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Zeitschriftenartikel
Deiringer, Natalie; Aleshkevich, Sofya; Mueller, Christoph und Friess, Wolfgang
(2022):
Modification of Tubings for Peristaltic Pumping of Biopharmaceutics.
In: Journal of Pharmaceutical Sciences, Bd. 111, Nr. 12: S. 3251-3260
Roche, Aisling; Gentiluomo, Lorenzo; Sibanda, Nicole; Roessner, Dierk; Friess, Wolfgang; Trainoff, Steven P. und Curtis, Robin
(2022):
Towards an improved prediction of concentrated antibody solution viscosity using the Huggins coefficient.
In: Journal of Colloid and Interface Science, Bd. 607, Nr. 2: S. 1813-1824
Nishiumi, Haruka; Deiringer, Natalie; Krause, Nils; Yoneda, Saki; Torisu, Tetsuo; Menzen, Tim; Friess, Wolfgang und Uchiyama, Susumu
(2022):
Utility of Three Flow Imaging Microscopy Instruments for Image Analysis in Evaluating four Types of Subvisible Particle in Biopharmaceuticals.
In: Journal of Pharmaceutical Sciences, Bd. 111, Nr. 11: S. 3017-3028
Bluemel, Oliver; Pavlistic, Andraz; Likozar, Blaz; Rodrigues, Miguel A.; Geraldes, Vitor; Bechtold-Peters, Karoline und Friess, Wolfgang
(2022):
Computational fluid dynamic simulations of temperature, cryoconcentration, and stress time during large-scale freezing and thawing of monoclonal antibody solutions.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 177: S. 107-112
Keil, Tobias W. M.; Deiringer, Natalie; Friess, Wolfgang und Merkel, Olivia M.
(2022):
Evaluation of adsorption of DNA/PEI polyplexes to tubing materials.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 179: S. 58-64
Thaller, Anian; Schmauder, Lukas; Friess, Wolfgang; Winter, Gerhard; Menzen, Tim; Hawe, Andrea und Richter, Klaus
(2022):
SV-AUC as a stability-indicating method for the characterization of mRNA-LNPs.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 182: S. 152-156
Meyer, Robina M.; Aleshkevich, Sofya; Berger, Lukas; Nerkamp, Joerg; Scheler, Stefan und Friess, Wolfgang
(2022):
Characterization of the aggregation propensity of charge variants of recombinant human growth hormone.
In: International Journal of Pharmaceutics, Bd. 621, 121760
Carfagna, Marco; Rosa, Monica; Hawe, Andrea und Friess, Wolfgang
(2022):
Design of freeze-drying cycles: The determination of heat transfer coefficient by using heat flux sensor and MicroFD.
In: International Journal of Pharmaceutics, Bd. 621, 121763
Deiringer, Natalie und Friess, Wolfgang
(2022):
Reaching the breaking point: Effect of tubing characteristics on protein particle formation during peristaltic pumping.
In: International Journal of Pharmaceutics, Bd. 627, 122216
Bluemel, Oliver; Anuschek, Moritz; Buecheler, Jakob W.; Hoelzl, Georg; Bechtold-Peters, Karoline und Friess, Wolfgang
(2022):
The effect of mAb and excipient cryoconcentration on long-term frozen storage stability - Part 1: Higher molecular weight species and subvisible particle formation.
In: International Journal of Pharmaceutics: X, Bd. 4, 100108
Bluemel, Oliver; Buecheler, Jakob W.; Hauptmann, Astrid; Hoelzl, Georg; Bechtold-Peters, Karoline und Friess, Wolfgang
(2022):
The effect of mAb and excipient cryoconcentration on long-term frozen storage stability - part 2: Aggregate formation and oxidation.
In: International Journal of Pharmaceutics: X, Bd. 4, 100109
Bluemel, Oliver; Rodrigues, A. Miguel; Buecheler, W. Jakob; Geraldes, Vitor; Hoelzl, Georg; Hauptmann, Astrid; Bechtold-Peters, Karoline und Friess, Wolfgang
(2022):
Evaluation of Two Novel Scale-Down Devices for Testing Monoclonal Antibody Aggregation During Large-Scale Freezing.
In: Journal of Pharmaceutical Sciences, Bd. 111, Nr. 7: S. 1973-1983
Deiringer, Natalie und Friess, Wolfgang
(2022):
Proteins on the Rack: Mechanistic Studies on Protein Particle Formation During Peristaltic Pumping.
In: Journal of Pharmaceutical Sciences, Bd. 111, Nr. 5: S. 1370-1378
Deiringer, Natalie; Ruediger, Daniel; Luxbacher, Thomas; Zahler, Stefan und Friess, Wolfgang
(2022):
Catching Speedy Gonzales: Driving forces for Protein Film Formation on Silicone Rubber Tubing During Pumping.
In: Journal of Pharmaceutical Sciences, Bd. 111, Nr. 6: S. 1577-1586
Mahapatra, Sujata; Polimeni, Marco; Gentiluomo, Lorenzo; Roessner, Dierk; Friess, Wolfgang; Peters, Guenther H. J.; Streicher, Werner W.; Lund, Mikael und Harris, Pernille
(2021):
Self-Interactions of Two Monoclonal Antibodies: Small-Angle X-ray Scattering, Light Scattering, and Coarse-Grained Modeling.
In: Molecular Pharmaceutics, Bd. 19, Nr. 2: S. 508-519
Domnowski, Martin; Maruno, Takahiro; Enomoto, Kanta; Kummer, Felix; Kulakova, Alina; Harris, Pernille; Uchiyama, Susumu; Jaehrling, Jan und Friess, Wolfgang
(2021):
A Multi-Method Approach to Assess the Self-Interaction Behavior of Infliximab.
In: Journal of Pharmaceutical Sciences, Bd. 110, Nr. 5: S. 1979-1988
Gerckens, Michael; Schorpp, Kenji; Pelizza, Francesco; Woegrath, Melanie; Reichau, Kora; Ma, Huilong; Dworsky, Armando-Marco; Sengupta, Arunima; Stoleriu, Mircea Gabriel; Heinzelmann, Katharina; Merl-Pham, Juliane; Irmler, Martin; Alsafadi, Hani N.; Trenkenschuh, Eduard; Sarnova, Lenka; Jirouskova, Marketa; Friess, Wolfgang; Hauck, Stefanie M.; Beckers, Johannes; Kneidinger, Nikolaus; Behr, Jürgen; Hilgendorff, Anne; Hadian, Kamyar; Lindner, Michael; Koenigshoff, Melanie; Eickelberg, Oliver; Gregor, Martin; Plettenburg, Oliver; Yildirim, Ali Oender und Burgstaller, Gerald
(2021):
Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics.
In: Science Advances, Bd. 7, Nr. 52, eabb3673
Marschall, Christoph; Graf, Gesche; Witt, Madlen; Hauptmeier, Bernhard und Friess, Wolfgang
(2021):
Preparation of high concentration protein powder suspensions by milling of lyophilizates.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 166: S. 75-86
Roche, Aisling; Gentiluomo, Lorenzo; Sibanda, Nicole; Roessner, Dierk; Friess, Wolfgang; Trainoff, Steven P. und Curtis, Robin
(2021):
Towards an improved prediction of concentrated antibody solution viscosity using the Huggins coefficient.
In: Journal of Colloid and Interface Science, Bd. 607: S. 1813-1824
Trenkenschuh, Eduard und Friess, Wolfgang
(2021):
Freeze-thaw stability of aluminum oxide nanoparticles.
In: International Journal of Pharmaceutics, Bd. 606, 120932
Trenkenschuh, Eduard; Richter, Maximilian; Heinrich, Eilien; Koch, Marcus; Fuhrmann, Gregor und Friess, Wolfgang
(2021):
Enhancing the Stabilization Potential of Lyophilization for Extracellular Vesicles.
In: Advanced Healthcare Materials, Bd. 11, Nr. 5, 2100538
Marschall, Christoph; Witt, Madlen; Hauptmeier, Bernhard und Friess, Wolfgang
(2021):
Powder suspensions in non-aqueous vehicles for delivery of therapeutic proteins.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 161: S. 37-49
Martos, Ariadna; Berger, Michelle; Kranz, Wendelin; Spanopoulou, Anna; Menzen, Tim; Friess, Wolfgang; Wuchner, Klaus und Hawe, Andrea
(2020):
Novel High-Throughput Assay for Polysorbate Quantification in Biopharmaceutical Products by Using the Fluorescent Dye DiI.
In: Journal of Pharmaceutical Sciences, Bd. 109, Nr. 1: S. 646-655
Haeuser, Christina; Goldbach, Pierre; Huwyler, Jörg; Friess, Wolfgang und Allmendinger, Andrea
(2020):
Impact of dextran on thermal properties, product quality attributes, and monoclonal antibody stability in freeze-dried formulations.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 147: S. 45-56
Seifert, Ivonne; Bregolin, Alessandro; Fissore, Davide und Friess, Wolfgang
(2020):
Method development and analysis of the water content of the maximally freeze concentrated solution suitable for protein lyophilisation.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 153: S. 36-42
Carfagna, Marco; Rosa, Monica; Lucke, Matthias; Hawe, Andrea und Friess, Wolfgang
(2020):
Heat flux sensor to create a design space for freeze-drying development.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 153: S. 84-94
Traub-Hoffmann, Kerstin; Gegenfurtner, Katrin; Kraft, Kay-Uwe und Friess, Wolfgang
(2020):
Spray congealed solid lipid microparticles as a sustained release delivery system for Gonadorelin [6-D-Phe]: Production, optimization and in vitro release behavior.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 154: S. 18-32
Gentiluomo, Lorenzo; Roessner, Dierk und Friess, Wolfgang
(2020):
Application of machine learning to predict monomer retention of therapeutic proteins after long term storage.
In: International Journal of Pharmaceutics, Bd. 577, 119039
Seifert, Ivonne und Friess, Wolfgang
(2020):
Freeze concentration during freezing: How does the maximally freeze concentrated solution influence protein stability?
In: International Journal of Pharmaceutics, Bd. 589, 119810
Seifert, Ivonne und Friess, Wolfgang
(2020):
Improvement of arginine hydrochloride based antibody lyophilisates.
In: International Journal of Pharmaceutics, Bd. 589, 119859
Helbig, Constanze; Ammann, Gregor; Menzen, Tim; Friess, Wolfgang; Wuchner, Klaus und Hawe, Andrea
(2020):
Backgrounded Membrane Imaging (BMI) for High-Throughput Characterization of Subvisible Particles During Biopharmaceutical Drug Product Development.
In: Journal of Pharmaceutical Sciences, Bd. 109, Nr. 1: S. 264-276
Gentiluomo, Lorenzo; Roessner, Dierk; Streicher, Werner; Mahapatra, Sujata; Harris, Pernille und Friess, Wolfgang
(2020):
Characterization of Native Reversible Self-Association of a Monoclonal Antibody Mediated by Fab-Fab Interaction.
In: Journal of Pharmaceutical Sciences, Bd. 109, Nr. 1: S. 443-451
Haeuser, Christina; Goldbach, Pierre; Huwyler, Jörg; Friess, Wolfgang und Allmendinger, Andrea
(2020):
Excipients for Room Temperature Stable Freeze-Dried Monoclonal Antibody Formulations.
In: Journal of Pharmaceutical Sciences, Bd. 109, Nr. 1: S. 807-817
Grapentin, Christoph; Müller, Claudia; Kishore, Ravuri S. K.; Adler, Michael; ElBialy, Inas; Friess, Wolfgang; Huwyler, Jörg und Khan, Tarik A.
(2020):
Protein-Polydimethylsiloxane Particles in Liquid Vial Monoclonal Antibody Formulations Containing Poloxamer 188.
In: Journal of Pharmaceutical Sciences, Bd. 109, Nr. 8: S. 2393-2404
Kulakova, Alina; Indrakumar, Sowmya; Sonderby, Pernille; Gentiluomo, Lorenzo; Streicher, Werner; Roessner, Dierk; Friess, Wolfgang; Peters, Guenther H. J. und Harris, Pernille
(2020):
Small angle X-ray scattering and molecular dynamic simulations provide molecular insight for stability of recombinant human transferrin.
In: Journal of Structural Biology-X, Bd. 4, 100017
Pohl, Christin; Zalar, Matja; El Bialy, Inas; Indrakumar, Sowmya; Peters, Gunther H. J.; Friess, Wolfgang; Golovanov, Alexander P.; Streicher, Werner W.; Noergaard, Allan und Harris, Pernille
(2020):
The Effect of Point Mutations on the Biophysical Properties of an Antimicrobial Peptide: Development of a Screening Protocol for Peptide Stability Screening.
In: Molecular Pharmaceutics, Bd. 17, Nr. 9: S. 3298-3313
Daller, Sarah; Friess, Wolfgang und Schroeder, Rudolf
(2020):
Energy Transfer in Vials Nested in a Rack System During Lyophilization.
In: Pharmaceutics, Bd. 12, Nr. 1, 61
Bluemel, Oliver; Buecheler, Jakob W.; Rodrigues, Miguel A.; Geraldes, Vitor; Hoelzl, Georg; Bechtold-Peters, Karoline und Friess, Wolfgang
(2020):
Cryoconcentration and 3D Temperature Profiles During Freezing of mAb Solutions in Large-Scale PET Bottles and a Novel Scale-Down Device.
In: Pharmaceutical Research, Bd. 37, Nr. 9, 179
Domnowski, Martin; Jaehrling, Jan und Friess, Wolfgang
(2020):
Assessment of Antibody Self-Interaction by Bio-Layer-Interferometry as a Tool for Early Stage Formulation Development.
In: Pharmaceutical Research, Bd. 37, Nr. 2, 29
Gentiluomo, Lorenzo; Svilenov, Hristo L.; Augustijn, Dillen; El Bialy, Inas; Greco, Maria Laura; Kulakova, Alina; Indrakumar, Sowmya; Mahapatra, Sujata; Morales, Marcello Martinez; Pohl, Christin; Roche, Aisling; Tosstorff, Andreas; Curtis, Robin; Derrick, Jeremy P.; Norgaard, Allan; Khan, Tarik A.; Peters, Gunther H. J.; Pluen, Alain; Rinnan, Asmund; Streicher, Werner W.; Walle, Christopher F. van der; Uddin, Shahid; Winter, Gerhard; Roessner, Dierk; Harris, Pernille und Friess, Wolfgang
(2020):
Advancing Therapeutic Protein Discovery and Development through Comprehensive Computational and Biophysical Characterization.
In: Molecular Pharmaceutics, Bd. 17, Nr. 2: S. 426-440
Gentiluomo, Lorenzo; Roessner, Dierk; Augustijn, Dillen; Svilenov, Hristo 
ORCID: https://orcid.org/0000-0001-5863-9569; Kulakova, Alina; Mahapatra, Sujata; Winter, Gerhard; Streicher, Werner; Rinnan, Asmund; Peters, Günther; Harris, Pernille und Friess, Wolfgang
(August 2019):
Application of interpretable artificial neural networks to early monoclonal antibodies development.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 141: S. 81-89
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ORCID: https://orcid.org/0000-0001-5863-9569; Kulakova, Alina; Mahapatra, Sujata; Winter, Gerhard; Streicher, Werner; Rinnan, Asmund; Peters, Günther; Harris, Pernille und Friess, Wolfgang
(August 2019):
Application of interpretable artificial neural networks to early monoclonal antibodies development.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 141: S. 81-89
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Horn, Jacqueline; Jena, Sampeeti; Aksan, Alptekin und Friess, Wolfgang
(2019):
Freeze/thaw of IGG solutions.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 134: S. 185-189
Yoneda, Saki; Niederleitner, Bertram; Wiggenhorn, Michael; Koga, Hiroki; Totoki, Shinichiro; Krayukhina, Elena; Friess, Wolfgang und Uchiyama, Susumu
(2019):
Quantitative Laser Diffraction for Quantification of Protein Aggregates: Comparison With Resonant Mass Measurement, Nanoparticle Tracking Analysis, Flow Imaging, and Light Obscuration.
In: Journal of Pharmaceutical Sciences, Bd. 108, Nr. 1: S. 755-762
Vollrath, Ilona; Friess, Wolfgang; Freitag, Angelika; Hawe, Andrea und Winter, Gerhard
(2019):
Comparison of ice fog methods and monitoring of controlled nucleation success after freeze-drying.
In: International Journal of Pharmaceutics, Bd. 558: S. 18-28
Duerr, Corinna und Friess, Wolfgang
(2019):
Antibody-drug conjugates- stability and formulation.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 139: S. 168-176
Higel, Fabian; Sandl, Theresa; Kao, Chi-Ya; Pechinger, Nicole; Soergel, Fritz; Friess, Wolfgang; Wolschin, Florian und Seidl, Andreas
(2019):
N-glycans of complex glycosylated biopharmaceuticals and their impact on protein clearance.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 139: S. 123-131
De Meyer, Laurens; Lammens, Joris; Vanbillemont, Brecht; Van Bockstal, Pieter Jan; Corver, Jos; Vervaet, Chris; Friess, Wolfgang und De Beer, Thomas
(2019):
Dual chamber cartridges in a continuous pharmaceutical freeze-drying concept: Determination of the optimal dynamic infrared heater temperature during primary drying.
In: International Journal of Pharmaceutics, Bd. 570, 118631
Haeuser, Christina; Goldbach, Pierre; Huwyler, Jörg; Friess, Wolfgang und Allmendinger, Andrea
(2019):
Be Aggressive! Amorphous Excipients Enabling Single-Step Freeze-Drying of Monoclonal Antibody Formulations.
In: Pharmaceutics, Bd. 11, Nr. 11, 616
Svilenov, Hristo ORCID: https://orcid.org/0000-0001-5863-9569; Gentiluomo, Lorenzo; Friess, Wolfgang; Roessner, Dierk und Winter, Gerhard
(Dezember 2018):
A New Approach to Study the Physical Stability of Monoclonal Antibody Formulations Dilution From a Denaturant.
In: Journal of Pharmaceutical Sciences, Bd. 107, Nr. 12: S. 3007-3013
[PDF, 1MB]
ORCID: https://orcid.org/0000-0001-5863-9569; Gentiluomo, Lorenzo; Friess, Wolfgang; Roessner, Dierk und Winter, Gerhard
(Dezember 2018):
A New Approach to Study the Physical Stability of Monoclonal Antibody Formulations Dilution From a Denaturant.
In: Journal of Pharmaceutical Sciences, Bd. 107, Nr. 12: S. 3007-3013
[PDF, 1MB]
Haeuser, Christina; Goldbach, Pierre; Huwyler, Jörg; Friess, Wolfgang und Allmendinger, Andrea
(2018):
Imaging Techniques to Characterize Cake Appearance of Freeze-Dried Products.
In: Journal of Pharmaceutical Sciences, Bd. 107, Nr. 11: S. 2810-2822
Horn, Jacqueline; Tolardo, Eleonora; Fissore, Davide und Friess, Wolfgang
(2018):
Crystallizing amino acids as bulking agents in freeze-drying.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 132: S. 70-82
Vollrath, Ilona; Friess, Wolfgang; Freitag, Angelika; Hawe, Andrea und Winter, Gerhard
(2018):
Does controlled nucleation impact the properties and stability of lyophilized monoclonal antibody formulations?
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 129: S. 134-144
Horn, Jacqueline; Schanda, Julia und Friess, Wolfgang
(2018):
Impact of fast and conservative freeze-drying on product quality of protein-mannitol-sucrose-glycerol lyophilizates.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 127: S. 342-354
Koepf, Ellen; Richert, Manuela; Braunschweig, Björn; Schröder, Rudolf; Brezesinski, Gerald und Friess, Wolfgang
(2018):
Impact of formulation pH on physicochemical protein characteristics at the liquid-air interface.
In: International Journal of Pharmaceutics, Bd. 541, Nr. 1-2: S. 234-245
Wang, Bifeng und Friess, Wolfgang
(2018):
Lipid-coated mannitol core microparticles for sustained release of protein.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 128: S. 91-97
Koepf, Ellen; Eisele, Simon; Schröder, Rudolf; Brezesinski, Gerald und Friess, Wolfgang
(2018):
Notorious but not understood: How liquid-air interfacial stress triggers protein aggregation.
In: International Journal of Pharmaceutics, Bd. 537, Nr. 1-2: S. 202-212
Koepf, Ellen; Schröder, Rudolf; Brezesinski, Gerald und Friess, Wolfgang
(2018):
The missing piece in the puzzle: Prediction of aggregation via the protein-protein interaction parameter A(2)*.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 128: S. 200-209
Yordanova, Yordanka; Vanderlinden, Willem; Stoll, Raphael; Rüdiger, Daniel; Tosstorff, Andreas; Zaremba, Wolfgang; Winter, Gerhard; Zahler, Stefan und Friess, Wolfgang
(2018):
Zn2+-triggered self-assembly of Gonadorelin [6-D-Phe] to produce nanostructures and fibrils.
In: Scientific Reports, Bd. 8, 11280
[PDF, 3MB]
Horn, Jacqueline und Friess, Wolfgang
(2018):
Detection of Collapse and Crystallization of Saccharide, Protein, and Mannitol Formulations by Optical Fibers in Lyophilization.
In: Frontiers in Chemistry, Bd. 6, 4
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Saller, Verena; Hediger, Constanze; Matilainen, Julia; Grauschopf, Ulla; Bechtold-Peters, Karoline; Mahler, Hanns-Christian und Friess, Wolfgang
(2018):
Influence of particle shedding from silicone tubing on antibody stability.
In: Journal of Pharmacy and Pharmacology, Bd. 70, Nr. 5: S. 675-685
Korpus, Christoph und Friess, Wolfgang
(2017):
Evaluation of Different Holder Devices for Freeze-Drying in Dual-Chamber Cartridges With a Focus on Energy Transfer.
In: Journal of Pharmaceutical Sciences, Bd. 106, Nr. 4: S. 1092-1101
Martos, Ariadna; Koch, Wendelin; Jiskoot, Wim; Wuchner, Klaus; Winter, Gerhard; Friess, Wolfgang und Hawe, Andrea
(2017):
Trends on Analytical Characterization of Polysorbates and Their Degradation Products in Biopharmaceutical Formulations.
In: Journal of Pharmaceutical Sciences, Bd. 106, Nr. 7: S. 1722-1735
Wang, Bifeng und Friess, Wolfgang
(2017):
Spray drying of silica microparticles for sustained release application with a new sol-gel precursor.
In: International Journal of Pharmaceutics, Bd. 532, Nr. 1: S. 281-288
Köpf, Ellen; Schröder, Rudolf; Brezesinski, Gerald und Friess, Wolfgang
(2017):
The film tells the story: Physical-chemical characteristics of IgG at the liquid-air interface.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 119: S. 396-407
Korpus, Christoph und Friess, Wolfgang
(2017):
Lyophilization Cycle Design for Dual Chamber Cartridges and a Method for Online Process Control: The "DCC LyoMate" Procedure.
In: Journal of Pharmaceutical Sciences, Bd. 106, Nr. 8: S. 2077-2087
Vollrath, Ilona; Pauli, Victoria; Friess, Wolfgang; Freitag, Angelika; Hawe, Andrea und Winter, Gerhard
(2017):
Evaluation of Heat Flux Measurement as a New Process Analytical Technology Monitoring Tool in Freeze Drying.
In: Journal of Pharmaceutical Sciences, Bd. 106, Nr. 5: S. 1249-1257
Saller, Verena; Matilainen, Julia; Rothkopf, Christian; Serafin, Daniel; Bechtold-Peters, Karoline; Mahler, Hanns-Christian und Friess, Wolfgang
(2017):
Preservative loss from silicone tubing during filling processes.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 112: S. 109-118
Jena, Sampreeti; Horn, Jacqueline; Suryanarayanan, Raj; Friess, Wolfgang und Aksan, Alptekin
(2017):
Effects of Excipient Interactions on the State of the Freeze-Concentrate and Protein Stability.
In: Pharmaceutical Research, Bd. 34, Nr. 2: S. 462-478
Strüver, Kay; Friess, Wolfgang und Hedtrich, Sarah
(2017):
Development of a Perfusion Platform for Dynamic Cultivation of in vitro Skin Models.
In: Skin Pharmacology and Physiology, Bd. 30, Nr. 4: S. 180-189
Funke, Stefanie; Matilainen, Julia; Nalenz, Heiko; Bechtold-Peters, Karoline; Mahler, Hanns-Christian und Friess, Wolfgang
(2016):
Silicone Migration From Baked-on Silicone Layers. Particle Characterization in Placebo and Protein Solutions.
In: Journal of Pharmaceutical Sciences, Bd. 105, Nr. 12: S. 3520-3531
Funke, Stefanie; Matilainen, Julia; Nalenz, Heiko; Bechtold-Peters, Karoline; Mahler, Hanns-Christian; Vetter, Florian; Müller, Christoph; Bracher, Franz und Friess, Wolfgang
(2016):
Optimization of the bake-on siliconization of cartridges. Part II: Investigations into burn-in time and temperature.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 105: S. 209-222
Funke, Stefanie; Matilainen, Julia; Nalenz, Heiko; Bechtold-Peters, Karoline; Mahler, Hanns-Christian und Friess, Wolfgang
(2016):
Optimization of the bake-on siliconization of cartridges. Part I: Optimization of the spray-on parameters.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 104: S. 200-215
Higel, Fabian; Seidl, Andreas; Sörgel, Fritz und Friess, Wolfgang
(2016):
N-glycosylation heterogeneity and the influence on structure, function and pharmacokinetics of monoclonal antibodies and Fc fusion proteins.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 100: S. 94-100
Korpus, Christoph; Pikal, Michael und Friess, Wolfgang
(2016):
Heat Transfer Analysis of an Optimized, Flexible Holder System for Freeze-Drying in Dual Chamber Cartridges Using Different State-of-the-Art PAT Tools.
In: Journal of Pharmaceutical Sciences, Bd. 105, Nr. 11: S. 3304-3313
Heckmann, S.M.; Hujoel, P.; Habiger, S.; Friess, Wolfgang; Wichmann, M.; Heckmann, J.G. und Hummel, T.
(2005):
Zinc Gluconate in the Treatment of Dysgeusia—a Randomized Clinical Trial.
In: Journal of Dental Research, Bd. 84, Nr. 1: S. 35-38
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