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Veröffentlichungsdatum
Anzahl der Publikationen: 28
2024
Hoelscher, Michael 
ORCID: https://orcid.org/0000-0002-7642-1835; Barros-Aguirre, David; Dara, Masoud; Heinrich, Norbert; Sun, Eugene; Lange, Christoph; Tiberi, Simon und Wells, Charles
(2024):
Candidate anti-tuberculosis medicines and regimens under clinical evaluation.
In: Clinical Microbiology and Infection [Forthcoming]
ORCID: https://orcid.org/0000-0002-7642-1835; Barros-Aguirre, David; Dara, Masoud; Heinrich, Norbert; Sun, Eugene; Lange, Christoph; Tiberi, Simon und Wells, Charles
(2024):
Candidate anti-tuberculosis medicines and regimens under clinical evaluation.
In: Clinical Microbiology and Infection [Forthcoming]
2022
Azam, Khalide; Khosa, Celso; Viegas, Sofia; Massango, Isabel; Bhatt, Nilesh; Jani, Ilesh; Heinrich, Norbert; Hoelscher, Michael; Gillespie, Stephen H.; Rachow, Andrea und Sabiiti, Wilber
(2022):
Reduction of blood C-reactive protein concentration complements the resolution of sputum bacillary load in patients on anti-tuberculosis therapy.
In: Frontiers in Immunology, Bd. 13, 1005692
Mutayoba, Beatrice Kemilembe; Hoelscher, Michael; Heinrich, Norbert; Joloba, Moses L.; Lyamuya, Eligius; Kilale, Andrew Martin; Range, Nyagosya Segere; Ngowi, Bernard James; Ntinginya, Nyanda Elias; Mfaume, Saidi Mwinjuma; Wilfred, Amani; Doulla, Basra; Lyimo, Johnson; Kisonga, Riziki; Kingalu, Amri; Kabahita, Jupiter Marina; Guido, Ocung; Kabugo, Joel; Adam, Isa; Luutu, Moses; Namaganda, Maria Magdalene; Namutebi, Joanitah; Kasule, George William; Nakato, Hasfah; Byabajungu, Henry; Lutaaya, Pius; Musisi, Kenneth; Oola, Denis; Mboowa, Gerald und Pletschette, Michel
(2022):
Phylogenetic lineages of tuberculosis isolates and their association with patient demographics in Tanzania.
In: BMC Genomics, Bd. 23, Nr. 1, 561
Heyckendorf, Jan; Georghiou, Sophia B.; Frahm, Nicole; Heinrich, Norbert; Kontsevaya, Irina; Reimann, Maja; Holtzman, David; Imperial, Marjorie; Cirillo, Daniela M.; Gillespie, Stephen H. und Ruhwald, Morten
(2022):
Tuberculosis Treatment Monitoring and Outcome Measures: New Interest and New Strategies.
In: Clinical Microbiology Reviews, Bd. 35, Nr. 3, e00227-21
Mutayoba, Beatrice Kemilembe; Ershova, Julia; Lyamuya, Eligius; Hölscher, Michael; Heinrich, Norbert; Kilale, Andrew Martin; Range, Nyagosya Segere; Ngowi, Benard James; Ntinginya, Nyanda Elias; Mfaume, Saidi Mwinjuma; Nkiligi, Emmanuel; Doulla, Basra; Lyimo, Johnson; Kisonga, Riziki; Kingalu, Amri; Lema, Yakobo; Kondo, Zuwena und Pletschette, Michel
(2022):
The second national anti-tuberculosis drug resistance survey in Tanzania, 2017-2018.
In: Tropical Medicine & International Health, Bd. 27, Nr. 10: S. 891-901
Marambire, Edson Tawanda ORCID: https://orcid.org/0000-0001-5944-5010; Banze, Denise; Mfinanga, Alfred; Mutsvangwa, Junior; Mbunda, Theodora D.; Ntinginya, Nyanda Elias; Celso, Khosa; Kallenius, Gunilla; Calderwood, Claire J.; Geldmacher, Christof; Held, Kathrin; Appalarowthu, Tejaswi; Rieß, Friedrich; Panzner, Ursula; Heinrich, Norbert und Kranzer, Katharina
(2022):
Early risk assessment in paediatric and adult household contacts of confirmed tuberculosis cases by novel diagnostic tests (ERASE-TB): protocol for a prospective, non-interventional, longitudinal, multicountry cohort study.
In: BMJ Open, Bd. 12, Nr. 7, e060985
[PDF, 4MB]
ORCID: https://orcid.org/0000-0001-5944-5010; Banze, Denise; Mfinanga, Alfred; Mutsvangwa, Junior; Mbunda, Theodora D.; Ntinginya, Nyanda Elias; Celso, Khosa; Kallenius, Gunilla; Calderwood, Claire J.; Geldmacher, Christof; Held, Kathrin; Appalarowthu, Tejaswi; Rieß, Friedrich; Panzner, Ursula; Heinrich, Norbert und Kranzer, Katharina
(2022):
Early risk assessment in paediatric and adult household contacts of confirmed tuberculosis cases by novel diagnostic tests (ERASE-TB): protocol for a prospective, non-interventional, longitudinal, multicountry cohort study.
In: BMJ Open, Bd. 12, Nr. 7, e060985
[PDF, 4MB]
2021
Zhang, Nan; Savic, Radojka M.; Boeree, Martin J.; Peloquin, Charles A.; Weiner, Marc; Heinrich, Norbert; Bliven-Sizemore, Erin; Phillips, Patrick P. J.; Hoelscher, Michael; Whitworth, William; Morlock, Glenn; Posey, James; Stout, Jason E.; Mac Kenzie, William; Aarnoutse, Robert und Dooley, Kelly E.
(2021):
Optimising pyrazinamide for the treatment of tuberculosis.
In: European Respiratory Journal, Bd. 58, Nr. 1, 2002013
Ihling, Clara Marlene; Schnitzler, Paul; Heinrich, Norbert; Mangu, Chacha; Sudi, Lwitiho; Souares, Aurelia; Gies, Sabine; Sie, Ali; Coulibaly, Boubacar; Ouedraogo, Andiyam Thierry; Mordmueller, Benjamin; Held, Jana; Adegnika, Ayola Akim; Fernandes, Jose F.; Eckerle, Isabella; May, Jürgen; Hogan, Benedikt; Eibach, Daniel und Tabatabai, Julia
(2021):
Molecular epidemiology of respiratory syncytial virus in children in sub-Saharan Africa.
In: Tropical Medicine & International Health, Bd. 26, Nr. 7: S. 810-822
Brake, Lindsey H. M. te; de Jager, Veronique; Narunsky, Kim; Vanker, Naadira; Svensson, Elin M.; Phillips, Patrick P. J.; Gillespie, Stephen H.; Heinrich, Norbert; Hoelscher, Michael; Dawson, Rodney; Diacon, Andreas H.; Aamoutse, Rob E. und Boeree, Martin J.
(2021):
Increased bactericidal activity but dose-limiting intolerability at 50 mg.kg(-1) rifampicin.
In: European Respiratory Journal, Bd. 58, Nr. 1, 2000955
2020
Moirongo, Rehema Moraa; Lorenz, Eva; Ntinginya, Nyanda E.; Dekker, Denise; Fernandes, Jose; Held, Jana; Lamshoeft, Maike; Schaumburg, Frieder; Mangu, Chacha; Sudi, Lwitiho; Sie, Ali; Souares, Aurelia; Heinrich, Norbert; Wieser, Andreas; Mordmueller, Benjamin; Owusu-Dabo, Ellis; Adegnika, Akim Ayola; Coulibaly, Boubacar; May, Jürgen und Eibach, Daniel
(25. September 2020):
Regional Variation of Extended-Spectrum Beta-Lactamase (ESBL)-Producing Enterobacterales, Fluoroquinolone-ResistantSalmonella entericaand Methicillin-ResistantStaphylococcus aureusAmong Febrile Patients in Sub-Saharan Africa.
In: Frontiers in Microbiology, Bd. 11, 567235: S. 1-10
[PDF, 209kB]
Beutler, Markus; Plesnik, Sara; Mihalic, Marina; Olbrich, Laura; Heinrich, Norbert; Schumacher, Samuel; Lindner, Michael; Koch, Ina; Grasse, Wolfgang; Metzger-Boddien, Christoph; Hofmann-Thiel, Sabine und Hoffmann, Harald
(2020):
A pre-clinical validation plan to evaluate analytical sensitivities of molecular diagnostics such as BD MAX MDR-TB, Xpert MTB/Rif Ultra and FluoroType MTB.
In: PLOS One 15(1), e0227215 [PDF, 966kB]
In: PLOS One 15(1), e0227215 [PDF, 966kB]
Sabiiti, Wilber; Azam, Khalide; Farmer, Eoghan Charles William; Kuchaka, Davis; Mtafya, Bariki; Bowness, Ruth; Oravcova, Katarina; Honeyborne, Isobella; Evangelopoulos, Dimitrios; McHugh, Timothy Daniel; Khosa, Celso; Rachow, Andrea; Heinrich, Norbert; Kampira, Elizabeth; Davies, Geraint; Bhatt, Nilesh; Ntinginya, Elias N.; Viegas, Sofia; Jani, Ilesh; Kamdolozi, Mercy; Mdolo, Aaron; Khonga, Margaret; Boeree, Martin J.; Phillips, Patrick P. J.; Sloan, Derek; Hoelscher, Michael; Kibiki, Gibson und Gillespie, Stephen H.
(2020):
Tuberculosis bacillary load, an early marker of disease severity: the utility of tuberculosis Molecular Bacterial Load Assay.
In: Thorax, Bd. 75, Nr. 7: S. 606-608
[PDF, 703kB]
2019
Abdiyeva, Karlygash; Turebekov, Nurkeldi; Dmitrovsky, Andrey; Tukhanova, Nur; Shin, Anna; Yeraliyeva, Lyazat; Heinrich, Norbert; Hoelscher, Michael; Yegemberdiyeva, Ravilya; Shapiyeva, Zhanna; Kachiyeva, Zulfiya; Zhalmagambetova, Aliya; Montag, Josef; Dobler, Gerhard; Zinner, Josua; Wagner, Edith; Frey, Stefan und Essbauer, Sandra
(2019):
Seroepidemiological and molecular investigations of infections with Crimean-Congo haemorrhagic fever virus in Kazakhstan.
In: International Journal of Infectious Diseases, Bd. 78: S. 121-127
2018
Ahmed, Mohamed I. M.; Ntinginya, Nyanda E.; Kibiki, Gibson; Mtafya, Bariki A.; Semvua, Hadija; Mpagama, Stellah; Mtabho, Charles; Saathoff, Elmar; Held, Kathrin; Loose, Rebecca; Kroidl, Inge; Chachage, Mkunde; Both, Ulrich von; Haule, Antelmo; Mekota, Anna-Maria; Böree, Martin J.; Gillespie, Stephen H.; Hoelscher, Michael; Heinrich, Norbert und Geldmacher, Christof
(2018):
Phenotypic Changes on Mycobacterium Tuberculosis-Specific CD4 T Cells as Surrogate Markers for Tuberculosis Treatment Efficacy.
In: Frontiers in Immunology, Bd. 9, 2247
[PDF, 4MB]
Svensson, Elin M.; Svensson, Robin J.; te Brake, Lindsey H. M.; Böree, Martin J.; Heinrich, Norbert; Konsten, Sarah; Churchyard, Gavin; Dawson, Rodney; Diacon, Andreas H.; Kibiki, Gibson S.; Minja, Lilian T.; Ntingiya, Nyanda E.; Saone, Ian; Gillespie, Stephen H.; Hölscher, Michael; Phillips, Patrick P. J.; Simonsson, Ulrika S. H. und Aarnoutse, Rob
(2018):
The Potential for Treatment Shortening With Higher Rifampicin Doses: Relating Drug Exposure to Treatment Response in Patients With Pulmonary Tuberculosis.
In: Clinical Infectious Diseases, Bd. 67, Nr. 1: S. 34-41
Rachow, Andrea; Saathoff, Elmar; Mtafya, Bariki; Mapamba, Daniel; Mangu, Chacha; Rojas-Ponce, Gabriel; Ntinginya, Nyanda E.; Böree, Martin; Heinrich, Norbert; Gillespie, Stephen H. und Hölscher, Michael
(2018):
The impact of repeated NALC/NaOH- decontamination on the performance of Xpert MTB/RIF assay.
In: Tuberculosis, Bd. 110: S. 56-58
2017
Dittrich, Sabine; Tadesse, Birkneh T.; Moussy, Francis; Chua, Arlene; Zorzet, Anna; Tangden, Thomas; Dolinger, David L.; Page, Anne-Laure; Crump, John A.; Valerie, D'Acremont; Bassat, Quique; Lubell, Yoel; Heinrich, Norbert; Newton, Paul N.; Rodwell, Tim und Gonzalez, Iveth J.
(2017):
Target Product Profile for a Diagnostic Assay to Differentiate Between Bacterial and Non-Bacterial Infections to Guide Antimicrobials Use in Resource-Limited Settings: An Expert Consensus.
In: American Journal of Tropical Medicine and Hygiene, Bd. 95, Nr. 5: S. 527
Boeree, Martin J.; Heinrich, Norbert; Aarnoutse, Rob; Diacon, Andreas H.; Dawson, Rodney; Rehal, Sunita; Kibiki, Gibson S.; Churchyard, Gavin; Sanne, Ian; Ntinginya, Nyanda E.; Minja, Lilian T.; Hunt, Robert D.; Charalambous, Salome; Hanekom, Madeleine; Semvua, Hadija H.; Mpagama, Stellah G.; Manyama, Christina; Mtafya, Bariki; Reither, Klaus; Wallis, Robert S.; Venter, Amour; Narunsky, Kim; Mekota, Anka; Henne, Sonja; Colbers, Angela; Plemper van Balen, Georgette; Gillespie, Stephen H.; Phillips, Patrick P. J. und Hölscher, Michael
(2017):
High-dose rifampicin, moxifloxacin, and SQ109 for treating tuberculosis: a multi-arm, multi-stage randomised controlled trial.
In: Lancet infectious Diseases, Bd. 17, Nr. 1: S. 39-49
2016
Pohl, Christian; Rutaihwa, Liliana K.; Haraka, Frederick; Nsubuga, Martin; Aloi, Francesco; Ntinginya, Nyanda E.; Mapamba, Daniel; Heinrich, Norbert; Hölscher, Michael; Marais, Ben J.; Jugheli, Levan und Reither, Klaus
(2016):
Limited value of whole blood Xpert (R) MTB/RIF for diagnosing tuberculosis in children.
In: Journal of infection, Bd. 73, Nr. 4: S. 326-335
Froeschl, Guenter; Ntinginya, Nyanda Elias; Sangare, Anthony; Lawala, Paul; Mangu, Chacha; Dobler, Gerhard; Heinrich, Norbert; Flach, Britta; Nsojo, Anthony und Lennemann, Tessa
(2016):
Integrating Local, National, and International Stakeholders in Outbreak Preparedness in Developing Countries: Conclusions from a Conference in Mbeya, Tanzania.
In: Health Security, Bd. 14, Nr. 1: S. 29-34
Phillips, Patrick P. J.; Dooley, Kelly E.; Gillespie, Stephen H.; Heinrich, Norbert; Stout, Jason E.; Nahid, Payam; Diacon, Andreas H.; Aarnoutse, Rob E.; Kibiki, Gibson S.; Boeree, Martin J. und Hoelscher, Michael
(2016):
A new trial design to accelerate tuberculosis drug development: the Phase IIC Selection Trial with Extended Post-treatment follow-up (STEP).
In: BMC Medicine
14:51
[PDF, 2MB]
Dittrich, Sabine; Tadesse, Birkneh Tilahun; Moussy, Francis; Chua, Arlene; Zorzet, Anna; Tängdén, Thomas; Dolinger, David L.; Page, Anne-Laure; Crump, John A.; D'Acremont, Valerie; Bassat, Quique; Lubell, Yoel; Newton, Paul N.; Heinrich, Norbert; Rodwell, Timothy J. und González, Iveth J.
(2016):
Target Product Profile for a Diagnostic Assay to Differentiate between Bacterial and Non-Bacterial Infections and Reduce Antimicrobial Overuse in Resource-Limited Settings: An Expert Consensus.
In: PLOS ONE 11(8), e0161721 [PDF, 245kB]
In: PLOS ONE 11(8), e0161721 [PDF, 245kB]
Ali, Solomon; Beckert, Patrick; Haileamlak, Abraham; Wieser, Andreas; Pritsch, Michael; Heinrich, Norbert; Löscher, Thomas; Hoelscher, Michael; Niemann, Stefan und Rachow, Andrea
(2016):
Drug resistance and population structure of M-tuberculosis isolates from prisons and communities in Ethiopia.
In: BMC infectious Diseases
16:687
[PDF, 1MB]
2015
Heinrich, Norbert; Dill, Tatjana; Dobler, Gerhard; Clowes, Petra; Kroidl, Inge; Starke, Mandy; Ntinginya, Nyanda Elias; Maboko, Leonard; Loescher, Thomas; Hoelscher, Michael und Saathoff, Elmar
(2015):
High Seroprevalence for Spotted Fever Group Rickettsiae, Is Associated with Higher Temperatures and Rural Environment in Mbeya Region, Southwestern Tanzania.
In: PLOS Neglected Tropical Diseases 9(4), e0003626 [PDF, 1MB]
In: PLOS Neglected Tropical Diseases 9(4), e0003626 [PDF, 1MB]
Ali, Solomon; Haileamlak, Abraham; Wieser, Andreas; Pritsch, Michael; Heinrich, Norbert; Loscher, Thomas; Hoelscher, Michael und Rachow, Andrea
(2015):
Prevalence of Pulmonary Tuberculosis among Prison Inmates in Ethiopia, a Cross-Sectional Study.
In: PLOS ONE 10(12), e0144040 [PDF, 267kB]
In: PLOS ONE 10(12), e0144040 [PDF, 267kB]
2014
Weller, Nina; Clowes, Petra; Dobler, Gerhard; Saathoff, Elmar; Kroidl, Inge; Ntinginya, Nyanda Elias; Maboko, Leonard; Löscher, Thomas; Hoelscher, Michael und Heinrich, Norbert
(2014):
Seroprevalence of Alphavirus Antibodies in a Cross-Sectional Study in Southwestern Tanzania Suggests Endemic Circulation of Chikungunya.
In: PLOS Neglected Tropical Diseases 8(7), e2979 [PDF, 606kB]
In: PLOS Neglected Tropical Diseases 8(7), e2979 [PDF, 606kB]
2012
Heinrich, Norbert; Saathoff, Elmar; Weller, Nina; Clowes, Petra; Kroidl, Inge; Ntinginya, Elias; Machibya, Harun; Maboko, Leonard; Loescher, Thomas; Dobler, Gerhard und Hoelscher, Michael
(2012):
High Seroprevalence of Rift Valley Fever and Evidence for Endemic Circulation in Mbeya Region, Tanzania, in a Cross-Sectional Study.
In: PLOS Neglected Tropical Diseases 6(3), e1557 [PDF, 3MB]
In: PLOS Neglected Tropical Diseases 6(3), e1557 [PDF, 3MB]
2011
Rachow, Andrea; Zumla, Alimuddin; Heinrich, Norbert; Rojas-Ponce, Gabriel; Mtafya, Bariki; Reither, Klaus; Ntinginya, Elias N.; O'Grady, Justin; Huggett, Jim; Dheda, Keertan; Boehme, Catharina; Perkins, Mark; Saathoff, Elmar und Hoelscher, Michael
(2011):
Rapid and accurate detection of Mycobacterium tuberculosis in sputum samples by Cepheid Xpert MTB/RIF assay--a clinical validation study.
In: PLOS ONE 6(6), e20458 [PDF, 154kB]
In: PLOS ONE 6(6), e20458 [PDF, 154kB]