Chemistry and Pharmacy > GeneCenter

2022

Stafford, Che A.; Gassauer, Alicia-Marie; Oliveira Mann, Carina C. de; Tanzer, Maria C. ORCID: 0000-0002-4657-9869; Fessler, Evelyn; Wefers, Benedikt ORCID: 0000-0002-2492-9389; Nagl, Dennis; Kuut, Gunnar; Sulek, Karolina; Vasilopoulou, Catherine; Schwojer, Sophia J. ORCID: 0000-0002-1747-4144; Wiest, Andreas ORCID: 0000-0003-2525-6304; Pfautsch, Marie K.; Wurst, Wolfgang ORCID: 0000-0003-4422-7410; Yabal, Monica ORCID: 0000-0003-3495-7671; Fröhlich, Thomas ORCID: 0000-0002-4709-3211; Mann, Matthias ORCID: 0000-0003-1292-4799; Gisch, Nicolas ORCID: 0000-0003-3260-5269; Jae, Lucas T. ORCID: 0000-0002-3531-1760; Hornung, Veit ORCID: 0000-0002-4150-194X (2022): Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation. In: Nature [Forthcoming]

2021

Tahk, Siret; Vick, Binje; Hiller, Björn; Schmitt, Saskia; Marcinek, Anetta; Perini, Enrico D.; Leutbecher, Alexandra; Augsberger, Christian; Reischer, Anna; Tast, Benjamin; Humpe, Andreas; Jeremias, Irmela; Subklewe, Marion; Fenn, Nadja C.; Hopfner, Karl-Peter ORCID: 0000-0002-4528-8357 (2021): SIRPα-αCD123 fusion antibodies targeting CD123 in conjunction with CD47 blockade enhance the clearance of AML-initiating cells. In: Journal of hematology & oncology, Vol. 14, 155 [PDF, 3MB]

2020

Ghodgaonkar-Steger, Medini; Potocnjak, Mia; Zimniak, Tomasz; Fischböck-Halwachs, Josef; Solis-Mezarino, Victor; Singh, Sylvia; Speljko, Tea; Hagemann, Götz; Drexler, David Jan; Witte, Gregor; Herzog, Franz ORCID: 0000-0001-8270-1449 (2020): C-Terminal Motifs of the MTW1 Complex Cooperatively Stabilize Outer Kinetochore Assembly in Budding Yeast. In: Cell reports, Vol. 32, No. 13, 108190 [PDF, 5MB]

Hedegger, Kathrin; Algül, Hana; Lesina, Marina; Blutke, Andreas; Schmid, Roland M.; Schneider, Marlon R.; Dahlhoff, Maik (2020): Unraveling ERBB network dynamics upon betacellulin signaling in pancreatic ductal adenocarcinoma in mice. In: Molecular Oncology, Vol. 14, No. 8: pp. 1653-1669 [PDF, 2MB]

Hopfner, Karl-Peter ORCID: 0000-0002-4528-8357; Hornung, Veit ORCID: 0000-0002-4150-194X (18. May 2020): Molecular mechanisms and cellular functions of cGAS-STING signalling. In: Nature Reviews Molecular Cell Biology, Vol. 21: pp. 501-521 [PDF, 13MB]

Jungblut, Anna; Hopfner, Karl-Peter ORCID: 0000-0002-4528-8357; Eustermann, Sebastian (6. August 2020): Megadalton chromatin remodelers: Common principles for versatile functions. In: Current Opinion in Structural Biology, Vol. 64, 32771531: pp. 134-144 [PDF, 3MB]

2019

Fischböck-Halwachs, Josef; Singh, Sylvia; Potocnjak, Mia; Hagemann, Götz; Solis-Mezarino, Victor; Woike, Stephan; Ghodgaonkar-Steger, Medini; Weissmann, Florian; Gallego, Laura D.; Rojas, Julie; Andreani, Jessica; Köhler, Alwin; Herzog, Franz ORCID: 0000-0001-8270-1449 (2019): The COMA complex interacts with Cse4 and positions Sli15/Ipl1 at the budding yeast inner kinetochore. In: eLife, Vol. 8, e42879 [PDF, 6MB]

Hemmer, Charlotte M.; Wierer, Michael; Schachtrup, Kristina; Downes, Michael; Hübner, Norbert; Evans, Ronald M.; Uhlenhaut, N. Henriette ORCID: 0000-0002-4220-4779 (18. January 2019): E47 modulates hepatic glucocorticoid action. In: Nature Communications, Vol. 10, No. 306: pp. 1-13 [PDF, 1MB]

2018

Chauhan, Dhruv; Bartok, Eva; Gaidt, Moritz M.; Bock, Florian J.; Herrmann, Jennifer; Seeger, Jens M.; Broz, Petr; Beckmann, Roland; Kashkar, Hamid; Tait, Stephen W. G.; Müller, Rolf; Hornung, Veit (2018): BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1beta Maturation in Macrophages. In: Cell Reports, Vol. 25, No. 9, P2354-2368.E5

Jangra, Rohit K.; Herbert, Andrew S.; Li, Rong; Jae, Lucas T.; Kleinfelter, Lara M.; Slough, Megan M.; Barker, Sarah L.; Guardado-Calvo, Pablo; Roman-Sosa, Gleyder; Dieterle, M. Eugenia; Kuehne, Ana I.; Muena, Nicolas A.; Wirchnianski, Ariel S.; Nyakatura, Elisabeth K.; Fels, J. Maximilian; Ng, Melinda; Mittler, Eva; Pan, James; Bharrhan, Sushma; Wec, Anna Z.; Lai, Jonathan R.; Sidhu, Sachdev S.; Tischler, Nicole D.; Rey, Felix A.; Moffat, Jason; Brummelkamp, Thijn R.; Wang, Zhongde; Dye, John M.; Chandran, Kartik (2018): Protocadherin-1 is essential for cell entry by New World hantaviruses. In: Nature, Vol. 563, No. 7732: pp. 559-563

2017

Mosalaganti, Shyamal; Keller, Jenny; Altenfeld, Anika; Winzker, Michael; Rombaut, Pascaline; Saur, Michael; Petrovic, Arsen; Wehenkel, Annemarie; Wohlgemuth, Sabine; Müller, Franziska; Maffini, Stefano; Bange, Tanja; Herzog, Franz ORCID: 0000-0001-8270-1449; Waldmann, Herbert; Raunser, Stefan; Musacchio, Andrea (2017): Structure of the RZZ complex and molecular basis of its interaction with Spindly. In: Journal of cell biology, Vol. 216, No. 4: pp. 961-981 [PDF, 4MB]

Solis-Mezarino, Victor; Herzog, Franz ORCID: 0000-0001-8270-1449 (2017): compleXView: a server for the interpretation of protein abundance and connectivity information to identify protein complexes. In: Nucleic acids research, Vol. 45, No. W1: W276-W284 [PDF, 4MB]

2016

Gallego, Laura D.; Ghodgaonkar Steger, Medini; Polyansky, Anton A.; Schubert, Tobias; Zagrovic, Bojan; Zheng, Ning; Clausen, Tim; Herzog, Franz ORCID: 0000-0001-8270-1449; Köhler, Alwin (2016): Structural mechanism for the recognition and ubiquitination of a single nucleosome residue by Rad6-Bre1. In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, No. 38: pp. 10553-10558 [PDF, 1MB]

Heuck, Alexander; Schitter-Sollner, Sonja; Suskiewicz, Marcin Józef; Kurzbauer, Robert; Kley, Juliane; Schleiffer, Alexander; Rombaut, Pascaline; Herzog, Franz ORCID: 0000-0001-8270-1449; Clausen, Tim (2016): Structural basis for the disaggregase activity and regulation of Hsp104. In: eLife, Vol. 5, e21516 [PDF, 5MB]

Liu, Yahui; Petrovic, Arsen; Rombaut, Pascaline; Mosalaganti, Shyamal; Keller, Jenny; Raunser, Stefan; Herzog, Franz ORCID: 0000-0001-8270-1449; Musacchio, Andrea (2016): Insights from the reconstitution of the divergent outer kinetochore of Drosophila melanogaster. In: Open biology, Vol. 6, No. 2, 150236 [PDF, 3MB]

Petrovic, Arsen; Keller, Jenny; Liu, Yahui; Overlack, Katharina; John, Juliane; Dimitrova, Yoana N.; Jenni, Simon; van Gerwen, Suzan; Stege, Patricia; Wohlgemuth, Sabine; Rombaut, Pascaline; Herzog, Franz ORCID: 0000-0001-8270-1449; Harrison, Stephen C.; Vetter, Ingrid R.; Musacchio, Andrea (2016): Structure of the MIS12 Complex and Molecular Basis of Its Interaction with CENP-C at Human Kinetochores. In: Cell, Vol. 167, No. 4, e15: pp. 1028-1040 [PDF, 6MB]

Schmidtmann, Elisabeth; Anton, Tobias; Rombaut, Pascaline; Herzog, Franz ORCID: 0000-0001-8270-1449; Leonhardt, Heinrich (2016): Determination of local chromatin composition by CasID. In: Nucleus, Vol. 7, No. 5: pp. 476-484 [PDF, 1MB]

Vos, Seychelle M.; Pöllmann, David; Caizzi, Livia; Hofmann, Katharina B.; Rombaut, Pascaline; Zimniak, Tomasz; Herzog, Franz ORCID: 0000-0001-8270-1449; Cramer, Patrick (2016): Architecture and RNA binding of the human negative elongation factor. In: eLife, Vol. 5, e14981 [PDF, 11MB]

Weir, John R.; Faesen, Alex C.; Klare, Kerstin; Petrovic, Arsen; Basilico, Federica; Fischböck, Josef; Pentakota, Satyakrishna; Keller, Jenny; Pesenti, Marion E.; Pan, Dongqing; Vogt, Doro; Wohlgemuth, Sabine; Herzog, Franz ORCID: 0000-0001-8270-1449; Musacchio, Andrea (2016): Insights from biochemical reconstitution into the architecture of human kinetochores. In: Nature, Vol. 537, 7619: pp. 249-253