Anzahl der Publikationen: 9
2022
Müller, Markus; Niemeyer, Konstantin; Urban, Nicole; Ojha, Navin K.; Zufall, Frank; Leinders-Zufall, Trese; Schäfer, Michael und Thorn-Seshold, Oliver
(2022):
BTDAzo: A Photoswitchable TRPC5 Channel Activator.
In: Angewandte Chemie International Edition, Bd. 61, Nr. 36
[PDF, 11MB]
2021
Rühl, Philipp; Rosato, Anna Scotto; Urban, Nicole; Gerndt, Susanne; Tang, Rachel; Abrahamian, Carla; Leser, Charlotte; Sheng, Jiansong; Jha, Archana; Vollmer, Günter; Schaefer, Michael; Bracher, Franz ORCID: https://orcid.org/0000-0003-0009-8629 und Grimm, Christian
(2021):
Estradiol analogs attenuate autophagy, cell migration and invasion by direct and selective inhibition of TRPML1, independent of estrogen receptors.
In: Scientific reports, Bd. 11, Nr. 1, 8313
[PDF, 7MB]
Leser, Charlotte; Keller, Marco; Gerndt, Susanne; Urban, Nicole; Chen, Cheng-Chang; Schaefer, Michael; Grimm, Christian und Bracher, Franz
(2021):
Chemical and pharmacological characterization of the TRPML calcium channel blockers ML-SI1 and ML-SI3.
In: European Journal of Medicinal Chemistry, Bd. 210, 112966
Müller, Martin; Gerndt, Susanne; Chao, Yu-Kai; Zisis, Themistoklis; Ong, Nam Phuong Nguyen; Gerwien, Aaron; Urban, Nicole; Müller, Christoph; Gegenfurtner, Florian A.; Geisslinger, Franz; Ortler, Carina; Chen, Cheng-Chang; Zahler, Stefan; Biel, Martin; Schäfer, Michael; Grimm, Christian; Bracher, Franz; Vollmar, Angelika M. und Bartel, Karin
(2021):
Gene editing and synthetically accessible inhibitors reveal role for TPC2 in HCC cell proliferation and tumor growth.
In: Cell Chemical Biology, Bd. 28, Nr. 8:
1119-
Ruehl, Philipp; Rosato, Anna Scotto; Urban, Nicole; Gerndt, Susanne; Tang, Rachel; Abrahamian, Carla; Leser, Charlotte; Sheng, Jiansong; Jha, Archana; Vollmer, Guenter; Schaefer, Michael; Bracher, Franz und Grimm, Christian
(2021):
Estradiol analogs attenuate autophagy, cell migration and invasion by direct and selective inhibition of TRPML1, independent of estrogen receptors.
In: Scientific Reports, Bd. 11, Nr. 1, 8313
2020
Gerndt, Susanne; Chen, Cheng-Chang; Chao, Yu-Kai; Yuan, Yu; Burgstaller, Sandra; Rosato, Anna Scotto; Krogsaeter, Einar; Urban, Nicole; Jacob, Katharina; Ong, Nam Phuong Nguyen; Miller, Meghan T.; Keller, Marco; Vollmar, Angelika M.; Gudermann, Thomas; Zierler, Susanna; Schredelseker, Johann; Schaefer, Michael; Biel, Martin; Malli, Roland; Wahl-Schott, Christian; Bracher, Franz; Patel, Sandip und Grimm, Christian
(2020):
Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function.
In: eLife, Bd. 9, e54712
[PDF, 4MB]
2018
Haefner, Stephanie; Burg, Finn; Kannler, Martina; Urban, Nicole; Mayer, Peter; Dietrich, Alexander; Trauner, Dirk; Broichhagen, Johannes und Schaefer, Michael
(2018):
A (+)-Larixol Congener with High Affinity and Subtype Selectivity toward TRPC6.
In: Chemmedchem, Bd. 13, Nr. 10: S. 1028-1035
2014
Chen, Cheng-Chang; Keller, Marco; Hess, Martin; Schiffmann, Raphael; Urban, Nicole; Wolfgardt, Annette; Schaefer, Michael; Bracher, Franz; Biel, Martin; Wahl-Schott, Christian und Grimm, Christian
(2014):
A small molecule restores function to TRPML1 mutant isoforms responsible for mucolipidosis type IV.
In: Nature Communications, Bd. 5, 4681
[PDF, 1MB]
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