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Anzahl der Publikationen: 134

Zeitschriftenartikel

Reich, Marvin ORCID logoORCID: https://orcid.org/0000-0002-4567-0994; Simon, Matthew J. ORCID logoORCID: https://orcid.org/0000-0002-0065-6486; Polke, Beate; Paris, Iñaki ORCID logoORCID: https://orcid.org/0000-0002-3887-0277; Werner, Georg ORCID logoORCID: https://orcid.org/0000-0001-5328-3049; Schrader, Christian; Spieth, Lena; Davis, Sonnet S. ORCID logoORCID: https://orcid.org/0000-0001-7189-1427; Robinson, Sophie ORCID logoORCID: https://orcid.org/0000-0003-1261-1370; de Melo, Gabrielly Lunkes ORCID logoORCID: https://orcid.org/0009-0002-1342-3080; Schlaphoff, Lennart ORCID logoORCID: https://orcid.org/0000-0001-8043-4025; Buschmann, Katrin; Berghoff, Stefan ORCID logoORCID: https://orcid.org/0000-0002-3794-7295; Logan, Todd ORCID logoORCID: https://orcid.org/0000-0003-2081-782X; Nuscher, Brigitte ORCID logoORCID: https://orcid.org/0009-0000-4661-0742; de Weerd, Lis ORCID logoORCID: https://orcid.org/0000-0002-3641-1851; Edbauer, Dieter ORCID logoORCID: https://orcid.org/0000-0002-7186-4653; Simons, Mikael ORCID logoORCID: https://orcid.org/0000-0001-5329-192X; Suh, Jung H. ORCID logoORCID: https://orcid.org/0000-0001-8119-326X; Sandmann, Thomas ORCID logoORCID: https://orcid.org/0000-0002-6601-8890; Kariolis, Mihalis S. ORCID logoORCID: https://orcid.org/0000-0003-2067-4013; DeVos, Sarah L. ORCID logoORCID: https://orcid.org/0000-0003-0921-1763; Lewcock, Joseph W. ORCID logoORCID: https://orcid.org/0000-0003-3012-7881; Paquet, Dominik ORCID logoORCID: https://orcid.org/0000-0003-2065-1639; Capell, Anja ORCID logoORCID: https://orcid.org/0000-0003-3118-911X; Di Paolo, Gilbert ORCID logoORCID: https://orcid.org/0000-0003-1032-1265 und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2024): Peripheral expression of brain-penetrant progranulin rescues pathologies in mouse models of frontotemporal lobar degeneration. In: Science Translational Medicine, Bd. 16, Nr. 750

Ramalingam, Nagendran; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 und Dettmer, Ulf ORCID logoORCID: https://orcid.org/0000-0001-6676-0107 (2024): Physiological roles of α-synuclein serine-129 phosphorylation – not an oxymoron. In: Trends in Neurosciences, Bd. 47, Nr. 7: S. 480-490

Hu, Yiying; Hruscha, Alexander; Pan, Chenchen; Schifferer, Martina; Schmidt, Michael K.; Nuscher, Brigitte ORCID logoORCID: https://orcid.org/0009-0000-4661-0742; Giera, Martin; Kostidis, Sarantos; Burhan, Özge; Bebber, Frauke van; Edbauer, Dieter ORCID logoORCID: https://orcid.org/0000-0002-7186-4653; Arzberger, Thomas; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 und Schmid, Bettina ORCID logoORCID: https://orcid.org/0000-0001-8043-7269 (2024): Mis-localization of endogenous TDP-43 leads to ALS-like early-stage metabolic dysfunction and progressive motor deficits. In: Molecular Neurodegeneration, Bd. 19, 50 [PDF, 6MB]

Piollet, Marie ORCID logoORCID: https://orcid.org/0000-0002-2025-6594; Porsch, Florentina ORCID logoORCID: https://orcid.org/0000-0002-2633-6632; Rizzo, Giuseppe; Kapser, Frederieke; Schulz, Dirk J. J.; Kiss, Máté G.; Schlepckow, Kai; Morenas-Rodriguez, Estrella; Sen, Mustafa Orkun; Gropper, Julius; Bandi, Sourish Reddy; Schäfer, Sarah; Krammer, Tobias ORCID logoORCID: https://orcid.org/0000-0002-7638-9476; Leipold, Alexander M.; Hoke, Matthias; Ozsvár-Kozma, Mária; Beneš, Hannah; Schillinger, Martin; Minar, Erich; Roesch, Melanie; Göderle, Laura ORCID logoORCID: https://orcid.org/0000-0003-1037-3137; Hladik, Anastasiya; Knapp, Sylvia ORCID logoORCID: https://orcid.org/0000-0001-9016-5244; Colonna, Marco ORCID logoORCID: https://orcid.org/0000-0001-5222-4987; Martini, Rudolf; Saliba, Antoine-Emmanuel ORCID logoORCID: https://orcid.org/0000-0001-8539-2784; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Zernecke, Alma ORCID logoORCID: https://orcid.org/0000-0001-8551-4729; Binder, Christoph J. ORCID logoORCID: https://orcid.org/0000-0001-8313-7050 und Cochain, Clément ORCID logoORCID: https://orcid.org/0000-0002-0340-1745 (2024): TREM2 protects from atherosclerosis by limiting necrotic core formation. In: Nature Cardiovascular Research, Bd. 3, Nr. 3: S. 269-282 [PDF, 11MB]

Zatcepin, Artem ORCID logoORCID: https://orcid.org/0000-0002-0224-088X; Gnörich, Johannes ORCID logoORCID: https://orcid.org/0000-0003-1554-7765; Rauchmann, Boris-Stephan ORCID logoORCID: https://orcid.org/0000-0003-4547-6240; Bartos, Laura M.; Wagner, Stephan; Franzmeier, Nicolai ORCID logoORCID: https://orcid.org/0000-0001-9736-2283; Malpetti, Maura ORCID logoORCID: https://orcid.org/0000-0001-8923-9656; Xiang, Xianyuan; Shi, Yuan; Parhizkar, Samira; Grosch, Maximilian; Wind-Mark, Karin; Kunte, Sebastian T.; Beyer, Leonie; Meyer, Carolin; Brösamle, Desirée; Wendeln, Ann-Christin; Osei-Sarpong, Collins; Heindl, Steffanie; Liesz, Arthur ORCID logoORCID: https://orcid.org/0000-0002-9069-2594; Stoecklein, Sophia; Biechele, Gloria; Finze, Anika; Eckenweber, Florian; Lindner, Simon ORCID logoORCID: https://orcid.org/0009-0007-4379-4436; Rominger, Axel ORCID logoORCID: https://orcid.org/0000-0002-1954-736X; Bartenstein, Peter ORCID logoORCID: https://orcid.org/0009-0005-0734-4994; Willem, Michael; Tahirovic, Sabina ORCID logoORCID: https://orcid.org/0000-0003-4403-9559; Herms, Jochen; Buerger, Katharina; Simons, Mikael ORCID logoORCID: https://orcid.org/0000-0001-5329-192X; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Rupprecht, Rainer ORCID logoORCID: https://orcid.org/0000-0003-2939-9062; Riemenschneider, Markus J.; Albert, Nathalie L. ORCID logoORCID: https://orcid.org/0000-0003-0953-7624; Beyer, Marc; Neher, Jonas J.; Paeger, Lars; Levin, Johannes ORCID logoORCID: https://orcid.org/0000-0001-5092-4306; Höglinger, Günter U. ORCID logoORCID: https://orcid.org/0000-0001-7587-6187; Perneczky, Robert ORCID logoORCID: https://orcid.org/0000-0003-1981-7435; Ziegler, Sibylle I. ORCID logoORCID: https://orcid.org/0000-0002-5321-4817 und Brendel, Matthias ORCID logoORCID: https://orcid.org/0000-0002-9247-2843 (2024): Regional desynchronization of microglial activity is associated with cognitive decline in Alzheimer’s disease. In: Molecular Neurodegeneration, Bd. 19, 64 [PDF, 6MB]

Katzdobler, Sabrina ORCID logoORCID: https://orcid.org/0000-0002-3512-5984; Nübling, Georg; Klietz, Martin; Fietzek, Urban M.; Palleis, Carla ORCID logoORCID: https://orcid.org/0000-0002-4331-8145; Bernhardt, Alexander M. ORCID logoORCID: https://orcid.org/0000-0002-2572-5062; Wegner, Florian ORCID logoORCID: https://orcid.org/0000-0002-9931-2666; Huber, Meret; Rogozinski, Sophia; Schneider, Luisa-Sophie; Spruth, Eike Jakob; Beyle, Aline; Vogt, Ina R.; Brandt, Moritz; Hansen, Niels; Glanz, Wenzel ORCID logoORCID: https://orcid.org/0000-0002-5865-4176; Brockmann, Kathrin ORCID logoORCID: https://orcid.org/0000-0002-7515-8596; Spottke, Annika; Hoffmann, Daniel C.; Peters, Oliver; Priller, Josef ORCID logoORCID: https://orcid.org/0000-0001-7596-0979; Wiltfang, Jens ORCID logoORCID: https://orcid.org/0000-0003-1492-5330; Düzel, Emrah ORCID logoORCID: https://orcid.org/0000-0002-0139-5388; Schneider, Anja ORCID logoORCID: https://orcid.org/0000-0001-9540-8700; Falkenburger, Björn; Klockgether, Thomas ORCID logoORCID: https://orcid.org/0000-0001-6174-5442; Gasser, Thomas ORCID logoORCID: https://orcid.org/0000-0002-1069-1146; Nuscher, Brigitte ORCID logoORCID: https://orcid.org/0009-0000-4661-0742; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Höglinger, Günter ORCID logoORCID: https://orcid.org/0000-0001-7587-6187 und Levin, Johannes ORCID logoORCID: https://orcid.org/0000-0001-5092-4306 (2024): GFAP and NfL as fluid biomarkers for clinical disease severity and disease progression in multiple system atrophy (MSA). In: Journal of Neurology, Bd. 271: S. 6991-6999 [PDF, 1MB]

Palleis, Carla; Franzmeier, Nicolai; Weidinger, Endy; Bernhardt, Alexander M.; Katzdobler, Sabrina; Wall, Stephan; Ferschmann, Christian; Harris, Stefanie; Schmitt, Julia; Schuster, Sebastian; Gnoerich, Johannes; Finze, Anika; Biechele, Gloria; Lindner, Simon; Albert, Nathalie L.; Bartenstein, Peter; Sabri, Osama; Barthel, Henryk; Rupprecht, Rainer; Nuscher, Brigitte; Stephens, Andrew W.; Rauchmann, Boris-Stephan; Perneczky, Robert; Haass, Christian; Brendel, Matthias; Levin, Johannes und Hoeglinger, Guenter U. (2024): Association of Neurofilament Light Chain, [18F]PI-2620 Tau-PET, TSPO-PET, and Clinical Progression in Patients With β-Amyloid-Negative CBS. In: Neurology, Bd. 102, Nr. 1, e207901 [PDF, 2MB]

Yu, Chen; Lad, Eleonora M.; Mathew, Rose; Shiraki, Nobuhiko; Littleton, Sejiro; Chen, Yun; Hou, Jinchao; Schlepckow, Kai; Degan, Simone; Chew, Lindsey; Amason, Joshua; Kalnitsky, Joan; Bowes Rickman, Catherine; Proia, Alan D.; Colonna, Marco; Haass, Christian und Saban, Daniel R. (2024): Microglia at sites of atrophy restrict the progression of retinal degeneration via galectin-3 and Trem2. In: Journal of Experimental Medicine, Bd. 221, Nr. 3, e20231011

Todorov-Voelgyi, Katalin; Gonzalez-Gallego, Judit; Mueller, Stephan A.; Beaufort, Nathalie; Malik, Rainer; Schifferer, Martina; Todorov, Mihail Ivilinov; Crusius, Dennis; Robinson, Sophie; Schmidt, Andree; Koerbelin, Jakob; Bareyre, Florence; Ertuerk, Ali; Haass, Christian; Simons, Mikael; Paquet, Dominik; Lichtenthaler, Stefan F. und Dichgans, Martin ORCID logoORCID: https://orcid.org/0000-0002-0654-387X (2024): Proteomics of mouse brain endothelium uncovers dysregulation of vesicular transport pathways during aging. In: Nature Aging, Bd. 4, Nr. 4 [PDF, 170MB]

Finze, Anika; Biechele, Gloria; Rauchmann, Boris-Stephan; Franzmeier, Nicolai ORCID logoORCID: https://orcid.org/0000-0001-9736-2283; Palleis, Carla; Katzdobler, Sabrina; Weidinger, Endy; Guersel, Selim ORCID logoORCID: https://orcid.org/0000-0001-6714-5827; Schuster, Sebastian; Harris, Stefanie; Schmitt, Julia; Beyer, Leonie; Gnörich, Johannes; Lindner, Simon; Albert, Nathalie L. ORCID logoORCID: https://orcid.org/0000-0003-0953-7624; Wetzel, Christian H. ORCID logoORCID: https://orcid.org/0000-0002-5762-0003; Rupprecht, Rainer ORCID logoORCID: https://orcid.org/0000-0003-2939-9062; Rominger, Axel ORCID logoORCID: https://orcid.org/0000-0002-1954-736X; Danek, Adrian ORCID logoORCID: https://orcid.org/0000-0001-8857-5383; Burow, Lena; Kurz, Carolin; Tato, Maia; Utecht, Julia; Papazov, Boris; Zaganjori, Mirlind; Trappmann, Lena-Katharina; Goldhardt, Oliver; Grimmer, Timo; Haeckert, Jan; Janowitz, Daniel; Buerger, Katharina; Keeser, Daniel ORCID logoORCID: https://orcid.org/0000-0002-0244-1024; Stoecklein, Sophia; Dietrich, Olaf ORCID logoORCID: https://orcid.org/0000-0001-6182-5039; Morenas-Rodriguez, Estrella; Barthel, Henryk; Sabri, Osama ORCID logoORCID: https://orcid.org/0000-0002-6425-3504; Bartenstein, Peter; Simons, Mikael; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Höglinger, Günter U. ORCID logoORCID: https://orcid.org/0000-0001-7587-6187; Levin, Johannes; Perneczky, Robert ORCID logoORCID: https://orcid.org/0000-0003-1981-7435 und Brendel, Matthias ORCID logoORCID: https://orcid.org/0000-0002-9247-2843 (2023): Individual regional associations between Aβ-, tau- and neurodegeneration (ATN) with microglial activation in patients with primary and secondary tauopathies. In: Molecular Psychiatry, Bd. 28, Nr. 10: S. 4438-4450 [PDF, 4MB]

Biel, Davina ORCID logoORCID: https://orcid.org/0000-0002-2597-1992; Suárez‐Calvet, Marc ORCID logoORCID: https://orcid.org/0000-0002-2993-569X; Hager, Paul; Rubinski, Anna; Dewenter, Anna; Steward, Anna; Roemer, Sebastian; Ewers, Michael; Haass, Christian; Brendel, Matthias ORCID logoORCID: https://orcid.org/0000-0002-9247-2843 und Franzmeier, Nicolai ORCID logoORCID: https://orcid.org/0000-0001-9736-2283 (2023): sTREM2 is associated with amyloid‐related p‐tau increases and glucose hypermetabolism in Alzheimer's disease. In: EMBO Molecular Medicine, Bd. 15, Nr. 2 [PDF, 1MB]

Kolabas, Zeynep Ilgin; Kuemmerle, Louis B.; Perneczky, Robert; Förstera, Benjamin; Ulukaya, Selin; Ali, Mayar; Kapoor, Saketh; Bartos, Laura M.; Büttner, Maren; Caliskan, Ozum Sehnaz; Rong, Zhouyi; Mai, Hongcheng; Höher, Luciano; Jeridi, Denise; Molbay, Muge; Khalin, Igor; Deligiannis, Ioannis K.; Negwer, Moritz; Roberts, Kenny; Simats, Alba; Carofiglio, Olga; Todorov, Mihail I.; Horvath, Izabela; Ozturk, Furkan; Hummel, Selina; Biechele, Gloria; Zatcepin, Artem; Unterrainer, Marcus; Gnörich, Johannes; Roodselaar, Jay; Shrouder, Joshua; Khosravani, Pardis; Tast, Benjamin; Richter, Lisa; Díaz-Marugán, Laura; Kaltenecker, Doris; Lux, Laurin; Chen, Ying; Zhao, Shan; Rauchmann, Boris-Stephan; Sterr, Michael; Kunze, Ines; Stanic, Karen; Kan, Vanessa W.Y.; Besson-Girard, Simon; Katzdobler, Sabrina; Palleis, Carla; Schädler, Julia; Paetzold, Johannes C.; Liebscher, Sabine; Hauser, Anja E.; Gokce, Ozgun; Lickert, Heiko; Steinke, Hanno; Benakis, Corinne; Braun, Christian; Martinez-Jimenez, Celia P.; Buerger, Katharina; Albert, Nathalie L.; Höglinger, Günter; Levin, Johannes; Haass, Christian; Kopczak, Anna; Dichgans, Martin ORCID logoORCID: https://orcid.org/0000-0002-0654-387X; Havla, Joachim ORCID logoORCID: https://orcid.org/0000-0002-4386-1340; Kümpfel, Tania; Kerschensteiner, Martin; Schifferer, Martina; Simons, Mikael; Liesz, Arthur ORCID logoORCID: https://orcid.org/0000-0002-9069-2594; Krahmer, Natalie; Bayraktar, Omer A.; Franzmeier, Nicolai ORCID logoORCID: https://orcid.org/0000-0001-9736-2283; Plesnila, Nikolaus; Erener, Suheda; Puelles, Victor G.; Delbridge, Claire; Bhatia, Harsharan Singh; Hellal, Farida; Elsner, Markus; Bechmann, Ingo; Ondruschka, Benjamin; Brendel, Matthias; Theis, Fabian J. und Erturk, Ali (2023): Distinct molecular profiles of skull bone marrow in health and neurological disorders. In: Cell, Bd. 186, Nr. 17, 3706-3725.e29 [PDF, 19MB]

Hipke, Katrin; Pitter, Bettina; Hruscha, Alexander; van Bebber, Frauke; Modic, Miha; Bansal, Vikas; Lewandowski, Sebastian A.; Orozco, Denise; Edbauer, Dieter; Bonn, Stefan; Haass, Christian; Pohl, Ulrich; Montanez, Eloi und Schmid, Bettina (2023): Loss of TDP-43 causes ectopic endothelial sprouting and migration defects through increased fibronectin, vcam 1 and integrin α4/β1. In: Frontiers in Cell and Developmental Biology, Bd. 11, 1169962 [PDF, 3MB]

Biel, Davina; Suarez-Calvet, Marc; Hager, Paul; Rubinski, Anna; Dewenter, Anna; Steward, Anna; Roemer, Sebastian; Ewers, Michael; Haass, Christian; Brendel, Matthias und Franzmeier, Nicolai (2023): sTREM2 is associated with amyloid-related p-tau increases and glucose hypermetabolism in Alzheimer's disease. In: EMBO Molecular Medicine, Bd. 15, Nr. 2 [PDF, 1MB]

Pesaemaa, Ida; Mueller, Stephan A.; Robinson, Sophie; Darcher, Alana; Paquet, Dominik; Zetterberg, Henrik; Lichtenthaler, Stefan F. und Haass, Christian (2023): A microglial activity state biomarker panel differentiates FTD-granulin and Alzheimer's disease patients from controls. In: Molecular Neurodegeneration, Bd. 18, Nr. 1, 70 [PDF, 5MB]

Gnoerich, Johannes; Reifschneider, Anika; Wind, Karin; Zatcepin, Artem; Kunte, Sebastian T.; Beumers, Philipp; Bartos, Laura M.; Wiedemann, Thomas; Grosch, Maximilian; Xiang, Xianyuan; Fard, Maryam K.; Ruch, Francois; Werner, Georg; Koehler, Mara; Slemann, Luna; Hummel, Selina; Briel, Nils; Blume, Tanja; Shi, Yuan; Biechele, Gloria; Beyer, Leonie; Eckenweber, Florian; Scheifele, Maximilian; Bartenstein, Peter; Albert, Nathalie L.; Herms, Jochen; Tahirovic, Sabina; Haass, Christian; Capell, Anja; Ziegler, Sibylle und Brendel, Matthias (2023): Depletion and activation of microglia impact metabolic connectivity of the mouse brain. In: Journal of Neuroinflammation, Bd. 20, Nr. 1, 47 [PDF, 9MB]

van Lengerich, Bettina; Zhan, Lihong; Xia, Dan; Chan, Darren; Joy, David; Park, Joshua I.; Tatarakis, David; Calvert, Meredith; Hummel, Selina; Lianoglou, Steve; Pizzo, Michelle E.; Prorok, Rachel; Thomsen, Elliot; Bartos, Laura M.; Beumers, Philipp; Capell, Anja; Davis, Sonnet S.; de Weerd, Lis; Dugas, Jason C.; Duque, Joseph; Earr, Timothy; Gadkar, Kapil; Giese, Tina; Gill, Audrey; Gnoerich, Johannes; Ha, Connie; Kannuswamy, Malavika; Kim, Do Jin; Kunte, Sebastian T.; Kunze, Lea H.; Lac, Diana; Lechtenberg, Kendra; Leung, Amy Wing-Sze; Liang, Chun-Chi; Lopez, Isabel; McQuade, Paul; Modi, Anuja; Torres, Vanessa O.; Nguyen, Hoang N.; Pesaemaa, Ida; Propson, Nicholas; Reich, Marvin; Robles-Colmenares, Yaneth; Schlepckow, Kai; Slemann, Luna; Solanoy, Hilda; Suh, Jung H.; Thorne, Robert G.; Vieira, Chandler; Wind-Mark, Karin; Xiong, Ken; Zuchero, Y. Joy Yu; Diaz, Dolo; Dennis, Mark S.; Huang, Fen; Scearce-Levie, Kimberly; Watts, Ryan J.; Haass, Christian; Lewcock, Joseph W.; Di Paolo, Gilbert; Brendel, Matthias; Sanchez, Pascal E. und Monroe, Kathryn M. (2023): A TREM2-activating antibody with a blood-brain barrier transport vehicle enhances microglial metabolism in Alzheimer's disease models. In: Nature Neuroscience, Bd. 26, Nr. 3: 416-+ [PDF, 13MB]

Johnson, Erik C. B.; Bian, Shijia; Haque, Rafi U.; Carter, E. Kathleen; Watson, Caroline M.; Gordon, Brian A.; Ping, Lingyan; Duong, Duc M.; Epstein, Michael P.; McDade, Eric; Barthelemy, Nicolas R.; Karch, Celeste M.; Xiong, Chengjie; Cruchaga, Carlos; Perrin, Richard J.; Wingo, Aliza P.; Wingo, Thomas S.; Chhatwal, Jasmeer P.; Day, Gregory S.; Noble, James M.; Berman, Sarah B.; Martins, Ralph; Graff-Radford, Neill R.; Schofield, Peter R.; Ikeuchi, Takeshi; Mori, Hiroshi; Levin, Johannes; Farlow, Martin; Lah, James J.; Haass, Christian; Jucker, Mathias; Morris, John C.; Benzinger, Tammie L. S.; Roberts, Blaine R.; Bateman, Randall J.; Fagan, Anne M.; Seyfried, Nicholas T. und Levey, Allan (2023): Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease. In: Nature Medicine, Bd. 29, Nr. 8: 1979-+ [PDF, 7MB]

Depp, Constanze; Sun, Ting; Sasmita, Andrew Octavian; Spieth, Lena; Berghoff, Stefan A.; Nazarenko, Taisiia; Overhoff, Katharina; Steixner-Kumar, Agnes A.; Subramanian, Swati; Arinrad, Sahab; Ruhwedel, Torben; Moebius, Wiebke; Goebbels, Sandra; Saher, Gesine; Werner, Hauke B.; Damkou, Alkmini; Zampar, Silvia; Wirths, Oliver; Thalmann, Maik; Simons, Mikael; Saito, Takashi; Saido, Takaomi; Krueger-Burg, Dilja; Kawaguchi, Riki; Willem, Michael; Haass, Christian; Geschwind, Daniel; Ehrenreich, Hannelore; Stassart, Ruth und Nave, Klaus-Armin (2023): Myelin dysfunction drives amyloid-β deposition in models of Alzheimer's disease. In: Nature, Bd. 618, Nr. 7964: S. 349-357 [PDF, 20MB]

Finze, Anika; Biechele, Gloria; Rauchmann, Boris-Stephan; Franzmeier, Nicolai; Palleis, Carla; Katzdobler, Sabrina; Weidinger, Endy; Guersel, Selim; Schuster, Sebastian; Harris, Stefanie; Schmitt, Julia; Beyer, Leonie; Gnoerich, Johannes; Lindner, Simon; Albert, Nathalie L.; Wetzel, Christian H.; Rupprecht, Rainer; Rominger, Axel; Danek, Adrian; Burow, Lena; Kurz, Carolin; Tato, Maia; Utecht, Julia; Papazov, Boris; Zaganjori, Mirlind; Trappmann, Lena-Katharina; Goldhardt, Oliver; Grimmer, Timo; Haeckert, Jan; Janowitz, Daniel; Buerger, Katharina; Keeser, Daniel; Stoecklein, Sophia; Dietrich, Olaf; Morenas-Rodriguez, Estrella; Barthel, Henryk; Sabri, Osama; Bartenstein, Peter; Simons, Mikael; Haass, Christian; Hoeglinger, Gunter U.; Levin, Johannes; Perneczky, Robert und Brendel, Matthias (2023): Individual regional associations between Aβ-, tau- and neurodegeneration (ATN) with microglial activation in patients with primary and secondary tauopathies. In: Molecular Psychiatry, Bd. 28, Nr. 10: S. 4438-4450 [PDF, 4MB]

Kloske, Courtney M.; Barnum, Christopher J.; Batista, Andre F.; Bradshaw, Elizabeth M.; Brickman, Adam M.; Bu, Guojun; Dennison, Jessica; Gearon, Mary D.; Goate, Alison M.; Haass, Christian; Heneka, Michael T.; Hu, William T.; Huggins, Lenique K. L.; Jones, Nahdia S.; Koldamova, Radosveta; Lemere, Cynthia A.; Liddelow, Shane A.; Marcora, Edoardo; Marsh, Samuel E.; Nielsen, Henrietta M.; Petersen, Kellen K.; Petersen, Melissa; Pina-Escudero, Stefanie D.; Qiu, Wei Qiao; Quiroz, Yakeel T.; Reiman, Eric; Sexton, Claire; Tansey, Malu Gamez; Julia, T. C. W.; Teunissen, Charlotte E.; Tijms, Betty M.; van der Kant, Rik; Wallings, Rebecca; Weninger, Stacie C.; Wharton, Whitney; Wilcock, Donna M.; Wishard, Tyler James; Worley, Susan L.; Zetterberg, Henrik und Carrillo, Maria C. (2023): APOE and immunity: Research highlights. In: Alzheimers & Dementia [PDF, 430kB]

Schlepckow, Kai; Morenas-Rodríguez, Estrella; Hong, Soyon und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2023): Stimulation of TREM2 with agonistic antibodies—an emerging therapeutic option for Alzheimer's disease. In: Lancet Neurology, Bd. 22, Nr. 11: S. 1048-1060

Ali, Muhammad M.; Sung, Yun Ju; Wang, Fengxian; Fernandez, Maria; Morris, John M.; Fagan, Anne; Blennow, Kaj; Zetterberg, Henrik; Heslegrave, Amanda; Johansson, Per; Svensson, Johan; Nellgard, Bengt; Lleo, Alberto; Alcolea, Daniel; Clarimon, Jordi; Rami, Lorena; Molinuevo, Jose Luis; Suarez-Calvet, Marc; Morenas-Rodriguez, Estrella R.; Kleinberger, Gernot J.; Haass, Christian; Ewers, Michael; Levin, Johannes; Farlow, Martin; Perrin, Richard und Cruchaga, Carlos (2022): Leveraging large multi-center cohorts of Alzheimer disease endophenotypes to understand the role of Klotho heterozygosity on disease risk.
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Eninger, Timo; Mueller, Stephan A.; Bacioglu, Mehtap; Schweighauser, Manuel; Lambert, Marius; Maia, Luis F.; Neher, Jonas J.; Hornfeck, Sarah M.; Obermueller, Ulrike; Kleinberger, Gernot; Haass, Christian; Kahle, Philipp J.; Staufenbiel, Matthias; Ping, Lingyan; Duong, Duc M.; Levey, Allan I.; Seyfried, Nicholas T.; Lichtenthaler, Stefan F.; Jucker, Mathias und Kaeser, Stephan A. (2022): Signatures of glial activity can be detected in the CSF proteome. In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 119, Nr. 24, e2119804119 [PDF, 2MB]

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Zhou, Qihui; Mareljic, Nikola; Michaelsen, Meike; Parhizkar, Samira; Heindl, Steffanie; Nuscher, Brigitte; Farny, Daniel; Czuppa, Mareike; Schludi, Carina; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Feederle, Regina; Roth, Stefan; Haass, Christian; Arzberger, Thomas; Liesz, Arthur und Edbauer, Dieter (2019): Active poly-GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model. In: EMBO Molecular Medicine, e10919 [PDF, 969kB]

Nihei, Yoshihiro; Mori, Kohji; Werner, Georg; Arzberger, Thomas; Zhou, Qihui; Khosravi, Barham; Japtok, Julia; Hermann, Andreas; Sommacal, Andreas; Weber, Markus; Kamp, Frits; Nuscher, Brigitte; Edbauer, Dieter und Haass, Christian (2019): Poly-glycine-alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3. In: Acta Neuropathologica, Bd. 139, Nr. 1: S. 99-118 [PDF, 3MB]

Haass, Christian und Levin, Johannes (2019): Hat die Alzheimer-Forschung versagt? Das Scheitern amyloidbasierter klinischer Studien. In: Nervenarzt, Bd. 90, Nr. 9: S. 884-890 [PDF, 333kB]

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Deming, Yuetiva; Filipello, Fabia; Cignarella, Francesca; Cantoni, Claudia; Hsu, Simon; Mikesell, Robert; Li, Zeran; Del-Aguila, Jörge L.; Dube, Umber; Farias, Fabiana Geraldo; Bradley, Joseph; Budde, John; Ibanez, Laura; Fernandez, Maria Victoria; Blennow, Kaj; Zetterberg, Henrik; Heslegrave, Amanda; Johansson, Per M.; Svensson, Johan; Nellgard, Bengt; Lleo, Alberto; Alcolea, Daniel; Clarimon, Jordi; Rami, Lorena; Molinuevo, Jose Luis; Suarez-Calvet, Marc; Morenas-Rodriguez, Estrella; Kleinberger, Gernot; Ewers, Michael; Harari, Oscar; Haass, Christian; Brett, Thomas J.; Benitez, Bruno A.; Karch, Celeste M.; Piccio, Laura und Cruchaga, Carlos (2019): The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk. In: Science Translational Medicine, Bd. 11, Nr. 505, eaau2291 [PDF, 1MB]

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Parhizkar, Samira; Arzberger, Thomas; Brendel, Matthias; Kleinberger, Gernot; Deussing, Maximilian; Focke, Carola; Nuscher, Brigitte; Xiong, Monica; Ghasemigharagoz, Alireza; Katzmarski, Natalie; Krasemann, Susanne; Lichtenthaler, Stefan F.; Müller, Stephan A.; Colombo, Alessio; Monasor, Laura Sebastian; Tahirovic, Sabina; Herms, Jochen; Willem, Michael; Pettkus, Nadine; Butovsky, Oleg; Bartenstein, Peter; Edbauer, Dieter; Rominger, Axel; Ertuerk, Ali; Grathwohl, Stefan A.; Neher, Jonas J.; Holtzman, David M.; Meyer-Luehmann, Melanie und Haass, Christian (2019): Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE. In: Nature Neuroscience, Bd. 22, Nr. 2 [PDF, 6MB]

Suarez-Calvet, Marc; Morenas-Rodriguez, Estrella; Kleinberger, Gernot; Schlepckow, Kai; Caballero, Miguel Angel Araque; Franzmeier, Nicolai; Capell, Anja; Fellerer, Katrin; Nuscher, Brigitte; Eren, Erden; Levin, Johannes; Deming, Yuetiva; Piccio, Laura; Karch, Celeste M.; Cruchaga, Carlos; Shaw, Leslie M.; Trojanowski, John Q.; Weiner, Michael; Ewers, Michael und Haass, Christian (2019): Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid- pathology. In: Molecular Neurodegeneration, Bd. 14, 1 [PDF, 1MB]

Falcon, Caries; Monte-Rubio, Gemma C.; Grau-Rivera, Oriol; Suarez-Calvet, Marc; Sanchez-Valle, Raquel; Rami, Lorena; Bosch, Beatriz; Haass, Christian; Domingo Gispert, Juan und Luis Molinuevo, Jose (2019): CSF glial biomarkers YKL40 and sTREM2 are associated with longitudinal volume and diffusivity changes in cognitively unimpaired individuals. In: Neuroimage-Clinical, Bd. 23, UNSP 101801 [PDF, 2MB]

Haass, Christian und Willem, Michael (2019): Secreted APP Modulates Synaptic Activity: A Novel Target for Therapeutic Intervention? In: Neuron, Bd. 101, Nr. 4: S. 557-559

Zhu, Kaichuan; Xiang, Xianyuan; Filser, Severin; Marinkovic, Petar; Dorostkar, Mario M.; Crux, Sophie; Neumann, Ulf; Shimshek, Derya R.; Rammes, Gerhard; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Lichtenthaler, Stefan F.; Gunnersen, Jenny M. und Herms, Jochen (2018): Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibition Impairs Synaptic Plasticity via Seizure Protein 6. In: Biological Psychiatry, Bd. 83, Nr. 5: S. 428-437

Brendel, Matthias; Yousefi, Behrooz H.; Blume, Tanja; Herz, Michael; Focke, Carola; Deussing, Maximilian; Peters, Finn; Lindner, Simon; Ungern-Sternberg, Barbara von; Drzezga, Alexander; Bartenstein, Peter; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Okamura, Nobuyuki; Herms, Jochen; Yakushev, Igor und Rominger, Axel (2018): Comparison of F-18-T807 and F-18-THK5117 PET in a Mouse Mode of Tau Pathology. In: Frontiers in Aging Neuroscience, Bd. 10, 174 [PDF, 1MB]

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Caballero, Miguel Angel Araque; Suarez-Calvet, Marc; Duering, Marco; Franzmeier, Nicolai; Benzinger, Tammie; Fagan, Anne M.; Bateman, Randall J.; Jack, Clifford R.; Levin, Johannes; Dichgans, Martin ORCID logoORCID: https://orcid.org/0000-0002-0654-387X; Jucker, Mathias; Karch, Celeste; Masters, Colin L.; Morris, John C.; Weiner, Michael; Rossor, Martin; Fox, Nick C.; Lee, Jae-Hong; Salloway, Stephen; Danek, Adrian; Goate, Alison; Yakushev, Igor; Hassenstab, Jason; Schofield, Peter R.; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 und Ewers, Michael (2018): White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer’s disease. In: Brain, Bd. 141: S. 3065-3080

Brendel, Matthias; Jaworska, Anna; Overhoff, Felix; Blume, Tanja; Probst, Federico; Gildehaus, Franz-Josef; Bartenstein, Peter; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Bohrmann, Bernd; Herms, Jochen; Willem, Michael und Rominger, Axel (2018): Efficacy of chronic BACE1 inhibition in PS2APP mice depends on the regional A beta deposition rate and plaque burden at treatment initiation. In: Theranostics, Bd. 8, Nr. 18: S. 4957-4968 [PDF, 3MB]

Suarez-Calvet, Marc; Capell, Anja; Caballero, Miguel Angel Araque; Morenas-Rodriguez, Estrella; Fellerer, Katrin; Franzmeier, Nicolai; Kleinberger, Gernot; Eren, Erden; Deming, Yuetiva; Piccio, Laura; Karch, Celeste M.; Cruchaga, Carlos; Paumier, Katrina; Bateman, Randall J.; Fagan, Anne M.; Morris, John C.; Levin, Johannes; Danek, Adrian; Jucker, Mathias; Masters, Colin L.; Rossor, Martin N.; Ringman, John M.; Shaw, Leslie M.; Trojanowski, John Q.; Weiner, Michael; Ewers, Michael und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2018): CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline. In: EMBO Molecular Medicine, Bd. 10, Nr. 12, e9712

Hong, Wei; Wang, Zemin; Liu, Wen; O'Malley, Tiernan T.; Jin, Ming; Willem, Michael; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Frosch, Matthew P. und Walsh, Dominic M. (2018): Diffusible, highly bioactive oligomers represent a critical minority of soluble A beta in Alzheimer's disease brain. In: Acta Neuropathologica, Bd. 136, Nr. 1: S. 19-40

Xiang, Xianyuan; Piers, Thomas M.; Wefers, Benedikt; Zhu, Kaichuan; Mallach, Anna; Brunner, Bettina; Kleinberger, Gernot; Song, Wilbur; Colonna, Marco; Herms, Jochen; Wurst, Wolfgang; Pocock, Jennifer M. und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2018): The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans. In: Molecular Neurodegeneration 13:49 [PDF, 2MB]

Blauwendraat, Cornelis; Wilke, Carlo; Simon-Sanchez, Javier; Jansen, Iris E.; Reifschneider, Anika; Capell, Anja; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Castillo-Lizardo, Melissa; Biskup, Saskia; Maetzler, Walter; Rizzu, Patrizia; Heutink, Peter und Synofzik, Matthis (2018): The wide genetic landscape of clinical frontotemporal dementia: systematic combined sequencing of 121 consecutive subjects. In: Genetics in Medicine, Bd. 20, Nr. 2: S. 240-249

Götzl, Julia K.; Colombo, Alessio-Vittorio; Fellerer, Katrin; Reifschneider, Anika; Werner, Georg; Tahirovic, Sabina; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 und Capell, Anja (2018): Early lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout mice. In: Molecular Neurodegeneration 13:48 [PDF, 4MB]

Brendel, Matthias; Kleinberger, Gernot; Probst, Federico; Jaworska, Anna; Overhoff, Felix; Blume, Tanja; Albert, Nathalie L.; Carlsen, Janette; Lindner, Simon; Gildehaus, Franz Josef; Ozmen, Laurence; Suarez-Calvet, Marc; Bartenstein, Peter; Baumann, Karlheinz; Ewers, Michael; Herms, Jochen; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 und Rominger, Axel (Januar 2017): Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis. In: Frontiers in aging neuroscience, Bd. 9, 8 [PDF, 2MB]

Mazaheri, Fargol; Snaidero, Nicolas; Kleinberger, Gernot; Madore, Charlotte; Daria, Anna; Werner, Georg; Krasemann, Susanne; Capell, Anja; Trümbach, Dietrich; Wurst, Wolfgang; Brunner, Bettina; Bultmann, Sebastian; Tahirovic, Sabina; Kerschensteiner, Martin; Misgeld, Thomas; Butovsky, Oleg und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2017): TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury. In: Embo Reports, Bd. 18, Nr. 7: S. 1186-1198

Brendel, Matthias; Focke, Carola; Blume, Tanja; Peters, Finn; Deussing, Maximilian; Probst, Federico; Jaworska, Anna; Overhoff, Felix; Albert, Nathalie L. ORCID logoORCID: https://orcid.org/0000-0003-0953-7624; Lindner, Simon; Ungern-Sternberg, Barbara von; Bartenstein, Peter; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Kleinberger, Gernot; Herms, Jochen und Rominger, Axel (2017): Time Courses of Cortical Glucose Metabolism and Microglial Activity Across the Life Span of Wild-Type Mice: A PET Study. In: Journal of Nuclear Medicine, Bd. 58, Nr. 12: S. 1984-1990

Schlepckow, Kai; Kleinberger, Gernot; Fukumori, Akio; Feederle, Regina; Lichtenthaler, Stefan F.; Steiner, Harald und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2017): An Alzheimer-associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function. In: Embo Molecular Medicine, Bd. 9, Nr. 10: S. 1356-1365 [PDF, 1MB]

Kleinberger, Gernot; Brendel, Matthias; Mracsko, Eva; Wefers, Benedikt; Groeneweg, Linda; Xiang, Xianyuan; Focke, Carola; Deußing, Maximilian; Suarez-Calvet, Marc; Mazaheri, Fargol; Parhizkar, Samira; Pettkus, Nadine; Wurst, Wolfgang; Feederle, Regina; Bartenstein, Peter; Mueggler, Thomas; Arzberger, Thomas; Knuesel, Irene; Rominger, Axel und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2017): The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism. In: Embo Journal, Bd. 36, Nr. 13: S. 1837-1853

Daria, Anna; Colombo, Alessio; Llovera, Gemma; Hampel, Heike; Willem, Michael; Liesz, Arthur; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 und Tahirovic, Sabina (2017): Young microglia restore amyloid plaque clearance of aged microglia. In: Embo Journal, Bd. 36, Nr. 5: S. 583-603

Scekic-Zahirovic, Jelena; El Oussini, Hajer; Mersmann, Sina; Drenner, Kevin; Wagner, Marina; Sun, Ying; Allmeroth, Kira; Dieterle, Stephane; Sinniger, Jerome; Dirrig-Grosch, Sylvie; Rene, Frederique; Dormann, Dorothee; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Ludolph, Albert C.; Lagier-Tourenne, Clotilde; Storkebaum, Erik und Dupuis, Luc (2017): Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis. In: Acta Neuropathologica, Bd. 133, Nr. 6: S. 887-906

Zhou, Qihui; Lehmer, Carina; Michaelsen, Meike; Mori, Kohji; Alterauge, Dominik; Baumjohann, Dirk; Schludi, Martin H.; Greiling, Johanna; Farny, Daniel; Flatley, Andrew; Feederle, Regina; May, Stephanie; Schreiber, Franziska; Arzberger, Thomas; Kuhm, Christoph; Klopstock, Thomas; Hermann, Andreas; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 und Edbauer, Dieter (2017): Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteins. In: Embo Molecular Medicine, Bd. 9, Nr. 5: S. 687-702

Davidson, Yvonne S.; Flood, Louis; Robinson, Andrew C.; Nihei, Yoshihiro; Mori, Kohji; Rollinson, Sara; Richardson, Anna; Benson, Bridget C.; Jones, Matthew; Snowden, Julie S.; Pickering-Brown, Stuart; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Lashley, Tammaryn und Mann, David M. A. (2017): Heterogeneous ribonuclear protein A3 (hnRNP A3) is present in dipeptide repeat protein containing inclusions in Frontotemporal Lobar Degeneration and Motor Neurone disease associated with expansions in C9orf72 gene. In: Acta Neuropathologica Communications 5:31 [PDF, 1MB]

Krasemann, Susanne; Madore, Charlotte; Cialic, Ron; Baufeld, Caroline; Calcagno, Narghes; El Fatimy, Rachid; Beckers, Lien; O'Loughlin, Elaine; Xu, Yang; Fanek, Zain; Greco, David J.; Smith, Scott T.; Tweet, George; Humulock, Zachary; Zrzavy, Tobias; Conde-Sanroman, Patricia; Gacias, Mar; Weng, Zhiping; Chen, Hao; Tjon, Emily; Mazaheri, Fargol; Hartmann, Kristin; Madi, Asaf; Ulrich, Jason D.; Glatzel, Markus; Worthmann, Anna; Heeren, Jörg; Budnik, Bogdan; Lemere, Cynthia; Ikezu, Tsuneya; Heppner, Frank L.; Litvak, Vladimir; Holtzman, David M.; Lassmann, Hans; Weiner, Howard L.; Ochando, Jordi; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 und Butovsky, Oleg (2017): The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases. In: Immunity, Bd. 47, Nr. 3: S. 566-581

Ohki, Yu; Wenninger-Weinzierl, Andrea; Hruscha, Alexander; Asakawa, Kazuhide; Kawakami, Koichi; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Edbauer, Dieter und Schmid, Bettina (2017): Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model of C9orf72 associated neurodegeneration. In: Molecular Neurodegeneration 12:6 [PDF, 1MB]

Suarez-Calvet, Marc; Kleinberger, Gernot; Araque Caballero, Miguel Angel; Brendel, Matthias; Rominger, Axel; Alcolea, Daniel; Fortea, Juan; Lleo, Alberto; Blesa, Rafael; Gispert, Juan Domingo; Sanchez-Valle, Raquel; Antonell, Anna; Rami, Lorena; Molinuevo, Jose L.; Brosseron, Frederic; Traschutz, Andreas; Heneka, Michael T.; Struyfs, Hanne; Engelborghs, Sebastiaan; Sleegers, Kristel; Broeckhoven, Christine van; Zetterberg, Henrik; Nellgard, Bengt; Blennow, Kaj; Crispin, Alexander; Ewers, Michael und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2016): sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers. In: EMBO Molecular Medicine, Bd. 8, Nr. 5: S. 466-476

Xiang, Xianyuan; Werner, Georg; Bohrmann, Bernd; Liesz, Arthur; Mazaheri, Fargol; Capell, Anja; Feederle, Regina; Knuesel, Irene; Kleinberger, Gernot und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2016): TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance. In: Embo Molecular Medicine, Bd. 8, Nr. 9: S. 992-1004 [PDF, 1MB]

Kretner, Benedikt; Trambauer, Johannes; Fukumori, Akio; Mielke, Janina; Kuhn, Peer-Hendrik; Kremmer, Elisabeth; Giese, Armin; Lichtenthaler, Stefan F.; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Arzberger, Thomas und Steiner, Harald (2016): Generation and deposition of A43 by the virtually inactive presenilin-1 L435F mutant contradicts the presenilin loss-of-function hypothesis of Alzheimer's disease. In: Embo Molecular Medicine, Bd. 8, Nr. 5: S. 458-465 [PDF, 1MB]

Ben Halima, Saoussen; Mishra, Sabyashachi; Raja, K. Muruga Poopathi; Willem, Michael; Baici, Antonio; Simons, Kai; Bruestle, Oliver; Koch, Philipp; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Caflisch, Amedeo und Rajendran, Lawrence (2016): Specific Inhibition of beta-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein. In: Cell Reports, Bd. 14, Nr. 9: S. 2127-2141 [PDF, 13MB]

Overhoff, Felix; Brendel, Matthias; Jaworska, Anna; Korzhova, Viktoria; Delker, Andreas; Probst, Federico; Focke, Carola; Gildehaus, Franz-Josef; Carlsen, Janette; Baumann, Karlheinz; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Bartenstein, Peter; Herms, Jochen und Rominger, Axel (2016): Automated Spatial Brain Normalization and Hindbrain White Matter Reference Tissue Give Improved [F-18]-Florbetaben PET Quantitation in Alzheimer's Model Mice. In: Frontiers in Neuroscience, Bd. 10, 45 [PDF, 2MB]

Suárez-Calvet, Marc; Caballero, Miguel Ángel Araque; Kleinberger, Gernot; Bateman, Randall J.; Fagan, Anne M.; Morris, John C.; Levin, Johannes; Danek, Adrian; Ewers, Michael und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2016): Early changes in CSF sTREM2 in dominantly inherited Alzheimer's disease occur after amyloid deposition and neuronal injury. In: Science Translational Medicine, Bd. 8, Nr. 369, 369ra178

Mori, Kohji; Nihei, Yoshihiro; Arzberger, Thomas; Zhou, Qihui; Mackenzie, Ian R.; Hermann, Andreas; Hanisch, Frank; Kamp, Frits; Nuscher, Brigitte; Orozco, Denise; Edbauer, Dieter und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2016): Reduced hnRNPA3 increases C9orf72 repeat RNA levels and dipeptide-repeat protein deposition. In: Embo Reports, Bd. 17, Nr. 9: S. 1314-1325

Kretner, Benedikt; Trambauer, Johannes; Fukumori, Akio; Mielke, Janina; Kuhn, Peer-Hendrik; Kremmer, Elisabeth; Giese, Armin; Lichtenthaler, Stefan F.; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Arzberger, Thomas und Steiner, Harald (2016): Generation and deposition of A43 by the virtually inactive presenilin-1 L435F mutant contradicts the presenilin loss-of-function hypothesis of Alzheimer's disease. In: Embo Molecular Medicine, Bd. 8, Nr. 5: S. 458-465

Fleck, Daniel; Voss, Matthias; Brankatschk, Ben; Giudici, Camilla; Hampel, Heike; Schwenk, Benjamin; Edbauer, Dieter; Fukumori, Akio; Steiner, Harald; Kremmer, Elisabeth; Haug-Kröper, Martina; Rossner, Moritz J.; Fluhrer, Regina; Willem, Michael und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2016): Proteolytic Processing of Neuregulin 1 Type III by Three Intramembrane-cleaving Proteases. In: Journal of Biological Chemistry, Bd. 291, Nr. 1: S. 318-333

Edbauer, Dieter und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2016): An amyloid-like cascade hypothesis for C9orf72 ALS/FTD. In: Current Opinion in Neurobiology, Bd. 36: S. 99-106

Götzl, Julia K.; Lang, Christina M.; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 und Capell, Anja (2016): Impaired protein degradation in FTLD and related disorders. In: Ageing Research Reviews, Bd. 32: S. 122-139

Gispert, Juan Domingo; Suárez-Calvet, Marc; Monté, Gemma C.; Tucholka, Alan; Falcon, Caries; Rojas, Santiago; Rami, Lorena; Sanchez-Valle, Raquel; Lladó, Albert; Kleinberger, Gemot; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 und Molinuevo, José Luis (2016): Cerebrospinal fluid sTREM2 levels are associated with gray matter volume increases and reduced diffusivity in early Alzheimer's disease. In: Alzheimers & Dementia, Bd. 12, Nr. 12: S. 1259-1272

Kleinberger, Gernot; Capell, Anja; Brouwers, Nathalie; Fellerer, Katrin; Sleegers, Kristel; Cruts, Marc; Broeckhoven, Christine van und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2016): Reduced secretion and altered proteolytic processing caused by missense mutations in progranulin. In: Neurobiology of Aging, Bd. 39, 220.e17

Eichner, Ruth; Heider, Michael; Fernández-Sáiz, Vanesa; Bebber, Frauke van; Garz, Anne-Kathrin; Lemeer, Simone; Rudelius, Martina; Targosz, Bianca-Sabrina; Jacobs, Laura; Knorn, Anna-Maria; Slawska, Jolanta; Platzbecker, Uwe; Germing, Ulrich; Langer, Christian; Knop, Stefan; Einsele, Herrmann; Peschel, Christian; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Keller, Ulrich; Schmid, Bettina; Götze, Katharina S.; Kuster, Bernhard und Bassermann, Florian (2016): Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity. In: Nature Medicine, Bd. 22, Nr. 7: S. 735-743

Halder, Rashi; Hennion, Magali; Vidal, Ramon O.; Shomroni, Orr; Rahman, Raza-Ur; Rajput, Ashish; Centeno, Tonatiuh Pena; Bebber, Frauke van; Capece, Vincenzo; Vizcaino, Julio C. Garcia; Schuetz, Anna-Lena; Burkhardt, Susanne; Benito, Eva; Sala, Magdalena Navarro; Javan, Sanaz Bahari; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Schmid, Bettina; Fischer, Andre und Bonn, Stefan (2016): DNA methylation changes in plasticity genes accompany the formation and maintenance of memory. In: Nature Neuroscience, Bd. 19, Nr. 1: S. 102-110

Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 und Neumann, Manuela (2016): Frontotemporal dementias: From molecular mechanisms to therapy PREFACE. In: Journal of Neurochemistry, Bd. 138: S. 3-5

Brendel, Matthias; Jaworska, Anna; Probst, Federico; Overhoff, Felix; Korzhova, Viktoria; Lindner, Simon; Carlsen, Janette; Bartenstein, Peter; Harada, Ryuichi; Kudo, Yukitsuka; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Leuven, Fred van; Okamura, Nobuyuki; Herms, Jochen und Rominger, Axel (2016): Small-Animal PET Imaging of Tau Pathology with F-18-THK5117 in 2 Transgenic Mouse Models. In: Journal of Nuclear Medicine, Bd. 57, Nr. 5: S. 792-798

Brendel, Matthias; Probst, Federico; Jaworska, Anna; Overhoff, Felix; Korzhova, Viktoria; Albert, Nathalie L.; Beck, Roswitha; Lindner, Simon; Gildehaus, Franz-Josef; Baumann, Karlheinz; Bartenstein, Peter; Kleinberger, Gernot; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Herms, Jochen und Rominger, Axel (2016): Glial Activation and Glucose Metabolism in a Transgenic Amyloid Mouse Model: A Triple-Tracer PET Study. In: Journal of Nuclear Medicine, Bd. 57, Nr. 6: S. 954-960

Suárez-Calvet, Marc; Neumann, Manuela; Arzberger, Thomas; Abou-Ajram, Claudia; Funk, Eva; Hartmann, Hannelore; Edbauer, Dieter; Kremmer, Elisabeth; Göbl, Christoph; Resch, Moritz; Bourgeois, Benjamin; Madl, Tobias; Reber, Stefan; Jutzi, Daniel; Ruepp, Marc-David; Mackenzie, Ian R. A.; Ansorge, Olaf; Dormann, Dorothee und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2016): Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS. In: Acta Neuropathologica, Bd. 131, Nr. 4: S. 587-604

Janssens, Jonathan; Philtjens, Stephanie; Kleinberger, Gernot; Mossevelde, Sara van; Zee, Julie van der; Cacace, Rita; Engelborghs, Sebastiaan; Sieben, Anne; Banzhaf-Strathmann, Julia; Dillen, Lubina; Merlin, Celine; Cuijt, Ivy; Robberecht, Caroline; Schmid, Bettina; Santens, Patrick; Ivanoiu, Adrian; Vandenbulcke, Mathieu; Vandenberghe, Rik; Cras, Patrick; De Deyn, Peter P.; Martin, Jean-Jacques; Maudsley, Stuart; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Cruts, Marc und Broeckhoven, Christine van (2015): Investigating the role of filamin C in Belgian patients with frontotemporal dementia linked to GRN deficiency in FTLD-TDP brains. In: Acta Neuropathologica Communications 3:68 [PDF, 3MB]

Solchenberger, Barbara; Russell, Claire; Kremmer, Elisabeth; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 und Schmid, Bettina (2015): Granulin Knock Out Zebrafish Lack Frontotemporal Lobar Degeneration and Neuronal Ceroid Lipofuscinosis Pathology.
In: PLOS ONE 10(3), e0118956 [PDF, 3MB]

Brendel, Matthias; Jaworska, Anna; Grieinger, Eric; Rötzer, Christina; Burgold, Steffen; Gildehaus, Franz-Josef; Carlsen, Janette; Cumming, Paul; Baumann, Karlheinz; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Steiner, Harald; Bartenstein, Peter; Herms, Jochen und Rominger, Axel (2015): Cross-Sectional Comparison of Small Animal [F-18]-Florbetaben Amyloid-PET between Transgenic AD Mouse Models.
In: PLOS ONE 10(2), e0116678 [PDF, 1MB]

Kragh, Christine L.; Fillon, Gwenaëlle; Gysbers, Amanda; Hansen, Hanne D.; Neumann, Manuela; Richter-Landsberg, Christiane; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Zalc, Bernard; Lubetzki, Catherine; Gai, Wei-Ping; Halliday, Glenda M.; Kahle, Philipp J. und Jensen, Poul H. (2013): FAS-dependent cell death in α-synuclein transgenic oligodendrocyte models of multiple system atrophy.
In: PLOS ONE 8(1), e55243 [PDF, 849kB]

Fluhrer, Regina; Kamp, Frits; Grammer, Gudula; Nuscher, Brigitte; Steiner, Harald; Beyer, Klaus und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2011): The Nicastrin ectodomain adopts a highly thermostable structure. In: Biological Chemistry, Bd. 392, Nr. 11: S. 995-1001 [PDF, 1MB]

Fett, Mareike E.; Pilsl, Anna; Paquet, Dominik; Bebber, Frauke van; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Tatzelt, Jörg; Schmid, Bettina und Winklhofer, Konstanze F. (30. Juli 2010): Parkin is protective against proteotoxic stress in a transgenic zebrafish model.
In: PLOS ONE 5(7), e11783 [PDF, 3MB]

Paquet, Dominik; Schmid, Bettina und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2010): Transgenic Zebrafish as a Novel Animal Model to Study Tauopathies and Other Neurodegenerative Disorders in vivo. In: Neurodegenerative Diseases, Nr. 1-3, S: S. 99-102 [PDF, 100kB]

Fournier, Margot; Vitte, Jérémie; Garrigue, Jérôme; Langui, Dominique; Dullin, Jean-Philippe; Saurini, Françoise; Hanoun, Naïma; Perez-Diaz, Fernando; Cornilleau, Fabien; Joubert, Chantal; Ardila-Osorio, Héctor; Traver, Sabine; Duchateau, René; Goujet-Zalc, Cécile; Paleologou, Katerina; Lashuel, Hilal A.; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Duyckaerts, Charles; Cohen-Salmon, Charles; Kahle, Philipp J.; Hamon, Michel; Brice, Alexis und Corti, Olga (2009): Parkin deficiency delays motor decline and disease manifestation in a mouse model of synucleinopathy.
In: PLOS ONE 4(8), e6629 [PDF, 2MB]

Itoh, Naohiro; Okochi, Masayasu; Tagami, Shinji; Nishitomi, Kouhei; Nakayama, Taisuke; Yanagida, Kanta; Fukumori, Akio; Jiang, Jingwei; Mori, Kohji; Hosono, Motoko; Kikuchi, Jyunko; Nakano, Yuko; Takinami, Yoshihiko; Dohi, Keiji; Nishigaki, Atsuko; Takemoto, Hiroshi; Minagawa, Kazuyuki; Katoh, Takaaki; Willem, Michael; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Morihara, Takashi; Tanaka, Toshihisa; Kudo, Takashi; Hasegawa, Hiroshi; Nishimura, Masaki; Sakaguchi, Gaku; Kato, Akira und Takeda, Masatoshi (2009): Destruxin E Decreases Beta-Amyloid Generation by Reducing Colocalization of Beta-Amyloid-Cleaving Enzyme 1 and Beta-Amyloid Protein Precursor. In: Neurodegenerative Diseases, Nr. 5-6: S. 230-239 [PDF, 556kB]

Fluhrer, Regina und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2007): Signal peptide peptidases and gamma-secretase: Cousins of the same protease family? In: Neurodegenerative Diseases, Nr. 2-3: S. 112-116 [PDF, 214kB]

Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 und Multhaup, Gerd (2006): Six years of collaborative Alzheimer's disease research in Germany. In: Neurodegenerative Diseases, Nr. 4-5: S. 193-196 [PDF, 904kB]

Kaether, Christoph; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 und Steiner, Harald (2006): Assembly, trafficking and function of gamma-secretase. In: Neurodegenerative Diseases, Nr. 4-5: S. 275-283 [PDF, 402kB]

Haffner, Christof und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2006): Cellular functions of gamma-secretase-related proteins. In: Neurodegenerative Diseases, Nr. 4-5: S. 284-289 [PDF, 423kB]

Haffner, Christof und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2004): The Biochemical and Genetic Odyssey to the Function of a Nicastrin-Like Protein. In: Neurodegenerative Diseases, Nr. 4-5: S. 192-195 [PDF, 194kB]

Zeitungsartikel

Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 und Sewald, Bettina (19. Dezember 2020): Weder Gans noch Rotwein schmecken. In: Münchner Merkur Ausgabe Geretsrieder Merkur, Nr. 294: S. 4

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