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Horizon 2020 > RIA - Research and Innovation action > SVDs-at-target - Small Vessel Diseases from a therapeutic perspective: Targets for intervention. Affected pathways and mechanistic exploitation for prevention of stroke dementia

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Number of items at this level: 28.

2020

Asare, Y.; Campbell-James, T. A.; Bokov, Y.; Yu, L. L.; Prestel, M.; El Bounkari, O.; Roth, S.; Megens, Remco; Straub, T.; Thomas, K.; Yan, G.; Schneider, M.; Ziesch, N.; Tiedt, Steffen; Silvestre-Roig, Carlos; Braster, Quinte; Huang, Y.; Schneider, M.; Malik, Rainer; Haffner, Christof; Liesz, Arthur; Soehnlein, Oliver; Bernhagen, Jürgen; Dichgans, Martin (17. June 2020): Histone Deacetylase 9 Activates IKK to Regulate Atherosclerotic Plaque Vulnerability. In: Circulation Research [PDF, 18MB]

Georgakis, Marios K.; Malik, Rainer; Anderson, Christopher D.; Parhofer, Klaus G.; Hopewell, Jemma C.; Dichgans, Martin (1. February 2020): Genetic determinants of blood lipids and cerebral small vessel disease: role of high-density lipoprotein cholesterol. In: Brain, Vol. 143, No. 2: pp. 597-610 [PDF, 1MB]

Georgakis, Marios K.; Malik, Rainer; Gillor, D.; Franceschini, Nora; Sudlow, Cathie L. M.; Dichgans, Martin (17. June 2020): Interleukin-6 Signaling Effects on Ischemic Stroke and Other Cardiovascular Outcomes: A Mendelian Randomization Study. In: Circulation: Genomic and Precision Medicine, Vol. 13, No. 3 [PDF, 273kB]

2019

Abraham, G.; Malik, Rainer; Yonova-Doing, E.; Salim, Agus; Wang, T.; Danesh, John; Butterworth, Adam S.; Howson, Joanna M. M.; Inouye, M.; Dichgans, Martin (20. December 2019): Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke. In: Nature Communications, 5819 [PDF, 1MB]

Chauhan, Ganesh; Malik, Rainer; Dichgans, Martin (16. January 2019): Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. In: Neurology, Vol. 92, No. 5, e486-e503 [PDF, 372kB]

Dichgans, Martin (1. March 2019): Dementia risk after transient ischaemic attack and stroke. In: The Lancet Neurology, Vol. 18, No. 3: pp. 223-225 [PDF, 54kB]

Dichgans, Martin; Pulit, Sara L.; Rosand, Jonathan (1. June 2019): Stroke genetics: discovery, biology, and clinical applications. In: The Lancet Neurology, Vol. 18, No. 6: pp. 587-599 [PDF, 2MB]

Georgakis, Marios K.; Duering, Marco; Wardlaw, Joanna M.; Dichgans, Martin (19. March 2019): WMH and long-term outcomes in ischemic stroke. A systematic review and meta-analysis. In: Neurology, Vol. 92, No. 12, e1298-e1308 [PDF, 1MB]

Georgakis, Marios K.; Gill, Dipender; Rannikmae, Kristiina; Traylor, Matthew; Anderson, Christopher D.; Lee, Jin-Moo; Kamatani, Yoichiro; Hopewell, Jemma C.; Worrall, Bradford B.; Bernhagen, Jürgen; Sudlow, Cathie L. M.; Malik, Rainer; Dichgans, Martin (January 2019): Genetically Determined Levels of Circulating Cytokines and Risk of Stroke. Role of Monocyte Chemoattractant Protein-1. In: Circulation, Vol. 139, No. 2 [PDF, 772kB]

Georgakis, Marios K.; Malik, Rainer; Dichgans, Martin (27. September 2019): Circulating Monocyte Chemoattractant Protein-1 and Risk of Stroke. Meta-Analysis of Population-Based Studies Involving 17 180 Individuals. In: Circulation Research, Vol. 125, No. 8 [PDF, 500kB]

Sun, D.; Tiedt, S.; Yu, B.; Jian, X.; Gottesman, Rebecca F.; Mosley, Thomas H.; Boerwinkle, Eric; Dichgans, Martin; Fornage, Myriam (16. April 2019): A prospective study of serum metabolites and risk of ischemic stroke. In: Neurology, Vol. 92, No. 16, e1890-e1898 [PDF, 194kB]

Telgte, Annemieke ter; Wiegertjes, Kim; Gesierich, Benno; Marques, Jose P.; Huebner, M.; Klerk, J. J. de; Schreuder, F. H.; Araque Caballero, Miguel Angel; Kuijf, H. J.; Norris, David G.; Klijn, Catharina J. M.; Dichgans, Martin; Tuladhar, Anil Man; Duering, Marco; de Leeuw, Frank-Erik (1. October 2019): The contribution of acute infarcts to cerebral small vessel disease progression. In: Annals of Neurology, Vol. 86, No. 4: pp. 582-592 [PDF, 1MB]

Wollenweber, Frank A.; Opherk, Christian; Zedde, Marialuisa; Catak, Cihan; Malik, Rainer; Duering, Marco; Konieczny, Marek J.; Pascarella, R.; Samões, R.; Correia, M.; Martí-Fàbregas, J.; Linn, Jennifer; Dichgans, Martin (19. February 2019): Prognostic relevance of cortical superficial siderosis in cerebral amyloid angiopathy. In: Neurology, Vol. 92, No. 8, e792-e801 [PDF, 536kB]

2018

Duering, Marco; Finsterwalder, Sofia; Baykara, Ebru; Tuladhar, Anil Man; Gesierich, Benno; Konieczny, Marek J.; Malik, Rainer; Franzmeier, Nicolai; Ewers, Michael; Jouvent, Eric; Biessels, Geert Jan; Schmidt, Reinhold; Leeuw, Frank-Erik de; Pasternak, Ofer; Dichgans, Martin (2018): Free water determines diffusion alterations and clinical status in cerebral small vessel disease. In: Alzheimers & Dementia, Vol. 14, No. 6: pp. 764-774

Malik, Rainer; Dichgans, Martin (2018): Challenges and opportunities in stroke genetics. In: Cardiovascular Research, Vol. 114, No. 9: pp. 1226-1240

Rutten-Jacobs, Loes C. A.; Tozer, Daniel J.; Düring, Marco; Malik, Rainer; Dichgans, Martin; Markus, Hugh S.; Traylor, Matthew (2018): Genetic Study of White Matter Integrity in UK Biobank (N=8448) and the Overlap With Stroke, Depression, and Dementia. In: Stroke, Vol. 49, No. 6: pp. 1340-1347 [PDF, 1MB]

Rutten-Jacobs, Loes Ca; Larsson, Susanna C.; Malik, Rainer; Rannikmae, Kristiina; Sudlow, Cathie L.; Dichgans, Martin; Markus, Hugh S.; Traylor, Matthew (2018): Genetic risk, incident stroke, and the benefits of adhering to a healthy lifestyle: cohort study of 306 473 UK Biobank participants. In: BMJ-British Medical Journal, Vol. 363, k4168 [PDF, 420kB]

Tiedt, Steffen; Dichgans, Martin (2018): Role of Non-Coding RNAs in Stroke. In: Stroke, Vol. 49, No. 12: pp. 3098-3106 [PDF, 2MB]

Tiedt, Steffen; Duering, Marco; Barro, Christian; Kaya, Asli Gizem; Böck, Julia; Bode, Felix J.; Klein, Matthias; Dorn, Franziska; Gesierich, Benno; Kellert, Lars; Ertl-Wagner, Birgit; Goertler, Michael W.; Petzold, Gabor C.; Kuhle, Jens; Wollenweber, Frank A.; Peters, Nils; Dichgans, Martin (2018): Serum neurofilament light A biomarker of neuroaxonal injury after ischemic stroke. In: Neurology, Vol. 91, No. 14, E1338-E1347 [PDF, 659kB]

Zellner, Andreas; Scharrer, Eva; Arzberger, Thomas; Oka, Chio; Domenga-Denier, Valerie; Joutel, Anne; Lichtenthaler, Stefan F.; Müller, Stephan A.; Dichgans, Martin; Haffner, Christof (2018): CADASIL brain vessels show a HTRA1 loss-of-function profile. In: Acta Neuropathologica, Vol. 136, No. 1: pp. 111-125

Zietemann, Vera; Georgakis, Marios K.; Dondaine, Thibaut; Müller, Claudia; Mendyk, Anne-Marie; Kopczak, Anna; Henon, Hilde; Bombois, Stephanie; Wollenweber, Frank Arne; Bordet, Regis; Dichgans, Martin (2018): Early MoCA predicts long-term cognitive and functional outcome and mortality after stroke. In: Neurology, Vol. 91, No. 20, E1838-E1850 [PDF, 738kB]

2017

Dichgans, Martin; Leys, Didier (2017): Vascular Cognitive Impairment. In: Circulation Research, Vol. 120, No. 3: pp. 573-591 [PDF, 1MB]

Lubitz, Steven A.; Parsons, Owen E.; Anderson, Christopher D.; Benjamin, Emelia J.; Malik, Rainer; Weng, Lu-Chen; Dichgans, Martin; Sudlow, Cathie L.; Rothwell, Peter M.; Rosand, Jonathan; Ellinor, Patrick T.; Markus, Hugh S.; Traylor, Matthew (2017): Atrial Fibrillation Genetic Risk and Ischemic Stroke Mechanisms. In: Stroke, Vol. 48, No. 6: pp. 1451-1456

Rannikmäe, Kristiina; Sivakumaran, Vhinoth; Millar, Henry; Malik, Rainer; Anderson, Christopher D.; Chong, Mike; Dave, Tushar; Falcone, Guido J.; Fernandez-Cadenas, Israel; Jimenez-Conde, Jordi; Lindgren, Arne; Montaner, Joan; O'Donnell, Martin; Pare, Guillaume; Radmanesh, Farid; Rost, Natalia S.; Slowik, Agnieszka; Söderholm, Martin; Traylor, Matthew; Pulit, Sara L.; Seshadri, Sudha; Worrall, Brad B.; Woo, Daniel; Markus, Hugh S.; Mitchell, Braxton D.; Dichgans, Martin; Rosand, Jonathan; Sudlow, Cathie L. M. (2017): COL4A2 is associated with lacunar ischemic stroke and deep ICH Meta-analyses among 21,500 cases and 40,600 controls. In: Neurology, Vol. 89, No. 17: pp. 1829-1839 [PDF, 720kB]

Tiedt, Steffen; Prestel, Matthias; Malik, Rainer; Schieferdecker, Nicola; Düring, Marco; Kautzky, Veronika; Stoycheva, Ivelina; Boeck, Julia; Northoff, Bernd H.; Klein, Matthias; Dorn, Franziska; Krohn, Knut; Teupser, Daniel; Liesz, Arthur; Plesnila, Nikolaus; Holdt, Lesca Miriam; Dichgans, Martin (2017): RNA-Seq Identifies Circulating miR-125a-5p, miR-125b-5p, and miR-143-3p as Potential Biomarkers for Acute Ischemic Stroke. In: Circulation Research, Vol. 121, No. 8: pp. 970-980

Traylor, Matthew; Malik, Rainer; Dichgans, Martin (2017): Genetic variation at 16q24.2 is associated with small vessel stroke. In: Annals of Neurology, Vol. 81, No. 3: pp. 383-394 [PDF, 502kB]

2016

Dichgans, Martin; Wardlaw, Joanna; Smith, Eric; Zietemann, Vera; Seshadri, Sudha; Sachdev, Perminder; Biessels, Geert Jan; Fazekas, Franz; Benavente, Oscar; Pantoni, Leonardo; Deeuw, Frankerik de; Norrving, Bo; Matthews, Paul; Chen, Christopher; Mok, Vincent; Duering, Marco; Whiteley, Will; Shuler, Kirsten; Alonso, Alvaro; Black, Sandra E.; Brayne, Carol; Chabriat, Hugues; Cordonnier, Charlotte; Doubal, Fergus; Duzel, Emrah; Ewers, Michael; Frayne, Richard; Hachinski, Vladimir; Ikram, Mohammad Arfan; Jessen, Frank; Jouvent, Eric; Linn, Jennifer; O'Brien, John; Oostenbrugge, Robert van; Malik, Rainer; Mazoyer, Bernard; Schmidt, Reinhold; Sposato, Luciano A.; Stephan, Blossom; Swartz, Richard H.; Vernooij, Meike; Viswanathan, Anand; Werring, David; Abe, Koji; Allan, Louise; Arba, Francesco; Bae, Hee-Joon; Bath, Philip M. W.; Bordet, Regis; Breteler, Monique; Choi, Seong; Deary, Ian; DeCarli, Charles; Ebmeier, Klaus; Feng, Lei; Greenberg, Steven M.; Ihara, Masafumi; Kalaria, Rajesh; Kim, SanYun; Lim, Jae-Sung; Lindley, Richard I.; Mead, Gillian; Murray, Alison; Quinn, Terry; Ritchie, Craig; Sacco, Ralph; Salman, Rustam Al-Shahi; Sprigg, Nikola; Sudlow, Cathie; Thomas, Alan; Boxtel, Martin van; Grond, Jeroen van der; Lugt, Aad van der; Yang, Yuan-Han (2016): METACOHORTS for the study of vascular disease and its contribution to cognitive decline and neurodegeneration: An initiative of the Joint Programme for Neurodegenerative Disease Research. In: Alzheimers & Dementia, Vol. 12, No. 12: pp. 1235-1249 [PDF, 979kB]

Jouvent, Eric; Duchesnay, Edouard; Hadj-Selem, Foued; Guio, François de; Mangin, Jean-François; Hervé, Dominique; Duering, Marco; Ropele, Stefan; Schmidt, Reinhold; Dichgans, Martin; Chabriat, Hugues (2016): Prediction of 3-year clinical course in CADASIL. In: Neurology, Vol. 87, No. 17: pp. 1787-1795 [PDF, 850kB]

This list was generated on Mon Nov 23 18:19:52 2020 CET.