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Gruppiert nach: Dokumententyp | Veröffentlichungsdatum
Anzahl der Publikationen: 26

Zeitschriftenartikel

Krammer, Christine; Yang, Bishan; Reichl, Sabrina; Besson‐Girard, Simon ORCID logoORCID: https://orcid.org/0000-0003-1194-5256; Ji, Hao; Bolini, Verena; Schulte, Corinna; Noels, Heidi; Schlepckow, Kai; Jocher, Georg; Werner, Georg; Willem, Michael; El Bounkari, Omar ORCID logoORCID: https://orcid.org/0000-0002-3051-2096; Kapurniotu, Aphrodite ORCID logoORCID: https://orcid.org/0000-0001-6124-7232; Gokce, Ozgun; Weber, Christian; Mohanta, Sarajo ORCID logoORCID: https://orcid.org/0000-0001-6144-4092 und Bernhagen, Jürgen ORCID logoORCID: https://orcid.org/0000-0003-2996-2652 (2023): Pathways linking aging and atheroprotection in Mif‐deficient atherosclerotic mice. In: The FASEB Journal, Bd. 37, Nr. 3 [PDF, 12MB]

Blume, Tanja; Deussing, Maximilian; Biechele, Gloria; Peters, Finn; Zott, Benedikt; Schmidt, Claudio; Franzmeier, Nicolai; Wind, Karin; Eckenweber, Florian; Sacher, Christian; Shi, Yuan; Ochs, Katharina; Kleinberger, Gernot; Xiang, Xianyuan; Focke, Carola; Lindner, Simon; Gildehaus, Franz-Josef; Beyer, Leonie; von Ungern-Sternberg, Barbara; Bartenstein, Peter; Baumann, Karlheinz; Adelsberger, Helmuth; Rominger, Axel; Cumming, Paul; Willem, Michael; Dorostkar, Mario M.; Herms, Jochen und Brendel, Matthias (30. März 2022): Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition. In: Frontiers in Aging Neuroscience, Bd. 14 [PDF, 7MB]

Vitale, Paola; Salgueiro-Pereira, Ana Rita; Lupascu, Carmen Alina; Willem, Michael; Migliore, Rosanna; Migliore, Michele und Marie, Helene (11. Juni 2021): Analysis of Age-Dependent Alterations in Excitability Properties of CA1 Pyramidal Neurons in an APPPS1 Model of Alzheimer’s Disease. In: Frontiers in Aging Neuroscience, Bd. 13, 668948 [PDF, 4MB]

Xiang, Xianyuan; Wind, Karin; Wiedemann, Thomas; Blume, Tanja; Shi, Yuan; Briel, Nils; Beyer, Leonie; Biechele, Gloria; Eckenweber, Florian; Zatcepin, Artem; Lammich, Sven; Ribicic, Sara; Tahirovic, Sabina; Willem, Michael; Deussing, Maximilian; Palleis, Carla; Rauchmann, Boris-Stephan; Gildehaus, Franz-Josef; Lindner, Simon; Spitz, Charlotte; Franzmeier, Nicolai; Baumann, Karlheinz; Rominger, Axel; Bartenstein, Peter; Ziegler, Sibylle; Drzezga, Alexander; Respondek, Gesine; Buerger, Katharina; Perneczky, Robert; Levin, Johannes; Hoeglinger, Guenter U.; Herms, Jochen; Haass, Christian und Brendel, Matthias (2021): Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases. In: Science Translational Medicine, Bd. 13, Nr. 615, eabe5640

Mensch, Maria; Dunot, Jade; Yishan, Sandy M.; Harris, Samuel S.; Blistein, Aline; Avdiu, Alban; Pousinha, Paula A.; Giudici, Camilla; Busche, Marc Aurel; Jedlicka, Peter; Willem, Michael und Marie, Helene (2021): A eta-alpha and A eta-beta peptides impair LTP ex vivo within the low nanomolar range and impact neuronal activity in vivo. In: Alzheimers Research & Therapy, Bd. 13, Nr. 1, 125

Hampel, Harald; Vassar, Robert; De Strooper, Bart; Hardy, John; Willem, Michael; Singh, Neeraj; Zhou, John; Yan, Riqiang; Vanmechelen, Eugeen; De Vos, Ann; Nistico, Robert; Corbo, Massimo; Imbimbo, Bruno Pietro; Streffer, Johannes; Voytyuk, Iryna; Timmers, Maarten; Monfared, Amir Abbas Tahami; Irizarry, Michael; Albala, Bruce; Koyama, Akihiko; Watanabe, Naoto; Kimura, Teiji; Yarenis, Lisa; Lista, Simone; Kramer, Lynn und Vergallo, Andrea (2021): The beta-Secretase BACE1 in Alzheimer's Disease. In: Biological Psychiatry, Bd. 89, Nr. 8: S. 745-756

Biechele, Gloria; Wind, Karin; Blume, Tanja; Sacher, Christian; Beyer, Leonie; Eckenweber, Florian; Franzmeier, Nicolai; Ewers, Michael; Zott, Benedikt; Lindner, Simon; Gildehaus, Franz-Josef; Ungern-Sternberg, Barbara von; Tahirovic, Sabina; Willem, Michael; Bartenstein, Peter; Cumming, Paul; Rominger, Axel; Herms, Jochen und Brendel, Matthias (2021): Microglial activation in the right amygdala-entorhinal-hippocampal complex is associated with preserved spatial learning in mice. In: Neuroimage, Bd. 230, 117707

Biechele, Gloria; Blume, Tanja; Deussing, Maximilian; Zott, Benedikt; Shi, Yuan; Xiang, Xianyuan; Franzmeier, Nicolai; Kleinberger, Gernot; Peters, Finn; Ochs, Katharina; Focke, Carola; Sacher, Christian; Wind, Karin; Schmidt, Claudio; Lindner, Simon; Gildehaus, Franz-Josef; Eckenweber, Florian; Beyer, Leonie; Ungern-Sternberg, Barbara von; Bartenstein, Peter; Baumann, Karlheinz; Dorostkar, Mario M.; Rominger, Axel; Cumming, Paul; Willem, Michael; Adelsberger, Helmuth; Herms, Jochen und Brendel, Matthias (2021): Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation. In: Theranostics, Bd. 11, Nr. 18: S. 8964-8976

Schlepckow, Kai; Monroe, Kathryn M.; Kleinberger, Gernot; Cantuti‐Castelvetri, Ludovico; Parhizkar, Samira; Xia, Dan; Willem, Michael; Werner, Georg; Pettkus, Nadine; Brunner, Bettina; Sülzen, Alice; Nuscher, Brigitte; Hampel, Heike; Xiang, Xianyuan; Feederle, Regina; Tahirovic, Sabina; Park, Joshua I.; Prorok, Rachel; Mahon, Cathal; Liang, Chun‐Chi; Shi, Ju; Kim, Do Jin; Sabelström, Hanna; Huang, Fen; Paolo, Gilbert di; Simons, Mikael; Lewcock, Joseph W. und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (7. April 2020): Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region. , Bd. 12, Nr. 4, e11227 [PDF, 4MB]

Monasor, Laura Sebastian; Müller, Stephan A.; Colombo, Alessio Vittorio; Tanrioever, Gaye; König, Jasmin; Roth, Stefan; Liesz, Arthur; Berghofer, Anna; Piechotta, Anke; Prestel, Matthias; Saito, Takashi; Saido, Takaomi C.; Herms, Jochen; Willem, Michael; Haass, Christian; Lichtenthaler, Stefan F. und Tahirovic, Sabina (2020): Fibrillar Aβ (beta) triggers microglial proteome alterations and dysfunction in Alzheimer mouse models. In: eLife, Bd. 9, e54083 [PDF, 14MB]

Sacher, Christian; Blume, Tanja; Beyer, Leonie; Biechele, Gloria; Sauerbeck, Julia; Eckenweber, Florian; Deussing, Maximilian; Focke, Carola; Parhizkar, Samira; Lindner, Simon; Gildehaus, Franz-Josef; Ungern-Sternberg, Barbara von; Baumann, Karlheinz; Tahirovic, Sabina; Kleinberger, Gernot; Willem, Michael; Haass, Christian; Bartenstein, Peter; Cumming, Paul; Rominger, Axel; Herms, Jochen und Brendel, Matthias (2020): Asymmetry of Fibrillar Plaque Burden in Amyloid Mouse Models. In: Journal of Nuclear Medicine, Bd. 61, Nr. 12

Mohammadi, Behnam; Linsenmeier, Luise; Shafiq, Mohsin; Puig, Berta; Galliciotti, Giovanna; Giudici, Camilla; Willem, Michael; Eden, Thomas; Koch-Nolte, Friedrich; Lin, Yu-Hsuan; Tatzelt, Jörg; Glatzel, Markus und Altmeppen, Hermann C. (2020): Transgenic Overexpression of the Disordered Prion Protein N1 Fragment in Mice Does Not Protect Against Neurodegenerative Diseases Due to Impaired ER Translocation. In: Molecular Neurobiology, Bd. 57, Nr. 6: S. 2812-2829

Vnencak, Matej; Schoelvinck, Marieke L.; Schwarzacher, Stephan W.; Deller, Thomas; Willem, Michael und Jedlicka, Peter (2019): Lack of -amyloid cleaving enzyme-1 (BACE1) impairs long-term synaptic plasticity but enhances granule cell excitability and oscillatory activity in the dentate gyrus in vivo. In: Brain Structure & Function, Bd. 224, Nr. 3: S. 1279-1290

Parhizkar, Samira; Arzberger, Thomas; Brendel, Matthias; Kleinberger, Gernot; Deussing, Maximilian; Focke, Carola; Nuscher, Brigitte; Xiong, Monica; Ghasemigharagoz, Alireza; Katzmarski, Natalie; Krasemann, Susanne; Lichtenthaler, Stefan F.; Müller, Stephan A.; Colombo, Alessio; Monasor, Laura Sebastian; Tahirovic, Sabina; Herms, Jochen; Willem, Michael; Pettkus, Nadine; Butovsky, Oleg; Bartenstein, Peter; Edbauer, Dieter; Rominger, Axel; Ertuerk, Ali; Grathwohl, Stefan A.; Neher, Jonas J.; Holtzman, David M.; Meyer-Luehmann, Melanie und Haass, Christian (2019): Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE. In: Nature Neuroscience, Bd. 22, Nr. 2

Gomes, Luis Aragao; Hipp, Silvia Andrea; Upadhaya, Ajeet Rijal; Balakrishnan, Karthikeyan; Ospitalieri, Simona; Koper, Marta J.; Largo-Barrientos, Pablo; Uytterhoeven, Valerie; Reichwald, Julia; Rabe, Sabine; Vandenberghe, Rik; Arnim, Christine A. F. von; Tousseyn, Thomas; Feederle, Regina; Giudici, Camilla; Willem, Michael; Staufenbiel, Matthias und Thal, Dietmar Rudolf (2019): A beta-induced acceleration of Alzheimer-related tau-pathology spreading and its association with prion protein. In: Acta Neuropathologica, Bd. 138, Nr. 6: S. 913-941

Voeglein, Jonathan; Willem, Michael; Trambauer, Johannes; Schönecker, Sonja; Dieterich, Marianne; Biskup, Saskia; Giudici, Camilla; Utz, Kathrin; Oberstein, Timo; Brendel, Matthias; Rominger, Axel; Danek, Adrian; Steiner, Harald; Haass, Christian und Levin, Johannes (2019): Identification of a rare presenilin 1 single amino acid deletion mutation (F175del) with unusual amyloid-beta processing effects. In: Neurobiology of Aging, Bd. 84

Hong, Wei; Wang, Zemin; Liu, Wen; O'Malley, Tiernan T.; Jin, Ming; Willem, Michael; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Frosch, Matthew P. und Walsh, Dominic M. (2018): Diffusible, highly bioactive oligomers represent a critical minority of soluble A beta in Alzheimer's disease brain. In: Acta Neuropathologica, Bd. 136, Nr. 1: S. 19-40

Brendel, Matthias; Jaworska, Anna; Overhoff, Felix; Blume, Tanja; Probst, Federico; Gildehaus, Franz-Josef; Bartenstein, Peter; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Bohrmann, Bernd; Herms, Jochen; Willem, Michael und Rominger, Axel (2018): Efficacy of chronic BACE1 inhibition in PS2APP mice depends on the regional A beta deposition rate and plaque burden at treatment initiation. In: Theranostics, Bd. 8, Nr. 18: S. 4957-4968 [PDF, 3MB]

Krämer, Lara Maria; Brettschneider, Johannes; Lennerz, Jochen K.; Walcher, Daniel; Fang, Lubin; Rosenbohm, Angela; Balakrishnan, Karthikeyan; Benckendorff, Julian; Moller, Peter; Just, Steffen; Willem, Michael; Ludolph, Albert C. und Thal, Dietmar Rudolf (2018): Amyloid precursor protein-fragments-containing inclusions in cardiomyocytes with basophilic degeneration and its association with cerebral amyloid angiopathy and myocardial fibrosis. In: Scientific Reports, Bd. 8, 16594 (2018): S. 1-14 [PDF, 5MB]

Pousinha, Paula A.; Mouska, Xavier; Raymond, Elisabeth F.; Gwizdek, Carole; Dhib, Gihen; Poupon, Gwenola; Zaragosi, Laure-Emmanuelle; Giudici, Camilla; Bethus, Ingrid; Pacary, Emilie; Willem, Michael und Marie, Helene (2017): Physiological and pathophysiological control of synaptic GluN2B-NMDA receptors by the C-terminal domain of amyloid precursor protein. In: Elife, Bd. 6, e25659 [PDF, 4MB]

Seipold, Lisa; Damme, Markus; Prox, Johannes; Rabe, Björn; Kasparek, Petr; Sedlacek, Radislav; Altmeppen, Hermann; Willem, Michael; Boland, Barry; Glatzel, Markus und Saftig, Paul (2017): Tetraspanin 3: A central endocytic membrane component regulating the expression of ADAM10, presenilin and the amyloid precursor protein. In: Biochimica et Biophysica Acta-Molecular Cell Research, Bd. 1864, Nr. 1: S. 217-230

Daria, Anna; Colombo, Alessio; Llovera, Gemma; Hampel, Heike; Willem, Michael; Liesz, Arthur; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 und Tahirovic, Sabina (2017): Young microglia restore amyloid plaque clearance of aged microglia. In: Embo Journal, Bd. 36, Nr. 5: S. 583-603

Willem, Michael (2016): Proteolytic processing of Neuregulin-1. In: Brain Research Bulletin, Bd. 126: S. 178-182

Fleck, Daniel; Voss, Matthias; Brankatschk, Ben; Giudici, Camilla; Hampel, Heike; Schwenk, Benjamin; Edbauer, Dieter; Fukumori, Akio; Steiner, Harald; Kremmer, Elisabeth; Haug-Kröper, Martina; Rossner, Moritz J.; Fluhrer, Regina; Willem, Michael und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2016): Proteolytic Processing of Neuregulin 1 Type III by Three Intramembrane-cleaving Proteases. In: Journal of Biological Chemistry, Bd. 291, Nr. 1: S. 318-333

Ben Halima, Saoussen; Mishra, Sabyashachi; Raja, K. Muruga Poopathi; Willem, Michael; Baici, Antonio; Simons, Kai; Bruestle, Oliver; Koch, Philipp; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Caflisch, Amedeo und Rajendran, Lawrence (2016): Specific Inhibition of beta-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein. In: Cell Reports, Bd. 14, Nr. 9: S. 2127-2141 [PDF, 13MB]

Itoh, Naohiro; Okochi, Masayasu; Tagami, Shinji; Nishitomi, Kouhei; Nakayama, Taisuke; Yanagida, Kanta; Fukumori, Akio; Jiang, Jingwei; Mori, Kohji; Hosono, Motoko; Kikuchi, Jyunko; Nakano, Yuko; Takinami, Yoshihiko; Dohi, Keiji; Nishigaki, Atsuko; Takemoto, Hiroshi; Minagawa, Kazuyuki; Katoh, Takaaki; Willem, Michael; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Morihara, Takashi; Tanaka, Toshihisa; Kudo, Takashi; Hasegawa, Hiroshi; Nishimura, Masaki; Sakaguchi, Gaku; Kato, Akira und Takeda, Masatoshi (2009): Destruxin E Decreases Beta-Amyloid Generation by Reducing Colocalization of Beta-Amyloid-Cleaving Enzyme 1 and Beta-Amyloid Protein Precursor. In: Neurodegenerative Diseases, Nr. 5-6: S. 230-239 [PDF, 556kB]

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