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Anzahl der Publikationen: 21
Zeitschriftenartikel
Bartos, Laura M.; Kunte, Sebastian T.; Beumers, Philipp; Xiang, Xianyuan; Wind, Karin; Ziegler, Sibylle; Bartenstein, Peter; Choi, Hongyoon; Lee, Dong Soo; Haass, Christian; Baumgarten, Louisa von; Tahirovic, Sabina; Albert, Nathalie L.; Lindner, Simon und Brendel, Matthias
(2022):
Single-Cell Radiotracer Allocation via Immunomagnetic Sorting to Disentangle PET Signals at Cellular Resolution.
In: Journal of Nuclear Medicine, Bd. 63, Nr. 10: S. 1459-1462
Biechele, Gloria; Monasor, Laura Sebastian; Wind, Karin; Blume, Tanja; Parhizkar, Samira; Arzberger, Thomas; Sacher, Christian; Beyer, Leonie; Eckenweber, Florian; Gildehaus, Franz-Josef; Ungern-Sternberg, Barbara von; Willem, Michael; Bartenstein, Peter; Cumming, Paul; Rominger, Axel; Herms, Jochen; Lichtenthaler, Stefan F.; Haass, Christian; Tahirovic, Sabina und Brendel, Matthias
(2022):
Glitter in the Darkness? Nonfibrillar beta-Amyloid Plaque Components Significantly Impact the beta-Amyloid PET Signal in Mouse Models of Alzheimer Disease.
In: Journal of Nuclear Medicine, Bd. 63, Nr. 1: S. 117-124
Xiang, Xianyuan; Wind, Karin; Wiedemann, Thomas; Blume, Tanja; Shi, Yuan; Briel, Nils; Beyer, Leonie; Biechele, Gloria; Eckenweber, Florian; Zatcepin, Artem; Lammich, Sven; Ribicic, Sara; Tahirovic, Sabina; Willem, Michael; Deussing, Maximilian; Palleis, Carla; Rauchmann, Boris-Stephan; Gildehaus, Franz-Josef; Lindner, Simon; Spitz, Charlotte; Franzmeier, Nicolai; Baumann, Karlheinz; Rominger, Axel; Bartenstein, Peter; Ziegler, Sibylle; Drzezga, Alexander; Respondek, Gesine; Buerger, Katharina; Perneczky, Robert; Levin, Johannes; Hoeglinger, Guenter U.; Herms, Jochen; Haass, Christian und Brendel, Matthias
(2021):
Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases.
In: Science Translational Medicine, Bd. 13, Nr. 615, eabe5640
d'Errico, Paolo; Ziegler-Waldkirch, Stephanie; Aires, Vanessa; Hoffmann, Philippe; Mezoe, Charlotte; Erny, Daniel; Monasor, Laura Sebastian; Liebscher, Sabine; Ravi, Vidhya M.; Joseph, Kevin; Schnell, Oliver; Kierdorf, Katrin; Staszewski, Ori; Tahirovic, Sabina; Prinz, Marco und Meyer-Luehmann, Melanie
(2021):
Microglia contribute to the propagation of A beta into unaffected brain tissue.
In: Nature Neuroscience, Bd. 25, Nr. 1: S. 20-25
Colombo, Alessio; Dinkel, Lina; Mueller, Stephan A.; Monasor, Laura Sebastian; Schifferer, Martina; Cantuti-Castelvetri, Ludovico; Koenig, Jasmin; Vidatic, Lea; Bremova-Ertl, Tatiana; Lieberman, Andrew P.; Hecimovic, Silva; Simons, Mikael; Lichtenthaler, Stefan F.; Strupp, Michael; Schneider, Susanne A. und Tahirovic, Sabina
(2021):
Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia.
In: Nature Communications, Bd. 12, Nr. 1, 1158
[PDF, 7MB]
Colombo, Alessio Vittorio; Sadler, Rebecca Katie; Llovera, Gemma; Singh, Vikramjeet; Roth, Stefan; Heindl, Steffanie; Monasor, Laura Sebastian; Verhoeven, Aswin; Peters, Finn; Parhizkar, Samira; Kamp, Frits; de Aguero, Mercedes Gomez; MacPherson, Andrew J.; Winkler, Edith; Herms, Jochen; Benakis, Corinne; Dichgans, Martin; Steiner, Harald; Giera, Martin; Haass, Christian; Tahirovic, Sabina und Liesz, Arthur
(2021):
Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition.
In: eLife, Bd. 10, e59826
[PDF, 2MB]
Biechele, Gloria; Wind, Karin; Blume, Tanja; Sacher, Christian; Beyer, Leonie; Eckenweber, Florian; Franzmeier, Nicolai; Ewers, Michael; Zott, Benedikt; Lindner, Simon; Gildehaus, Franz-Josef; Ungern-Sternberg, Barbara von; Tahirovic, Sabina; Willem, Michael; Bartenstein, Peter; Cumming, Paul; Rominger, Axel; Herms, Jochen und Brendel, Matthias
(2021):
Microglial activation in the right amygdala-entorhinal-hippocampal complex is associated with preserved spatial learning in mice.
In: Neuroimage, Bd. 230, 117707
Bettegazzi, Barbara; Sebastian Monasor, Laura; Bellani, Serena; Codazzi, Franca; Restelli, Lisa Michelle; Colombo, Alessio Vittorio; Deigendesch, Nikolaus; Frank, Stephan; Saito, Takashi; Saido, Takaomi C.; Lammich, Sven; Tahirovic, Sabina; Grohovaz, Fabio und Zacchetti, Daniele
(2021):
Casein Kinase 2 dependent phosphorylation of eIF4B regulates BACE1 expression in Alzheimer's disease.
In: Cell Death & Disease, Bd. 12, Nr. 8, 769
Schlepckow, Kai; Monroe, Kathryn M.; Kleinberger, Gernot; Cantuti‐Castelvetri, Ludovico; Parhizkar, Samira; Xia, Dan; Willem, Michael; Werner, Georg; Pettkus, Nadine; Brunner, Bettina; Sülzen, Alice; Nuscher, Brigitte; Hampel, Heike; Xiang, Xianyuan; Feederle, Regina; Tahirovic, Sabina; Park, Joshua I.; Prorok, Rachel; Mahon, Cathal; Liang, Chun‐Chi; Shi, Ju; Kim, Do Jin; Sabelström, Hanna; Huang, Fen; Paolo, Gilbert di; Simons, Mikael; Lewcock, Joseph W. und Haass, Christian 
ORCID: https://orcid.org/0000-0002-4869-1627
(7. April 2020):
Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region.
, Bd. 12, Nr. 4, e11227
[PDF, 4MB]
ORCID: https://orcid.org/0000-0002-4869-1627
(7. April 2020):
Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region.
, Bd. 12, Nr. 4, e11227
[PDF, 4MB]
Sacher, Christian; Blume, Tanja; Beyer, Leonie; Biechele, Gloria; Sauerbeck, Julia; Eckenweber, Florian; Deussing, Maximilian; Focke, Carola; Parhizkar, Samira; Lindner, Simon; Gildehaus, Franz-Josef; Ungern-Sternberg, Barbara von; Baumann, Karlheinz; Tahirovic, Sabina; Kleinberger, Gernot; Willem, Michael; Haass, Christian; Bartenstein, Peter; Cumming, Paul; Rominger, Axel; Herms, Jochen und Brendel, Matthias
(2020):
Asymmetry of Fibrillar Plaque Burden in Amyloid Mouse Models.
In: Journal of Nuclear Medicine, Bd. 61, Nr. 12
Lewcock, Joseph W.; Schlepckow, Kai; Di Paolo, Gilbert; Tahirovic, Sabina; Monroe, Kathryn M. und Haass, Christian
(2020):
Emerging Microglia Biology Defines Novel Therapeutic Approaches for Alzheimer's Disease.
In: Neuron, Bd. 108, Nr. 5: S. 801-821
Monasor, Laura Sebastian; Müller, Stephan A.; Colombo, Alessio Vittorio; Tanrioever, Gaye; König, Jasmin; Roth, Stefan; Liesz, Arthur; Berghofer, Anna; Piechotta, Anke; Prestel, Matthias; Saito, Takashi; Saido, Takaomi C.; Herms, Jochen; Willem, Michael; Haass, Christian; Lichtenthaler, Stefan F. und Tahirovic, Sabina
(2020):
Fibrillar Aβ (beta) triggers microglial proteome alterations and dysfunction in Alzheimer mouse models.
In: eLife, Bd. 9, e54083
[PDF, 14MB]
Parhizkar, Samira; Arzberger, Thomas; Brendel, Matthias; Kleinberger, Gernot; Deussing, Maximilian; Focke, Carola; Nuscher, Brigitte; Xiong, Monica; Ghasemigharagoz, Alireza; Katzmarski, Natalie; Krasemann, Susanne; Lichtenthaler, Stefan F.; Müller, Stephan A.; Colombo, Alessio; Monasor, Laura Sebastian; Tahirovic, Sabina; Herms, Jochen; Willem, Michael; Pettkus, Nadine; Butovsky, Oleg; Bartenstein, Peter; Edbauer, Dieter; Rominger, Axel; Ertuerk, Ali; Grathwohl, Stefan A.; Neher, Jonas J.; Holtzman, David M.; Meyer-Luehmann, Melanie und Haass, Christian
(2019):
Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.
In: Nature Neuroscience, Bd. 22, Nr. 2
Schneider, Susanne A.; Tahirovic, Sabina; Hardy, John; Strupp, Michael und Bremova-Ertl, Tatiana
(2019):
Do heterozygous mutations of Niemann-Pick type C predispose to late-onset neurodegeneration: a review of the literature.
In: Journal of Neurology
Montagna, Elena; Crux, Sophie; Luckner, Manja; Herber, Julia; Colonnbo, Alessio; Marinkovic, Petar; Tahirovic, Sabina; Lichtenthaler, Stefan F.; Wanner, Gerhard; Müller, Ulrike C.; Sgobio, Carmelo und Herms, Jochen
(2019):
In vivo Ca2+ imaging of astrocytic microdomains reveals a critical role of the amyloid precursor protein for mitochondria.
In: Glia, Bd. 67, Nr. 5: S. 985-998
Götzl, Julia K.; Brendel, Matthias; Werner, Georg; Parhizkar, Samira; Monasor, Laura Sebastian; Kleinberger, Gernot; Colombo, Alessio‐Vittorio; Deussing, Maximilian; Wagner, Matias; Winkelmann, Juliane; Diehl‐Schmid, Janine; Levin, Johannes; Fellerer, Katrin; Reifschneider, Anika; Bultmann, Sebastian; Bartenstein, Peter; Rominger, Axel; Tahirovic, Sabina; Smith, Scott T.; Madore, Charlotte; Butovsky, Oleg; Capell, Anja und Haass, Christian
(2019):
Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism.
In: Embo Molecular Medicine, Bd. 11, Nr. 6
[PDF, 1MB]
Causevic, Mirsada; Dominko, Kristina; Malnar, Martina; Vidatic, Lea; Cermak, Stjepko; Pigoni, Martina; Kuhn, Peer-Hendrik; Colombo, Alessio; Havas, Daniel; Flunkert, Stefanie; McDonald, Jessica; Gunnersen, Jenny M.; Hutter-Paier, Birgit; Tahirovic, Sabina; Windisch, Manfred; Krainc, Dimitri; Lichtenthaler, Stefan F. und Hecimovic, Silva
(2018):
BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains.
In: PLOS One 13(7), e0200344 [PDF, 74MB]
In: PLOS One 13(7), e0200344 [PDF, 74MB]
Götzl, Julia K.; Colombo, Alessio-Vittorio; Fellerer, Katrin; Reifschneider, Anika; Werner, Georg; Tahirovic, Sabina; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627 und Capell, Anja
(2018):
Early lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout mice.
In: Molecular Neurodegeneration
13:48
[PDF, 4MB]
ORCID: https://orcid.org/0000-0002-4869-1627 und Capell, Anja
(2018):
Early lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout mice.
In: Molecular Neurodegeneration
13:48
[PDF, 4MB]
Daria, Anna; Colombo, Alessio; Llovera, Gemma; Hampel, Heike; Willem, Michael; Liesz, Arthur; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627 und Tahirovic, Sabina
(2017):
Young microglia restore amyloid plaque clearance of aged microglia.
In: Embo Journal, Bd. 36, Nr. 5: S. 583-603
ORCID: https://orcid.org/0000-0002-4869-1627 und Tahirovic, Sabina
(2017):
Young microglia restore amyloid plaque clearance of aged microglia.
In: Embo Journal, Bd. 36, Nr. 5: S. 583-603
Mazaheri, Fargol; Snaidero, Nicolas; Kleinberger, Gernot; Madore, Charlotte; Daria, Anna; Werner, Georg; Krasemann, Susanne; Capell, Anja; Trümbach, Dietrich; Wurst, Wolfgang; Brunner, Bettina; Bultmann, Sebastian; Tahirovic, Sabina; Kerschensteiner, Martin; Misgeld, Thomas; Butovsky, Oleg und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2017):
TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.
In: Embo Reports, Bd. 18, Nr. 7: S. 1186-1198
ORCID: https://orcid.org/0000-0002-4869-1627
(2017):
TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.
In: Embo Reports, Bd. 18, Nr. 7: S. 1186-1198
Schwenk, Benjamin M.; Hartmann, Hannelore; Serdaroglu, Alperen; Schludi, Martin H.; Hornburg, Daniel; Meissner, Felix; Orozco, Denise; Colombo, Alessio; Tahirovic, Sabina; Michaelsen, Meike; Schreiber, Franziska; Haupt, Simone; Peitz, Michael; Bruestle, Oliver; Küpper, Clemens; Klopstock, Thomas; Otto, Markus; Ludolph, Albert C.; Arzberger, Thomas; Kuhn, Peer-Hendrik und Edbauer, Dieter
(2016):
TDP-43 loss of function inhibits endosomal trafficking and alters trophic signaling in neurons.
In: Embo Journal, Bd. 35, Nr. 21: S. 2350-2370