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Veröffentlichungsdatum
Anzahl der Publikationen: 32
2024
Dyckhoff-Shen, Susanne 
ORCID: https://orcid.org/0000-0001-9247-4884; Koedel, Uwe; Brouwer, Matthijs C.; Bodilsen, Jacob und Klein, Matthias
(2024):
ChatGPT fails challenging the recent ESCMID brain abscess guideline.
In: Journal of Neurology, Bd. 271, Nr. 4: S. 2086-2101
[PDF, 489kB]
ORCID: https://orcid.org/0000-0001-9247-4884; Koedel, Uwe; Brouwer, Matthijs C.; Bodilsen, Jacob und Klein, Matthias
(2024):
ChatGPT fails challenging the recent ESCMID brain abscess guideline.
In: Journal of Neurology, Bd. 271, Nr. 4: S. 2086-2101
[PDF, 489kB]
Dyckhoff-Shen, Susanne; Bruegel, Mathias; Koedel, Uwe und Klein, Matthias
(2024):
Author reply to “reporting standards for cerebrospinal fluid studies: more transparency of laboratory data is needed” by JL Frater.
In: Infection, Bd. 52, Nr. 2: S. 697-698
[PDF, 299kB]
Dyckhoff-Shen, Susanne; Bewersdorf, Jan P.; Teske, Nina C.; Völk, Stefanie; Pfister, Hans-Walter; Koedel, Uwe und Klein, Matthias
(2024):
Characterization and diagnosis spectrum of patients with cerebrospinal fluid pleocytosis.
In: Infection, Bd. 52, Nr. 1: S. 219-229
[PDF, 662kB]
2022
Teske, Nina C.; Engelen-Lee, Joo-Yeon; Dyckhoff-Shen, Susanne; Pfister, Hans-Walter; Klein, Matthias; Beek, Diederik van de; Kirschning, Carsten K.; Koedel, Uwe und Brouwer, Matthijs C.
(2022):
The role of plasminogen activator inhibitor-2 in pneumococcal meningitis.
In: Acta Neuropathologica Communications, Bd. 10, Nr. 1, 155
Voelk, Stefanie; Koedel, Uwe; Pfister, Hans-Walter und Klein, Matthias
(2022):
Einfluss der COVID-19-Pandemie auf das Auftreten neuroinfektiologischer Erkrankungen.
In: Nervenarzt, Bd. 94, Nr. 4: S. 278-286
Volk, Stefanie; Koedel, Uwe; Horster, Sophia; Bayer, Andreas; D'Haese, Jan G.; Pfister, Hans-Walter und Klein, Matthias
(2022):
Patient disposition using the Emergency Severity Index: a retrospective observational study at an interdisciplinary emergency department.
In: BMJ Open, Bd. 12, Nr. 5
[PDF, 723kB]
Masouris, Ilias; Klein, Matthias; Angele, Barbara; Gross, Birgit; Goswami, Neha; Mashood, Fathima; Gesell Salazar, Manuela; Schubert, Soeren; Pfister, Hans-Walter; Koedel, Uwe und Schmidt, Frank
(2022):
Quantitative proteomic analysis of cerebrospinal fluid from patients with idiopathic facial nerve palsy.
In: European Journal of Neurology, Bd. 30, Nr. 4: S. 1048-1058
[PDF, 2MB]
Völk, Stefanie ORCID: https://orcid.org/0000-0001-6929-3831; Dobler, Fabian; Koedel, Uwe; Pfister, Hans-Walter; Brügel, Mathias; Schubert, Soeren und Klein, Matthias
(2022):
Cerebrospinal fluid analysis in emergency patients with suspected infection of the central nervous system.
In: European Journal of Neurology, Bd. 30, Nr. 3: S. 702-709
[PDF, 293kB]
ORCID: https://orcid.org/0000-0001-6929-3831; Dobler, Fabian; Koedel, Uwe; Pfister, Hans-Walter; Brügel, Mathias; Schubert, Soeren und Klein, Matthias
(2022):
Cerebrospinal fluid analysis in emergency patients with suspected infection of the central nervous system.
In: European Journal of Neurology, Bd. 30, Nr. 3: S. 702-709
[PDF, 293kB]
Völk, Stefanie; Koedel, Uwe; Pedersen, Vera; Weiglein, Tobias und Klein, Matthias
(2022):
Interdisziplinäre Notaufnahme: Geben Symptome und Zuweisungsweg Auskunft über den Bettenbedarf?
In: Notfall & Rettungsmedizin
[PDF, 462kB]
Völk, Stefanie ORCID: https://orcid.org/0000-0001-6929-3831; Pfirrmann, Markus; Koedel, Uwe; Pfister, Hans-Walter; Lang, Thomas; Scheibe, Franziska; Salih, Farid; Herzig-Nichtweiss, Julia; Zimmermann, Julian; Alonso, Angelika; Wittstock, Matthias; Totzeck, Andreas; Schramm, Patrick; Schirotzek, Ingo; Onur, Oezguer A.; Pelz, Johann Otto; Ottomeyer, Caroline; Luger, Sebastian; Barlinn, Kristian; Binder, Tobias; Wöbker, Gabriele; Reimann, Gernot; Urbanek, Christian; Heckelmann, Jan; Lochner, Piergiorgio; Berghoff, Martin; Schönenberger, Silvia; Neumann, Bernhard; Niesen, Wolf-Dirk; Dohmen, Christian; Huttner, Hagen B.; Günther, Albrecht und Klein, Matthias
(2022):
Decline in the number of patients with meningitis in German hospitals during the COVID-19 pandemic.
In: Journal of Neurology, Bd. 269: S. 3389-3399
[PDF, 715kB]
ORCID: https://orcid.org/0000-0001-6929-3831; Pfirrmann, Markus; Koedel, Uwe; Pfister, Hans-Walter; Lang, Thomas; Scheibe, Franziska; Salih, Farid; Herzig-Nichtweiss, Julia; Zimmermann, Julian; Alonso, Angelika; Wittstock, Matthias; Totzeck, Andreas; Schramm, Patrick; Schirotzek, Ingo; Onur, Oezguer A.; Pelz, Johann Otto; Ottomeyer, Caroline; Luger, Sebastian; Barlinn, Kristian; Binder, Tobias; Wöbker, Gabriele; Reimann, Gernot; Urbanek, Christian; Heckelmann, Jan; Lochner, Piergiorgio; Berghoff, Martin; Schönenberger, Silvia; Neumann, Bernhard; Niesen, Wolf-Dirk; Dohmen, Christian; Huttner, Hagen B.; Günther, Albrecht und Klein, Matthias
(2022):
Decline in the number of patients with meningitis in German hospitals during the COVID-19 pandemic.
In: Journal of Neurology, Bd. 269: S. 3389-3399
[PDF, 715kB]
2021
Masouris, Ilias; Manz, Kirsi ORCID: https://orcid.org/0000-0002-7740-4076; Pfirrmann, Markus; Dreyling, Martin; Angele, Barbara; Straube, Andreas; Langer, Sigrid; Huber, Marion; Koedel, Uwe und Baumgarten, Louisa von
(26. März 2021):
CXCL13 and CXCL9 CSF Levels in Central Nervous System Lymphoma-Diagnostic, Therapeutic, and Prognostic Relevance.
In: Frontiers in Neurology, Bd. 12, 654543
[PDF, 1MB]
ORCID: https://orcid.org/0000-0002-7740-4076; Pfirrmann, Markus; Dreyling, Martin; Angele, Barbara; Straube, Andreas; Langer, Sigrid; Huber, Marion; Koedel, Uwe und Baumgarten, Louisa von
(26. März 2021):
CXCL13 and CXCL9 CSF Levels in Central Nervous System Lymphoma-Diagnostic, Therapeutic, and Prognostic Relevance.
In: Frontiers in Neurology, Bd. 12, 654543
[PDF, 1MB]
Beek, Diederik van de; Brouwer, Matthijs C.; Koedel, Uwe und Wall, Emma C.
(2021):
Community-acquired bacterial meningitis.
In: Lancet, Bd. 398, Nr. 10306: S. 1171-1183
2020
Devraj, Gayatri; Guerit, Sylvaine; Seele, Jana; Spitzer, Daniel; Macas, Jadranka; Khel, Maryam; Heidemann, Roxana; Braczynskiz, Anne K.; Ballhorn, Wibke; Guenther, Stefan; Ogunshola, Omolara O.; Mittelbronn, Michel; Koedel, Uwe; Monoranu, Camelia M.; Plate, Karl H.; Hammerschmidt, Sven; Nau, Roland; Devraj, Kavi und Kempf, Volkhard A. J.
(2020):
HIF-1 alpha is involved in blood-brain barrier dysfunction and paracellular migration of bacteria in pneumococcal meningitis.
In: Acta Neuropathologica, Bd. 140, Nr. 2: S. 183-208
Klein, Matthias; Koedel, Uwe und Pfister, Hans-Walter
(2020):
Update wichtige ZNS-Infektionen.
In: Deutsche Medizinische Wochenschrift, Bd. 145, Nr. 3: S. 155-160
Ricci, Susanna; Grandgirard, Denis; Masouris, Ilias; Braccini, Tiziana; Pozzi, Gianni; Oggioni, Marco R.; Koedel, Uwe und Leib, Stephen L.
(2020):
Combined therapy with ceftriaxone and doxycycline does not improve the outcome of meningococcal meningitis in mice compared to ceftriaxone monotherapy.
In: BMC Infectious Diseases, Bd. 20, Nr. 1, 505
Masouris, Ilias; Klein, Matthias und Koedel, Uwe
(2020):
The potential for CXCL13 in CSF as a differential diagnostic tool in central nervous system infection.
In: Expert Review of Anti-Infective Therapy, Bd. 18, Nr. 9: S. 875-885
2018
Knier, Benjamin; Hiltensperger, Michael; Sie, Christopher; Aly, Lilian; Lepennetier, Gildas; Engleitner, Thomas; Garg, Garima; Muschaweckh, Andreas; Mitsdoerffer, Meike; Koedel, Uwe; Hoechst, Bastian; Knolle, Percy; Gunzer, Matthias; Hemmer, Bernhard; Rad, Roland; Merkler, Doron und Korn, Thomas
(2018):
Myeloid-derived suppressor cells control B cell accumulation in the central nervous system during autoimmunity.
In: Nature Immunology, Bd. 19, Nr. 12: S. 1341-1351
Fritscher, Johanna; Amberger, Daniel; Dyckhoff, Susanne; Bewersdorf, Jan Philipp; Masouris, Ilias; Voelk, Stefanie; Hammerschmidt, Sven; Schmetzer, Helga Maria; Klein, Matthias; Pfister, Hans-Walter und Koedel, Uwe
(2018):
Mast cells are activated by Streptococcus pneumoniae In Vitro but Dispensable for the host Defense against Pneumococcal central nervous system infection In Vivo.
In: Frontiers in Immunology, Bd. 9, 550
[PDF, 1MB]
Bewersdorf, Jan P.; Grandgirard, Denis; Koedel, Uwe und Leib, Stephen L.
(2018):
Novel and preclinical treatment strategies in pneumococcal meningitis.
In: Current Opinion in Infectious Diseases, Bd. 31, Nr. 1: S. 85-92
Rupprecht, Tobias Armin; Manz, Kirsi Marjaana ORCID: https://orcid.org/0000-0002-7740-4076; Fingerle, Volker; Lechner, Christian; Klein, Matthias; Pfirrmann, Markus und Koedel, Uwe
(2018):
Diagnostic value of cerebrospinal fluid CXCL13 for acute Lyme neuroborreliosis. A systemic review and meta-analysis.
In: Clinical Microbiology and infection
ORCID: https://orcid.org/0000-0002-7740-4076; Fingerle, Volker; Lechner, Christian; Klein, Matthias; Pfirrmann, Markus und Koedel, Uwe
(2018):
Diagnostic value of cerebrospinal fluid CXCL13 for acute Lyme neuroborreliosis. A systemic review and meta-analysis.
In: Clinical Microbiology and infection
2017
Masouris, Ilias; Klein, Matthias; Dyckhoff, Susanne; Angele, Barbara; Pfister, H. W. und Koedel, Uwe
(2017):
Inhibition of DAMP signaling as an effective adjunctive treatment strategy in pneumococcal meningitis.
In: Journal of Neuroinflammation
14:214
[PDF, 1MB]
2016
Buchholz, Grete; Koedel, Uwe; Pfister, Hans-Walter; Kastenbauer, Stefan und Klein, Matthias
(2. Oktober 2016):
Dramatic reduction of mortality in pneumococcal meningitis.
In: Critical Care
20:312
[PDF, 752kB]
Beek, Diederik van de; Brouwer, Matthijs; Hasbun, Rodrigo; Koedel, Uwe; Whitney, Cynthia G. und Wijdicks, Eelco
(2016):
Community-acquired bacterial meningitis.
In: Nature Reviews Disease Primers, Bd. 2, 16074
2015
Pruenster, Monika; Kurz, Angela R. M.; Chung, Kyoung-Jin; Cao-Ehlker, Xiao; Bieber, Stephanie; Nussbaum, Claudia F.; Bierschenk, Susanne; Eggersmann, Tanja K.; Rohwedder, Ina; Heinig, Kristina; Immler, Roland; Moser, Markus; Koedel, Uwe; Gran, Sandra; McEver, Rodger P.; Vestweber, Dietmar; Verschoor, Admar; Leanderson, Tomas; Chavakis, Triantafyllos; Roth, Johannes; Vogl, Thomas und Sperandio, Markus
(2015):
Extracellular MRP8/14 is a regulator of β2 integrin-dependent neutrophil slow rolling and adhesion.
In: Nature Communications, Bd. 6, 6915
[PDF, 784kB]
2014
Gerlini, Alice; Colomba, Leonarda; Furi, Leonardo; Braccini, Tiziana; Manso, Ana Sousa; Pammolli, Andrea; Wang, Bo; Vivi, Antonio; Tassini, Maria; Rooijen, Nico van; Pozzi, Gianni; Ricci, Susanna; Andrew, Peter W.; Koedel, Uwe; Moxon, E. Richard und Oggioni, Marco R.
(2014):
The Role of Host and Microbial Factors in the Pathogenesis of Pneumococcal Bacteraemia Arising from a Single Bacterial Cell Bottleneck.
In: PLOS Pathogens 10(3), e1004026 [PDF, 1MB]
In: PLOS Pathogens 10(3), e1004026 [PDF, 1MB]
Klein, Matthias; Brouwer, Matthijs C.; Angele, Barbara; Geldhoff, Madelijn; Marquez, Gabriel; Varona, Rosa; Haecker, Georg; Schmetzer, Helga; Häcker, Hans; Hammerschmidt, Sven; Ende, Arie van der; Pfister, Hans-Walter; Beek, Diederik van de und Koedel, Uwe
(2014):
Leukocyte Attraction by CCL20 and Its Receptor CCR6 in Humans and Mice with Pneumococcal Meningitis.
In: PLOS ONE 9(4), e93057 [PDF, 2MB]
In: PLOS ONE 9(4), e93057 [PDF, 2MB]
2011
Klein, Matthias; Koedel, Uwe; Pfefferkorn, Thomas; Zeller, Grete; Woehrl, Bianca und Pfister, Hans-Walter
(2011):
Arterial cerebrovascular complications in 94 adults with acute bacterial meningitis.
In: Critical Care
15:R281
[PDF, 248kB]
Demel, Cornelia; Hoegen, Tobias; Giese, Armin; Angele, Barbara; Pfister, Hans-Walter; Koedel, Uwe und Klein, Matthias
(2011):
Reduced spiral ganglion neuronal loss by adjunctive neurotrophin-3 in experimental pneumococcal meningitis.
In: Journal of Neuroinflammation
8:7
[PDF, 1MB]
2010
Blaser, Cornelia; Klein, Matthias; Grandgirard, Denis; Wittwer, Matthias; Peltola, Heikki; Weigand, Michael; Koedel, Uwe und Leib, Stephen L.
(2010):
Adjuvant glycerol is not beneficial in experimental pneumococcal meningitis.
In: BMC Infectious Diseases
10:84
[PDF, 282kB]
2009
Koedel, Uwe; Frankenberg, Tobias; Kirschnek, Susanne; Obermaier, Bianca; Häcker, Hans; Paul, Robert und Häcker, Georg
(Mai 2009):
Apoptosis is essential for neutrophil functional shutdown and determines tissue damage in experimental pneumococcal meningitis.
In: PLOS Pathogens 5(5), e1000461 [PDF, 1MB]
In: PLOS Pathogens 5(5), e1000461 [PDF, 1MB]
Rupprecht, Tobias A.; Plate, Andreas; Adam, Michaela; Wick, Manfed; Kastenbauer, Stefan; Schmidt, Caroline; Klein, Matthias; Pfister, Hans-Walter und Koedel, Uwe
(2009):
The chemokine CXCL13 is a key regulator of B cell recruitment to the cerebrospinal fluid in acute Lyme neuroborreliosis.
In: Journal of Neuroinflammation
6:42
[PDF, 354kB]
2007
Malipiero, Ursula; Koedel, Uwe; Pfister, Walter und Fontana, Adriano
(2007):
Bacterial meningitis: The role of transforming growth factor-beta in innate immunity and secondary brain damage.
In: Neurodegenerative Diseases, Nr. 1: S. 43-50
[PDF, 333kB]