeloid leukemia.
In: Haematologica, Bd. 101, Nr. 8: S. 932-940
[PDF, 2MB]
Schuh, Elisabeth; Berer, Kerstin; Mulazzani, Matthias; Feil, Katharina; Meinl, Ingrid; Lahm, Harald; Krane, Markus; Lange, Rüdiger; Pfannes, Kristina; Subklewe, Marion; Gürkov, Robert; Bradl, Monika; Hohlfeld, Reinhard; Kümpfel, Tania; Meinl, Edgar und Krumbholz, Markus
(2016):
Features of Human CD3(+)CD20(+) T Cells.
In: Journal of Immunology, Bd. 197, Nr. 4: S. 1111-1117
Metzeler, Klaus H.; Herold, Tobias; Rothenberg-Thurley, Maja; Amler, Susanne; Sauerland, Maria C.; Görlich, Dennis; Schneider, Stephanie; Konstandin, Nikola P.; Dufour, Annika; Bräundl, Kathrin; Ksienzyk, Bianka; Zellmeier, Evelyn; Hartmann, Luise; Greif, Philipp A.; Fiegl, Michael; Subklewe, Marion; Bohlander, Stefan K.; Krug, Utz; Faldum, Andreas; Berdel, Wolfgang E.; Wörmann, Bernhard; Büchner, Thomas; Hiddemann, Wolfgang; Braess, Jan und Spiekermann, Karsten
(2016):
Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia.
In: Blood, Bd. 128, Nr. 5: S. 686-698
Krupka, Christina; Kufer, Peter; Kischel, Roman; Zugmaier, Gerhard; Köhnke, Thomas; Lichtenegger, Felix; Altmann, Torben; Spiekermann, Karsten; Vick, Binje; Jeremias, Irmela; Hiddemann, Wolfgang; Riethmüller, Gert und Subklewe, Marion
(2016):
Characterization of covariables modulating CD33/CD3 BITE antibody construct mediated cytotoxicity against primary AML cells.
In: Cancer Immunology Research, Bd. 4, Nr. 1
Lichtenegger, Felix S.; Schnorfeil, Frauke M.; Köhnke, Thomas; Altmann, Torben; Bücklein, Veit; Moosmann, Andreas; Brüggemann, Monika; Wagner, Beate; Hiddemann, Wolfgang; Bigalke, Iris; Kvalheim, Gunnar und Subklewe, Marion
(2016):
Next-generation dendritic cell vaccination in postremission therapy of AML: Results of a clinical phase I trial.
In: Cancer Immunology Research, Bd. 4, Nr. 1
Zoellner, Anna-Katharina; Fritsch, Susanne; Prevalsek, Dusan; Köhnke, Thomas; Hubmann, Max; Lippl, Stephanie; Kruger, Stephan; Hellmuth, Johannes; Mumm, Friederike; Ledderose, Georg; Barlow, Sophie; Subklewe, Marion; Spiekermann, Karsten; Hiddemann, Wolfgang; Albert, Michael H.; Schmid, Christoph; Hausmann, Andreas und Tischer, Johanna
(2016):
T-Cell-Replete HLA-Haploidentical Transplantation Using Post-Transplantation High-Dose Cyclophosphamide in High Risk and Advanced ALL: Feasibility and Early Outcome.
In: Biology of Blood and Marrow Transplantation, Bd. 22, Nr. 3:
S364-S364
Bücklein, Veit; Adunka, Tina; Mendler, Anna N.; Issels, Rolf; Subklewe, Marion; Schmollinger, Jan C. und Noessner, Elfriede
(2016):
Progressive natural killer cell dysfunction associated with alterations in subset proportions and receptor expression in soft-tissue sarcoma patients.
In: Oncoimmunology, Bd. 5, Nr. 7, e1178421
2015
Vick, Binje; Rothenberg, Maja; Sandhöfer, Nadine; Carlet, Michela; Finkenzeller, Cornelia; Krupka, Christina; Grunert, Michaela; Trumpp, Andreas; Corbacioglu, Selim; Ebinger, Martin; André, Maya C.; Hiddemann, Wolfgang; Schneider, Stephanie; Subklewe, Marion; Metzeler, Klaus H.; Spiekermann, Karsten und Jeremias, Irmela
(2015):
An Advanced Preclinical Mouse Model for Acute Myeloid Leukemia Using Patients' Cells of Various Genetic Subgroups and In Vivo Bioluminescence Imaging.
In: PLOS ONE
10(3), e0120925
[PDF, 3MB]
2014
Hubmann, Max; Köhnke, Thomas; Hoster, Eva; Schneider, Stephanie; Dufour, Annika; Zellmeier, Evelyn; Fiegl, Michael; Braess, Jan; Bohlander, Stefan K.; Subklewe, Marion; Sauerland, Maria-Cristina; Berdel, Wolfgang E.; Büchner, Thomas; Woermann, Bernhard; Hiddemann, Wolfgang und Spiekermann, Karsten
(2014):
Molecular response assessment by quantitative real-time polymerase chain reaction after induction therapy in NPM1-mutated patients identifies those at high risk of relapse.
In: Haematologica, Bd. 99, Nr. 8: S. 1317-1325
[PDF, 838kB]
Janke, Hanna; Pastore, Friederike; Schumacher, Daniela; Herold, Tobias; Hopfner, Karl-Peter; Schneider, Stephanie; Berdel, Wolfgang E.; Büchner, Thomas; Woermann, Bernhard J.; Subklewe, Marion; Bohlander, Stefan K.; Hiddemann, Wolfgang; Spiekermann, Karsten und Polzer, Harald
(2014):
Activating FLT3 Mutants Show Distinct Gain-of-Function Phenotypes In Vitro and a Characteristic Signaling Pathway Profile Associated with Prognosis in Acute Myeloid Leukemia.
In: PLOS ONE
9(3), e89560
[PDF, 2MB]
2011
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