Improving anti-hypertensive medication taking: The direct and interacting effects of perceived adherence difficulty, adherence knowledge, and commitment to adherence

Xiao, Yazhen; Gessl, Alessandra S. ; Nakata, Cheryl; Spanjol, Jelena ; Crawford, Stephanie Y.; Sharp, Lisa K. und Cui, Anna S. (2. Juli 2024): Improving anti-hypertensive medication taking: The direct and interacting effects of perceived adherence difficulty, adherence knowledge, and commitment to adherence. In: International Journal of Healthcare Management [Forthcoming]

Abstract

Background Non-adherence to anti-hypertensive medications is prevalent, leading to increased hospital costs and preventable deaths and disabilities. Managing patient perceptions of adherence difficulties may be key to improving adherence.

Objective This study examined the potential negative effect of patients’ perceived difficulties with anti-hypertensive medication taking on adherence, along with whether and how that effect could be reduced through patient knowledge of and commitment to adherence.

Method 10,867 adult U.S. residents diagnosed with essential hypertension and prescribed anti-hypertensive medications participated in a cross-sectional online survey using self-reported behaviors and perceptions. Stepwise regressions and mean difference analyses were performed.

Results Perceived adherence difficulty was negatively associated with adherence behaviors (b = -.443, p < .001). This association was reduced by the moderating effects of adherence knowledge (b = .035, p < .001) and commitment to adherence (b = .008, p = .037), and their direct effects on adherence behaviors (b = .075, p < .001; b = .095, p < .001, respectively). Some differences by patient race-ethnicity and income were observed.

Conclusions Perceived adherence difficulty inhibits medication adherence but is countered by adherence knowledge and commitment to adherence. To improve adherence, healthcare strategies should strengthen patient knowledge and commitment by developing medication routines, engaging in self-care and awareness, and receiving tailored counseling on disease management, among others.

• Dokumententyp: Zeitschriftenartikel
• Keywords: Hypertension; Perceived adherence difficulty; Adherence knowledge; Commitment to adherence; Medication adherence; Socioeconomic characteristics.
• Fakultät: Betriebswirtschaft > Institut für Innovation Management
• Themengebiete: 100 Philosophie und Psychologie > 150 Psychologie ; 300 Sozialwissenschaften > 300 Sozialwissenschaft, Soziologie ; 300 Sozialwissenschaften > 330 Wirtschaft ; 300 Sozialwissenschaften > 360 Soziale Probleme, Sozialdienste ; 500 Naturwissenschaften und Mathematik > 500 Naturwissenschaften ; 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit
• ISSN: 2047-9719 (Online)
• Sprache: Englisch

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